Fragmentos solubles de la proteína PB2 del virus influenza con capacidad para unirse a un casquete de ARN.

Fragmento polipeptídico soluble de una subunidad PB2 de ARN-polimerasa dependiente de ARN del virus de la gripe,

en que dicho fragmento polipeptídico soluble es seleccionado del grupo consistente en:

(i) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 220 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 510 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o

(ii) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 222 del polipéptido de PB2 conforme a la SEQ ID N.º 2 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 511 del polipéptido de PB2 conforme a la SEQ ID N.º 2 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o

(iii) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 227 del polipéptido de PB2 conforme a la SEQ ID N.º 3 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 528 del polipéptido de PB2 conforme a la SEQ ID N.º 3 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o

(iv) un variante de fragmento polipeptídico, la cual mantiene una identidad de secuencia de como mínimo el 80% con el fragmento polipeptídico conforme a (i), (ii) o (iii)

y en la cual el fragmento polipeptídico conforme a (i), (ii) o (iii) o la variante de fragmento polipeptídico conforme a (iv) conserva la capacidad para asociarse con un casquete de ARN o un análogo de éste; en que el análogo del casquete de ARN se selecciona del grupo consistente en m7G, m7GMP, m7GTP, m7GpppN, m7GpppNm.

Fragmentos solubles de la proteína PB2 del virus influenza con capacidad para unirse a un casquete de ARN.

Campo técnico de la invención La presente invención se refiere a fragmentos solubles de la subunidad PB2 de la ARN-polimerasa dependiente de ARN del virus de la gripe y variantes de los mismos, así como a complejos cristalizados de los mismos que comprenden un análogo del casquete (CAP) de ARN. Esta invención también se refiere a métodos informáticos que utilizan las coordenadas estructurales de dicho complejo para el cribado y el diseño de compuestos que interaccionen con la cavidad de unión al casquete de ARN. Además, esta invención se refiere a métodos para identificar compuestos que se unan a fragmentos polipeptídicos de PB2 que comprendan la cavidad de unión al casquete de ARN, y que preferentemente inhiban la interacción con los casquetes de ARN o análogos de los mismos, mediante la utilización de dichos fragmentos polipeptídicos de PB2, preferentemente en un contexto de alto rendimiento. Los compuestos identificados de ese modo y las composiciones farmacéuticas que los contengan pueden ser utilizados para el tratamiento de enfermedades provocadas por infecciones víricas causadas por virus de ARN monocatenario de sentido negativo.

Antecedentes de la invención La gripe es responsable de una notable morbilidad y mortalidad en el mundo y es considerada por muchos como una de las enfermedades víricas más importantes del ser humano. Las epidemias anuales de gripe azotan el globo y de vez en cuando surgen nuevas cepas virulentas que provocan pandemias de gran poder destructivo. Actualmente la vacunación es el principal método para controlar las epidemias de la gripe. Pero surgen con rapidez nuevos virus de la gripe mutantes que eluden los efectos de la vacunación. En vista de que la fabricación de una nueva vacuna antigripal exige cerca de seis meses se requieren tratamientos alternativos, esto es, fármacos antivirales, sobre todo como primera línea de defensa contra las pandemias de rápida propagación.

Un excelente punto de partida para el desarrollo de fármacos antivirales son los datos estructurales de las proteínas esenciales de los virus. Por eso, la determinación de la estructura cristalina de la neuraminidasa, un antígeno de superficie del virus de la gripe (von Itzstein et al., 1993) condujo enseguida al desarrollo de inhibidores de la neuraminidasa con actividad antivírica que impiden la liberación del virus por parte de las células infectadas, aunque no la producción del mismo. Estos compuestos y sus derivados se desarrollaron posteriormente hasta convertirse en los antigripales zanamivir (Glaxo) y oseltamivir (Roche) , que muchos países están almacenando como primera línea de defensa contra una pandemia en el futuro. Con todo, estos medicamentos solo consiguen reducir la duración de la enfermedad clínica. Otros compuestos antigripales como la amantadina y la rimantadina tienen alternativamente como diana una proteína de los canales iónicos situada en la membrana del virus, la proteína M2, e interfieren en el proceso de descapsidación del virus en el interior de la célula. Pese a ello, no han sido utilizados ampliamente debido a sus efectos secundarios y la rápida aparición de virus mutantes resistentes (Magden et al., 2005) . Asimismo, fármacos antivirales más inespecíficos como la ribavirina han demostrado su eficacia como tratamiento antigripal (Eriksson et al., 1977) . No obstante, la ribavirina ha sido aprobada en pocos países, probablemente por la gravedad de los efectos secundarios (Furuta et al., 2005) . Así pues, existe una clara necesidad de nuevos compuestos antivirales, que preferentemente estén dirigidos contra dianas de otra naturaleza.

Los virus de la gripe integran con los Thogotovirus la familia de los Orthomyxoviridae que, junto con la familia Bunyaviridae, la cual engloba los géneros Hantavirus, Nairovirus, Orthobunyavirus y Phlebovirus, son virus de ARN de polaridad negativa. Su genoma está segmentado y agrupado en partículas de ribonucleoproteínas que incluyen la ARN-polimerasa dependiente de ARN encargada de: (i) el copiado inicial del ARN monocatenario del virión (ARNv) en ARNm del virus y (ii) la replicación del ARNv. A fin de sintetizar el ARNm del virus la polimerasa utiliza el mecanismo denominado "robo del casquete” (Plotch et al., 1981; Kukkonen et al., 2005; Leahy et al., 1997; Noah and Krug, 2005) . La enzima se une al casquete de ARN situado en el extremo 5' de las moléculas de ARNm de la célula y lo corta junto con un fragmento de nucleótidos. Los fragmentos de ARN dotados del casquete actúan como cebadores en la síntesis del ARNm del virus. La polimerasa está compuesta por tres subunidades: PB1 (proteína básica de la polimerasa) , PB2 y PA. La PB1 alberga las actividades endonucleasa y polimerasa y la PB2 contiene el dominio de unión al casquete de ARN.

El complejo polimerasa parece ser una diana adecuada para los fármacos antivirales porque es esencial para la síntesis del ARNm del virus y su replicación y porque contiene varios sitios activos funcionales que probablemente son considerablemente distintos de los presentes en las proteínas de las células hospedadoras (Magden et al., 2005) . Así, por ejemplo, ha habido intentos de interferir el ensamblaje de las subunidades de la polimerasa por medio de un péptido de 25 aminoácidos similar al dominio de unión a PA de la subunidad PB1 (Ghanem et al., 2007) . Asimismo se ha intentado bloquear la actividad endonucleasa de la polimerasa y persiguiendo ese fin se han descubierto una serie de compuestos derivados 4-sustituidos del ácido 2, 4-dioxobutanoico que actúan como inhibidores selectivos de la citada actividad en varios virus de la gripe (Tomassini et al., 1994) . La flutimida, una 2, 6dicetopiperazina sustituida descubierta en extractos del hongo Delitschia confertaspora, también inhibe la endonucleasa del virus de la gripe (Tomassini et al., 1996) . También se ha intentado interferir la transcripción vírica 2 5

con análogos de nucleósidos como la 2'-desoxi-2'-fluoroguanosina (Tisdale et al., 1995) y se ha demostrado que la T-705, una pirazina sustituida, puede actuar como inhibidor específico de la ARN-polimerasa del virus de la gripe (Furuta et al., 2005) . Por último, estudios comparativos del modo de unión de la proteína de unión al casquete humana eIF4E a estructuras de casquete de ARN y de la interacción de las RNP del virus de la gripe con estructuras de casquete de ARN (Hooker et al., 2003) permitieron descubrir un nuevo análogo de casquete que interacciona de forma selectiva con el virus de la gripe pero no con la proteína de unión al casquete humana. No obstante, hasta ahora el principal obstáculo para encontrar compuestos que interaccionasen con la cavidad de unión al casquete de ARN de PB2 y que pudieran interferir con la unión a dicho casquete y, por ende, con la actividad de la ARNpolimerasa era que se ignoraba la estructura y la identidad de esa cavidad de unión.

Los intentos por dilucidar el sitio de unión al casquete de ARN se han saldado con resultados contradictorios. Ciertos experimentos de entrecruzamiento indicaban que el sitio de unión al casquete de ARN de la ARN-polimerasa del virus de la gripe lo constituían dos secuencias distintas, una N-terminal (242-282) y otra C-terminal (538-577) del segmento proximal de PB2 (Honda et al., 1999) . Otros experimentos de entrecruzamiento hallaron una secuencia que abarcaba desde el aminoácido 533 al aminoácido 564 de la subunidad proteica PB2, en particular el residuo de aminoácido Trp552, como el sitio de interacción potencial con el casquete de ARN (Li et al., 2001) . Por su parte, un análisis mutacional señaló como posible sitio de unión al casquete de ARN los residuos de aminoácidos Phe363 y Phe404 de PB2 (Fechter et al., 2003) .

Uno de los objetos de la presente invención consiste en dar a conocer: (i) datos estructurales de alta resolución de la cavidad de unión al casquete de ARN de PB2 obtenidos mediante cristalografía de rayos X, (ii) métodos informáticos y métodos in vitro, preferentemente en un contexto de alto rendimiento, para identificar compuestos que pueden unirse a la cavidad de unión al ARN de PB2, preferentemente compitiendo en la unión al casquete de ARN con la ARN-polimerasa e interfiriendo así con su actividad, y (iii) composiciones farmacológicas que comprenden tales compuestos para el tratamiento de enfermedades infecciosas causadas por virus que utilizan el mecanismo de robo del casquete para la síntesis del ARNm del virus.

La presente invención hace posible por primera vez la definición precisa del sitio de unión al casquete de ARN de PB2 dentro de un dominio plegado independientemente. Hasta ahora la ubicación exacta del... [Seguir leyendo]

1. Fragmento polipeptídico soluble de una subunidad PB2 de ARN-polimerasa dependiente de ARN del virus de la gripe, en que dicho fragmento polipeptídico soluble es seleccionado del grupo consistente en:

(i) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 220 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 510 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o

(ii) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 222 del polipéptido de PB2 conforme a la SEQ ID N.º 2 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 511 del polipéptido de PB2 conforme a la SEQ ID N.º 2 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o

(iii) un fragmento polipeptídico cuyo extremo N-terminal está localizado en la posición de aminoácido 227 del polipéptido de PB2 conforme a la SEQ ID N.º 3 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o una posición de aminoácido superior; y cuyo extremo C-terminal está localizado en la posición de aminoácido 528 del polipéptido de PB2 conforme a la SEQ ID N.º 3 o en un residuo de aminoácido que ocupa una posición análoga en un polipéptido de PB2 alineado con ella o en una posición de aminoácido inferior; o (iv) un variante de fragmento polipeptídico, la cual mantiene una identidad de secuencia de como mínimo el 80% con el fragmento polipeptídico conforme a (i) , (ii) o (iii)

y en la cual el fragmento polipeptídico conforme a (i) , (ii) o (iii) o la variante de fragmento polipeptídico conforme a (iv) conserva la capacidad para asociarse con un casquete de ARN o un análogo de éste; en que el análogo del casquete de ARN se selecciona del grupo consistente en m7G, m7GMP, m7GTP, m7GpppN, m7GpppNm.

2. Fragmento polipeptídico de la reivindicación 1, en que dicho fragmento polipeptídico se selecciona del grupo consistente en:

(i) un fragmento polipeptídico con una secuencia de aminoácidos conforme a una de las SEQ ID N.º 4 a 13;

(ii) un fragmento polipeptídico con una secuencia de aminoácidos que abarca posiciones análogas en un polipéptido de PB2 alineado con una de las SEQ ID N.º 4 a 13; o

(iii) un variante de fragmento polipeptídico, que mantiene una identidad de secuencia de como mínimo el 80% con el fragmento polipeptídico de PB2 conforme a (i) o (ii) ;

y en la cual el fragmento polipeptídico conforme a (i) o (ii) o la variante de fragmento polipeptídico conforme a (iii) conserva la capacidad para asociarse con un casquete de ARN o un análogo de éste, en que el análogo del casquete de ARN se selecciona del grupo consistente en m7G, m7GMP, m7GTP, m7GpppN y m7GpppNm.

3. Complejo que comprende el fragmento polipeptídico de la reivindicación 1 o 2 y un casquete de ARN o un análogo de éste, en que el análogo del casquete de ARN se selecciona del grupo consistente en m7G, m7GMP, m7GTP, m7GpppN y m7GpppNm.

4. Complejo de la reivindicación 3, en que el análogo del casquete de ARN se selecciona del grupo consistente en m7GpppG, m7GpppGm, m7GpppA, m7GpppAm, m7GpppC, m7GpppCm, m7GpppU y m7GpppUm.

5. Complejo de la reivindicación 4, en que dicho fragmento polipeptídico consiste de una secuencia de aminoácidos conforme a la SEQ ID N.º 11 y dicho análogo de casquete de ARN es m7GTP, poseedor de la estructura definida por las coordenadas estructurales mostradas en la Figura 18.

6. Polinucleótido aislado que codifica un polipéptido aislado de la revindicación 1 o 2.

7. Vector recombinante que comprende el polinucleótido aislado de la reivindicación 6.

8. Célula hospedadora recombinante que comprende el polinucleótido aislado de la reivindicación 6 o el vector recombinante de la reivindicación 7.

9. Método para identificar compuestos que se asocian con toda o con parte de la cavidad de unión al casquete de ARN de un polipéptido de PB2 tal y como se define en las reivindicaciones 1 o 2, que comprende los siguientes pasos:

(a) construcción de un modelo informático de dicha cavidad de unión definido por las coordenadas estructurales del complejo de la reivindicación 5 tal y como se muestra en la Figura 18;

(b) selección de un compuesto de unión potencial mediante un método seleccionado del grupo consistente en:

(i) ensamblaje de fragmentos moleculares para formar dicho compuesto,

(ii) selección de un compuesto a partir de una base de datos de moléculas pequeñas, y

(iii) diseño de novo de ligandos de dicho compuesto;

(c) empleo de medios informáticos para llevar a cabo una operación de ajuste entre los modelos informáticos de dicho compuesto y dicha cavidad de unión con el fin de ofrecer una configuración de energía mínima de dicho compuesto en la cavidad de unión; y

(d) evaluación de los resultados de dicha operación de ajuste para cuantificar la asociación entre dicho compuesto y el modelo de cavidad de unión, en la cual se evalúa la capacidad de dicho compuesto para asociarse con dicha cavidad de unión, que es la estructura tridimensional formada por dicho polipéptido de PB2.

10. Método de la reivindicación 9, en que dicha cavidad de unión comprende: aminoácidos Phe323, His357 y Phe404 de PB2 conforme a la SEQ ID N.º 1 o los residuos de aminoácidos que ocupan una posición análoga en un polipéptido de PB2 alineado con ella.

11. Método de la reivindicación 10, en que dicha cavidad de unión comprende además opcionalmente:

(i) aminoácidos Phe325, Phe330 y Phe363 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o los residuos de aminoácidos que ocupan una posición análoga en un polipéptido de PB2 alineado con ella; y/o

(ii) aminoácidos Glu361 y Lys376 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o los residuos de aminoácidos que ocupan una posición análoga en un polipéptido de PB2 alineado con ella; y/o

(iii) aminoácidos Ser320, Arg332, Ser337 y Gln406 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o los residuos de aminoácidos que ocupan una posición análoga en un polipéptido de PB2 alineado con ella; y/o

(iv) aminoácidos Lys339, Arg355, Asn429 e His432 del polipéptido de PB2 conforme a la SEQ ID N.º 1 o los residuos de aminoácidos que ocupan una posición análoga en un polipéptido de PB2 alineado con ella.

12. Método para identificar compuestos que se asocian con la cavidad de unión al casquete de ARN del polipéptido PB2 tal y como se define en las reivindicaciones 1 o 2, que comprende los pasos consistentes en (i) poner en contacto dicho fragmento polipeptídico de la reivindicación 1 o 2 o dicha célula hospedadora recombinante conforme a la reivindicación 8 con un compuesto en estudio y (ii) analizar la capacidad de dicho compuesto en estudio para unirse a PB2.

13. Método de la reivindicación 12, que comprende el paso adicional de añadir un casquete de ARN o un análogo de éste.

14. Anticuerpo dirigido contra el dominio de unión al casquete de ARN de PB2, que es el polipéptido mínimo de PB2 que comprende la cavidad de unión al ARN y su estructura tridimensional original.

15. Anticuerpo de la reivindicación 14, en que dicho anticuerpo reconoce un fragmento polipeptídico seleccionado del grupo de polipéptidos definido por las SEQ ID N.º 14 a 22.

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COMPST --COMENT. 3

5 COMENT. 3 AFINAMIENTO

COMENT. 3 PROGRAMA : REFMAC 5.2.0019

COMENT. COMENT. 3 3 AUTORES : MURSHUDOV, VAGIN, DODSON

COMENT. 3 DIANA DE AFINAMIENTO : MÁXIMA VEROSIMILITUD

10 COMENT. 3

COMENT. 3 DATOS UTILIZADOS EN EL AFINAMIENTO

15 COMENT. COMENT. COMENT. COMENT. COMENT. 3 3 3 3 3 RANGO DE RESOLUCIÓN ALTO (ANGSTROMS) : 2.30 RANGO DE RESOLUCIÓN BAJO (ANGSTROMS) : 29.53 VALOR LÍMITE DE DATOS (SIGMA (F) ) : NINGUNO COMPLETITUD DEL RANGO (%) : 99.65 NÚMERO DE REFLEXIONES : 40781

COMENT. 3

COMENT. 3 AJUSTE A LOS DATOS UTILIZADOS EN EL AFINAMIENTO

COMENT. 3 MÉTODO DE VALIDACIÓN CRUZADA : TOTAL

20 COMENT. 3 SELECCIÓN DE CONFIG. DE PRUEBA DEL VALOR R-FREE : ALEATORIA

COMENT. COMENT. COMENT. 3 3 3 VALOR R (CONFIG. TRABAJO + PRUEBA) : 0.18859 VALOR R (CONFIG. TRABAJO) : 0.18611 VALOR FREE R : 0.23465

25 COMENT. COMENT. 3 3 TAMAÑO CONFIG. DEL PRUEBA DEL VALOR FREE R RECUENTO CONFIG. DE PRUEBA DEL VALOR R-FREE (%) :: 5.0 2165

COMENT. 3

COMENT. 3 ENCAJA EN LA CAPA DE MAYOR RESOLUCIÓN.

COMENT. 3 NÚMERO TOTAL DE CAPAS UTILIZADAS : 20

COMENT. 3 RANGO DE RESOLUCIÓN ALTO : 2.300

30 COMENT. 3 RANGO DE RESOLUCIÓN BAJO : 2.360

COMENT. COMENT. COMENT. COMENT. 3 3 3 3 REFLECCIÓN EN CAPA (CONFIG. TRABAJO) : 2984 COMPLETITUD DE CAPA (CONFIG. TRABAJO + PRUEBA) (%) : VALOR R DE CAPA (CONFIG. TRABAJO) : 0.250 RECUENTO CONFIG. VALOR FREE R : 148 98.55

35 COMENT. 3 VALOR FREE R DE CAPA : 0.312

COMENT. 3

COMENT. 3 NÚMERO DE ÁTOMOS UTILIZADOS EN EL REFINAMIENTO QUE NO SON ÁTOMOS DE HIDRÓGENO

COMENT. 3 TOTAL ÁTOMOS : 6926

40 COMENT. 3

COMENT. 3 VALORES B.

COMENT. COMENT. COMENT. 3 3 3 A PARTIR DEL CERO, GRAFÍCA DE WILSON VELOR B MEDIO (TOTAL, A**2) : 32.465 VALOR B ANISOTRÓPICO TOTAL. (A**2) : CERO

45 50 COMENT. COMENT. COMENT. COMENT. COMENT. COMENT. COMENT. 3 3 3 3 3 3 3 B11 (A**2) : B22 (A**2) : B33 (A**2) : B12 (A**2) : B13 (A**2) : B23 (A**2) : 0.44 0.68 -1.12 0.00 0.00 0.00

COMENT. 3 ERROR COORDENADAS TOTAL ESTIMADO.

55 COMENT. COMENT. COMENT. COMENT. COMENT. 3 3 3 3 3 ESU BASADO EN EL VALOR R (A) : 0.317 ESU BASADO EN EL VALOR R-FREE (A) : 0.227 ESU BASADO EN LA MÁXIMA VEROSIMILITUD (A) : 0.160 ESU DE LOS VALORES B BASADO EN LA MÁX. VEROSIMILITUD (A**2) : 13.245

COMENT. 3 COEFICIENTES DE CORRELACIÓN.

COMENT. 3 COEFICIENTES DE CORRELACIÓN FO-FC : 0.946

60 COMENT. 3 COEFICIENTES DE CORRELACIÓN FO-FC FREE : 0.920

COMENT. 3

COMENT. 3 DESVIACIONES RMS DE VALORES IDEALES RECUENTO RMS PESO

COMENT. 3 LONGITUDES DE ENLACE ÁTOMOS AFINADOS (A) : 6764 ; 0.013 ; 0.022COMENT. 3 ÁNGULOS DE ENLACE ÁTOMOS AFINADOS (GRADOS) : 9116 ; 1.519 ; 1.987COMENT. 3 ÁNGULOS DE TORSIÓN, PERÍODO 1 (GRADOS) : 823 ; 6.267 ; 5.000COMENT. 3 ÁNGULOS DE TORSIÓN, PERÍODO 2 (GRADOS) : 297 ;35.379 ;23.199COMENT. 3 ÁNGULOS DE TORSIÓN, PERÍODO 3 (GRADOS) : 1291 ;16.121 ;15.000COMENT. 3 ÁNGULOS DE TORSIÓN, PERÍODO 4 (GRADOS) : 62 ;18.647 ;15.000COMENT. 3 RESTRICCIONES DEL CENTRO QUIRAL (A**3) : 1027 ; 0.093 ; 0.200COMENT. 3 PLANOS GENERALES DE LOS ÁTOMOS AFINADOS (A) : 4923 ; 0.005 ;

0.020 COMENT. 3 CONTACTOS NO ENLAZADOS DE LOS ÁTOMOS AFINADOS (A) : 2631 ; 0.200 ;

0.200 COMENT. 3 TORSIÓN NO ENLAZADA DE LOS ÁTOMOS AFINADOS (A) : 4496 ; 0.292 ;

0.200 COMENT. 3 PUENTES DE H (X...Y) ÁTOMOS AFINADOS (A) : 321 ; 0.173 ; 0.200 COMENT. 3 VDW SIMETRÍA ÁTOMOS AFINADOS (A) : 124 ; 0.333 ; 0.200 COMENT. 3 SIMETRÍA PUENTES-H ÁTOMOS AFINADOS (A) : 17 ; 0.205 ; 0.200 COMENT. 3 COMENT. 3 RESTRICCIONES DEL FACTOR TÉRMICO ISOTRÓPICO. RECUENTO RMS PESO COMENT. 3 ENLACE CADENA PRINCIPAL ÁTOMOS AFINADOS (A**2) : 4221 ; 0.728 ;

1.500 COMENT. 3 ÁNGULO CADENA PRINCIPAL ÁTOMOS AFINADOS (A**2) : 6577 ; 1.124 ; 2.000 COMENT. 3 ENLACE CADENA LATERAL ÁTOMOS AFINADOS (A**2) : 2920 ; 2.095 ; 3.000 COMENT. 3 ÁNGULO CADENA LATERAL ÁTOMOS AFINADOS (A**2) : 2539 ; 3.232 ; 4.500 COMENT. 3 COMENT. 3 ESTADÍSTICAS RESTRICCIONES NCS COMENT. 3 NÚMERO DE GRUPOS NCS DISTINTOS : 1 COMENT. 3 COMENT. 3 NÚMERO DE GRUPO NCS : 1 COMENT. 3 NOMBRES DE CADENAS : B D E A COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO NCS : 9 COMENT. 3 COMPONENTE C SSSEQI A C SSSEQI CÓDIGO COMENT.3 1 B 323 B 330 1 COMENT.3 1 D 323 D 330 1 COMENT.3 1 E 323 E 330 1 COMENT.3 1 A 323 A 330 1 COMENT.3 2 B 333 B 340 1 COMENT.3 2 D 333 D 340 1 COMENT. 3 2 E 333 E 340 1 COMENT. 3 2 A 333 A 340 1 COMENT.3 3 B 350 B 368 1 COMENT.3 3 D 350 D 368 1 COMENT. 3 3 E 350 E 368 1 COMENT. 3 3 A 350 A 368 1 COMENT.3 4 B 370 B 389 1 COMENT.3 4 D 370 D 389 1 COMENT. 3 4 E 370 E 389 1 COMENT. 3 4 A 370 A 389 1 COMENT.3 5 B 393 B 407 1 COMENT.3 5 D 393 D 407 1 COMENT. 3 5 E 393 E 407 1 COMENT. 3 5 A 393 A 407 1 COMENT.3 6 B 411 B 420 1 COMENT.3 6 D 411 D 420 1 COMENT. 3 6 E 411 E 420 1 COMENT. 3 6 A 411 A 420 1 COMENT.3 7 B 428 B 434 1 COMENT.3 7 D 428 D 434 1 COMENT. 3 7 E 428 E 434 1 COMENT. 3 7 A 428 A 434 1 COMENT.3 8 B 443 B 451 1 COMENT.3 8 D 443 D 451 1 COMENT. 3 8 E 443 E 451 1 COMENT. 3 8 A 443 A 451 1

COMENT.3 9 B 455 B 482 1 COMENT.3 9 D 455 D 482 1 COMENT. 3 9 E 455 E 482 1 COMENT. 3 9 A 455 A 482 1 COMENT. 3 GRUPO CADENA RECUNTO RMS PESO COMENT. 3 POSICIONAL AJUSTADO 1 B (A) : 965 ; 0.05 ; 0.05 COMENT. 3 POSICIONAL AJUSTADO 1 D (A) : 965 ; 0.04 ; 0.05 COMENT. 3 POSICIONAL AJUSTADO 1 E (A) : 965 ; 0.05 ; 0.05 COMENT. 3 POSICIONAL AJUSTADO 1 A (A) : 965 ; 0.06 ; 0.05 COMENT. 3 TÉRMICO AJUSTADO 1 B (A**2) : 965 ; 1.46 ; 5.00 COMENT. 3 TÉRMICO AJUSTADO 1 D (A**2) : 965 ; 1.42 ; 5.00 COMENT. 3 TÉRMICO AJUSTADO 1 E (A**2) : 965 ; 1.17 ; 5.00 COMENT. 3 TÉRMICO AJUSTADO 1 A (A**2) : 965 ; 1.46 ; 5.00 COMENT. 3 COMENT. 3 COMENT. 3 DETALLES TLS COMENT. 3 NÚMERO DE GRUPOS TLS : 5 COMENT. 3 REGISTRO DE ÁTOMOS CONTIENE LA SUMA DE TLS Y LOS FACTORES B RESIDUALES COMENT. 3 REGISTRO DE ANISOU CONTIENE LA SUMA DE TLS Y LOS FACTORES U RESIDUALES COMENT. 3 COMENT. 3 GRUPO TLS : 1 COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO : 2 COMENT. 3 COMPONENTES C SSSEQI A C SSSEQICOMENT. 3 RANGO DE RESIDUO : A 320 A 483 COMENT. 3 RANGO DE RESIDUO : A 1 A 1 COMENT. 3 ORIGEN DEL GRUPO (A) : 35.1410 19.8550 -23.4970 COMENT. 3 TENSOR T COMENT. 3 T11: -0.1550 T22: -0.1929 COMENT. 3 T33: -0.1067 T12: 0.0176 COMENT. 3 T13: -0.0298 T23: 0.0184 COMENT. 3 TENSOR L COMENT. 3 L11: 2.3533 L22: 1.7075 COMENT. 3 L33: 2.2571 L12: 0.0348 COMENT. 3 L13: -0.0773 L23: 0.5035 COMENT. 3 TENSOR S COMENT. 3 S11: 0.0055 S12: 0.1725 S13: 0.1938 COMENT. 3 S21: -0.0821 S22: 0.0154 S23: -0.0549 COMENT. 3 S31: 0.0216 S32: 0.1221 S33: -0.0208 COMENT. 3 COMENT. 3 GRUPO TLS : 2 COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO : 2 COMENT. 3 COMPONENTES C SSSEQI A C SSSEQICOMENT. 3 RANGO DE RESIDUO : B 320 B 483 COMENT. 3 RANGO DE RESIDUO : B 1 B 1 COMENT. 3 ORIGEN DEL GRUPO (A) : 12.4750 -3.5580 -19.4120 COMENT. 3 TENSOR T COMENT. 3 T11: -0.1896 T22: -0.1182 COMENT. 3 T33: -0.0978 T12: -0.0381 COMENT. 3 T13: -0.0171 T23: -0.0637 COMENT. 3 TENSOR L COMENT. 3 L11: 1.9172 L22: 2.6126 COMENT. 3 L33: 3.6260 L12: 0.0348 COMENT. 3 L13: -0.2423 L23: -0.1860 COMENT. 3 TENSOR S COMENT. 3 S11: -0.0729 S12: 0.1999 S13: -0.0806 COMENT. 3 S21: -0.0771 S22: 0.0269 S23: 0.2153 COMENT. 3 S31: 0.1325 S32: -0.3438 S33: 0.0460 COMENT. 3 COMENT. 3 GRUPO TLS : 3 COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO : 2 COMENT. 3 COMPONENTES C SSSEQI A C SSSEQICOMENT. 3 RANGO DE RESIDUO : D 319 D 483

COMENT. 3 RANGO DE RESIDUO : D 1 D 1

COMENT. COMENT. 3 3 ORIGEN DEL GRUPO (A) : 58.8840 -3.4260 -19.4800 TENSOR T

COMENT. 3 T11: -0.2007 T22: -0.1084

COMENT. 3 T33: -0.1629 T12: 0.0008

COMENT. 3 T13: 0.0350 T23: -0.0105

COMENT. 3 TENSOR L

COMENT. 3 L11: 2.5312 L22: 3.5830

COMENT. 3 L33: 2.7686 L12: -0.2516

COMENT. 3 L13: -0.0723 L23: 0.1658

COMENT. 3 TENSOR S

COMENT. 3 S11: 0.0281 S12: 0.3485 S13: -0.0276

COMENT. 3 S21: -0.3438 S22: -0.1013 S23: -0.1815

COMENT. 3 S31: 0.0548 S32: -0.1509 S33: 0.0732

COMENT. 3

COMENT. 3 GROUP TLS : 4

COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO : 2

COMENT. COMENT. 3 3 COMPONENTS C SSSEQI A C SSSEQIRANGO DE RESIDUO : E 320 E 483

COMENT. 3 RANGO DE RESIDUO : E 1 E 1

COMENT. COMENT. 3 3 ORIGEN DEL GRUPO (A) : 35.6570 -25.9320 -15.2800 TENSOR T

COMENT. 3 T11: -0.0768 T22: -0.2139

COMENT. 3 T33: -0.0804 T12: -0.0233

COMENT. 3 T13: 0.0636 T23: -0.0476

COMENT. 3 TENSOR L

COMENT. 3 L11: 3.7194 L22: 2.4929

COMENT. 3 L33: 2.9822 L12: 0.6274

COMENT. 3 L13: 0.2948 L23: 1.0025

COMENT. 3 TENSOR S

COMENT. 3 S11: -0.0484 S12: 0.3196 S13: -0.2371

COMENT. 3 S21: -0.1986 S22: 0.0864 S23: -0.0561

COMENT. 3 S31: 0.1208 S32: 0.1243 S33: -0.0380

COMENT. 3

COMENT. 3 GRUPO TLS : 5

COMENT. 3 NÚMERO DE COMPONENTES DEL GRUPO : 2

COMENT. COMENT. 3 3 COMPONENTS C SSSEQI A C SSSEQI RANGO DE RESIDUO : F 322 F 483

COMENT. 3 RANGO DE RESIDUO : F 1 F 1

COMENT. COMENT. 3 3 ORIGEN DEL GRUPO (A) : 29.6550 -7.6170 -50.4960 TENSOR T

COMENT. 3 T11: 0.0277 T22: 0.2406

COMENT. 3 T33: -0.1217 T12: 0.0164

COMENT. 3 T13: -0.0146 T23: -0.0766

COMENT. 3 TENSOR L

COMENT. 3 L11: 2.4339 L22: 4.7601

COMENT. 3 L33: 4.8718 L12: 0.4947

COMENT. 3 L13: -0.0699 L23: 1.5231

COMENT. 3 TENSOR S

COMENT. 3 S11: -0.0489 S12: 0.5805 S13: -0.1649

COMENT. 3 S21: -0.2269 S22: 0.0375 S23: -0.0293

COMENT. 3 S31: 0.2872 S32: 0.3181 S33: 0.0114

COMENT. 3

COMENT. 3

COMENT. 3 MODELIZACIÓN DEL SOLVENTE GRANEL.

COMENT. 3 MÉTODO UTILIZADO : MÁSCARA

COMENT. 3 PARÁMETROS PARA EL CÁLCULO DE LA MÁSCARA

COMENT. 3 RADIO SONDA VDW : 1.40

COMENT. 3 RADIO SONDA ION : 0.80

COMENT. 3 RADIO CONTRACCIÓN : 0.80

COMENT. 3

COMENT. 3 OTROS COMENTARIOS DE AFINAMIENTO.S:

COMENT. 3 SE HAN AÑADIDO HIDRÓGENOS EN LAS POSICIONES SOLAPADAS

COMENT. 3

LINK LINK LINK CRYST1 92.200 VAL B 421 ASN E 422 ASN F 422 94.440 220.400 90.00 ALA B 424 ARG E 427 ASN F 425 90.00 90.00 C 2 2 21 gapgapgap

SCALE1 0.010846 0.000000 0.000000 0.00000

SCALE2 0.000000 0.010589 0.000000 0.00000

SCALE3 0.000000 0.000000 0.004537 0.00000

ATOM 1 N SER A 320 54.724 26.969 -16.114 1.00 49.27 N

ANISOU 1 N SER A 320 4119 7020 7581 -643 -576 -957 N

ATOM 2 CA SER A 320 53.387 26.747 -16.772 1.00 47.48 C

ANISOU 2 CA SER A 320 4127 6616 7296 -583 -499 -811 C

ATOM 3 CB SER A 320 52.263 27.451 -15.989 1.00 46.88 C

ANISOU 3 CB SER A 320 4227 6364 7221 -625 -539 -825 C

ATOM 4 OG SER A 320 51.912 26.737 -14.806 1.00 47.95 O

ANISOU 4 OG SER A 320 4428 6550 7242 -485 -673 -881 O

ATOM 5 C SER A 320 53.375 27.229 -18.230 1.00 47.12 C

ANISOU 5 C SER A 320 4085 6503 7314 -693 -330 -697 C

ATOM 6 O SER A 320 54.163 28.116 -18.614 1.00 48.38 O

ANISOU 6 O SER A 320 4111 6684 7588 -870 -256 -724 O

ATOM 7 N SER A 321 52.500 26.617 -19.034 1.00 44.78 N

ANISOU 7 N SER A 321 3940 6137 6937 -592 -270 -571 N

ATOM 8 CA SER A 321 52.188 27.123 -20.378 1.00 43.99 C

ANISOU 8 CA SER A 321 3899 5951 6864 -686 -122 -442 C

ATOM 9 CB SER A 321 52.645 26.139 -21.481 1.00 44.33 C

ANISOU 9 CB SER A 321 3883 6132 6831 -594 -42 -388 C

ATOM 10 OG SER A 321 51.642 25.165 -21.790 1.00 44.54 O

ANISOU 10 OG SER A 321 4074 6110 6740 -434 -58 -318 O

ATOM 11 C SER A 321 50.674 27.446 -20.489 1.00 41.02 C

ANISOU 11 C SER A 321 3753 5371 6461 -667 -116 -344 C

ATOM 12 O SER A 321 49.828 26.667 -20.050 1.00 38.76 O

ANISOU 12 O SER A 321 3585 5058 6085 -525 -186 -338 O

ATOM 13 N SER A 322 50.365 28.608 -21.063 1.00 39.94 N

ANISOU 13 N SER A 322 3672 5093 6409 -814 -31 -267 N

ATOM 14 CA SER A 322 48.990 29.066 -21.192 1.00 37.50 C

ANISOU 14 CA SER A 322 3558 4592 6098 -798 -28 -177 C

ATOM 15 CB SER A 322 48.780 30.408 -20.502 1.00 38.36 C

ANISOU 15 CB SER A 322 3699 4533 6342 -928 -45 -227 C

ATOM 16 OG SER A 322 48.807 30.236 -19.105 1.00 41.26 O

ANISOU 16 OG SER A 322 4040 4932 6704 -882 -161 -379 O

ATOM 17 C SER A 322 48.540 29.176 -22.627 1.00 35.90 C

ANISOU 17 C SER A 322 3439 4343 5858 -813 81 -11 C

ATOM 18 O SER A 322 49.323 29.452 -23.543 1.00 36.92 O

ANISOU 18 O SER A 322 3488 4535 6006 -912 183 47 O

ATOM 19 N PHE A 323 47.261 28.915 -22.811 1.00 32.90 N

ANISOU 19 N PHE A 323 3216 3870 5414 -714 56 62 N

ATOM 20 CA PHE A 323 46.611 29.195 -24.077 1.00 31.70 C

ANISOU 20 CA PHE A 323 3167 3652 5224 -726 134 223 C

ATOM 21 CB PHE A 323 46.730 28.032 -25.092 1.00 30.07 C

ANISOU 21 CB PHE A 323 2953 3600 4872 -634 177 274 C

ATOM 22 CG PHE A 323 46.322 26.714 -24.552 1.00 27.72 C

ANISOU 22 CG PHE A 323 2678 3371 4481 -474 93 196 C

ATOM 23 CD1 PHE A 323 45.030 26.271 -24.707 1.00 25.75 C

ANISOU 23 CD1 PHE A 323 2566 3057 4162 -378 53 245 C

ATOM 24 CE1 PHE A 323 44.642 25.070 -24.196 1.00 24.05 C

ANISOU 24 CE1 PHE A 323 2380 2888 3871 -251 -15 180 C

ATOM 25 CZ PHE A 323 45.541 24.275 -23.524 1.00 24.93 C

ANISOU 25 CZ PHE A 323 2397 3105 3969 -195 -52 76 C

ATOM 26 CE2 PHE A 323 46.840 24.686 -23.357 1.00 25.71 C

ANISOU 26 CE2 PHE A 323 2350 3285 4133 -269 -26 23 C

ATOM 27 CD2 PHE A 323 47.234 25.908 -23.874 1.00 28.00 C

ANISOU 27 CD2 PHE A 323 2597 3536 4504 -418 51 77 C

ATOM 28 C PHE A 323 45.163 29.568 -23.830 1.00 29.89 C

ANISOU 28 C PHE A 323 3093 3256 5008 -667 82 270 C

ATOM 29 O PHE A 323 44.616 29.366 -22.743 1.00 29.10 O

ANISOU 29 O PHE A 323 3023 3117 4917 -600 -3 175 O

ATOM 30 N SER A 324 44.553 30.095 -24.867 1.00 29.85 N

ANISOU 30 N SER A 324 3182 3167 4994 -688 135 420 N

ATOM 31 CA SER A 324 43.159 30.471 -24.844 1.00 30.29 C

ANISOU 31 CA SER A 324 3369 3076 5062 -621 90 481 C

ATOM 32 CB SER A 324 43.035 31.897 -25.367 1.00 32.34 C

ANISOU 32 CB SER A 324 3691 3160 5436 -725 143 602 C

ATOM 33 OG SER A 324 41.869 32.520 -24.855 1.00 36.69 O

ANISOU 33 OG SER A 324 4337 3538 6064 -667 84 602 O

ATOM 34 C SER A 324 42.357 29.507 -25.724 1.00 28.87 C

ANISOU 34 C SER A 324 3257 2982 4731 -505 81 560 C

ATOM 35 O SER A 324 42.760 29.221 -26.855 1.00 29.40 O

ANISOU 35 O SER A 324 3315 3147 4709 -524 146 648 O

ATOM 36 N PHE A 325 41.252 28.971 -25.199 1.00 26.88 N

ANISOU 36 N PHE A 325 3064 2706 4445 -394 5 517 N

ATOM 37 CA PHE A 325 40.371 28.148 -25.992 1.00 25.57 C

ANISOU 37 CA PHE A 325 2960 2603 4153 -299 -13 580 C

ATOM 38 CB PHE A 325 40.776 26.659 -25.905 1.00 24.87 C

ANISOU 38 CB PHE A 325 2828 2671 3952 -233 -24 493 C

ATOM 39 CG PHE A 325 39.944 25.733 -26.769 1.00 23.25 C

ANISOU 39 CG PHE A 325 2684 2533 3617 -152 -40 535 C

ATOM 40 CD1 PHE A 325 40.003 25.815 -28.165 1.00 25.46 C

ANISOU 40 CD1 PHE A 325 2990 2876 3809 -171 12 645 C

ATOM 41 CE1 PHE A 325 39.243 24.954 -28.976 1.00 23.62 C

ANISOU 41 CE1 PHE A 325 2810 2717 3447 -102 -11 664 C

ATOM 42 CZ PHE A 325 38.430 23.990 -28.377 1.00 23.09 C

ANISOU 42 CZ PHE A 325 2768 2648 3358 -24 -79 576 C

ATOM 43 CE2 PHE A 325 38.359 23.916 -26.980 1.00 19.84 C

ANISOU 43 CE2 PHE A 325 2336 2168 3036 -9 -119 485 C

ATOM 44 CD2 PHE A 325 39.118 24.773 -26.195 1.00 20.21 C

ANISOU 44 CD2 PHE A 325 2332 2156 3190 -67 -102 463 C

ATOM 45 C PHE A 325 38.945 28.342 -25.493 1.00 25.59 C

ANISOU 45 C PHE A 325 3035 2502 4189 -224 -81 574 C

ATOM 46 O PHE A 325 38.673 28.189 -24.307 1.00 24.95 O

ANISOU 46 O PHE A 325 2941 2388 4150 -195 -126 462 O

ATOM 47 N GLY A 326 38.032 28.646 -26.416 1.00 25.94 N

ANISOU 47 N GLY A 326 3147 2510 4200 -188 -90 693 N

ATOM 48 CA GLY A 326 36.612 28.725 -26.111 1.00 25.17 C

ANISOU 48 CA GLY A 326 3096 2344 4125 -103 -155 690 C

ATOM 49 C GLY A 326 36.229 29.790 -25.105 1.00 26.10 C

ANISOU 49 C GLY A 326 3221 2299 4397 -108 -174 641 C

ATOM 50 O GLY A 326 35.223 29.646 -24.422 1.00 25.44 O

ANISOU 50 O GLY A 326 3144 2187 4334 -38 -220 574 O

ATOM 51 N GLY A 327 37.027 30.862 -25.017 1.00 27.43 N

ANISOU 51 N GLY A 327 3385 2361 4675 -198 -132 664 N

ATOM 52 CA GLY A 327 36.814 31.912 -24.021 1.00 27.22 C

ANISOU 52 CA GLY A 327 3367 2168 4806 -214 -145 590 C

ATOM 53 C GLY A 327 37.405 31.621 -22.645 1.00 26.92 C

ANISOU 53 C GLY A 327 3269 2165 4793 -247 -155 409 C

ATOM 54 O GLY A 327 37.162 32.382 -21.694 1.00 27.56 O

ANISOU 54 O GLY A 327 3357 2128 4986 -254 -170 314 O

ATOM 55 N PHE A 328 38.164 30.521 -22.524 1.00 25.21 N

ANISOU 55 N PHE A 328 2998 2113 4470 -258 -153 357 N

ATOM 56 CA PHE A 328 38.854 30.196 -21.271 1.00 24.27 C

ANISOU 56 CA PHE A 328 2818 2049 4354 -284 -175 202 C

ATOM 57 CB PHE A 328 38.420 28.823 -20.748 1.00 21.36 C

ANISOU 57 CB PHE A 328 2450 1807 3859 -193 -216 141 C

ATOM 58 CG PHE A 328 37.002 28.783 -20.278 1.00 21.75 C

ANISOU 58 CG PHE A 328 2552 1805 3906 -115 -245 118 C

ATOM 59 CD1 PHE A 328 36.703 28.945 -18.927 1.00 20.12 C

ANISOU 59 CD1 PHE A 328 2344 1576 3724 -103 -269 -11 C

ATOM 60 CE1 PHE A 328 35.409 28.928 -18.474 1.00 18.66 C

ANISOU 60 CE1 PHE A 328 2192 1359 3539 -36 -280 -42 C

ATOM 61 CZ PHE A 328 34.350 28.706 -19.370 1.00 19.24 C

ANISOU 61 CZ PHE A 328 2291 1424 3594 24 -280 54 C

ATOM 62 CE2 PHE A 328 34.621 28.534 -20.739 1.00 19.65 C

ANISOU 62 CE2 PHE A 328 2351 1500 3614 16 -271 184 C

ATOM 63 CD2 PHE A 328 35.943 28.578 -21.186 1.00 20.82 C

ANISOU 63 CD2 PHE A 328 2476 1679 3755 -53 -247 216 C

ATOM 64 C PHE A 328 40.359 30.228 -21.450 1.00 24.86 C

ANISOU 64 C PHE A 328 2812 2194 4438 -383 -140 189 C

ATOM 65 O PHE A 328 40.866 29.801 -22.489 1.00 25.40 O

ANISOU 65 O PHE A 328 2860 2349 4442 -398 -98 278 O

ATOM 66 N THR A 329 41.061 30.721 -20.433 1.00 25.87 N

ANISOU 66 N THR A 329 2885 2302 4643 -451 -157 64 N

ATOM 67 CA THR A 329 42.516 30.587 -20.320 1.00 26.02 C

ANISOU 67 CA THR A 329 2793 2427 4668 -537 -143 9 C

ATOM 68 CB THR A 329 43.119 31.743 -19.510 1.00 27.28 C

ANISOU 68 CB THR A 329 2908 2490 4967 -657 -149 -100 C

ATOM 69 OG1 THR A 329 42.778 32.984 -20.135 1.00 28.71 O

ANISOU 69 OG1 THR A 329 3154 2479 5276 -731 -95 -9 O

ATOM 70 CG2 THR A 329 44.634 31.634 -19.423 1.00 28.51 C

ANISOU 70 CG2 THR A 329 2923 2773 5137 -755 -139 -164 C

ATOM 71 C THR A 329 42.803 29.250 -19.623 1.00 25.30 C

ANISOU 71 C THR A 329 2656 2504 4453 -448 -202 -77 C

ATOM 72 O THR A 329 42.381 29.020 -18.481 1.00 24.62 O

ANISOU 72 O THR A 329 2591 2422 4339 -397 -263 -177 O

ATOM 73 N PHE A 330 43.508 28.370 -20.328 1.00 25.13 N

ANISOU 73 N PHE A 330 2578 2617 4353 -425 -178 -34 N

ATOM 74 CA PHE A 330 44.004 27.109 -19.781 1.00 23.76 C

ANISOU 74 CA PHE A 330 2354 2594 4080 -338 -231 -105 C

ATOM 75 CB PHE A 330 44.025 26.057 -20.885 1.00 22.27 C

ANISOU 75 CB PHE A 330 2176 2492 3794 -266 -193 -21 C

ATOM 76 CG PHE A 330 42.680 25.488 -21.239 1.00 20.53 C

ANISOU 76 CG PHE A 330 2078 2221 3502 -181 -200 43 C

ATOM 77 CD1 PHE A 330 42.392 24.145 -20.983 1.00 19.04 C

ANISOU 77 CD1 PHE A 330 1924 2097 3213 -73 -240 19 C

ATOM 78 CE1 PHE A 330 41.140 23.599 -21.356 1.00 18.69 C

ANISOU 78 CE1 PHE A 330 1982 2010 3110 -244 70 C

ATOM 79 CZ PHE A 330 40.183 24.409 -21.969 1.00 16.45 C

ANISOU 79 CZ PHE A 330 1753 1636 2861 -47 -219 144 C

ATOM 80 CE2 PHE A 330 40.483 25.735 -22.229 1.00 17.52 C

ANISOU 80 CE2 PHE A 330 1861 1702 3092 -134 -185 180 C

ATOM 81 CD2 PHE A 330 41.712 26.267 -21.870 1.00 18.89 C

ANISOU 81 CD2 PHE A 330 1947 1901 3330 -209 -170 131 C

ATOM 82 C PHE A 330 45.442 27.334 -19.342 1.00 25.60 C

ANISOU 82 C PHE A 330 2443 2923 4362 -411 -244 -196 C

ATOM 83 O PHE A 330 46.220 27.886 -20.103 1.00 26.69 O

ANISOU 83 O PHE A 330 2504 3075 4562 -509 -176 -160 O

ATOM 84 N LYS A 331 45.798 26.952 -18.116 1.00 26.58 N

ANISOU 84 N LYS A 331 2524 3119 4455 -370 -331 -311 N

ATOM 85 CA LYS A 331 47.198 26.814 -17.729 1.00 28.34 C

ANISOU 85 CA LYS A 331 2589 3483 4695 -400 -366 -401 C

ATOM 86 CB LYS A 331 47.576 27.791 -16.597 1.00 29.96 C

ANISOU 86 CB LYS A 331 2740 3665 4978 -499 -424 -533 C

ATOM 87 CG LYS A 331 46.950 29.141 -16.805 1.00 33.02 C

ANISOU 87 CG LYS A 331 3199 3864 5484 -618 -366 -514 C

ATOM 88 CD LYS A 331 47.691 30.310 -16.166 1.00 36.96 C

ANISOU 88 CD LYS A 331 3609 4328 6108 -772 -384 -641 C

ATOM 89 CE LYS A 331 46.932 31.614 -16.487 1.00 38.10 C

ANISOU 89 CE LYS A 331 3856 4240 6381 -869 -318 -602 C

ATOM 90 NZ LYS A 331 45.453 31.490 -16.098 1.00 35.18 N

ANISOU 90 NZ LYS A 331 3643 3766 5958 -754 -340 -582 N

ATOM 91 C LYS A 331 47.426 25.382 -17.285 1.00 27.41 C

ANISOU 91 C LYS A 331 2461 3496 4457 -247 -438 -423 C

ATOM 92 O LYS A 331 46.686 24.886 -16.436 1.00 26.89 O

ANISOU 92 O LYS A 331 2493 3409 4316 -163 -502 -440 O

ATOM 93 N ARG A 332 48.430 24.719 -17.857 1.00 27.61 N

ANISOU 93 N ARG A 332 2371 3651 4467 -207 -422 -419 N

ATOM 94 CA ARG A 332 48.758 23.355 -17.455 1.00 27.40 C

ANISOU 94 CA ARG A 332 2331 3735 4345 -47 -494 -440 C

ATOM 95 CB ARG A 332 49.602 22.651 -18.535 1.00 28.32 C

ANISOU 95 CB ARG A 332 2347 3958 4456 6 -433 -413 C

ATOM 96 CG ARG A 332 49.838 21.151 -18.250 1.00 27.07 C

ANISOU 96 CG ARG A 332 2199 3876 4209 196 -503 -424 C

ATOM 97 CD ARG A 332 50.442 20.434 -19.426 1.00 28.72 C

ANISOU 97 CD ARG A 332 2338 4163 4411 261 -425 -404 C

ATOM 98 NE ARG A 332 51.692 21.044 -19.875 1.00 33.91 N

ANISOU 98 NE ARG A 332 2788 4950 5147 174 -371 -457 N

ATOM 99 CZ ARG A 332 52.274 20.789 -21.043 1.00 34.89 C

ANISOU 99 CZ ARG A 332 2824 5156 5276 178 -265 -445 C

ATOM 100 NH1 ARG A 332 51.722 19.917 -21.900 1.00 36.69 N

ANISOU 100 NH1 ARG A 332 3162 5348 5430 273 -212 -393 N

ATOM 101 NH2 ARG A 332 53.401 21.404 -21.362 1.00 33.49 N

ANISOU 101 NH2 ARG A 332 2447 5104 5173 80 -208 -495 N

ATOM 102 C ARG A 332 49.478 23.325 -16.100 1.00 28.09 C

ANISOU 102 C ARG A 332 2332 3923 4419 -22 -617 -552 C

ATOM 103 O ARG A 332 50.525 23.979 -15.940 1.00 29.61 O

ANISOU 103 O ARG A 332 2361 4203 4686 -112 -631 -634 O

ATOM 104 N THR A 333 48.919 22.570 -15.143 1.00 26.95 N

ANISOU 104 N THR A 333 2293 3774 4172 91 -705 -554 N

ATOM 105 CA THR A 333 49.474 22.450 -13.787 1.00 27.54 C

ANISOU 105 CA THR A 333 2315 3954 4195 133 -836 -647 C

ATOM 106 CB THR A 333 48.388 22.724 -12.718 1.00 27.54 C

ANISOU 106 CB THR A 333 2466 3874 4125 122 -877 -663 C

ATOM 107 OG1 THR A 333 47.269 21.862 -12.950 1.00 25.80 O

ANISOU 107 OG1 THR A 333 2413 3561 3829 209 -841 -558 O

ATOM 108 CG2 THR A 333 47.898 24.155 -12.811 1.00 27.45 C

ANISOU 108 CG2 THR A 333 2468 3750 4212 -40 -814 -706 C

ATOM 109 C THR A 333 50.166 21.106 -13.487 1.00 28.06 C

ANISOU 109 C THR A 333 2339 4142 4179 311 -925 -636 C

ATOM 110 O THR A 333 50.964 21.028 -12.549 1.00 29.37 O

ANISOU 110 O THR A 333 2410 4438 4313 352 -1042 -713 O

ATOM 111 N SER A 334 49.860 20.070 -14.277 1.00 27.10 N

ANISOU 111 N SER A 334 2292 3978 4028 420 -875 -547 N

ATOM 112 CA SER A 334 50.480 18.728 -14.162 1.00 27.68 C

ANISOU 112 CA SER A 334 2343 4130 4045 606 -945 -529 C

ATOM 113 CB SER A 334 49.626 17.789 -13.327 1.00 26.96 C

ANISOU 113 CB SER A 334 2442 3966 3835 718 -1011 -462 C

ATOM 114 OG SER A 334 50.099 17.727 -12.010 1.00 30.72 O

ANISOU 114 OG SER A 334 2890 4542 4239 772 -1148 -505 O

ATOM 115 C SER A 334 50.552 18.102 -15.525 1.00 26.76 C

ANISOU 115 C SER A 334 2220 3985 3963 656 -843 -480 C

ATOM 116 O SER A 334 49.729 18.424 -16.392 1.00 25.27 O

ANISOU 116 O SER A 334 2118 3691 3794 573 -735 -429 O

ATOM 117 N GLY A 335 51.514 17.201 -15.702 1.00 27.29 N

ANISOU 117 N GLY A 335 2187 4150 4033 801 -881 -502 N

ATOM 118 CA GLY A 335 51.543 16.328 -16.851 1.00 27.54 C

ANISOU 118 CA GLY A 335 2237 4152 4073 890 -798 -470 C

ATOM 119 C GLY A 335 52.108 16.996 -18.081 1.00 28.17 C

ANISOU 119 C GLY A 335 2172 4300 4230 785 -672 -502 C

ATOM 120 O GLY A 335 52.658 18.070 -18.002 1.00 28.84 O

ANISOU 120 O GLY A 335 2118 4461 4377 651 -657 -549 O

ATOM 121 N SER A 336 51.966 16.334 -19.225 1.00 29.01 N

ANISOU 121 N SER A 336 2317 4378 4327 841 -577 -478 N

ATOM 122 CA SER A 336 52.594 16.734 -20.488 1.00 29.82 C

ANISOU 122 CA SER A 336 2284 4572 4476 770 -446 -503 C

ATOM 123 CB SER A 336 54.095 16.434 -20.467 1.00 31.95 C

ANISOU 123 CB SER A 336 2316 5026 4798 861 -468 -597 C

ATOM 124 OG SER A 336 54.337 15.074 -20.142 1.00 33.68 O

ANISOU 124 OG SER A 336 2566 5243 4988 1088 -549 -616 O

ATOM 125 C SER A 336 51.901 15.920 -21.579 1.00 29.25 C

ANISOU 125 C SER A 336 2348 4417 4348 830 -360 -463 C

ATOM 126 O SER A 336 51.086 15.038 -21.269 1.00 29.76 O

ANISOU 126 O SER A 336 2585 4361 4362 927 -411 -428 O

ATOM 127 N SER A 337 52.166 16.233 -22.844 1.00 28.72 N

ANISOU 127 N SER A 337 2213 4414 4284 760 -226 -467 N

ATOM 128 CA SER A 337 51.555 15.491 -23.941 1.00 27.37 C

ANISOU 128 CA SER A 337 2163 4189 4047 811 -146 -447 C

ATOM 129 CB SER A 337 50.107 15.923 -24.208 1.00 25.82 C

ANISOU 129 CB SER A 337 2159 3849 3801 703 -126 -356 C

ATOM 130 OG SER A 337 49.993 17.233 -24.736 1.00 25.02 O

ANISOU 130 OG SER A 337 2022 3769 3717 524 -47 -301 O

ATOM 131 C SER A 337 52.380 15.600 -25.197 1.00 28.77 C

ANISOU 131 C SER A 337 2201 4511 4219 786 -9 -489 C

ATOM 132 O SER A 337 53.165 16.538 -25.354 1.00 29.57 O

ANISOU 132 O SER A 337 2138 4728 4370 66.

48. 499 O

ATOM 133 N ILE A 338 52.232 14.601 -26.062 1.00 28.60 N

ANISOU 133 N ILE A 338 2243 4486 4138 89.

46. 524 N

ATOM 134 CA ILE A 338 52.744 14.661 -27.433 1.00 29.37 C

ANISOU 134 CA ILE A 338 2253 4715 4191 862 197 -558 C

ATOM 135 CB ILE A 338 53.684 13.470 -27.745 1.00 30.62 C

ANISOU 135 CB ILE A 338 2306 4969 4358 1060 220 -684 C

ATOM 136 CG1 ILE A 338 52.951 12.126 -27.567 1.00 28.62 C

ANISOU 136 CG1 ILE A 338 2242 4558 4076 1227 144 -711 C

ATOM 137 CD1 ILE A 338 53.801 10.890 -27.901 1.00 31.84 C

ANISOU 137 CD1 ILE A 338 2573 5023 4504 1443 164 -841 C

ATOM 138 CG2 ILE A 338 54.936 13.557 -26.869 1.00 29.51 C

ANISOU 138 CG2 ILE A 338 1946 4947 4320 1128 157 -748 C

ATOM 139 C ILE A 338 51.544 14.715 -28.383 1.00 29.43 C

ANISOU 139 C ILE A 338 2448 4638 4097 787 257 -490 C

ATOM 140 O ILE A 338 50.421 14.456 -27.965 1.00 27.50 O

ANISOU 140 O ILE A 338 2379 4237 3831 796 177 -443 O

ATOM 141 N LYS A 339 51.768 15.077 -29.643 1.00 32.18 N

ANISOU 141 N LYS A 339 2753 5101 4374 708 395 -484 N

ATOM 142 CA LYS A 339 50.659 15.264 -30.588 1.00 32.96 C

ANISOU 142 CA LYS A 339 3017 5146 4361 628 443 -410 C

ATOM 143 CB LYS A 339 50.689 16.636 -31.277 1.00 33.66 C

ANISOU 143 CB LYS A 339 3068 5303 4417 436 542 -299 C

ATOM 144 CG LYS A 339 50.626 17.879 -30.433 1.00 35.13 C

ANISOU 144 CG LYS A 339 3225 5418 4704 302 495 -209 C

ATOM 145 CD LYS A 339 50.839 19.070 -31.356 1.00 39.41 C

ANISOU 145 CD LYS A 339 3730 6034 5211 126 622 -105 C

ATOM 146 CE LYS A 339 51.214 20.330 -30.602 1.00 43.35 C

ANISOU 146 CE LYS A 339 4145 6489 5837 -18 608 -49 C

ATOM 147 NZ LYS A 339 51.747 21.354 -31.562 1.00 47.40 N

ANISOU 147 NZ LYS A 339 4590 7093 6327 -188 758 41 N

ATOM 148 C LYS A 339 50.829 14.249 -31.693 1.00 34.82 C

ANISOU 148 C LYS A 339 3269 5464 4496 730 526 -506 C

ATOM 149 O LYS A 339 51.942 13.867 -32.033 1.00 35.45 O

ANISOU 149 O LYS A 339 3198 5686 4586 804 603 -605 O

ATOM 150 N ARG A 340 49.708 13.859 -32.287 1.00 34.88 N

ANISOU 150 N ARG A 340 3453 5392 4405 727 514 -488 N

ATOM 151 CA ARG A 340 49.725 12.999 -33.446 1.00 37.31 C

ANISOU 151 CA ARG A 340 3799 5779 4597 798 594 -585 C

ATOM 152 CB ARG A 340 49.722 11.545 -32.981 1.00 37.81 C

ANISOU 152 CB ARG A 340 3918 5738 4710 985 522 -715 C

ATOM 153 CG ARG A 340 49.740 10.518 -34.090 1.00 41.11 C

ANISOU 153 CG ARG A 340 4385 6209 5025 1077 596 -851 C

ATOM 154 CD ARG A 340 49.106 9.264 -33.574 1.00 44.08 C

ANISOU 154 CD ARG A 340 4906 6391 5449 1202 493 -927 C

ATOM 155 NE ARG A 340 49.351 8.129 -34.448 1.00 49.69 N

ANISOU 155 NE ARG A 340 5647 7130 6103 1325 557 -1096 N

ATOM 156 CZ ARG A 340 48.735 6.956 -34.322 1.00 52.03 C

ANISOU 156 CZ ARG A 340 6093 7254 6423 1418 492 -1183 C

ATOM 157 NH1 ARG A 340 47.836 6.774 -33.353 1.00 51.49 N

ANISOU 157 NH1 ARG A 340 6152 6986 6426 1395 368 -1102 N

ATOM 158 NH2 ARG A 340 49.013 5.967 -35.163 1.00 53.54 N

ANISOU 158 NH2 ARG A 340 6308 7469 6565 1528 558 -1356 N

ATOM 159 C ARG A 340 48.494 13.280 -34.318 1.00 36.74 C

ANISOU 159 C ARG A 340 3889 5680 4391 701 601 -510 C

ATOM 160 O ARG A 340 47.381 13.418 -33.808 1.00 35.04 O

ANISOU 160 O ARG A 340 3799 5317 4196 663 499 -439 O

ATOM 161 N GLU A 341 48.689 13.298 -35.631 1.00 38.65 N

ANISOU 161 N GLU A 341 4121 6076 4488 670 720 -537 N

ATOM 162 CA GLU A 341 47.613 13.581 -36.585 1.00 38.96 C

ANISOU 162 CA GLU A 341 4300 6129 4373 584 724 -467 C

ATOM 163 CB GLU A 341 48.207 14.150 -37.884 1.00 41.11 C

ANISOU 163 CB GLU A 341 4510 6619 4490 505 881 -436 C

ATOM 164 CG GLU A 341 47.223 14.984 -38.717 1.00 44.93 C

ANISOU 164 CG GLU A 341 5114 7131 4828 380 878 -285 C

ATOM 165 CD GLU A 341 47.713 16.411 -38.966 1.00 50.98 C

ANISOU 165 CD GLU A 341 5809 7976 5584 232 968 -111 C

ATOM 166 OE1 GLU A 341 48.843 16.587 -39.478 1.00 53.24 O

ANISOU 166 OE1 GLU A 341 5969 8430 5831 202 1115 -135 O

ATOM 167 OE2 GLU A 341 46.961 17.362 -38.638 1.00 52.85 O

ANISOU 167 OE2 GLU A 341 6117 8101 5863 142 896 49 O

ATOM 168 C GLU A 341 46.793 12.331 -36.867 1.00 38.09 C

ANISOU 168 C GLU A 341 4327 5941 4204 678 662 -589 C

ATOM 169 O GLU A 341 47.339 11.310 -37.253 1.00 39.85 O

ANISOU 169 O GLU A 341 4528 6213 4402 792 712 -749 O

ATOM 170 N GLU A 342 45.486 12.415 -36.661 1.00 36.22 N

ANISOU 170 N GLU A 342 4225 5579 3958 630 556 -523 N

ATOM 171 CA GLU A 342 44.583 11.283 -36.867 1.00 35.81 C

ANISOU 171 CA GLU A 342 4305 5437 3866 688 488 -634 C

ATOM 172 CB GLU A 342 44.147 10.658 -35.531 1.00 34.01 C

ANISOU 172 CB GLU A 342 4129 4994 3799 747 372 -653 C

ATOM 173 CG GLU A 342 45.206 9.806 -34.803 1.00 36.13 C

ANISOU 173 CG GLU A 342 4330 5210 4188 889 381 -758 C

ATOM 174 CD GLU A 342 44.743 9.377 -33.407 1.00 35.59 C

ANISOU 174 CD GLU A 342 4326 4936 4262 929 264 -729 C

ATOM 175 OE1 GLU A 342 45.588 9.256 -32.489 1.00 36.85 O

ANISOU 175 OE1 GLU A 342 4407 5063 4532 1012 245 -731 O

ATOM 176 OE2 GLU A 342 43.515 9.182 -33.211 1.00 38.13 O

ANISOU 176 OE2 GLU A 342 4771 5140 4578 874 190 -700 O

ATOM 177 C GLU A 342 43.348 11.764 -37.613 1.00 34.67 C

ANISOU 177 C GLU A 342 4264 5320 3589 586 446 -553 C

ATOM 178 O GLU A 342 42.952 12.925 -37.477 1.00 33.00 O

ANISOU 178 O GLU A 342 4047 5109 3382 490 423 -388 O

ATOM 179 N GLU A 343 42.744 10.866 -38.396 1.00 34.97 N

ANISOU 179 N GLU A 343 4394 5378 3515 612 430 -675 N

ATOM 180 CA GLU A 343 41.458 11.149 -39.027 1.00 34.95 C

ANISOU 180 CA GLU A 343 4487 5398 3393 529 359 -621 C

ATOM 181 CB GLU A 343 41.400 10.673 -40.480 1.00 36.90 C

ANISOU 181 CB GLU A 343 4778 5818 3423 531 413 -733 C

ATOM 182 CG GLU A 343 42.297 11.448 -41.402 1.00 40.28 C

ANISOU 182 CG GLU A 343 5137 6463 3706 499 544 -666 C

ATOM 183 CD GLU A 343 42.120 11.051 -42.851 1.00 46.55 C

ANISOU 183 CD GLU A 343 5988 7449 4252 492 592 -767 C

ATOM 184 OE1 GLU A 343 42.201 9.829 -43.156 1.00 49.23 O

ANISOU 184 OE1 GLU A 343 6363 7781 4562 569 603 -985 O

ATOM 185 OE2 GLU A 343 41.906 11.965 -43.686 1.00 47.82 O

ANISOU 185 OE2 GLU A 343 6164 7764 4241 412 616 -627 O

ATOM 186 C GLU A 343 40.331 10.521 -38.238 1.00 33.33 C

ANISOU 186 C GLU A 343 4367 5004 3293 529 234 -656 C

ATOM 187 O GLU A 343 40.314 9.306 -37.987 1.00 33.83 O

ANISOU 187 O GLU A 343 4478 4963 3412 597 215 -808 O

ATOM 188 N VAL A 344 39.377 11.366 -37.868 1.00 31.66 N

ANISOU 188 N VAL A 344 4174 4745 3110 451 153 -512 N

ATOM 189 CA VAL A 344 38.220 10.946 -37.086 1.00 29.70 C

ANISOU 189 CA VAL A 344 3988 4336 2960 43.

43. 524 C

ATOM 190 CB VAL A 344 38.219 11.619 -35.676 1.00 27.60 C

ANISOU 190 CB VAL A 344 3682 3937 2866 42.

8. 403 C

ATOM 191 CG1 VAL A 344 39.536 11.354 -34.968 1.00 27.04 C

ANISOU 191 CG1 VAL A 344 3551 3828 2895 49.

68. 437 C

ATOM 192 CG2 VAL A 344 38.006 13.082 -35.781 1.00 26.27 C

ANISOU 192 CG2 VAL A 344 3472 3829 2680 35.

3. 231 C

ATOM 193 C VAL A 344 36.924 11.195 -37.880 1.00 29.93 C

ANISOU 193 C VAL A 344 4067 4436 2869 358 -34 -498 C

ATOM 194 O VAL A 344 36.926 11.910 -38.891 1.00 30.08 O

ANISOU 194 O VAL A 344 4076 4615 2736 327 -12 -427 O

ATOM 195 N LEU A 345 35.842 10.556 -37.454 1.00 29.10 N

ANISOU 195 N LEU A 345 4013 4220 2824 331 -122 -559 N

ATOM 196 CA LEU A 345 34.564 10.639 -38.170 1.00 29.46 C

ANISOU 196 CA LEU A 345 4088 4339 2767 267 -210 -564 C

ATOM 197 CB LEU A 345 34.148 9.271 -38.665 1.00 30.37 C

ANISOU 197 CB LEU A 345 4269 4435 2834 260 -234 -769 C

ATOM 198 CG LEU A 345 34.852 8.751 -39.913 1.00 33.75 C

ANISOU 198 CG LEU A 345 4723 5011 3089 297 -167 -900 C

ATOM 199 CD1 LEU A 345 35.036 7.242 -39.784 1.00 35.77 C

ANISOU 199 CD1 LEU A 345 5045 5139 3408 333 -149 -1117 C

ATOM 200 CD2 LEU A 345 34.081 9.105 -41.171 1.00 33.10 C

ANISOU 200 CD2 LEU A 345 4653 5125 2797 243 -226 -900 C

ATOM 201 C LEU A 345 33.486 11.170 -37.248 1.00 27.67 C

ANISOU 201 C LEU A 345 3841 4009 2661 219 -296 -463 C

ATOM 202 O LEU A 345 33.301 10.630 -36.166 1.00 27.33 O

ANISOU 202 O LEU A 345 3812 3808 2766 218 -308 -498 O

ATOM 203 N THR A 346 32.793 12.229 -37.663 1.00 27.06 N

ANISOU 203 N THR A 346 3734 4024 2522 186 -351 -335 N

ATOM 204 CA THR A 346 31.706 12.815 -36.857 1.00 25.51 C

ANISOU 204 CA THR A 346 3504 3749 2440 153 -431 -248 C

ATOM 205 CB THR A 346 31.306 14.244 -37.367 1.00 25.70 C

ANISOU 205 CB THR A 346 3492 3871 2401 152 -474 -71 C

ATOM 206 OG1 THR A 346 30.535 14.151 -38.575 1.00 27.06 O

ANISOU 206 OG1 THR A 346 3676 4199 2405 136 -550 -97 O

ATOM 207 CG2 THR A 346 32.515 15.135 -37.609 1.00 24.02 C

ANISOU 207 CG2 THR A 346 3273 3699 2154 177 -384 49 C

ATOM 208 C THR A 346 30.457 11.896 -36.816 1.00 26.38 C

ANISOU 208 C THR A 346 3628 3829 2568 101 -515 -371 C

ATOM 209 O THR A 346 30.402 10.882 -37.518 1.00 27.44 O

ANISOU 209 O THR A 346 3805 4004 261.

84. 521 -521 O

ATOM 210 N GLY A 347 29.450 12.255 -36.016 1.00 25.61 N

ANISOU 210 N GLY A 347 3486 3661 258.

68. 575 -320 N

ATOM 211 CA GLY A 347 28.142 11.586 -36.109 1.00 25.17 C

ANISOU 211 CA GLY A 347 3414 3613 2535 0 -659 -421 C

ATOM 212 C GLY A 347 27.442 11.653 -37.467 1.00 26.55 C

ANISOU 212 C GLY A 347 3572 3975 2541 -19 -747 -458 C

ATOM 213 O GLY A 347 26.559 10.833 -37.753 1.00 27.47 O

ANISOU 213 O GLY A 347 3681 4117 2641 -85 -811 -591 O

ATOM 214 N ASN A 348 27.812 12.630 -38.302 1.00 26.51 N

ANISOU 214 N ASN A 348 3561 4103 240.

31. 754 -337 N

ATOM 215 CA ASN A 348 27.340 12.690 -39.715 1.00 27.47 C

ANISOU 215 CA ASN A 348 3685 4430 232.

26. 835 -360 C

ATOM 216 CB ASN A 348 27.036 14.128 -40.155 1.00 27.65 C

ANISOU 216 CB ASN A 348 3670 4556 228.

75. 894 -155 C

ATOM 217 CG ASN A 348 25.936 14.197 -41.212 1.00 30.51 C

ANISOU 217 CG ASN A 348 3999 5108 248.

66. 1036 -172 C

ATOM 218 OD1 ASN A 348 25.056 13.330 -41.277 1.00 32.90 O

ANISOU 218 OD1 ASN A 348 4267 5438 279.

8. 1112 -331 O

ATOM 219 ND2 ASN A 348 26.001 15.206 -42.070 1.00 30.49 N

ANISOU 219 ND2 ASN A 348 4008 5240 2337 120 -1076 -9 N

ATOM 220 C ASN A 348 28.300 12.039 -40.715 1.00 28.41 C

ANISOU 220 C ASN A 348 3879 4646 227.

37. 769 -462 C

ATOM 221 O ASN A 348 28.092 12.120 -41.927 1.00 29.94 O

ANISOU 221 O ASN A 348 4087 5027 2260.

37. 821 -478 O

ATOM 222 N LEU A 349 29.339 11.376 -40.203 1.00 27.99 N

ANISOU 222 N LEU A 349 3869 4473 229.

53. 657 -538 N

ATOM 223 CA LEU A 349 30.311 10.650 -41.043 1.00 29.00 C

ANISOU 223 CA LEU A 349 4058 4676 228.

77. 577 -664 C

ATOM 224 CB LEU A 349 29.602 9.567 -41.884 1.00 30.71 C

ANISOU 224 CB LEU A 349 4309 4973 238.

27. 646 -875 C

ATOM 225 CG LEU A 349 28.751 8.531 -41.136 1.00 30.08 C

ANISOU 225 CG LEU A 349 4234 4731 2466 -42 -696 -1020 C

ATOM 226 CD1 LEU A 349 28.022 7.598 -42.085 1.00 30.19 C

ANISOU 226 CD1 LEU A 349 4274 4842 2357 -109 -773 -1229 C

ATOM 227 CD2 LEU A 349 29.637 7.731 -40.222 1.00 29.27 C

ANISOU 227 CD2 LEU A 349 4181 4417 2521 -593 -1087 C

ATOM 228 C LEU A 349 31.195 11.574 -41.914 1.00 29.53 C

ANISOU 228 C LEU A 349 4130 4907 2185 121 -512 -535 C

ATOM 229 O LEU A 349 31.589 11.202 -43.025 1.00 31.24 O

ANISOU 229 O LEU A 349 4386 5279 2206 128 -480 -624 O

ATOM 230 N GLN A 350 31.500 12.768 -41.395 1.00 28.82 N

ANISOU 230 N GLN A 350 4003 4776 2171 141 -485 -330 N

ATOM 231 CA GLN A 350 32.430 13.729 -42.020 1.00 30.27 C

ANISOU 231 CA GLN A 350 4189 5072 2238 164 -402 -180 C

ATOM 232 CB GLN A 350 31.967 15.164 -41.722 1.00 29.66 C

ANISOU 232 CB GLN A 350 4082 4968 2219 164 -454 54 C

ATOM 233 CG GLN A 350 32.811 16.292 -42.325 1.00 30.58 C

ANISOU 233 CG GLN A 350 4211 5174 2234 167 -373 242 C

ATOM 234 CD GLN A 350 32.356 17.682 -41.883 1.00 30.94 C

ANISOU 234 CD GLN A 350 4238 5137 2382 172 -423 464 C

ATOM 235 OE1 GLN A 350 31.407 17.830 -41.095 1.00 28.70 O

ANISOU 235 OE1 GLN A 350 3920 4739 2246 182 -518 470 O

ATOM 236 NE2 GLN A 350 33.032 18.708 -42.394 1.00 31.65 N

ANISOU 236 NE2 GLN A 350 4350 5278 2397 161 -353 643 N

ATOM 237 C GLN A 350 33.826 13.515 -41.457 1.00 29.30 C

ANISOU 237 C GLN A 350 4053 4868 2210 193 -262 -209 C

ATOM 238 O GLN A 350 33.975 13.375 -40.257 1.00 27.88 O

ANISOU 238 O GLN A 350 3848 4515 2231 203 -253 -217 O

ATOM 239 N THR A 351 34.832 13.499 -42.315 1.00 30.89 N

ANISOU 239 N THR A 351 4265 5208 2262 207 -156 -226 N

ATOM 240 CA THR A 351 36.226 13.364 -41.880 1.00 31.43 C

ANISOU 240 CA THR A 351 4295 5233 2412 241 -21 -254 C

ATOM 241 CB THR A 351 37.120 12.811 -43.019 1.00 33.11 C

ANISOU 241 CB THR A 351 4522 5629 2431 26.

91. 373 C

ATOM 242 OG1 THR A 351 36.598 11.543 -43.428 1.00 32.96 O

ANISOU 242 OG1 THR A 351 4555 5620 2346 28.

42. 592 O

ATOM 243 CG2 THR A 351 38.567 12.622 -42.553 1.00 34.11 C

ANISOU 243 CG2 THR A 351 4582 5723 2657 309 229 -418 C

ATOM 244 C THR A 351 36.792 14.669 -41.370 1.00 31.33 C

ANISOU 244 C THR A 351 4233 5181 2492 22.

30. 48 C

ATOM 245 O THR A 351 36.719 15.702 -42.065 1.00 32.56 O

ANISOU 245 O THR A 351 4400 5442 2531 184 38 119 O

ATOM 246 N LEU A 352 37.338 14.623 -40.153 1.00 30.61 N

ANISOU 246 N LEU A 352 4091 4933 2605 24.

57. 57 N

ATOM 247 CA LEU A 352 38.103 15.732 -39.588 1.00 30.88 C

ANISOU 247 CA LEU A 352 4065 4923 2744 215 120 94 C

ATOM 248 CB LEU A 352 37.467 16.248 -38.296 1.00 28.81 C

ANISOU 248 CB LEU A 352 3790 4476 2680 205 35 169 C

ATOM 249 CG LEU A 352 36.033 16.805 -38.295 1.00 28.66 C

ANISOU 249 CG LEU A 352 3809 4417 2663 183 -86 262 C

ATOM 250 CD1 LEU A 352 35.625 17.143 -36.864 1.00 26.74 C

ANISOU 250 CD1 LEU A 352 3538 3992 2629 184 -138 291 C

ATOM 251 CD2 LEU A 352 35.847 18.027 -39.226 1.00 29.78 C

ANISOU 251 CD2 LEU A 352 3972 4656 2686 149 -86 449 C

ATOM 252 C LEU A 352 39.550 15.297 -39.350 1.00 32.06 C

ANISOU 252 C LEU A 352 4145 5094 2942 250 241 5 C

ATOM 253 O LEU A 352 39.807 14.219 -38.805 1.00 31.91 O

ANISOU 253 O LEU A 352 4119 5002 3003 313 237 -151 O

ATOM 254 N LYS A 353 40.489 16.127 -39.790 1.00 33.85 N

ANISOU 254 N LYS A 353 4320 5423 3120 208 350 105 N

ATOM 255 CA LYS A 353 41.898 15.963 -39.470 1.00 34.96 C

ANISOU 255 CA LYS A 353 4358 5594 3332 230 465 43 C

ATOM 256 CB LYS A 353 42.735 16.484 -40.626 1.00 37.50 C

ANISOU 256 CB LYS A 353 4644 6115 3488 179 606 104 C

ATOM 257 CG LYS A 353 44.133 15.905 -40.717 1.00 41.91 C

ANISOU 257 CG LYS A 353 5091 6777 4055 224 740 -29 C

ATOM 258 CD LYS A 353 44.876 16.499 -41.917 1.00 48.11 C

ANISOU 258 CD LYS A 353 5841 7780 4658 151 894 45 C

ATOM 259 CE LYS A 353 45.805 15.477 -42.553 1.00 51.72 C

ANISOU 259 CE LYS A 353 6232 8401 5018 228 1016 -154 C

ATOM 260 NZ LYS A 353 46.301 15.930 -43.897 1.00 55.83 N

ANISOU 260 NZ LYS A 353 6745 9164 5305 155 1168 -93 N

ATOM 261 C LYS A 353 42.176 16.775 -38.212 1.00 33.47 C

ANISOU 261 C LYS A 353 4107 5260 3349 199 442 138 C

ATOM 262 O LYS A 353 42.115 18.008 -38.238 1.00 33.44 O

ANISOU 262 O LYS A 353 4099 5242 3365 118 453 305 O

ATOM 263 N ILE A 354 42.447 16.075 -37.110 1.00 32.36 N

ANISOU 263 N ILE A 354 3930 5007 3360 266 404 30 N

ATOM 264 CA ILE A 354 42.806 16.720 -35.842 1.00 31.37 C

ANISOU 264 CA ILE A 354 3738 4762 3418 245 377 87 C

ATOM 265 CB ILE A 354 41.737 16.490 -34.731 1.00 29.39 C

ANISOU 265 CB ILE A 354 3552 4334 3280 270 247 81 C

ATOM 266 CG1 ILE A 354 41.620 15.001 -34.379 1.00 28.30 C

ANISOU 266 CG1 ILE A 354 3451 4143 3159 368 206 -78 C

ATOM 267 CD1 ILE A 354 40.879 14.705 -33.055 1.00 28.35 C

ANISOU 267 CD1 ILE A 354 3501 3978 3294 389 104 -86 C

ATOM 268 CG2 ILE A 354 40.373 17.085 -35.158 1.00 29.30 C

ANISOU 268 CG2 ILE A 354 3629 4293 3209 219 176 185 C

ATOM 269 C ILE A 354 44.170 16.257 -35.328 1.00 31.76 C

ANISOU 269 C ILE A 354 3668 4847 3552 301 442 -15 C

ATOM 270 O ILE A 354 44.603 15.135 -35.611 1.00 32.13 O

ANISOU 270 O ILE A 354 3703 4946 3559 394 471 -157 O

ATOM 271 N ARG A 355 44.834 17.127 -34.571 1.00 31.99 N

ANISOU 271 N ARG A 355 3606 4847 3703 249 457 49 N

ATOM 272 CA ARG A 355 46.027 16.753 -33.847 1.00 32.46 C

ANISOU 272 CA ARG A 355 3536 4929 3866 306 483 -44 C

ATOM 273 CB ARG A 355 46.987 17.948 -33.720 1.00 34.26 C

ANISOU 273 CB ARG A 355 3637 5219 4163 198 559 35 C

ATOM 274 CG ARG A 355 47.656 18.288 -35.032 1.00 39.00 C

ANISOU 274 CG ARG A 355 4181 5997 4639 132 708 67 C

ATOM 275 CD ARG A 355 48.600 19.431 -34.872 1.00 45.77 C

ANISOU 275 CD ARG A 355 4910 6902 5578 6 790 144 C

ATOM 276 NE ARG A 355 48.574 20.333 -36.023 1.00 52.25 N

ANISOU 276 NE ARG A 355 5764 7806 6284 -123 901 284 N

ATOM 277 CZ ARG A 355 49.146 21.539 -36.057 1.00 56.14 C

ANISOU 277 CZ ARG A 355 6188 8307 6837 -272 980 398 C

ATOM 278 NH1 ARG A 355 49.801 22.023 -34.996 1.00 55.45 N

ANISOU 278 NH1 ARG A 355 5982 8157 6928 -320 956 369 N

ATOM 279 NH2 ARG A 355 49.061 22.269 -37.166 1.00 58.73 N

ANISOU 279 NH2 ARG A 355 6571 8703 7040 -381 1083 542 N

ATOM 280 C ARG A 355 45.608 16.213 -32.488 1.00 29.93 C

ANISOU 280 C ARG A 355 3252 4453 3666 379 359 -91 C

ATOM 281 O ARG A 355 45.187 16.959 -31.616 1.00 28.02 O

ANISOU 281 O ARG A 355 3025 4108 3513 324 295 -17 O

ATOM 282 N VAL A 356 45.705 14.897 -32.339 1.00 28.99 N

ANISOU 282 N VAL A 356 3158 4313 3543 504 331 -216 N

ATOM 283 CA VAL A 356 45.350 14.233 -31.098 1.00 27.31 C

ANISOU 283 CA VAL A 356 2994 3955 3426 581 223 -254 C

ATOM 284 CB VAL A 356 45.003 12.746 -31.341 1.00 27.54 C

ANISOU 284 CB VAL A 356 3118 3930 3417 695 198 -368 C

ATOM 285 CG1 VAL A 356 44.842 11.989 -30.014 1.00 27.23 C

ANISOU 285 CG1 VAL A 356 3128 3741 3479 78.

99. 394 C

ATOM 286 CG2 VAL A 356 43.732 12.634 -32.157 1.00 26.35 C

ANISOU 286 CG2 VAL A 356 3094 3753 3164 637 186 -350 C

ATOM 287 C VAL A 356 46.460 14.367 -30.058 1.00 26.67 C

ANISOU 287 C VAL A 356 2786 3889 3460 624 204 -279 C

ATOM 288 O VAL A 356 47.604 14.038 -30.324 1.00 28.57 O

ANISOU 288 O VAL A 356 2907 4239 3708 689 263 -354 O

ATOM 289 N HIS A 357 46.128 14.879 -28.884 1.00 25.43 N

ANISOU 289 N HIS A 357 2642 3635 3385 590 121 -224 N

ATOM 290 CA HIS A 357 47.107 14.993 -27.808 1.00 25.05 C

ANISOU 290 CA HIS A 357 2478 3607 3433 63.

79. 254 C

ATOM 291 CB HIS A 357 46.849 16.229 -26.954 1.00 23.90 C

ANISOU 291 CB HIS A 357 2315 3412 3353 51.

36. 177 C

ATOM 292 CG HIS A 357 47.266 17.509 -27.615 1.00 24.64 C

ANISOU 292 CG HIS A 357 2322 3585 3457 380 123 -117 C

ATOM 293 ND1 HIS A 357 48.390 18.216 -27.235 1.00 25.54 N

ANISOU 293 ND1 HIS A 357 2277 3779 3648 325 146 -136 N

ATOM 294 CE1 HIS A 357 48.507 19.290 -27.995 1.00 24.49 C

ANISOU 294 CE1 HIS A 357 2110 3684 3511 188 235 -62 C

ATOM 295 NE2 HIS A 357 47.505 19.300 -28.857 1.00 25.00 N

ANISOU 295 NE2 HIS A 357 2307 3703 3488 167 263 9 N

ATOM 296 CD2 HIS A 357 46.725 18.191 -28.652 1.00 22.30 C

ANISOU 296 CD2 HIS A 357 2077 3296 3100 282 192 -34 C

ATOM 297 C HIS A 357 47.122 13.716 -26.984 1.00 25.08 C

ANISOU 297 C HIS A 357 2536 3529 3463 781 -5 -319 C

ATOM 298 O HIS A 357 46.079 13.215 -26.573 1.00 24.14 O

ANISOU 298 O HIS A 357 2561 3280 3330 795 -66 -297 O

ATOM 299 N GLU A 358 48.322 13.175 -26.778 1.00 25.97 N

ANISOU 299 N GLU A 358 2530 3722 3616 895 -6 -397 N

ATOM 300 CA GLU A 358 48.492 11.913 -26.065 1.00 25.43 C

ANISOU 300 CA GLU A 358 2512 3575 3577 1062 -86 -451 C

ATOM 301 CB GLU A 358 49.224 10.905 -26.939 1.00 26.70 C

ANISOU 301 CB GLU A 358 2626 3796 3722 1198 -23 -558 C

ATOM 302 CG GLU A 358 48.506 10.641 -28.264 1.00 26.20 C

ANISOU 302 CG GLU A 358 2661 3726 3567 115.

64. 583 C

ATOM 303 CD GLU A 358 49.340 9.852 -29.243 1.00 28.06 C

ANISOU 303 CD GLU A 358 2826 4059 3777 1267 151 -709 C

ATOM 304 OE1 GLU A 358 50.595 9.994 -29.261 1.00 27.40 O

ANISOU 304 OE1 GLU A 358 2558 4117 3735 1329 192 -763 O

ATOM 305 OE2 GLU A 358 48.730 9.082 -30.014 1.00 28.42 O

ANISOU 305 OE2 GLU A 358 2993 4046 3760 1295 181 -767 O

ATOM 306 C GLU A 358 49.233 12.107 -24.751 1.00 25.42 C

ANISOU 306 C GLU A 358 2416 3596 3646 1113 -180 -446 C

ATOM 307 O GLU A 358 50.317 12.638 -24.734 1.00 25.81 O

ANISOU 307 O GLU A 358 2285 3785 3737 1107 -159 -481 O

ATOM 308 N GLY A 359 48.608 11.697 -23.651 1.00 24.36 N

ANISOU 308 N GLY A 359 2405 3335 3518 1152 -283 -403 N

ATOM 309 CA GLY A 359 49.203 11.836 -22.335 1.00 23.73 C

ANISOU 309 CA GLY A 359 2258 3280 3476 1204 -388 -394 C

ATOM 310 C GLY A 359 48.271 12.445 -21.311 1.00 22.21 C

ANISOU 310 C GLY A 359 2168 3005 3267 1103 -452 -318 C

ATOM 311 O GLY A 359 47.324 13.163 -21.653 1.00 21.39 O

ANISOU 311 O GLY A 359 2131 2854 3144 965 -404 -274 O

ATOM 312 N TYR A 360 48.535 12.139 -20.049 1.00 22.42 N

ANISOU 312 N TYR A 360 2206 3018 3293 1183 -562 -305 N

ATOM 313 CA TYR A 360 47.836 12.761 -18.939 1.00 22.10 C

ANISOU 313 CA TYR A 360 2238 2934 3226 1096 -623 -252 C

ATOM 314 CB TYR A 360 48.072 11.966 -17.646 1.00 23.09 C

ANISOU 314 CB TYR A 360 2423 3034 3318 1228 -745 -227 C

ATOM 315 CG TYR A 360 47.620 12.724 -16.422 1.00 22.63 C

ANISOU 315 CG TYR A 360 2399 2981 3217 1141 -809 -196 C

ATOM 316 CD1 TYR A 360 46.261 12.802 -16.094 1.00 21.89 C

ANISOU 316 CD1 TYR A 360 2469 2771 3076 1053 -784 -137 C

ATOM 317 CE1 TYR A 360 45.826 13.516 -14.980 1.00 22.60 C

ANISOU 317 CE1 TYR A 360 2589 2877 3121 976 -829 -125 C

ATOM 318 CZ TYR A 360 46.759 14.181 -14.201 1.00 23.69 C

ANISOU 318 CZ TYR A 360 2599 3145 3259 979 -908 -177 C

ATOM 319 OH TYR A 360 46.326 14.889 -13.103 1.00 24.72 O

ANISOU 319 OH TYR A 360 2764 3296 3335 903 -950 -184 O

ATOM 320 CE2 TYR A 360 48.122 14.118 -14.506 1.00 23.39 C

ANISOU 320 CE2 TYR A 360 2391 3226 3272 1057 -943 -234 C

ATOM 321 CD2 TYR A 360 48.543 13.397 -15.617 1.00 21.33 C

ANISOU 321 CD2 TYR A 360 2094 2952 3059 1140 -889 -241 C

ATOM 322 C TYR A 360 48.232 14.229 -18.731 1.00 21.86 C

ANISOU 322 C TYR A 360 2068 3007 3231 959 -615 -276 C

ATOM 323 O TYR A 360 49.413 14.553 -18.673 1.00 23.34 O

ANISOU 323 O TYR A 360 2082 3326 3462 981 -634 -333 O

ATOM 324 N GLU A 361 47.237 15.100 -18.598 1.00 21.04 N

ANISOU 324 N GLU A 361 2037 2837 3118 821 -587 -239 N

ATOM 325 CA GLU A 361 47.450 16.524 -18.288 1.00 21.68 C

ANISOU 325 CA GLU A 361 2021 2973 3244 684 -582 -262 C

ATOM 326 CB GLU A 361 47.406 17.391 -19.552 1.00 20.98 C

ANISOU 326 CB GLU A 361 1876 2893 3201 564 -469 -250 C

ATOM 327 CG GLU A 361 48.599 17.217 -20.468 1.00 24.43 C

ANISOU 327 CG GLU A 361 2161 3450 3670 596 -412 -291 C

ATOM 328 CD GLU A 361 48.413 17.894 -21.813 1.00 22.96 C

ANISOU 328 CD GLU A 361 1960 3269 3496 484 -289 -254 C

ATOM 329 OE1 GLU A 361 47.351 17.715 -22.440 1.00 20.90 O

ANISOU 329 OE1 GLU A 361 1833 2919 3188 469 -249 -198 O

ATOM 330 OE2 GLU A 361 49.338 18.607 -22.238 1.00 26.07 O

ANISOU 330 OE2 GLU A 361 2204 3762 3940 408 -232 -278 O

ATOM 331 C GLU A 361 46.384 17.031 -17.332 1.00 20.41 C

ANISOU 331 C GLU A 361 1975 2727 3053 614 -618 -235 C

ATOM 332 O GLU A 361 45.240 16.587 -17.379 1.00 19.53 O

ANISOU 332 O GLU A 361 2009 2512 2900 617 -599 -184 O

ATOM 333 N GLU A 362 46.774 17.961 -16.476 1.00 21.16 N

ANISOU 333 N GLU A 362 1994 2876 3172 547 -666 -282 N

ATOM 334 CA GLU A 362 45.841 18.688 -15.628 1.00 22.46 C

ANISOU 334 CA GLU A 362 2243 2974 3317 465 -683 -283 C

ATOM 335 CB GLU A 362 46.105 18.430 -14.141 1.00 22.93 C

ANISOU 335 CB GLU A 362 2317 3092 3304 522 -796 -319 C

ATOM 336 CG GLU A 362 45.054 19.016 -13.191 1.00 23.73 C

ANISOU 336 CG GLU A 362 2522 3135 3361 454 -803 -328 C

ATOM 337 CD GLU A 362 45.445 18.797 -11.736 1.00 26.51 C

ANISOU 337 CD GLU A 362 2881 3575 3616 507 -916 -369 C

ATOM 338 OE1 GLU A 362 44.878 17.909 -11.080 1.00 31.01 O

ANISOU 338 OE1 GLU A 362 3579 4121 4081 581 -946 -311 O

ATOM 339 OE2 GLU A 362 46.357 19.496 -11.254 1.00 32.87 O

ANISOU 339 OE2 GLU A 362 3562 4482 4446 471 -977 -458 O

ATOM 340 C GLU A 362 45.923 20.184 -15.927 1.00 22.18 C

ANISOU 340 C GLU A 362 2128 2929 3372 317 -633 -319 C

ATOM 341 O GLU A 362 47.018 20.735 -16.087 1.00 23.04 O

ANISOU 341 O GLU A 362 2089 3123 3544 271 -636 -371 O

ATOM 342 N PHE A 363 44.759 20.825 -15.996 1.00 21.18 N

ANISOU 342 N PHE A 363 2095 2693 3259 243 -588 -290 N

ATOM 343 CA PHE A 363 44.646 22.260 -16.286 1.00 21.78 C

ANISOU 343 CA PHE A 363 2129 2714 3431 111 -538 -309 C

ATOM 344 CB PHE A 363 44.028 22.491 -17.691 1.00 20.64 C

ANISOU 344 CB PHE A 363 2025 2495 332.

74. 443 -220 C

ATOM 345 CG PHE A 363 44.832 21.911 -18.837 1.00 21.21 C

ANISOU 345 CG PHE A 363 2029 2642 3388 104 -397 -186 C

ATOM 346 CD1 PHE A 363 45.831 22.663 -19.453 1.00 20.96 C

ANISOU 346 CD1 PHE A 363 1874 2663 342.

19. 346 -195 C

ATOM 347 CE1 PHE A 363 46.570 22.150 -20.514 1.00 21.38 C

ANISOU 347 CE1 PHE A 363 1855 2803 346.

45. 287 -172 C

ATOM 348 CZ PHE A 363 46.313 20.885 -20.998 1.00 18.73 C

ANISOU 348 CZ PHE A 363 1579 2489 3048 163 -284 -150 C

ATOM 349 CE2 PHE A 363 45.316 20.123 -20.407 1.00 20.47 C

ANISOU 349 CE2 PHE A 363 1932 2638 3209 242 -340 -139 C ATOM 350 CD2 PHE A 363 44.570 20.637 -19.319 1.00 18.91 C ANISOU 350 CD2 PHE A 363 1799 2365 3021 209 -392 -151 C ATOM 351 C PHE A 363 43.738 22.994 -15.315 1.00 21.72 C ANISOU 351 C PHE A 363 2196 2632 3426.

65. 558 -349 C ATOM 352 O PHE A 363 42.737 22.439 -14.830 1.00 20.51 O ANISOU 352 O PHE A 363 2152 2441 3199 117 -569 -326 O ATOM 353 N THR A 364 44.060 24.266 -15.070 1.00 22.89 N ANISOU 353 N THR A 364 2282 2752 3664 -41 -553 -414 N ATOM 354 CA THR A 364 43.032 25.177 -14.615 1.00 23.63 C ANISOU 354 CA THR A 364 2449 2733 3796 -93 -534 -443 C ATOM 355 CB THR A 364 43.500 26.176 -13.539 1.00 25.43 C ANISOU 355 CB THR A 364 2624 2968 4069 -171 -580 -577 C ATOM 356 OG1 THR A 364 44.450 27.087 -14.102 1.00 29.67 O ANISOU 356 OG1 THR A 364 3054 3489 4730 -281 -554 -601 O ATOM 357 CG2 THR A 364 44.117 25.466 -12.315 1.00 24.74 C ANISOU 357 CG2 THR A 364 2509 3025 3866 -111 -682 -657 C ATOM 358 C THR A 364 42.480 25.903 -15.855 1.00 23.68 C ANISOU 358 C THR A 364 2479 2620 3896 -148 -448 -357 C ATOM 359 O THR A 364 43.224 26.192 -16.803 1.00 23.87 O ANISOU 359 O THR A 364 2436 2655 3980 -201 -406 -313 O ATOM 360 N MSE A 365 41.172 26.145 -15.860 1.00 22.96 N ANISOU 360 N MSE A 365 2483 2430 3811 -130 -423 -327 N ATOM 361 CA MSE A 365 40.493 26.940 -16.879 1.00 23.90 C ANISOU 361 CA MSE A 365 2637 2429 4017 -165 -361 -246 C ATOM 362 CB MSE A 365 39.333 26.162 -17.525 1.00 22.98 C ANISOU 362 CB MSE A 365 2597 2301 3833 -88 -343 -155 C ATOM 363 CG MSE A 365 39.696 24.837 -18.242 1.00 23.11 C ANISOU 363 CG MSE A 365 2611 2416 3753 -32 -341 -95 C ATOM 364 SE MSE A 365 38.160 23.718 -18.667 0.90 26.48 SE ANISOU 364 SE MSE A 365 3137 2833 409.

49. 336 -31 SE ATOM 365 CE MSE A 365 37.026 25.011 -19.510 1.00 21.85 C ANISOU 365 CE MSE A 365 2574 2128 3599.

18. 301 38 C ATOM 366 C MSE A 365 39.916 28.149 -16.156 1.00 23.45 C ANISOU 366 C MSE A 365 2605 2254 4051 -209 -361 -322 C ATOM 367 O MSE A 365 39.223 27.994 -15.148 1.00 23.44 O ANISOU 367 O MSE A 365 2645 2258 4002 -167 -386 -396 O ATOM 368 N VAL A 366 40.215 29.346 -16.654 1.00 23.42 N ANISOU 368 N VAL A 366 2581 2139 4177 -293 -326 -306 N ATOM 369 CA VAL A 366 39.691 30.586 -16.090 1.00 23.54 C ANISOU 369 CA VAL A 366 2629 2009 4308 -331 -319 -382 C ATOM 370 CB VAL A 366 40.833 31.452 -15.443 1.00 25.39 C ANISOU 370 CB VAL A 366 2793 2224 4631 -448 -336 -505 C ATOM 371 CG1 VAL A 366 40.312 32.803 -14.943 1.00 25.44 C ANISOU 371 CG1 VAL A 366 2842 2047 4776 -492 -323 -594 C ATOM 372 CG2 VAL A 366 41.533 30.678 -14.298 1.00 25.91 C ANISOU 372 CG2 VAL A 366 2801 2461 4582 -433 -406 -628 C ATOM 373 C VAL A 366 38.916 31.393 -17.163 1.00 24.02 C ANISOU 373 C VAL A 366 2745 1911 4469 -329 -270 -260 C ATOM 374 O VAL A 366 39.498 31.895 -18.140 1.00 24.09 O ANISOU 374 O VAL A 366 2741 1868 4545 -398 -232 -164 O ATOM 375 N GLY A 367 37.609 31.524 -16.962 1.00 23.61 N ANISOU 375 N GLY A 367 2753 1792 4425 -248 -271 -262 N ATOM 376 CA GLY A 367 36.782 32.410 -17.779 1.00 25.53 C ANISOU 376 CA GLY A 367 3047 1876 4776 -223 -244 -164 C ATOM 377 C GLY A 367 36.277 33.660 -17.044 1.00 27.40 C ANISOU 377 C GLY A 367 3313 1940 5157 -225 -240 -269 C ATOM 378 O GLY A 367 36.620 33.896 -15.876 1.00 28.05 O ANISOU 378 O GLY A 367 3375 2032 5251 -261 -254 -435 O ATOM 379 N LYS A 368 35.459 34.461 -17.728 1.00 28.02 N ANISOU 379 N LYS A 368 3442 1863 5342 -177 -225 -178 N ATOM 380 CA LYS A 368 34.815 35.621 -17.111 1.00 30.01 C ANISOU 380 CA LYS A 368 3727 1931 5744 -146 -219 -276 C ATOM 381 CB LYS A 368 34.065 36.473 -18.152 1.00 31.76 C

ANISOU 381 CB LYS A 368 4007 1974 6086 -83 -211 -125 C

ATOM 382 CG LYS A 368 34.947 37.212 -19.147 1.00 36.76 C

ANISOU 382 CG LYS A 368 4677 2481 6808 -185 -185 20 C

ATOM 383 CD LYS A 368 34.052 37.959 -20.123 1.00 43.28 C

ANISOU 383 CD LYS A 368 5574 3141 7729 -94 -190 186 C

ATOM 384 CE LYS A 368 34.692 38.098 -21.504 1.00 48.10 C

ANISOU 384 CE LYS A 368 6224 3733 8319 -165 -165 410 C

ATOM 385 NZ LYS A 368 33.990 39.150 -22.301 1.00 50.85 N

ANISOU 385 NZ LYS A 368 6662 3864 8792 -92 -174 569 N

ATOM 386 C LYS A 368 33.837 35.243 -15.977 1.00 28.59 C

ANISOU 386 C LYS A 368 3533 1823 5507 -54 -230 -427 C

ATOM 387 O LYS A 368 33.803 35.912 -14.963 1.00 28.78 O

ANISOU 387 O LYS A 368 3561 1774 5601 -66 -224 -594 O

ATOM 388 N ARG A 369 33.047 34.184 -16.141 1.00 26.59 N

ANISOU 388 N ARG A 369 3264 1712 5126 28 -239 -377 N

ATOM 389 CA ARG A 369 32.032 33.851 -15.117 1.00 25.86 C

ANISOU 389 CA ARG A 369 3155 1690 4982 105 -231 -507 C

ATOM 390 CB ARG A 369 30.615 34.105 -15.636 1.00 26.07 C

ANISOU 390 CB ARG A 369 3177 1657 5072 225 -227 -447 C

ATOM 391 CG ARG A 369 30.370 35.495 -16.189 1.00 28.17 C

ANISOU 391 CG ARG A 369 3477 1696 5532 264 -228 -403 C

ATOM 392 CD ARG A 369 28.865 35.741 -16.363 1.00 30.60 C

ANISOU 392 CD ARG A 369 3757 1968 5902 411 -232 -393 C

ATOM 393 NE ARG A 369 28.465 36.887 -15.535 1.00 37.04 N

ANISOU 393 NE ARG A 369 4580 2621 6871 463 -207 -550 N

ATOM 394 CZ ARG A 369 27.527 36.892 -14.591 1.00 37.12 C

ANISOU 394 CZ ARG A 369 4542 2678 6882 543 -176 -709 C

ATOM 395 NH1 ARG A 369 26.793 35.818 -14.317 1.00 34.10 N

ANISOU 395 NH1 ARG A 369 4097 2499 6360 575 -163 -727 N

ATOM 396 NH2 ARG A 369 27.296 38.024 -13.941 1.00 43.52 N

ANISOU 396 NH2 ARG A 369 5369 3322 7847 590 -151 -856 N

ATOM 397 C ARG A 369 32.135 32.449 -14.526 1.00 23.85 C

ANISOU 397 C ARG A 369 2878 1646 4537 96 -238 -539 C

ATOM 398 O ARG A 369 31.300 32.046 -13.716 1.00 22.65 O

ANISOU 398 O ARG A 369 2714 1571 4319 145 -220 -626 O

ATOM 399 N ALA A 370 33.158 31.705 -14.934 1.00 23.31 N

ANISOU 399 N ALA A 370 2805 1669 4383 35 -258 -466 N

ATOM 400 CA ALA A 370 33.390 30.376 -14.395 1.00 22.66 C

ANISOU 400 CA ALA A 370 2715 1763 4132 32 -271 -485 C

ATOM 401 CB ALA A 370 32.551 29.299 -15.160 1.00 21.26 C

ANISOU 401 CB ALA A 370 2543 1663 3872 89 -268 -369 C

ATOM 402 C ALA A 370 34.875 30.034 -14.427 1.00 22.52 C

ANISOU 402 C ALA A 370 2679 1811 4069 -42 -299 -476 C

ATOM 403 O ALA A 370 35.619 30.550 -15.262 1.00 23.04 O

ANISOU 403 O ALA A 370 2730 1812 4213 -93 -297 -408 O

ATOM 404 N THR A 371 35.290 29.169 -13.503 1.00 22.37 N

ANISOU 404 N THR A 371 2656 1925 3920 -44 -324 -542 N

ATOM 405 CA THR A 371 36.622 28.573 -13.512 1.00 22.86 C

ANISOU 405 CA THR A 371 2686 2083 3918 -84 -362 -529 C

ATOM 406 CB THR A 371 37.577 29.196 -12.446 1.00 24.26 C

ANISOU 406 CB THR A 371 2826 2283 4108 -147 -400 -676 C

ATOM 407 OG1 THR A 371 37.179 28.782 -11.144 1.00 27.06 O

ANISOU 407 OG1 THR A 371 3210 2727 4343 -114 -419 -776 O

ATOM 408 CG2 THR A 371 37.597 30.704 -12.518 1.00 22.87 C

ANISOU 408 CG2 THR A 371 2640 1949 4099 -210 -377 -743 C

ATOM 409 C THR A 371 36.510 27.054 -13.335 1.00 21.90 C

ANISOU 409 C THR A 371 2588 2092 3640 -29 -380 -480 C

ATOM 410 O THR A 371 35.451 26.546 -12.967 1.00 22.77 O

ANISOU 410 O THR A 371 2742 2223 3688 15 -360 -478 O

ATOM 411 N ALA A 372 37.576 26.312 -13.616 1.00 21.17 N

ANISOU 411 N ALA A 372 2467 2082 3493 -32 -413 -439 N

ATOM 412 CA ALA A 372 37.495 24.865 -13.505 1.00 19.77 C

ANISOU 412 CA ALA A 372 2327 1997 3186 28 -430 -386 C

ATOM 413 CB ALA A 372 36.796 24.241 -14.737 1.00 18.33 C

ANISOU 413 CB ALA A 372 2174 1784 300.

59. 394 -271 C

ATOM 414 C ALA A 372 38.835 24.237 -13.308 1.00 19.97 C

ANISOU 414 C ALA A 372 2310 2121 315.

39. 484 -393 C

ATOM 415 O ALA A 372 39.853 24.849 -13.608 1.00 20.79 O

ANISOU 415 O ALA A 372 2337 2231 3330 -8 -497 -419 O

ATOM 416 N ILE A 373 38.816 23.010 -12.789 1.00 19.57 N

ANISOU 416 N ILE A 373 2308 2144 2983 102 -514 -368 N

ATOM 417 CA ILE A 373 39.963 22.112 -12.831 1.00 19.72 C

ANISOU 417 CA ILE A 373 2295 2249 2948 151 -568 -345 C

ATOM 418 CB ILE A 373 40.416 21.607 -11.444 1.00 20.88 C

ANISOU 418 CB ILE A 373 2464 2493 2978 193 -643 -394 C

ATOM 419 CG1 ILE A 373 40.502 22.762 -10.432 1.00 22.57 C

ANISOU 419 CG1 ILE A 373 2645 2729 3201 130 -667 -517 C

ATOM 420 CD1 ILE A 373 40.936 22.348 -8.989 1.00 22.21 C

ANISOU 420 CD1 ILE A 373 2624 2805 3011 169 -752 -574 C

ATOM 421 CG2 ILE A 373 41.764 20.932 -11.585 1.00 18.66 C

ANISOU 421 CG2 ILE A 373 2115 2300 2676 252 -710 -381 C

ATOM 422 C ILE A 373 39.645 20.919 -13.691 1.00 18.62 C

ANISOU 422 C ILE A 373 2207 2092 2774 209 -544 -246 C

ATOM 423 O ILE A 373 38.635 20.253 -13.476 1.00 18.19 O

ANISOU 423 O ILE A 373 2241 2007 2662 231 -522 -209 O

ATOM 424 N LEU A 374 40.530 20.643 -14.656 1.00 18.68 N

ANISOU 424 N LEU A 374 2154 2125 2818 229 -542 -216 N

ATOM 425 CA LEU A 374 40.328 19.586 -15.652 1.00 16.99 C

ANISOU 425 CA LEU A 374 1981 1892 2582 281 -514 -144 C

ATOM 426 CB LEU A 374 40.251 20.197 -17.064 1.00 15.29 C

ANISOU 426 CB LEU A 374 1724 1644 2441 233 -453 -108 C

ATOM 427 CG LEU A 374 40.219 19.251 -18.265 1.00 15.44 C

ANISOU 427 CG LEU A 374 1766 1665 2434 277 -421 -57 C

ATOM 428 CD1 LEU A 374 38.992 18.305 -18.302 1.00 14.91 C

ANISOU 428 CD1 LEU A 374 1810 1543 2313 303 -413 -24 C

ATOM 429 CD2 LEU A 374 40.303 20.021 -19.573 1.00 16.74 C

ANISOU 429 CD2 LEU A 374 1884 1827 2651 222 -365 -20 C

ATOM 430 C LEU A 374 41.486 18.592 -15.607 1.00 17.53 C

ANISOU 430 C LEU A 374 2018 2033 2611 368 -562 -144 C

ATOM 431 O LEU A 374 42.663 19.008 -15.663 1.00 18.31 O

ANISOU 431 O LEU A 374 2004 2204 2748 365 -586 -185 O

ATOM 432 N ARG A 375 41.161 17.302 -15.495 1.00 16.74 N

ANISOU 432 N ARG A 375 2010 1906 2444 445 -575 -102 N

ATOM 433 CA ARG A 375 42.128 16.231 -15.749 1.00 17.32 C

ANISOU 433 CA ARG A 375 2066 2016 2497 550 -609 -93 C

ATOM 434 CB ARG A 375 42.224 15.233 -14.612 1.00 17.75 C

ANISOU 434 CB ARG A 375 2205 2070 2469 639 -680 -69 C

ATOM 435 CG ARG A 375 43.006 15.772 -13.443 1.00 18.20 C

ANISOU 435 CG ARG A 375 2196 2225 2493 651 -761 -113 C

ATOM 436 CD ARG A 375 42.926 14.833 -12.281 1.00 20.67 C

ANISOU 436 CD ARG A 375 2618 2538 2698 734 -831 -66 C

ATOM 437 NE ARG A 375 43.721 15.319 -11.164 1.00 22.34 N

ANISOU 437 NE ARG A 375 2762 2868 2856 753 -925 -115 N

ATOM 438 CZ ARG A 375 43.603 14.892 -9.911 1.00 24.36 C

ANISOU 438 CZ ARG A 375 3108 3157 2992 799 -993 -83 C

ATOM 439 NH1 ARG A 375 42.718 13.955 -9.595 1.00 26.04 N

ANISOU 439 NH1 ARG A 375 3486 3280 3130 822 -967 10 N

ATOM 440 NH2 ARG A 375 44.383 15.409 -8.971 1.00 27.64 N

ANISOU 440 NH2 ARG A 375 3448 3702 3353 812 -1089 -144 N

ATOM 441 C ARG A 375 41.742 15.522 -17.009 1.00 17.19 C

ANISOU 441 C ARG A 375 2092 1945 2495 569 -551 -62 C

ATOM 442 O ARG A 375 40.566 15.227 -17.252 1.00 16.68 O

ANISOU 442 O ARG A 375 2122 1802 2414 533 -514 -29 O

ATOM 443 N LYS A 376 42.743 15.264 -17.830 1.00 17.94 N

ANISOU 443 N LYS A 376 2106 2093 2619 621 -540 -83 N

ATOM 444 CA LYS A 376 42.484 14.748 -19.154 1.00 18.80 C

ANISOU 444 CA LYS A 376 2238 2172 2732 630 -477 -75 C

ATOM 445 CB LYS A 376 42.485 15.948 -20.089 1.00 19.04 C

ANISOU 445 CB LYS A 376 2186 2243 2804 530 -415 -73 C

ATOM 446 CG LYS A 376 42.472 15.657 -21.514 1.00 22.12 C

ANISOU 446 CG LYS A 376 2573 2649 3183 532 -351 -70 C

ATOM 447 CD LYS A 376 43.216 16.738 -22.249 1.00 25.06 C

ANISOU 447 CD LYS A 376 2826 3105 3592 464 -298 -68 C

ATOM 448 CE LYS A 376 43.015 16.490 -23.721 1.00 26.93 C

ANISOU 448 CE LYS A 376 3079 3367 3787 456 -227 -54 C

ATOM 449 NZ LYS A 376 43.691 15.264 -24.120 1.00 27.50 N

ANISOU 449 NZ LYS A 376 3143 3478 3828 566 -218 -111 N

ATOM 450 C LYS A 376 43.569 13.729 -19.486 1.00 19.24 C

ANISOU 450 C LYS A 376 2256 2266 2787 756 -493 -106 C

ATOM 451 O LYS A 376 44.650 13.770 -18.915 1.00 20.06 O

ANISOU 451 O LYS A 376 2269 2448 2907 818 -543 -135 O

ATOM 452 N ALA A 377 43.257 12.766 -20.348 1.00 19.46 N

ANISOU 452 N ALA A 377 2354 2239 2799 802 -456 -112 N

ATOM 453 CA ALA A 377 44.251 11.822 -20.856 1.00 20.59 C

ANISOU 453 CA ALA A 377 2459 2411 2953 930 -454 -160 C

ATOM 454 CB ALA A 377 44.120 10.473 -20.155 1.00 20.90 C

ANISOU 454 CB ALA A 377 2623 2340 2977 1047 -512 -144 C

ATOM 455 C ALA A 377 44.003 11.728 -22.371 1.00 20.76 C

ANISOU 455 C ALA A 377 2480 2447 2962 897 -367 -192 C

ATOM 456 O ALA A 377 43.249 12.533 -22.902 1.00 20.64 O

ANISOU 456 O ALA A 377 2473 2438 2933 780 -325 -163 O

ATOM 457 N THR A 378 44.622 10.780 -23.061 1.00 22.11 N

ANISOU 457 N THR A 378 2642 2627 3133 1005 -342 -253 N

ATOM 458 CA THR A 378 44.428 10.601 -24.505 1.00 22.78 C

ANISOU 458 CA THR A 378 2731 2741 3183 981 -260 -299 C

ATOM 459 CB THR A 378 45.231 9.415 -25.017 1.00 23.45 C

ANISOU 459 CB THR A 378 2808 2825 3277 1131 -241 -389 C

ATOM 460 OG1 THR A 378 46.575 9.539 -24.551 1.00 23.66 O

ANISOU 460 OG1 THR A 378 2689 2950 3349 1227 -263 -415 O

ATOM 461 CG2 THR A 378 45.203 9.355 -26.561 1.00 23.42 C

ANISOU 461 CG2 THR A 378 2787 2895 3216 1103 -145 -456 C

ATOM 462 C THR A 378 42.959 10.423 -24.902 1.00 22.92 C

ANISOU 462 C THR A 378 2886 2662 3160 891 -249 -274 C

ATOM 463 O THR A 378 42.361 9.373 -24.664 1.00 23.13 O

ANISOU 463 O THR A 378 3038 2563 3187 929 -277 -288 O

ATOM 464 N ARG A 379 42.395 11.464 -25.505 1.00 23.07 N

ANISOU 464 N ARG A 379 2878 2739 3150 770 -213 -235 N

ATOM 465 CA ARG A 379 41.001 11.461 -25.957 1.00 23.17 C

ANISOU 465 CA ARG A 379 2988 2693 3123 683 -211 -213 C

ATOM 466 CB ARG A 379 40.838 10.623 -27.240 1.00 23.76 C

ANISOU 466 CB ARG A 379 3108 2781 3137 707 -169 -291 C

ATOM 467 CG ARG A 379 41.771 11.029 -28.390 1.00 23.77 C

ANISOU 467 CG ARG A 379 3011 2933 3089 720 -95 -325 C

ATOM 468 CD ARG A 379 41.330 10.371 -29.694 1.00 25.40 C

ANISOU 468 CD ARG A 379 3277 3169 3207 718 -57 -401 C

ATOM 469 NE ARG A 379 40.022 10.902 -30.106 1.00 24.50 N

ANISOU 469 NE ARG A 379 3216 3051 3041 606 -80 -347 N

ATOM 470 CZ ARG A 379 39.252 10.392 -31.059 1.00 24.10 C

ANISOU 470 CZ ARG A 379 3232 3014 2911 577 -79 -404 C

ATOM 471 NH1 ARG A 379 39.641 9.323 -31.758 1.00 25.54 N

ANISOU 471 NH1 ARG A 379 3449 3204 3050 644 -47 -530 N

ATOM 472 NH2 ARG A 379 38.099 10.974 -31.317 1.00 22.39 N

ANISOU 472 NH2 ARG A 379 3041 2808 2658 485 -115 -345 N

ATOM 473 C ARG A 379 40.061 10.981 -24.854 1.00 23.18 C

ANISOU 473 C ARG A 379 3094 2563 3150 668 -268 -182 C

ATOM 474 O ARG A 379 39.189 10.137 -25.092 1.00 24.70 O

ANISOU 474 O ARG A 379 3388 2671 3327 652 -272 -208 O

ATOM 475 N ARG A 380 40.242 11.534 -23.654 1.00 22.60 N

ANISOU 475 N ARG A 380 2994 2481 3113 663 -306 -133 N

ATOM 476 CA ARG A 380 39.482 11.149 -22.465 1.00 22.87 C

ANISOU 476 CA ARG A 380 3120 2413 3156 648 -350 -96 C

ATOM 477 CB ARG A 380 40.063 9.888 -21.829 1.00 23.67 C

ANISOU 477 CB ARG A 380 3291 2436 3267 763 -386 -109

ATOM 478 CG ARG A 380 39.313 9.349 -20.612 1.00 25.57 C

ANISOU 478 CG ARG A 380 3648 2566 3499 747 -421 -54 C

ATOM 479 CD ARG A 380 40.092 8.171 -20.021 1.00 30.01 C

ANISOU 479 CD ARG A 380 4280 3051 4071 882 -464 -48 C

ATOM 480 NE ARG A 380 39.887 8.025 -18.572 1.00 39.22 N

ANISOU 480 NE ARG A 380 5520 4172 5211 888 -512 30 N

ATOM 481 CZ ARG A 380 40.796 7.522 -17.733 1.00 40.49 C

ANISOU 481 CZ ARG A 380 5699 4323 5363 1013 -577 62 C

ATOM 482 NH1 ARG A 380 41.968 7.110 -18.193 1.00 43.42 N

ANISOU 482 NH1 ARG A 380 6006 4723 5768 1149 -600 15 N

ATOM 483 NH2 ARG A 380 40.537 7.434 -16.435 1.00 42.81 N

ANISOU 483 NH2 ARG A 380 6069 4590 5607 1008 -619 141 N

ATOM 484 C ARG A 380 39.490 12.279 -21.455 1.00 21.00 C

ANISOU 484 C ARG A 380 2828 2214 2937 601 -375 -50 C

ATOM 485 O ARG A 380 40.551 12.775 -21.067 1.00 20.79 O

ANISOU 485 O ARG A 380 2713 2256 2929 638 -393 -57 O

ATOM 486 N LEU A 381 38.288 12.705 -21.066 1.00 19.70 N

ANISOU 486 N LEU A 381 2706 2009 2769 514 -373 -18 N

ATOM 487 CA LEU A 381 38.090 13.567 -19.904 1.00 18.41 C

ANISOU 487 CA LEU A 381 2522 1857 2616 475 -396 9 C

ATOM 488 CB LEU A 381 36.745 14.289 -19.985 1.00 16.88 C

ANISOU 488 CB LEU A 381 2337 1645 2433 380 -372 26 C

ATOM 489 CG LEU A 381 36.469 15.343 -18.928 1.00 17.01 C

ANISOU 489 CG LEU A 381 2323 1675 2467 338 -382 32 C

ATOM 490 CD1 LEU A 381 35.655 16.492 -19.499 1.00 12.78 C

ANISOU 490 CD1 LEU A 381 1738 1145 1973 273 -356 41 C

ATOM 491 CD2 LEU A 381 35.764 14.667 -17.749 1.00 15.08 C

ANISOU 491 CD2 LEU A 381 2164 1384 2181 330 -388 44 C

ATOM 492 C LEU A 381 38.123 12.638 -18.694 1.00 18.24 C

ANISOU 492 C LEU A 381 2589 1780 2564 525 -433 27 C

ATOM 493 O LEU A 381 37.296 11.748 -18.564 1.00 17.60 O

ANISOU 493 O LEU A 381 2610 1616 2464 509 -422 44 O

ATOM 494 N VAL A 382 39.085 12.854 -17.814 1.00 18.87 N

ANISOU 494 N VAL A 382 2628 1907 2635 580 -480 26 N

ATOM 495 CA VAL A 382 39.212 12.031 -16.604 1.00 19.46 C

ANISOU 495 CA VAL A 382 2791 1944 2660 640 -528 61 C

ATOM 496 CB VAL A 382 40.671 11.956 -16.074 1.00 19.74 C

ANISOU 496 CB VAL A 382 2760 2052 2688 749 -598 48 C

ATOM 497 CG1 VAL A 382 40.736 11.203 -14.743 1.00 20.37 C

ANISOU 497 CG1 VAL A 382 2942 2102 2697 814 -661 104 C

ATOM 498 CG2 VAL A 382 41.561 11.303 -17.093 1.00 19.70 C

ANISOU 498 CG2 VAL A 382 2711 2051 2723 843 -593 16 C

ATOM 499 C VAL A 382 38.274 12.584 -15.548 1.00 19.47 C

ANISOU 499 C VAL A 382 2832 1944 2622 558 -521 84 C

ATOM 500 O VAL A 382 37.472 11.840 -14.971 1.00 19.89 O

ANISOU 500 O VAL A 382 2999 1928 2631 538 -507 128 O

ATOM 501 N GLN A 383 38.362 13.885 -15.307 1.00 18.92 N

ANISOU 501 N GLN A 383 2671 1946 2571 507 -521 49 N

ATOM 502 CA GLN A 383 37.483 14.517 -14.335 1.00 20.00 C

ANISOU 502 CA GLN A 383 2833 2091 2675 436 -506 46 C

ATOM 503 CB GLN A 383 37.874 14.122 -12.908 1.00 21.18 C

ANISOU 503 CB GLN A 383 3042 2275 2732 481 -560 66 C

ATOM 504 CG GLN A 383 36.899 14.605 -11.894 1.00 28.38 C

ANISOU 504 CG GLN A 383 3993 3203 3587 409 -528 59 C

ATOM 505 CD GLN A 383 36.981 13.887 -10.544 1.00 37.43 C

ANISOU 505 CD GLN A 383 5244 4372 4605 445 -564 109 C

ATOM 506 OE1 GLN A 383 38.033 13.320 -10.146 1.00 36.64 O

ANISOU 506 OE1 GLN A 383 5163 4301 4457 540 -643 139 O

ATOM 507 NE2 GLN A 383 35.848 13.911 -9.823 1.00 39.52 N

ANISOU 507 NE2 GLN A 383 5575 4633 4808 372 -503 122 N

ATOM 508 C GLN A 383 37.476 16.041 -14.523 1.00 18.54 C

ANISOU 508 C GLN A 383 2542 1952 2551 374 -491 -8 C

ATOM 509 O GLN A 383 38.482 16.611 -14.934 1.00 18.67 O

ANISOU 509 O GLN A 383 2468 2013 2613 390 -513 -37 O

ATOM 510 N LEU A 384 36.330 16.663 -14.252 1.00 16.78 N

ANISOU 510 N LEU A 384 2330 1708 2337 305 -448 -21 N

ATOM 511 CA LEU A 384 36.156 18.111 -14.349 1.00 16.11 C

ANISOU 511 CA LEU A 384 2165 1634 2321 254 -431 -70 C

ATOM 512 CB LEU A 384 35.379 18.478 -15.633 1.00 14.20 C

ANISOU 512 CB LEU A 384 1897 1346 2153 221 -387 -47 C

ATOM 513 CG LEU A 384 35.100 19.947 -15.893 1.00 15.78 C

ANISOU 513 CG LEU A 384 2031 1526 2439 180 -369 -75 C

ATOM 514 CD1 LEU A 384 36.401 20.725 -16.207 1.00 10.81 C

ANISOU 514 CD1 LEU A 384 1330 915 1863 174 -391 -92 C

ATOM 515 CD2 LEU A 384 34.054 20.107 -16.999 1.00 14.91 C

ANISOU 515 CD2 LEU A 384 1914 1378 2373 164 -338 -36 C

ATOM 516 C LEU A 384 35.367 18.584 -13.150 1.00 16.11 C

ANISOU 516 C LEU A 384 2191 1646 2283 219 -413 -111 C

ATOM 517 O LEU A 384 34.264 18.059 -12.911 1.00 16.54 O

ANISOU 517 O LEU A 384 2303 1680 2301 197 -371 -89 O

ATOM 518 N ILE A 385 35.903 19.575 -12.422 1.00 16.23 N

ANISOU 518 N ILE A 385 2159 1700 2309 206 -439 -182 N

ATOM 519 CA ILE A 385 35.136 20.337 -11.409 1.00 17.22 C

ANISOU 519 CA ILE A 385 2291 1838 2415 170 -411 -252 C

ATOM 520 CB ILE A 385 35.776 20.285 -9.974 1.00 19.18 C

ANISOU 520 CB ILE A 385 2565 2173 2549 183 -460 -306 C

ATOM 521 CG1 ILE A 385 36.149 18.859 -9.636 1.00 21.06 C

ANISOU 521 CG1 ILE A 385 2884 2446 2673 236 -496 -222 C

ATOM 522 CD1 ILE A 385 37.060 18.725 -8.443 1.00 25.03 C

ANISOU 522 CD1 ILE A 385 3405 3048 3060 273 -575 -251 C

ATOM 523 CG2 ILE A 385 34.780 20.792 -8.871 1.00 18.63 C

ANISOU 523 CG2 ILE A 385 2525 2131 2421 148 -410 -379 C

ATOM 524 C ILE A 385 35.022 21.812 -11.817 1.00 17.38 C

ANISOU 524 C ILE A 385 2235 1809 2560 134 -392 -315 C

ATOM 525 O ILE A 385 36.038 22.477 -12.052 1.00 16.35 O

ANISOU 525 O ILE A 385 2047 1678 2489 122 -428 -346 O

ATOM 526 N VAL A 386 33.788 22.308 -11.888 1.00 17.59 N

ANISOU 526 N VAL A 386 2260 1791 2632 116 -336 -334 N

ATOM 527 CA VAL A 386 33.497 23.673 -12.328 1.00 17.46 C

ANISOU 527 CA VAL A 386 2187 1700 274.

99. 317 -379 C

ATOM 528 CB VAL A 386 32.501 23.721 -13.521 1.00 17.32 C

ANISOU 528 CB VAL A 386 2153 1623 2805 111 -285 -308 C

ATOM 529 CG1 VAL A 386 32.435 25.126 -14.121 1.00 14.48 C

ANISOU 529 CG1 VAL A 386 1746 1168 2586 108 -281 -322 C

ATOM 530 CG2 VAL A 386 32.875 22.722 -14.622 1.00 14.00 C

ANISOU 530 CG2 VAL A 386 1747 1216 2356 121 -303 -206 C

ATOM 531 C VAL A 386 32.924 24.512 -11.181 1.00 19.48 C

ANISOU 531 C VAL A 386 2439 1958 300.

89. 289 -498 C

ATOM 532 O VAL A 386 32.052 24.065 -10.400 1.00 19.17 O

ANISOU 532 O VAL A 386 2432 1971 288.

93. 248 -524 O

ATOM 533 N SER A 387 33.434 25.741 -11.087 1.00 20.06 N

ANISOU 533 N SER A 387 2475 1975 317.

69. 304 -576 N

ATOM 534 CA SER A 387 32.894 26.762 -10.198 1.00 20.65 C

ANISOU 534 CA SER A 387 2541 2021 328.

64. 273 -709 C

ATOM 535 CB SER A 387 34.004 27.197 -9.236 1.00 21.25 C

ANISOU 535 CB SER A 387 2612 2141 332.

26. 322 -822 C

ATOM 536 OG SER A 387 33.536 28.081 -8.225 1.00 25.92 O

ANISOU 536 OG SER A 387 3205 2723 392.

20. 293 -979 O

ATOM 537 C SER A 387 32.403 27.938 -11.076 1.00 20.74 C

ANISOU 537 C SER A 387 2515 1887 347.

75. 250 -705 C

ATOM 538 O SER A 387 33.153 28.448 -11.920 1.00 20.93 O

ANISOU 538 O SER A 387 2521 1834 359.

50. 277 -654 O

ATOM 539 N GLY A 388 31.171 28.394 -10.876 1.00 20.37 N

ANISOU 539 N GLY A 388 2457 1802 3480 115 -199 -755 N

ATOM 540 CA GLY A 388 30.607 29.375 -11.771 1.00 20.03 C

ANISOU 540 CA GLY A 388 2385 1621 3603 151 -188 -725 C

ATOM 541 C GLY A 388 29.641 30.315 -11.094 1.00 21.29 C

ANISOU 541 C GLY A 388 2524 1722 3843 198 -142 -856 C

ATOM 542 O GLY A 388 29.139 30.030 -10.008 1.00 20.82 O

ANISOU 542 O GLY A 388 2464 1757 3689 204 -100 -961 O

ATOM 543 N LYS A 389 29.391 31.447 -11.743 1.00 22.34 N

ANISOU 543 N LYS A 389 2643 1697 4149 235 -144 -847 N

ATOM 544 CA LYS A 389 28.404 32.440 -11.252 1.00 23.74 C

ANISOU 544 CA LYS A 389 2793 1788 4438 308 -101 -972 C

ATOM 545 CB LYS A 389 28.635 33.761 -11.940 1.00 24.80 C

ANISOU 545 CB LYS A 389 2942 1708 4771 330 -123 -951 C

ATOM 546 CG LYS A 389 29.884 34.437 -11.447 1.00 28.40 C

ANISOU 546 CG LYS A 389 3437 2087 5267 239 -141 -1042 C

ATOM 547 CD LYS A 389 30.035 35.791 -12.096 1.00 35.05 C

ANISOU 547 CD LYS A 389 4306 2688 6324 250 -150 -1019 C

ATOM 548 CE LYS A 389 31.177 36.562 -11.441 1.00 41.60 C

ANISOU 548 CE LYS A 389 5164 3432 7212 145 -160 -1153 C

ATOM 549 NZ LYS A 389 31.822 37.562 -12.391 1.00 47.46 N

ANISOU 549 NZ LYS A 389 5944 3955 8136 93 -174 -1054 N

ATOM 550 C LYS A 389 26.964 32.018 -11.437 1.00 23.29 C

ANISOU 550 C LYS A 389 2680 1796 4372 389 -64 -947 C

ATOM 551 O LYS A 389 26.103 32.459 -10.703 1.00 24.56 O

ANISOU 551 O LYS A 389 2804 1962 4567 446 -11 -1079 O

ATOM 552 N ASP A 390 26.725 31.102 -12.371 1.00 22.47 N

ANISOU 552 N ASP A 390 2563 1759 4214 388 -89 -794 N

ATOM 553 CA ASP A 390 25.370 30.703 -12.704 1.00 23.07 C

ANISOU 553 CA ASP A 390 2569 1900 4296 454 -66 -765 C

ATOM 554 CB ASP A 390 24.663 31.853 -13.445 1.00 24.00 C

ANISOU 554 CB ASP A 390 2644 1876 4601 562 -88 -743 C

ATOM 555 CG ASP A 390 25.432 32.299 -14.704 1.00 24.13 C

ANISOU 555 CG ASP A 390 2712 1766 4691 555 -157 -587 C

ATOM 556 OD1 ASP A 390 25.404 31.534 -15.677 1.00 25.37 O

ANISOU 556 OD1 ASP A 390 2865 1991 4783 541 -195 -449 O

ATOM 557 OD2 ASP A 390 26.078 33.378 -14.716 1.00 18.12 O

ANISOU 557 OD2 ASP A 390 1997 842 4045 553 -168 -605 O

ATOM 558 C ASP A 390 25.431 29.453 -13.563 1.00 21.82 C

ANISOU 558 C ASP A 390 2416 1838 4036 412 -98 -618 C

ATOM 559 O ASP A 390 26.473 29.107 -14.095 1.00 21.61 O

ANISOU 559 O ASP A 390 2445 1800 3967 359 -140 -529 O

ATOM 560 N GLU A 391 24.289 28.816 -13.752 1.00 22.29 N

ANISOU 560 N GLU A 391 2410 1991 4069 437 -77 -602 N

ATOM 561 CA GLU A 391 24.220 27.543 -14.442 1.00 21.52 C

ANISOU 561 CA GLU A 391 2317 1987 3871 387 -99 -494 C

ATOM 562 CB GLU A 391 22.839 26.928 -14.190 1.00 22.15 C

ANISOU 562 CB GLU A 391 2309 2181 3927 393 -50 -536 C

ATOM 563 CG GLU A 391 22.286 26.000 -15.243 1.00 24.99 C

ANISOU 563 CG GLU A 391 2632 2607 4255 372 -88 -439 C

ATOM 564 CD GLU A 391 20.751 25.986 -15.206 1.00 33.67 C

ANISOU 564 CD GLU A 391 3596 3789 5407 410 -56 -495 C

ATOM 565 OE1 GLU A 391 20.154 25.746 -14.111 1.00 34.20 O

ANISOU 565 OE1 GLU A 391 3622 3935 5438 379 35 -596 O

ATOM 566 OE2 GLU A 391 20.138 26.247 -16.270 1.00 38.52 O

ANISOU 566 OE2 GLU A 391 4139 4401 6095 472 -121 -439 O

ATOM 567 C GLU A 391 24.611 27.602 -15.922 1.00 20.48 C

ANISOU 567 C GLU A 391 2204 1800 3778 403 -176 -352 C

ATOM 568 O GLU A 391 25.229 26.686 -16.401 1.00 19.95 O

ANISOU 568 O GLU A 391 2183 1778 3619 346 -199 -277 O

ATOM 569 N GLN A 392 24.288 28.689 -16.609 1.00 21.46 N

ANISOU 569 N GLN A 392 2299 1824 4031 484 -212 -317 N

ATOM 570 CA GLN A 392 24.666 28.910 -18.002 1.00 23.52 C

ANISOU 570 CA GLN A 392 2587 2032 4318 502 -281 -172 C

ATOM 571 CB GLN A 392 23.926 30.147 -18.557 1.00 24.65 C

ANISOU 571 CB GLN A 392 2688 2067 4610 617 -317 -138 C

ATOM 572 CG GLN A 392 24.537 30.860 -19.769 1.00 28.63 C

ANISOU 572 CG GLN A 392 3252 2461 5164 639 -376 13 C

ATOM 573 CD GLN A 392 24.305 32.416 -19.753 1.00 30.83 C

ANISOU 573 CD GLN A 392 3540 2551 5624 735 -387 15 C

ATOM 574 OE1 GLN A 392 25.010 33.190 -19.035 1.00 34.80 O

ANISOU 574 OE1 GLN A 392 4092 2924 6205 705 -349 -58 O

ATOM 575 NE2 GLN A 392 23.321 32.867 -20.548 1.00 33.14 N

ANISOU 575 NE2 GLN A 392 3784 2821 5985 853 -447 94 N

ATOM 576 C GLN A 392 26.188 29.017 -18.189 1.00 22.62 C

ANISOU 576 C GLN A 392 2561 1858 4175 433 -289 -120 C

ATOM 577 O GLN A 392 26.726 28.443 -19.125 1.00 21.91 O

ANISOU 577 O GLN A 392 2503 1807 4016 398 -319 -17 O

ATOM 578 N SER A 393 26.877 29.730 -17.295 1.00 22.81 N

ANISOU 578 N SER A 393 2615 1801 4249 409 -260 -206 N

ATOM 579 CA SER A 393 28.347 29.794 -17.315 1.00 21.99 C

ANISOU 579 CA SER A 393 2570 1664 4121 331 -264 -183 C

ATOM 580 CB SER A 393 28.857 30.874 -16.346 1.00 23.44 C

ANISOU 580 CB SER A 393 2770 1738 4397 313 -242 -300 C

ATOM 581 OG SER A 393 28.140 32.078 -16.569 1.00 25.29 O

ANISOU 581 OG SER A 393 2992 1830 4786 390 -243 -305 O

ATOM 582 C SER A 393 29.011 28.464 -16.993 1.00 20.66 C

ANISOU 582 C SER A 393 2422 1626 3801 265 -259 -189 C

ATOM 583 O SER A 393 30.049 28.132 -17.552 1.00 19.87 O

ANISOU 583 O SER A 393 2350 1542 3659 219 -276 -122 O

ATOM 584 N ILE A 394 28.422 27.713 -16.073 1.00 20.77 N

ANISOU 584 N ILE A 394 2422 1732 3737 263 -230 -268 N

ATOM 585 CA ILE A 394 28.889 26.369 -15.747 1.00 19.11 C

ANISOU 585 CA ILE A 394 2244 1630 3386 214 -227 -260 C

ATOM 586 CB ILE A 394 28.139 25.782 -14.497 1.00 19.85 C

ANISOU 586 CB ILE A 394 2333 1806 3402 206 -179 -352 C

ATOM 587 CG1 ILE A 394 28.509 26.606 -13.259 1.00 20.43 C

ANISOU 587 CG1 ILE A 394 2415 1856 3490 201 -158 -477 C

ATOM 588 CD1 ILE A 394 27.499 26.518 -12.109 1.00 22.75 C

ANISOU 588 CD1 ILE A 394 2688 2218 3738 210 -93 -583 C

ATOM 589 CG2 ILE A 394 28.435 24.278 -14.274 1.00 15.59 C

ANISOU 589 CG2 ILE A 394 1843 1358 2723 163 -177 -313 C

ATOM 590 C ILE A 394 28.784 25.474 -16.977 1.00 18.68 C

ANISOU 590 C ILE A 394 2195 1619 3284 212 -254 -148 C

ATOM 591 O ILE A 394 29.760 24.825 -17.311 1.00 17.57 O

ANISOU 591 O ILE A 394 2090 1507 3080 182 -270 -104 O

ATOM 592 N ALA A 395 27.630 25.500 -17.663 1.00 19.22 N

ANISOU 592 N ALA A 395 2220 1695 3386 250 -262 -113 N

ATOM 593 CA ALA A 395 27.401 24.738 -18.901 1.00 19.01 C

ANISOU 593 CA ALA A 395 2194 1718 3313 248 -295 -23 C

ATOM 594 CB ALA A 395 25.980 24.956 -19.419 1.00 18.56 C

ANISOU 594 CB ALA A 395 2065 1683 3305 297 -314 -13 C

ATOM 595 C ALA A 395 28.416 25.074 -19.990 1.00 19.20 C

ANISOU 595 C ALA A 395 2250 1706 3340 245 -327 70 C

ATOM 596 O ALA A 395 28.898 24.171 -20.671 1.00 18.93 O

ANISOU 596 O ALA A 395 2244 1727 3223 220 -339 115 O

ATOM 597 N GLU A 396 28.719 26.364 -20.157 1.00 20.22 N

ANISOU 597 N GLU A 396 2377 1739 3567 267 -332 96 N

ATOM 598 CA GLU A 396 29.710 26.818 -21.142 1.00 21.09 C

ANISOU 598 CA GLU A 396 2517 1810 3684 247 -345 193 C

ATOM 599 CB GLU A 396 29.807 28.341 -21.147 1.00 22.89 C

ANISOU 599 CB GLU A 396 2749 1899 4047 266 -343 216 C

ATOM 600 CG GLU A 396 28.607 29.009 -21.787 1.00 27.44 C

ANISOU 600 CG GLU A 396 3306 2429 4693 349 -378 278 C

ATOM 601 CD GLU A 396 28.571 30.513 -21.606 1.00 31.59 C

ANISOU 601 CD GLU A 396 3844 2785 5373 385 -375 287 C

ATOM 602 OE1 GLU A 396 29.466 31.075 -20.945 1.00 37.15 O

ANISOU 602 OE1 GLU A 396 4573 3406 6136 328 -342 230 O

ATOM 603 OE2 GLU A 396 27.632 31.141 -22.145 1.00 34.90 O

ANISOU 603 OE2 GLU A 396 4250 3151 5862 473 -412 349 O

ATOM 604 C GLU A 396 31.090 26.181 -20.894 1.00 19.62 C

ANISOU 604 C GLU A 396 2357 1667 3430 186 -325 174 C

ATOM 605 O GLU A 396 31.755 25.774 -21.820 1.00 19.19 O

ANISOU 605 O GLU A 396 2317 1657 3319 166 -327 242 O

ATOM 606 N ALA A 397 31.480 26.093 -19.631 1.00 18.63 N

ANISOU 606 N ALA A 397 2231 1543 3306 164 -309 75 N

ATOM 607 CA ALA A 397 32.722 25.456 -19.210 1.00 18.01 C

ANISOU 607 CA ALA A 397 2163 1517 3164 125 -305 44 C

ATOM 608 CB ALA A 397 32.994 25.795 -17.741 1.00 17.36 C

ANISOU 608 CB ALA A 397 2076 1422 3099 108 -300 -69 C

ATOM 609 C ALA A 397 32.768 23.936 -19.457 1.00 16.96 C

ANISOU 609 C ALA A 397 2052 1477 2914 133 -311 60 C

ATOM 610 O ALA A 397 33.775 23.398 -19.924 1.00 17.05 O

ANISOU 610 O ALA A 397 2067 1532 2880 123 -313 85 O

ATOM 611 N ILE A 398 31.668 23.250 -19.152 1.00 17.13 N

ANISOU 611 N ILE A 398 2086 1526 2898 151 -309 38 N

ATOM 612 CA ILE A 398 31.536 21.827 -19.422 1.00 15.91 C

ANISOU 612 CA ILE A 398 1963 1430 2651 150 -312 51 C

ATOM 613 CB ILE A 398 30.199 21.264 -18.834 1.00 17.18 C

ANISOU 613 CB ILE A 398 2128 1608 2792 144 -297 15 C

ATOM 614 CG1 ILE A 398 30.119 21.527 -17.326 1.00 16.13 C

ANISOU 614 CG1 ILE A 398 2000 1471 2657 136 -271 -57 C

ATOM 615 CD1 ILE A 398 28.779 21.236 -16.716 1.00 16.58 C

ANISOU 615 CD1 ILE A 398 2043 1553 2705 121 -235 -95 C

ATOM 616 CG2 ILE A 398 30.022 19.747 -19.155 1.00 13.67 C

ANISOU 616 CG2 ILE A 398 1729 1199 2267 127 -297 27 C

ATOM 617 C ILE A 398 31.671 21.562 -20.922 1.00 16.07 C

ANISOU 617 C ILE A 398 1985 1475 2647 156 -326 121 C

ATOM 618 O ILE A 398 32.434 20.686 -21.326 1.00 16.26 O

ANISOU 618 O ILE A 398 2034 1535 2609 157 -326 128 O

ATOM 619 N ILE A 399 30.963 22.335 -21.741 1.00 16.42 N

ANISOU 619 N ILE A 399 2003 1502 2734 169 -339 169 N

ATOM 620 CA ILE A 399 31.042 22.212 -23.210 1.00 16.68 C

ANISOU 620 CA ILE A 399 2040 1574 2722 175 -356 243 C

ATOM 621 CB ILE A 399 30.128 23.237 -23.951 1.00 17.23 C

ANISOU 621 CB ILE A 399 2083 1621 2843 205 -385 310 C

ATOM 622 CG1 ILE A 399 28.652 22.926 -23.683 1.00 16.60 C

ANISOU 622 CG1 ILE A 399 1968 1565 2776 225 -410 268 C

ATOM 623 CD1 ILE A 399 27.669 24.079 -24.032 1.00 17.54 C

ANISOU 623 CD1 ILE A 399 2040 1648 2976 281 -446 315 C

ATOM 624 CG2 ILE A 399 30.379 23.228 -25.492 1.00 18.27 C

ANISOU 624 CG2 ILE A 399 2231 1807 2903 209 -404 401 C

ATOM 625 C ILE A 399 32.467 22.321 -23.722 1.00 17.17 C

ANISOU 625 C ILE A 399 2111 1650 2761 159 -335 277 C

ATOM 626 O ILE A 399 32.926 21.437 -24.454 1.00 17.83 O

ANISOU 626 O ILE A 399 2214 1798 2764 160 -329 282 O

ATOM 627 N VAL A 400 33.152 23.398 -23.336 1.00 16.69 N

ANISOU 627 N VAL A 400 2033 1534 2776 141 -318 289 N

ATOM 628 CA VAL A 400 34.542 23.641 -23.732 1.00 16.70 C

ANISOU 628 CA VAL A 400 2020 1553 2773 109 -288 316 C

ATOM 629 CB VAL A 400 35.026 25.034 -23.221 1.00 16.70 C

ANISOU 629 CB VAL A 400 1997 1463 288.

69. 273 321 C

ATOM 630 CG1 VAL A 400 36.523 25.234 -23.427 1.00 15.47 C

ANISOU 630 CG1 VAL A 400 1803 1337 273.

16. 236 327 C

ATOM 631 CG2 VAL A 400 34.216 26.116 -23.893 1.00 16.90 C

ANISOU 631 CG2 VAL A 400 2039 1410 297.

79. 281 410 C

ATOM 632 C VAL A 400 35.510 22.529 -23.314 1.00 15.98 C

ANISOU 632 C VAL A 400 1922 1527 2623 114 -279 252 C

ATOM 633 O VAL A 400 36.327 22.104 -24.112 1.00 17.42 O

ANISOU 633 O VAL A 400 2094 1773 2753 112 -256 272 O

ATOM 634 N ALA A 401 35.406 22.061 -22.079 1.00 16.30 N

ANISOU 634 N ALA A 401 1971 1556 2666 128 -297 178 N

ATOM 635 CA ALA A 401 36.199 20.909 -21.593 1.00 16.28 C

ANISOU 635 CA ALA A 401 1976 1604 2606 155 -305 128 C

ATOM 636 CB ALA A 401 35.953 20.689 -20.091 1.00 14.87 C

ANISOU 636 CB ALA A 401 1817 1404 2428 165 -328 68 C

ATOM 637 C ALA A 401 35.896 19.628 -22.378 1.00 16.82 C

ANISOU 637 C ALA A 401 2088 1709 2596 188 -304 136 C

ATOM 638 O ALA A 401 36.802 18.869 -22.684 1.00 18.03 O

ANISOU 638 O ALA A 401 2236 1907 2709 218 -296 118 O

ATOM 639 N MSE A 402 34.624 19.373 -22.681 1.00 17.03 N

ANISOU 639 N MSE A 402 2147 1717 2604 183 -313 147 N

ATOM 640 CA MSE A 402 34.253 18.142 -23.412 1.00 17.44 C

ANISOU 640 CA MSE A 402 2244 1796 2588 199 -316 135 C

ATOM 641 CB MSE A 402 32.737 17.935 -23.431 1.00 16.42 C

ANISOU 641 CB MSE A 402 2133 1649 2458 176 -333 130 C

ATOM 642 CG MSE A 402 32.140 17.462 -22.125 1.00 16.29 C

ANISOU 642 CG MSE A 402 2144 1590 2456 163 -332 92 C

ATOM 643 SE MSE A 402 30.183 17.395 -22.251 0.90 20.12 SE

ANISOU 643 SE MSE A 402 2609 2079 2958 119 -340 80 SE

ATOM 644 CE MSE A 402 29.774 16.578 -20.532 1.00 14.21 C

ANISOU 644 CE MSE A 402 1909 1287 2202 87 -307 39 C

ATOM 645 C MSE A 402 34.797 18.137 -24.843 1.00 17.04 C

ANISOU 645 C MSE A 402 2179 1807 2487 205 -298 163 C

ATOM 646 O MSE A 402 35.297 17.114 -25.295 1.00 17.79 O

ANISOU 646 O MSE A 402 2299 1933 2528 233 -288 126 O

ATOM 647 N VAL A 403 34.697 19.277 -25.541 1.00 17.61 N

ANISOU 647 N VAL A 403 2220 1894 2576 182 -292 230 N

ATOM 648 CA VAL A 403 35.335 19.465 -26.866 1.00 17.49 C

ANISOU 648 CA VAL A 403 2194 1951 2500 177 -261 275 C

ATOM 649 CB VAL A 403 34.977 20.843 -27.538 1.00 18.05 C

ANISOU 649 CB VAL A 403 2252 2014 2593 149 -261 380 C

ATOM 650 CG1 VAL A 403 35.759 21.042 -28.835 1.00 15.38 C

ANISOU 650 CG1 VAL A 403 1909 1761 2174 132 -215 441 C

ATOM 651 CG2 VAL A 403 33.475 20.963 -27.819 1.00 18.29 C

ANISOU 651 CG2 VAL A 403 2302 2033 2616 162 -316 405 C

ATOM 652 C VAL A 403 36.880 19.322 -26.774 1.00 18.33 C

ANISOU 652 C VAL A 403 2259 2096 2607 184 -216 250 C

ATOM 653 O VAL A 403 37.496 18.607 -27.563 1.00 18.16 O

ANISOU 653 O VAL A 403 2238 2149 2515 207 -185 224 O

ATOM 654 N PHE A 404 37.482 20.014 -25.804 1.00 18.22 N

ANISOU 654 N PHE A 404 2203 2042 2676 166 -213 246 N

ATOM 655 CA PHE A 404 38.935 20.002 -25.606 1.00 18.45 C

ANISOU 655 CA PHE A 404 2167 2120 2724 167 -180 215 C

ATOM 656 CB PHE A 404 39.279 20.946 -24.451 1.00 18.40 C

ANISOU 656 CB PHE A 404 2118 2060 2815 130 -197 203 C

ATOM 657 CG PHE A 404 40.743 21.047 -24.167 1.00 16.27 C

ANISOU 657 CG PHE A 404 1758 1850 2576 119 -176 163 C

ATOM 658 CD1 PHE A 404 41.538 21.926 -24.884 1.00 17.08 C

ANISOU 658 CD1 PHE A 404 1794 1990 2708 49 -116 207 C

ATOM 659 CE1 PHE A 404 42.921 22.016 -24.616 1.00 21.24 C

ANISOU 659 CE1 PHE A 404 2210 2589 3271 29 -94 157 C

ATOM 660 CZ PHE A 404 43.501 21.222 -23.619 1.00 19.15 C

ANISOU 660 CZ PHE A 404 1905 2364 3009 98 -148 68 C

ATOM 661 CE2 PHE A 404 42.718 20.351 -22.893 1.00 18.17 C

ANISOU 661 CE2 PHE A 404 1866 2192 2846 176 -211 40 C

ATOM 662 CD2 PHE A 404 41.325 20.260 -23.180 1.00 17.63 C

ANISOU 662 CD2 PHE A 404 1906 2047 2745 177 -217 86 C

ATOM 663 C PHE A 404 39.518 18.593 -25.332 1.00 18.68 C

ANISOU 663 C PHE A 404 2200 2187 2710 241 -190 135 C

ATOM 664 O PHE A 404 40.673 18.296 -25.683 1.00 18.92 O

ANISOU 664 O PHE A 404 2170 2292 2727 266 -154 105 O

ATOM 665 N SER A 405 38.712 17.745 -24.692 1.00 18.21 N

ANISOU 665 N SER A 405 2210 2070 2638 277 -233 102 N

ATOM 666 CA SER A 405 39.091 16.363 -24.380 1.00 18.68 C

ANISOU 666 CA SER A 405 2304 2127 2668 352 -249 41 C

ATOM 667 CB SER A 405 38.012 15.723 -23.496 1.00 18.57 C

ANISOU 667 CB SER A 405 2375 2027 2653 356 -290 32 C

ATOM 668 OG SER A 405 36.849 15.381 -24.246 1.00 16.66 O

ANISOU 668 OG SER A 405 2188 1765 2376 326 -287 37 O

ATOM 669 C SER A 405 39.340 15.491 -25.619 1.00 20.09 C

ANISOU 669 C SER A 405 2498 2356 2779 391 -214 8 C

ATOM 670 O SER A 405 40.066 14.496 -25.533 1.00 21.25 O

ANISOU 670 O SER A 405 2648 2509 2916 468 -213 -50 O

ATOM 671 N GLN A 406 38.723 15.866 -26.758 1.00 20.26 N

ANISOU 671 N GLN A 406 2533 2414 2751 345 -190 41 N

ATOM 672 CA GLN A 406 38.832 15.162 -28.048 1.00 20.05 C

ANISOU 672 CA GLN A 406 2527 2454 2636 368 -155 2 C

ATOM 673 CB GLN A 406 40.290 15.095 -28.531 1.00 19.99 C

ANISOU 673 CB GLN A 406 2441 2542 2612 409 -93 -31 C

ATOM 674 CG GLN A 406 40.906 16.472 -28.726 1.00 20.76 C

ANISOU 674 CG GLN A 406 2452 2702 2734 342 -49 46 C

ATOM 675 CD GLN A 406 42.332 16.414 -29.196 1.00 20.39 C

ANISOU 675 CD GLN A 406 2306 2766 2674 366 24 9 C

ATOM 676 OE1 GLN A 406 43.147 15.693 -28.645 1.00 19.25 O

ANISOU 676 OE1 GLN A 406 2117 2630 2566 44.

17. 66 O

ATOM 677 NE2 GLN A 406 42.640 17.179 -30.233 1.00 22.01 N

ANISOU 677 NE2 GLN A 406 2474 3065 2824 301 97 68 N

ATOM 678 C GLN A 406 38.164 13.777 -28.045 1.00 20.64 C

ANISOU 678 C GLN A 406 2691 2466 2684 406 -184 -74 C

ATOM 679 O GLN A 406 38.465 12.937 -28.887 1.00 22.16 O

ANISOU 679 O GLN A 406 2906 2696 2817 445 -157 -144 O

ATOM 680 N GLU A 407 37.248 13.554 -27.111 1.00 20.37 N

ANISOU 680 N GLU A 407 2710 2337 2695 385 -231 -65 N

ATOM 681 CA GLU A 407 36.556 12.268 -26.951 1.00 21.29 C

ANISOU 681 CA GLU A 407 2916 2369 2805 396 -254 -125 C

ATOM 682 CB GLU A 407 35.638 12.293 -25.718 1.00 19.97 C

ANISOU 682 CB GLU A 407 2786 2110 2691 355 -289 -92 C

ATOM 683 CG GLU A 407 36.371 12.188 -24.373 1.00 21.49 C

ANISOU 683 CG GLU A 407 2982 2253 2931 404 -301 -73 C

ATOM 684 CD GLU A 407 35.649 11.292 -23.352 1.00 21.16 C

ANISOU 684 CD GLU A 407 3033 2101 2906 391 -321 -72 C

ATOM 685 OE1 GLU A 407 34.688 10.585 -23.711 1.00 21.26 O

ANISOU 685 OE1 GLU A 407 3107 2062 2909 342 -319 -101 O

ATOM 686 OE2 GLU A 407 36.071 11.267 -22.189 1.00 20.34 O

ANISOU 686 OE2 GLU A 407 2943 1965 2820 424 -339 -43 O

ATOM 687 C GLU A 407 35.725 11.866 -28.158 1.00 22.08 C

ANISOU 687 C GLU A 407 3052 2504 2835 357 -256 -169 C

ATOM 688 O GLU A 407 35.066 12.694 -28.765 1.00 20.70 O

ANISOU 688 O GLU A 407 2846 2394 2624 304 -267 -123 O

ATOM 689 N ASP A 408 35.720 10.573 -28.461 1.00 23.34 N

ANISOU 689 N ASP A 408 3280 2611 2976 386 -253 -261 N

ATOM 690 CA ASP A 408 34.928 10.035 -29.544 1.00 24.61 C

ANISOU 690 CA ASP A 408 3481 2801 3068 344 -263 -332 C

ATOM 691 CB ASP A 408 35.160 8.530 -29.658 1.00 25.59 C

ANISOU 691 CB ASP A 408 3692 2830 3202 388 -253 -449 C

ATOM 692 CG ASP A 408 34.396 7.913 -30.801 1.00 27.72 C

ANISOU 692 CG ASP A 408 4003 3131 3397 336 -265 -551 C

ATOM 693 OD1 ASP A 408 34.710 8.279 -31.958 1.00 31.59 O

ANISOU 693 OD1 ASP A 408 4457 3762 3786 347 -246 -579 O

ATOM 694 OD2 ASP A 408 33.492 7.066 -30.549 1.00 28.73 O

ANISOU 694 OD2 ASP A 408 4201 3151 3564 276 -293 -607 O

ATOM 695 C ASP A 408 33.427 10.347 -29.389 1.00 24.65 C

ANISOU 695 C ASP A 408 3488 2793 3084 249 -310 -301 C

ATOM 696 O ASP A 408 32.784 10.796 -30.342 1.00 24.93 O

ANISOU 696 O ASP A 408 3495 2927 3051 207 -333 -299 O

ATOM 697 N ACYS A 409 32.869 10.126 -28.205 0.70 24.72 N

ANISOU 697 N ACYS A 409 3524 2697 3172 218 -325 -276 N

ATOM 698 N BCYS A 409 32.906 10.105 -28.182 0.30 24.11 N

ANISOU 698 N BCYS A 409 3448 2617 3096 220 -324 -276 N

ATOM 699 CA ACYS A 409 31.430 10.317 -28.021 0.70 25.22 C

ANISOU 699 CA ACYS A 409 3572 2756 3254 128 -359 -264 C

ATOM 700 CA BCYS A 409 31.506 10.359 -27.816 0.30 23.92 C

ANISOU 700 CA BCYS A 409 3408 2580 3101 132 -355 -254 C

ATOM 701 CB ACYS A 409 30.961 9.730 -26.681 0.70 25.40 C

ANISOU 701 CB ACYS A 409 3644 2652 335.

91. 351 -253 C ATOM 702 CB BCYS A 409 31.313 10.176 -26.307 0.30 23.45 C ANISOU 702 CB BCYS A 409 3378 2413 3118 117 -345 -213 C ATOM 703 SG ACYS A 409 31.124 10.858 -25.325 0.70 28.09 S ANISOU 703 SG ACYS A 409 3936 2990 3746 108 -341 -150 S ATOM 704 SG BCYS A 409 31.533 8.502 -25.712 0.30 24.62 S ANISOU 704 SG BCYS A 409 3655 2400 3300 125 -326 -269 S ATOM 705 C ACYS A 409 31.016 11.792 -28.173 0.70 23.86 C ANISOU 705 C ACYS A 409 3310 2680 3076 114 -379 -177 C ATOM 706 C BCYS A 409 31.060 11.762 -28.191 0.30 23.24 C ANISOU 706 C BCYS A 409 3233 2600 2995 116 -378 -179 C ATOM 707 O ACYS A 409 29.841 12.089 -28.420 0.70 23.73 O ANISOU 707 O ACYS A 409 3255 2703 305.

58. 417 -174 O ATOM 708 O BCYS A 409 29.914 11.985 -28.591 0.30 23.42 O ANISOU 708 O BCYS A 409 3222 2670 300.

61. 417 -184 O ATOM 709 N MSE A 410 31.991 12.696 -28.033 1.00 22.71 N ANISOU 709 N MSE A 410 3128 2566 2936 166 -357 -110 N ATOM 710 CA MSE A 410 31.811 14.092 -28.382 1.00 21.64 C ANISOU 710 CA MSE A 410 2925 2503 2796 162 -370 -25 C ATOM 711 CB MSE A 410 32.941 14.929 -27.770 1.00 21.38 C ANISOU 711 CB MSE A 410 2860 2456 2807 198 -336 34 C ATOM 712 CG MSE A 410 32.895 16.431 -28.071 1.00 19.41 C ANISOU 712 CG MSE A 410 2554 2246 2573 190 -339 129 C ATOM 713 SE MSE A 410 33.826 17.055 -29.687 0.90 23.28 SE ANISOU 713 SE MSE A 410 3027 2856 2961 199 -303 190 SE ATOM 714 CE MSE A 410 35.627 16.334 -29.341 1.00 17.42 C ANISOU 714 CE MSE A 410 2275 2120 2226 242 -234 125 C ATOM 715 C MSE A 410 31.762 14.285 -29.903 1.00 22.99 C ANISOU 715 C MSE A 410 3085 2788 2861 162 -383 -21 C ATOM 716 O MSE A 410 30.839 14.974 -30.405 1.00 23.49 O ANISOU 716 O MSE A 410 3115 2908 2904 140 -429 26 O ATOM 717 N ILE A 411 32.750 13.711 -30.616 1.00 22.18 N ANISOU 717 N ILE A 411 3009 2728 2689 195 -345 -69 N ATOM 718 CA ILE A 411 32.822 13.744 -32.071 1.00 23.23 C ANISOU 718 CA ILE A 411 3145 2987 2693 196 -344 -80 C ATOM 719 CB ILE A 411 34.201 13.201 -32.577 1.00 24.59 C ANISOU 719 CB ILE A 411 3332 3203 2809 246 -273 -138 C ATOM 720 CG1 ILE A 411 35.271 14.295 -32.388 1.00 26.32 C ANISOU 720 CG1 ILE A 411 3493 3453 3056 263 -219 -38 C ATOM 721 CD1 ILE A 411 36.666 13.790 -32.234 1.00 28.71 C ANISOU 721 CD1 ILE A 411 3775 3761 3371 318 -151 -95 C ATOM 722 CG2 ILE A 411 34.171 12.852 -34.050 1.00 25.93 C ANISOU 722 CG2 ILE A 411 3524 3504 2824 243 -266 -195 C ATOM 723 C ILE A 411 31.610 13.049 -32.705 1.00 23.32 C ANISOU 723 C ILE A 411 3181 3033 2646 153 -406 -158 C ATOM 724 O ILE A 411 31.080 13.526 -33.698 1.00 23.80 O ANISOU 724 O ILE A 411 3225 3207 2611 139 -447 -126 O ATOM 725 N LYS A 412 31.150 11.948 -32.095 1.00 22.39 N ANISOU 725 N LYS A 412 3103 2816 2587 126 -417 -254 N ATOM 726 CA LYS A 412 30.008 11.189 -32.619 1.00 22.44 C ANISOU 726 CA LYS A 412 3126 2844 255.

64. 473 -349 C ATOM 727 CB LYS A 412 30.065 9.720 -32.145 1.00 22.70 C ANISOU 727 CB LYS A 412 3236 2744 264.

43. 450 -472 C ATOM 728 CG LYS A 412 31.201 8.920 -32.768 1.00 22.92 C ANISOU 728 CG LYS A 412 3324 2769 2614 105 -401 -564 C ATOM 729 CD LYS A 412 31.025 8.761 -34.293 1.00 21.99 C ANISOU 729 CD LYS A 412 3210 2800 234.

92. 424 -649 C ATOM 730 CE LYS A 412 32.028 7.811 -34.909 1.00 25.65 C ANISOU 730 CE LYS A 412 3734 3256 2754 152 -367 -778 C ATOM 731 NZ LYS A 412 33.428 8.304 -34.688 1.00 27.17 N ANISOU 731 NZ LYS A 412 3899 3468 2955 246 -293 -708 N ATOM 732 C LYS A 412 28.666 11.875 -32.299 1.00 21.94 C ANISOU 732 C LYS A 412 2995 2803 254.

14. 538 -292 C ATOM 733 O LYS A 412 27.630 11.557 -32.849 1.00 22.69 O

ANISOU 733 O LYS A 412 3067 2958 2597 -40 -599 -352 O

ATOM 734 N ALA A 413 28.709 12.869 -31.427 1.00 21.22 N

ANISOU 734 N ALA A 413 2860 2671 253.

36. 525 -183 N

ATOM 735 CA ALA A 413 27.536 13.650 -31.085 1.00 20.92 C

ANISOU 735 CA ALA A 413 2747 2655 254.

13. 576 -129 C

ATOM 736 CB ALA A 413 27.649 14.219 -29.668 1.00 18.88 C

ANISOU 736 CB ALA A 413 2470 2294 240.

26. 537 -70 C

ATOM 737 C ALA A 413 27.248 14.752 -32.097 1.00 21.86 C

ANISOU 737 C ALA A 413 2818 2897 259.

49. 633 -41 C

ATOM 738 O ALA A 413 26.187 15.379 -32.051 1.00 22.85 O

ANISOU 738 O ALA A 413 2871 3058 275.

48. 693 -4 O

ATOM 739 N VAL A 414 28.175 14.991 -33.014 1.00 22.39 N

ANISOU 739 N VAL A 414 2922 3032 255.

85. 611 -4 N

ATOM 740 CA VAL A 414 27.955 15.974 -34.070 1.00 23.35 C

ANISOU 740 CA VAL A 414 3019 3272 2581 117 -662 98 C

ATOM 741 CB VAL A 414 29.231 16.231 -34.885 1.00 23.82 C

ANISOU 741 CB VAL A 414 3127 3392 2531 144 -600 150 C

ATOM 742 CG1 VAL A 414 28.916 17.030 -36.162 1.00 23.49 C

ANISOU 742 CG1 VAL A 414 3084 3492 2348 165 -656 255 C

ATOM 743 CG2 VAL A 414 30.269 16.960 -34.029 1.00 21.14 C

ANISOU 743 CG2 VAL A 414 2786 2952 2296 164 -520 231 C

ATOM 744 C VAL A 414 26.807 15.533 -34.993 1.00 25.52 C

ANISOU 744 C VAL A 414 3267 3670 276.

90. 761 34 C

ATOM 745 O VAL A 414 26.724 14.372 -35.386 1.00 26.20 O

ANISOU 745 O VAL A 414 3384 3785 278.

46. 766 -102 O

ATOM 746 N ARG A 415 25.914 16.474 -35.297 1.00 26.58 N

ANISOU 746 N ARG A 415 3339 3868 2891 121 -844 127 N

ATOM 747 CA ARG A 415 24.812 16.243 -36.203 1.00 29.14 C

ANISOU 747 CA ARG A 415 3617 4335 3118 109 -958 83 C

ATOM 748 CB ARG A 415 23.449 16.436 -35.494 1.00 29.44 C

ANISOU 748 CB ARG A 415 3545 4355 328.

99. 1027 62 C

ATOM 749 CG ARG A 415 23.141 15.430 -34.381 1.00 29.25 C

ANISOU 749 CG ARG A 415 3504 4222 338.

18. 974 -70 C

ATOM 750 CD ARG A 415 23.007 14.000 -34.895 1.00 29.56 C

ANISOU 750 CD ARG A 415 3579 4300 3352 -70 -985 -236 C

ATOM 751 NE ARG A 415 22.856 13.082 -33.769 1.00 29.80 N

ANISOU 751 NE ARG A 415 3621 4194 3510 -150 -917 -331 N

ATOM 752 CZ ARG A 415 23.825 12.317 -33.266 1.00 28.42 C

ANISOU 752 CZ ARG A 415 3546 3892 3360 -167 -824 -374 C

ATOM 753 NH1 ARG A 415 25.038 12.351 -33.797 1.00 29.21 N

ANISOU 753 NH1 ARG A 415 3727 3996 3374 -111 -782 -347 N

ATOM 754 NH2 ARG A 415 23.574 11.513 -32.230 1.00 25.27 N

ANISOU 754 NH2 ARG A 415 3164 3367 3070 -239 -772 -438 N

ATOM 755 C ARG A 415 24.940 17.199 -37.386 1.00 30.32 C

ANISOU 755 C ARG A 415 3784 4614 3121 172 -1013 223 C

ATOM 756 O ARG A 415 25.119 18.400 -37.205 1.00 30.57 O

ANISOU 756 O ARG A 415 3812 4599 3205 231 -1007 381 O

ATOM 757 N GLY A 416 24.846 16.660 -38.592 1.00 31.60 N

ANISOU 757 N GLY A 416 3973 4936 3096 156 -1066 164 N

ATOM 758 CA GLY A 416 25.049 17.449 -39.795 1.00 32.75 C

ANISOU 758 CA GLY A 416 4156 5224 3063 209 -1110 301 C

ATOM 759 C GLY A 416 26.516 17.725 -40.084 1.00 32.51 C

ANISOU 759 C GLY A 416 4216 5174 2960 216 -984 379 C

ATOM 760 O GLY A 416 27.397 17.335 -39.318 1.00 30.64 O

ANISOU 760 O GLY A 416 4002 4814 2824 191 -871 323 O

ATOM 761 N ASP A 417 26.766 18.388 -41.211 1.00 34.28 N

ANISOU 761 N ASP A 417 4487 5534 3002 249 -1005 511 N

ATOM 762 CA ASP A 417 28.113 18.751 -41.645 1.00 35.22 C

ANISOU 762 CA ASP A 417 4682 5669 3032 244 -879 601 C

ATOM 763 CB ASP A 417 28.165 18.916 -43.173 1.00 37.33 C

ANISOU 763 CB ASP A 417 5008 6157 3018 256 -915 671 C

ATOM 764 CG ASP A 417 28.224 17.574 -43.905 1.00 40.79 C

ANISOU 764 CG ASP A 417 5468 6743 3286 216 -916 453 C

ATOM 765 OD1 ASP A 417 28.476 16.530 -43.243 1.00 40.15 O

ANISOU 765 OD1 ASP A 417 5373 6567 3315 180 -861 264 O

ATOM 766 OD2 ASP A 417 28.023 17.556 -45.146 1.00 44.28 O

ANISOU 766 OD2 ASP A 417 5951 7394 3481 223 -973 470 O

ATOM 767 C ASP A 417 28.588 20.023 -40.949 1.00 34.37 C

ANISOU 767 C ASP A 417 4575 5408 3075 269 -821 788 C

ATOM 768 O ASP A 417 27.782 20.865 -40.553 1.00 33.70 O

ANISOU 768 O ASP A 417 4453 5250 3100 314 -901 893 O

ATOM 769 N LEU A 418 29.902 20.142 -40.795 1.00 34.15 N

ANISOU 769 N LEU A 418 4581 5331 3061 239 -680 814 N

ATOM 770 CA LEU A 418 30.506 21.331 -40.188 1.00 34.32 C

ANISOU 770 CA LEU A 418 4607 5210 3223 240 -613 976 C

ATOM 771 CB LEU A 418 31.439 20.937 -39.032 1.00 32.56 C

ANISOU 771 CB LEU A 418 4354 4852 3167 206 -504 872 C

ATOM 772 CG LEU A 418 30.818 20.136 -37.877 1.00 32.15 C

ANISOU 772 CG LEU A 418 4251 4695 3270 212 -546 713 C

ATOM 773 CD1 LEU A 418 31.869 19.758 -36.847 1.00 32.10 C

ANISOU 773 CD1 LEU A 418 4227 4578 3390 188 -444 632 C

ATOM 774 CD2 LEU A 418 29.674 20.910 -37.221 1.00 32.15 C

ANISOU 774 CD2 LEU A 418 4210 4598 3407 247 -640 782 C

ATOM 775 C LEU A 418 31.217 22.207 -41.237 1.00 36.42 C

ANISOU 775 C LEU A 418 4940 5563 3335 227 -553 1165 C

ATOM 776 O LEU A 418 32.148 21.768 -41.919 1.00 36.22 O

ANISOU 776 O LEU A 418 4945 5656 3162 188 -454 1130 O

ATOM 777 N ASN A 419 30.740 23.444 -41.374 1.00 38.22 N

ANISOU 777 N ASN A 419 5193 5731 3598 263 -611 1367 N

ATOM 778 CA ASN A 419 31.215 24.360 -42.413 1.00 40.94 C

ANISOU 778 CA ASN A 419 5619 6147 3791 250 -570 1584 C

ATOM 779 CB ASN A 419 30.272 24.322 -43.627 1.00 42.84 C

ANISOU 779 CB ASN A 419 5901 6577 3800 306 -702 1654 C

ATOM 780 CG ASN A 419 30.365 23.011 -44.413 1.00 43.28 C

ANISOU 780 CG ASN A 419 5958 6853 3634 281 -699 1469 C

ATOM 781 OD1 ASN A 419 31.429 22.652 -44.933 1.00 42.07 O

ANISOU 781 OD1 ASN A 419 5839 6798 3349 224 -567 1436 O

ATOM 782 ND2 ASN A 419 29.243 22.307 -44.522 1.00 41.71 N

ANISOU 782 ND2 ASN A 419 5716 6735 3396 320 -841 1339 N

ATOM 783 C ASN A 419 31.355 25.811 -41.928 1.00 41.80 C

ANISOU 783 C ASN A 419 5754 6059 4070 255 -549 1788 C

ATOM 784 O ASN A 419 31.184 26.739 -42.727 1.00 43.13 O

ANISOU 784 O ASN A 419 5997 6247 4142 277 -579 2006 O

ATOM 785 N PHE A 420 31.654 25.990 -40.633 1.00 40.43 N

ANISOU 785 N PHE A 420 5526 5694 4142 235 -501 1717 N

ATOM 786 CA PHE A 420 31.813 27.317 -40.017 1.00 41.44 C

ANISOU 786 CA PHE A 420 5674 5609 4463 231 -477 1867 C

ATOM 787 CB PHE A 420 31.969 27.229 -38.484 1.00 38.75 C

ANISOU 787 CB PHE A 420 5258 5093 4371 217 -448 1720 C

ATOM 788 CG PHE A 420 30.717 26.787 -37.763 1.00 38.53 C

ANISOU 788 CG PHE A 420 5167 5033 4438 296 -567 1596 C

ATOM 789 CD1 PHE A 420 30.638 25.508 -37.189 1.00 35.77 C

ANISOU 789 CD1 PHE A 420 4757 4741 4094 283 -566 1382 C

ATOM 790 CE1 PHE A 420 29.480 25.098 -36.517 1.00 35.30 C

ANISOU 790 CE1 PHE A 420 4636 4656 4121 336 -660 1273 C

ATOM 791 CZ PHE A 420 28.390 25.961 -36.410 1.00 36.31 C

ANISOU 791 CZ PHE A 420 4745 4716 4335 416 -759 1362 C

ATOM 792 CE2 PHE A 420 28.453 27.236 -36.976 1.00 37.91 C

ANISOU 792 CE2 PHE A 420 5009 4854 4542 452 -773 1570 C

ATOM 793 CD2 PHE A 420 29.615 27.647 -37.648 1.00 38.57 C

ANISOU 793 CD2 PHE A 420 5173 4948 4536 385 -676 1694 C

ATOM 794 C PHE A 420 32.985 28.099 -40.621 1.00 43.58 C

ANISOU 794 C PHE A 420 6013 5871 4673 144 -345 2038 C

ATOM 795 O PHE A 420 34.016 27.544 -40.971 1.00 43.69 O

ANISOU 795 O PHE A 420 6017 6000 458.

67. 227 1979 O

ATOM 796 N VAL A 421 32.815 29.402 -40.734 1.00 46.01 N

ANISOU 796 N VAL A 421 6388 6035 5060 155 -361 2250 N

ATOM 797 CA VAL A 421 33.827 30.281 -41.275 1.00 48.42 C

ANISOU 797 CA VAL A 421 6767 6301 533.

58. 235 2439 C

ATOM 798 CB VAL A 421 33.415 30.657 -42.715 1.00 50.72 C

ANISOU 798 CB VAL A 421 7168 6727 537.

95. 285 2662 C

ATOM 799 CG1 VAL A 421 33.405 32.139 -42.946 1.00 53.63 C

ANISOU 799 CG1 VAL A 421 7644 6908 582.

89. 278 2939 C

ATOM 800 CG2 VAL A 421 34.260 29.882 -43.738 1.00 50.83 C

ANISOU 800 CG2 VAL A 421 7196 6999 511.

16. 175 2634 C

ATOM 801 C VAL A 421 33.969 31.474 -40.304 1.00 49.05 C

ANISOU 801 C VAL A 421 6856 6092 569.

35. 213 2513 C

ATOM 802 O VAL A 421 33.147 31.634 -39.405 1.00 48.40 O

ANISOU 802 O VAL A 421 6734 5873 5784 117 -308 2435 O

ATOM 803 N ASN A 422 35.019 32.281 -40.431 1.00 50.78 N

ANISOU 803 N ASN A 422 7118 6220 5956 -86 -79 2641 N

ATOM 804 CA ASN A 422 35.104 33.500 -39.619 1.00 51.41 C

ANISOU 804 CA ASN A 422 7224 6012 6298 -114 -65 2718 C

ATOM 805 CB ASN A 422 36.417 33.548 -38.825 1.00 50.54 C

ANISOU 805 CB ASN A 422 7039 5832 6330 -263 80 2603 C

ATOM 806 CG ASN A 422 37.651 33.599 -39.710 1.00 53.01 C

ANISOU 806 CG ASN A 422 7370 6272 6500 -410 242 2706 C

ATOM 807 OD1 ASN A 422 38.708 33.120 -39.316 1.00 54.15 O

ANISOU 807 OD1 ASN A 422 7415 6486 6672 -510 351 2564 O

ATOM 808 ND2 ASN A 422 37.536 34.195 -40.891 1.00 54.93 N

ANISOU 808 ND2 ASN A 422 7734 6550 6586 -424 260 2956 N

ATOM 809 C ASN A 422 34.855 34.791 -40.412 1.00 54.51 C

ANISOU 809 C ASN A 422 7760 6272 6679 -107 -77 3020 C

ATOM 810 O ASN A 422 34.565 34.742 -41.619 1.00 55.83 O

ANISOU 810 O ASN A 422 8008 6590 6613 -71 -108 3185 O

ATOM 811 N ARG A 423 34.971 35.936 -39.726 1.00 55.63 N

ANISOU 811 N ARG A 423 7940 6128 7070 -139 -56 3090 N

ATOM 812 CA ARG A 423 34.778 37.275 -40.329 1.00 58.60 C

ANISOU 812 CA ARG A 423 8467 6310 7489 -134 -63 3384 C

ATOM 813 CB ARG A 423 35.154 38.368 -39.309 1.00 59.00 C

ANISOU 813 CB ARG A 423 8531 6029 7855 -205 -10 3374 C

ATOM 814 CG ARG A 423 35.137 39.808 -39.824 1.00 63.01 C

ANISOU 814 CG ARG A 423 9207 6282 8454 -228 9 3672 C

ATOM 815 CD ARG A 423 35.119 40.813 -38.669 1.00 63.11 C

ANISOU 815 CD ARG A 423 9229 5943 8808 -243 11 3608 C

ATOM 816 NE ARG A 423 35.372 42.173 -39.147 1.00 69.55 N

ANISOU 816 NE ARG A 423 10211 6488 9728 -310 65 3886 N

ATOM 817 CZ ARG A 423 35.212 43.291 -38.432 1.00 71.04 C

ANISOU 817 CZ ARG A 423 10463 6323 10208 -303 54 3903 C

ATOM 818 NH1 ARG A 423 34.780 43.251 -37.173 1.00 69.69 N

ANISOU 818 NH1 ARG A 423 10195 6035 10247 -226 -8 3649 N

ATOM 819 NH2 ARG A 423 35.491 44.463 -38.983 1.00 73.29 N

ANISOU 819 NH2 ARG A 423 10914 6362 10570 -377 112 4175 N

ATOM 820 C ARG A 423 35.554 37.441 -41.644 1.00 60.66 C

ANISOU 820 C ARG A 423 8824 6708 7516 -250 52 3610 C

ATOM 821 O ARG A 423 34.991 37.878 -42.656 1.00 63.13 O

ANISOU 821 O ARG A 423 9263 7049 7676 -176 -13 3852 O

ATOM 822 N ALA A 424 36.833 37.059 -41.619 1.00 60.09 N

ANISOU 822 N ALA A 424 8685 6740 7406 -424 220 3525 N

ATOM 823 CA ALA A 424 37.733 37.087 -42.782 1.00 61.86 C

ANISOU 823 CA ALA A 424 8968 7132 7403 -560 366 3695 C

ATOM 824 CB ALA A 424 39.184 37.099 -42.313 1.00 61.84 C

ANISOU 824 CB ALA A 424 8869 7119 7507 -766 558 3590 C

ATOM 825 C ALA A 424 37.525 35.953 -43.803 1.00 61.47 C

ANISOU 825 C ALA A 424 8907 7435 7014 -498 342 3661 C

ATOM 826 O ALA A 424 38.302 35.834 -44.758 1.00 63.06 O

ANISOU 826 O ALA A 424 9142 7818 7001 -608 476 3765 O

ATOM 827 N ASN A 425 36.503 35.117 -43.583 1.00 59.19 N

ANISOU 827 N ASN A 425 8565 7245 6681 -334 181 3501 N

ATOM 828 CA ASN A 425 36.066 34.070 -44.533 1.00 58.70 C

ANISOU 828 CA ASN A 425 8501 7493 6310 -257 119 3455 C

ATOM 829 CB ASN A 425 35.834 34.650 -45.946 1.00 61.60 C

ANISOU 829 CB ASN A 425 9027 7961 6417 -245 108 3760 C

ATOM 830 CG ASN A 425 35.025 33.719 -46.851 1.00 61.89 C

ANISOU 830 CG ASN A 425 9073 8290 6153 -127 -18 3714 C

ATOM 831 OD1 ASN A 425 34.099 33.032 -46.410 1.00 60.11 O

ANISOU 831 OD1 ASN A 425 8770 8100 5969 -2 -169 3531 O

ATOM 832 ND2 ASN A 425 35.377 33.700 -48.125 1.00 65.09 N

ANISOU 832 ND2 ASN A 425 9572 8911 6249 -176 49 3875 N

ATOM 833 C ASN A 425 36.992 32.848 -44.543 1.00 56.85 C

ANISOU 833 C ASN A 425 8150 7489 5962 -338 240 3221 C

ATOM 834 O ASN A 425 37.088 32.101 -45.516 1.00 57.64 O

ANISOU 834 O ASN A 425 8263 7855 5782 -333 263 3202 O

ATOM 835 N GLN A 426 37.662 32.653 -43.424 1.00 54.65 N

ANISOU 835 N GLN A 426 7757 7103 5906 -403 310 3033 N

ATOM 836 CA GLN A 426 38.574 31.539 -43.259 1.00 52.90 C

ANISOU 836 CA GLN A 426 7412 7061 5626 -461 416 2803 C

ATOM 837 CB GLN A 426 39.823 31.999 -42.501 1.00 53.02 C

ANISOU 837 CB GLN A 426 7345 6954 5845 -609 567 2761 C

ATOM 838 CG GLN A 426 40.496 33.214 -43.170 1.00 57.14 C

ANISOU 838 CG GLN A 426 7957 7403 6350 -755 700 3030 C

ATOM 839 CD GLN A 426 41.953 33.340 -42.795 1.00 59.04 C

ANISOU 839 CD GLN A 426 8085 7648 6699 -930 886 2958 C

ATOM 840 OE1 GLN A 426 42.294 33.478 -41.614 1.00 58.44 O

ANISOU 840 OE1 GLN A 426 7913 7417 6874 -964 882 2816 O

ATOM 841 NE2 GLN A 426 42.825 33.277 -43.793 1.00 60.49 N

ANISOU 841 NE2 GLN A 426 8269 8028 6687 -1044 1051 3047 N

ATOM 842 C GLN A 426 37.859 30.413 -42.543 1.00 49.11 C

ANISOU 842 C GLN A 426 6847 6621 5192 -339 290 2547 C

ATOM 843 O GLN A 426 37.235 30.626 -41.508 1.00 47.36 O

ANISOU 843 O GLN A 426 6597 6214 5183 -278 192 2479 O

ATOM 844 N ARG A 427 37.920 29.226 -43.133 1.00 48.00 N

ANISOU 844 N ARG A 427 6674 6721 4843 -307 298 2408 N

ATOM 845 CA ARG A 427 37.341 28.025 -42.550 1.00 45.29 C

ANISOU 845 CA ARG A 427 6256 6425 4525 -212 198 2160 C

ATOM 846 CB ARG A 427 37.621 26.831 -43.471 1.00 45.82 C

ANISOU 846 CB ARG A 427 6312 6763 4335 -202 242 2034 C

ATOM 847 CG ARG A 427 37.173 25.507 -42.909 1.00 43.52 C

ANISOU 847 CG ARG A 427 5952 6510 4074 -124 162 1771 C

ATOM 848 CD ARG A 427 37.185 24.344 -43.919 1.00 44.50 C

ANISOU 848 CD ARG A 427 6088 6884 3937 -97 174 1641 C

ATOM 849 NE ARG A 427 36.589 23.168 -43.281 1.00 42.09 N

ANISOU 849 NE ARG A 427 5732 6558 3701 -26 80 1406 N

ATOM 850 CZ ARG A 427 35.305 22.813 -43.382 1.00 41.80 C

ANISOU 850 CZ ARG A 427 5721 6535 362.

43. 78 1366 C

ATOM 851 NH1 ARG A 427 34.472 23.522 -44.138 1.00 40.53 N

ANISOU 851 NH1 ARG A 427 5630 6425 3343.

70. 173 1541 N

ATOM 852 NH2 ARG A 427 34.859 21.734 -42.737 1.00 38.54 N

ANISOU 852 NH2 ARG A 427 5262 6088 329.

83. 141 1153 N

ATOM 853 C ARG A 427 37.941 27.795 -41.156 1.00 42.92 C

ANISOU 853 C ARG A 427 5846 5984 4476 -242 239 1985 C

ATOM 854 O ARG A 427 39.158 27.682 -41.033 1.00 43.19 O

ANISOU 854 O ARG A 427 5815 6060 4536 -330 378 1932 O

ATOM 855 N LEU A 428 37.109 27.762 -40.111 1.00 40.68 N

ANISOU 855 N LEU A 428 5537 5548 4373 -169 120 1900 N

ATOM 856 CA LEU A 428 37.620 27.491 -38.771 1.00 38.47 C

ANISOU 856 CA LEU A 428 5162 5153 4302 -189 146 1733 C

ATOM 857 CB LEU A 428 36.507 27.485 -37.706 1.00 37.16 C

ANISOU 857 CB LEU A 428 4983 4836 4300 -103 12 1656 C

ATOM 858 CG LEU A 428 35.520 28.644 -37.563 1.00 38.47 C

ANISOU 858 CG LEU A 428 5210 4834 4572 -57 -80 1807 C

ATOM 859 CD1 LEU A 428 34.640 28.465 -36.331 1.00 36.49 C

ANISOU 859 CD1 LEU A 428 4911 4461 4493.

17. 177 1674 C

ATOM 860 CD2 LEU A 428 36.231 29.983 -37.520 1.00 40.33 C

ANISOU 860 CD2 LEU A 428 5484 4917 4922 -147 4 1968 C

ATOM 861 C LEU A 428 38.327 26.130 -38.791 1.00 37.36 C

ANISOU 861 C LEU A 428 4947 5175 4073 -187 206 1533 C ATOM 862 O LEU A 428 37.927 25.217 -39.528 1.00 37.44 O ANISOU 862 O LEU A 428 4980 5342 3905 -134 173 1466 O ATOM 863 N ASN A 429 39.393 26.000 -38.005 1.00 36.22 N ANISOU 863 N ASN A 429 4713 4996 4055 -240 291 1432 N ATOM 864 CA ASN A 429 40.027 24.699 -37.838 1.00 35.15 C ANISOU 864 CA ASN A 429 4501 4981 3874 -209 331 1232 C ATOM 865 CB ASN A 429 41.422 24.797 -37.154 1.00 35.29 C ANISOU 865 CB ASN A 429 4406 4986 4018 -278 438 1162 C ATOM 866 CG ASN A 429 41.376 25.137 -35.654 1.00 34.45 C ANISOU 866 CG ASN A 429 4253 4696 4142 -277 377 1100 C ATOM 867 OD1 ASN A 429 40.351 25.025 -34.971 1.00 33.81 O ANISOU 867 OD1 ASN A 429 4210 4506 4130 -211 263 1066 O ATOM 868 ND2 ASN A 429 42.531 25.532 -35.132 1.00 32.90 N ANISOU 868 ND2 ASN A 429 3961 4484 4057 -356 458 1073 N ATOM 869 C ASN A 429 39.062 23.680 -37.199 1.00 32.57 C ANISOU 869 C ASN A 429 4181 4618 3577 -107 207 1081 C ATOM 870 O ASN A 429 38.051 24.074 -36.619 1.00 31.85 O ANISOU 870 O ASN A 429 4121 4399 3582 -74 105 1113 O ATOM 871 N PRO A 430 39.325 22.378 -37.376 1.00 31.96 N ANISOU 871 N PRO A 430 4076 4654 3413 -60 223 919 N ATOM 872 CA PRO A 430 38.489 21.306 -36.827 1.00 30.42 C ANISOU 872 CA PRO A 430 3895 4422 3243 19 122 773 C ATOM 873 CB PRO A 430 39.374 20.073 -36.998 1.00 30.52 C ANISOU 873 CB PRO A 430 3865 4539 3194 51 191 608 C ATOM 874 CG PRO A 430 40.115 20.354 -38.256 1.00 32.63 C ANISOU 874 CG PRO A 430 4130 4972 3296 8 302 673 C ATOM 875 CD PRO A 430 40.439 21.822 -38.174 1.00 33.57 C ANISOU 875 CD PRO A 430 4239 5029 3487 -78 346 859 C ATOM 876 C PRO A 430 38.030 21.452 -35.362 1.00 28.84 C ANISOU 876 C PRO A 430 3672 4045 3243 38 48 733 C ATOM 877 O PRO A 430 36.844 21.250 -35.072 1.00 28.54 O ANISOU 877 O PRO A 430 3669 3949 322.

76. 51 715 O ATOM 878 N MSE A 431 38.938 21.798 -34.454 1.00 27.42 N ANISOU 878 N MSE A 431 3425 3793 3198 8 97 713 N ATOM 879 CA MSE A 431 38.573 21.963 -33.044 1.00 25.88 C ANISOU 879 CA MSE A 431 3213 3450 3172 23 33 670 C ATOM 880 CB MSE A 431 39.832 22.116 -32.159 1.00 25.62 C ANISOU 880 CB MSE A 431 3094 3390 3252 -8 89 615 C ATOM 881 CG MSE A 431 40.705 20.833 -32.079 1.00 26.44 C ANISOU 881 CG MSE A 431 3147 3586 3315 45 124 475 C ATOM 882 SE MSE A 431 39.842 19.246 -31.234 0.90 30.28 SE ANISOU 882 SE MSE A 431 3685 4010 3809 150 26 327 SE ATOM 883 CE MSE A 431 39.652 20.084 -29.473 1.00 25.02 C ANISOU 883 CE MSE A 431 2993 3190 3324 126 -33 340 C ATOM 884 C MSE A 431 37.575 23.100 -32.781 1.00 25.36 C ANISOU 884 C MSE A 431 3187 3264 318.

9. 30 783 C ATOM 885 O MSE A 431 36.673 22.960 -31.939 1.00 24.38 O ANISOU 885 O MSE A 431 3073 3052 314.

47. 107 735 O ATOM 886 N HIS A 432 37.743 24.212 -33.483 1.00 26.43 N ANISOU 886 N HIS A 432 3345 3391 3306 -42 7 933 N ATOM 887 CA HIS A 432 36.804 25.342 -33.406 1.00 27.85 C ANISOU 887 CA HIS A 432 3573 3450 3560 -37 -53 1055 C ATOM 888 CB HIS A 432 37.483 26.636 -33.864 1.00 29.15 C ANISOU 888 CB HIS A 432 3755 3560 3759 -119 20 1213 C ATOM 889 CG HIS A 432 38.458 27.164 -32.859 1.00 31.05 C ANISOU 889 CG HIS A 432 3933 3702 4163 -191 77 1164 C ATOM 890 ND1 HIS A 432 39.711 26.614 -32.671 1.00 31.07 N ANISOU 890 ND1 HIS A 432 3853 3795 4157 -238 156 1070 N ATOM 891 CE1 HIS A 432 40.338 27.277 -31.714 1.00 33.02 C ANISOU 891 CE1 HIS A 432 4046 3937 4562 -300 177 1035 C ATOM 892 NE2 HIS A 432 39.529 28.221 -31.255 1.00 32.01 N ANISOU 892 NE2 HIS A 432 3972 3642 4547 -295 121 1094 N ATOM 893 CD2 HIS A 432 38.348 28.170 -31.956 1.00 32.70 C

ANISOU 893 CD2 HIS A 432 4141 3736 4548 -220 58 1179 C

ATOM 894 C HIS A 432 35.510 25.078 -34.165 1.00 27.83 C

ANISOU 894 C HIS A 432 3625 3502 3447 29 -143 1098 C

ATOM 895 O HIS A 432 34.466 25.587 -33.800 1.00 28.93 O

ANISOU 895 O HIS A 432 3780 3549 3665 73 -223 1134 O

ATOM 896 N GLN A 433 35.608 24.283 -35.217 1.00 28.16 N

ANISOU 896 N GLN A 433 3686 3705 3308 38 -128 1081 N

ATOM 897 CA GLN A 433 34.467 23.712 -35.940 1.00 29.30 C

ANISOU 897 CA GLN A 433 3866 3942 3324 95 -220 1070 C

ATOM 898 CB GLN A 433 35.053 22.746 -36.985 1.00 30.36 C

ANISOU 898 CB GLN A 433 4014 4260 3263 84 -165 1008 C

ATOM 899 CG GLN A 433 34.400 22.595 -38.320 1.00 34.65 C

ANISOU 899 CG GLN A 433 4611 4954 3599 106 -217 1065 C

ATOM 900 CD GLN A 433 34.134 23.881 -39.054 1.00 37.03 C

ANISOU 900 CD GLN A 433 4967 5253 3848 101 -235 1288 C

ATOM 901 OE1 GLN A 433 32.987 24.307 -39.137 1.00 38.30 O

ANISOU 901 OE1 GLN A 433 5148 5383 4022 154 -351 1359 O

ATOM 902 NE2 GLN A 433 35.176 24.486 -39.632 1.00 38.30 N

ANISOU 902 NE2 GLN A 433 5153 5454 3945 38 -121 1405 N

ATOM 903 C GLN A 433 33.551 22.973 -34.938 1.00 27.21 C

ANISOU 903 C GLN A 433 3569 3614 3155 140 -301 930 C

ATOM 904 O GLN A 433 32.367 23.270 -34.843 1.00 26.79 O

ANISOU 904 O GLN A 433 3518 3526 3136 182 -393 960 O

ATOM 905 N LEU A 434 34.134 22.047 -34.166 1.00 25.47 N

ANISOU 905 N LEU A 434 3317 3379 2983 132 -261 785 N

ATOM 906 CA LEU A 434 33.444 21.324 -33.076 1.00 23.90 C

ANISOU 906 CA LEU A 434 3095 3107 2877 157 -313 662 C

ATOM 907 CB LEU A 434 34.364 20.255 -32.466 1.00 21.96 C

ANISOU 907 CB LEU A 434 2834 2862 2649 154 -258 530 C

ATOM 908 CG LEU A 434 34.764 19.139 -33.439 1.00 23.59 C

ANISOU 908 CG LEU A 434 3064 3192 2709 164 -230 450 C

ATOM 909 CD1 LEU A 434 35.976 18.335 -32.918 1.00 20.60 C

ANISOU 909 CD1 LEU A 434 2659 2806 2361 179 -162 347 C

ATOM 910 CD2 LEU A 434 33.550 18.247 -33.779 1.00 19.71 C

ANISOU 910 CD2 LEU A 434 2602 2734 2153 179 -308 372 C

ATOM 911 C LEU A 434 32.955 22.243 -31.952 1.00 23.68 C

ANISOU 911 C LEU A 434 3044 2938 3017 164 -342 696 C

ATOM 912 O LEU A 434 31.826 22.090 -31.488 1.00 22.82 O

ANISOU 912 O LEU A 434 2922 2795 2954 191 -409 658 O

ATOM 913 N LEU A 435 33.830 23.153 -31.512 1.00 23.88 N

ANISOU 913 N LEU A 435 3056 2886 3130 132 -286 752 N

ATOM 914 CA LEU A 435 33.499 24.163 -30.507 1.00 25.30 C

ANISOU 914 CA LEU A 435 3221 2926 3468 134 -304 776 C

ATOM 915 CB LEU A 435 34.675 25.123 -30.289 1.00 25.47 C

ANISOU 915 CB LEU A 435 3231 2880 3567 76 -233 832 C

ATOM 916 CG LEU A 435 34.639 26.078 -29.094 1.00 25.12 C

ANISOU 916 CG LEU A 435 3169 2684 3693 62 -237 814 C

ATOM 917 CD1 LEU A 435 34.703 25.341 -27.754 1.00 24.17 C

ANISOU 917 CD1 LEU A 435 3012 2549 3622 73 -247 664 C

ATOM 918 CD2 LEU A 435 35.784 27.023 -29.203 1.00 25.51 C

ANISOU 918 CD2 LEU A 435 3211 2680 3803 -167 880 C

ATOM 919 C LEU A 435 32.245 24.976 -30.853 1.00 27.05 C

ANISOU 919 C LEU A 435 3458 3104 3717 181 -377 868 C

ATOM 920 O LEU A 435 31.290 25.013 -30.067 1.00 27.13 O

ANISOU 920 O LEU A 435 3441 3056 3810 219 -426 813 O

ATOM 921 N ARG A 436 32.256 25.645 -32.008 1.00 29.13 N

ANISOU 921 N ARG A 436 3760 3400 3908 183 -382 1011 N

ATOM 922 CA ARG A 436 31.117 26.464 -32.400 1.00 30.76 C

ANISOU 922 CA ARG A 436 3982 3566 4140 248 -463 1117 C

ATOM 923 CB ARG A 436 31.376 27.299 -33.659 1.00 33.08 C

ANISOU 923 CB ARG A 436 4340 3883 4346 244 -457 1307 C

ATOM 924 CG ARG A 436 32.474 28.404 -33.560 1.00 40.00 C

ANISOU 924 CG ARG A 436 5252 4636 5311 174 -367 1413 C

ATOM 925 CD ARG A 436 32.607 29.153 -32.189 1.00 47.23 C

ANISOU 925 CD ARG A 436 6140 5358 6447 160 -347 1351 C

ATOM 926 NE ARG A 436 34.019 29.442 -31.860 1.00 51.94 N

ANISOU 926 NE ARG A 436 6729 5911 7097 53 -242 1339 N

ATOM 927 CZ ARG A 436 34.460 30.070 -30.761 1.00 55.22 C

ANISOU 927 CZ ARG A 436 7119 6181 7681 10 -211 1275 C

ATOM 928 NH1 ARG A 436 33.623 30.495 -29.823 1.00 56.84 N

ANISOU 928 NH1 ARG A 436 7313 6263 8019 70 -265 1212 N

ATOM 929 NH2 ARG A 436 35.766 30.280 -30.592 1.00 56.92 N

ANISOU 929 NH2 ARG A 436 7311 6387 7930 -96 -122 1262 N

ATOM 930 C ARG A 436 29.860 25.608 -32.560 1.00 29.85 C

ANISOU 930 C ARG A 436 3833 3546 3961 304 -554 1040 C

ATOM 931 O ARG A 436 28.781 26.041 -32.179 1.00 29.79 O

ANISOU 931 O ARG A 436 3791 3486 4041 365 -622 1042 O

ATOM 932 N HIS A 437 30.000 24.397 -33.106 1.00 28.56 N

ANISOU 932 N HIS A 437 3672 3522 3657 280 -551 961 N

ATOM 933 CA HIS A 437 28.855 23.524 -33.256 1.00 27.62 C

ANISOU 933 CA HIS A 437 3517 3491 3485 308 -633 872 C

ATOM 934 CB HIS A 437 29.238 22.173 -33.872 1.00 26.97 C

ANISOU 934 CB HIS A 437 3455 3538 3253 269 -613 771 C

ATOM 935 CG HIS A 437 28.094 21.203 -33.939 1.00 24.96 C

ANISOU 935 CG HIS A 437 3163 3358 2963 273 -691 657 C

ATOM 936 ND1 HIS A 437 27.096 21.289 -34.889 1.00 23.43 N

ANISOU 936 ND1 HIS A 437 2950 3277 2675 305 -793 694 N

ATOM 937 CE1 HIS A 437 26.222 20.315 -34.704 1.00 23.02 C

ANISOU 937 CE1 HIS A 437 2852 3273 2623 283 -843 560 C

ATOM 938 NE2 HIS A 437 26.611 19.602 -33.660 1.00 24.74 N

ANISOU 938 NE2 HIS A 437 3071 3399 2929 238 -771 453 N

ATOM 939 CD2 HIS A 437 27.787 20.134 -33.169 1.00 22.63 C

ANISOU 939 CD2 HIS A 437 2844 3039 2717 240 -683 510 C

ATOM 940 C HIS A 437 28.175 23.327 -31.894 1.00 26.83 C

ANISOU 940 C HIS A 437 3359 3302 3534 317 -643 763 C

ATOM 941 O HIS A 437 26.971 23.545 -31.765 1.00 27.43 O

ANISOU 941 O HIS A 437 3383 3382 3658 363 -717 757 O

ATOM 942 N PHE A 438 28.958 22.972 -30.878 1.00 25.29 N

ANISOU 942 N PHE A 438 3167 3035 3407 276 -569 682 N

ATOM 943 CA PHE A 438 28.394 22.684 -29.559 1.00 24.57 C

ANISOU 943 CA PHE A 438 3034 2877 3426 274 -566 579 C

ATOM 944 CB PHE A 438 29.261 21.668 -28.812 1.00 22.50 C

ANISOU 944 CB PHE A 438 2794 2601 3155 227 -502 477 C

ATOM 945 CG PHE A 438 29.231 20.302 -29.427 1.00 20.80 C

ANISOU 945 CG PHE A 438 2601 2477 2826 203 -510 405 C

ATOM 946 CD1 PHE A 438 28.021 19.574 -29.486 1.00 20.00 C

ANISOU 946 CD1 PHE A 438 2472 2420 2708 192 -562 337 C

ATOM 947 CE1 PHE A 438 27.970 18.314 -30.056 1.00 18.22 C

ANISOU 947 CE1 PHE A 438 2274 2260 2389 160 -571 256 C

ATOM 948 CZ PHE A 438 29.155 17.745 -30.605 1.00 20.73 C

ANISOU 948 CZ PHE A 438 2649 2605 2624 156 -525 238 C

ATOM 949 CE2 PHE A 438 30.357 18.468 -30.569 1.00 17.04 C

ANISOU 949 CE2 PHE A 438 2194 2113 2167 174 -469 308 C

ATOM 950 CD2 PHE A 438 30.383 19.739 -29.965 1.00 19.46 C

ANISOU 950 CD2 PHE A 438 2473 2349 2573 188 -464 392 C

ATOM 951 C PHE A 438 28.046 23.929 -28.731 1.00 25.24 C

ANISOU 951 C PHE A 438 3090 2842 3658 311 -567 615 C

ATOM 952 O PHE A 438 27.189 23.875 -27.871 1.00 24.41 O

ANISOU 952 O PHE A 438 2936 2710 3630 328 -580 543 O

ATOM 953 N GLN A 439 28.691 25.057 -29.040 1.00 27.21 N

ANISOU 953 N GLN A 439 3372 3021 3947 320 -548 723 N

ATOM 954 CA GLN A 439 28.316 26.353 -28.476 1.00 28.57 C

ANISOU 954 CA GLN A 439 3530 3062 4264 365 -557 766 C

ATOM 955 CB GLN A 439 29.395 27.400 -28.724 1.00 29.66 C

ANISOU 955 CB GLN A 439 3721 3102 4446 335 -509 870 C

ATOM 956 CG GLN A 439 30.531 27.306 -27.690 1.00 30.49 C

ANISOU 956 CG GLN A 439 3826 3151 4608 264 -433 781 C

ATOM 957 CD GLN A 439 31.679 28.234 -27.997 1.00 34.96 C

ANISOU 957 CD GLN A 439 4429 3638 5214 207 -379 871 C

ATOM 958 OE1 GLN A 439 31.762 28.782 -29.090 1.00 38.23 O

ANISOU 958 OE1 GLN A 439 4884 4053 5587 208 -383 1013 O

ATOM 959 NE2 GLN A 439 32.570 28.423 -27.029 1.00 35.77 N

ANISOU 959 NE2 GLN A 439 4515 3679 5395 149 -329 791 N

ATOM 960 C GLN A 439 26.934 26.813 -28.925 1.00 29.99 C

ANISOU 960 C GLN A 439 3669 3257 4470 454 -644 815 C

ATOM 961 O GLN A 439 26.223 27.399 -28.120 1.00 30.12 O

ANISOU 961 O GLN A 439 3639 3192 4612 505 -655 772 O

ATOM 962 N LYS A 440 26.528 26.494 -30.162 1.00 31.18 N

ANISOU 962 N LYS A 440 3825 3525 4496 477 -708 887 N

ATOM 963 CA LYS A 440 25.142 26.739 -30.603 1.00 33.51 C

ANISOU 963 CA LYS A 440 4058 3873 4799 568 -811 916 C

ATOM 964 CB LYS A 440 24.983 26.655 -32.140 1.00 35.28 C

ANISOU 964 CB LYS A 440 4316 4227 4864 593 -887 1034 C

ATOM 965 CG LYS A 440 25.813 27.704 -32.903 1.00 37.77 C

ANISOU 965 CG LYS A 440 4728 4471 5152 603 -867 1220 C

ATOM 966 CD LYS A 440 25.401 27.909 -34.364 1.00 39.08 C

ANISOU 966 CD LYS A 440 4927 4756 5164 659 -961 1367 C

ATOM 967 CE LYS A 440 26.117 29.152 -34.913 1.00 43.76 C

ANISOU 967 CE LYS A 440 5623 5235 5768 670 -931 1574 C

ATOM 968 NZ LYS A 440 25.782 29.513 -36.329 1.00 47.40 N

ANISOU 968 NZ LYS A 440 6140 5801 6067 730 -1019 1756 N

ATOM 969 C LYS A 440 24.114 25.822 -29.905 1.00 32.70 C

ANISOU 969 C LYS A 440 3858 3844 4721 562 -831 761 C

ATOM 970 O LYS A 440 23.029 26.285 -29.495 1.00 33.55 O

ANISOU 970 O LYS A 440 3882 3936 4931 635 -876 735 O

ATOM 971 N ASP A 441 24.440 24.539 -29.780 1.00 30.72 N

ANISOU 971 N ASP A 441 3617 3671 4384 475 -794 659 N

ATOM 972 CA ASP A 441 23.533 23.580 -29.155 1.00 30.83 C

ANISOU 972 CA ASP A 441 3554 3747 4415 443 -800 522 C

ATOM 973 CB ASP A 441 22.400 23.160 -30.119 1.00 33.58 C

ANISOU 973 CB ASP A 441 3830 4241 4688 466 -905 515 C

ATOM 974 CG ASP A 441 21.496 22.044 -29.536 1.00 36.33 C

ANISOU 974 CG ASP A 441 4094 4658 5053 398 -900 365 C

ATOM 975 OD1 ASP A 441 20.945 22.224 -28.422 1.00 37.04 O

ANISOU 975 OD1 ASP A 441 4116 4697 5259 402 -859 301 O

ATOM 976 OD2 ASP A 441 21.344 20.987 -30.206 1.00 39.15 O

ANISOU 976 OD2 ASP A 441 4455 5117 5303 335 -932 308 O

ATOM 977 C ASP A 441 24.280 22.357 -28.620 1.00 28.33 C

ANISOU 977 C ASP A 441 3285 3430 4047 345 -724 424 C

ATOM 978 O ASP A 441 24.976 21.649 -29.360 1.00 27.35 O

ANISOU 978 O ASP A 441 3222 3360 3809 305 -718 428 O

ATOM 979 N ALA A 442 24.125 22.122 -27.320 1.00 26.96 N

ANISOU 979 N ALA A 442 3088 3198 3956 316 -666 338 N

ATOM 980 CA ALA A 442 24.818 21.037 -26.645 1.00 24.82 C

ANISOU 980 CA ALA A 442 2872 2908 3650 240 -598 261 C

ATOM 981 CB ALA A 442 25.668 21.599 -25.523 1.00 23.21 C

ANISOU 981 CB ALA A 442 2703 2600 3517 243 -531 259 C

ATOM 982 C ALA A 442 23.960 19.870 -26.145 1.00 24.67 C

ANISOU 982 C ALA A 442 2817 2932 3624 175 -587 156 C

ATOM 983 O ALA A 442 24.488 19.030 -25.378 1.00 25.14 O

ANISOU 983 O ALA A 442 2932 2949 3670 120 -527 105 O

ATOM 984 N LYS A 443 22.691 19.779 -26.585 1.00 24.95 N

ANISOU 984 N LYS A 443 2761 3052 3668 177 -646 129 N

ATOM 985 CA LYS A 443 21.742 18.689 -26.217 1.00 25.03 C

ANISOU 985 CA LYS A 443 2718 3111 3680 93 -634 28 C

ATOM 986 CB LYS A 443 20.371 18.874 -26.875 1.00 27.31 C

ANISOU 986 CB LYS A 443 2874 3514 3986 110 -718 6 C

ATOM 987 CG LYS A 443 19.531 19.967 -26.291 1.00 31.52 C

ANISOU 987 CG LYS A 443 3294 4049 4632 188 -724 14 C

ATOM 988 CD LYS A 443 18.276 20.175 -27.156 1.00 38.16 C

ANISOU 988 CD LYS A 443 3995 5022 5481 230 -832 4 C

ATOM 989 CE LYS A 443 17.658 21.570 -26.901 1.00 44.11 C

ANISOU 989 CE LYS A 443 4650 5761 6348 365 -863 48 C ATOM 990 NZ LYS A 443 16.692 21.975 -27.987 1.00 44.43 N ANISOU 990 NZ LYS A 443 4575 5926 6381 450 -1000 80 N ATOM 991 C LYS A 443 22.191 17.276 -26.526 1.00 23.86 C ANISOU 991 C LYS A 443 2652 2965 344.

5. 617 -26 C ATOM 992 O LYS A 443 22.087 16.413 -25.659 1.00 22.54 O ANISOU 992 O LYS A 443 2510 2753 3301 -71 -554 -86 O ATOM 993 N VAL A 444 22.654 17.043 -27.761 1.00 23.85 N ANISOU 993 N VAL A 444 2695 3013 335.

17. 669 -5 N ATOM 994 CA VAL A 444 23.079 15.707 -28.183 1.00 23.44 C ANISOU 994 CA VAL A 444 2724 2958 3226 -53 -656 -74 C ATOM 995 CB VAL A 444 23.278 15.593 -29.728 1.00 24.08 C ANISOU 995 CB VAL A 444 2823 3139 3186 -33 -728 -69 C ATOM 996 CG1 VAL A 444 23.640 14.169 -30.129 1.00 23.87 C ANISOU 996 CG1 VAL A 444 2877 3100 3093 -104 -710 -171 C ATOM 997 CG2 VAL A 444 22.026 16.031 -30.447 1.00 24.33 C ANISOU 997 CG2 VAL A 444 2743 3297 3206 -828 -70 C ATOM 998 C VAL A 444 24.327 15.306 -27.408 1.00 22.67 C ANISOU 998 C VAL A 444 2733 2748 3133 -54 -574 -66 C ATOM 999 O VAL A 444 24.445 14.151 -26.968 1.00 24.02 O ANISOU 999 O VAL A 444 2963 2860 3303 -117 -534 -131 O ATOM 1000 N LEU A 445 25.228 16.270 -27.203 1.00 20.80 N ANISOU 1000 N LEU A 445 2516 2477 291.

16. 553 14 N ATOM 1001 CA LEU A 445 26.470 16.029 -26.491 1.00 19.22 C ANISOU 1001 CA LEU A 445 2395 2194 271.

28. 491 22 C ATOM 1002 CB LEU A 445 27.355 17.284 -26.540 1.00 18.43 C ANISOU 1002 CB LEU A 445 2290 2081 263.

92. 482 107 C ATOM 1003 CG LEU A 445 28.698 17.335 -25.788 1.00 16.91 C ANISOU 1003 CG LEU A 445 2147 1823 2456 111 -430 119 C ATOM 1004 CD1 LEU A 445 29.714 16.292 -26.272 1.00 15.64 C ANISOU 1004 CD1 LEU A 445 2050 1668 2225 114 -410 86 C ATOM 1005 CD2 LEU A 445 29.301 18.716 -25.861 1.00 17.13 C ANISOU 1005 CD2 LEU A 445 2149 1839 2522 148 -425 195 C ATOM 1006 C LEU A 445 26.221 15.634 -25.038 1.00 19.21 C ANISOU 1006 C LEU A 445 2405 2118 2774 -439 -11 C ATOM 1007 O LEU A 445 26.803 14.665 -24.554 1.00 20.41 O ANISOU 1007 O LEU A 445 2635 2211 2909 -32 -404 -39 O ATOM 1008 N PHE A 446 25.386 16.416 -24.350 1.00 18.58 N ANISOU 1008 N PHE A 446 2252 2045 2761 -8 -434 -3 N ATOM 1009 CA PHE A 446 25.072 16.215 -22.948 1.00 17.93 C ANISOU 1009 CA PHE A 446 2174 1919 2722 -43 -376 -31 C ATOM 1010 CB PHE A 446 24.302 17.424 -22.372 1.00 18.01 C ANISOU 1010 CB PHE A 446 2089 1949 2806 -370 -27 C ATOM 1011 CG PHE A 446 25.186 18.610 -21.966 1.00 17.40 C ANISOU 1011 CG PHE A 446 2025 1826 2762.

59. 363 15 C ATOM 1012 CD1 PHE A 446 26.531 18.664 -22.307 1.00 16.25 C ANISOU 1012 CD1 PHE A 446 1946 1647 258.

85. 369 55 C ATOM 1013 CE1 PHE A 446 27.333 19.740 -21.958 1.00 16.45 C ANISOU 1013 CE1 PHE A 446 1974 1630 2646 127 -361 84 C ATOM 1014 CZ PHE A 446 26.800 20.806 -21.285 1.00 17.43 C ANISOU 1014 CZ PHE A 446 2046 1728 2849 153 -350 69 C ATOM 1015 CE2 PHE A 446 25.447 20.791 -20.941 1.00 21.09 C ANISOU 1015 CE2 PHE A 446 2441 2224 3346 147 -342 25 C ATOM 1016 CD2 PHE A 446 24.639 19.701 -21.302 1.00 18.75 C ANISOU 1016 CD2 PHE A 446 2128 1987 300.

97. 348 2 C ATOM 1017 C PHE A 446 24.270 14.927 -22.727 1.00 18.39 C ANISOU 1017 C PHE A 446 2246 1974 2768 -139 -353 -89 C ATOM 1018 O PHE A 446 24.607 14.160 -21.843 1.00 18.65 O ANISOU 1018 O PHE A 446 2357 1942 2788 -177 -302 -95 O ATOM 1019 N GLN A 447 23.240 14.694 -23.545 1.00 18.81 N ANISOU 1019 N GLN A 447 2227 2095 2824 -180 -394 -128 N ATOM 1020 CA GLN A 447 22.379 13.508 -23.457 1.00 19.67 C ANISOU 1020 CA GLN A 447 2333 2203 2937 -294 -374 -195 C ATOM 1021 CB GLN A 447 21.108 13.676 -24.326 1.00 19.41 C ANISOU 1021 CB GLN A 447 2168 2284 2922 -326 -437 -243 C ATOM 1022 CG GLN A 447 20.183 14.825 -23.916 1.00 20.98 C ANISOU 1022 CG GLN A 447 2223 2556 3190 -282 -442 -234 C ATOM 1023 CD GLN A 447 19.493 14.638 -22.559 1.00 23.91 C ANISOU 1023 CD GLN A 447 2554 2915 3616 -353 -348 -267 C ATOM 1024 OE1 GLN A 447 19.925 13.841 -21.725 1.00 20.75 O ANISOU 1024 OE1 GLN A 447 2258 2433 3195 -418 -273 -264 O ATOM 1025 NE2 GLN A 447 18.419 15.397 -22.335 1.00 26.39 N ANISOU 1025 NE2 GLN A 447 2715 3316 3997 -331 -350 -295 N ATOM 1026 C GLN A 447 23.084 12.169 -23.771 1.00 20.15 C ANISOU 1026 C GLN A 447 2524 2184 2950 -339 -364 -221 C ATOM 1027 O GLN A 447 22.659 11.125 -23.307 1.00 21.51 O ANISOU 1027 O GLN A 447 2739 2297 3136 -437 -322 -259 O ATOM 1028 N ASN A 448 24.170 12.210 -24.531 1.00 20.43 N ANISOU 1028 N ASN A 448 2621 2207 2934 -265 -396 -202 N ATOM 1029 CA ASN A 448 24.872 11.006 -24.958 1.00 22.00 C ANISOU 1029 CA ASN A 448 2933 2333 3092 -282 -391 -242 C ATOM 1030 CB ASN A 448 25.032 10.974 -26.496 1.00 22.08 C ANISOU 1030 CB ASN A 448 2930 2422 3036 -256 -453 -284 C ATOM 1031 CG ASN A 448 23.720 10.673 -27.209 1.00 23.31 C ANISOU 1031 CG ASN A 448 3009 2660 3190 -343 -504 -359 C ATOM 1032 OD1 ASN A 448 23.280 9.533 -27.269 1.00 24.47 O ANISOU 1032 OD1 ASN A 448 3195 2755 3349 -439 -495 -443 O ATOM 1033 ND2 ASN A 448 23.088 11.703 -27.735 1.00 23.68 N ANISOU 1033 ND2 ASN A 448 2941 2828 3226 -310 -563 -330 N ATOM 1034 C ASN A 448 26.213 10.800 -24.295 1.00 21.90 C ANISOU 1034 C ASN A 448 3021 2230 3070 -213 -353 -198 C ATOM 1035 O ASN A 448 26.856 9.772 -24.513 1.00 23.82 O ANISOU 1035 O ASN A 448 3361 2395 3293 -206 -344 -230 O ATOM 1036 N TRP A 449 26.606 11.740 -23.448 1.00 22.09 N ANISOU 1036 N TRP A 449 3019 2260 3112 -160 -334 -133 N ATOM 1037 CA TRP A 449 27.908 11.699 -22.745 1.00 22.12 C ANISOU 1037 CA TRP A 449 3095 2205 3105 -89 -313 -92 C ATOM 1038 CB TRP A 449 28.184 13.060 -22.066 1.00 21.28 C ANISOU 1038 CB TRP A 449 2925 2138 3020 -41 -308 -42 C ATOM 1039 CG TRP A 449 29.534 13.158 -21.367 1.00 21.14 C ANISOU 1039 CG TRP A 449 2955 2087 2990.

28. 301 -10 C ATOM 1040 CD1 TRP A 449 29.786 12.971 -20.040 1.00 20.23 C ANISOU 1040 CD1 TRP A 449 2886 1931 286.

31. 278 10 C ATOM 1041 NE1 TRP A 449 31.129 13.124 -19.779 1.00 19.99 N ANISOU 1041 NE1 TRP A 449 2874 1899 2823 107 -295 28 N ATOM 1042 CE2 TRP A 449 31.780 13.406 -20.950 1.00 20.43 C ANISOU 1042 CE2 TRP A 449 2892 1990 2881 146 -314 19 C ATOM 1043 CD2 TRP A 449 30.800 13.453 -21.976 1.00 19.62 C ANISOU 1043 CD2 TRP A 449 2757 1916 278.

100. 319 1 C ATOM 1044 CE3 TRP A 449 31.205 13.729 -23.288 1.00 18.99 C ANISOU 1044 CE3 TRP A 449 2646 1890 2681 125 -335 -3 C ATOM 1045 CZ3 TRP A 449 32.565 13.992 -23.531 1.00 20.81 C ANISOU 1045 CZ3 TRP A 449 2865 2143 2899 187 -331 10 C ATOM 1046 CH2 TRP A 449 33.515 13.972 -22.478 1.00 18.26 C ANISOU 1046 CH2 TRP A 449 2554 1793 2591 230 -327 19 C ATOM 1047 CZ2 TRP A 449 33.141 13.677 -21.188 1.00 18.76 C ANISOU 1047 CZ2 TRP A 449 2659 1805 2663 215 -327 25 C ATOM 1048 C TRP A 449 28.112 10.540 -21.757 1.00 22.76 C ANISOU 1048 C TRP A 449 3285 2175 3186 -114 -275 -87 C ATOM 1049 O TRP A 449 29.253 10.071 -21.571 1.00 24.65 O ANISOU 1049 O TRP A 449 3599 2358 3407 -44 -278 -71 O ATOM 1050 N GLY A 450 27.057 10.056 -21.115 1.00 22.54 N ANISOU 1050 N GLY A 450 3270 2117 3179 -211 -240 -94 N ATOM 1051 CA GLY A 450 27.269 9.021 -20.083 1.00 21.83 C ANISOU 1051 CA GLY A 450 3301 1913 3081 -237 -199 -61 C ATOM 1052 C GLY A 450 26.923 9.581 -18.715 1.00 21.43 C ANISOU 1052 C GLY A 450 3233 1890 3018 -259 -155 -11 C ATOM 1053 O GLY A 450 27.192 10.758 -18.436 1.00 20.21 O

ANISOU 1053 O GLY A 450 3005 1815 2860 -202 -167 1 O

ATOM 1054 N ILE A 451 26.284 8.751 -17.889 1.00 21.10 N

ANISOU 1054 N ILE A 451 3262 1784 2970 -352 -98 14 N

ATOM 1055 CA ILE A 451 25.818 9.147 -16.578 1.00 20.69 C

ANISOU 1055 CA ILE A 451 3202 1772 2887 -392 -39 54 C

ATOM 1056 CB ILE A 451 24.237 9.164 -16.503 1.00 21.84 C

ANISOU 1056 CB ILE A 451 3255 1973 3069 -531 24 13 C

ATOM 1057 CG1 ILE A 451 23.720 10.086 -15.389 1.00 20.59 C

ANISOU 1057 CG1 ILE A 451 3025 1914 2885 -542 83 19 C

ATOM 1058 CD1 ILE A 451 23.706 11.556 -15.790 1.00 19.64 C

ANISOU 1058 CD1 ILE A 451 2765 1897 2800 -456 40 -28 C

ATOM 1059 CG2 ILE A 451 23.649 7.766 -16.361 1.00 22.44 C

ANISOU 1059 CG2 ILE A 451 3427 1942 3156 -663 78 26 C

ATOM 1060 C ILE A 451 26.458 8.155 -15.621 1.00 22.07 C

ANISOU 1060 C ILE A 451 3539 1838 3008 -382 -18 134 C

ATOM 1061 O ILE A 451 26.781 7.044 -16.013 1.00 22.36 O

ANISOU 1061 O ILE A 451 3682 1753 3060 -385 -30 146 O

ATOM 1062 N GLU A 452 26.683 8.553 -14.378 1.00 22.05 N

ANISOU 1062 N GLU A 452 3565 1877 2938 -359 8 187 N

ATOM 1063 CA GLU A 452 27.397 7.691 -13.451 1.00 23.30 C

ANISOU 1063 CA GLU A 452 3882 1946 3025 -326 10 280 C

ATOM 1064 CB GLU A 452 28.909 8.005 -13.455 1.00 22.10 C

ANISOU 1064 CB GLU A 452 3748 1802 2846 -164 -79 296 C

ATOM 1065 CG GLU A 452 29.322 9.401 -12.931 1.00 21.20 C

ANISOU 1065 CG GLU A 452 3532 1826 2696 -103 -103 268 C

ATOM 1066 CD GLU A 452 30.841 9.593 -12.871 1.00 22.68 C

ANISOU 1066 CD GLU A 452 3732 2026 286.

37. 190 281 C

ATOM 1067 OE1 GLU A 452 31.592 8.596 -12.982 1.00 27.30 O

ANISOU 1067 OE1 GLU A 452 4414 2519 3440 105 -229 328 O

ATOM 1068 OE2 GLU A 452 31.303 10.728 -12.689 1.00 23.21 O

ANISOU 1068 OE2 GLU A 452 3706 2189 292.

81. 220 240 O

ATOM 1069 C GLU A 452 26.827 7.884 -12.057 1.00 24.23 C

ANISOU 1069 C GLU A 452 4026 2124 3057 -392 85 331 C

ATOM 1070 O GLU A 452 26.298 8.943 -11.755 1.00 22.41 O

ANISOU 1070 O GLU A 452 3678 2018 2819 -412 115 279 O

ATOM 1071 N HIS A 453 26.937 6.859 -11.220 1.00 26.35 N

ANISOU 1071 N HIS A 453 4453 2300 3257 -423 117 434 N

ATOM 1072 CA HIS A 453 26.636 7.037 -9.814 1.00 29.05 C

ANISOU 1072 CA HIS A 453 4843 2716 3480 -466 183 497 C

ATOM 1073 CB HIS A 453 26.420 5.688 -9.121 1.00 31.54 C

ANISOU 1073 CB HIS A 453 5346 2900 3737 -546 242 627 C

ATOM 1074 CG HIS A 453 25.586 5.793 -7.881 1.00 37.83 C

ANISOU 1074 CG HIS A 453 6167 3786 4420 -660 356 679 C

ATOM 1075 ND1 HIS A 453 26.069 5.479 -6.623 1.00 42.46 N

ANISOU 1075 ND1 HIS A 453 6901 4383 4849 -627 364 804 N

ATOM 1076 CE1 HIS A 453 25.122 5.697 -5.727 1.00 45.28 C

ANISOU 1076 CE1 HIS A 453 7243 4847 5115 -752 487 817 C

ATOM 1077 NE2 HIS A 453 24.054 6.168 -6.351 1.00 44.67 N

ANISOU 1077 NE2 HIS A 453 6999 4830 5145 -855 557 700 N

ATOM 1078 CD2 HIS A 453 24.320 6.241 -7.697 1.00 40.72 C

ANISOU 1078 CD2 HIS A 453 6418 4258 4796 -798 469 618 C

ATOM 1079 C HIS A 453 27.767 7.838 -9.144 1.00 28.67 C

ANISOU 1079 C HIS A 453 4790 2760 3345 -324 106 504 C

ATOM 1080 O HIS A 453 28.940 7.782 -9.559 1.00 28.14 O

ANISOU 1080 O HIS A 453 4741 2654 3297 -194 5 509 O

ATOM 1081 N ILE A 454 27.423 8.618 -8.132 1.00 29.08 N

ANISOU 1081 N ILE A 454 4802 2945 3304 -350 154 488 N

ATOM 1082 CA ILE A 454 28.448 9.403 -7.440 1.00 28.83 C

ANISOU 1082 CA ILE A 454 4760 3009 3183 -232 78 475 C

ATOM 1083 CB ILE A 454 28.400 10.945 -7.822 1.00 27.51 C

ANISOU 1083 CB ILE A 454 4412 2956 3086 -201 60 334 C

ATOM 1084 CG1 ILE A 454 27.220 11.666 -7.174 1.00 27.31 C

ANISOU 1084 CG1 ILE A 454 4309 3040 3029 -292 168 268 C

ATOM 1085 CD1 ILE A 454 27.215 13.162 -7.375 1.00 25.56 C

ANISOU 1085 CD1 ILE A 454 3937 2905 2872 -246 148 138 C ATOM 1086 CG2 ILE A 454 28.360 11.131 -9.313 1.00 26.45 C ANISOU 1086 CG2 ILE A 454 4180 2762 3106 -186 25 277 C ATOM 1087 C ILE A 454 28.381 9.208 -5.937 1.00 30.68 C ANISOU 1087 C ILE A 454 5104 3314 3238 -258 123 553 C ATOM 1088 O ILE A 454 27.341 8.876 -5.395 1.00 32.05 O ANISOU 1088 O ILE A 454 5312 3505 3359 -381 239 587 O ATOM 1089 N ASP A 455 29.506 9.410 -5.269 1.00 32.23 N ANISOU 1089 N ASP A 455 5348 3565 3333 -144 29 580 N ATOM 1090 CA ASP A 455 29.570 9.458 -3.811 1.00 34.84 C ANISOU 1090 CA ASP A 455 5769 4006 3465 -149 49 635 C ATOM 1091 CB ASP A 455 30.984 9.101 -3.357 1.00 36.54 C ANISOU 1091 CB ASP A 455 6075 4220 3587 -3 -92 712 C ATOM 1092 CG ASP A 455 31.449 7.732 -3.876 1.00 40.61 C ANISOU 1092 CG ASP A 455 6722 4552 415.

51. 140 845 C ATOM 1093 OD1 ASP A 455 30.664 6.746 -3.860 1.00 45.61 O ANISOU 1093 OD1 ASP A 455 7471 5067 4792 -46 -50 945 O ATOM 1094 OD2 ASP A 455 32.617 7.641 -4.302 1.00 44.13 O ANISOU 1094 OD2 ASP A 455 7150 4967 4651 190 -265 841 O ATOM 1095 C ASP A 455 29.193 10.845 -3.264 1.00 34.43 C ANISOU 1095 C ASP A 455 5588 4124 3368 -173 89 493 C ATOM 1096 O ASP A 455 29.396 11.863 -3.913 1.00 33.12 O ANISOU 1096 O ASP A 455 5280 3987 3318 -134 49 366 O ATOM 1097 N ASN A 456 28.616 10.872 -2.073 1.00 36.47 N ANISOU 1097 N ASN A 456 5907 4491 3459 -241 178 516 N ATOM 1098 CA ASN A 456 28.410 12.114 -1.357 1.00 36.78 C ANISOU 1098 CA ASN A 456 5852 4697 3426 -245 209 376 C ATOM 1099 CB ASN A 456 27.498 11.878 -0.155 1.00 38.76 C ANISOU 1099 CB ASN A 456 6179 5058 3489 -349 349 415 C ATOM 1100 CG ASN A 456 26.107 11.425 -0.555 1.00 39.81 C ANISOU 1100 CG ASN A 456 6277 5142 3709 -491 505 433 C ATOM 1101 OD1 ASN A 456 25.486 11.995 -1.468 1.00 37.31 O ANISOU 1101 OD1 ASN A 456 5803 4798 3573 -513 535 321 O ATOM 1102 ND2 ASN A 456 25.598 10.397 0.136 1.00 39.68 N ANISOU 1102 ND2 ASN A 456 6402 5117 3558 -591 604 578 N ATOM 1103 C ASN A 456 29.751 12.683 -0.903 1.00 36.67 C ANISOU 1103 C ASN A 456 5840 4760 3333 -121 63 333 C ATOM 1104 O ASN A 456 30.413 12.110 -0.036 1.00 37.97 O ANISOU 1104 O ASN A 456 6134 4970 3323 -74 2 435 O ATOM 1105 N VAL A 457 30.161 13.779 -1.535 1.00 35.06 N ANISOU 1105 N VAL A 457 5490 4565 3266 -71 2 190 N ATOM 1106 CA VAL A 457 31.320 14.556 -1.101 1.00 34.96 C ANISOU 1106 CA VAL A 457 5441 4642 320.

18. 121 106 C ATOM 1107 CB VAL A 457 32.418 14.572 -2.196 1.00 33.72 C ANISOU 1107 CB VAL A 457 5219 4392 3202 106 -247 107 C ATOM 1108 CG1 VAL A 457 33.621 15.370 -1.740 1.00 33.63 C ANISOU 1108 CG1 VAL A 457 5151 4481 3146 179 -372 14 C ATOM 1109 CG2 VAL A 457 32.816 13.127 -2.554 1.00 35.71 C ANISOU 1109 CG2 VAL A 457 5589 4533 3446 151 -290 281 C ATOM 1110 C VAL A 457 30.848 15.978 -0.779 1.00 34.15 C ANISOU 1110 C VAL A 457 5219 4633 3121 -16 -68 -85 C ATOM 1111 O VAL A 457 30.251 16.622 -1.639 1.00 32.78 O ANISOU 1111 O VAL A 457 4932 4395 3126 -42 -17 -167 O ATOM 1112 N MSE A 458 31.088 16.452 0.451 1.00 35.25 N ANISOU 1112 N MSE A 458 5390 4923 3079 -11 -81 -157 N ATOM 1113 CA MSE A 458 30.699 17.815 0.846 1.00 34.91 C ANISOU 1113 CA MSE A 458 5246 4964 3055 -34 -32 -361 C ATOM 1114 CB MSE A 458 30.871 18.047 2.353 1.00 37.58 C ANISOU 1114 CB MSE A 458 5655 5487 3136 -39 -33 -424 C ATOM 1115 CG MSE A 458 30.252 19.378 2.825 1.00 36.62 C ANISOU 1115 CG MSE A 458 5440 5445 3030 -71.

49. 651 C ATOM 1116 SE MSE A 458 30.457 19.706 4.676 0.90 40.81 SE ANISOU 1116 SE MSE A 458 6058 6227 3221 -80.

51. 762 SE ATOM 1117 CE MSE A 458 29.473 21.279 4.926 1.00 43.27 C ANISOU 1117 CE MSE A 458 6238 6576 3626 -113 185 -1053 C ATOM 1118 C MSE A 458 31.466 18.877 0.071 1.00 33.44 C ANISOU 1118 C MSE A 458 4933 4714 305.

13. 127 -485 C ATOM 1119 O MSE A 458 32.657 18.724 -0.155 1.00 34.08 O ANISOU 1119 O MSE A 458 5016 4783 3152.

71. 259 -451 O ATOM 1120 N GLY A 459 30.783 19.943 -0.342 1.00 32.49 N ANISOU 1120 N GLY A 459 4703 4553 3090 -12 -57 -623 N ATOM 1121 CA GLY A 459 31.402 21.007 -1.139 1.00 31.36 C ANISOU 1121 CA GLY A 459 4449 4324 314.

18. 129 -728 C ATOM 1122 C GLY A 459 31.266 20.849 -2.641 1.00 30.19 C ANISOU 1122 C GLY A 459 4243 4025 320.

28. 132 -646 C ATOM 1123 O GLY A 459 31.810 21.635 -3.395 1.00 28.91 O ANISOU 1123 O GLY A 459 4001 3786 319.

47. 186 -701 O ATOM 1124 N MSE A 460 30.504 19.844 -3.079 1.00 30.67 N ANISOU 1124 N MSE A 460 4344 4046 326.

4. 68 -519 N ATOM 1125 CA MSE A 460 30.479 19.418 -4.475 1.00 30.71 C ANISOU 1125 CA MSE A 460 4316 3927 342.

14. 86 -427 C ATOM 1126 CB MSE A 460 31.612 18.422 -4.661 1.00 30.18 C ANISOU 1126 CB MSE A 460 4321 3842 330.

58. 185 -308 C ATOM 1127 CG MSE A 460 32.091 18.176 -6.021 1.00 31.46 C ANISOU 1127 CG MSE A 460 4442 3899 3611.

88. 234 -249 C ATOM 1128 SE MSE A 460 33.476 16.771 -5.852 0.90 37.35 SE ANISOU 1128 SE MSE A 460 5293 4649 4248 165 -348 -114 SE ATOM 1129 CE MSE A 460 34.825 17.837 -4.917 1.00 35.43 C ANISOU 1129 CE MSE A 460 4991 4531 3939 209 -461 -235 C ATOM 1130 C MSE A 460 29.152 18.715 -4.753 1.00 28.46 C ANISOU 1130 C MSE A 460 4042 3618 3154 -41.

24. 362 C ATOM 1131 O MSE A 460 28.575 18.079 -3.850 1.00 28.50 O ANISOU 1131 O MSE A 460 4120 3694 3015 -88.

97. 325 O ATOM 1132 N VAL A 461 28.671 18.840 -5.989 1.00 25.91 N ANISOU 1132 N VAL A 461 3643 3204 2995 -44.

34. 348 N ATOM 1133 CA VAL A 461 27.446 18.159 -6.436 1.00 25.77 C ANISOU 1133 CA VAL A 461 3614 3165 3014 -103 121 -296 C ATOM 1134 CB VAL A 461 26.129 19.057 -6.389 1.00 26.21 C ANISOU 1134 CB VAL A 461 3552 3258 3149 -125 217 -406 C ATOM 1135 CG1 VAL A 461 25.667 19.320 -4.974 1.00 28.85 C ANISOU 1135 CG1 VAL A 461 3904 3710 3347 -154 306 -485 C ATOM 1136 CG2 VAL A 461 26.293 20.405 -7.139 1.00 25.60 C ANISOU 1136 CG2 VAL A 461 3368 3122 3236 -60 167 -496 C ATOM 1137 C VAL A 461 27.621 17.605 -7.849 1.00 24.27 C ANISOU 1137 C VAL A 461 3411 2873 2939 -92.

69. 216 C ATOM 1138 O VAL A 461 28.436 18.099 -8.633 1.00 22.83 O ANISOU 1138 O VAL A 461 3191 2640 2843 -37 -224 O ATOM 1139 N GLY A 462 26.837 16.583 -8.174 1.00 23.87 N ANISOU 1139 N GLY A 462 3388 2795 2886 -154 122 -147 N ATOM 1140 CA GLY A 462 26.661 16.169 -9.564 1.00 21.99 C ANISOU 1140 CA GLY A 462 3116 2478 2763 -158.

90. 107 C ATOM 1141 C GLY A 462 25.731 17.096 -10.366 1.00 21.21 C ANISOU 1141 C GLY A 462 2876 2387 2797 -156 109 -179 C ATOM 1142 O GLY A 462 25.023 17.917 -9.803 1.00 21.23 O ANISOU 1142 O GLY A 462 2805 2448 2813 -158 166 -260 O ATOM 1143 N VAL A 463 25.746 16.937 -11.686 1.00 19.62 N ANISOU 1143 N VAL A 463 2639 2130 2686 -142.

58. 151 N ATOM 1144 CA VAL A 463 24.947 17.731 -12.581 1.00 19.75 C ANISOU 1144 CA VAL A 463 2533 2153 2820 -125.

52. 195 C ATOM 1145 CB VAL A 463 25.767 18.971 -13.157 1.00 19.50 C ANISOU 1145 CB VAL A 463 2461 2085 2865 -37 -19 -215 C ATOM 1146 CG1 VAL A 463 26.906 18.526 -14.079 1.00 18.45 C ANISOU 1146 CG1 VAL A 463 2382 1899 2729 -11 -93 -148 C ATOM 1147 CG2 VAL A 463 24.903 19.884 -13.892 1.00 20.87 C ANISOU 1147 CG2 VAL A 463 2520 2259 3151 -5 -26 -248 C ATOM 1148 C VAL A 463 24.402 16.803 -13.675 1.00 19.21 C ANISOU 1148 C VAL A 463 2454 2061 2785 -173.

38. 153 C ATOM 1149 O VAL A 463 25.117 15.975 -14.245 1.00 17.34 O ANISOU 1149 O VAL A 463 2295 1770 2523 -173 -6 -98 O ATOM 1150 N LEU A 464 23.113 16.938 -13.952 1.00 20.10 N ANISOU 1150 N LEU A 464 2460 2221 2955 -211.

75. 193 N ATOM 1151 CA LEU A 464 22.451 16.147 -14.993 1.00 20.06 C ANISOU 1151 CA LEU A 464 2423 2214 2986 -267.

55. 179 C ATOM 1152 CB LEU A 464 20.978 15.896 -14.611 1.00 20.50 C ANISOU 1152 CB LEU A 464 2379 2345 3065 -356 136 -228 C ATOM 1153 CG LEU A 464 20.640 15.224 -13.271 1.00 20.46 C ANISOU 1153 CG LEU A 464 2432 2366 2978 -451 249 -224 C ATOM 1154 CD1 LEU A 464 19.137 15.006 -13.119 1.00 21.72 C ANISOU 1154 CD1 LEU A 464 2461 2614 3178 -551 334 -280 C ATOM 1155 CD2 LEU A 464 21.359 13.932 -13.071 1.00 18.35 C ANISOU 1155 CD2 LEU A 464 2330 2012 2629 -510 252 -143 C ATOM 1156 C LEU A 464 22.547 16.908 -16.326 1.00 19.95 C ANISOU 1156 C LEU A 464 2335 2196 3048 -190 -34 -178 C ATOM 1157 O LEU A 464 22.865 18.083 -16.323 1.00 19.98 O ANISOU 1157 O LEU A 464 2302 2195 3096 -107 -60 -189 O ATOM 1158 N PRO A 465 22.308 16.229 -17.470 1.00 20.59 N ANISOU 1158 N PRO A 465 2409 2275 3140 -222 -82 -163 N ATOM 1159 CA PRO A 465 22.309 16.897 -18.783 1.00 21.07 C ANISOU 1159 CA PRO A 465 2405 2352 3247 -154 -167 -151 C ATOM 1160 CB PRO A 465 21.839 15.803 -19.740 1.00 21.49 C ANISOU 1160 CB PRO A 465 2459 2425 3283 -226 -198 -161 C ATOM 1161 CG PRO A 465 22.268 14.552 -19.122 1.00 20.52 C ANISOU 1161 CG PRO A 465 2456 2236 3104 -304 -147 -152 C ATOM 1162 CD PRO A 465 22.139 14.772 -17.616 1.00 21.10 C ANISOU 1162 CD PRO A 465 2542 2310 3163 -323 -62 -154 C ATOM 1163 C PRO A 465 21.445 18.147 -18.919 1.00 22.58 C ANISOU 1163 C PRO A 465 2460 2598 3522 -89 -184 -180 C ATOM 1164 O PRO A 465 21.848 19.088 -19.645 1.00 22.93 O ANISOU 1164 O PRO A 465 2489 2623 3600 -1 -247 -143 O ATOM 1165 N ASP A 466 20.288 18.182 -18.246 1.00 23.41 N ANISOU 1165 N ASP A 466 2467 2765 3663 -127 -125 -240 N ATOM 1166 CA ASP A 466 19.484 19.423 -18.181 1.00 24.48 C ANISOU 1166 CA ASP A 466 2467 2944 3890 -41 -132 -280 C ATOM 1167 CB ASP A 466 17.987 19.137 -17.935 1.00 25.77 C ANISOU 1167 CB ASP A 466 2481 3214 4096 -97 -86 -353 C ATOM 1168 CG ASP A 466 17.711 18.432 -16.596 1.00 27.78 C ANISOU 1168 CG ASP A 466 2762 3494 4300 -205.

43. 396 C ATOM 1169 OD1 ASP A 466 18.616 18.350 -15.739 1.00 29.82 O ANISOU 1169 OD1 ASP A 466 3148 3692 4490 -212.

88. 374 O ATOM 1170 OD2 ASP A 466 16.564 17.962 -16.383 1.00 29.01 O ANISOU 1170 OD2 ASP A 466 2805 3739 4477 -288.

100. 451 O ATOM 1171 C ASP A 466 20.026 20.476 -17.185 1.00 24.43 C ANISOU 1171 C ASP A 466 2490 2886 3906.

30. 90 -302 C ATOM 1172 O ASP A 466 19.377 21.498 -16.948 1.00 24.93 O ANISOU 1172 O ASP A 466 2453 2967 4054 106 -80 -352 O ATOM 1173 N MSE A 467 21.206 20.210 -16.610 1.00 24.00 N ANISOU 1173 N MSE A 467 2568 2770 378.

9. 70 -275 N ATOM 1174 CA MSE A 467 21.905 21.152 -15.710 1.00 24.32 C ANISOU 1174 CA MSE A 467 2648 2764 382.

63. 45 -305 C ATOM 1175 CB MSE A 467 22.058 22.557 -16.331 1.00 24.10 C ANISOU 1175 CB MSE A 467 2574 2675 3907 171 -105 -297 C ATOM 1176 CG MSE A 467 23.071 22.602 -17.472 1.00 23.28 C ANISOU 1176 CG MSE A 467 2537 2512 3797 191 -185 -203 C ATOM 1177 SE MSE A 467 24.823 21.862 -16.977 0.90 26.00 SE ANISOU 1177 SE MSE A 467 3030 2817 4031 137 -179 -170 SE ATOM 1178 CE MSE A 467 25.294 23.125 -15.564 1.00 22.62 C ANISOU 1178 CE MSE A 467 2609 2344 3643 172 -138 -259 C ATOM 1179 C MSE A 467 21.320 21.226 -14.313 1.00 25.38 C ANISOU 1179 C MSE A 467 2754 2951 3936 3.

55. 390 C ATOM 1180 O MSE A 467 21.736 22.059 -13.507 1.00 26.95 O ANISOU 1180 O MSE A 467 2972 3126 4141 7.

79. 444 O ATOM 1181 N THR A 468 20.388 20.320 -14.021 1.00 25.59 N ANISOU 1181 N THR A 468 2740 3056 3927 -51 119 -408 N ATOM 1182 CA THR A 468 19.830 20.146 -12.684 1.00 25.97 C ANISOU 1182 CA THR A 468 2773 3176 3917 -106 235 -475 C ATOM 1183 CB THR A 468 18.559 19.255 -12.705 1.00 27.06 C ANISOU 1183 CB THR A 468 2822 3405 4054 -209 304 -491 C ATOM 1184 OG1 THR A 468 17.500 19.937 -13.395 1.00 30.40 O ANISOU 1184 OG1 THR A 468 3070 3880 4602 -149 278 -546 O ATOM 1185 CG2 THR A 468 18.066 18.937 -11.284 1.00 30.00 C ANISOU 1185 CG2 THR A 468 3200 3861 4340 -288 444 -541 C ATOM 1186 C THR A 468 20.882 19.520 -11.783 1.00 24.91 C ANISOU 1186 C THR A 468 2799 3016 3650 -153 260 -435 C ATOM 1187 O THR A 468 21.500 18.510 -12.160 1.00 23.50 O ANISOU 1187 O THR A 468 2721 2793 3415 -201 223 -351 O ATOM 1188 N PRO A 469 21.109 20.120 -10.592 1.00 25.19 N ANISOU 1188 N PRO A 469 2858 3082 3631 -131 315 -501 N ATOM 1189 CA PRO A 469 22.089 19.534 -9.669 1.00 24.77 C ANISOU 1189 CA PRO A 469 2952 3026 3434 -167 326 -461 C ATOM 1190 CB PRO A 469 22.210 20.588 -8.551 1.00 24.83 C ANISOU 1190 CB PRO A 469 2946 3078 3409 -120 369 -571 C ATOM 1191 CG PRO A 469 20.960 21.302 -8.583 1.00 26.70 C ANISOU 1191 CG PRO A 469 3035 3365 3743 -94 434 -668 C ATOM 1192 CD PRO A 469 20.505 21.340 -10.031 1.00 25.78 C ANISOU 1192 CD PRO A 469 2830 3197 3768 -64 364 -622 C ATOM 1193 C PRO A 469 21.549 18.221 -9.098 1.00 25.27 C ANISOU 1193 C PRO A 469 3071 3142 3390 -285 412 -407 C ATOM 1194 O PRO A 469 20.345 18.033 -8.949 1.00 25.16 O ANISOU 1194 O PRO A 469 2965 3199 3396 -348 501 -444 O ATOM 1195 N SER A 470 22.455 17.313 -8.793 1.00 24.98 N ANISOU 1195 N SER A 470 3182 3064 3245 -314 385 -316 N ATOM 1196 CA SER A 470 22.073 16.051 -8.215 1.00 25.82 C ANISOU 1196 CA SER A 470 3375 3189 3248 -425 463 -243 C ATOM 1197 CB SER A 470 21.885 14.999 -9.301 1.00 25.56 C ANISOU 1197 CB SER A 470 3359 3073 3278 -482 430 -169 C ATOM 1198 OG SER A 470 21.558 13.741 -8.711 1.00 26.57 O ANISOU 1198 OG SER A 470 3590 3189 3315 -600 509 -90 O ATOM 1199 C SER A 470 23.142 15.585 -7.255 1.00 25.97 C ANISOU 1199 C SER A 470 3556 3199 3112 -413 444 -175 C ATOM 1200 O SER A 470 24.333 15.726 -7.510 1.00 24.16 O ANISOU 1200 O SER A 470 3385 2915 2880 -333 339 -148 O ATOM 1201 N THR A 471 22.695 15.018 -6.149 1.00 27.91 N ANISOU 1201 N THR A 471 3869 3513 3224 -495 547 -143 N ATOM 1202 CA THR A 471 23.597 14.451 -5.161 1.00 29.38 C ANISOU 1202 CA THR A 471 4221 3704 3238 -487 529 -57 C ATOM 1203 CB THR A 471 23.171 14.821 -3.704 1.00 30.73 C ANISOU 1203 CB THR A 471 4408 4020 3246 -523 638 -106 C ATOM 1204 OG1 THR A 471 21.791 14.497 -3.513 1.00 33.75 O ANISOU 1204 OG1 THR A 471 4724 4465 3636 -644 787 -120 O ATOM 1205 CG2 THR A 471 23.366 16.340 -3.446 1.00 32.23 C ANISOU 1205 CG2 THR A 471 4493 4284 3469 -432 612 -268 C ATOM 1206 C THR A 471 23.718 12.925 -5.361 1.00 29.30 C ANISOU 1206 C THR A 471 4350 3591 3193 -555 530 94 C ATOM 1207 O THR A 471 24.416 12.246 -4.615 1.00 30.80 O ANISOU 1207 O THR A 471 4695 3763 3244 -545 509 197 O ATOM 1208 N GLU A 472 23.057 12.397 -6.388 1.00 28.16 N ANISOU 1208 N GLU A 472 4152 3371 3176 -619 544 105 N ATOM 1209 CA GLU A 472 22.982 10.945 -6.598 1.00 28.80 C ANISOU 1209 CA GLU A 472 4360 3336 3246 -706 563 226 C ATOM 1210 CB GLU A 472 21.524 10.456 -6.513 1.00 30.19 C ANISOU 1210 CB GLU A 472 4475 3546 3451 -873 704 218 C ATOM 1211 CG GLU A 472 20.831 10.674 -5.152 1.00 34.77 C ANISOU 1211 CG GLU A 472 5053 4266 3892 -953 848 212 C ATOM 1212 CD GLU A 472 19.477 11.392 -5.276 1.00 40.82 C ANISOU 1212 CD GLU A 472 5606 5160 4744 -1019 952 79 C ATOM 1213 OE1 GLU A 472 18.438 10.760 -5.008 1.00 43.43 O ANISOU 1213 OE1 GLU A 472 5909 5526 5067 -1176 1085 99 O ATOM 1214 OE2 GLU A 472 19.441 12.599 -5.641 1.00 42.85 O ANISOU 1214 OE2 GLU A 472 5717 5482 5083 -914 904 -45 O ATOM 1215 C GLU A 472 23.616 10.535 -7.934 1.00 26.87 C ANISOU 1215 C GLU A 472 4128 2959 3124 -647 448 242 C ATOM 1216 O GLU A 472 24.293 9.534 -8.021 1.00 26.79 O ANISOU 1216 O GLU A 472 4261 2832 3087 -633 404 339 O ATOM 1217 N MSE A 473 23.414 11.334 -8.971 1.00 25.30 N ANISOU 1217 N MSE A 473 3780 2780 3052 -603 399 145 N ATOM 1218 CA MSE A 473 23.895 10.993 -10.300 1.00 23.42 C ANISOU 1218 CA MSE A 473 3540 2442 2915 -559 305 147 C ATOM 1219 CB MSE A 473 22.729 10.564 -11.227 1.00 24.39 C ANISOU 1219 CB MSE A 473 3575 2550 3143 -667 341 105 C ATOM 1220 CG MSE A 473 21.879 9.393 -10.755 1.00 22.32 C ANISOU 1220 CG MSE A 473 3383 2245 2854 -828 445 157 C ATOM 1221 SE MSE A 473 22.758 7.582 -10.747 0.90 27.95 SE ANISOU 1221 SE MSE A 473 4356 2738 3528 -855 419 296 SE ATOM 1222 CE MSE A 473 23.101 7.399 -12.636 1.00 20.44 C ANISOU 1222 CE MSE A 473 3347 1704 2713 -798 301 216 C ATOM 1223 C MSE A 473 24.575 12.199 -10.916 1.00 22.43 C ANISOU 1223 C MSE A 473 3320 2354 2848 -433 214 81 C ATOM 1224 O MSE A 473 24.300 13.376 -10.550 1.00 22.03 O ANISOU 1224 O MSE A 473 3168 2395 2807 -401 232 9 O ATOM 1225 N SER A 474 25.430 11.929 -11.891 1.00 20.89 N ANISOU 1225 N SER A 474 3156 2083 2699 -366 125 99 N ATOM 1226 CA SER A 474 26.072 13.028 -12.627 1.00 19.23 C ANISOU 1226 CA SER A 474 2857 1900 2551 -266 47 49 C ATOM 1227 CB SER A 474 27.291 13.535 -11.840 1.00 18.96 C ANISOU 1227 CB SER A 474 2868 1886 2448 -177 2 61 C ATOM 1228 OG SER A 474 27.784 14.746 -12.377 1.00 16.50 O ANISOU 1228 OG SER A 474 2462 1603 2203 -107 -50 7 O ATOM 1229 C SER A 474 26.509 12.576 -14.024 1.00 18.90 C ANISOU 1229 C SER A 474 2818 1792 2572 -236 -19 56 C ATOM 1230 O SER A 474 26.803 11.396 -14.234 1.00 17.99 O ANISOU 1230 O SER A 474 2805 1592 2438 -253 -27 99 O ATOM 1231 N MSE A 475 26.581 13.518 -14.969 1.00 18.62 N ANISOU 1231 N MSE A 475 2681 1790 2605 -186 -65 13 N ATOM 1232 CA MSE A 475 27.294 13.281 -16.212 1.00 19.11 C ANISOU 1232 CA MSE A 475 2751 1815 2697 -138 -129 20 C ATOM 1233 CB MSE A 475 27.395 14.576 -17.035 1.00 19.24 C ANISOU 1233 CB MSE A 475 2658 1880 2771 -84 -169 -7 C ATOM 1234 CG MSE A 475 26.060 14.982 -17.637 1.00 19.93 C ANISOU 1234 CG MSE A 475 2644 2015 2915 -127 -159 -41 C ATOM 1235 SE MSE A 475 26.115 16.409 -18.957 0.90 21.44 SE ANISOU 1235 SE MSE A 475 2727 2246 3173 -52 -225 -41 SE ATOM 1236 CE MSE A 475 26.632 17.884 -17.856 1.00 18.53 C ANISOU 1236 CE MSE A 475 2330 1873 283.

6. 208 -53 C ATOM 1237 C MSE A 475 28.676 12.781 -15.867 1.00 18.97 C ANISOU 1237 C MSE A 475 2830 1750 2629 -68 -163 61 C ATOM 1238 O MSE A 475 29.338 13.335 -14.995 1.00 18.37 O ANISOU 1238 O MSE A 475 2759 1703 2518 -23 -174 68 O ATOM 1239 N ARG A 476 29.102 11.717 -16.541 1.00 19.82 N ANISOU 1239 N ARG A 476 3007 1787 2736 -55 -185 76 N ATOM 1240 CA ARG A 476 30.380 11.052 -16.273 1.00 20.30 C ANISOU 1240 CA ARG A 476 3158 1796 276.

27. 221 112 C ATOM 1241 CB ARG A 476 30.630 10.005 -17.344 1.00 20.86 C ANISOU 1241 CB ARG A 476 3281 1790 285.

42. 238 98 C ATOM 1242 CG ARG A 476 32.003 9.337 -17.254 1.00 24.78 C ANISOU 1242 CG ARG A 476 3849 2233 3333 153 -279 122 C ATOM 1243 CD ARG A 476 32.373 8.494 -18.498 1.00 24.21 C ANISOU 1243 CD ARG A 476 3807 2100 3292 190 -293 77 C ATOM 1244 NE ARG A 476 31.927 9.009 -19.813 1.00 28.63 N ANISOU 1244 NE ARG A 476 4278 2724 3877 152 -291 14 N ATOM 1245 CZ ARG A 476 32.680 9.734 -20.648 1.00 28.25 C ANISOU 1245 CZ ARG A 476 4147 2758 3829 211 -311 -11 C ATOM 1246 NH1 ARG A 476 33.921 10.119 -20.292 1.00 26.44 N ANISOU 1246 NH1 ARG A 476 3889 2565 3593 303 -333 8 N ATOM 1247 NH2 ARG A 476 32.181 10.089 -21.830 1.00 24.34 N ANISOU 1247 NH2 ARG A 476 3593 2320 3336 173 -310 -52 N ATOM 1248 C ARG A 476 31.621 11.984 -16.096 1.00 19.03 C ANISOU 1248 C ARG A 476 2942 1696 2591 121 -269 108 C ATOM 1249 O ARG A 476 32.010 12.709 -17.012 1.00 16.62 O ANISOU 1249 O ARG A 476 2556 1432 2328 149 -291 79 O ATOM 1250 N GLY A 477 32.221 11.942 -14.899 1.00 18.74 N ANISOU 1250 N GLY A 477 2952 1671 2495 159 -285 140 N ATOM 1251 CA GLY A 477 33.429 12.703 -14.578 1.00 17.97 C ANISOU 1251 CA GLY A 477 2803 1637 2389 236 -337 126 C ATOM 1252 C GLY A 477 33.226 14.205 -14.333 1.00 17.20 C ANISOU 1252 C GLY A 477 2603 1614 2317 207 -329 77 C ATOM 1253 O GLY A 477 34.210 14.931 -14.151 1.00 15.87 O ANISOU 1253 O GLY A 477 2380 1495 2157 250 -370 52 O ATOM 1254 N ILE A 478 31.964 14.675 -14.355 1.00 16.13 N ANISOU 1254 N ILE A 478 2436 1485 2208 135 -277 56 N ATOM 1255 CA ILE A 478 31.645 16.097 -14.197 1.00 15.15 C ANISOU 1255 CA ILE A 478 2221 1406 2129 118 -266 4 C ATOM 1256 CB ILE A 478 30.602 16.635 -15.259 1.00 15.06 C ANISOU 1256 CB ILE A 478 2137 1385 220.

83. 240 -12 C ATOM 1257 CG1 ILE A 478 30.870 16.165 -16.718 1.00 12.67 C ANISOU 1257 CG1 ILE A 478 1829 1058 192.

99. 266 15 C ATOM 1258 CD1 ILE A 478 32.254 16.479 -17.326 1.00 8.92 C ANISOU 1258 CD1 ILE A 478 1332 591 1465 154 -306 24 C ATOM 1259 CG2 ILE A 478 30.433 18.171 -15.129 1.00 15.73 C ANISOU 1259 CG2 ILE A 478 2137 1489 235.

90. 237 -59 C ATOM 1260 C ILE A 478 31.087 16.390 -12.800 1.00 16.26 C ANISOU 1260 C ILE A 478 2381 1587 220.

87. 228 -24 C ATOM 1261 O ILE A 478 30.163 15.703 -12.334 1.00 16.78 O ANISOU 1261 O ILE A 478 2496 1650 223.

35. 175 -4 O ATOM 1262 N ARG A 479 31.657 17.401 -12.128 1.00 16.30 N ANISOU 1262 N ARG A 479 2348 1635 2210 108 -251 -77 N ATOM 1263 CA ARG A 479 31.158 17.854 -10.825 1.00 16.29 C ANISOU 1263 CA ARG A 479 2357 1689 214.

82. 213 -129 C ATOM 1264 CB ARG A 479 32.041 17.347 -9.667 1.00 17.20 C ANISOU 1264 CB ARG A 479 2549 1855 2130 110 -254 -112 C ATOM 1265 CG ARG A 479 32.242 15.837 -9.578 1.00 17.87 C ANISOU 1265 CG ARG A 479 2744 1910 2135 125 -266 -8 C ATOM 1266 CD ARG A 479 30.940 15.106 -9.170 1.00 19.88 C ANISOU 1266 CD ARG A 479 3064 2151 233.

51. 176 33 C ATOM 1267 NE ARG A 479 31.198 13.695 -8.923 1.00 22.90 N ANISOU 1267 NE ARG A 479 3575 2483 264.

61. 187 138 N ATOM 1268 CZ ARG A 479 31.224 12.743 -9.866 1.00 24.84 C ANISOU 1268 CZ ARG A 479 3860 2631 294.

66. 195 193 C ATOM 1269 NH1 ARG A 479 30.991 13.014 -11.161 1.00 21.80 N ANISOU 1269 NH1 ARG A 479 3392 2208 268.

57. 195 153 N ATOM 1270 NH2 ARG A 479 31.452 11.491 -9.507 1.00 27.04 N ANISOU 1270 NH2 ARG A 479 4270 2843 316.

80. 203 287 N ATOM 1271 C ARG A 479 31.081 19.369 -10.792 1.00 16.55 C ANISOU 1271 C ARG A 479 2300 1729 225.

85. 209 -222 C ATOM 1272 O ARG A 479 31.858 20.053 -11.462 1.00 16.48 O ANISOU 1272 O ARG A 479 2240 1691 2330 108 -255 -234 O ATOM 1273 N VAL A 480 30.163 19.894 -9.992 1.00 17.45 N ANISOU 1273 N VAL A 480 2396 1878 235.

59. 149 -289 N ATOM 1274 CA VAL A 480 30.056 21.335 -9.776 1.00 17.94 C ANISOU 1274 CA VAL A 480 2387 1932 249.

69. 142 -394 C ATOM 1275 CB VAL A 480 28.637 21.841 -10.120 1.00 17.22 C ANISOU 1275 CB VAL A 480 2229 1821 249.

62. 74 -429 C ATOM 1276 CG1 VAL A 480 28.491 23.277 -9.739 1.00 18.86 C ANISOU 1276 CG1 VAL A 480 2378 2004 278.

87. 61 -546 C ATOM 1277 CG2 VAL A 480 28.341 21.649 -11.590 1.00 16.12 C

ANISOU 1277 CG2 VAL A 480 2051 1622 245.

72. 96 -352

ATOM 1278 C VAL A 480 30.431 21.686 -8.330 1.00 19.46 C ANISOU 1278 C VAL A 480 2611 2200 258.

64. 140 -483 C ATOM 1279 O VAL A 480 29.897 21.106 -7.379 1.00 20.11 O ANISOU 1279 O VAL A 480 2745 2355 2539.

41. 90 -485 O ATOM 1280 N SER A 481 31.353 22.635 -8.168 1.00 20.47 N ANISOU 1280 N SER A 481 2707 2315 275.

77. 194 -558 N ATOM 1281 CA SER A 481 31.759 23.081 -6.858 1.00 22.30 C ANISOU 1281 CA SER A 481 2960 2626 288.

70. 207 -666 C ATOM 1282 CB SER A 481 33.078 23.835 -6.956 1.00 22.36 C ANISOU 1282 CB SER A 481 2929 2614 295.

72. 292 -723 C ATOM 1283 OG SER A 481 33.419 24.393 -5.699 1.00 24.36 O ANISOU 1283 OG SER A 481 3192 2948 311.

58. 312 -855 O ATOM 1284 C SER A 481 30.670 23.933 -6.189 1.00 24.56 C ANISOU 1284 C SER A 481 3218 2926 318.

60. 123 -791 C ATOM 1285 O SER A 481 30.019 24.767 -6.836 1.00 23.76 O ANISOU 1285 O SER A 481 3052 2737 324.

74. 89 -829 O ATOM 1286 N LYS A 482 30.448 23.692 -4.903 1.00 27.48 N ANISOU 1286 N LYS A 482 3637 3408 339.

45. 89 -850 N ATOM 1287 CA LYS A 482 29.583 24.554 -4.094 1.00 31.02 C ANISOU 1287 CA LYS A 482 4056 3893 3836.

41. 6 -1002 C ATOM 1288 CB LYS A 482 28.838 23.725 -3.047 1.00 32.27 C ANISOU 1288 CB LYS A 482 4275 4186 3798 1.

78. 988 C ATOM 1289 CG LYS A 482 27.735 22.854 -3.618 1.00 32.74 C ANISOU 1289 CG LYS A 482 4325 4232 3881 -11 159 -873 C ATOM 1290 CD LYS A 482 27.113 22.055 -2.499 1.00 40.38 C ANISOU 1290 CD LYS A 482 5361 5334 4646 -60 252 -853 C ATOM 1291 CE LYS A 482 25.586 22.137 -2.501 1.00 43.54 C ANISOU 1291 CE LYS A 482 5686 5766 5094 -88 391 -897 C ATOM 1292 NZ LYS A 482 25.001 21.133 -1.548 1.00 47.71 N ANISOU 1292 NZ LYS A 482 6289 6419 5421 -161 493 -835 N ATOM 1293 C LYS A 482 30.357 25.666 -3.391 1.00 33.07 C ANISOU 1293 C LYS A 482 4304 4164 4099.

42.

55. 1167 C ATOM 1294 O LYS A 482 29.775 26.460 -2.686 1.00 34.72 O ANISOU 1294 O LYS A 482 4492 4396 4304 4.

7. 1320 O ATOM 1295 N MSE A 483 31.670 25.718 -3.556 1.00 34.66 N ANISOU 1295 N MSE A 483 4509 4352 430.

37. 163 -1151 N ATOM 1296 CA MSE A 483 32.448 26.793 -2.918 1.00 37.65 C ANISOU 1296 CA MSE A 483 4866 4739 470.

19. 216 -1322 C ATOM 1297 CB MSE A 483 33.914 26.410 -2.812 1.00 37.80 C ANISOU 1297 CB MSE A 483 4893 4819 465.

7. 340 -1286 C ATOM 1298 CG MSE A 483 34.138 25.073 -2.119 1.00 39.83 C ANISOU 1298 CG MSE A 483 5231 5224 467.

26. 372 -1178 C ATOM 1299 SE MSE A 483 33.330 25.128 -0.344 0.90 47.98 SE ANISOU 1299 SE MSE A 483 6338 6432 546.

13. 299 -1311 SE ATOM 1300 CE MSE A 483 34.165 26.683 0.484 1.00 37.03 C ANISOU 1300 CE MSE A 483 4897 5079 4093 -21 -371 -1592 C ATOM 1301 C MSE A 483 32.325 28.052 -3.738 1.00 38.73 C ANISOU 1301 C MSE A 483 4933 4704 5077.

19. 203 -1393 C ATOM 1302 O MSE A 483 32.588 27.979 -4.960 1.00 38.53 O ANISOU 1302 O MSE A 483 4879 4574 518.

23. 229 -1272 O ATOM 1303 OXT MSE A 483 31.982 29.121 -3.192 1.00 40.68 O ANISOU 1303 OXT MSE A 483 5163 4914 538.

17. 166 -1568 O ATOM 1304 N SER B 320 6.053 17.488 -14.523 1.00 52.35 N ANISOU 1304 N SER B 320 7545 5144 7203 2251 154 -336 N ATOM 1305 CA SER B 320 6.175 16.006 -14.678 1.00 50.09 C ANISOU 1305 CA SER B 320 6969 5155 6909 2037 116 -339 C ATOM 1306 CB SER B 320 5.622 15.284 -13.442 1.00 49.98 C ANISOU 1306 CB SER B 320 6809 5295 6886 2058 243 -458 C ATOM 1307 OG SER B 320 6.227 14.008 -13.284 1.00 47.08 O ANISOU 1307 OG SER B 320 6311 5089 6488 1786 217 -488 O ATOM 1308 C SER B 320 5.493 15.472 -15.958 1.00 50.02 C ANISOU 1308 C SER B 320 6692 5379 6934 209.

11. 208 C ATOM 1309 O SER B 320 4.593 16.118 -16.530 1.00 52.10 O ANISOU 1309 O SER B 320 6909 5650 7236 2351 -17 -120 O ATOM 1310 N SER B 321 5.933 14.292 -16.391 1.00 47.01 N ANISOU 1310 N SER B 321 6145 5184 6533 1852 -52 -200 N ATOM 1311 CA SER B 321 5.467 13.682 -17.637 1.00 46.52 C ANISOU 1311 CA SER B 321 5861 5338 6476 1841 -166 -97 C ATOM 1312 CB SER B 321 6.558 13.805 -18.715 1.00 45.54 C ANISOU 1312 CB SER B 321 5887 5120 6297 1664 -270 -17 C ATOM 1313 OG SER B 321 6.312 12.943 -19.816 1.00 45.99 O ANISOU 1313 OG SER B 321 5744 5402 6326 1586 -373 48 O ATOM 1314 C SER B 321 5.048 12.212 -17.426 1.00 44.12 C ANISOU 1314 C SER B 321 5267 5313 6185 1707 -153 -150 C ATOM 1315 O SER B 321 5.732 11.476 -16.721 1.00 42.89 O ANISOU 1315 O SER B 321 5134 5155 6007 1511 -100 -235 O ATOM 1316 N SER B 322 3.928 11.813 -18.037 1.00 43.82 N ANISOU 1316 N SER B 322 4963 5507 6179 1810 -209 -96 N ATOM 1317 CA SER B 322 3.371 10.454 -17.924 1.00 42.09 C ANISOU 1317 CA SER B 322 4461 5551 5981 1676 -201 -140 C ATOM 1318 CB SER B 322 2.114 10.463 -17.059 1.00 43.94 C ANISOU 1318 CB SER B 322 4489 5924 6284 1855 -88 -176 C ATOM 1319 OG SER B 322 2.445 10.678 -15.713 1.00 46.56 O ANISOU 1319 OG SER B 322 4969 6115 6605 186.

69. 271 O ATOM 1320 C SER B 322 2.996 9.800 -19.256 1.00 40.57 C ANISOU 1320 C SER B 322 4083 5563 5770 1602 -354 -68 C ATOM 1321 O SER B 322 2.599 10.477 -20.210 1.00 42.21 O ANISOU 1321 O SER B 322 4284 5791 5965 1754 -465 32 O ATOM 1322 N PHE B 323 3.081 8.475 -19.284 1.00 36.89 N ANISOU 1322 N PHE B 323 3479 5243 5295 1374 -362 -122 N ATOM 1323 CA PHE B 323 2.551 7.663 -20.374 1.00 36.10 C ANISOU 1323 CA PHE B 323 3178 5364 5176 1279 -495 -90 C ATOM 1324 CB PHE B 323 3.513 7.627 -21.574 1.00 34.59 C ANISOU 1324 CB PHE B 323 3153 5104 4888 1159 -613 -44 C ATOM 1325 CG PHE B 323 4.919 7.274 -21.200 1.00 30.95 C ANISOU 1325 CG PHE B 323 2900 4468 4391 973 -541 -102 C ATOM 1326 CD1 PHE B 323 5.340 5.953 -21.231 1.00 26.79 C ANISOU 1326 CD1 PHE B 323 2326 4009 3845 748 -533 -173 C ATOM 1327 CE1 PHE B 323 6.630 5.629 -20.870 1.00 28.42 C ANISOU 1327 CE1 PHE B 323 2700 4071 4027 608 -472 -218 C ATOM 1328 CZ PHE B 323 7.524 6.648 -20.464 1.00 28.42 C ANISOU 1328 CZ PHE B 323 2907 3870 4021 662 -426 -198 C ATOM 1329 CE2 PHE B 323 7.088 7.988 -20.442 1.00 27.51 C ANISOU 1329 CE2 PHE B 323 2862 3668 3922 862 -434 -134 C ATOM 1330 CD2 PHE B 323 5.813 8.277 -20.801 1.00 27.06 C ANISOU 1330 CD2 PHE B 323 2650 3742 3890 1028 -486 -86 C ATOM 1331 C PHE B 323 2.265 6.253 -19.873 1.00 35.08 C ANISOU 1331 C PHE B 323 2870 5383 5074 1071 -439 -175 C ATOM 1332 O PHE B 323 2.618 5.888 -18.744 1.00 33.74 O ANISOU 1332 O PHE B 323 2759 5134 4925 997 -303 -245 O ATOM 1333 N SER B 324 1.618 5.474 -20.725 1.00 35.51 N ANISOU 1333 N SER B 324 2724 5647 5120 971 -553 -167 N ATOM 1334 CA SER B 324 1.270 4.093 -20.446 1.00 35.61 C ANISOU 1334 CA SER B 324 2576 5797 5160 747 -521 -240 C ATOM 1335 CB SER B 324 -0.200 3.869 -20.791 1.00 38.02 C ANISOU 1335 CB SER B 324 2544 6381 5520 785 -594 -217 C ATOM 1336 OG SER B 324 -0.802 2.894 -19.960 1.00 41.46 O ANISOU 1336 OG SER B 324 2800 6931 6024 634 -483 -279 O ATOM 1337 C SER B 324 2.182 3.210 -21.320 1.00 33.97 C ANISOU 1337 C SER B 324 2498 5542 4866 521 -606 -273 C ATOM 1338 O SER B 324 2.389 3.498 -22.500 1.00 34.44 O ANISOU 1338 O SER B 324 2615 5622 4850 539 -742 -227 O ATOM 1339 N PHE B 325 2.760 2.167 -20.734 1.00 31.78 N ANISOU 1339 N PHE B 325 2289 5194 4592 327 -518 -348 N ATOM 1340 CA PHE B 325 3.513 1.176 -21.491 1.00 29.85 C ANISOU 1340 CA PHE B 325 2148 4915 4278 124 -577 -395 C ATOM 1341 CB PHE B 325 4.972 1.610 -21.693 1.00 28.12 C ANISOU 1341 CB PHE B 325 2192 4498 3995 143 -561 -383 C ATOM 1342 CG PHE B 325 5.770 0.673 -22.571 1.00 26.86 C ANISOU 1342 CG PHE B 325 2137 4311 3757 -27 -608 -429 C ATOM 1343 CD1 PHE B 325 5.458 0.518 -23.931 1.00 28.72 C ANISOU 1343 CD1 PHE B 325 2340 4663 3908 -68 -746 -422 C ATOM 1344 CE1 PHE B 325 6.190 -0.356 -24.743 1.00 28.43 C ANISOU 1344 CE1 PHE B 325 2420 4597 3784 -214 -772 -481 C ATOM 1345 CZ PHE B 325 7.263 -1.082 -24.196 1.00 26.96 C ANISOU 1345 CZ PHE B 325 2368 4261 3612 -302 -660 -539 C ATOM 1346 CE2 PHE B 325 7.581 -0.933 -22.850 1.00 23.52 C ANISOU 1346 CE2 PHE B 325 1951 3720 3265 -259 -543 -533 C ATOM 1347 CD2 PHE B 325 6.831 -0.057 -22.045 1.00 25.04 C ANISOU 1347 CD2 PHE B 325 2043 3944 3527 -131 -518 -483 C ATOM 1348 C PHE B 325 3.456 -0.162 -20.770 1.00 29.26 C ANISOU 1348 C PHE B 325 2036 4838 4242 -75 -486 -471 C ATOM 1349 O PHE B 325 3.759 -0.239 -19.586 1.00 27.73 O ANISOU 1349 O PHE B 325 1904 4545 4086 -67 -351 -485 O ATOM 1350 N GLY B 326 3.028 -1.202 -21.487 1.00 30.19 N ANISOU 1350 N GLY B 326 2067 5063 4339 -256 -565 -518 N ATOM 1351 CA GLY B 326 2.970 -2.562 -20.950 1.00 30.07 C ANISOU 1351 CA GLY B 326 2049 5020 4356 -471 -488 -587 C ATOM 1352 C GLY B 326 2.057 -2.782 -19.754 1.00 31.33 C ANISOU 1352 C GLY B 326 2041 5253 4609 -494 -364 -580 C ATOM 1353 O GLY B 326 2.288 -3.706 -18.964 1.00 30.80 O ANISOU 1353 O GLY B 326 2046 5095 4563 -632 -253 -612 O ATOM 1354 N GLY B 327 1.029 -1.938 -19.624 1.00 32.09 N ANISOU 1354 N GLY B 327 1922 5515 4756 -348 -374 -531 N ATOM 1355 CA GLY B 327 0.118 -1.987 -18.486 1.00 33.34 C ANISOU 1355 CA GLY B 327 1900 5769 4998 -337 -231 -519 C ATOM 1356 C GLY B 327 0.542 -1.183 -17.265 1.00 31.95 C ANISOU 1356 C GLY B 327 1846 5467 4829 -154 -76 -495 C ATOM 1357 O GLY B 327 -0.117 -1.257 -16.216 1.00 33.59 O ANISOU 1357 O GLY B 327 1940 5738 5083 -142.

73. 490 O ATOM 1358 N PHE B 328 1.609 -0.399 -17.411 1.00 29.32 N ANISOU 1358 N PHE B 328 1738 4962 4439 -22 -107 -482 N ATOM 1359 CA PHE B 328 2.156 0.428 -16.338 1.00 28.13 C ANISOU 1359 CA PHE B 328 1744 4669 4277 13.

12. 473 C ATOM 1360 CB PHE B 328 3.628 0.057 -16.050 1.00 25.60 C ANISOU 1360 CB PHE B 328 1698 4135 3894 5.

27. 499 C ATOM 1361 CG PHE B 328 3.793 -1.258 -15.358 1.00 25.59 C ANISOU 1361 CG PHE B 328 1733 4099 3890 -141 113 -529 C ATOM 1362 CD1 PHE B 328 3.840 -1.329 -13.968 1.00 25.50 C ANISOU 1362 CD1 PHE B 328 1790 4033 3866 -125 261 -531 C ATOM 1363 CE1 PHE B 328 3.965 -2.559 -13.319 1.00 24.09 C ANISOU 1363 CE1 PHE B 328 1665 3812 3675 -297 342 -539 C ATOM 1364 CZ PHE B 328 4.054 -3.706 -14.047 1.00 24.40 C ANISOU 1364 CZ PHE B 328 1699 3843 3728 -482 279 -556 C ATOM 1365 CE2 PHE B 328 4.005 -3.655 -15.450 1.00 25.53 C ANISOU 1365 CE2 PHE B 328 1777 4043 3882 -505 132 -574 C ATOM 1366 CD2 PHE B 328 3.876 -2.433 -16.092 1.00 24.35 C ANISOU 1366 CD2 PHE B 328 1565 3954 3731 -335.

49. 556 C ATOM 1367 C PHE B 328 2.093 1.894 -16.718 1.00 28.62 C ANISOU 1367 C PHE B 328 1826 4711 4336 382 -44 -429 C ATOM 1368 O PHE B 328 2.399 2.262 -17.854 1.00 28.17 O ANISOU 1368 O PHE B 328 1811 4646 4248 412 -185 -399 O ATOM 1369 N THR B 329 1.690 2.727 -15.760 1.00 29.74 N ANISOU 1369 N THR B 329 1959 4837 4502 56.

74. 425 N ATOM 1370 CA THR B 329 1.801 4.169 -15.900 1.00 29.75 C ANISOU 1370 CA THR B 329 2059 4747 4498 80.

49. 391 C ATOM 1371 CB THR B 329 0.751 4.914 -15.031 1.00 32.29 C ANISOU 1371 CB THR B 329 2253 5145 4871 1029 182 -390 C ATOM 1372 OG1 THR B 329 -0.576 4.482 -15.374 1.00 31.53 O ANISOU 1372 OG1 THR B 329 1818 5316 4846 1033 168 -364 O ATOM 1373 CG2 THR B 329 0.846 6.411 -15.230 1.00 31.75 C ANISOU 1373 CG2 THR B 329 2316 4948 4799 1297 153 -356 C ATOM 1374 C THR B 329 3.223 4.532 -15.485 1.00 28.41 C ANISOU 1374 C THR B 329 2200 4331 4263 78.

67. 416 C ATOM 1375 O THR B 329 3.629 4.259 -14.350 1.00 29.14 O ANISOU 1375 O THR B 329 2399 4343 4330 729 183 -463 O ATOM 1376 N PHE B 330 3.995 5.073 -16.429 1.00 27.40 N ANISOU 1376 N PHE B 330 2210 4099 4102 796 -52 -380 N ATOM 1377 CA PHE B 330 5.301 5.664 -16.167 1.00 25.35 C ANISOU 1377 CA PHE B 330 2219 3620 3794 784 -48 -393 C ATOM 1378 CB PHE B 330 6.178 5.570 -17.410 1.00 24.18 C ANISOU 1378 CB PHE B 330 2153 3429 3605 684 -174 -355 C ATOM 1379 CG PHE B 330 6.737 4.194 -17.671 1.00 21.46 C ANISOU 1379 CG PHE B 330 1782 3132 3238 468 -193 -390 C ATOM 1380 CD1 PHE B 330 8.110 3.963 -17.574 1.00 18.03 C ANISOU 1380 CD1 PHE B 330 1514 2572 2767 358 -191 -410 C ATOM 1381 CE1 PHE B 330 8.642 2.682 -17.836 1.00 18.22 C ANISOU 1381 CE1 PHE B 330 1523 2625 2773 192 -201 -442 C ATOM 1382 CZ PHE B 330 7.787 1.630 -18.182 1.00 18.84 C ANISOU 1382 CZ PHE B 330 1451 2841 2869 110 -215 -462 C ATOM 1383 CE2 PHE B 330 6.396 1.859 -18.267 1.00 18.39 C ANISOU 1383 CE2 PHE B 330 1214 2923 2849 186 -226 -444 C ATOM 1384 CD2 PHE B 330 5.895 3.134 -18.019 1.00 20.38 C ANISOU 1384 CD2 PHE B 330 1457 3165 3123 377 -214 -404 C ATOM 1385 C PHE B 330 5.142 7.118 -15.831 1.00 27.08 C ANISOU 1385 C PHE B 330 2554 3714 4019 1002 -376 C ATOM 1386 O PHE B 330 4.443 7.841 -16.532 1.00 28.76 O ANISOU 1386 O PHE B 330 2699 3969 4258 1167 -72 -316 O ATOM 1387 N LYS B 331 5.795 7.544 -14.756 1.00 27.03 N ANISOU 1387 N LYS B 331 2738 3549 3983 100.

70. 432 N ATOM 1388 CA LYS B 331 5.856 8.956 -14.420 1.00 29.58 C ANISOU 1388 CA LYS B 331 3242 3697 4301 118.

100. 435 C ATOM 1389 CB LYS B 331 5.064 9.247 -13.135 1.00 30.49 C ANISOU 1389 CB LYS B 331 3344 3823 4419 1336 253 -500 C ATOM 1390 CG LYS B 331 5.276 10.638 -12.593 1.00 34.42 C ANISOU 1390 CG LYS B 331 4088 4096 4893 1503 301 -536 C ATOM 1391 CD LYS B 331 4.335 10.970 -11.437 1.00 37.48 C ANISOU 1391 CD LYS B 331 4452 4511 5276 1692 469 -604 C ATOM 1392 CE LYS B 331 4.357 12.470 -11.157 1.00 44.58 C ANISOU 1392 CE LYS B 331 5601 5174 6164 1907 508 -635 C ATOM 1393 NZ LYS B 331 3.272 12.887 -10.223 1.00 50.24 N ANISOU 1393 NZ LYS B 331 6274 5932 6884 2152 684 -696 N ATOM 1394 C LYS B 331 7.324 9.355 -14.298 1.00 28.10 C ANISOU 1394 C LYS B 331 3311 3304 4062 106.

61. 456 C ATOM 1395 O LYS B 331 8.037 8.798 -13.466 1.00 27.89 O ANISOU 1395 O LYS B 331 3352 3249 3997 92.

98. 517 O ATOM 1396 N ARG B 332 7.787 10.293 -15.132 1.00 28.13 N ANISOU 1396 N ARG B 332 3451 3172 4064 1099 -16 -397 N ATOM 1397 CA ARG B 332 9.184 10.755 -15.057 1.00 27.45 C ANISOU 1397 CA ARG B 332 3590 2899 3940 958 -50 -412 C ATOM 1398 CB ARG B 332 9.671 11.403 -16.367 1.00 27.67 C ANISOU 1398 CB ARG B 332 3703 2846 3966 939 -143 -313 C ATOM 1399 CG ARG B 332 11.213 11.679 -16.389 1.00 27.23 C ANISOU 1399 CG ARG B 332 3826 2642 3879 736 -173 -321 C ATOM 1400 CD ARG B 332 11.712 12.014 -17.789 1.00 28.39 C ANISOU 1400 CD ARG B 332 4015 2763 4011 677 -245 -212 C ATOM 1401 NE ARG B 332 11.084 13.243 -18.288 1.00 31.78 N ANISOU 1401 NE ARG B 332 4571 3058 4448 859 -260 -132 N ATOM 1402 CZ ARG B 332 11.095 13.644 -19.557 1.00 31.92 C ANISOU 1402 CZ ARG B 332 4626 3063 4438 881 -322 -10 C ATOM 1403 NH1 ARG B 332 11.702 12.900 -20.497 1.00 29.06 N ANISOU 1403 NH1 ARG B 332 4180 2829 4034 723 -365 33 N ATOM 1404 NH2 ARG B 332 10.480 14.783 -19.881 1.00 27.89 N ANISOU 1404 NH2 ARG B 332 4251 2412 3935 1075 -335 69 N ATOM 1405 C ARG B 332 9.449 11.702 -13.890 1.00 28.06 C ANISOU 1405 C ARG B 332 3890 2780 3993 101.

19. 492 C ATOM 1406 O ARG B 332 8.854 12.786 -13.811 1.00 29.26 O ANISOU 1406 O ARG B 332 4150 2809 4160 120.

53. 486 O ATOM 1407 N THR B 333 10.387 11.304 -13.020 1.00 26.57 N ANISOU 1407 N THR B 333 3782 2555 3757 85.

30. 566 N ATOM 1408 CA THR B 333 10.701 12.072 -11.806 1.00 27.14 C ANISOU 1408 CA THR B 333 4076 2459 3779 86.

83. 664 C ATOM 1409 CB THR B 333 10.605 11.185 -10.551 1.00 26.57 C ANISOU 1409 CB THR B 333 3954 2494 3648 824 153 -747 C ATOM 1410 OG1 THR B 333 11.447 10.029 -10.706 1.00 26.24 O ANISOU 1410 OG1 THR B 333 3808 2566 3597 62.

88. 725 O ATOM 1411 CG2 THR B 333 9.165 10.725 -10.341 1.00 27.09 C ANISOU 1411 CG2 THR B 333 3835 2720 3738 992 259 -741 C ATOM 1412 C THR B 333 12.062 12.825 -11.844 1.00 26.96 C ANISOU 1412 C THR B 333 4273 2240 3731 70.

8. 680 C ATOM 1413 O THR B 333 12.273 13.724 -11.056 1.00 27.63 O ANISOU 1413 O THR B 333 4577 2144 3775 72.

33. 758 O ATOM 1414 N SER B 334 12.957 12.454 -12.768 1.00 25.38 N ANISOU 1414 N SER B 334 4008 2081 3552 536 -76 -610 N ATOM 1415 CA SER B 334 14.274 13.108 -12.964 1.00 25.51 C ANISOU 1415 CA SER B 334 4182 1950 3561 351 -143 -605 C ATOM 1416 CB SER B 334 15.373 12.428 -12.171 1.00 24.37 C ANISOU 1416 CB SER B 334 4014 1868 3377 157 -184 -671 C ATOM 1417 OG SER B 334 15.537 13.002 -10.926 1.00 29.53 O ANISOU 1417 OG SER B 334 4850 2400 3971 145 -173 -780 O ATOM 1418 C SER B 334 14.705 12.915 -14.375 1.00 24.24 C ANISOU 1418 C SER B 334 3928 1847 3436 271 -195 -492 C ATOM 1419 O SER B 334 14.323 11.934 -15.016 1.00 22.59 O ANISOU 1419 O SER B 334 3521 1822 3240 295 -199 -445 O ATOM 1420 N GLY B 335 15.562 13.811 -14.833 1.00 24.97 N ANISOU 1420 N GLY B 335 4172 1782 3533 151 -230 -453 N ATOM 1421 CA GLY B 335 16.223 13.648 -16.116 1.00 24.84 C ANISOU 1421 CA GLY B 335 4086 1821 352.

33. 264 -347 C ATOM 1422 C GLY B 335 15.352 14.058 -17.286 1.00 25.60 C ANISOU 1422 C GLY B 335 4192 1905 3631 188 -262 -234 C ATOM 1423 O GLY B 335 14.281 14.625 -17.106 1.00 27.00 O ANISOU 1423 O GLY B 335 4436 2007 3818 395 -241 -231 O ATOM 1424 N SER B 336 15.838 13.762 -18.487 1.00 25.43 N ANISOU 1424 N SER B 336 4099 1967 359.

95. 285 -138 N ATOM 1425 CA SER B 336 15.225 14.169 -19.749 1.00 26.34 C ANISOU 1425 CA SER B 336 4242 2078 3686 207 -303 -11 C ATOM 1426 CB SER B 336 15.484 15.656 -20.048 1.00 28.83 C ANISOU 1426 CB SER B 336 4827 2128 3998 202 -299 68 C ATOM 1427 OG SER B 336 16.856 16.025 -19.901 1.00 30.57 O ANISOU 1427 OG SER B 336 5147 2245 4224 -53 -286 57 O ATOM 1428 C SER B 336 15.816 13.280 -20.832 1.00 25.42 C ANISOU 1428 C SER B 336 3985 2145 353.

81. 316 46 C ATOM 1429 O SER B 336 16.779 12.541 -20.571 1.00 23.98 O ANISOU 1429 O SER B 336 3706 2050 3355 -85 -301 -9 O ATOM 1430 N SER B 337 15.231 13.301 -22.031 1.00 25.43 N ANISOU 1430 N SER B 337 3968 2213 3481 171 -346 151 N ATOM 1431 CA SER B 337 15.828 12.576 -23.140 1.00 24.60 C ANISOU 1431 CA SER B 337 3774 2261 3312.

52. 346 201 C ATOM 1432 CB SER B 337 15.457 11.084 -23.140 1.00 23.13 C ANISOU 1432 CB SER B 337 3365 2304 312.

64. 359 122 C ATOM 1433 OG SER B 337 14.075 10.828 -23.373 1.00 25.51 O ANISOU 1433 OG SER B 337 3581 2702 3411 240 -413 131 O ATOM 1434 C SER B 337 15.505 13.216 -24.460 1.00 26.16 C ANISOU 1434 C SER B 337 4078 2434 3427 115 -376 348 C ATOM 1435 O SER B 337 14.583 14.017 -24.556 1.00 27.15 O ANISOU 1435 O SER B 337 4301 2463 3552 294 -417 413 O ATOM 1436 N ILE B 338 16.325 12.882 -25.455 1.00 26.35 N ANISOU 1436 N ILE B 338 4093 2544 3376 -27 -349 404 N ATOM 1437 CA ILE B 338 16.075 13.222 -26.849 1.00 27.55 C

ANISOU 1437 CA ILE B 338 4332 2727 3410 14 -377 545 C

ATOM 1438 CB ILE B 338 17.191 14.129 -27.454 1.00 28.81 C

ANISOU 1438 CB ILE B 338 4678 2747 3523 -152 -306 660 C

ATOM 1439 CG1 ILE B 338 18.579 13.472 -27.383 1.00 26.68 C

ANISOU 1439 CG1 ILE B 338 4302 2568 3268 -384 -214 597 C

ATOM 1440 CD1 ILE B 338 19.665 14.286 -28.122 1.00 28.93 C

ANISOU 1440 CD1 ILE B 338 4733 2760 3499 -571 -128 723 C

ATOM 1441 CG2 ILE B 338 17.170 15.486 -26.777 1.00 29.60 C

ANISOU 1441 CG2 ILE B 338 4987 2564 3694 -128 -302 701 C

ATOM 1442 C ILE B 338 15.884 11.899 -27.586 1.00 26.88 C

ANISOU 1442 C ILE B 338 4074 2894 3245 3 -398 501 C

ATOM 1443 O ILE B 338 16.186 10.856 -27.040 1.00 24.81 O

ANISOU 1443 O ILE B 338 3658 2737 3031 -63 -370 378 O

ATOM 1444 N LYS B 339 15.351 11.936 -28.800 1.00 29.34 N

ANISOU 1444 N LYS B 339 4428 3294 3428 73 -455 600 N

ATOM 1445 CA LYS B 339 15.109 10.715 -29.550 1.00 29.97 C

ANISOU 1445 CA LYS B 339 4375 3601 3413 56 -486 546 C

ATOM 1446 CB LYS B 339 13.657 10.595 -30.002 1.00 31.00 C

ANISOU 1446 CB LYS B 339 4446 3844 3489 232 -625 574 C

ATOM 1447 CG LYS B 339 12.575 10.731 -28.976 1.00 33.08 C

ANISOU 1447 CG LYS B 339 4606 4083 3882 388 -683 524 C

ATOM 1448 CD LYS B 339 11.246 10.804 -29.743 1.00 39.25 C

ANISOU 1448 CD LYS B 339 5331 4998 4584 558 -828 596 C

ATOM 1449 CE LYS B 339 10.060 11.092 -28.864 1.00 42.38 C

ANISOU 1449 CE LYS B 339 5609 5391 5103 748 -881 574 C

ATOM 1450 NZ LYS B 339 8.914 11.502 -29.728 1.00 47.09 N

ANISOU 1450 NZ LYS B 339 6177 6097 5618 936 -1030 689 N

ATOM 1451 C LYS B 339 15.927 10.747 -30.817 1.00 31.76 C

ANISOU 1451 C LYS B 339 4705 3878 3485 -58 -431 632 C

ATOM 1452 O LYS B 339 16.135 11.812 -31.422 1.00 33.75 O

ANISOU 1452 O LYS B 339 5140 4018 3664 -59 -419 782 O

ATOM 1453 N ARG B 340 16.350 9.566 -31.237 1.00 31.26 N

ANISOU 1453 N ARG B 340 4539 3977 3361 -146 -389 540 N

ATOM 1454 CA ARG B 340 16.998 9.401 -32.494 1.00 33.42 C

ANISOU 1454 CA ARG B 340 4895 4340 3462 -234 -327 598 C

ATOM 1455 CB ARG B 340 18.495 9.339 -32.275 1.00 33.24 C

ANISOU 1455 CB ARG B 340 4857 4283 3488 -401 -164 576 C

ATOM 1456 CG ARG B 340 19.324 9.305 -33.537 1.00 37.60 C

ANISOU 1456 CG ARG B 340 5499 4922 3866 -502 -54 648 C

ATOM 1457 CD ARG B 340 20.659 8.729 -33.170 1.00 40.36 C

ANISOU 1457 CD ARG B 340 5728 5314 4294 -636 100 564 C

ATOM 1458 NE ARG B 340 21.646 8.866 -34.226 1.00 47.19 N

ANISOU 1458 NE ARG B 340 6660 6250 5019 -750 249 643 N

ATOM 1459 CZ ARG B 340 22.821 8.236 -34.223 1.00 50.98 C

ANISOU 1459 CZ ARG B 340 7018 6824 5528 -847 401 575 C

ATOM 1460 NH1 ARG B 340 23.142 7.436 -33.197 1.00 49.64 N

ANISOU 1460 NH1 ARG B 340 6666 6673 5521 -835 403 436 N

ATOM 1461 NH2 ARG B 340 23.677 8.409 -35.235 1.00 52.82 N

ANISOU 1461 NH2 ARG B 340 7309 7137 5623 -947 557 654 N

ATOM 1462 C ARG B 340 16.484 8.111 -33.093 1.00 33.37 C

ANISOU 1462 C ARG B 340 4794 4530 3355 -214 -380 492 C

ATOM 1463 O ARG B 340 16.559 7.042 -32.483 1.00 31.57 O

ANISOU 1463 O ARG B 340 4424 4358 3211 -242 -359 344 O

ATOM 1464 N GLU B 341 15.934 8.230 -34.287 1.00 35.28 N

ANISOU 1464 N GLU B 341 5133 4866 3405 -168 -458 572 N

ATOM 1465 CA GLU B 341 15.436 7.081 -34.986 1.00 35.48 C

ANISOU 1465 CA GLU B 341 5103 5074 3304 -171 -522 469 C

ATOM 1466 CB GLU B 341 14.512 7.527 -36.105 1.00 37.67 C

ANISOU 1466 CB GLU B 341 5486 5442 3384 -83 -672 584 C

ATOM 1467 CG GLU B 341 14.003 6.403 -36.917 1.00 39.18 C

ANISOU 1467 CG GLU B 341 5645 5825 3415 -110 -756 475 C

ATOM 1468 CD GLU B 341 12.728 6.772 -37.589 1.00 43.97 C

ANISOU 1468 CD GLU B 341 6272 6540 3896 5 -971 563 C

ATOM 1469 OE1 GLU B 341 12.775 7.040 -38.814 1.00 45.83 O

ANISOU 1469 OE1 GLU B 341 6670 6857 388.

4. 1010 659 O ATOM 1470 OE2 GLU B 341 11.690 6.807 -36.876 1.00 44.98 O ANISOU 1470 OE2 GLU B 341 6245 6681 4165 102 -1097 541 O ATOM 1471 C GLU B 341 16.615 6.290 -35.516 1.00 35.17 C ANISOU 1471 C GLU B 341 5086 5099 3177 -298 -363 393 C ATOM 1472 O GLU B 341 17.472 6.835 -36.209 1.00 37.32 O ANISOU 1472 O GLU B 341 5483 5357 3339 -362 -251 492 O ATOM 1473 N GLU B 342 16.644 5.013 -35.154 1.00 33.75 N ANISOU 1473 N GLU B 342 4787 4983 3052 -329 -342 219 N ATOM 1474 CA GLU B 342 17.705 4.076 -35.501 1.00 33.58 C ANISOU 1474 CA GLU B 342 4763 5018 2979 -412 -187 115 C ATOM 1475 CB GLU B 342 18.534 3.739 -34.259 1.00 32.29 C ANISOU 1475 CB GLU B 342 4466 4768 3036 -442 -80 40 C ATOM 1476 CG GLU B 342 19.606 4.754 -33.977 1.00 34.89 C ANISOU 1476 CG GLU B 342 4812 5012 3434 -500 36 153 C ATOM 1477 CD GLU B 342 20.496 4.362 -32.851 1.00 37.32 C ANISOU 1477 CD GLU B 342 4979 5269 3931 -536 124 77 C ATOM 1478 OE1 GLU B 342 20.843 5.278 -32.069 1.00 41.51 O ANISOU 1478 OE1 GLU B 342 5491 5694 4587 -569 129 148 O ATOM 1479 OE2 GLU B 342 20.843 3.159 -32.724 1.00 37.32 O ANISOU 1479 OE2 GLU B 342 4900 5327 3954 -527 180 -53 O ATOM 1480 C GLU B 342 17.091 2.790 -35.997 1.00 33.24 C ANISOU 1480 C GLU B 342 4709 5088 2833 -414 -253 -36 C ATOM 1481 O GLU B 342 15.936 2.497 -35.709 1.00 32.03 O ANISOU 1481 O GLU B 342 4490 4961 2718 -376 -409 -82 O ATOM 1482 N GLU B 343 17.874 2.026 -36.750 1.00 33.79 N ANISOU 1482 N GLU B 343 4844 5224 2771 -463 -125 -118 N ATOM 1483 CA GLU B 343 17.505 0.666 -37.091 1.00 33.29 C ANISOU 1483 CA GLU B 343 4790 5227 2632 -481 -154 -296 C ATOM 1484 CB GLU B 343 17.416 0.491 -38.604 1.00 36.07 C ANISOU 1484 CB GLU B 343 5318 5705 2683 -507 -163 -306 C ATOM 1485 CG GLU B 343 16.227 1.164 -39.223 1.00 38.05 C ANISOU 1485 CG GLU B 343 5629 6034 2792 -482 -375 -205 C ATOM 1486 CD GLU B 343 16.323 1.206 -40.720 1.00 44.38 C ANISOU 1486 CD GLU B 343 6631 6962 3270 -507 -371 -179 C ATOM 1487 OE1 GLU B 343 17.386 1.640 -41.255 1.00 46.93 O ANISOU 1487 OE1 GLU B 343 7056 7285 3489 -524 -186 -100 O ATOM 1488 OE2 GLU B 343 15.327 0.808 -41.360 1.00 46.73 O ANISOU 1488 OE2 GLU B 343 6979 7369 3409 -518 -553 -236 O ATOM 1489 C GLU B 343 18.493 -0.319 -36.484 1.00 31.64 C ANISOU 1489 C GLU B 343 4511 4962 2549 -492.

10. 426 C ATOM 1490 O GLU B 343 19.706 -0.165 -36.609 1.00 31.47 O ANISOU 1490 O GLU B 343 4491 4938 2528 -499 188 -397 O ATOM 1491 N VAL B 344 17.937 -1.331 -35.831 1.00 30.29 N ANISOU 1491 N VAL B 344 4273 4751 2484 -492 -54 -560 N ATOM 1492 CA VAL B 344 18.689 -2.310 -35.054 1.00 28.25 C ANISOU 1492 CA VAL B 344 3947 4413 2372 -477.

67. 673 C ATOM 1493 CB VAL B 344 18.436 -2.166 -33.514 1.00 26.46 C ANISOU 1493 CB VAL B 344 3570 4085 2396 -456.

14. 647 C ATOM 1494 CG1 VAL B 344 18.841 -0.786 -33.009 1.00 25.57 C ANISOU 1494 CG1 VAL B 344 3398 3945 2372 -442.

27. 489 C ATOM 1495 CG2 VAL B 344 16.977 -2.489 -33.150 1.00 24.38 C ANISOU 1495 CG2 VAL B 344 3272 3821 2170 -479 -160 -691 C ATOM 1496 C VAL B 344 18.313 -3.718 -35.484 1.00 28.72 C ANISOU 1496 C VAL B 344 4091 4473 2347 -501.

54. 854 C ATOM 1497 O VAL B 344 17.259 -3.928 -36.106 1.00 29.90 O ANISOU 1497 O VAL B 344 4309 4683 2368 -553 -89 -899 O ATOM 1498 N LEU B 345 19.158 -4.685 -35.122 1.00 27.67 N ANISOU 1498 N LEU B 345 3954 4268 2292 -464 195 -959 N ATOM 1499 CA LEU B 345 19.009 -6.054 -35.598 1.00 28.06 C ANISOU 1499 CA LEU B 345 4127 4281 2253 -479 220 -1141 C ATOM 1500 CB LEU B 345 20.251 -6.481 -36.379 1.00 28.98 C ANISOU 1500 CB LEU B 345 4335 4421 2254 -413 431 -1204 C ATOM 1501 CG LEU B 345 20.407 -5.803 -37.751 1.00 30.75 C ANISOU 1501 CG LEU B 345 4677 4787 2220 -439 469 -1154 C ATOM 1502 CD1 LEU B 345 21.733 -6.157 -38.415 1.00 30.52 C ANISOU 1502 CD1 LEU B 345 4708 4796 2093 -363 717 -1205 C ATOM 1503 CD2 LEU B 345 19.278 -6.215 -38.670 1.00 32.27 C ANISOU 1503 CD2 LEU B 345 5033 5030 2199 -522 316 -1251 C ATOM 1504 C LEU B 345 18.720 -6.985 -34.436 1.00 27.04 C ANISOU 1504 C LEU B 345 3939 4015 2320 -476 193 -1220 C ATOM 1505 O LEU B 345 19.387 -6.910 -33.389 1.00 25.76 O ANISOU 1505 O LEU B 345 3661 3784 2342 -410 262 -1167 O ATOM 1506 N THR B 346 17.695 -7.823 -34.588 1.00 26.96 N ANISOU 1506 N THR B 346 4007 3970 2268 -562.

81. 1336 N ATOM 1507 CA THR B 346 17.350 -8.749 -33.512 1.00 26.28 C ANISOU 1507 CA THR B 346 3888 3741 2355 -582.

62. 1403 C ATOM 1508 CB THR B 346 15.887 -9.268 -33.635 1.00 26.91 C ANISOU 1508 CB THR B 346 4000 3826 2400 -731 -111 -1483 C ATOM 1509 OG1 THR B 346 15.764 -10.147 -34.762 1.00 25.20 O ANISOU 1509 OG1 THR B 346 3979 3603 1992 -799 -110 -1646 O ATOM 1510 CG2 THR B 346 14.906 -8.098 -33.746 1.00 25.10 C ANISOU 1510 CG2 THR B 346 3644 3748 2145 -775 -277 -1361 C ATOM 1511 C THR B 346 18.348 -9.919 -33.460 1.00 27.87 C ANISOU 1511 C THR B 346 4198 3808 2581 -499 229 -1520 C ATOM 1512 O THR B 346 19.239 -10.033 -34.325 1.00 29.40 O ANISOU 1512 O THR B 346 4483 4038 2650 -427 363 -1567 O ATOM 1513 N GLY B 347 18.192 -10.779 -32.459 1.00 27.20 N ANISOU 1513 N GLY B 347 4111 3571 2653 -499 231 -1563 N ATOM 1514 CA GLY B 347 18.936 -12.031 -32.387 1.00 29.00 C ANISOU 1514 CA GLY B 347 4473 3639 2908 -413 367 -1680 C ATOM 1515 C GLY B 347 18.678 -12.996 -33.546 1.00 32.22 C ANISOU 1515 C GLY B 347 5117 3994 3132 -473 388 -1868 C ATOM 1516 O GLY B 347 19.373 -14.017 -33.671 1.00 33.15 O ANISOU 1516 O GLY B 347 5381 3967 3245 -376 523 -1981 O ATOM 1517 N ASN B 348 17.675 -12.677 -34.381 1.00 32.97 N ANISOU 1517 N ASN B 348 5255 4201 3069 -625 248 -1904 N ATOM 1518 CA ASN B 348 17.405 -13.400 -35.631 1.00 35.54 C ANISOU 1518 CA ASN B 348 5814 4519 3172 -705 242 -2083 C ATOM 1519 CB ASN B 348 15.971 -13.938 -35.629 1.00 36.61 C ANISOU 1519 CB ASN B 348 5999 4622 3290 -925.

51. 2171 C ATOM 1520 CG ASN B 348 15.795 -15.108 -36.571 1.00 39.61 C ANISOU 1520 CG ASN B 348 6662 4895 3493 -1018.

63. 2399 C ATOM 1521 OD1 ASN B 348 16.626 -16.016 -36.596 1.00 43.16 O ANISOU 1521 OD1 ASN B 348 7285 5163 3950 -910 232 -2509 O ATOM 1522 ND2 ASN B 348 14.725 -15.085 -37.373 1.00 40.71 N ANISOU 1522 ND2 ASN B 348 6855 5147 3464 -1211 -120 -2476 N ATOM 1523 C ASN B 348 17.667 -12.572 -36.916 1.00 36.61 C ANISOU 1523 C ASN B 348 5990 4852 3067 -687 255 -2062 C ATOM 1524 O ASN B 348 17.122 -12.874 -37.983 1.00 38.05 O ANISOU 1524 O ASN B 348 6341 5088 3030 -793 181 -2183 O ATOM 1525 N LEU B 349 18.513 -11.541 -36.785 1.00 35.54 N ANISOU 1525 N LEU B 349 5710 4822 2971 -566 347 -1905 N ATOM 1526 CA LEU B 349 18.816 -10.526 -37.819 1.00 36.28 C ANISOU 1526 CA LEU B 349 5813 5105 2868 -550 371 -1824 C ATOM 1527 CB LEU B 349 19.731 -11.063 -38.920 1.00 38.60 C ANISOU 1527 CB LEU B 349 6300 5411 2954 -470 564 -1949 C ATOM 1528 CG LEU B 349 21.223 -11.340 -38.716 1.00 39.26 C ANISOU 1528 CG LEU B 349 6348 5448 3121 -285 826 -1953 C ATOM 1529 CD1 LEU B 349 21.879 -11.427 -40.098 1.00 42.73 C ANISOU 1529 CD1 LEU B 349 6964 5987 3283 -234 995 -2038 C ATOM 1530 CD2 LEU B 349 21.941 -10.323 -37.866 1.00 36.33 C ANISOU 1530 CD2 LEU B 349 5719 5139 2944 -211 877 -1751 C ATOM 1531 C LEU B 349 17.624 -9.803 -38.446 1.00 36.73 C ANISOU 1531 C LEU B 349 5872 5311 2775 -684 152 -1771 C ATOM 1532 O LEU B 349 17.698 -9.335 -39.579 1.00 38.72 O ANISOU 1532 O LEU B 349 6228 5696 2787 -694 154 -1759 O ATOM 1533 N GLN B 350 16.522 -9.716 -37.721 1.00 35.55 N ANISOU 1533 N GLN B 350 5604 5147 2756 -777 -33 -1735 N ATOM 1534 CA GLN B 350 15.386 -8.965 -38.230 1.00 36.17 C ANISOU 1534 CA GLN B 350 5639 5385 2719 -874 -250 -1664 C ATOM 1535 CB GLN B 350 14.078 -9.409 -37.570 1.00 35.38 C ANISOU 1535 CB GLN B 350 5441 5259 2744 -1005 -437 -1706 C ATOM 1536 CG GLN B 350 12.839 -8.730 -38.162 1.00 37.56 C ANISOU 1536 CG GLN B 350 5649 5725 2896 -1094 -678 -1646 C ATOM 1537 CD GLN B 350 11.541 -9.112 -37.450 1.00 37.75 C ANISOU 1537 CD GLN B 350 5522 5756 3067 -1225 -850 -1674 C ATOM 1538 OE1 GLN B 350 11.541 -9.925 -36.534 1.00 37.89 O ANISOU 1538 OE1 GLN B 350 5514 5620 3264 -1269 -784 -1742 O ATOM 1539 NE2 GLN B 350 10.433 -8.514 -37.872 1.00 38.46 N ANISOU 1539 NE2 GLN B 350 5505 6031 3077 -1284 -1067 -1612 N ATOM 1540 C GLN B 350 15.641 -7.495 -37.930 1.00 34.39 C ANISOU 1540 C GLN B 350 5259 5249 2560 -786 -250 -1441 C ATOM 1541 O GLN B 350 15.987 -7.132 -36.801 1.00 32.10 O ANISOU 1541 O GLN B 350 4817 4883 2495 -722 -194 -1348 O ATOM 1542 N THR B 351 15.480 -6.654 -38.937 1.00 35.51 N ANISOU 1542 N THR B 351 5460 5538 2492 -786 -314 -1357 N ATOM 1543 CA THR B 351 15.638 -5.218 -38.753 1.00 35.15 C ANISOU 1543 CA THR B 351 5308 5556 2491 -715 -325 -1141 C ATOM 1544 CB THR B 351 15.876 -4.493 -40.090 1.00 36.33 C ANISOU 1544 CB THR B 351 5605 5840 2357 -703 -319 -1061 C ATOM 1545 OG1 THR B 351 17.037 -5.035 -40.720 1.00 36.38 O ANISOU 1545 OG1 THR B 351 5755 5831 2237 -677 -97 -1150 O ATOM 1546 CG2 THR B 351 16.109 -3.013 -39.855 1.00 35.19 C ANISOU 1546 CG2 THR B 351 5379 5719 2273 -636 -312 -830 C ATOM 1547 C THR B 351 14.428 -4.602 -38.066 1.00 34.79 C ANISOU 1547 C THR B 351 5095 5543 2579 -732 -530 -1043 C ATOM 1548 O THR B 351 13.297 -4.781 -38.513 1.00 36.32 O ANISOU 1548 O THR B 351 5289 5835 2677 -804 -723 -1083 O ATOM 1549 N LEU B 352 14.669 -3.878 -36.979 1.00 33.75 N ANISOU 1549 N LEU B 352 4817 5341 2667 -663 -487 -922 N ATOM 1550 CA LEU B 352 13.622 -3.070 -36.344 1.00 34.12 C ANISOU 1550 CA LEU B 352 4710 5420 2832 -640 -648 -808 C ATOM 1551 CB LEU B 352 13.362 -3.513 -34.889 1.00 32.44 C ANISOU 1551 CB LEU B 352 4345 5100 2881 -645 -632 -847 C ATOM 1552 CG LEU B 352 12.886 -4.942 -34.597 1.00 32.96 C ANISOU 1552 CG LEU B 352 4408 5119 2994 -749 -654 -1020 C ATOM 1553 CD1 LEU B 352 12.818 -5.103 -33.090 1.00 32.72 C ANISOU 1553 CD1 LEU B 352 4242 4977 3214 -731 -607 -1006 C ATOM 1554 CD2 LEU B 352 11.534 -5.282 -35.237 1.00 34.08 C ANISOU 1554 CD2 LEU B 352 4529 5392 3028 -855 -857 -1081 C ATOM 1555 C LEU B 352 13.996 -1.589 -36.370 1.00 33.77 C ANISOU 1555 C LEU B 352 4660 5383 2790 -547 -626 -610 C ATOM 1556 O LEU B 352 15.095 -1.217 -35.983 1.00 33.03 O ANISOU 1556 O LEU B 352 4572 5204 2773 -512 -465 -558 O ATOM 1557 N LYS B 353 13.074 -0.753 -36.832 1.00 35.44 N ANISOU 1557 N LYS B 353 4859 5692 2916 -511 -793 -499 N ATOM 1558 CA LYS B 353 13.235 0.694 -36.758 1.00 35.60 C ANISOU 1558 CA LYS B 353 4887 5683 2957 -416 -792 -303 C ATOM 1559 CB LYS B 353 12.510 1.355 -37.917 1.00 37.98 C ANISOU 1559 CB LYS B 353 5277 6118 3036 -378 -955 -195 C ATOM 1560 CG LYS B 353 12.989 2.760 -38.252 1.00 40.38 C ANISOU 1560 CG LYS B 353 5690 6373 3280 -298 -911 12 C ATOM 1561 CD LYS B 353 12.251 3.271 -39.513 1.00 47.52 C ANISOU 1561 CD LYS B 353 6709 7420 3925 -254 -1086 121 C ATOM 1562 CE LYS B 353 13.174 4.063 -40.450 1.00 51.30 C ANISOU 1562 CE LYS B 353 7408 7878 4205 -253 -970 266 C ATOM 1563 NZ LYS B 353 12.550 4.327 -41.795 1.00 55.38 N ANISOU 1563 NZ LYS B 353 8074 8553 4416 -224 -1134 354 N ATOM 1564 C LYS B 353 12.636 1.177 -35.441 1.00 34.34 C ANISOU 1564 C LYS B 353 4557 5448 3042 -351 -841 -254 C ATOM 1565 O LYS B 353 11.425 1.077 -35.231 1.00 34.90 O ANISOU 1565 O LYS B 353 4510 5595 3155 -331 -997 -267 O ATOM 1566 N ILE B 354 13.478 1.693 -34.559 1.00 32.69 N ANISOU 1566 N ILE B 354 4329 5103 2987 -322 -706 -204 N ATOM 1567 CA ILE B 354 13.045 2.177 -33.262 1.00 31.87 C ANISOU 1567 CA ILE B 354 4097 4914 3098 -258 -726 -169 C ATOM 1568 CB ILE B 354 13.522 1.253 -32.057 1.00 29.83 C ANISOU 1568 CB ILE B 354 3748 4568 3018 -309 -619 -293 C ATOM 1569 CG1 ILE B 354 15.045 1.231 -31.936 1.00 29.97 C ANISOU 1569 CG1 ILE B 354 3830 4502 3055 -342 -447 -296 C ATOM 1570 CD1 ILE B 354 15.560 0.674 -30.576 1.00 28.39 C ANISOU 1570 CD1 ILE B 354 3540 4204 3043 -353 -362 -368 C ATOM 1571 CG2 ILE B 354 12.948 -0.182 -32.167 1.00 28.73 C ANISOU 1571 CG2 ILE B 354 3563 4495 2859 -389 -663 -447 C ATOM 1572 C ILE B 354 13.526 3.621 -33.042 1.00 32.17 C ANISOU 1572 C ILE B 354 4202 4845 3176 -186 -681 -10 C ATOM 1573 O ILE B 354 14.521 4.069 -33.643 1.00 32.57 O ANISOU 1573 O ILE B 354 4377 4863 3134 -221 -582 57 O ATOM 1574 N ARG B 355 12.815 4.352 -32.186 1.00 31.65 N ANISOU 1574 N ARG B 355 4061 4720 3243 -91 -742 48 N ATOM 1575 CA ARG B 355 13.288 5.641 -31.749 1.00 32.09 C ANISOU 1575 CA ARG B 355 4195 4629 3367 -34 -689 170 C ATOM 1576 CB ARG B 355 12.149 6.642 -31.605 1.00 34.12 C ANISOU 1576 CB ARG B 355 4439 4870 3656 122 -811 276 C ATOM 1577 CG ARG B 355 11.544 7.019 -32.964 1.00 40.68 C ANISOU 1577 CG ARG B 355 5351 5813 4294 184 -940 384 C ATOM 1578 CD ARG B 355 10.425 7.984 -32.784 1.00 49.99 C ANISOU 1578 CD ARG B 355 6500 6978 5518 372 -1063 495 C ATOM 1579 NE ARG B 355 9.347 7.782 -33.751 1.00 57.85 N ANISOU 1579 NE ARG B 355 7438 8169 6374 442 -1246 533 N ATOM 1580 CZ ARG B 355 8.140 8.351 -33.661 1.00 61.98 C ANISOU 1580 CZ ARG B 355 7861 8751 6936 624 -1388 610 C ATOM 1581 NH1 ARG B 355 7.842 9.147 -32.628 1.00 61.47 N ANISOU 1581 NH1 ARG B 355 7761 8550 7045 765 -1346 648 N ATOM 1582 NH2 ARG B 355 7.220 8.116 -34.599 1.00 64.39 N ANISOU 1582 NH2 ARG B 355 8099 9264 7103 672 -1573 644 N ATOM 1583 C ARG B 355 14.040 5.442 -30.452 1.00 29.39 C ANISOU 1583 C ARG B 355 3795 4172 3199 -82 -573 96 C ATOM 1584 O ARG B 355 13.448 5.166 -29.416 1.00 29.13 O ANISOU 1584 O ARG B 355 3651 4123 3296 -44 -595 33 O ATOM 1585 N VAL B 356 15.361 5.534 -30.531 1.00 27.06 N ANISOU 1585 N VAL B 356 3568 3818 2896 -173 -448 106 N ATOM 1586 CA VAL B 356 16.203 5.352 -29.374 1.00 24.71 C ANISOU 1586 CA VAL B 356 3213 3431 2745 -225 -354 44 C ATOM 1587 CB VAL B 356 17.660 4.989 -29.781 1.00 24.66 C ANISOU 1587 CB VAL B 356 3228 3443 2701 -334 -221 27 C ATOM 1588 CG1 VAL B 356 18.584 4.978 -28.570 1.00 22.93 C ANISOU 1588 CG1 VAL B 356 2938 3141 2632 -383 -149 -14 C ATOM 1589 CG2 VAL B 356 17.691 3.637 -30.499 1.00 24.39 C ANISOU 1589 CG2 VAL B 356 3163 3532 2572 -358 -198 -77 C ATOM 1590 C VAL B 356 16.195 6.627 -28.548 1.00 24.03 C ANISOU 1590 C VAL B 356 3178 3194 2758 -182 -360 122 C ATOM 1591 O VAL B 356 16.500 7.679 -29.070 1.00 25.01 O ANISOU 1591 O VAL B 356 3429 3245 2830 -189 -348 238 O ATOM 1592 N HIS B 357 15.853 6.512 -27.266 1.00 21.94 N ANISOU 1592 N HIS B 357 2836 2873 2626 -144 -371 56 N ATOM 1593 CA HIS B 357 15.871 7.643 -26.336 1.00 21.71 C ANISOU 1593 CA HIS B 357 2873 2687 2689 -106 -368 97 C ATOM 1594 CB HIS B 357 14.798 7.476 -25.251 1.00 20.79 C ANISOU 1594 CB HIS B 357 2672 2563 266.

2. 412 33 C ATOM 1595 CG HIS B 357 13.410 7.756 -25.737 1.00 21.75 C ANISOU 1595 CG HIS B 357 2767 2747 2751 144 -503 82 C ATOM 1596 ND1 HIS B 357 12.706 8.884 -25.371 1.00 23.54 N ANISOU 1596 ND1 HIS B 357 3056 2871 3017 287 -534 145 N ATOM 1597 CE1 HIS B 357 11.530 8.882 -25.974 1.00 22.53 C ANISOU 1597 CE1 HIS B 357 2858 2853 2849 411 -626 188 C ATOM 1598 NE2 HIS B 357 11.450 7.797 -26.723 1.00 23.39 N ANISOU 1598 NE2 HIS B 357 2873 3128 2886 329 -662 148 N ATOM 1599 CD2 HIS B 357 12.613 7.077 -26.595 1.00 22.62 C ANISOU 1599 CD2 HIS B 357 2792 3016 2786 170 -577 78 C ATOM 1600 C HIS B 357 17.247 7.801 -25.708 1.00 20.95 C ANISOU 1600 C HIS B 357 2796 2511 2655 -232 -283 74 C ATOM 1601 O HIS B 357 17.824 6.843 -25.188 1.00 18.76 O ANISOU 1601 O HIS B 357 2417 2290 2421 -290 -244 -15 O ATOM 1602 N GLU B 358 17.764 9.024 -25.773 1.00 21.60 N ANISOU 1602 N GLU B 358 3009 2459 2740 -276 -262 161 N ATOM 1603 CA GLU B 358 19.132 9.306 -25.328 1.00 21.12 C ANISOU 1603 CA GLU B 358 2957 2337 2730 -429 -192 153 C ATOM 1604 CB GLU B 358 19.907 9.942 -26.477 1.00 22.08 C ANISOU 1604 CB GLU B 358 3175 2446 2769 -535 -131 268 C ATOM 1605 CG GLU B 358 20.023 9.004 -27.665 1.00 22.15 C ANISOU 1605 CG GLU B 358 3121 2631 2664 -539 -93 272 C ATOM 1606 CD GLU B 358 20.615 9.629 -28.884 1.00 24.08 C ANISOU 1606 CD GLU B 358 3477 2879 2794 -626 -23 397 C ATOM 1607 OE1 GLU B 358 20.524 10.875 -29.048 1.00 23.87 O ANISOU 1607 OE1 GLU B 358 3613 2702 2753 -643 -34 513 O ATOM 1608 OE2 GLU B 358 21.157 8.845 -29.705 1.00 25.65 O ANISOU 1608 OE2 GLU B 358 3616 3224 2907 -671 52 379 O ATOM 1609 C GLU B 358 19.112 10.217 -24.111 1.00 21.14 C ANISOU 1609 C GLU B 358 3040 2167 2824 -430 -215 132 C ATOM 1610 O GLU B 358 18.544 11.303 -24.159 1.00 21.17 O ANISOU 1610 O GLU B 358 3194 2027 2822 -362 -242 198 O ATOM 1611 N GLY B 359 19.685 9.752 -23.008 1.00 20.16 N ANISOU 1611 N GLY B 359 2830 2055 2773 -490 -208 36 N ATOM 1612 CA GLY B 359 19.778 10.572 -21.819 1.00 20.57 C ANISOU 1612 CA GLY B 359 2974 1953 2890 -512 -231 -3 C ATOM 1613 C GLY B 359 19.326 9.821 -20.596 1.00 19.73 C ANISOU 1613 C GLY B 359 2783 1889 2826 -437 -258 -113 C ATOM 1614 O GLY B 359 18.499 8.922 -20.689 1.00 19.63 O ANISOU 1614 O GLY B 359 2676 1982 2800 -330 -265 -142 O ATOM 1615 N TYR B 360 19.863 10.218 -19.445 1.00 19.73 N ANISOU 1615 N TYR B 360 2828 1801 2865 -508 -274 -174 N ATOM 1616 CA TYR B 360 19.483 9.673 -18.153 1.00 18.62 C ANISOU 1616 CA TYR B 360 2650 1681 2744 -445 -296 -271 C ATOM 1617 CB TYR B 360 20.482 10.115 -17.053 1.00 19.15 C ANISOU 1617 CB TYR B 360 2770 1677 2830 -579 -329 -331 C ATOM 1618 CG TYR B 360 19.942 9.873 -15.646 1.00 18.18 C ANISOU 1618 CG TYR B 360 2679 1534 2694 -499 -350 -425 C ATOM 1619 CD1 TYR B 360 19.945 8.585 -15.104 1.00 16.45 C ANISOU 1619 CD1 TYR B 360 2326 1457 2469 -465 -354 -465 C ATOM 1620 CE1 TYR B 360 19.438 8.342 -13.850 1.00 19.36 C ANISOU 1620 CE1 TYR B 360 2735 1814 2805 -398 -359 -536 C ATOM 1621 CZ TYR B 360 18.885 9.395 -13.126 1.00 19.45 C ANISOU 1621 CZ TYR B 360 2920 1679 2790 -350 -353 -585 C ATOM 1622 OH TYR B 360 18.382 9.138 -11.873 1.00 18.88 O ANISOU 1622 OH TYR B 360 2897 1608 2666 -282 -339 -658 O ATOM 1623 CE2 TYR B 360 18.840 10.677 -13.657 1.00 18.02 C ANISOU 1623 CE2 TYR B 360 2881 1343 2625 -365 -349 -557 C ATOM 1624 CD2 TYR B 360 19.353 10.902 -14.916 1.00 17.40 C ANISOU 1624 CD2 TYR B 360 2762 1269 2579 -442 -351 -469 C ATOM 1625 C TYR B 360 18.049 10.089 -17.759 1.00 19.14 C ANISOU 1625 C TYR B 360 2798 1672 2803 -267 -294 -288 C ATOM 1626 O TYR B 360 17.680 11.247 -17.870 1.00 21.05 O ANISOU 1626 O TYR B 360 3194 1761 3044 -218 -294 -255 O ATOM 1627 N GLU B 361 17.263 9.137 -17.275 1.00 18.20 N ANISOU 1627 N GLU B 361 2574 1657 2683 -169 -284 -337 N ATOM 1628 CA GLU B 361 15.899 9.416 -16.844 1.00 19.16 C ANISOU 1628 CA GLU B 361 2724 1749 2806 0 -265 -357 C ATOM 1629 CB GLU B 361 14.901 9.154 -17.981 1.00 18.69 C ANISOU 1629 CB GLU B 361 2575 1784 2741 107 -272 -291 C ATOM 1630 CG GLU B 361 14.816 10.226 -19.056 1.00 20.04 C ANISOU 1630 CG GLU B 361 2852 1865 2895 146 -296 -193 C ATOM 1631 CD GLU B 361 13.917 9.795 -20.203 1.00 22.31 C ANISOU 1631 CD GLU B 361 3033 2288 3154 236 -330 -129 C ATOM 1632 OE1 GLU B 361 14.066 8.623 -20.652 1.00 20.60 O ANISOU 1632 OE1 GLU B 361 2685 2224 2919 163 -336 -149 O ATOM 1633 OE2 GLU B 361 13.064 10.618 -20.659 1.00 23.98 O ANISOU 1633 OE2 GLU B 361 3300 2452 3359 383 -357 -61 O ATOM 1634 C GLU B 361 15.557 8.512 -15.689 1.00 17.64 C ANISOU 1634 C GLU B 361 2458 1633 261.

27. 240 -437 C ATOM 1635 O GLU B 361 15.996 7.369 -15.651 1.00 17.76 O ANISOU 1635 O GLU B 361 2363 1760 2626 -43 -244 -451 O ATOM 1636 N GLU B 362 14.776 9.020 -14.758 1.00 18.34 N ANISOU 1636 N GLU B 362 2620 1655 2692 137 -205 -484 N ATOM 1637 CA GLU B 362 14.217 8.208 -13.690 1.00 18.97 C ANISOU 1637 CA GLU B 362 2638 1816 2755 180 -158 -546 C ATOM 1638 CB GLU B 362 14.698 8.683 -12.317 1.00 18.78 C ANISOU 1638 CB GLU B 362 2764 1691 2682 150 -150 -626 C ATOM 1639 CG GLU B 362 14.269 7.780 -11.129 1.00 19.81 C ANISOU 1639 CG GLU B 362 2854 1908 2765 175 -96 -679 C ATOM 1640 CD GLU B 362 14.658 8.416 -9.769 1.00 23.89 C ANISOU 1640 CD GLU B 362 3556 2321 3202 160 -92 -765 C ATOM 1641 OE1 GLU B 362 15.700 8.061 -9.173 1.00 27.64 O ANISOU 1641 OE1 GLU B 362 4065 2806 3630.

38. 156 -790 O ATOM 1642 OE2 GLU B 362 13.946 9.338 -9.332 1.00 31.97 O ANISOU 1642 OE2 GLU B 362 4699 3247 4203 278 -32 -811 O ATOM 1643 C GLU B 362 12.692 8.261 -13.751 1.00 19.33 C ANISOU 1643 C GLU B 362 2608 1916 2818 350 -102 -537 C ATOM 1644 O GLU B 362 12.130 9.347 -13.924 1.00 21.05 O ANISOU 1644 O GLU B 362 2908 2040 3049 476 -89 -521 O ATOM 1645 N PHE B 363 12.053 7.096 -13.591 1.00 18.10 N ANISOU 1645 N PHE B 363 2298 1909 2669 352 -67 -544 N ATOM 1646 CA PHE B 363 10.603 6.935 -13.598 1.00 19.56 C ANISOU 1646 CA PHE B 363 2355 2196 2881 481 -536 C ATOM 1647 CB PHE B 363 10.160 6.097 -14.830 1.00 18.76 C ANISOU 1647 CB PHE B 363 2078 2239 2813 443 -60 -483 C ATOM 1648 CG PHE B 363 10.538 6.710 -16.149 1.00 20.16 C ANISOU 1648 CG PHE B 363 2290 2378 2990 445 -145 -419 C ATOM 1649 CD1 PHE B 363 9.671 7.585 -16.786 1.00 20.57 C ANISOU 1649 CD1 PHE B 363 2324 2434 3060 595 -170 -365 C ATOM 1650 CE1 PHE B 363 10.005 8.145 -17.991 1.00 22.34 C ANISOU 1650 CE1 PHE B 363 2603 2620 3264 598 -247 -290 C ATOM 1651 CZ PHE B 363 11.229 7.855 -18.587 1.00 17.85 C ANISOU 1651 CZ PHE B 363 2100 2021 2662 440 -280 -275 C ATOM 1652 CE2 PHE B 363 12.100 6.988 -17.975 1.00 18.88 C ANISOU 1652 CE2 PHE B 363 2224 2160 2789 301 -251 -336 C ATOM 1653 CD2 PHE B 363 11.761 6.407 -16.760 1.00 18.78 C ANISOU 1653 CD2 PHE B 363 2166 2175 2793 306 -193 -403 C ATOM 1654 C PHE B 363 10.104 6.182 -12.366 1.00 19.99 C ANISOU 1654 C PHE B 363 2365 2319 2910 48.

83. 588 C ATOM 1655 O PHE B 363 10.813 5.318 -11.820 1.00 19.21 O ANISOU 1655 O PHE B 363 2290 2232 2778 36.

82. 608 O ATOM 1656 N THR B 364 8.874 6.490 -11.950 1.00 21.40 N ANISOU 1656 N THR B 364 2475 2551 3103 622 169 -600 N ATOM 1657 CA THR B 364 8.094 5.540 -11.194 1.00 22.37 C ANISOU 1657 CA THR B 364 2478 2803 3219 605 268 -619 C ATOM 1658 CB THR B 364 7.228 6.189 -10.082 1.00 24.65 C ANISOU 1658 CB THR B 364 2799 3088 3478 761 405 -666 C ATOM 1659 OG1 THR B 364 6.244 7.069 -10.672 1.00 29.54 O ANISOU 1659 OG1 THR B 364 3325 3737 4161 950 417 -641 O ATOM 1660 CG2 THR B 364 8.077 6.917 -9.090 1.00 20.46 C ANISOU 1660 CG2 THR B 364 2522 2392 2860 769 420 -732 C ATOM 1661 C THR B 364 7.200 4.826 -12.190 1.00 23.57 C ANISOU 1661 C THR B 364 2398 3119 3440 586 242 -570 C ATOM 1662 O THR B 364 6.734 5.447 -13.162 1.00 24.92 O ANISOU 1662 O THR B 364 2497 3317 3654 681 180 -530 O ATOM 1663 N MSE B 365 6.990 3.527 -11.962 1.00 23.51 N ANISOU 1663 N MSE B 365 2289 3210 3433 455 278 -570 N ATOM 1664 CA MSE B 365 6.070 2.707 -12.758 1.00 25.28 C ANISOU 1664 CA MSE B 365 2293 3596 3716 395 258 -541 C ATOM 1665 CB MSE B 365 6.777 1.479 -13.354 1.00 23.17 C ANISOU 1665 CB MSE B 365 2037 3323 3443 205 188 -537 C ATOM 1666 CG MSE B 365 7.959 1.767 -14.260 1.00 23.72 C ANISOU 1666 CG MSE B 365 2224 3295 3494 18.

74. 527 C ATOM 1667 SE MSE B 365 9.006 0.180 -14.677 0.90 24.85 SE ANISOU 1667 SE MSE B 365 2418 3405 3619 -17.

33. 540 SE ATOM 1668 CE MSE B 365 7.640 -1.058 -15.246 1.00 20.54 C ANISOU 1668 CE MSE B 365 1672 3014 3117 -135.

41. 548 C ATOM 1669 C MSE B 365 4.961 2.217 -11.835 1.00 26.07 C ANISOU 1669 C MSE B 365 2259 3817 3829 397 400 -552 C ATOM 1670 O MSE B 365 5.252 1.610 -10.808 1.00 25.95 O ANISOU 1670 O MSE B 365 2332 3765 3763 319 488 -569 O ATOM 1671 N VAL B 366 3.699 2.486 -12.183 1.00 27.59 N ANISOU 1671 N VAL B 366 2234 4164 4084 489 424 -533 N ATOM 1672 CA VAL B 366 2.565 2.042 -11.348 1.00 29.18 C ANISOU 1672 CA VAL B 366 2265 4513 4308 484 578 -537 C ATOM 1673 CB VAL B 366 1.807 3.257 -10.708 1.00 31.18 C ANISOU 1673 CB VAL B 366 2482 4797 4568 737 692 -550 C ATOM 1674 CG1 VAL B 366 0.547 2.816 -9.890 1.00 31.65 C ANISOU 1674 CG1 VAL B 366 2322 5048 4655 741 877 -550 C ATOM 1675 CG2 VAL B 366 2.757 4.071 -9.830 1.00 29.76 C ANISOU 1675 CG2 VAL B 366 2601 4409 4296 827 734 -597 C ATOM 1676 C VAL B 366 1.630 1.113 -12.138 1.00 30.40 C ANISOU 1676 C VAL B 366 2151 4861 4538 349 536 -511 C ATOM 1677 O VAL B 366 1.042 1.529 -13.138 1.00 31.27 O ANISOU 1677 O VAL B 366 2097 5082 4703 424 432 -486 O ATOM 1678 N GLY B 367 1.533 -0.147 -11.709 1.00 30.76 N ANISOU 1678 N GLY B 367 2170 4939 4578 139 604 -513 N ATOM 1679 CA GLY B 367 0.588 -1.110 -12.303 1.00 32.91 C ANISOU 1679 CA GLY B 367 2196 5388 4921 -34 581 -500 C ATOM 1680 C GLY B 367 -0.498 -1.517 -11.325 1.00 35.94 C ANISOU 1680 C GLY B 367 2401 5920 5333 -85 771 -488 C ATOM 1681 O GLY B 367 -0.558 -0.986 -10.220 1.00 37.15 O ANISOU 1681 O GLY B 367 2625 6048 5442 44 925 -491 O ATOM 1682 N LYS B 368 -1.356 -2.458 -11.722 1.00 37.73 N ANISOU 1682 N LYS B 368 2403 6306 5626 -285 766 -478 N ATOM 1683 CA LYS B 368 -2.392 -2.977 -10.842 1.00 40.82 C ANISOU 1683 CA LYS B 368 2606 6852 6051 -385 959 -457 C ATOM 1684 CB LYS B 368 -3.379 -3.863 -11.614 1.00 43.14 C ANISOU 1684 CB LYS B 368 2608 7343 6439 -618 896 -451 C ATOM 1685 CG LYS B 368 -4.224 -3.164 -12.650 1.00 46.39 C ANISOU 1685 CG LYS B 368 2718 7976 6933 -496 753 -448 C ATOM 1686 CD LYS B 368 -5.098 -4.196 -13.325 1.00 53.87 C ANISOU 1686 CD LYS B 368 3403 9110 7957 -784 679 -454 C ATOM 1687 CE LYS B 368 -5.442 -3.835 -14.770 1.00 56.62 C ANISOU 1687 CE LYS B 368 3572 9602 8340 -740 427 -464 C ATOM 1688 NZ LYS B 368 -6.644 -4.642 -15.228 1.00 62.56 N ANISOU 1688 NZ LYS B 368 3968 10621 9180 -997 377 -470 N ATOM 1689 C LYS B 368 -1.811 -3.784 -9.679 1.00 40.22 C ANISOU 1689 C LYS B 368 2770 6621 5891 -521 1112 -444 C ATOM 1690 O LYS B 368 -2.325 -3.708 -8.559 1.00 41.54 O ANISOU 1690 O LYS B 368 2901 6854 6028 -488 1318 -424 O ATOM 1691 N ARG B 369 -0.739 -4.539 -9.950 1.00 38.40 N ANISOU 1691 N ARG B 369 2787 6190 5615 -656 1015 -452 N ATOM 1692 CA ARG B 369 -0.231 -5.556 -9.020 1.00 38.59 C ANISOU 1692 CA ARG B 369 3028 6068 5567 -815 1127 -423 C ATOM 1693 CB ARG B 369 -0.483 -6.952 -9.606 1.00 39.39 C ANISOU 1693 CB ARG B 369 3090 6155 5723 -1113 1085 -417 C ATOM 1694 CG ARG B 369 -1.889 -7.506 -9.367 1.00 43.61 C ANISOU 1694 CG ARG B 369 3344 6893 6331 -1301 1219 -390 C ATOM 1695 CD ARG B 369 -2.166 -8.798 -10.162 1.00 45.50 C ANISOU 1695 CD ARG B 369 3542 7112 6635 -1617 1138 -405 C ATOM 1696 NE ARG B 369 -2.734 -8.513 -11.485 1.00 50.50 N ANISOU 1696 NE ARG B 369 3925 7913 7351 -1634 956 -457 N ATOM 1697 CZ ARG B 369 -2.076 -8.625 -12.642 1.00 51.55 C ANISOU 1697 CZ ARG B 369 4162 7949 7474 -1642 750 -512 C ATOM 1698 NH1 ARG B 369 -0.809 -9.053 -12.673 1.00 49.87 N ANISOU 1698 NH1 ARG B 369 4281 7475 7191 -1634 707 -525 N ATOM 1699 NH2 ARG B 369 -2.696 -8.327 -13.783 1.00 52.31 N ANISOU 1699 NH2 ARG B 369 4025 8226 7624 -1654 588 -550 N ATOM 1700 C ARG B 369 1.251 -5.377 -8.622 1.00 35.98 C ANISOU 1700 C ARG B 369 3036 5502 5132 -717 1074 -428 C ATOM 1701 O ARG B 369 1.835 -6.216 -7.915 1.00 36.25 O ANISOU 1701 O ARG B 369 3277 5399 5097 -821 1132 -395 O ATOM 1702 N ALA B 370 1.852 -4.282 -9.083 1.00 33.63 N ANISOU 1702 N ALA B 370 2790 5164 4825 -519 958 -462 N ATOM 1703 CA ALA B 370 3.242 -3.951 -8.791 1.00 31.07 C ANISOU 1703 CA ALA B 370 2741 4650 4415 -426 890 -472 C ATOM 1704 CB ALA B 370 4.209 -4.861 -9.590 1.00 29.47 C ANISOU 1704 CB ALA B 370 2663 4314 4222 -553 754 -475 C ATOM 1705 C ALA B 370 3.536 -2.485 -9.087 1.00 30.13 C ANISOU 1705 C ALA B 370 2633 4522 4291 -205 816 -506 C ATOM 1706 O ALA B 370 2.837 -1.834 -9.869 1.00 30.45 O ANISOU 1706 O ALA B 370 2489 4676 4403 -120 767 -516 O ATOM 1707 N THR B 371 4.577 -1.968 -8.447 1.00 29.21 N ANISOU 1707 N THR B 371 2743 4267 4088 -115 802 -520 N ATOM 1708 CA THR B 371 5.070 -0.623 -8.712 1.00 28.42 C ANISOU 1708 CA THR B 371 2713 4108 3978 60 723 -553 C ATOM 1709 CB THR B 371 4.594 0.442 -7.657 1.00 29.87 C ANISOU 1709 CB THR B 371 2940 4307 4103 233 854 -584 C ATOM 1710 OG1 THR B 371 5.182 0.139 -6.396 1.00 31.90 O ANISOU 1710 OG1 THR B 371 3400 4485 4238 197 929 -590 O ATOM 1711 CG2 THR B 371 3.077 0.486 -7.506 1.00 29.41 C ANISOU 1711 CG2 THR B 371 2640 4434 4101 284 995 -575 C ATOM 1712 C THR B 371 6.587 -0.709 -8.730 1.00 26.74 C ANISOU 1712 C THR B 371 2715 3734 3710 26 611 -559 C ATOM 1713 O THR B 371 7.167 -1.696 -8.278 1.00 27.73 O ANISOU 1713 O THR B 371 2942 3802 3791 -84 618 -537 O ATOM 1714 N ALA B 372 7.245 0.306 -9.262 1.00 24.71 N ANISOU 1714 N ALA B 372 2524 3405 3458 120 509 -581 N ATOM 1715 CA ALA B 372 8.691 0.260 -9.366 1.00 22.74 C ANISOU 1715 CA ALA B 372 2435 3033 3172 78 402 -584 C ATOM 1716 CB ALA B 372 9.123 -0.612 -10.575 1.00 20.88 C ANISOU 1716 CB ALA B 372 2138 2802 2995 -29 305 -563 C ATOM 1717 C ALA B 372 9.313 1.651 -9.455 1.00 21.47 C ANISOU 1717 C ALA B 372 2381 2784 2993 183 338 -614 C ATOM 1718 O ALA B 372 8.644 2.637 -9.767 1.00 22.51 O ANISOU 1718 O ALA B 372 2465 2931 3157 299 353 -625 O ATOM 1719 N ILE B 373 10.596 1.712 -9.160 1.00 20.23 N ANISOU 1719 N ILE B 373 2368 2532 2787 140 265 -623 N ATOM 1720 CA ILE B 373 11.406 2.858 -9.509 1.00 20.10 C ANISOU 1720 CA ILE B 373 2445 2422 2770 176 179 -644 C ATOM 1721 CB ILE B 373 12.105 3.494 -8.281 1.00 20.66 C ANISOU 1721 CB ILE B 373 2702 2404 2743 188 175 -692 C ATOM 1722 CG1 ILE B 373 11.114 3.705 -7.131 1.00 21.48 C ANISOU 1722 CG1 ILE B 373 2853 2532 2776 274 308 -730 C ATOM 1723 CD1 ILE B 373 11.724 4.339 -5.870 1.00 23.57 C ANISOU 1723 CD1 ILE B 373 3331 2712 2913 284 306 -794 C ATOM 1724 CG2 ILE B 373 12.777 4.814 -8.687 1.00 20.73 C ANISOU 1724 CG2 ILE B 373 2810 2302 2764 20.

96. 719 C ATOM 1725 C ILE B 373 12.440 2.357 -10.494 1.00 18.98 C

ANISOU 1725 C ILE B 373 2275 2270 2668 84 75 -613 C

ATOM 1726 O ILE B 373 13.084 1.346 -10.229 1.00 18.45 O

ANISOU 1726 O ILE B 373 2219 2210 2582 9 57 -599 O

ATOM 1727 N LEU B 374 12.551 3.049 -11.633 1.00 19.11 N

ANISOU 1727 N LEU B 374 2259 2268 2733 102 18 -597 N

ATOM 1728 CA LEU B 374 13.487 2.723 -12.716 1.00 17.96 C

ANISOU 1728 CA LEU B 374 2084 2123 2617 26 -60 -569 C

ATOM 1729 CB LEU B 374 12.712 2.403 -14.002 1.00 17.80 C

ANISOU 1729 CB LEU B 374 1942 2182 2641 33 -70 -541 C

ATOM 1730 CG LEU B 374 13.468 2.237 -15.313 1.00 17.37 C

ANISOU 1730 CG LEU B 374 1867 2137 2597 -24 -132 -516 C

ATOM 1731 CD1 LEU B 374 14.387 1.025 -15.269 1.00 16.31 C

ANISOU 1731 CD1 LEU B 374 1730 2011 2458 -107 -135 -527 C

ATOM 1732 CD2 LEU B 374 12.488 2.104 -16.488 1.00 19.06 C

ANISOU 1732 CD2 LEU B 374 1980 2438 2824 -4 -153 -495 C

ATOM 1733 C LEU B 374 14.409 3.901 -12.991 1.00 18.14 C

ANISOU 1733 C LEU B 374 2200 2055 2636 17 -119 -567 C

ATOM 1734 O LEU B 374 13.919 5.035 -13.178 1.00 17.76 O

ANISOU 1734 O LEU B 374 2202 1951 2595 91 -114 -565 O

ATOM 1735 N ARG B 375 15.721 3.625 -12.989 1.00 16.95 N

ANISOU 1735 N ARG B 375 2072 1891 2478 -71 -171 -564 N

ATOM 1736 CA ARG B 375 16.705 4.489 -13.602 1.00 17.47 C

ANISOU 1736 CA ARG B 375 2179 1903 2558 -127 -225 -546 C

ATOM 1737 CB ARG B 375 17.892 4.764 -12.677 1.00 18.12 C

ANISOU 1737 CB ARG B 375 2329 1943 2611 -204 -277 -574 C

ATOM 1738 CG ARG B 375 17.604 5.831 -11.648 1.00 18.30 C

ANISOU 1738 CG ARG B 375 2500 1865 2590 -178 -276 -625 C

ATOM 1739 CD ARG B 375 18.705 5.872 -10.626 1.00 17.52 C

ANISOU 1739 CD ARG B 375 2459 1755 2442 -267 -347 -663 C

ATOM 1740 NE ARG B 375 18.396 6.839 -9.574 1.00 20.93 N

ANISOU 1740 NE ARG B 375 3063 2084 2807 -248 -345 -733 N

ATOM 1741 CZ ARG B 375 18.996 6.901 -8.392 1.00 22.13 C

ANISOU 1741 CZ ARG B 375 3304 2227 2876 -303 -404 -787 C

ATOM 1742 NH1 ARG B 375 19.955 6.037 -8.075 1.00 23.45 N

ANISOU 1742 NH1 ARG B 375 3389 2494 3028 -370 -480 -765 N

ATOM 1743 NH2 ARG B 375 18.629 7.827 -7.528 1.00 24.29 N

ANISOU 1743 NH2 ARG B 375 3760 2394 3076 -279 -390 -865 N

ATOM 1744 C ARG B 375 17.209 3.921 -14.913 1.00 17.41 C

ANISOU 1744 C ARG B 375 2079 1958 2578 -175 -238 -505 C

ATOM 1745 O ARG B 375 17.554 2.747 -15.016 1.00 17.68 O

ANISOU 1745 O ARG B 375 2043 2057 2618 -198 -232 -507 O

ATOM 1746 N LYS B 376 17.327 4.788 -15.899 1.00 17.92 N

ANISOU 1746 N LYS B 376 2167 1990 2651 -187 -251 -466 N

ATOM 1747 CA LYS B 376 17.635 4.368 -17.233 1.00 18.44 C

ANISOU 1747 CA LYS B 376 2166 2121 2718 -219 -249 -427 C

ATOM 1748 CB LYS B 376 16.313 4.249 -17.956 1.00 19.30 C

ANISOU 1748 CB LYS B 376 2242 2274 2816 -141 -242 -411 C

ATOM 1749 CG LYS B 376 16.410 4.111 -19.385 1.00 24.35 C

ANISOU 1749 CG LYS B 376 2854 2971 3426 -163 -251 -371 C

ATOM 1750 CD LYS B 376 15.233 4.725 -20.053 1.00 25.52 C

ANISOU 1750 CD LYS B 376 3010 3132 3554 -79 -279 -330 C

ATOM 1751 CE LYS B 376 15.262 4.220 -21.479 1.00 24.91 C

ANISOU 1751 CE LYS B 376 2899 3145 3419 -111 -296 -304 C

ATOM 1752 NZ LYS B 376 16.403 4.826 -22.153 1.00 24.23 N

ANISOU 1752 NZ LYS B 376 2885 3021 3302 -176 -279 -252 N

ATOM 1753 C LYS B 376 18.551 5.421 -17.892 1.00 18.68 C

ANISOU 1753 C LYS B 376 2253 2098 2746 -293 -262 -380 C

ATOM 1754 O LYS B 376 18.550 6.582 -17.503 1.00 19.26 O

ANISOU 1754 O LYS B 376 2432 2063 2823 -300 -277 -372 O

ATOM 1755 N ALA B 377 19.344 5.004 -18.873 1.00 18.41 N

ANISOU 1755 N ALA B 377 2158 2132 2704 -354 -244 -351 N

ATOM 1756 CA ALA B 377 20.187 5.927 -19.633 1.00 19.30 C

ANISOU 1756 CA ALA B 377 2313 2213 2809 -443 -234 -292 C

ATOM 1757 CB ALA B 377 21.642 5.877 -19.139 1.00 18.88 C

ANISOU 1757 CB ALA B 377 2200 2184 2791 -557 -236 -304 C

ATOM 1758 C ALA B 377 20.043 5.447 -21.070 1.00 19.24 C

ANISOU 1758 C ALA B 377 2269 2292 2751 -429 -199 -253 C

ATOM 1759 O ALA B 377 19.145 4.641 -21.328 1.00 18.97 O

ANISOU 1759 O ALA B 377 2199 2314 2694 -354 -205 -280 O

ATOM 1760 N THR B 378 20.885 5.930 -21.991 1.00 19.58 N

ANISOU 1760 N THR B 378 2326 2348 2766 -514 -160 -192 N

ATOM 1761 CA THR B 378 20.812 5.546 -23.409 1.00 19.32 C

ANISOU 1761 CA THR B 378 2285 2401 2653 -506 -118 -155 C

ATOM 1762 CB THR B 378 21.861 6.284 -24.233 1.00 20.34 C

ANISOU 1762 CB THR B 378 2444 2534 2751 -620 -56 -76 C

ATOM 1763 OG1 THR B 378 21.768 7.684 -23.973 1.00 20.74 O

ANISOU 1763 OG1 THR B 378 2618 2442 2819 -665 -85 -11 O

ATOM 1764 CG2 THR B 378 21.664 6.025 -25.717 1.00 20.00 C

ANISOU 1764 CG2 THR B 378 2433 2574 2591 -603 -11 -31 C

ATOM 1765 C THR B 378 21.001 4.033 -23.613 1.00 19.30 C

ANISOU 1765 C THR B 378 2178 2513 2641 -474 -84 -227 C

ATOM 1766 O THR B 378 22.120 3.502 -23.476 1.00 19.32 O

ANISOU 1766 O THR B 378 2096 2570 2676 -516 -33 -250 O

ATOM 1767 N ARG B 379 19.914 3.359 -23.968 1.00 18.79 N

ANISOU 1767 N ARG B 379 2122 2483 2535 -401 -113 -261 N

ATOM 1768 CA ARG B 379 19.921 1.918 -24.208 1.00 19.22 C

ANISOU 1768 CA ARG B 379 2121 2610 2572 -377 -84 -338 C

ATOM 1769 CB ARG B 379 20.587 1.584 -25.568 1.00 20.01 C

ANISOU 1769 CB ARG B 379 2232 2791 2579 -405 -331 C

ATOM 1770 CG ARG B 379 19.959 2.282 -26.762 1.00 21.05 C

ANISOU 1770 CG ARG B 379 2454 2950 2595 -411 -34 -267 C

ATOM 1771 CD ARG B 379 20.376 1.641 -28.060 1.00 20.86 C

ANISOU 1771 CD ARG B 379 2459 3018 2448 -427.

38. 291 C

ATOM 1772 NE ARG B 379 19.805 0.291 -28.188 1.00 21.07 N

ANISOU 1772 NE ARG B 379 2478 3077 2449 -392.

21. 402 N

ATOM 1773 CZ ARG B 379 20.169 -0.608 -29.110 1.00 21.75 C

ANISOU 1773 CZ ARG B 379 2601 3225 2438 -392.

91. 469 C

ATOM 1774 NH1 ARG B 379 21.092 -0.337 -30.021 1.00 20.29 N

ANISOU 1774 NH1 ARG B 379 2446 3100 2163 -415 195 -434 N

ATOM 1775 NH2 ARG B 379 19.594 -1.797 -29.126 1.00 22.67 N

ANISOU 1775 NH2 ARG B 379 2735 3336 2542 -377.

67. 576 N

ATOM 1776 C ARG B 379 20.589 1.159 -23.045 1.00 19.24 C

ANISOU 1776 C ARG B 379 2052 2596 2663 -368 -69 -390 C

ATOM 1777 O ARG B 379 21.432 0.291 -23.257 1.00 18.60 O

ANISOU 1777 O ARG B 379 1921 2560 2586 -362 -11 -424 O

ATOM 1778 N ARG B 380 20.187 1.503 -21.816 1.00 20.13 N

ANISOU 1778 N ARG B 380 2170 2643 2835 -353 -120 -395 N

ATOM 1779 CA ARG B 380 20.790 0.946 -20.598 1.00 20.31 C

ANISOU 1779 CA ARG B 380 2146 2650 2921 -343 -125 -427 C

ATOM 1780 CB ARG B 380 22.100 1.697 -20.262 1.00 21.34 C

ANISOU 1780 CB ARG B 380 2237 2785 3086 -409 -126 -393 C

ATOM 1781 CG ARG B 380 22.872 1.156 -19.087 1.00 24.13 C

ANISOU 1781 CG ARG B 380 2528 3150 3490 -396 -155 -417 C

ATOM 1782 CD ARG B 380 24.060 2.071 -18.796 1.00 33.52 C

ANISOU 1782 CD ARG B 380 3664 4360 4713 -492 -179 -385 C

ATOM 1783 NE ARG B 380 24.427 2.050 -17.376 1.00 40.26 N

ANISOU 1783 NE ARG B 380 4504 5201 5593 -496 -257 -405 N

ATOM 1784 CZ ARG B 380 25.066 3.030 -16.744 1.00 41.26 C

ANISOU 1784 CZ ARG B 380 4631 5311 5736 -597 -318 -398 C

ATOM 1785 NH1 ARG B 380 25.427 4.118 -17.419 1.00 44.00 N

ANISOU 1785 NH1 ARG B 380 4992 5636 6088 -711 -298 -363 N

ATOM 1786 NH2 ARG B 380 25.345 2.919 -15.441 1.00 40.13 N

ANISOU 1786 NH2 ARG B 380 4489 5166 5591 -596 -403 -425 N

ATOM 1787 C ARG B 380 19.822 1.058 -19.448 1.00 18.92 C

ANISOU 1787 C ARG B 380 2007 2415 2767 -309 -171 -445 C

ATOM 1788 O ARG B 380 19.320 2.129 -19.164 1.00 19.53 O

ANISOU 1788 O ARG B 380 2136 2442 2844 -309 -199 -423 O

ATOM 1789 N LEU B 381 19.535 -0.060 -18.802 1.00 19.03 N

ANISOU 1789 N LEU B 381 2006 2427 2796 -274 -165 -485 N

ATOM 1790 CA LEU B 381 18.844 -0.036 -17.509 1.00 18.96 C

ANISOU 1790 CA LEU B 381 2029 2373 2800 -249 -186 -498 C

ATOM 1791 CB LEU B 381 18.117 -1.356 -17.258 1.00 18.22 C

ANISOU 1791 CB LEU B 381 1933 2281 2708 -229 -160 -529 C

ATOM 1792 CG LEU B 381 17.277 -1.567 -16.000 1.00 18.70 C

ANISOU 1792 CG LEU B 381 2025 2311 2770 -212 -152 -535 C

ATOM 1793 CD1 LEU B 381 16.073 -2.493 -16.303 1.00 16.19 C

ANISOU 1793 CD1 LEU B 381 1688 2009 2454 -232 -118 -558 C

ATOM 1794 CD2 LEU B 381 18.121 -2.129 -14.860 1.00 18.01 C

ANISOU 1794 CD2 LEU B 381 1969 2193 2680 -196 -161 -527 C

ATOM 1795 C LEU B 381 19.942 0.175 -16.476 1.00 18.78 C

ANISOU 1795 C LEU B 381 2006 2334 2794 -262 -216 -491 C

ATOM 1796 O LEU B 381 20.876 -0.627 -16.374 1.00 18.28 O

ANISOU 1796 O LEU B 381 1898 2301 2747 -252 -214 -491 O

ATOM 1797 N VAL B 382 19.839 1.265 -15.730 1.00 19.29 N

ANISOU 1797 N VAL B 382 2125 2353 2851 -279 -250 -489 N

ATOM 1798 CA VAL B 382 20.836 1.563 -14.675 1.00 19.54 C

ANISOU 1798 CA VAL B 382 2167 2377 2881 -314 -304 -493 C

ATOM 1799 CB VAL B 382 20.934 3.093 -14.380 1.00 20.23 C

ANISOU 1799 CB VAL B 382 2332 2395 2958 -372 -341 -498 C

ATOM 1800 CG1 VAL B 382 21.928 3.397 -13.238 1.00 19.44 C

ANISOU 1800 CG1 VAL B 382 2249 2295 2842 -433 -418 -518 C

ATOM 1801 CG2 VAL B 382 21.319 3.844 -15.652 1.00 20.85 C

ANISOU 1801 CG2 VAL B 382 2392 2472 3060 -431 -323 -459 C

ATOM 1802 C VAL B 382 20.465 0.761 -13.431 1.00 19.16 C

ANISOU 1802 C VAL B 382 2157 2320 2803 -264 -312 -511 C

ATOM 1803 O VAL B 382 21.273 0.005 -12.911 1.00 20.08 O

ANISOU 1803 O VAL B 382 2241 2469 2918 -251 -343 -500 O

ATOM 1804 N GLN B 383 19.221 0.890 -12.992 1.00 18.96 N

ANISOU 1804 N GLN B 383 2195 2258 2752 -228 -275 -528 N

ATOM 1805 CA GLN B 383 18.755 0.178 -11.818 1.00 19.44 C

ANISOU 1805 CA GLN B 383 2306 2311 2769 -193 -258 -534 C

ATOM 1806 CB GLN B 383 19.339 0.796 -10.539 1.00 20.96 C

ANISOU 1806 CB GLN B 383 2581 2483 2901 -208 -319 -552 C

ATOM 1807 CG GLN B 383 18.988 0.003 -9.318 1.00 28.70 C

ANISOU 1807 CG GLN B 383 3630 3464 3810 -172 -301 -545 C

ATOM 1808 CD GLN B 383 19.917 0.256 -8.142 1.00 38.33 C

ANISOU 1808 CD GLN B 383 4920 4691 4951 -190 -395 -552 C

ATOM 1809 OE1 GLN B 383 20.549 1.348 -8.009 1.00 37.76 O

ANISOU 1809 OE1 GLN B 383 4873 4607 4867 -246 -467 -588 O

ATOM 1810 NE2 GLN B 383 20.021 -0.768 -7.272 1.00 39.52 N

ANISOU 1810 NE2 GLN B 383 5116 4861 5041 -153 -403 -515 N

ATOM 1811 C GLN B 383 17.247 0.146 -11.767 1.00 17.86 C

ANISOU 1811 C GLN B 383 2121 2104 2562 -158 -184 -546 C

ATOM 1812 O GLN B 383 16.598 1.075 -12.243 1.00 16.03 O

ANISOU 1812 O GLN B 383 1886 1860 2344 -140 -169 -556 O

ATOM 1813 N LEU B 384 16.709 -0.958 -11.236 1.00 17.13 N

ANISOU 1813 N LEU B 384 2036 2020 2452 -149 -135 -536 N

ATOM 1814 CA LEU B 384 15.291 -1.124 -11.035 1.00 17.71 C

ANISOU 1814 CA LEU B 384 2096 2111 2521 -135 -54 -542 C

ATOM 1815 CB LEU B 384 14.719 -2.032 -12.141 1.00 17.64 C

ANISOU 1815 CB LEU B 384 2001 2134 2568 -172 -28 -537 C

ATOM 1816 CG LEU B 384 13.218 -2.392 -12.135 1.00 17.32 C

ANISOU 1816 CG LEU B 384 1897 2141 2542 -192.

47. 541 C

ATOM 1817 CD1 LEU B 384 12.346 -1.239 -12.603 1.00 13.70 C

ANISOU 1817 CD1 LEU B 384 1367 1735 2105 -139.

48. 553 C

ATOM 1818 CD2 LEU B 384 12.974 -3.626 -12.969 1.00 18.57 C

ANISOU 1818 CD2 LEU B 384 2013 2307 2737 -267.

54. 544 C

ATOM 1819 C LEU B 384 14.984 -1.751 -9.669 1.00 18.33 C

ANISOU 1819 C LEU B 384 2251 2179 2533 -132 -1 -529 C

ATOM 1820 O LEU B 384 15.530 -2.822 -9.331 1.00 18.89 O

ANISOU 1820 O LEU B 384 2361 2229 2587 -149 -12 -496 O

ATOM 1821 N ILE B 385 14.075 -1.135 -8.921 1.00 18.21 N

ANISOU 1821 N ILE B 385 2267 2178 2475 -99.

66. 548 N ATOM 1822 CA ILE B 385 13.525 -1.725 -7.689 1.00 19.18 C ANISOU 1822 CA ILE B 385 2460 2308 2520 -101 151 -530 C ATOM 1823 CB ILE B 385 13.787 -0.844 -6.427 1.00 20.69 C ANISOU 1823 CB ILE B 385 2787 2478 2597 -54 150 -561 C ATOM 1824 CG1 ILE B 385 15.258 -0.466 -6.346 1.00 21.44 C ANISOU 1824 CG1 ILE B 385 2946 2535 2668 -67.

10. 570 C ATOM 1825 CD1 ILE B 385 15.488 0.659 -5.362 1.00 26.55 C ANISOU 1825 CD1 ILE B 385 3726 3152 3211 -43 -628 C ATOM 1826 CG2 ILE B 385 13.366 -1.580 -5.128 1.00 19.88 C ANISOU 1826 CG2 ILE B 385 2782 2389 2383 -62 240 -529 C ATOM 1827 C ILE B 385 12.005 -1.915 -7.850 1.00 19.64 C ANISOU 1827 C ILE B 385 2419 2430 2616 -108 271 -529 C ATOM 1828 O ILE B 385 11.281 -0.951 -8.157 1.00 18.63 O ANISOU 1828 O ILE B 385 2224 2339 2517 -49 299 -561 O ATOM 1829 N VAL B 386 11.540 -3.146 -7.645 1.00 20.36 N ANISOU 1829 N VAL B 386 2497 2531 2708 -181 338 -489 N ATOM 1830 CA VAL B 386 10.150 -3.524 -7.836 1.00 21.66 C ANISOU 1830 CA VAL B 386 2538 2772 2919 -229 446 -483 C ATOM 1831 CB VAL B 386 9.994 -4.733 -8.805 1.00 21.60 C ANISOU 1831 CB VAL B 386 2463 2755 2991 -344 426 -466 C ATOM 1832 CG1 VAL B 386 8.493 -5.016 -9.111 1.00 20.69 C ANISOU 1832 CG1 VAL B 386 2180 2746 2934 -422 516 -468 C ATOM 1833 CG2 VAL B 386 10.748 -4.499 -10.055 1.00 20.40 C ANISOU 1833 CG2 VAL B 386 2279 2580 2894 -326 304 -494 C ATOM 1834 C VAL B 386 9.522 -3.950 -6.522 1.00 24.28 C ANISOU 1834 C VAL B 386 2935 3125 3166 -253 584 -450 C ATOM 1835 O VAL B 386 10.124 -4.709 -5.755 1.00 24.69 O ANISOU 1835 O VAL B 386 3130 3109 3141 -286 588 -403 O ATOM 1836 N SER B 387 8.292 -3.476 -6.306 1.00 26.04 N ANISOU 1836 N SER B 387 3043 3448 3401 -229 700 -466 N ATOM 1837 CA SER B 387 7.460 -3.856 -5.191 1.00 28.34 C ANISOU 1837 CA SER B 387 3353 3793 3620 -262 868 -434 C ATOM 1838 CB SER B 387 7.142 -2.619 -4.362 1.00 28.84 C ANISOU 1838 CB SER B 387 3457 3899 3602 -119 947 -482 C ATOM 1839 OG SER B 387 6.509 -2.975 -3.165 1.00 32.36 O ANISOU 1839 OG SER B 387 3957 4394 3942 -143 1122 -451 O ATOM 1840 C SER B 387 6.204 -4.454 -5.815 1.00 30.08 C ANISOU 1840 C SER B 387 3358 4122 3947 -367 949 -418 C ATOM 1841 O SER B 387 5.597 -3.846 -6.691 1.00 30.62 O ANISOU 1841 O SER B 387 3245 4280 4109 -323 915 -454 O ATOM 1842 N GLY B 388 5.827 -5.658 -5.406 1.00 31.67 N ANISOU 1842 N GLY B 388 3582 4316 4136 -517 1043 -359 N ATOM 1843 CA GLY B 388 4.716 -6.338 -6.053 1.00 33.63 C ANISOU 1843 CA GLY B 388 3625 4660 4491 -666 1099 -348 C ATOM 1844 C GLY B 388 3.996 -7.304 -5.157 1.00 36.39 C ANISOU 1844 C GLY B 388 3994 5032 4800 -818 1277 -279 C ATOM 1845 O GLY B 388 4.534 -7.712 -4.131 1.00 36.83 O ANISOU 1845 O GLY B 388 4267 4991 4736 -821 1336 -224 O ATOM 1846 N LYS B 389 2.775 -7.660 -5.557 1.00 39.31 N ANISOU 1846 N LYS B 389 4131 5538 5266 -952 1358 -276 N ATOM 1847 CA LYS B 389 1.905 -8.546 -4.799 1.00 42.59 C ANISOU 1847 CA LYS B 389 4517 6004 5664 -1134 1549 -207 C ATOM 1848 CB LYS B 389 0.455 -8.392 -5.270 1.00 45.19 C ANISOU 1848 CB LYS B 389 4495 6563 6111 -1219 1629 -227 C ATOM 1849 CG LYS B 389 -0.202 -7.040 -4.873 1.00 47.63 C ANISOU 1849 CG LYS B 389 4629 7059 6410 -998 1722 -262 C ATOM 1850 CD LYS B 389 -1.671 -6.960 -5.309 1.00 49.06 C ANISOU 1850 CD LYS B 389 4426 7496 6718 -1071 1803 -268 C ATOM 1851 CE LYS B 389 -2.366 -5.751 -4.683 1.00 52.41 C ANISOU 1851 CE LYS B 389 4699 8096 7120 -834 1950 -290 C ATOM 1852 NZ LYS B 389 -3.530 -5.319 -5.518 1.00 55.24 N ANISOU 1852 NZ LYS B 389 4659 8702 7629 -803 1926 -313 N ATOM 1853 C LYS B 389 2.346 -10.017 -4.832 1.00 42.90 C ANISOU 1853 C LYS B 389 4742 5859 5697 -1341 1534 -147 C ATOM 1854 O LYS B 389 2.093 -10.748 -3.870 1.00 44.63 O ANISOU 1854 O LYS B 389 5079 6036 5842 -1458 1691 -62 O ATOM 1855 N ASP B 390 3.002 -10.448 -5.926 1.00 41.86 N ANISOU 1855 N ASP B 390 4658 5610 5637 -1378 1356 -187 N ATOM 1856 CA ASP B 390 3.552 -11.836 -6.076 1.00 42.33 C ANISOU 1856 CA ASP B 390 4930 5455 5698 -1538 1326 -145 C ATOM 1857 CB ASP B 390 2.436 -12.859 -6.342 1.00 44.76 C ANISOU 1857 CB ASP B 390 5124 5793 6090 -1829 1420 -127 C ATOM 1858 CG ASP B 390 1.592 -12.508 -7.561 1.00 44.57 C ANISOU 1858 CG ASP B 390 4794 5948 6194 -1903 1333 -218 C ATOM 1859 OD1 ASP B 390 2.129 -11.946 -8.525 1.00 43.20 O ANISOU 1859 OD1 ASP B 390 4586 5778 6050 -1774 1162 -293 O ATOM 1860 OD2 ASP B 390 0.384 -12.797 -7.556 1.00 46.53 O ANISOU 1860 OD2 ASP B 390 4828 6344 6507 -2095 1432 -208 O ATOM 1861 C ASP B 390 4.666 -11.971 -7.140 1.00 40.43 C ANISOU 1861 C ASP B 390 4791 5075 5495 -1464 1126 -205 C ATOM 1862 O ASP B 390 4.998 -10.988 -7.788 1.00 39.18 O ANISOU 1862 O ASP B 390 4534 4994 5360 -1312 1011 -272 O ATOM 1863 N GLU B 391 5.221 -13.178 -7.325 1.00 40.63 N ANISOU 1863 N GLU B 391 5020 4893 5525 -1566 1099 -179 N ATOM 1864 CA GLU B 391 6.313 -13.425 -8.304 1.00 39.14 C ANISOU 1864 CA GLU B 391 4939 4566 5365 -1487 939 -236 C ATOM 1865 CB GLU B 391 6.913 -14.847 -8.174 1.00 40.09 C ANISOU 1865 CB GLU B 391 5332 4428 5474 -1569 953 -186 C ATOM 1866 CG GLU B 391 8.099 -14.930 -7.176 1.00 40.49 C ANISOU 1866 CG GLU B 391 5615 4348 5420 -1384 945 -95 C ATOM 1867 CD GLU B 391 8.475 -16.353 -6.733 1.00 43.04 C ANISOU 1867 CD GLU B 391 6221 4416 5717 -1454 995 -5 C ATOM 1868 OE1 GLU B 391 8.222 -17.326 -7.492 1.00 45.74 O ANISOU 1868 OE1 GLU B 391 6626 4619 6135 -1610 998 -44 O ATOM 1869 OE2 GLU B 391 9.052 -16.495 -5.615 1.00 44.91 O ANISOU 1869 OE2 GLU B 391 6636 4581 5848 -1347 1025 106 O ATOM 1870 C GLU B 391 5.964 -13.106 -9.762 1.00 38.03 C ANISOU 1870 C GLU B 391 4609 4525 5316 -1529 824 -347 C ATOM 1871 O GLU B 391 6.794 -12.544 -10.477 1.00 36.08 O ANISOU 1871 O GLU B 391 4365 4273 5069 -1380 701 -400 O ATOM 1872 N GLN B 392 4.750 -13.463 -10.192 1.00 39.60 N ANISOU 1872 N GLN B 392 4640 4822 5583 -1740 863 -375 N ATOM 1873 CA GLN B 392 4.252 -13.121 -11.535 1.00 38.76 C ANISOU 1873 CA GLN B 392 4333 4849 5544 -1791 743 -474 C ATOM 1874 CB GLN B 392 2.892 -13.797 -11.814 1.00 42.01 C ANISOU 1874 CB GLN B 392 4577 5357 6027 -2076 791 -493 C ATOM 1875 CG GLN B 392 2.290 -13.588 -13.235 1.00 44.80 C ANISOU 1875 CG GLN B 392 4722 5861 6437 -2162 643 -595 C ATOM 1876 CD GLN B 392 3.258 -13.942 -14.391 1.00 51.20 C ANISOU 1876 CD GLN B 392 5712 6521 7222 -2125 497 -682 C ATOM 1877 OE1 GLN B 392 4.031 -14.910 -14.311 1.00 53.93 O ANISOU 1877 OE1 GLN B 392 6326 6621 7545 -2163 520 -686 O ATOM 1878 NE2 GLN B 392 3.209 -13.147 -15.476 1.00 51.38 N ANISOU 1878 NE2 GLN B 392 5589 6692 7241 -2037 355 -747 N ATOM 1879 C GLN B 392 4.181 -11.602 -11.782 1.00 36.21 C ANISOU 1879 C GLN B 392 3816 4724 5219 -1585 678 -496 C ATOM 1880 O GLN B 392 4.634 -11.118 -12.828 1.00 34.96 O ANISOU 1880 O GLN B 392 3629 4588 5067 -1495 542 -558 O ATOM 1881 N SER B 393 3.649 -10.860 -10.813 1.00 34.95 N ANISOU 1881 N SER B 393 3549 4690 5041 -1504 785 -445 N ATOM 1882 CA SER B 393 3.519 -9.411 -10.941 1.00 33.17 C ANISOU 1882 CA SER B 393 3168 4622 4815 -1299 742 -464 C ATOM 1883 CB SER B 393 2.667 -8.847 -9.825 1.00 34.13 C ANISOU 1883 CB SER B 393 3167 4880 4919 -1250 901 -417 C ATOM 1884 OG SER B 393 1.467 -9.579 -9.745 1.00 38.87 O ANISOU 1884 OG SER B 393 3599 5590 5579 -1467 999 -399 O ATOM 1885 C SER B 393 4.865 -8.711 -10.949 1.00 30.03 C ANISOU 1885 C SER B 393 2939 4115 4358 -1091 657 -471 C ATOM 1886 O SER B 393 5.056 -7.742 -11.689 1.00 28.60 O ANISOU 1886 O SER B 393 2679 3999 4189 -962 554 -508 O ATOM 1887 N ILE B 394 5.786 -9.209 -10.124 1.00 28.74 N ANISOU 1887 N ILE B 394 3005 3789 4128 -1066 696 -428 N ATOM 1888 CA ILE B 394 7.140 -8.694 -10.082 1.00 26.95 C ANISOU 1888 CA ILE B 394 2927 3464 3849 -898 609 -432 C ATOM 1889 CB ILE B 394 7.945 -9.231 -8.866 1.00 27.07 C ANISOU 1889 CB ILE B 394 3165 3341 3778 -867 665 -365 C ATOM 1890 CG1 ILE B 394 7.375 -8.668 -7.560 1.00 27.49 C ANISOU 1890 CG1 ILE B 394 3213 3475 3757 -823 791 -323 C ATOM 1891 CD1 ILE B 394 7.721 -9.498 -6.320 1.00 30.31 C ANISOU 1891 CD1 ILE B 394 3780 3722 4015 -857 877 -236 C ATOM 1892 CG2 ILE B 394 9.424 -8.817 -8.994 1.00 25.51 C ANISOU 1892 CG2 ILE B 394 3088 3060 3545 -716 547 -374 C ATOM 1893 C ILE B 394 7.863 -8.944 -11.412 1.00 25.54 C ANISOU 1893 C ILE B 394 2774 3223 3709 -900 476 -486 C ATOM 1894 O ILE B 394 8.505 -8.056 -11.939 1.00 24.61 O ANISOU 1894 O ILE B 394 2639 3128 3585 -774 387 -513 O ATOM 1895 N ALA B 395 7.737 -10.156 -11.945 1.00 26.28 N ANISOU 1895 N ALA B 395 2921 3231 3834 -1051 474 -504 N ATOM 1896 CA ALA B 395 8.278 -10.524 -13.247 1.00 25.51 C ANISOU 1896 CA ALA B 395 2857 3077 3758 -1069 369 -571 C ATOM 1897 CB ALA B 395 8.021 -12.026 -13.536 1.00 26.45 C ANISOU 1897 CB ALA B 395 3085 3062 3901 -1258 400 -593 C ATOM 1898 C ALA B 395 7.733 -9.662 -14.399 1.00 24.95 C ANISOU 1898 C ALA B 395 2600 3169 3712 -1056 277 -628 C ATOM 1899 O ALA B 395 8.500 -9.203 -15.243 1.00 22.82 O ANISOU 1899 O ALA B 395 2354 2893 3424 -962 190 -660 O ATOM 1900 N GLU B 396 6.413 -9.463 -14.442 1.00 26.63 N ANISOU 1900 N GLU B 396 2622 3534 3962 -1148 299 -631 N ATOM 1901 CA GLU B 396 5.790 -8.559 -15.438 1.00 27.37 C ANISOU 1901 CA GLU B 396 2521 3803 4073 -1108 201 -664 C ATOM 1902 CB GLU B 396 4.277 -8.475 -15.213 1.00 29.22 C ANISOU 1902 CB GLU B 396 2520 4221 4361 -1205 245 -652 C ATOM 1903 CG GLU B 396 3.527 -9.794 -15.523 1.00 32.18 C ANISOU 1903 CG GLU B 396 2860 4592 4773 -1475 256 -688 C ATOM 1904 CD GLU B 396 2.066 -9.807 -15.029 1.00 35.39 C ANISOU 1904 CD GLU B 396 3014 5189 5242 -1595 335 -660 C ATOM 1905 OE1 GLU B 396 1.642 -8.836 -14.337 1.00 37.14 O ANISOU 1905 OE1 GLU B 396 3100 5536 5475 -1443 406 -611 O ATOM 1906 OE2 GLU B 396 1.350 -10.800 -15.323 1.00 36.33 O ANISOU 1906 OE2 GLU B 396 3073 5331 5402 -1846 335 -690 O ATOM 1907 C GLU B 396 6.422 -7.145 -15.460 1.00 25.68 C ANISOU 1907 C GLU B 396 2306 3621 3832 -885 157 -642 C ATOM 1908 O GLU B 396 6.720 -6.591 -16.526 1.00 25.72 O ANISOU 1908 O GLU B 396 2290 3663 3819 -824.

51. 666 O ATOM 1909 N ALA B 397 6.661 -6.577 -14.284 1.00 24.70 N ANISOU 1909 N ALA B 397 2225 3468 3690 -776 239 -596 N ATOM 1910 CA ALA B 397 7.333 -5.290 -14.153 1.00 22.65 C ANISOU 1910 CA ALA B 397 2004 3200 3402 -591 205 -582 C ATOM 1911 CB ALA B 397 7.298 -4.867 -12.714 1.00 23.05 C ANISOU 1911 CB ALA B 397 2103 3231 3422 -516 311 -548 C ATOM 1912 C ALA B 397 8.789 -5.313 -14.662 1.00 21.56 C ANISOU 1912 C ALA B 397 2019 2943 3231 -547 131 -594 C ATOM 1913 O ALA B 397 9.232 -4.375 -15.328 1.00 21.06 O ANISOU 1913 O ALA B 397 1949 2897 3156 -455.

60. 597 O ATOM 1914 N ILE B 398 9.536 -6.365 -14.321 1.00 20.90 N ANISOU 1914 N ILE B 398 2071 2737 3132 -604 158 -592 N ATOM 1915 CA ILE B 398 10.913 -6.523 -14.788 1.00 20.40 C ANISOU 1915 CA ILE B 398 2124 2579 3048 -554 103 -603 C ATOM 1916 CB ILE B 398 11.619 -7.735 -14.116 1.00 20.53 C ANISOU 1916 CB ILE B 398 2288 2459 3053 -583 148 -585 C ATOM 1917 CG1 ILE B 398 11.713 -7.536 -12.597 1.00 20.53 C ANISOU 1917 CG1 ILE B 398 2348 2434 3017 -534 206 -527 C ATOM 1918 CD1 ILE B 398 12.047 -8.805 -11.842 1.00 22.94 C ANISOU 1918 CD1 ILE B 398 2798 2613 3304 -574 257 -485 C ATOM 1919 CG2 ILE B 398 13.040 -7.930 -14.677 1.00 20.38 C ANISOU 1919 CG2 ILE B 398 2352 2365 3024 -509.

97. 598 C ATOM 1920 C ILE B 398 10.967 -6.589 -16.325 1.00 20.24 C ANISOU 1920 C ILE B 398 2065 2595 3029 -586.

28. 652 C ATOM 1921 O ILE B 398 11.740 -5.886 -16.951 1.00 20.94 O ANISOU 1921 O ILE B 398 2167 2693 3098 -509 -23 -654 O ATOM 1922 N ILE B 399 10.109 -7.406 -16.920 1.00 21.51 N ANISOU 1922 N ILE B 399 2184 2784 3204 -714.

22. 692 N ATOM 1923 CA ILE B 399 10.015 -7.555 -18.364 1.00 20.76 C ANISOU 1923 CA ILE B 399 2067 2736 3085 -764 -55 -750 C ATOM 1924 CB ILE B 399 8.910 -8.566 -18.768 1.00 21.63 C ANISOU 1924 CB ILE B 399 2131 2876 3211 -946 -65 -802 C ATOM 1925 CG1 ILE B 399 9.288 -9.984 -18.311 1.00 22.66 C ANISOU 1925 CG1 ILE B 399 2424 2832 3354 -1040.

7. 825 C ATOM 1926 CD1 ILE B 399 8.135 -11.012 -18.342 1.00 22.92 C ANISOU 1926 CD1 ILE B 399 2427 2865 3418 -1259.

24. 864 C ATOM 1927 CG2 ILE B 399 8.658 -8.506 -20.279 1.00 19.65 C ANISOU 1927 CG2 ILE B 399 1844 2714 2910 -995 -171 -865 C ATOM 1928 C ILE B 399 9.770 -6.221 -19.068 1.00 21.46 C ANISOU 1928 C ILE B 399 2050 2953 3152 -676 -131 -730 C ATOM 1929 O ILE B 399 10.477 -5.901 -20.019 1.00 21.12 O ANISOU 1929 O ILE B 399 2054 2908 3061 -632 -180 -743 O ATOM 1930 N VAL B 400 8.760 -5.470 -18.605 1.00 22.28 N ANISOU 1930 N VAL B 400 2017 3161 3287 -643 -129 -693 N ATOM 1931 CA VAL B 400 8.423 -4.134 -19.122 1.00 21.58 C ANISOU 1931 CA VAL B 400 1838 3175 3186 -529 -194 -658 C ATOM 1932 CB VAL B 400 7.122 -3.570 -18.448 1.00 22.39 C ANISOU 1932 CB VAL B 400 1773 3394 3339 -487 -166 -626 C ATOM 1933 CG1 VAL B 400 6.830 -2.142 -18.873 1.00 21.87 C ANISOU 1933 CG1 VAL B 400 1642 3400 3267 -328 -226 -580 C ATOM 1934 CG2 VAL B 400 5.918 -4.465 -18.794 1.00 22.46 C ANISOU 1934 CG2 VAL B 400 1633 3525 3378 -639 -188 -659 C ATOM 1935 C VAL B 400 9.588 -3.144 -19.029 1.00 20.81 C ANISOU 1935 C VAL B 400 1846 2997 3063 -403 -194 -622 C ATOM 1936 O VAL B 400 9.846 -2.400 -19.974 1.00 21.60 O ANISOU 1936 O VAL B 400 1956 3127 3125 -349 -261 -603 O ATOM 1937 N ALA B 401 10.301 -3.154 -17.909 1.00 20.61 N ANISOU 1937 N ALA B 401 1904 2873 3052 -370 -125 -610 N ATOM 1938 CA ALA B 401 11.458 -2.262 -17.687 1.00 19.84 C ANISOU 1938 CA ALA B 401 1899 2702 2937 -283 -131 -583 C ATOM 1939 CB ALA B 401 11.879 -2.301 -16.225 1.00 19.17 C ANISOU 1939 CB ALA B 401 1879 2544 2860 -259 -68 -573 C ATOM 1940 C ALA B 401 12.637 -2.629 -18.608 1.00 19.90 C ANISOU 1940 C ALA B 401 1979 2670 2913 -310 -158 -597 C ATOM 1941 O ALA B 401 13.278 -1.758 -19.177 1.00 18.35 O ANISOU 1941 O ALA B 401 1809 2471 2693 -267 -189 -571 O ATOM 1942 N MSE B 402 12.894 -3.931 -18.781 1.00 20.40 N ANISOU 1942 N MSE B 402 2079 2699 2974 -381 -136 -638 N ATOM 1943 CA MSE B 402 13.954 -4.385 -19.707 1.00 20.55 C ANISOU 1943 CA MSE B 402 2161 2687 2958 -388 -140 -664 C ATOM 1944 CB MSE B 402 14.214 -5.888 -19.546 1.00 21.32 C ANISOU 1944 CB MSE B 402 2329 2705 3066 -438 -96 -712 C ATOM 1945 CG MSE B 402 14.859 -6.269 -18.205 1.00 19.84 C ANISOU 1945 CG MSE B 402 2193 2430 2916 -395 -51 -679 C ATOM 1946 SE MSE B 402 15.005 -8.198 -18.086 0.90 23.84 SE ANISOU 1946 SE MSE B 402 2821 2801 3435 -446.

4. 723 SE ATOM 1947 CE MSE B 402 16.111 -8.378 -16.488 1.00 20.10 C ANISOU 1947 CE MSE B 402 2411 2243 2983 -338.

29. 648 C ATOM 1948 C MSE B 402 13.680 -4.012 -21.179 1.00 20.87 C ANISOU 1948 C MSE B 402 2183 2810 2939 -405 -194 -677 C ATOM 1949 O MSE B 402 14.567 -3.492 -21.882 1.00 21.13 O ANISOU 1949 O MSE B 402 2248 2848 2930 -371 -196 -660 O ATOM 1950 N VAL B 403 12.449 -4.240 -21.642 1.00 20.78 N ANISOU 1950 N VAL B 403 2109 2873 2913 -463 -241 -701 N ATOM 1951 CA VAL B 403 12.053 -3.857 -22.988 1.00 19.97 C ANISOU 1951 CA VAL B 403 1987 2866 2733 -475 -317 -705 C ATOM 1952 CB VAL B 403 10.621 -4.369 -23.365 1.00 21.28 C ANISOU 1952 CB VAL B 403 2060 3133 2892 -566 -386 -744 C ATOM 1953 CG1 VAL B 403 10.175 -3.778 -24.723 1.00 21.74 C ANISOU 1953 CG1 VAL B 403 2093 3315 2853 -556 -494 -730 C ATOM 1954 CG2 VAL B 403 10.574 -5.860 -23.429 1.00 19.64 C ANISOU 1954 CG2 VAL B 403 1912 2867 2684 -694 -358 -835 C ATOM 1955 C VAL B 403 12.131 -2.338 -23.143 1.00 19.26 C ANISOU 1955 C VAL B 403 1877 2811 2630 -375 -351 -621 C ATOM 1956 O VAL B 403 12.691 -1.835 -24.114 1.00 18.91 O ANISOU 1956 O VAL B 403 1888 2786 2512 -354 -371 -595 O ATOM 1957 N PHE B 404 11.588 -1.610 -22.163 1.00 18.84 N ANISOU 1957 N PHE B 404 1763 2752 2642 -312 -343 -577 N ATOM 1958 CA PHE B 404 11.582 -0.161 -22.194 1.00 18.40 C ANISOU 1958 CA PHE B 404 1716 2693 2584 -208 -369 -502 C ATOM 1959 CB PHE B 404 10.817 0.351 -20.968 1.00 18.31 C ANISOU 1959 CB PHE B 404 1642 2669 2645 -138 -339 -486 C ATOM 1960 CG PHE B 404 10.743 1.833 -20.875 1.00 18.13 C ANISOU 1960 CG PHE B 404 1654 2608 2627 -16 -355 -420 C ATOM 1961 CD1 PHE B 404 9.712 2.526 -21.510 1.00 21.57 C ANISOU 1961 CD1 PHE B 404 2019 3125 305.

75. 424 -372 C ATOM 1962 CE1 PHE B 404 9.623 3.911 -21.415 1.00 19.89 C ANISOU 1962 CE1 PHE B 404 1867 2845 2845 209 -433 -306 C ATOM 1963 CZ PHE B 404 10.559 4.622 -20.695 1.00 19.02 C ANISOU 1963 CZ PHE B 404 1892 2583 2751 222 -377 -301 C ATOM 1964 CE2 PHE B 404 11.600 3.964 -20.055 1.00 17.62 C ANISOU 1964 CE2 PHE B 404 1765 2349 2583 115 -323 -353 C ATOM 1965 CD2 PHE B 404 11.686 2.554 -20.149 1.00 18.96 C ANISOU 1965 CD2 PHE B 404 1868 2590 274.

11. 311 -406 C ATOM 1966 C PHE B 404 13.000 0.452 -22.282 1.00 17.86 C ANISOU 1966 C PHE B 404 1756 2534 2495 -193 -334 -470 C ATOM 1967 O PHE B 404 13.187 1.520 -22.880 1.00 18.45 O ANISOU 1967 O PHE B 404 1877 2601 2533 -147 -362 -406 O ATOM 1968 N SER B 405 13.981 -0.215 -21.670 1.00 17.56 N ANISOU 1968 N SER B 405 1754 2433 2485 -234 -273 -506 N ATOM 1969 CA SER B 405 15.373 0.264 -21.614 1.00 17.50 C ANISOU 1969 CA SER B 405 1807 2365 2476 -236 -240 -480 C ATOM 1970 CB SER B 405 16.229 -0.605 -20.689 1.00 17.20 C ANISOU 1970 CB SER B 405 1772 2280 2483 -256 -192 -518 C ATOM 1971 OG SER B 405 16.462 -1.911 -21.262 1.00 20.67 O ANISOU 1971 OG SER B 405 2216 2738 2901 -289 -164 -571 O ATOM 1972 C SER B 405 16.025 0.316 -22.998 1.00 17.94 C ANISOU 1972 C SER B 405 1898 2462 2456 -265 -235 -464 C ATOM 1973 O SER B 405 16.989 1.044 -23.203 1.00 18.90 O ANISOU 1973 O SER B 405 2055 2558 2568 -275 -210 -418 O ATOM 1974 N GLN B 406 15.494 -0.461 -23.935 1.00 18.28 N ANISOU 1974 N GLN B 406 1937 2573 2437 -291 -256 -504 N ATOM 1975 CA GLN B 406 16.000 -0.549 -25.304 1.00 19.28 C ANISOU 1975 CA GLN B 406 2116 2752 2458 -318 -243 -503 C ATOM 1976 CB GLN B 406 15.955 0.817 -25.999 1.00 19.35 C ANISOU 1976 CB GLN B 406 2167 2777 2406 -291 -278 -404 C ATOM 1977 CG GLN B 406 14.532 1.352 -26.113 1.00 20.49 C ANISOU 1977 CG GLN B 406 2281 2965 2539 -240 -379 -367 C ATOM 1978 CD GLN B 406 14.456 2.710 -26.785 1.00 22.34 C ANISOU 1978 CD GLN B 406 2584 3192 2713 -188 -418 -254 C ATOM 1979 OE1 GLN B 406 15.224 3.623 -26.471 1.00 20.91 O ANISOU 1979 OE1 GLN B 406 2462 2918 2562 -184 -372 -193 O ATOM 1980 NE2 GLN B 406 13.519 2.849 -27.714 1.00 20.46 N ANISOU 1980 NE2 GLN B 406 2345 3047 2383 -154 -512 -221 N ATOM 1981 C GLN B 406 17.374 -1.207 -25.426 1.00 19.38 C ANISOU 1981 C GLN B 406 2150 2743 2469 -335 -149 -539 C ATOM 1982 O GLN B 406 18.039 -1.028 -26.432 1.00 21.03 O ANISOU 1982 O GLN B 406 2400 2994 2595 -348 -107 -522 O ATOM 1983 N GLU B 407 17.781 -1.976 -24.415 1.00 18.80 N ANISOU 1983 N GLU B 407 2049 2614 2481 -325 -113 -581 N ATOM 1984 CA GLU B 407 19.109 -2.576 -24.370 1.00 19.09 C ANISOU 1984 CA GLU B 407 2080 2636 2537 -307 -605 C ATOM 1985 CB GLU B 407 19.365 -3.321 -23.048 1.00 18.52 C ANISOU 1985 CB GLU B 407 1981 2495 2561 -275 -21 -629 C ATOM 1986 CG GLU B 407 19.622 -2.433 -21.859 1.00 18.23 C ANISOU 1986 CG GLU B 407 1904 2432 2593 -268 -55 -571 C ATOM 1987 CD GLU B 407 20.657 -2.959 -20.879 1.00 20.08 C ANISOU 1987 CD GLU B 407 2101 2638 2890 -228 -36 -571 C ATOM 1988 OE1 GLU B 407 21.347 -3.968 -21.157 1.00 24.36 O ANISOU 1988 OE1 GLU B 407 2638 3181 3437 -183.

17. 605 O ATOM 1989 OE2 GLU B 407 20.803 -2.340 -19.816 1.00 15.98 O ANISOU 1989 OE2 GLU B 407 1565 2098 2410 -232 -77 -538 O ATOM 1990 C GLU B 407 19.347 -3.519 -25.533 1.00 20.61 C ANISOU 1990 C GLU B 407 2328 2862 2643 -309.

25. 675 C ATOM 1991 O GLU B 407 18.464 -4.263 -25.933 1.00 20.40 O ANISOU 1991 O GLU B 407 2351 2831 2570 -338 -7 -741 O ATOM 1992 N ASP B 408 20.557 -3.455 -26.078 1.00 21.85 N ANISOU 1992 N ASP B 408 2473 3056 2773 -287 113 -666 N ATOM 1993 CA ASP B 408 20.990 -4.385 -27.121 1.00 23.75 C ANISOU 1993 CA ASP B 408 2775 3323 2925 -264 199 -744 C ATOM 1994 CB ASP B 408 22.417 -4.035 -27.600 1.00 24.31 C ANISOU 1994 CB ASP B 408 2792 3464 2982 -234 316 -708 C ATOM 1995 CG ASP B 408 22.868 -4.897 -28.750 1.00 28.24 C ANISOU 1995 CG ASP B 408 3363 3999 3369 -193 429 -792 C ATOM 1996 OD1 ASP B 408 22.218 -4.835 -29.818 1.00 30.42 O ANISOU 1996 OD1 ASP B 408 3745 4314 3501 -240 412 -821 O ATOM 1997 OD2 ASP B 408 23.858 -5.658 -28.585 1.00 29.98 O ANISOU 1997 OD2 ASP B 408 3540 4212 3639 -103 531 -834 O ATOM 1998 C ASP B 408 20.919 -5.851 -26.691 1.00 23.93 C ANISOU 1998 C ASP B 408 2843 3258 2993 -219 222 -841 C ATOM 1999 O ASP B 408 20.644 -6.717 -27.523 1.00 26.33 O ANISOU 1999 O ASP B 408 3249 3545 3209 -226 252 -934 O ATOM 2000 N ACYS B 409 21.157 -6.152 -25.422 0.50 23.03 N ANISOU 2000 N ACYS B 409 2677 3074 2999 -178 208 -820 N ATOM 2001 N BCYS B 409 21.192 -6.118 -25.410 0.50 23.70 N ANISOU 2001 N BCYS B 409 2758 3161 3085 -177 209 -817 N ATOM 2002 CA ACYS B 409 21.117 -7.552 -25.013 0.50 23.05 C ANISOU 2002 CA ACYS B 409 2751 2969 3040 -130 237 -894 C ATOM 2003 CA BCYS B 409 21.114 -7.471 -24.832 0.50 24.45 C ANISOU 2003 CA BCYS B 409 2916 3144 3231 -129 228 -883 C ATOM 2004 CB ACYS B 409 21.870 -7.779 -23.708 0.50 22.54 C ANISOU 2004 CB ACYS B 409 2619 2853 3090 -46 240 -844 C ATOM 2005 CB BCYS B 409 21.537 -7.471 -23.355 0.50 23.66 C ANISOU 2005 CB BCYS B 409 2747 2996 3247 -76 201 -820 C ATOM 2006 SG ACYS B 409 20.881 -7.846 -22.247 0.50 20.66 S ANISOU 2006 SG ACYS B 409 2393 2533 2922 -91 150 -805 S ATOM 2007 SG BCYS B 409 23.267 -7.970 -23.032 0.50 30.51 S ANISOU 2007 SG BCYS B 409 3537 3875 4180 76 284 -802 S ATOM 2008 C ACYS B 409 19.678 -8.084 -24.950 0.50 23.04 C ANISOU 2008 C ACYS B 409 2832 2904 3018 -222 165 -946 C ATOM 2009 C BCYS B 409 19.704 -8.048 -24.956 0.50 23.79 C ANISOU 2009 C BCYS B 409 2924 3003 3114 -220 166 -944 C ATOM 2010 O ACYS B 409 19.462 -9.292 -25.088 0.50 23.63 O ANISOU 2010 O ACYS B 409 3015 2881 3084 -225 195 -1031 O ATOM 2011 O BCYS B 409 19.535 -9.243 -25.224 0.50 24.43 O ANISOU 2011 O BCYS B 409 3115 2992 3174 -221 200 -1033 O ATOM 2012 N MSE B 410 18.715 -7.174 -24.763 1.00 22.13 N ANISOU 2012 N MSE B 410 2663 2845 2900 -296.

77. 895 N ATOM 2013 CA MSE B 410 17.291 -7.506 -24.815 1.00 22.65 C ANISOU 2013 CA MSE B 410 2756 2901 2947 -395.

4. 935 C ATOM 2014 CB MSE B 410 16.469 -6.363 -24.180 1.00 22.12 C ANISOU 2014 CB MSE B 410 2589 2896 2920 -418 -73 -851 C ATOM 2015 CG MSE B 410 14.919 -6.489 -24.305 1.00 23.37 C ANISOU 2015 CG MSE B 410 2717 3098 3064 -513 -154 -876 C ATOM 2016 SE MSE B 410 14.089 -5.800 -25.963 0.90 26.60 SE ANISOU 2016 SE MSE B 410 3114 3662 3331 -562 -257 -885 SE ATOM 2017 CE MSE B 410 14.915 -4.026 -25.917 1.00 18.43 C ANISOU 2017 CE MSE B 410 2040 2665 2297 -451 -245 -752 C ATOM 2018 C MSE B 410 16.832 -7.795 -26.261 1.00 24.21 C ANISOU 2018 C MSE B 410 3030 3154 3015 -459 -18 -1015 C ATOM 2019 O MSE B 410 16.097 -8.758 -26.507 1.00 26.05 O ANISOU 2019 O MSE B 410 3337 3340 3223 -543 -42 -1103 O ATOM 2020 N ILE B 411 17.279 -6.966 -27.209 1.00 23.73 N ANISOU 2020 N ILE B 411 2964 3190 2862 -434 -984 N ATOM 2021 CA ILE B 411 16.968 -7.127 -28.621 1.00 24.58 C ANISOU 2021 CA ILE B 411 3159 3368 2813 -484 -31 -1049 C ATOM 2022 CB ILE B 411 17.364 -5.833 -29.388 1.00 25.91 C ANISOU 2022 CB ILE B 411 3303 3651 2892 -455 -32 -956 C ATOM 2023 CG1 ILE B 411 16.275 -4.775 -29.197 1.00 25.08 C ANISOU 2023 CG1 ILE B 411 3119 3612 2799 -483 -161 -866 C ATOM 2024 CD1 ILE B 411 16.743 -3.369 -29.342 1.00 27.19 C ANISOU 2024 CD1 ILE B 411 3355 3923 3051 -438 -154 -740 C ATOM 2025 CG2 ILE B 411 17.488 -6.094 -30.859 1.00 27.26 C ANISOU 2025 CG2 ILE B 411 3593 3891 2874 -479 -9 -1022 C ATOM 2026 C ILE B 411 17.630 -8.389 -29.207 1.00 25.31 C ANISOU 2026 C ILE B 411 3387 3383 2845 -464.

69. 1174 C ATOM 2027 O ILE B 411 17.036 -9.078 -30.020 1.00 25.74 O ANISOU 2027 O ILE B 411 3553 3436 2793 -541.

34. 1280 O ATOM 2028 N LYS B 412 18.851 -8.695 -28.771 1.00 24.46 N ANISOU 2028 N LYS B 412 3273 3215 2808 -354 188 -1167 N ATOM 2029 CA LYS B 412 19.531 -9.938 -29.166 1.00 25.83 C ANISOU 2029 CA LYS B 412 3574 3291 2950 -290 300 -1283 C ATOM 2030 CB LYS B 412 21.037 -9.850 -28.886 1.00 25.21 C ANISOU 2030 CB LYS B 412 3423 3220 2935 -138 430 -1237 C ATOM 2031 CG LYS B 412 21.773 -8.806 -29.742 1.00 23.92 C ANISOU 2031 CG LYS B 412 3193 3213 2684 -119 493 -1176 C ATOM 2032 CD LYS B 412 21.678 -9.165 -31.220 1.00 22.65 C ANISOU 2032 CD LYS B 412 3183 3097 2327 -142 550 -1280 C ATOM 2033 CE LYS B 412 22.511 -8.236 -32.094 1.00 20.84 C ANISOU 2033 CE LYS B 412 2906 3018 1995 -121 647 -1213 C ATOM 2034 NZ LYS B 412 21.948 -6.857 -32.071 1.00 20.43 N ANISOU 2034 NZ LYS B 412 2781 3055 1928 -215 534 -1081 N ATOM 2035 C LYS B 412 18.949 -11.213 -28.536 1.00 26.84 C ANISOU 2035 C LYS B 412 3802 3249 3147 -329 281 -1365 C ATOM 2036 O LYS B 412 19.226 -12.299 -29.012 1.00 28.99 O ANISOU 2036 O LYS B 412 4229 3413 3371 -300 355 -1482 O ATOM 2037 N ALA B 413 18.131 -11.068 -27.497 1.00 26.02 N ANISOU 2037 N ALA B 413 3625 3115 3145 -398 193 -1304 N ATOM 2038 CA ALA B 413 17.459 -12.202 -26.858 1.00 27.44 C ANISOU 2038 CA ALA B 413 3899 3138 3389 -471 177 -1361 C ATOM 2039 CB ALA B 413 17.107 -11.851 -25.376 1.00 25.11 C ANISOU 2039 CB ALA B 413 3488 2823 3229 -476 137 -1246 C ATOM 2040 C ALA B 413 16.215 -12.670 -27.635 1.00 29.24 C ANISOU 2040 C ALA B 413 4212 3372 3526 -653.

93. 1466 C ATOM 2041 O ALA B 413 15.635 -13.725 -27.336 1.00 30.83 O ANISOU 2041 O ALA B 413 4521 3433 3761 -753.

87. 1536 O ATOM 2042 N VAL B 414 15.801 -11.893 -28.634 1.00 30.33 N ANISOU 2042 N VAL B 414 4307 3674 3544 -707.

19. 1472 N ATOM 2043 CA VAL B 414 14.651 -12.269 -29.456 1.00 31.87 C ANISOU 2043 CA VAL B 414 4563 3912 3634 -882 -88 -1572 C ATOM 2044 CB VAL B 414 14.201 -11.126 -30.389 1.00 31.88 C ANISOU 2044 CB VAL B 414 4477 4127 3508 -905 -194 -1526 C ATOM 2045 CG1 VAL B 414 13.206 -11.626 -31.408 1.00 31.91 C ANISOU 2045 CG1 VAL B 414 4563 4190 3369 -1074 -313 -1646 C ATOM 2046 CG2 VAL B 414 13.590 -10.006 -29.588 1.00 28.46 C ANISOU 2046 CG2 VAL B 414 3837 3799 3177 -893 -273 -1380 C ATOM 2047 C VAL B 414 14.958 -13.532 -30.257 1.00 35.11 C ANISOU 2047 C VAL B 414 5209 4187 3946 -914 -25 -1742 C ATOM 2048 O VAL B 414 16.029 -13.670 -30.835 1.00 35.73 O ANISOU 2048 O VAL B 414 5385 4238 3952 -784.

89. 1784 O ATOM 2049 N ARG B 415 14.009 -14.465 -30.261 1.00 37.91 N ANISOU 2049 N ARG B 415 5655 4449 4300 -1095 -89 -1844 N ATOM 2050 CA ARG B 415 14.141 -15.699 -31.006 1.00 40.89 C ANISOU 2050 CA ARG B 415 6289 4669 4580 -1157 -43 -2026 C ATOM 2051 CB ARG B 415 14.084 -16.913 -30.063 1.00 42.00 C ANISOU 2051 CB ARG B 415 6555 4547 4856 -1201.

23. 2063 C ATOM 2052 CG ARG B 415 15.271 -17.043 -29.108 1.00 41.66 C ANISOU 2052 CG ARG B 415 6513 4373 4942 -969 167 -1969 C ATOM 2053 CD ARG B 415 16.615 -17.211 -29.848 1.00 43.44 C ANISOU 2053 CD ARG B 415 6857 4564 5085 -754 304 -2032 C ATOM 2054 NE ARG B 415 17.736 -17.257 -28.906 1.00 44.27 N ANISOU 2054 NE ARG B 415 6911 4587 5323 -528 418 -1927 N ATOM 2055 CZ ARG B 415 18.535 -16.226 -28.622 1.00 44.39 C ANISOU 2055 CZ ARG B 415 6727 4761 5378 -377 446 -1798 C ATOM 2056 NH1 ARG B 415 18.363 -15.052 -29.226 1.00 42.41 N ANISOU 2056 NH1 ARG B 415 6333 4736 5045 -419 386 -1752 N ATOM 2057 NH2 ARG B 415 19.524 -16.371 -27.736 1.00 42.84 N ANISOU 2057 NH2 ARG B 415 6481 4495 5301 -187 528 -1712 N ATOM 2058 C ARG B 415 13.024 -15.753 -32.047 1.00 42.87 C ANISOU 2058 C ARG B 415 6576 5039 4676 -1373 -200 -2134 C ATOM 2059 O ARG B 415 11.836 -15.538 -31.722 1.00 43.41 O ANISOU 2059 O ARG B 415 6496 5203 4795 -1543 -339 -2096 O ATOM 2060 N GLY B 416 13.414 -16.003 -33.295 1.00 43.58 N ANISOU 2060 N GLY B 416 6847 5143 4569 -1359 -179 -2265 N ATOM 2061 CA GLY B 416 12.471 -16.015 -34.399 1.00 44.83 C ANISOU 2061 CA GLY B 416 7057 5437 4540 -1552 -342 -2373 C ATOM 2062 C GLY B 416 12.035 -14.620 -34.801 1.00 43.68 C ANISOU 2062 C GLY B 416 6698 5579 4320 -1531 -474 -2238 C ATOM 2063 O GLY B 416 12.426 -13.636 -34.182 1.00 40.62 O ANISOU 2063 O GLY B 416 6131 5266 4039 -1383 -433 -2066 O ATOM 2064 N ASP B 417 11.220 -14.550 -35.849 1.00 45.98 N ANISOU 2064 N ASP B 417 7025 6022 4422 -1682 -641 -2318 N ATOM 2065 CA ASP B 417 10.713 -13.285 -36.381 1.00 46.13 C ANISOU 2065 CA ASP B 417 6873 6313 4341 -1660 -791 -2193 C ATOM 2066 CB ASP B 417 10.301 -13.462 -37.856 1.00 49.03 C ANISOU 2066 CB ASP B 417 7403 6811 4417 -1778 -927 -2325 C ATOM 2067 CG ASP B 417 11.490 -13.487 -38.803 1.00 49.91 C ANISOU 2067 CG ASP B 417 7750 6890 4322 -1638 -771 -2389 C ATOM 2068 OD1 ASP B 417 12.611 -13.144 -38.380 1.00 49.40 O ANISOU 2068 OD1 ASP B 417 7671 6752 4348 -1440 -575 -2299 O ATOM 2069 OD2 ASP B 417 11.303 -13.843 -39.981 1.00 54.40 O ANISOU 2069 OD2 ASP B 417 8515 7522 4632 -1731 -844 -2530 O ATOM 2070 C ASP B 417 9.534 -12.731 -35.573 1.00 45.38 C ANISOU 2070 C ASP B 417 6492 6343 4409 -1743 -943 -2070 C ATOM 2071 O ASP B 417 8.746 -13.487 -34.982 1.00 46.51 O ANISOU 2071 O ASP B 417 6586 6417 4670 -1916 -994 -2131 O ATOM 2072 N LEU B 418 9.403 -11.409 -35.575 1.00 44.04 N ANISOU 2072 N LEU B 418 6141 6353 4239 -1621 -1007 -1897 N ATOM 2073 CA LEU B 418 8.293 -10.755 -34.905 1.00 43.53 C ANISOU 2073 CA LEU B 418 5799 6428 4311 -1656 -1143 -1777 C ATOM 2074 CB LEU B 418 8.810 -9.653 -33.980 1.00 40.59 C ANISOU 2074 CB LEU B 418 5283 6046 4093 -1450 -1042 -1589 C ATOM 2075 CG LEU B 418 9.808 -10.051 -32.878 1.00 38.75 C ANISOU 2075 CG LEU B 418 5100 5593 4029 -1362 -833 -1577 C ATOM 2076 CD1 LEU B 418 10.306 -8.834 -32.112 1.00 35.47 C ANISOU 2076 CD1 LEU B 418 4554 5196 3728 -1178 -766 -1401 C ATOM 2077 CD2 LEU B 418 9.250 -11.068 -31.915 1.00 39.40 C

ANISOU 2077 CD2 LEU B 418 5149 5552 4270 -1500 -811 -1642 C

ATOM 2078 C LEU B 418 7.241 -10.235 -35.898 1.00 45.84 C

ANISOU 2078 C LEU B 418 6001 6978 4439 -1735 -1384 -1763 C

ATOM 2079 O LEU B 418 7.535 -9.394 -36.757 1.00 46.01 O

ANISOU 2079 O LEU B 418 6071 7120 4290 -1621 -1431 -1691 O

ATOM 2080 N ASN B 419 6.020 -10.759 -35.773 1.00 47.64 N

ANISOU 2080 N ASN B 419 6094 7293 4714 -1936 -1539 -1827 N

ATOM 2081 CA ASN B 419 4.923 -10.448 -36.687 1.00 50.61 C

ANISOU 2081 CA ASN B 419 6358 7932 4940 -2038 -1799 -1833 C

ATOM 2082 CB ASN B 419 4.793 -11.549 -37.747 1.00 53.52 C

ANISOU 2082 CB ASN B 419 6955 8284 5095 -2259 -1891 -2052 C

ATOM 2083 CG ASN B 419 5.967 -11.586 -38.713 1.00 54.69 C

ANISOU 2083 CG ASN B 419 7420 8348 5013 -2152 -1783 -2116 C

ATOM 2084 OD1 ASN B 419 6.257 -10.605 -39.409 1.00 55.78 O

ANISOU 2084 OD1 ASN B 419 7577 8623 4994 -1997 -1823 -2005 O

ATOM 2085 ND2 ASN B 419 6.645 -12.728 -38.767 1.00 55.63 N

ANISOU 2085 ND2 ASN B 419 7797 8235 5105 -2228 -1634 -2293 N

ATOM 2086 C ASN B 419 3.565 -10.242 -35.997 1.00 51.57 C

ANISOU 2086 C ASN B 419 6141 8219 5233 -2130 -1940 -1764 C

ATOM 2087 O ASN B 419 2.515 -10.554 -36.574 1.00 54.24 O

ANISOU 2087 O ASN B 419 6375 8743 5492 -2316 -2156 -1834 O

ATOM 2088 N PHE B 420 3.590 -9.705 -34.776 1.00 49.62 N

ANISOU 2088 N PHE B 420 5719 7922 5214 -1998 -1820 -1630 N

ATOM 2089 CA PHE B 420 2.373 -9.504 -33.976 1.00 50.02 C

ANISOU 2089 CA PHE B 420 5439 8121 5445 -2058 -1900 -1560 C

ATOM 2090 CB PHE B 420 2.712 -9.101 -32.538 1.00 47.52 C

ANISOU 2090 CB PHE B 420 5026 7673 5357 -1910 -1701 -1445 C

ATOM 2091 CG PHE B 420 3.276 -10.218 -31.721 1.00 47.20 C

ANISOU 2091 CG PHE B 420 5137 7373 5425 -2025 -1514 -1537 C

ATOM 2092 CD1 PHE B 420 4.620 -10.241 -31.399 1.00 44.34 C

ANISOU 2092 CD1 PHE B 420 4992 6786 5070 -1880 -1326 -1527 C

ATOM 2093 CE1 PHE B 420 5.152 -11.271 -30.647 1.00 43.10 C

ANISOU 2093 CE1 PHE B 420 4980 6389 5008 -1957 -1165 -1597 C

ATOM 2094 CZ PHE B 420 4.344 -12.302 -30.207 1.00 45.97 C

ANISOU 2094 CZ PHE B 420 5299 6709 5458 -2199 -1177 -1678 C

ATOM 2095 CE2 PHE B 420 2.993 -12.306 -30.516 1.00 48.22 C

ANISOU 2095 CE2 PHE B 420 5362 7217 5743 -2379 -1352 -1696 C

ATOM 2096 CD2 PHE B 420 2.461 -11.261 -31.273 1.00 49.98 C

ANISOU 2096 CD2 PHE B 420 5411 7705 5873 -2283 -1527 -1627 C

ATOM 2097 C PHE B 420 1.406 -8.507 -34.584 1.00 51.27 C

ANISOU 2097 C PHE B 420 5363 8585 5534 -1978 -2129 -1452 C

ATOM 2098 O PHE B 420 1.809 -7.486 -35.147 1.00 50.92 O

ANISOU 2098 O PHE B 420 5373 8599 5374 -1767 -2166 -1341 O

ATOM 2099 N VAL B 421 0.124 -8.817 -34.417 1.00 53.07 N

ANISOU 2099 N VAL B 421 5320 9003 5842 -2148 -2275 -1475 N

ATOM 2100 CA VAL B 421 -0.949 -8.217 -35.197 1.00 55.35 C

ANISOU 2100 CA VAL B 421 5378 9617 6037 -2138 -2546 -1417 C

ATOM 2101 CB VAL B 421 -1.320 -9.170 -36.362 1.00 58.38 C

ANISOU 2101 CB VAL B 421 5876 10095 6212 -2420 -2749 -1597 C

ATOM 2102 CG1 VAL B 421 -2.801 -9.548 -36.346 1.00 62.13 C

ANISOU 2102 CG1 VAL B 421 6005 10842 6760 -2651 -2962 -1635 C

ATOM 2103 CG2 VAL B 421 -0.857 -8.594 -37.696 1.00 59.48 C

ANISOU 2103 CG2 VAL B 421 6222 10317 6062 -2293 -2882 -1575 C

ATOM 2104 C VAL B 421 -2.181 -7.818 -34.375 1.00 55.75 C

ANISOU 2104 C VAL B 421 5010 9876 6297 -2121 -2603 -1318 C

ATOM 2105 O VAL B 421 -2.233 -7.998 -33.161 1.00 53.74 O

ANISOU 2105 O VAL B 421 4650 9514 6255 -2128 -2419 -1295 O

ATOM 2106 N ALA B 424 -8.330 -7.054 -34.316 1.00 83.41 N

ANISOU 2106 N ALA B 424 6624 14886 10180 -2373 -3433 -1118 N

ATOM 2107 CA ALA B 424 -8.109 -5.823 -35.078 1.00 83.39 C

ANISOU 2107 CA ALA B 424 6684 14974 10028 -2016 -3575 -972 C

ATOM 2108 CB ALA B 424 -7.502 -4.750 -34.179 1.00 80.03 C

ANISOU 2108 CB ALA B 424 6321 14356 9729 -1638 -3328 -816 C

ATOM 2109 C ALA B 424 -7.235 -6.044 -36.325 1.00 83.09 C

ANISOU 2109 C ALA B 424 7065 14815 9689 -2072 -3692 -1054 C

ATOM 2110 O ALA B 424 -7.422 -5.385 -37.357 1.00 84.69 O

ANISOU 2110 O ALA B 424 7275 15205 9698 -1925 -3931 -976 O

ATOM 2111 N ASN B 425 -6.283 -6.973 -36.206 1.00 81.03 N

ANISOU 2111 N ASN B 425 7157 14244 9387 -2271 -3512 -1204 N

ATOM 2112 CA ASN B 425 -5.300 -7.305 -37.262 1.00 80.26 C

ANISOU 2112 CA ASN B 425 7495 13986 9016 -2326 -3549 -1305 C

ATOM 2113 CB ASN B 425 -5.987 -7.797 -38.555 1.00 84.45 C

ANISOU 2113 CB ASN B 425 8001 14775 9309 -2559 -3886 -1417 C

ATOM 2114 CG ASN B 425 -5.041 -8.595 -39.454 1.00 84.90 C

ANISOU 2114 CG ASN B 425 8524 14628 9108 -2728 -3870 -1597 C

ATOM 2115 OD1 ASN B 425 -4.463 -9.623 -39.028 1.00 84.50 O

ANISOU 2115 OD1 ASN B 425 8690 14300 9116 -2930 -3673 -1754 O

ATOM 2116 ND2 ASN B 425 -4.880 -8.118 -40.700 1.00 86.24 N

ANISOU 2116 ND2 ASN B 425 8858 14929 8980 -2630 -4069 -1569 N

ATOM 2117 C ASN B 425 -4.251 -6.211 -37.547 1.00 77.13 C

ANISOU 2117 C ASN B 425 7357 13442 8505 -1975 -3451 -1163 C

ATOM 2118 O ASN B 425 -3.579 -6.224 -38.607 1.00 77.12 O

ANISOU 2118 O ASN B 425 7668 13393 8242 -1971 -3519 -1205 O

ATOM 2119 N GLN B 426 -4.098 -5.287 -36.579 1.00 74.28 N

ANISOU 2119 N GLN B 426 6881 13003 8337 -1698 -3278 -1003 N

ATOM 2120 CA GLN B 426 -3.150 -4.184 -36.730 1.00 71.77 C

ANISOU 2120 CA GLN B 426 6789 12536 7944 -1383 -3177 -858 C

ATOM 2121 CB GLN B 426 -3.642 -2.945 -35.979 1.00 71.41 C

ANISOU 2121 CB GLN B 426 6489 12565 8078 -1069 -3143 -660 C

ATOM 2122 CG GLN B 426 -4.259 -1.900 -36.902 1.00 75.93 C

ANISOU 2122 CG GLN B 426 6956 13384 8510 -844 -3402 -501 C

ATOM 2123 CD GLN B 426 -5.489 -1.238 -36.301 1.00 79.00 C

ANISOU 2123 CD GLN B 426 6914 14008 9093 -664 -3487 -379 C

ATOM 2124 OE1 GLN B 426 -5.395 -0.480 -35.325 1.00 77.23 O

ANISOU 2124 OE1 GLN B 426 6622 13667 9055 -431 -3303 -275 O

ATOM 2125 NE2 GLN B 426 -6.657 -1.526 -36.882 1.00 82.04 N

ANISOU 2125 NE2 GLN B 426 7000 14737 9434 -772 -3766 -397 N

ATOM 2126 C GLN B 426 -1.744 -4.552 -36.272 1.00 67.70 C

ANISOU 2126 C GLN B 426 6612 11664 7446 -1398 -2889 -925 C

ATOM 2127 O GLN B 426 -1.531 -4.823 -35.079 1.00 65.90 O

ANISOU 2127 O GLN B 426 6334 11273 7433 -1414 -2675 -943 O

ATOM 2128 N ARG B 427 -0.793 -4.546 -37.212 1.00 66.20 N

ANISOU 2128 N ARG B 427 6756 11371 7026 -1382 -2882 -954 N

ATOM 2129 CA ARG B 427 0.612 -4.844 -36.900 1.00 62.42 C

ANISOU 2129 CA ARG B 427 6586 10583 6550 -1372 -2617 -1008 C

ATOM 2130 CB ARG B 427 1.461 -4.982 -38.166 1.00 63.31 C

ANISOU 2130 CB ARG B 427 7032 10653 6369 -1395 -2643 -1064 C

ATOM 2131 CG ARG B 427 2.893 -5.323 -37.824 1.00 60.44 C

ANISOU 2131 CG ARG B 427 6941 9997 6027 -1376 -2363 -1121 C

ATOM 2132 CD ARG B 427 3.839 -5.274 -38.987 1.00 62.17 C

ANISOU 2132 CD ARG B 427 7475 10176 5972 -1350 -2335 -1148 C

ATOM 2133 NE ARG B 427 5.192 -5.498 -38.488 1.00 60.41 N

ANISOU 2133 NE ARG B 427 7440 9693 5819 -1299 -2053 -1179 N

ATOM 2134 CZ ARG B 427 5.789 -6.686 -38.435 1.00 61.00 C

ANISOU 2134 CZ ARG B 427 7681 9608 5886 -1440 -1921 -1360 C

ATOM 2135 NH1 ARG B 427 5.165 -7.770 -38.880 1.00 62.69 N

ANISOU 2135 NH1 ARG B 427 7932 9872 6017 -1663 -2042 -1538 N

ATOM 2136 NH2 ARG B 427 7.015 -6.789 -37.940 1.00 59.05 N

ANISOU 2136 NH2 ARG B 427 7568 9150 5718 -1357 -1675 -1364 N

ATOM 2137 C ARG B 427 1.276 -3.851 -35.925 1.00 58.46 C

ANISOU 2137 C ARG B 427 6084 9911 6216 -1119 -2409 -857 C

ATOM 2138 O ARG B 427 1.461 -2.673 -36.244 1.00 58.25 O

ANISOU 2138 O ARG B 427 6093 9913 6128 -892 -2441 -697 O

ATOM 2139 N LEU B 428 1.661 -4.365 -34.758 1.00 55.08 N

ANISOU 2139 N LEU B 428 5646 9295 5987 -1171 -2200 -912 N

ATOM 2140 CA LEU B 428 2.179 -3.563 -33.637 1.00 51.23 C

ANISOU 2140 CA LEU B 428 5136 8653 5678 -972 -2010 -796 C

ATOM 2141 CB LEU B 428 2.409 -4.453 -32.403 1.00 49.31 C

ANISOU 2141 CB LEU B 428 4870 8241 5623 -1094 -1820 -888 C

ATOM 2142 CG LEU B 428 1.337 -5.465 -31.970 1.00 49.76 C

ANISOU 2142 CG LEU B 428 4722 8398 5786 -1320 -1873 -988 C

ATOM 2143 CD1 LEU B 428 1.713 -6.150 -30.667 1.00 44.96 C

ANISOU 2143 CD1 LEU B 428 4138 7589 5355 -1393 -1657 -1034 C

ATOM 2144 CD2 LEU B 428 -0.032 -4.799 -31.836 1.00 52.31 C

ANISOU 2144 CD2 LEU B 428 4701 8986 6189 -1248 -2023 -893 C

ATOM 2145 C LEU B 428 3.472 -2.848 -33.998 1.00 48.96 C

ANISOU 2145 C LEU B 428 5109 8206 5286 -819 -1897 -722 C

ATOM 2146 O LEU B 428 4.238 -3.337 -34.840 1.00 49.40 O

ANISOU 2146 O LEU B 428 5395 8205 5171 -902 -1877 -801 O

ATOM 2147 N ASN B 429 3.711 -1.694 -33.375 1.00 46.41 N

ANISOU 2147 N ASN B 429 4755 7813 5065 -605 -1817 -577 N

ATOM 2148 CA ASN B 429 4.977 -1.001 -33.559 1.00 43.84 C

ANISOU 2148 CA ASN B 429 4661 7322 4674 -490 -1689 -503 C

ATOM 2149 CB ASN B 429 4.911 0.478 -33.085 1.00 43.47 C

ANISOU 2149 CB ASN B 429 4569 7235 4712 -252 -1670 -326 C

ATOM 2150 CG ASN B 429 4.794 0.641 -31.557 1.00 42.88 C

ANISOU 2150 CG ASN B 429 4363 7053 4876 -193 -1534 -322 C

ATOM 2151 OD1 ASN B 429 4.994 -0.294 -30.774 1.00 42.00 O

ANISOU 2151 OD1 ASN B 429 4224 6868 4867 -321 -1425 -433 O

ATOM 2152 ND2 ASN B 429 4.489 1.865 -31.133 1.00 43.80 N

ANISOU 2152 ND2 ASN B 429 4425 7149 5068 13 -1537 -190 N

ATOM 2153 C ASN B 429 6.117 -1.831 -32.934 1.00 40.62 C

ANISOU 2153 C ASN B 429 4391 6708 4334 -590 -1479 -612 C

ATOM 2154 O ASN B 429 5.847 -2.720 -32.118 1.00 40.12 O

ANISOU 2154 O ASN B 429 4238 6603 4402 -701 -1423 -708 O

ATOM 2155 N PRO B 430 7.376 -1.594 -33.358 1.00 38.69 N

ANISOU 2155 N PRO B 430 4362 6345 3995 -554 -1365 -592 N

ATOM 2156 CA PRO B 430 8.524 -2.378 -32.884 1.00 36.44 C

ANISOU 2156 CA PRO B 430 4197 5886 3762 -622 -1177 -688 C

ATOM 2157 CB PRO B 430 9.721 -1.573 -33.388 1.00 36.11 C

ANISOU 2157 CB PRO B 430 4322 5772 3625 -531 -1078 -599 C

ATOM 2158 CG PRO B 430 9.217 -1.000 -34.683 1.00 38.86 C

ANISOU 2158 CG PRO B 430 4726 6273 3765 -501 -1232 -528 C

ATOM 2159 CD PRO B 430 7.784 -0.603 -34.373 1.00 39.49 C

ANISOU 2159 CD PRO B 430 4600 6481 3923 -451 -1407 -472 C

ATOM 2160 C PRO B 430 8.614 -2.593 -31.371 1.00 34.07 C

ANISOU 2160 C PRO B 430 3795 5462 3688 -612 -1058 -701 C

ATOM 2161 O PRO B 430 8.953 -3.700 -30.951 1.00 33.84 O

ANISOU 2161 O PRO B 430 3804 5342 3711 -716 -973 -815 O

ATOM 2162 N MSE B 431 8.323 -1.571 -30.566 1.00 32.32 N

ANISOU 2162 N MSE B 431 3467 5227 3587 -484 -1051 -588 N

ATOM 2163 CA MSE B 431 8.460 -1.693 -29.110 1.00 30.33 C

ANISOU 2163 CA MSE B 431 3144 4860 3520 -467 -933 -597 C

ATOM 2164 CB MSE B 431 8.410 -0.314 -28.423 1.00 30.13 C

ANISOU 2164 CB MSE B 431 3074 4793 3580 -299 -911 -470 C

ATOM 2165 CG MSE B 431 9.687 0.570 -28.662 1.00 28.94 C

ANISOU 2165 CG MSE B 431 3090 4524 3381 -227 -832 -394 C

ATOM 2166 SE MSE B 431 11.365 -0.168 -27.993 0.90 30.04 SE

ANISOU 2166 SE MSE B 431 3345 4495 3575 -303 -647 -469 SE

ATOM 2167 CE MSE B 431 10.912 -0.117 -26.095 1.00 24.52 C

ANISOU 2167 CE MSE B 431 2526 3717 3074 -261 -588 -475 C

ATOM 2168 C MSE B 431 7.432 -2.651 -28.519 1.00 30.68 C

ANISOU 2168 C MSE B 431 3039 4964 3655 -580 -963 -679 C

ATOM 2169 O MSE B 431 7.735 -3.405 -27.597 1.00 29.00 O

ANISOU 2169 O MSE B 431 2836 4642 3540 -644 -854 -738 O

ATOM 2170 N HIS B 432 6.223 -2.634 -29.071 1.00 32.59 N

ANISOU 2170 N HIS B 432 3139 5384 3859 -612 -1115 -677 N

ATOM 2171 CA HIS B 432 5.147 -3.532 -28.631 1.00 33.91 C

ANISOU 2171 CA HIS B 432 3137 5640 4109 -754 -1154 -751 C

ATOM 2172 CB HIS B 432 3.767 -2.933 -28.954 1.00 36.00 C

ANISOU 2172 CB HIS B 432 3166 6133 4378 -703 -1318 -688 C

ATOM 2173 CG HIS B 432 3.389 -1.817 -28.034 1.00 37.73 C

ANISOU 2173 CG HIS B 432 3252 6360 4722 -503 -1267 -573 C

ATOM 2174 ND1 HIS B 432 3.912 -0.546 -28.149 1.00 38.20 N

ANISOU 2174 ND1 HIS B 432 3408 6352 4753 -297 -1254 -461 N

ATOM 2175 CE1 HIS B 432 3.416 0.220 -27.191 1.00 39.33 C

ANISOU 2175 CE1 HIS B 432 3427 6494 5023 -146 -1198 -394 C

ATOM 2176 NE2 HIS B 432 2.611 -0.513 -26.443 1.00 40.30 N

ANISOU 2176 NE2 HIS B 432 3363 6697 5252 -246 -1161 -453 N

ATOM 2177 CD2 HIS B 432 2.578 -1.793 -26.950 1.00 40.85 C

ANISOU 2177 CD2 HIS B 432 3447 6806 5268 -481 -1207 -560 C

ATOM 2178 C HIS B 432 5.320 -4.919 -29.218 1.00 33.99 C

ANISOU 2178 C HIS B 432 3258 5618 4040 -966 -1169 -895 C

ATOM 2179 O HIS B 432 4.875 -5.903 -28.645 1.00 34.07 O

ANISOU 2179 O HIS B 432 3212 5601 4134 -1120 -1134 -973 O

ATOM 2180 N GLN B 433 5.985 -4.971 -30.363 1.00 34.16 N

ANISOU 2180 N GLN B 433 3456 5630 3893 -972 -1208 -928 N

ATOM 2181 CA GLN B 433 6.441 -6.214 -30.990 1.00 35.06 C

ANISOU 2181 CA GLN B 433 3747 5667 3907 -1135 -1189 -1076 C

ATOM 2182 CB GLN B 433 7.210 -5.810 -32.268 1.00 35.84 C

ANISOU 2182 CB GLN B 433 4029 5789 3799 -1070 -1217 -1069 C

ATOM 2183 CG GLN B 433 7.217 -6.698 -33.462 1.00 39.05 C

ANISOU 2183 CG GLN B 433 4591 6231 4014 -1213 -1290 -1208 C

ATOM 2184 CD GLN B 433 5.848 -7.071 -33.976 1.00 42.97 C

ANISOU 2184 CD GLN B 433 4958 6913 4453 -1371 -1501 -1267 C

ATOM 2185 OE1 GLN B 433 5.439 -8.218 -33.828 1.00 44.60 O

ANISOU 2185 OE1 GLN B 433 5176 7077 4694 -1566 -1513 -1404 O

ATOM 2186 NE2 GLN B 433 5.138 -6.124 -34.603 1.00 44.73 N

ANISOU 2186 NE2 GLN B 433 5063 7344 4587 -1294 -1676 -1164 N

ATOM 2187 C GLN B 433 7.344 -6.960 -29.970 1.00 32.64 C

ANISOU 2187 C GLN B 433 3545 5136 3721 -1150 -995 -1123 C

ATOM 2188 O GLN B 433 7.122 -8.135 -29.653 1.00 33.52 O

ANISOU 2188 O GLN B 433 3691 5166 3879 -1305 -963 -1228 O

ATOM 2189 N LEU B 434 8.341 -6.245 -29.452 1.00 30.05 N

ANISOU 2189 N LEU B 434 3268 4710 3441 -990 -877 -1037 N

ATOM 2190 CA LEU B 434 9.293 -6.738 -28.427 1.00 28.11 C

ANISOU 2190 CA LEU B 434 3102 4275 3305 -960 -710 -1051 C

ATOM 2191 CB LEU B 434 10.386 -5.685 -28.177 1.00 24.78 C

ANISOU 2191 CB LEU B 434 2718 3801 2896 -791 -627 -949 C

ATOM 2192 CG LEU B 434 11.320 -5.482 -29.364 1.00 25.69 C

ANISOU 2192 CG LEU B 434 2976 3925 2859 -752 -609 -959 C

ATOM 2193 CD1 LEU B 434 12.113 -4.184 -29.212 1.00 22.35 C

ANISOU 2193 CD1 LEU B 434 2551 3492 2449 -617 -559 -833 C

ATOM 2194 CD2 LEU B 434 12.245 -6.705 -29.605 1.00 21.91 C

ANISOU 2194 CD2 LEU B 434 2655 3326 2345 -797 -500 -1079 C

ATOM 2195 C LEU B 434 8.644 -7.100 -27.082 1.00 27.61 C

ANISOU 2195 C LEU B 434 2919 4169 3404 -1009 -667 -1038 C

ATOM 2196 O LEU B 434 8.945 -8.142 -26.504 1.00 27.00 O

ANISOU 2196 O LEU B 434 2924 3952 3382 -1083 -579 -1101 O

ATOM 2197 N LEU B 435 7.790 -6.207 -26.587 1.00 27.73 N

ANISOU 2197 N LEU B 435 2752 4297 3485 -949 -716 -950 N

ATOM 2198 CA LEU B 435 7.020 -6.426 -25.375 1.00 28.98 C

ANISOU 2198 CA LEU B 435 2775 4458 3779 -991 -669 -930 C

ATOM 2199 CB LEU B 435 6.102 -5.222 -25.124 1.00 28.92 C

ANISOU 2199 CB LEU B 435 2567 4606 3816 -876 -730 -833 C

ATOM 2200 CG LEU B 435 5.273 -5.249 -23.842 1.00 32.08 C

ANISOU 2200 CG LEU B 435 2806 5035 4346 -886 -657 -802 C

ATOM 2201 CD1 LEU B 435 6.159 -5.150 -22.588 1.00 31.09 C

ANISOU 2201 CD1 LEU B 435 2790 4739 4284 -805 -505 -770 C

ATOM 2202 CD2 LEU B 435 4.251 -4.124 -23.876 1.00 32.55 C

ANISOU 2202 CD2 LEU B 435 2657 5276 4437 -759 -732 -723 C

ATOM 2203 C LEU B 435 6.201 -7.743 -25.431 1.00 30.18 C

ANISOU 2203 C LEU B 435 2897 4620 3949 -1216 -695 -1029 C

ATOM 2204 O LEU B 435 6.344 -8.595 -24.548 1.00 29.89 O

ANISOU 2204 O LEU B 435 2917 4450 3988 -1295 -589 -1055 O

ATOM 2205 N ARG B 436 5.363 -7.905 -26.462 1.00 31.87 N

ANISOU 2205 N ARG B 436 3035 4987 4086 -1327 -841 -1079 N

ATOM 2206 CA ARG B 436 4.545 -9.104 -26.599 1.00 34.36 C

ANISOU 2206 CA ARG B 436 3319 5321 4414 -1575 -884 -1182 C

ATOM 2207 CB ARG B 436 3.584 -9.014 -27.800 1.00 37.45 C

ANISOU 2207 CB ARG B 436 3591 5932 4704 -1679 -1087 -1225 C

ATOM 2208 CG ARG B 436 2.381 -8.053 -27.651 1.00 42.59 C

ANISOU 2208 CG ARG B 436 3929 6839 5416 -1610 -1192 -1127 C

ATOM 2209 CD ARG B 436 1.953 -7.793 -26.187 1.00 48.03 C

ANISOU 2209 CD ARG B 436 4449 7521 6280 -1555 -1056 -1045 C

ATOM 2210 NE ARG B 436 0.516 -8.001 -26.006 1.00 55.04 N

ANISOU 2210 NE ARG B 436 5043 8622 7247 -1697 -1128 -1046 N

ATOM 2211 CZ ARG B 436 -0.097 -8.150 -24.827 1.00 58.20 C

ANISOU 2211 CZ ARG B 436 5280 9046 7789 -1739 -1005 -1006 C

ATOM 2212 NH1 ARG B 436 0.594 -8.108 -23.690 1.00 57.05 N

ANISOU 2212 NH1 ARG B 436 5256 8713 7706 -1645 -815 -964 N

ATOM 2213 NH2 ARG B 436 -1.419 -8.336 -24.784 1.00 60.68 N

ANISOU 2213 NH2 ARG B 436 5297 9587 8172 -1880 -1073 -1007 N

ATOM 2214 C ARG B 436 5.378 -10.388 -26.679 1.00 33.35 C

ANISOU 2214 C ARG B 436 3452 4963 4256 -1688 -796 -1293 C

ATOM 2215 O ARG B 436 4.996 -11.405 -26.118 1.00 33.93 O

ANISOU 2215 O ARG B 436 3548 4941 4401 -1862 -742 -1344 O

ATOM 2216 N HIS B 437 6.510 -10.333 -27.376 1.00 31.27 N

ANISOU 2216 N HIS B 437 3388 4606 3887 -1584 -771 -1325 N

ATOM 2217 CA HIS B 437 7.375 -11.493 -27.486 1.00 30.46 C

ANISOU 2217 CA HIS B 437 3535 4282 3755 -1640 -676 -1429 C

ATOM 2218 CB HIS B 437 8.585 -11.176 -28.355 1.00 29.42 C

ANISOU 2218 CB HIS B 437 3569 4112 3499 -1490 -645 -1449 C

ATOM 2219 CG HIS B 437 9.604 -12.270 -28.367 1.00 29.25 C

ANISOU 2219 CG HIS B 437 3789 3861 3463 -1483 -520 -1543 C

ATOM 2220 ND1 HIS B 437 9.469 -13.411 -29.135 1.00 30.43 N

ANISOU 2220 ND1 HIS B 437 4121 3919 3524 -1636 -540 -1701 N

ATOM 2221 CE1 HIS B 437 10.511 -14.195 -28.937 1.00 30.95 C

ANISOU 2221 CE1 HIS B 437 4388 3767 3605 -1556 -401 -1752 C

ATOM 2222 NE2 HIS B 437 11.318 -13.608 -28.068 1.00 28.06 N

ANISOU 2222 NE2 HIS B 437 3956 3372 3333 -1368 -306 -1628 N

ATOM 2223 CD2 HIS B 437 10.769 -12.407 -27.692 1.00 28.33 C

ANISOU 2223 CD2 HIS B 437 3765 3589 3411 -1332 -377 -1504 C

ATOM 2224 C HIS B 437 7.870 -11.985 -26.129 1.00 28.91 C

ANISOU 2224 C HIS B 437 3395 3896 3694 -1603 -520 -1385 C

ATOM 2225 O HIS B 437 7.863 -13.189 -25.851 1.00 29.06 O

ANISOU 2225 O HIS B 437 3551 3745 3744 -1735 -462 -1459 O

ATOM 2226 N PHE B 438 8.358 -11.040 -25.329 1.00 26.73 N

ANISOU 2226 N PHE B 438 3039 3636 3480 -1419 -459 -1264 N

ATOM 2227 CA PHE B 438 8.937 -11.304 -24.028 1.00 25.80 C

ANISOU 2227 CA PHE B 438 2974 3366 3465 -1349 -329 -1204 C

ATOM 2228 CB PHE B 438 9.963 -10.216 -23.649 1.00 23.35 C

ANISOU 2228 CB PHE B 438 2648 3063 3161 -1126 -284 -1110 C

ATOM 2229 CG PHE B 438 11.265 -10.342 -24.421 1.00 22.62 C

ANISOU 2229 CG PHE B 438 2709 2894 2992 -1025 -250 -1151 C

ATOM 2230 CD1 PHE B 438 11.950 -11.575 -24.458 1.00 24.84 C

ANISOU 2230 CD1 PHE B 438 3175 2995 3269 -1043 -173 -1228 C

ATOM 2231 CE1 PHE B 438 13.122 -11.730 -25.196 1.00 23.69 C

ANISOU 2231 CE1 PHE B 438 3151 2795 3054 -935 -123 -1274 C

ATOM 2232 CZ PHE B 438 13.623 -10.638 -25.892 1.00 23.06 C

ANISOU 2232 CZ PHE B 438 3011 2846 2905 -836 -146 -1233 C

ATOM 2233 CE2 PHE B 438 12.934 -9.427 -25.889 1.00 20.07 C

ANISOU 2233 CE2 PHE B 438 2476 2627 2525 -836 -232 -1152 C

ATOM 2234 CD2 PHE B 438 11.757 -9.288 -25.168 1.00 20.56 C

ANISOU 2234 CD2 PHE B 438 2415 2738 2659 -917 -286 -1115 C

ATOM 2235 C PHE B 438 7.911 -11.559 -22.925 1.00 27.49 C

ANISOU 2235 C PHE B 438 3066 3597 3782 -1462 -296 -1158 C

ATOM 2236 O PHE B 438 8.232 -12.211 -21.936 1.00 27.88 O

ANISOU 2236 O PHE B 438 3210 3490 3892 -1471 -192 -1132 O

ATOM 2237 N GLN B 439 6.680 -11.078 -23.096 1.00 29.49 N

ANISOU 2237 N GLN B 439 3108 4045 4051 -1546 -381 -1143 N ATOM 2238 CA GLN B 439 5.604 -11.431 -22.158 1.00 31.31 C ANISOU 2238 CA GLN B 439 3202 4318 4377 -1685 -336 -1111 C ATOM 2239 CB GLN B 439 4.397 -10.507 -22.312 1.00 31.66 C ANISOU 2239 CB GLN B 439 2958 4625 4445 -1684 -425 -1067 C ATOM 2240 CG GLN B 439 4.664 -9.127 -21.740 1.00 31.16 C ANISOU 2240 CG GLN B 439 2805 4631 4404 -1437 -393 -961 C ATOM 2241 CD GLN B 439 3.554 -8.135 -21.987 1.00 35.12 C ANISOU 2241 CD GLN B 439 3041 5378 4926 -1380 -482 -914 C ATOM 2242 OE1 GLN B 439 2.791 -8.271 -22.941 1.00 39.50 O ANISOU 2242 OE1 GLN B 439 3478 6083 5446 -1486 -616 -957 O ATOM 2243 NE2 GLN B 439 3.451 -7.121 -21.115 1.00 33.78 N ANISOU 2243 NE2 GLN B 439 2777 5251 4808 -1202 -413 -827 N ATOM 2244 C GLN B 439 5.233 -12.903 -22.334 1.00 33.82 C ANISOU 2244 C GLN B 439 3637 4511 4701 -1941 -324 -1206 C ATOM 2245 O GLN B 439 4.854 -13.575 -21.370 1.00 33.96 O ANISOU 2245 O GLN B 439 3667 4441 4794 -2059 -225 -1176 O ATOM 2246 N LYS B 440 5.402 -13.399 -23.562 1.00 35.41 N ANISOU 2246 N LYS B 440 3956 4685 4812 -2025 -415 -1321 N ATOM 2247 CA LYS B 440 5.169 -14.800 -23.882 1.00 38.51 C ANISOU 2247 CA LYS B 440 4517 4922 5193 -2267 -412 -1437 C ATOM 2248 CB LYS B 440 5.054 -14.997 -25.392 1.00 40.39 C ANISOU 2248 CB LYS B 440 4818 5225 5302 -2360 -556 -1571 C ATOM 2249 CG LYS B 440 3.714 -14.593 -25.976 1.00 42.28 C ANISOU 2249 CG LYS B 440 4794 5744 5525 -2519 -721 -1588 C ATOM 2250 CD LYS B 440 3.577 -15.162 -27.360 1.00 46.14 C ANISOU 2250 CD LYS B 440 5410 6249 5872 -2677 -861 -1746 C ATOM 2251 CE LYS B 440 3.177 -16.611 -27.299 1.00 48.55 C ANISOU 2251 CE LYS B 440 5873 6370 6205 -2981 -837 -1868 C ATOM 2252 NZ LYS B 440 3.494 -17.274 -28.574 1.00 52.80 N ANISOU 2252 NZ LYS B 440 6658 6823 6582 -3080 -924 -2045 N ATOM 2253 C LYS B 440 6.248 -15.714 -23.330 1.00 38.27 C ANISOU 2253 C LYS B 440 4773 4586 5181 -2209 -273 -1446 C ATOM 2254 O LYS B 440 5.963 -16.802 -22.818 1.00 39.92 O ANISOU 2254 O LYS B 440 5104 4621 5443 -2385 -203 -1469 O ATOM 2255 N ASP B 441 7.490 -15.259 -23.433 1.00 37.00 N ANISOU 2255 N ASP B 441 4716 4363 4979 -1961 -233 -1420 N ATOM 2256 CA ASP B 441 8.646 -16.065 -23.061 1.00 36.98 C ANISOU 2256 CA ASP B 441 4970 4096 4985 -1856 -118 -1430 C ATOM 2257 CB ASP B 441 9.051 -17.038 -24.186 1.00 39.34 C ANISOU 2257 CB ASP B 441 5510 4241 5196 -1921 -132 -1587 C ATOM 2258 CG ASP B 441 10.054 -18.065 -23.712 1.00 41.85 C ANISOU 2258 CG ASP B 441 6096 4260 5544 -1824 -5 -1598 C ATOM 2259 OD1 ASP B 441 10.678 -17.827 -22.647 1.00 45.44 O ANISOU 2259 OD1 ASP B 441 6535 4664 6067 -1657.

74. 1472 O ATOM 2260 OD2 ASP B 441 10.223 -19.107 -24.371 1.00 44.75 O ANISOU 2260 OD2 ASP B 441 6700 4440 5864 -1905.

13. 1729 O ATOM 2261 C ASP B 441 9.820 -15.187 -22.699 1.00 33.68 C ANISOU 2261 C ASP B 441 4532 3698 4566 -1573 -72 -1339 C ATOM 2262 O ASP B 441 10.467 -14.624 -23.570 1.00 33.22 O ANISOU 2262 O ASP B 441 4476 3713 4433 -1450 -108 -1370 O ATOM 2263 N ALA B 442 10.076 -15.111 -21.398 1.00 31.93 N ANISOU 2263 N ALA B 442 4298 3412 4421 -1490.

9. 1227 N ATOM 2264 CA ALA B 442 11.092 -14.273 -20.794 1.00 29.34 C ANISOU 2264 CA ALA B 442 3931 3110 4105 -1256.

44. 1131 C ATOM 2265 CB ALA B 442 10.565 -13.725 -19.499 1.00 28.01 C ANISOU 2265 CB ALA B 442 3635 3010 3996 -1252.

75. 1017 C ATOM 2266 C ALA B 442 12.362 -15.072 -20.530 1.00 29.14 C ANISOU 2266 C ALA B 442 4112 2874 4085 -1118 122 -1131 C ATOM 2267 O ALA B 442 13.360 -14.523 -20.065 1.00 28.18 O ANISOU 2267 O ALA B 442 3967 2766 3973 -928 144 -1060 O ATOM 2268 N LYS B 443 12.312 -16.375 -20.791 1.00 30.53 N ANISOU 2268 N LYS B 443 4490 2851 4260 -1214 161 -1209 N ATOM 2269 CA LYS B 443 13.417 -17.281 -20.437 1.00 30.65 C ANISOU 2269 CA LYS B 443 4716 2636 4292 -1068 243 -1199 C ATOM 2270 CB LYS B 443 13.107 -18.727 -20.819 1.00 32.70 C ANISOU 2270 CB LYS B 443 5223 2653 4549 -1211 284 -1301 C ATOM 2271 CG LYS B 443 12.149 -19.457 -19.915 1.00 34.47 C ANISOU 2271 CG LYS B 443 5515 2754 4829 -1415 319 -1250 C ATOM 2272 CD LYS B 443 11.797 -20.833 -20.531 1.00 39.27 C ANISOU 2272 CD LYS B 443 6384 3113 5426 -1597 346 -1379 C ATOM 2273 CE LYS B 443 10.531 -21.410 -19.929 1.00 42.83 C ANISOU 2273 CE LYS B 443 6847 3503 5925 -1897 362 -1351 C ATOM 2274 NZ LYS B 443 9.967 -22.468 -20.802 1.00 49.83 N ANISOU 2274 NZ LYS B 443 7928 4218 6787 -2143 348 -1509 N ATOM 2275 C LYS B 443 14.752 -16.877 -21.049 1.00 29.07 C ANISOU 2275 C LYS B 443 4516 2473 4056 -835 255 -1220 C ATOM 2276 O LYS B 443 15.765 -16.817 -20.355 1.00 28.19 O ANISOU 2276 O LYS B 443 4414 2317 3978 -643 293 -1137 O ATOM 2277 N VAL B 444 14.760 -16.582 -22.341 1.00 28.47 N ANISOU 2277 N VAL B 444 4419 2495 3904 -857 219 -1324 N ATOM 2278 CA VAL B 444 15.989 -16.171 -23.001 1.00 27.62 C ANISOU 2278 CA VAL B 444 4298 2443 3753 -657 251 -1342 C ATOM 2279 CB VAL B 444 15.844 -16.164 -24.546 1.00 29.10 C ANISOU 2279 CB VAL B 444 4535 2697 3822 -721 229 -1480 C ATOM 2280 CG1 VAL B 444 17.165 -15.772 -25.210 1.00 27.34 C ANISOU 2280 CG1 VAL B 444 4300 2538 3551 -514 294 -1491 C ATOM 2281 CG2 VAL B 444 15.361 -17.547 -25.079 1.00 29.33 C ANISOU 2281 CG2 VAL B 444 4809 2521 3814 -859 251 -1625 C ATOM 2282 C VAL B 444 16.469 -14.798 -22.492 1.00 26.53 C ANISOU 2282 C VAL B 444 3944 2494 3640 -540 221 -1220 C ATOM 2283 O VAL B 444 17.678 -14.605 -22.233 1.00 26.44 O ANISOU 2283 O VAL B 444 3908 2485 3653 -353 265 -1171 O ATOM 2284 N LEU B 445 15.527 -13.866 -22.343 1.00 24.58 N ANISOU 2284 N LEU B 445 3544 2404 3392 -651 144 -1177 N ATOM 2285 CA LEU B 445 15.783 -12.541 -21.821 1.00 23.69 C ANISOU 2285 CA LEU B 445 3257 2443 3302 -569 112 -1072 C ATOM 2286 CB LEU B 445 14.471 -11.724 -21.792 1.00 22.83 C ANISOU 2286 CB LEU B 445 3011 2476 3188 -699.

34. 1048 C ATOM 2287 CG LEU B 445 14.528 -10.302 -21.202 1.00 20.40 C ANISOU 2287 CG LEU B 445 2549 2300 2903 -624 1 -949 C ATOM 2288 CD1 LEU B 445 15.452 -9.445 -22.022 1.00 20.80 C ANISOU 2288 CD1 LEU B 445 2565 2433 2905 -525 -8 -942 C ATOM 2289 CD2 LEU B 445 13.139 -9.660 -21.107 1.00 21.01 C ANISOU 2289 CD2 LEU B 445 2499 2498 2987 -724 -59 -929 C ATOM 2290 C LEU B 445 16.386 -12.568 -20.405 1.00 23.63 C ANISOU 2290 C LEU B 445 3244 2369 3367 -464 143 -970 C ATOM 2291 O LEU B 445 17.378 -11.894 -20.145 1.00 23.04 O ANISOU 2291 O LEU B 445 3098 2354 3304 -332 144 -914 O ATOM 2292 N PHE B 446 15.749 -13.322 -19.503 1.00 24.55 N ANISOU 2292 N PHE B 446 3434 2372 3522 -540 163 -944 N ATOM 2293 CA PHE B 446 16.165 -13.405 -18.103 1.00 24.13 C ANISOU 2293 CA PHE B 446 3400 2257 3510 -456 185 -840 C ATOM 2294 CB PHE B 446 15.065 -14.052 -17.240 1.00 24.76 C ANISOU 2294 CB PHE B 446 3545 2251 3610 -600 213 -806 C ATOM 2295 CG PHE B 446 13.941 -13.121 -16.834 1.00 24.29 C ANISOU 2295 CG PHE B 446 3329 2348 3552 -706 187 -774 C ATOM 2296 CD1 PHE B 446 13.834 -11.833 -17.342 1.00 23.90 C ANISOU 2296 CD1 PHE B 446 3118 2476 3486 -675 130 -782 C ATOM 2297 CE1 PHE B 446 12.781 -10.995 -16.975 1.00 24.51 C ANISOU 2297 CE1 PHE B 446 3058 2686 3570 -740 113 -754 C ATOM 2298 CZ PHE B 446 11.834 -11.441 -16.088 1.00 25.45 C ANISOU 2298 CZ PHE B 446 3177 2782 3710 -847 166 -718 C ATOM 2299 CE2 PHE B 446 11.922 -12.724 -15.582 1.00 26.97 C ANISOU 2299 CE2 PHE B 446 3531 2804 3914 -908 228 -704 C ATOM 2300 CD2 PHE B 446 12.973 -13.555 -15.954 1.00 26.27 C ANISOU 2300 CD2 PHE B 446 3601 2560 3821 -831 232 -730 C ATOM 2301 C PHE B 446 17.483 -14.179 -17.956 1.00 24.88 C ANISOU 2301 C PHE B 446 3609 2223 3621 -283 225 -826 C ATOM 2302 O PHE B 446 18.356 -13.744 -17.220 1.00 24.61 O ANISOU 2302 O PHE B 446 3518 2231 3603 -148 207 -746 O ATOM 2303 N GLN B 447 17.622 -15.313 -18.650 1.00 26.27 N ANISOU 2303 N GLN B 447 3944 2245 3792 -281 275 -907 N ATOM 2304 CA GLN B 447 18.836 -16.149 -18.568 1.00 27.60 C ANISOU 2304 CA GLN B 447 4228 2275 3983 -85 326 -899 C ATOM 2305 CB GLN B 447 18.612 -17.566 -19.132 1.00 29.38 C ANISOU 2305 CB GLN B 447 4694 2267 4204 -123 392 -993 C ATOM 2306 CG GLN B 447 17.510 -18.396 -18.464 1.00 30.32 C ANISOU 2306 CG GLN B 447 4963 2215 4340 -306 406 -972 C ATOM 2307 CD GLN B 447 17.823 -18.852 -17.033 1.00 33.13 C ANISOU 2307 CD GLN B 447 5407 2450 4733 -211 422 -829 C ATOM 2308 OE1 GLN B 447 18.625 -18.249 -16.326 1.00 34.35 O ANISOU 2308 OE1 GLN B 447 5450 2708 4895 -47 387 -731 O ATOM 2309 NE2 GLN B 447 17.167 -19.921 -16.603 1.00 33.37 N ANISOU 2309 NE2 GLN B 447 5644 2258 4776 -332 469 -814 N ATOM 2310 C GLN B 447 20.092 -15.516 -19.196 1.00 27.69 C ANISOU 2310 C GLN B 447 4114 2418 3988 88 332 -910 C ATOM 2311 O GLN B 447 21.206 -15.860 -18.819 1.00 28.70 O ANISOU 2311 O GLN B 447 4248 2505 4150 282 355 -863 O ATOM 2312 N ASN B 448 19.912 -14.574 -20.117 1.00 28.11 N ANISOU 2312 N ASN B 448 4044 2639 3997 20 310 -961 N ATOM 2313 CA ASN B 448 21.036 -13.924 -20.791 1.00 28.81 C ANISOU 2313 CA ASN B 448 4012 2863 4073 147 333 -967 C ATOM 2314 CB ASN B 448 20.855 -13.960 -22.313 1.00 30.00 C ANISOU 2314 CB ASN B 448 4206 3050 4141 92 375 -1087 C ATOM 2315 CG ASN B 448 21.087 -15.348 -22.884 1.00 33.62 C ANISOU 2315 CG ASN B 448 4871 3323 4581 157 462 -1194 C ATOM 2316 OD1 ASN B 448 22.214 -15.833 -22.902 1.00 36.46 O ANISOU 2316 OD1 ASN B 448 5249 3635 4969 354 538 -1194 O ATOM 2317 ND2 ASN B 448 20.022 -16.002 -23.324 1.00 35.23 N ANISOU 2317 ND2 ASN B 448 5229 3417 4739 -5 449 -1287 N ATOM 2318 C ASN B 448 21.345 -12.521 -20.310 1.00 27.59 C ANISOU 2318 C ASN B 448 3659 2892 3933 147 269 -877 C ATOM 2319 O ASN B 448 22.364 -11.957 -20.700 1.00 28.46 O ANISOU 2319 O ASN B 448 3654 3115 4046 238 290 -863 O ATOM 2320 N TRP B 449 20.496 -11.979 -19.431 1.00 27.14 N ANISOU 2320 N TRP B 449 3567 2857 3886 45 203 -819 N ATOM 2321 CA TRP B 449 20.598 -10.569 -18.976 1.00 25.11 C ANISOU 2321 CA TRP B 449 3159 2749 3634 23 140 -751 C ATOM 2322 CB TRP B 449 19.384 -10.193 -18.115 1.00 23.06 C ANISOU 2322 CB TRP B 449 2904 2486 3374 -89.

95. 715 C ATOM 2323 CG TRP B 449 19.356 -8.762 -17.660 1.00 22.27 C ANISOU 2323 CG TRP B 449 2686 2504 3269 -109.

39. 663 C ATOM 2324 CD1 TRP B 449 19.742 -8.290 -16.438 1.00 20.41 C ANISOU 2324 CD1 TRP B 449 2424 2285 3047 -68 -1 -596 C ATOM 2325 NE1 TRP B 449 19.559 -6.921 -16.377 1.00 20.85 N ANISOU 2325 NE1 TRP B 449 2400 2431 3090 -109 -42 -580 N ATOM 2326 CE2 TRP B 449 19.051 -6.475 -17.580 1.00 20.31 C ANISOU 2326 CE2 TRP B 449 2300 2412 3004 -163 -32 -620 C ATOM 2327 CD2 TRP B 449 18.911 -7.599 -18.423 1.00 20.86 C ANISOU 2327 CD2 TRP B 449 2430 2431 3064 -171.

12. 676 C ATOM 2328 CE3 TRP B 449 18.388 -7.415 -19.723 1.00 22.46 C ANISOU 2328 CE3 TRP B 449 2627 2683 3225 -229.

16. 727 C ATOM 2329 CZ3 TRP B 449 18.032 -6.099 -20.146 1.00 19.45 C ANISOU 2329 CZ3 TRP B 449 2176 2397 2819 -261 -26 -701 C ATOM 2330 CH2 TRP B 449 18.184 -5.005 -19.271 1.00 20.17 C ANISOU 2330 CH2 TRP B 449 2218 2512 2935 -242 -59 -641 C ATOM 2331 CZ2 TRP B 449 18.683 -5.166 -17.992 1.00 19.60 C ANISOU 2331 CZ2 TRP B 449 2154 2396 2896 -202 -64 -609 C ATOM 2332 C TRP B 449 21.897 -10.183 -18.247 1.00 25.56 C ANISOU 2332 C TRP B 449 3119 2864 3729 148 117 -678 C ATOM 2333 O TRP B 449 22.382 -9.027 -18.344 1.00 25.79 O ANISOU 2333 O TRP B 449 3020 3020 3758 13.

84. 649 O ATOM 2334 N GLY B 450 22.478 -11.120 -17.510 1.00 25.38 N ANISOU 2334 N GLY B 450 3157 2749 3739 265 124 -642 N ATOM 2335 CA GLY B 450 23.632 -10.745 -16.694 1.00 23.99 C ANISOU 2335 CA GLY B 450 2870 2652 3595 37.

71. 565 C ATOM 2336 C GLY B 450 23.294 -10.879 -15.215 1.00 22.88 C ANISOU 2336 C GLY B 450 2794 2456 3443 37.

4. 488 C ATOM 2337 O GLY B 450 22.203 -10.500 -14.778 1.00 21.96 O ANISOU 2337 O GLY B 450 2726 2323 3294 250 -485 O ATOM 2338 N ILE B 451 24.230 -11.444 -14.467 1.00 23.43 N ANISOU 2338 N ILE B 451 2862 2506 3532 521 -32 -423 N ATOM 2339 CA ILE B 451 24.085 -11.705 -13.026 1.00 23.62 C ANISOU 2339 CA ILE B 451 2972 2480 3523 547 -99 -335 C ATOM 2340 CB ILE B 451 24.108 -13.262 -12.731 1.00 25.59 C ANISOU 2340 CB ILE B 451 3405 2536 3781 668 -54 -296 C ATOM 2341 CG1 ILE B 451 23.397 -13.628 -11.415 1.00 23.95 C ANISOU 2341 CG1 ILE B 451 3355 2232 3512 625 -81 -211 C ATOM 2342 CD1 ILE B 451 21.902 -13.753 -11.539 1.00 21.00 C ANISOU 2342 CD1 ILE B 451 3094 1771 3115 435 -5 -253 C ATOM 2343 CG2 ILE B 451 25.512 -13.822 -12.743 1.00 26.15 C ANISOU 2343 CG2 ILE B 451 3411 2625 3899 895 -78 -254 C ATOM 2344 C ILE B 451 25.203 -10.957 -12.295 1.00 23.68 C ANISOU 2344 C ILE B 451 2829 2639 3529 616 -211 -274 C ATOM 2345 O ILE B 451 26.284 -10.721 -12.867 1.00 24.64 O ANISOU 2345 O ILE B 451 2790 2871 3701 694 -221 -284 O ATOM 2346 N GLU B 452 24.948 -10.545 -11.062 1.00 22.87 N ANISOU 2346 N GLU B 452 2770 2558 3363 573 -294 -217 N ATOM 2347 CA GLU B 452 25.953 -9.818 -10.284 1.00 23.14 C ANISOU 2347 CA GLU B 452 2678 2738 3377 610 -425 -170 C ATOM 2348 CB GLU B 452 25.784 -8.289 -10.406 1.00 22.01 C ANISOU 2348 CB GLU B 452 2434 2709 3218 450 -462 -223 C ATOM 2349 CG GLU B 452 24.512 -7.724 -9.739 1.00 20.85 C ANISOU 2349 CG GLU B 452 2420 2510 2993 324 -449 -239 C ATOM 2350 CD GLU B 452 24.217 -6.272 -10.076 1.00 22.01 C ANISOU 2350 CD GLU B 452 2499 2725 3137 190 -457 -300 C ATOM 2351 OE1 GLU B 452 25.104 -5.613 -10.663 1.00 27.18 O ANISOU 2351 OE1 GLU B 452 3010 3475 3841 169 -493 -317 O ATOM 2352 OE2 GLU B 452 23.097 -5.773 -9.748 1.00 23.75 O ANISOU 2352 OE2 GLU B 452 2812 2904 3310 108 -421 -326 O ATOM 2353 C GLU B 452 25.850 -10.194 -8.828 1.00 24.13 C ANISOU 2353 C GLU B 452 2934 2823 3413 655 -507 -83 C ATOM 2354 O GLU B 452 24.765 -10.560 -8.354 1.00 23.91 O ANISOU 2354 O GLU B 452 3081 2678 3325 593 -450 -69 O ATOM 2355 N AHIS B 453 26.975 -10.085 -8.119 0.50 25.47 N ANISOU 2355 N AHIS B 453 3010 3104 3564 753 -642 -21 N ATOM 2356 N BHIS B 453 26.985 -10.127 -8.136 0.50 25.61 N ANISOU 2356 N BHIS B 453 3029 3119 3584 758 -640 -20 N ATOM 2357 CA AHIS B 453 27.020 -10.189 -6.668 0.50 26.91 C ANISOU 2357 CA AHIS B 453 3303 3295 3629 785 -756 64 C ATOM 2358 CA BHIS B 453 27.023 -10.168 -6.690 0.50 27.08 C ANISOU 2358 CA BHIS B 453 3319 3317 3651 783 -755 61 C ATOM 2359 CB AHIS B 453 28.450 -10.463 -6.189 0.50 28.79 C ANISOU 2359 CB AHIS B 453 3408 3656 3874 952 -909 143 C ATOM 2360 CB BHIS B 453 28.476 -10.182 -6.188 0.50 29.00 C ANISOU 2360 CB BHIS B 453 3408 3713 3899 919 -922 129 C ATOM 2361 CG AHIS B 453 28.526 -10.925 -4.767 0.50 30.03 C ANISOU 2361 CG AHIS B 453 3716 3797 3897 1033 -1027 254 C ATOM 2362 CG BHIS B 453 29.316 -11.302 -6.740 0.50 30.90 C ANISOU 2362 CG BHIS B 453 3578 3926 4237 1140 -898 180 C ATOM 2363 ND1AHIS B 453 29.035 -10.142 -3.753 0.50 30.65 N ANISOU 2363 ND1AHIS B 453 3748 4029 3869 987 -1204 274 N ATOM 2364 ND1BHIS B 453 29.448 -12.521 -6.107 0.50 32.82 N ANISOU 2364 ND1BHIS B 453 3973 4053 4444 1327 -921 290 N ATOM 2365 CE1AHIS B 453 28.956 -10.802 -2.613 0.50 31.81 C ANISOU 2365 CE1AHIS B 453 4076 4127 3883 1080 -1278 384 C ATOM 2366 CE1BHIS B 453 30.259 -13.295 -6.810 0.50 33.79 C ANISOU 2366 CE1BHIS B 453 3997 4166 4676 1525 -885 307 C ATOM 2367 NE2AHIS B 453 28.403 -11.980 -2.849 0.50 31.22 N ANISOU 2367 NE2AHIS B 453 4168 3857 3836 1177 -1145 441 N ATOM 2368 NE2BHIS B 453 30.665 -12.623 -7.871 0.50 32.37 N ANISOU 2368 NE2BHIS B 453 3598 4108 4594 1462 -832 212 N ATOM 2369 CD2AHIS B 453 28.125 -12.081 -4.187 0.50 29.97 C ANISOU 2369 CD2AHIS B 453 3930 3629 3828 1144 -992 352 C ATOM 2370 CD2BHIS B 453 30.092 -11.374 -7.852 0.50 31.63 C ANISOU 2370 CD2BHIS B 453 3473 4089 4457 1217 -845 138 C ATOM 2371 C AHIS B 453 26.479 -8.902 -6.033 0.50 26.48 C ANISOU 2371 C AHIS B 453 3268 3310 3482 609 -804 15 C ATOM 2372 C BHIS B 453 26.269 -8.928 -6.168 0.50 26.24 C ANISOU 2372 C BHIS B 453 3253 3258 3458 595 -774 5 C ATOM 2373 O AHIS B 453 26.801 -7.795 -6.474 0.50 26.15 O ANISOU 2373 O AHIS B 453 3082 3376 3477 510 -837 -54 O ATOM 2374 O BHIS B 453 26.205 -7.888 -6.829 0.50 25.07 O ANISOU 2374 O BHIS B 453 2993 3176 3357 478 -757 -78 O ATOM 2375 N ILE B 454 25.653 -9.052 -5.003 1.00 27.27 N ANISOU 2375 N ILE B 454 3565 3340 3458 574 -794 52 N ATOM 2376 CA ILE B 454 24.998 -7.895 -4.372 1.00 27.11 C ANISOU 2376 CA ILE B 454 3599 3362 3338 428 -809 -5 C ATOM 2377 CB ILE B 454 23.458 -7.972 -4.438 1.00 26.13 C ANISOU 2377 CB ILE B 454 3614 3124 3189 336 -643 -36 C ATOM 2378 CG1 ILE B 454 22.894 -9.039 -3.497 1.00 26.52 C ANISOU 2378 CG1 ILE B 454 3869 3071 3135 383 -593 61 C ATOM 2379 CD1 ILE B 454 21.346 -8.995 -3.430 1.00 25.42 C ANISOU 2379 CD1 ILE B 454 3835 2857 2966 266 -427 30 C ATOM 2380 CG2 ILE B 454 22.973 -8.138 -5.878 1.00 24.81 C ANISOU 2380 CG2 ILE B 454 3361 2901 3162 300 -521 -96 C ATOM 2381 C ILE B 454 25.494 -7.622 -2.952 1.00 29.39 C ANISOU 2381 C ILE B 454 3966 3732 3468 447 -963 45 C ATOM 2382 O ILE B 454 26.002 -8.522 -2.286 1.00 30.77 O ANISOU 2382 O ILE B 454 4208 3900 3584 574 -1039 150 O ATOM 2383 N ASP B 455 25.404 -6.364 -2.524 1.00 30.94 N ANISOU 2383 N ASP B 455 4162 4002 3593 326 -1021 -33 N ATOM 2384 CA ASP B 455 25.620 -6.005 -1.121 1.00 33.96 C ANISOU 2384 CA ASP B 455 4670 4448 3787 311 -1152 -13 C ATOM 2385 CB ASP B 455 25.973 -4.520 -0.989 1.00 35.01 C ANISOU 2385 CB ASP B 455 4741 4672 3890 174 -1250 -124 C ATOM 2386 CG ASP B 455 27.250 -4.149 -1.740 1.00 38.55 C ANISOU 2386 CG ASP B 455 4937 5236 4473 156 -1370 -141 C ATOM 2387 OD1 ASP B 455 28.218 -4.942 -1.722 1.00 41.76 O ANISOU 2387 OD1 ASP B 455 5228 5723 4918 276 -1471 -55 O ATOM 2388 OD2 ASP B 455 27.285 -3.060 -2.363 1.00 42.88 O ANISOU 2388 OD2 ASP B 455 5401 5798 509.

27. 1354 -234 O ATOM 2389 C ASP B 455 24.357 -6.303 -0.319 1.00 33.96 C ANISOU 2389 C ASP B 455 4908 4349 3646 293 -1024 10 C ATOM 2390 O ASP B 455 23.262 -6.210 -0.836 1.00 32.87 O ANISOU 2390 O ASP B 455 4798 4127 3563 235 -851 -36 O ATOM 2391 N ASN B 456 24.516 -6.670 0.945 1.00 36.21 N ANISOU 2391 N ASN B 456 5355 4657 3744 343 -1109 87 N ATOM 2392 CA ASN B 456 23.386 -6.753 1.864 1.00 36.87 C ANISOU 2392 CA ASN B 456 5670 4678 3659 306 -986 102 C ATOM 2393 CB ASN B 456 23.798 -7.463 3.160 1.00 39.34 C ANISOU 2393 CB ASN B 456 6165 5017 3764 394 -1096 229 C ATOM 2394 CG ASN B 456 24.239 -8.874 2.934 1.00 41.30 C ANISOU 2394 CG ASN B 456 6415 5195 4082 538 -1111 377 C ATOM 2395 OD1 ASN B 456 23.568 -9.643 2.250 1.00 44.21 O ANISOU 2395 OD1 ASN B 456 6797 5430 4570 545 -942 407 O ATOM 2396 ND2 ASN B 456 25.373 -9.238 3.516 1.00 45.13 N ANISOU 2396 ND2 ASN B 456 6893 5765 4491 658 -1320 471 N ATOM 2397 C ASN B 456 22.849 -5.350 2.191 1.00 35.93 C ANISOU 2397 C ASN B 456 5597 4597 3458 185 -957 -37 C ATOM 2398 O ASN B 456 23.527 -4.564 2.854 1.00 36.85 O ANISOU 2398 O ASN B 456 5741 4804 3458 149 -1118 -88 O ATOM 2399 N VAL B 457 21.652 -5.044 1.700 1.00 34.16 N ANISOU 2399 N VAL B 457 5380 4302 3299 127 -759 -100 N ATOM 2400 CA VAL B 457 20.941 -3.805 2.045 1.00 33.91 C ANISOU 2400 CA VAL B 457 5421 4277 318.

49. 691 -223 C ATOM 2401 CB VAL B 457 20.748 -2.905 0.801 1.00 32.48 C ANISOU 2401 CB VAL B 457 5070 4073 3197 -6 -646 -327 C ATOM 2402 CG1 VAL B 457 20.040 -1.606 1.166 1.00 32.79 C ANISOU 2402 CG1 VAL B 457 5203 4095 3159 -56 -577 -451 C ATOM 2403 CG2 VAL B 457 22.108 -2.600 0.143 1.00 33.09 C ANISOU 2403 CG2 VAL B 457 4980 4206 3385 -23 -828 -340 C ATOM 2404 C VAL B 457 19.575 -4.186 2.625 1.00 33.78 C ANISOU 2404 C VAL B 457 5553 4211 307.

49. 478 -196 C ATOM 2405 O VAL B 457 18.791 -4.831 1.940 1.00 32.79 O ANISOU 2405 O VAL B 457 5360 4029 306.

45. 328 -158 O ATOM 2406 N MSE B 458 19.303 -3.798 3.876 1.00 34.81 N ANISOU 2406 N MSE B 458 5882 4374 297.

43. 464 -218 N ATOM 2407 CA MSE B 458 18.039 -4.135 4.545 1.00 35.03 C ANISOU 2407 CA MSE B 458 6051 4379 287.

40. 244 -187 C ATOM 2408 CB MSE B 458 18.056 -3.708 6.020 1.00 37.27 C ANISOU 2408 CB MSE B 458 6581 4716 286.

45. 267 -210 C ATOM 2409 CG MSE B 458 16.872 -4.222 6.828 1.00 37.38 C ANISOU 2409 CG MSE B 458 6752 4723 2726.

45. 30 -149 C ATOM 2410 SE MSE B 458 16.820 -3.511 8.603 0.90 41.33 SE ANISOU 2410 SE MSE B 458 7579 5297 282.

55. 30 -211 SE ATOM 2411 CE MSE B 458 15.420 -4.680 9.317 1.00 44.38 C ANISOU 2411 CE MSE B 458 8103 5675 3084 45 298 -58 C ATOM 2412 C MSE B 458 16.868 -3.480 3.818 1.00 33.79 C ANISOU 2412 C MSE B 458 5784 4197 285.

10. 53 -282 C ATOM 2413 O MSE B 458 16.995 -2.362 3.336 1.00 32.16 O ANISOU 2413 O MSE B 458 5505 3991 2722 -1 -98 -401 O ATOM 2414 N GLY B 459 15.744 -4.194 3.715 1.00 34.01 N ANISOU 2414 N GLY B 459 5796 4205 2922 -6 153 -221 N ATOM 2415 CA GLY B 459 14.570 -3.680 2.991 1.00 33.33 C ANISOU 2415 CA GLY B 459 5569 4123 2974 -25 328 -296 C ATOM 2416 C GLY B 459 14.548 -4.009 1.501 1.00 31.85 C ANISOU 2416 C GLY B 459 5161 3902 3041 -49 307 -289 C ATOM 2417 O GLY B 459 13.682 -3.523 0.781 1.00 30.68 O ANISOU 2417 O GLY B 459 4875 3768 3012 -57 409 -348 O ATOM 2418 N MSE B 460 15.478 -4.860 1.057 1.00 31.24 N ANISOU 2418 N MSE B 460 5054 3784 3033 -50 177 -214 N ATOM 2419 CA MSE B 460 15.677 -5.150 -0.354 1.00 31.07 C ANISOU 2419 CA MSE B 460 4850 3729 3225 -65 137 -221 C ATOM 2420 CB MSE B 460 16.629 -4.100 -0.868 1.00 30.09 C ANISOU 2420 CB MSE B 460 4650 3629 3156 -42 -303 C ATOM 2421 CG MSE B 460 16.615 -3.833 -2.309 1.00 32.45 C ANISOU 2421 CG MSE B 460 4767 3917 3643 -59 -347 C ATOM 2422 SE MSE B 460 17.913 -2.375 -2.609 0.90 34.00 SE ANISOU 2422 SE MSE B 460 4919 4140 3859 -59 -219 -436 SE ATOM 2423 CE MSE B 460 16.991 -0.929 -1.707 1.00 33.99 C ANISOU 2423 CE MSE B 460 5050 4135 3729 -54 -133 -542 C ATOM 2424 C MSE B 460 16.331 -6.512 -0.539 1.00 28.84 C ANISOU 2424 C MSE B 460 4594 3383 2980 -52.

79. 112 C ATOM 2425 O MSE B 460 17.138 -6.910 0.282 1.00 30.15 O ANISOU 2425 O MSE B 460 4884 3544 3026 -3 -19 -42 O ATOM 2426 N VAL B 461 16.008 -7.206 -1.624 1.00 27.09 N ANISOU 2426 N VAL B 461 4265 3111 2918 -87 131 -100 N ATOM 2427 CA VAL B 461 16.671 -8.480 -1.957 1.00 26.80 C ANISOU 2427 CA VAL B 461 4263 2984 2937 -58.

81. 14 C ATOM 2428 CB VAL B 461 15.830 -9.766 -1.561 1.00 27.65 C ANISOU 2428 CB VAL B 461 4497 2994 3014 -121 226 84 C ATOM 2429 CG1 VAL B 461 15.820 -9.957 -0.084 1.00 30.27 C ANISOU 2429 CG1 VAL B 461 5027 3330 3145 -99 248 174 C ATOM 2430 CG2 VAL B 461 14.394 -9.726 -2.097 1.00 27.50 C ANISOU 2430 CG2 VAL B 461 4380 2992 3077 -246 392 36 C ATOM 2431 C VAL B 461 17.010 -8.528 -3.436 1.00 24.89 C ANISOU 2431 C VAL B 461 3858 2724 2874 -57.

39. 71 C ATOM 2432 O VAL B 461 16.458 -7.760 -4.216 1.00 22.95 O ANISOU 2432 O VAL B 461 3485 2528 2709 -103.

75. 156 O ATOM 2433 N GLY B 462 17.912 -9.440 -3.809 1.00 24.45 N ANISOU 2433 N GLY B 462 3821 2599 287.

11. 31 -19 N ATOM 2434 CA GLY B 462 18.142 -9.764 -5.208 1.00 23.12 C ANISOU 2434 CA GLY B 462 3536 2394 285.

12. 34 -67 C ATOM 2435 C GLY B 462 17.109 -10.760 -5.728 1.00 23.17 C ANISOU 2435 C GLY B 462 3586 2297 2922 -82.

97. 61 C ATOM 2436 O GLY B 462 16.340 -11.359 -4.962 1.00 23.84 O ANISOU 2436 O GLY B 462 3793 2324 2942 -146 191 2 O ATOM 2437 N VAL B 463 17.080 -10.925 -7.043 1.00 22.89 N ANISOU 2437 N VAL B 463 3453 2241 3003 -108 105 -129 N ATOM 2438 CA VAL B 463 16.154 -11.866 -7.677 1.00 23.22 C ANISOU 2438 CA VAL B 463 3530 2185 3106 -220 206 -145 C ATOM 2439 CB VAL B 463 14.824 -11.131 -8.120 1.00 22.55 C ANISOU 2439 CB VAL B 463 3313 2204 3052 -353 274 -216 C ATOM 2440 CG1 VAL B 463 15.089 -10.058 -9.145 1.00 20.58 C ANISOU 2440 CG1 VAL B 463 2902 2062 2857 -321 205 -302 C ATOM 2441 CG2 VAL B 463 13.796 -12.107 -8.634 1.00 23.79 C ANISOU 2441 CG2 VAL B 463 3493 2283 3263 -503 366 -230 C ATOM 2442 C VAL B 463 16.893 -12.591 -8.810 1.00 22.85 C ANISOU 2442 C VAL B 463 3485 2051 3146 -163 174 -184 C ATOM 2443 O VAL B 463 17.576 -11.960 -9.618 1.00 21.88 O ANISOU 2443 O VAL B 463 3242 2006 3066 -101 110 -243 O ATOM 2444 N LEU B 464 16.772 -13.917 -8.835 1.00 24.48 N ANISOU 2444 N LEU B 464 3847 2086 3370 -184 230 -147 N ATOM 2445 CA LEU B 464 17.398 -14.757 -9.860 1.00 24.70 C ANISOU 2445 CA LEU B 464 3920 1996 3469 -121 225 -193 C ATOM 2446 CB LEU B 464 17.692 -16.167 -9.278 1.00 26.50 C ANISOU 2446 CB LEU B 464 4383 2003 3684 -60 262 -101 C ATOM 2447 CG LEU B 464 18.614 -16.282 -8.045 1.00 27.20 C ANISOU 2447 CG LEU B 464 4556 2079 3698 112 196 31 C ATOM 2448 CD1 LEU B 464 18.909 -17.751 -7.716 1.00 26.95 C ANISOU 2448 CD1 LEU B 464 4774 1800 3666 194 234 122 C ATOM 2449 CD2 LEU B 464 19.925 -15.482 -8.186 1.00 25.91 C ANISOU 2449 CD2 LEU B 464 4231 2069 3545 291 74 17 C ATOM 2450 C LEU B 464 16.470 -14.848 -11.075 1.00 24.29 C ANISOU 2450 C LEU B 464 3811 1943 3475 -279 275 -305 C ATOM 2451 O LEU B 464 15.296 -14.566 -10.935 1.00 23.51 O ANISOU 2451 O LEU B 464 3661 1902 3369 -438 321 -317 O ATOM 2452 N PRO B 465 16.996 -15.222 -12.270 1.00 25.25 N ANISOU 2452 N PRO B 465 3932 2015 3645 -232 265 -388 N ATOM 2453 CA PRO B 465 16.120 -15.432 -13.438 1.00 25.68 C ANISOU 2453 CA PRO B 465 3964 2062 3731 -391 297 -499 C ATOM 2454 CB PRO B 465 17.050 -16.084 -14.460 1.00 25.85 C ANISOU 2454 CB PRO B 465 4061 1984 3778 -277 298 -570 C ATOM 2455 CG PRO B 465 18.388 -15.510 -14.133 1.00 24.55 C ANISOU 2455 CG PRO B 465 3812 1904 3610 -63 245 -516 C ATOM 2456 CD PRO B 465 18.421 -15.441 -12.622 1.00 25.27 C ANISOU 2456 CD PRO B 465 3945 1989 3669 -26 225 -389 C ATOM 2457 C PRO B 465 14.846 -16.281 -13.209 1.00 28.21 C ANISOU 2457 C PRO B 465 4391 2269 4059 -603 369 -498 C ATOM 2458 O PRO B 465 13.803 -15.960 -13.790 1.00 27.91 O ANISOU 2458 O PRO B 465 4244 2328 4033 -771 372 -565 O ATOM 2459 N ASP B 466 14.925 -17.337 -12.388 1.00 30.80 N ANISOU 2459 N ASP B 466 4922 2403 4379 -599 424 -415 N ATOM 2460 CA ASP B 466 13.752 -18.159 -12.058 1.00 33.52 C ANISOU 2460 CA ASP B 466 5376 2631 4730 -825 507 -396 C ATOM 2461 CB ASP B 466 14.126 -19.605 -11.623 1.00 35.98 C ANISOU 2461 CB ASP B 466 5985 2643 5044 -799 566 -329 C ATOM 2462 CG ASP B 466 14.980 -19.668 -10.343 1.00 37.63 C ANISOU 2462 CG ASP B 466 6297 2804 5198 -600 556 -174 C ATOM 2463 OD1 ASP B 466 15.185 -18.631 -9.683 1.00 38.27 O ANISOU 2463 OD1 ASP B 466 6230 3080 5230 -519 509 -123 O ATOM 2464 OD2 ASP B 466 15.460 -20.776 -9.985 1.00 41.34 O ANISOU 2464 OD2 ASP B 466 7013 3029 5664 -519 587 -101 O ATOM 2465 C ASP B 466 12.853 -17.487 -11.009 1.00 33.70 C ANISOU 2465 C ASP B 466 5289 2800 4716 -926 547 -316 C ATOM 2466 O ASP B 466 11.911 -18.095 -10.495 1.00 35.21 O ANISOU 2466 O ASP B 466 5552 2920 4904 -1111 636 -270 O ATOM 2467 N MSE B 467 13.146 -16.229 -10.700 1.00 32.05 N ANISOU 2467 N MSE B 467 4911 2790 4475 -810 493 -302 N ATOM 2468 CA MSE B 467 12.363 -15.426 -9.749 1.00 32.32 C ANISOU 2468 CA MSE B 467 4839 2978 4464 -867 537 -247 C ATOM 2469 CB MSE B 467 10.852 -15.367 -10.098 1.00 33.45 C ANISOU 2469 CB MSE B 467 4846 3217 4648 -1096 603 -295 C ATOM 2470 CG MSE B 467 10.480 -14.569 -11.341 1.00 34.23 C ANISOU 2470 CG MSE B 467 4734 3476 4798 -1122 530 -411 C ATOM 2471 SE MSE B 467 11.051 -12.703 -11.393 0.90 35.66 SE ANISOU 2471 SE MSE B 467 4726 3873 4950 -913 438 -429 SE ATOM 2472 CE MSE B 467 10.370 -12.081 -9.735 1.00 33.79 C ANISOU 2472 CE MSE B 467 4462 3731 4645 -908 538 -336 C ATOM 2473 C MSE B 467 12.545 -15.812 -8.285 1.00 32.77 C ANISOU 2473 C MSE B 467 5059 2956 4437 -824 593 -111 C ATOM 2474 O MSE B 467 11.814 -15.332 -7.424 1.00 33.07 O ANISOU 2474 O MSE B 467 5047 3099 4420 -886 661 -63 O ATOM 2475 N THR B 468 13.511 -16.674 -8.005 1.00 33.28 N ANISOU 2475 N THR B 468 5323 2840 4482 -705 569 -45 N ATOM 2476 CA THR B 468 13.885 -16.983 -6.629 1.00 33.89 C ANISOU 2476 CA THR B 468 5568 2851 4457 -623 589 98 C ATOM 2477 CB THR B 468 14.768 -18.251 -6.562 1.00 35.34 C ANISOU 2477 CB THR B 468 5996 2785 4646 -509 572 172 C ATOM 2478 OG1 THR B 468 13.977 -19.388 -6.930 1.00 37.79 O ANISOU 2478 OG1 THR B 468 6452 2897 5009 -697 675 166 O ATOM 2479 CG2 THR B 468 15.313 -18.475 -5.164 1.00 36.57 C ANISOU 2479 CG2 THR B 468 6321 2896 4679 -382 556 334 C ATOM 2480 C THR B 468 14.591 -15.751 -6.022 1.00 32.35 C ANISOU 2480 C THR B 468 5263 2840 4187 -460 495 111 C ATOM 2481 O THR B 468 15.453 -15.146 -6.652 1.00 30.75 O ANISOU 2481 O THR B 468 4946 2713 4024 -334 390 46 O ATOM 2482 N PRO B 469 14.192 -15.361 -4.801 1.00 32.67 N ANISOU 2482 N PRO B 469 5345 2955 4113 -481 542 189 N ATOM 2483 CA PRO B 469 14.887 -14.289 -4.133 1.00 31.19 C ANISOU 2483 CA PRO B 469 5102 2914 3836 -342 447 195 C ATOM 2484 CB PRO B 469 13.971 -13.957 -2.953 1.00 32.02 C ANISOU 2484 CB PRO B 469 5259 3094 3815 -428 558 252 C ATOM 2485 CG PRO B 469 13.209 -15.162 -2.692 1.00 35.33 C ANISOU 2485 CG PRO B 469 5828 3365 4231 -568 694 337 C ATOM 2486 CD PRO B 469 13.071 -15.891 -4.001 1.00 34.33 C ANISOU 2486 CD PRO B 469 5660 3121 4262 -648 695 268 C ATOM 2487 C PRO B 469 16.256 -14.732 -3.650 1.00 31.84 C ANISOU 2487 C PRO B 469 5312 2920 3863 -153 327 282 C ATOM 2488 O PRO B 469 16.421 -15.890 -3.258 1.00 34.25 O ANISOU 2488 O PRO B 469 5817 3054 4141 -128 356 388 O ATOM 2489 N SER B 470 17.223 -13.819 -3.690 1.00 30.20 N ANISOU 2489 N SER B 470 4990 2841 3645 -24 191 241 N ATOM 2490 CA SER B 470 18.571 -14.100 -3.234 1.00 30.87 C ANISOU 2490 CA SER B 470 5139 2908 3684 161 53 318 C ATOM 2491 CB SER B 470 19.482 -14.433 -4.402 1.00 29.68 C ANISOU 2491 CB SER B 470 4890 2716 3672 269 -11 267 C ATOM 2492 OG SER B 470 20.792 -14.608 -3.929 1.00 30.33 O ANISOU 2492 OG SER B 470 4987 2820 3717 461 -149 343 O ATOM 2493 C SER B 470 19.131 -12.899 -2.510 1.00 30.64 C ANISOU 2493 C SER B 470 5033 3057 3553 216 -65 302 C ATOM 2494 O SER B 470 18.928 -11.761 -2.930 1.00 29.05 O ANISOU 2494 O SER B 470 4674 2979 3385 159 -76 194 O ATOM 2495 N THR B 471 19.865 -13.168 -1.437 1.00 32.50 N ANISOU 2495 N THR B 471 5393 3296 3659 329 -164 411 N ATOM 2496 CA THR B 471 20.614 -12.129 -0.716 1.00 32.89 C ANISOU 2496 CA THR B 471 5386 3511 3599 384 -315 395 C ATOM 2497 CB THR B 471 20.490 -12.340 0.813 1.00 34.91 C ANISOU 2497 CB THR B 471 5860 3771 3632 403 -333 511 C ATOM 2498 OG1 THR B 471 20.876 -13.675 1.140 1.00 37.72 O ANISOU 2498 OG1 THR B 471 6384 3985 3961 514 -348 662 O ATOM 2499 CG2 THR B 471 19.028 -12.160 1.273 1.00 34.90 C ANISOU 2499 CG2 THR B 471 5958 3753 3549 246 -138 495 C ATOM 2500 C THR B 471 22.099 -12.082 -1.145 1.00 32.75 C ANISOU 2500 C THR B 471 5227 3559 3656 534 -494 396 C ATOM 2501 O THR B 471 22.890 -11.337 -0.583 1.00 34.16 O ANISOU 2501 O THR B 471 5345 3877 3756 575 -648 389 O ATOM 2502 N GLU B 472 22.465 -12.869 -2.157 1.00 31.92 N ANISOU 2502 N GLU B 472 5064 3360 3702 609 -467 396 N ATOM 2503 CA GLU B 472 23.861 -12.976 -2.589 1.00 31.44 C ANISOU 2503 CA GLU B 472 4859 3365 3724 773 -605 407 C ATOM 2504 CB GLU B 472 24.370 -14.411 -2.376 1.00 33.51 C ANISOU 2504 CB GLU B 472 5266 3476 3992 956 -618 540 C ATOM 2505 CG GLU B 472 24.422 -14.846 -0.927 1.00 37.90 C ANISOU 2505 CG GLU B 472 6031 4005 4363 1022 -691 691 C ATOM 2506 CD GLU B 472 23.763 -16.204 -0.707 1.00 44.50 C ANISOU 2506 CD GLU B 472 7139 4591 5179 1042 -560 804 C ATOM 2507 OE1 GLU B 472 24.485 -17.177 -0.350 1.00 46.85 O ANISOU 2507 OE1 GLU B 472 7556 4788 5457 1242 -630 939 O ATOM 2508 OE2 GLU B 472 22.521 -16.302 -0.892 1.00 44.38 O ANISOU 2508 OE2 GLU B 472 7216 4477 5169 856 -389 762 O ATOM 2509 C GLU B 472 24.062 -12.542 -4.036 1.00 28.34 C ANISOU 2509 C GLU B 472 4255 3014 3498 741 -565 283 C ATOM 2510 O GLU B 472 25.024 -11.859 -4.337 1.00 27.47 O ANISOU 2510 O GLU B 472 3954 3050 3434 785 -672 244 O ATOM 2511 N MSE B 473 23.145 -12.942 -4.916 1.00 26.75 N ANISOU 2511 N MSE B 473 4093 2693 3379 652 -412 224 N ATOM 2512 CA MSE B 473 23.244 -12.649 -6.358 1.00 25.55 C ANISOU 2512 CA MSE B 473 3777 2567 3364 621 -362 111 C ATOM 2513 CB MSE B 473 23.499 -13.920 -7.189 1.00 25.85 C ANISOU 2513 CB MSE B 473 3877 2448 3495 728 -290 117 C ATOM 2514 CG MSE B 473 24.655 -14.796 -6.777 1.00 28.02 C ANISOU 2514 CG MSE B 473 4194 2678 3776 959 -368 220 C ATOM 2515 SE MSE B 473 26.394 -14.027 -6.988 0.90 30.87 SE ANISOU 2515 SE MSE B 473 4253 3284 4190 1120 -526 214 SE ATOM 2516 CE MSE B 473 26.496 -13.771 -8.933 1.00 22.35 C ANISOU 2516 CE MSE B 473 2999 2234 3260 1079 -399 59 C ATOM 2517 C MSE B 473 21.954 -12.044 -6.864 1.00 23.67 C ANISOU 2517 C MSE B 473 3524 2330 3138 431 -255 20 C ATOM 2518 O MSE B 473 20.913 -12.197 -6.250 1.00 23.75 O ANISOU 2518 O MSE B 473 3657 2283 3082 333 -183 45 O ATOM 2519 N SER B 474 22.018 -11.384 -8.012 1.00 23.00 N ANISOU 2519 N SER B 474 3283 2317 3138 384 -240 -79 N ATOM 2520 CA SER B 474 20.815 -10.819 -8.621 1.00 21.94 C ANISOU 2520 CA SER B 474 3118 2194 3023 228 -154 -159 C ATOM 2521 CB SER B 474 20.425 -9.496 -7.949 1.00 20.28 C ANISOU 2521 CB SER B 474 2863 2099 2745 152 -190 -179 C ATOM 2522 OG SER B 474 19.094 -9.121 -8.284 1.00 20.72 O ANISOU 2522 OG SER B 474 2910 2154 280.

30. 97 -231 O ATOM 2523 C SER B 474 21.036 -10.602 -10.103 1.00 22.22 C ANISOU 2523 C SER B 474 3031 2262 3151 217 -130 -246 C ATOM 2524 O SER B 474 22.178 -10.392 -10.544 1.00 22.87 O ANISOU 2524 O SER B 474 3006 2412 3273 308 -185 -253 O ATOM 2525 N MSE B 475 19.942 -10.646 -10.871 1.00 22.60 N ANISOU 2525 N MSE B 475 3085 2278 3225 101 -49 -308 N ATOM 2526 CA MSE B 475 19.951 -10.117 -12.224 1.00 22.94 C ANISOU 2526 CA MSE B 475 3014 2384 331.

64. 37 -391 C ATOM 2527 CB MSE B 475 18.539 -10.126 -12.829 1.00 21.81 C ANISOU 2527 CB MSE B 475 2880 2226 3181 -76.

26. 446 C ATOM 2528 CG MSE B 475 18.108 -11.548 -13.200 1.00 24.19 C ANISOU 2528 CG MSE B 475 3308 2381 3504 -112.

93. 465 C ATOM 2529 SE MSE B 475 16.546 -11.727 -14.313 0.90 27.36 SE ANISOU 2529 SE MSE B 475 3688 2786 3921 -305 143 -557 SE ATOM 2530 CE MSE B 475 15.247 -11.070 -13.061 1.00 18.34 C ANISOU 2530 CE MSE B 475 2500 1718 2750 -406 169 -500 C ATOM 2531 C MSE B 475 20.526 -8.725 -12.161 1.00 22.17 C ANISOU 2531 C MSE B 475 2788 2424 321.

70. 108 -396 C ATOM 2532 O MSE B 475 20.131 -7.953 -11.287 1.00 21.81 O ANISOU 2532 O MSE B 475 2749 2419 311.

30. 137 -377 O ATOM 2533 N ARG B 476 21.484 -8.425 -13.055 1.00 22.25 N ANISOU 2533 N ARG B 476 2693 2497 3262 116 -127 -422 N ATOM 2534 CA ARG B 476 22.159 -7.132 -13.117 1.00 22.50 C ANISOU 2534 CA ARG B 476 2605 2648 329.

98. 188 -424 C ATOM 2535 CB ARG B 476 23.037 -7.065 -14.384 1.00 22.64 C ANISOU 2535 CB ARG B 476 2515 2725 3361 130 -162 -454 C ATOM 2536 CG ARG B 476 23.641 -5.664 -14.657 1.00 24.65 C ANISOU 2536 CG ARG B 476 2649 3092 362.

68. 205 -454 C ATOM 2537 CD ARG B 476 24.241 -5.462 -16.092 1.00 25.76 C ANISOU 2537 CD ARG B 476 2697 3299 379.

63. 145 -481 C ATOM 2538 NE ARG B 476 23.541 -6.128 -17.231 1.00 27.18 N ANISOU 2538 NE ARG B 476 2943 3428 395.

63. 58 -533 N ATOM 2539 CZ ARG B 476 22.619 -5.553 -18.020 1.00 27.94 C ANISOU 2539 CZ ARG B 476 3071 3528 4018 -39 -562 C ATOM 2540 NH1 ARG B 476 22.175 -4.295 -17.792 1.00 26.67 N ANISOU 2540 NH1 ARG B 476 2896 3395 3843 -102 -85 -540 N ATOM 2541 NH2 ARG B 476 22.108 -6.250 -19.027 1.00 19.87 N ANISOU 2541 NH2 ARG B 476 2107 2475 2969 -28.

19. 615 N ATOM 2542 C ARG B 476 21.228 -5.892 -12.998 1.00 21.11 C ANISOU 2542 C ARG B 476 2425 2504 3091 -6 -197 -447 C ATOM 2543 O ARG B 476 20.346 -5.675 -13.836 1.00 20.87 O ANISOU 2543 O ARG B 476 2391 2470 3068 -64 -149 -485 O ATOM 2544 N GLY B 477 21.432 -5.093 -11.949 1.00 21.59 N ANISOU 2544 N GLY B 477 2495 2597 3111 -19 -262 -426 N ATOM 2545 CA GLY B 477 20.682 -3.845 -11.726 1.00 20.28 C ANISOU 2545 CA GLY B 477 2344 2444 2916 -89 -267 -452 C ATOM 2546 C GLY B 477 19.265 -4.001 -11.186 1.00 19.95 C ANISOU 2546 C GLY B 477 2384 2360 2837 -110 -204 -459 C ATOM 2547 O GLY B 477 18.600 -2.995 -10.954 1.00 20.31 O ANISOU 2547 O GLY B 477 2442 2415 2859 -137 -196 -482 O ATOM 2548 N ILE B 478 18.805 -5.242 -10.986 1.00 19.45 N ANISOU 2548 N ILE B 478 2374 2245 2770 -98 -152 -437 N ATOM 2549 CA ILE B 478 17.425 -5.543 -10.523 1.00 17.96 C ANISOU 2549 CA ILE B 478 2239 2031 2556 -143 -73 -436 C ATOM 2550 CB ILE B 478 16.747 -6.700 -11.323 1.00 18.46 C ANISOU 2550 CB ILE B 478 2303 2046 2665 -189 -7 -446 C ATOM 2551 CG1 ILE B 478 17.035 -6.649 -12.849 1.00 16.97 C ANISOU 2551 CG1 ILE B 478 2037 1879 2532 -198 -24 -493 C ATOM 2552 CD1 ILE B 478 16.569 -5.382 -13.592 1.00 12.97 C ANISOU 2552 CD1 ILE B 478 1440 1453 2034 -221 -43 -526 C ATOM 2553 CG2 ILE B 478 15.216 -6.762 -11.010 1.00 18.15 C ANISOU 2553 CG2 ILE B 478 2259 2020 2616 -267.

75. 451 C ATOM 2554 C ILE B 478 17.351 -5.901 -9.018 1.00 18.54 C ANISOU 2554 C ILE B 478 2425 2075 2545 -124 -62 -387 C ATOM 2555 O ILE B 478 18.093 -6.760 -8.523 1.00 18.41 O ANISOU 2555 O ILE B 478 2476 2015 2504 -76 -93 -336 O ATOM 2556 N ARG B 479 16.435 -5.252 -8.299 1.00 18.71 N ANISOU 2556 N ARG B 479 2473 2124 2512 -148 -11 -398 N ATOM 2557 CA ARG B 479 16.205 -5.537 -6.881 1.00 19.06 C ANISOU 2557 CA ARG B 479 2640 2153 2450 -139.

24. 354 C ATOM 2558 CB ARG B 479 16.835 -4.454 -5.980 1.00 19.31 C ANISOU 2558 CB ARG B 479 2727 2220 2388 -100 -54 -375 C ATOM 2559 CG ARG B 479 18.364 -4.281 -6.108 1.00 17.90 C ANISOU 2559 CG ARG B 479 2524 2056 2221 -65 -199 -368 C ATOM 2560 CD ARG B 479 19.159 -5.504 -5.595 1.00 20.83 C ANISOU 2560 CD ARG B 479 2956 2400 2558 -12 -249 -287 C ATOM 2561 NE ARG B 479 20.603 -5.259 -5.641 1.00 22.94 N ANISOU 2561 NE ARG B 479 3160 2718 283.

31. 392 -279 N ATOM 2562 CZ ARG B 479 21.370 -5.399 -6.728 1.00 22.88 C ANISOU 2562 CZ ARG B 479 3022 2729 294.

52. 425 -288 C ATOM 2563 NH1 ARG B 479 20.850 -5.826 -7.888 1.00 18.51 N ANISOU 2563 NH1 ARG B 479 2416 2135 2482.

38. 335 -309 N ATOM 2564 NH2 ARG B 479 22.673 -5.109 -6.657 1.00 21.36 N ANISOU 2564 NH2 ARG B 479 2746 2610 275.

82. 549 -278 N ATOM 2565 C ARG B 479 14.714 -5.617 -6.625 1.00 19.99 C ANISOU 2565 C ARG B 479 2751 2287 2555 -193 157 -358 C ATOM 2566 O ARG B 479 13.908 -5.004 -7.352 1.00 19.57 O ANISOU 2566 O ARG B 479 2588 2283 2564 -214 195 -407 O ATOM 2567 N VAL B 480 14.344 -6.383 -5.600 1.00 20.85 N ANISOU 2567 N VAL B 480 2971 2367 2583 -214 231 -299 N ATOM 2568 CA VAL B 480 12.969 -6.481 -5.147 1.00 21.50 C ANISOU 2568 CA VAL B 480 3043 2486 2640 -275 379 -291 C ATOM 2569 CB VAL B 480 12.437 -7.952 -5.221 1.00 22.40 C ANISOU 2569 CB VAL B 480 3194 2531 2785 -375 465 -227 C ATOM 2570 CG1 VAL B 480 11.090 -8.086 -4.576 1.00 22.44 C ANISOU 2570 CG1 VAL B 480 3183 2592 2754 -458 630 -204 C ATOM 2571 CG2 VAL B 480 12.380 -8.430 -6.680 1.00 20.69 C ANISOU 2571 CG2 VAL B 480 2869 2287 2705 -430 428 -266 C ATOM 2572 C VAL B 480 12.858 -5.880 -3.738 1.00 23.73 C ANISOU 2572 C VAL B 480 3442 2803 2771 -231 424 -282 C ATOM 2573 O VAL B 480 13.635 -6.213 -2.833 1.00 23.83 O ANISOU 2573 O VAL B 480 3604 2779 2670 -198 372 -230 O ATOM 2574 N SER B 481 11.899 -4.968 -3.571 1.00 24.34 N ANISOU 2574 N SER B 481 3455 2956 2838 -217 517 -336 N ATOM 2575 CA SER B 481 11.641 -4.340 -2.293 1.00 26.50 C ANISOU 2575 CA SER B 481 3846 3264 2958 -169 590 -350 C ATOM 2576 CB SER B 481 10.803 -3.087 -2.498 1.00 26.56 C ANISOU 2576 CB SER B 481 3755 3338 2998 -108 659 -436 C ATOM 2577 OG SER B 481 10.413 -2.542 -1.251 1.00 29.55 O ANISOU 2577 OG SER B 481 4258 3749 3221 -56 765 -461 O ATOM 2578 C SER B 481 10.922 -5.271 -1.311 1.00 29.41 C ANISOU 2578 C SER B 481 4304 3643 3226 -230 745 -270 C ATOM 2579 O SER B 481 10.009 -6.006 -1.679 1.00 29.10 O ANISOU 2579 O SER B 481 4167 3623 3266 -319 857 -233 O ATOM 2580 N LYS B 482 11.350 -5.230 -0.054 1.00 32.28 N ANISOU 2580 N LYS B 482 4862 3998 3405 -194 747 -241 N ATOM 2581 CA LYS B 482 10.679 -5.956 1.007 1.00 36.48 C ANISOU 2581 CA LYS B 482 5512 4545 3803 -246 910 -159 C ATOM 2582 CB LYS B 482 11.708 -6.552 1.973 1.00 37.56 C ANISOU 2582 CB LYS B 482 5882 4620 3770 -223 813 -72 C ATOM 2583 CG LYS B 482 12.493 -7.739 1.427 1.00 39.17 C ANISOU 2583 CG LYS B 482 6106 4718 4059 -250 700 19 C ATOM 2584 CD LYS B 482 13.494 -8.227 2.457 1.00 46.13 C ANISOU 2584 CD LYS B 482 7211 5556 4762 -192 592 114 C ATOM 2585 CE LYS B 482 13.409 -9.749 2.690 1.00 50.34 C ANISOU 2585 CE LYS B 482 7871 5976 5278 -245 653 267 C ATOM 2586 NZ LYS B 482 14.542 -10.223 3.564 1.00 55.51 N ANISOU 2586 NZ LYS B 482 8732 6587 5770 -151 505 373 N ATOM 2587 C LYS B 482 9.701 -5.045 1.766 1.00 39.13 C ANISOU 2587 C LYS B 482 5851 4981 4035 -202 1082 -221 C ATOM 2588 O LYS B 482 9.060 -5.500 2.711 1.00 41.48 O ANISOU 2588 O LYS B 482 6242 5315 4202 -242 1250 -160 O ATOM 2589 N MSE B 483 9.603 -3.764 1.371 1.00 39.66 N ANISOU 2589 N MSE B 483 5832 5082 4154 -113 1050 -338 N ATOM 2590 CA MSE B 483 8.689 -2.788 2.016 1.00 42.78 C ANISOU 2590 CA MSE B 483 6232 5558 4464 -32 1217 -416 C ATOM 2591 CB MSE B 483 9.114 -1.322 1.779 1.00 42.34 C ANISOU 2591 CB MSE B 483 6198 5470 4417 85 1113 -544 C ATOM 2592 CG MSE B 483 10.519 -0.958 2.191 1.00 42.80 C ANISOU 2592 CG MSE B 483 6451 5447 4363 95 911 -575 C ATOM 2593 SE MSE B 483 10.790 -1.343 4.076 0.90 53.78 SE ANISOU 2593 SE MSE B 483 8155 6858 5420 89 969 -539 SE ATOM 2594 CE MSE B 483 9.681 -0.017 5.008 1.00 43.83 C ANISOU 2594 CE MSE B 483 6998 5650 4003 213 1203 -680 C ATOM 2595 C MSE B 483 7.253 -2.929 1.531 1.00 44.09 C ANISOU 2595 C MSE B 483 6165 5828 4760 -57 1407 -409 C ATOM 2596 O MSE B 483 7.028 -2.888 0.312 1.00 43.61 O ANISOU 2596 O MSE B 483 5899 5777 4893 -73 1342 -423 O ATOM 2597 OXT MSE B 483 6.311 -3.041 2.339 1.00 46.48 O ANISOU 2597 OXT MSE B 483 6471 6220 4971 -61 1623 -390 O ATOM 2598 N ILE D 319 63.442 -23.655 -17.970 1.00 53.76 N ANISOU 2598 N ILE D 319 7685 4667 8075 274 727 -949 N ATOM 2599 CA ILE D 319 62.501 -23.137 -16.919 1.00 52.62 C ANISOU 2599 CA ILE D 319 7506 4623 7863 88 628 -790 C ATOM 2600 CB ILE D 319 62.826 -23.727 -15.487 1.00 53.65 C ANISOU 2600 CB ILE D 319 7709 4559 8116 134 561 -578 C ATOM 2601 CG1 ILE D 319 61.736 -23.378 -14.463 1.00 53.18 C ANISOU 2601 CG1 ILE D 319 7660 4578 7969 -75 499 -438 C ATOM 2602 CD1 ILE D 319 61.719 -24.322 -13.234 1.00 55.09 C ANISOU 2602 CD1 ILE D 319 8066 4566 8299 -89 460 -258 C ATOM 2603 CG2 ILE D 319 64.206 -23.306 -14.994 1.00 52.60 C ANISOU 2603 CG2 ILE D 319 7451 4467 8067 373 525 -452 C ATOM 2604 C ILE D 319 62.352 -21.605 -16.916 1.00 49.28 C ANISOU 2604 C ILE D 319 6892 4530 7301 56 600 -732 C ATOM 2605 O ILE D 319 61.237 -21.097 -16.682 1.00 48.90 O ANISOU 2605 O ILE D 319 6817 4614 7147 -127 555 -712 O ATOM 2606 N SER D 320 63.458 -20.898 -17.210 1.00 47.45 N ANISOU 2606 N SER D 320 6524 4418 7087 232 634 -713 N ATOM 2607 CA SER D 320 63.576 -19.403 -17.245 1.00 43.82 C ANISOU 2607 CA SER D 320 5886 4238 6528 231 618 -650 C ATOM 2608 CB SER D 320 62.853 -18.783 -18.463 1.00 43.61 C ANISOU 2608 CB SER D 320 5846 4391 6332 139 666 -791 C ATOM 2609 OG SER D 320 62.411 -19.771 -19.397 1.00 46.63 O ANISOU 2609 OG SER D 320 6378 4652 6686 96 715 -975 O ATOM 2610 C SER D 320 63.164 -18.674 -15.938 1.00 40.81 C ANISOU 2610 C SER D 320 5444 3950 6114 147 509 -475 C ATOM 2611 O SER D 320 62.342 -17.737 -15.963 1.00 39.35 O ANISOU 2611 O SER D 320 5199 3949 5803 29 485 -470 O ATOM 2612 N SER D 321 63.744 -19.096 -14.810 1.00 38.96 N ANISOU 2612 N SER D 321 5233 3587 5982 223 441 -336 N ATOM 2613 CA SER D 321 63.435 -18.492 -13.514 1.00 35.41 C ANISOU 2613 CA SER D 321 4761 3214 5478 159 341 -177 C ATOM 2614 CB SER D 321 63.252 -19.571 -12.458 1.00 37.05 C ANISOU 2614 CB SER D 321 5133 3209 5736 139 291 -64 C ATOM 2615 OG SER D 321 64.485 -20.151 -12.113 1.00 39.50 O ANISOU 2615 OG SER D 321 5449 3370 6187 334 243 7 O ATOM 2616 C SER D 321 64.454 -17.445 -13.030 1.00 33.02 C ANISOU 2616 C SER D 321 4299 3045 5202 275 271 -86 C ATOM 2617 O SER D 321 64.263 -16.842 -11.978 1.00 31.66 O ANISOU 2617 O SER D 321 4115 2947 4966 231 181 25 O ATOM 2618 N SER D 322 65.501 -17.202 -13.829 1.00 31.16 N ANISOU 2618 N SER D 322 3939 2845 5057 410 324 -145 N ATOM 2619 CA SER D 322 66.656 -16.427 -13.420 1.00 28.20 C ANISOU 2619 CA SER D 322 3392 2555 4768 525 259 -67 C ATOM 2620 CB SER D 322 67.515 -17.350 -12.575 1.00 30.48 C ANISOU 2620 CB SER D 322 3710 2670 5202 669 164 29 C ATOM 2621 OG SER D 322 68.312 -16.682 -11.683 1.00 28.82 O ANISOU 2621 OG SER D 322 3373 2534 5042 733 26 137 O ATOM 2622 C SER D 322 67.425 -16.050 -14.688 1.00 27.21 C ANISOU 2622 C SER D 322 3127 2506 4706 610 390 -168 C ATOM 2623 O SER D 322 67.831 -16.930 -15.437 1.00 28.51 O ANISOU 2623 O SER D 322 3324 2557 4949 708 491 -255 O ATOM 2624 N PHE D 323 67.651 -14.758 -14.921 1.00 24.48 N ANISOU 2624 N PHE D 323 2638 2339 4326 576 402 -155 N ATOM 2625 CA PHE D 323 68.250 -14.299 -16.169 1.00 24.11 C ANISOU 2625 CA PHE D 323 2478 2379 4303 627 556 -233 C ATOM 2626 CB PHE D 323 67.335 -14.608 -17.378 1.00 23.01 C ANISOU 2626 CB PHE D 323 2478 2256 4010 561 682 -365 C ATOM 2627 CG PHE D 323 65.905 -14.146 -17.190 1.00 21.13 C ANISOU 2627 CG PHE D 323 2340 2096 3593 393 614 -364 C ATOM 2628 CD1 PHE D 323 65.509 -12.883 -17.609 1.00 18.06 C ANISOU 2628 CD1 PHE D 323 1896 1878 3090 321 629 -351 C ATOM 2629 CE1 PHE D 323 64.229 -12.463 -17.415 1.00 18.85 C ANISOU 2629 CE1 PHE D 323 2060 2050 3052 195 564 -350 C ATOM 2630 CZ PHE D 323 63.312 -13.289 -16.768 1.00 18.75 C ANISOU 2630 CZ PHE D 323 2157 1953 3016 115 496 -360 C ATOM 2631 CE2 PHE D 323 63.706 -14.538 -16.339 1.00 19.68 C ANISOU 2631 CE2 PHE D 323 2346 1892 3241 165 489 -361 C ATOM 2632 CD2 PHE D 323 64.977 -14.960 -16.567 1.00 18.81 C ANISOU 2632 CD2 PHE D 323 2185 1700 3264 312 540 -365 C ATOM 2633 C PHE D 323 68.551 -12.810 -16.119 1.00 23.35 C ANISOU 2633 C PHE D 323 2228 2449 4195 574 541 -174 C ATOM 2634 O PHE D 323 68.114 -12.092 -15.213 1.00 22.75 O ANISOU 2634 O PHE D 323 2155 2426 4064 488 412 -101 O ATOM 2635 N SER D 324 69.271 -12.361 -17.128 1.00 24.41 N ANISOU 2635 N SER D 324 2245 2654 4374 623 689 -212 N ATOM 2636 CA SER D 324 69.624 -10.980 -17.324 1.00 25.05 C ANISOU 2636 CA SER D 324 2189 2868 4460 566 717 -160 C ATOM 2637 CB SER D 324 71.102 -10.908 -17.645 1.00 26.25 C ANISOU 2637 CB SER D 324 2123 3028 4822 674 816 -146 C ATOM 2638 OG SER D 324 71.632 -9.664 -17.257 1.00 30.85 O ANISOU 2638 OG SER D 324 2540 3694 5489 607 763 -65 O ATOM 2639 C SER D 324 68.774 -10.395 -18.480 1.00 24.43 C ANISOU 2639 C SER D 324 2213 2890 4180 485 840 -211 C ATOM 2640 O SER D 324 68.616 -11.018 -19.533 1.00 26.03 O ANISOU 2640 O SER D 324 2506 3084 4301 525 976 -305 O ATOM 2641 N PHE D 325 68.185 -9.219 -18.275 1.00 22.46 N ANISOU 2641 N PHE D 325 1967 2727 3838 380 779 -155 N ATOM 2642 CA PHE D 325 67.496 -8.549 -19.370 1.00 21.87 C ANISOU 2642 CA PHE D 325 1975 2750 3586 326 877 -178 C ATOM 2643 CB PHE D 325 66.033 -9.046 -19.505 1.00 20.62 C ANISOU 2643 CB PHE D 325 1995 2598 3243 268 813 -247 C ATOM 2644 CG PHE D 325 65.292 -8.433 -20.664 1.00 20.13 C ANISOU 2644 CG PHE D 325 2019 2644 2985 231 879 -274 C ATOM 2645 CD1 PHE D 325 65.624 -8.761 -21.981 1.00 21.66 C ANISOU 2645 CD1 PHE D 325 2270 2870 3090 285 1038 -341 C ATOM 2646 CE1 PHE D 325 64.947 -8.172 -23.059 1.00 22.94 C ANISOU 2646 CE1 PHE D 325 2536 3141 3041 260 1079 -353 C ATOM 2647 CZ PHE D 325 63.902 -7.259 -22.812 1.00 21.18 C ANISOU 2647 CZ PHE D 325 2337 2986 2723 190 953 -296 C ATOM 2648 CE2 PHE D 325 63.581 -6.933 -21.498 1.00 16.68 C ANISOU 2648 CE2 PHE D 325 1694 2379 2264 142 816 -240 C ATOM 2649 CD2 PHE D 325 64.266 -7.516 -20.443 1.00 17.35 C ANISOU 2649 CD2 PHE D 325 1699 2364 2528 156 782 -231 C ATOM 2650 C PHE D 325 67.564 -7.047 -19.143 1.00 21.28 C ANISOU 2650 C PHE D 325 1823 2743 3519 255 845 -83 C ATOM 2651 O PHE D 325 67.193 -6.571 -18.081 1.00 20.40 O ANISOU 2651 O PHE D 325 1704 2620 3427 202 694 -41 O ATOM 2652 N GLY D 326 68.068 -6.315 -20.129 1.00 22.68 N ANISOU 2652 N GLY D 326 1956 2980 3681 255 996 -51 N ATOM 2653 CA GLY D 326 68.092 -4.857 -20.077 1.00 21.89 C ANISOU 2653 CA GLY D 326 1812 2918 3589 180 986 43 C ATOM 2654 C GLY D 326 68.926 -4.267 -18.972 1.00 21.89 C ANISOU 2654 C GLY D 326 1648 2871 3799 145 884 102 C ATOM 2655 O GLY D 326 68.699 -3.141 -18.549 1.00 22.59 O ANISOU 2655 O GLY D 326 1733 2957 3894 70 809 157 O ATOM 2656 N GLY D 327 69.900 -5.022 -18.502 1.00 23.39 N ANISOU 2656 N GLY D 327 1704 3016 4166 204 868 84 N ATOM 2657 CA GLY D 327 70.839 -4.538 -17.493 1.00 23.14 C ANISOU 2657 CA GLY D 327 1492 2951 4348 176 749 131 C ATOM 2658 C GLY D 327 70.329 -4.854 -16.096 1.00 21.75 C ANISOU 2658 C GLY D 327 1381 2731 4150 171 514 118 C ATOM 2659 O GLY D 327 70.892 -4.379 -15.118 1.00 22.68 O ANISOU 2659 O GLY D 327 1397 2828 4394 138 366 145 O ATOM 2660 N PHE D 328 69.279 -5.678 -16.009 1.00 19.65 N ANISOU 2660 N PHE D 328 1290 2454 3722 196 483 75 N ATOM 2661 CA PHE D 328 68.706 -6.111 -14.734 1.00 17.83 C ANISOU 2661 CA PHE D 328 1149 2184 3442 190 299 73 C ATOM 2662 CB PHE D 328 67.233 -5.642 -14.619 1.00 15.94 C ANISOU 2662 CB PHE D 328 1072 1982 3001 117 271 59 C ATOM 2663 CG PHE D 328 67.092 -4.187 -14.431 1.00 14.33 C ANISOU 2663 CG PHE D 328 847 1811 2787 46 236 88 C ATOM 2664 CD1 PHE D 328 67.017 -3.642 -13.141 1.00 16.78 C ANISOU 2664 CD1 PHE D 328 1171 2101 3102 9 76 98 C ATOM 2665 CE1 PHE D 328 66.918 -2.239 -12.944 1.00 15.67 C ANISOU 2665 CE1 PHE D 328 1024 1962 2966 -54 42 109 C ATOM 2666 CZ PHE D 328 66.886 -1.387 -14.054 1.00 15.40 C ANISOU 2666 CZ PHE D 328 971 1944 2938 -80 169 134 C ATOM 2667 CE2 PHE D 328 66.986 -1.913 -15.341 1.00 14.72 C ANISOU 2667 CE2 PHE D 328 873 1892 2828 -43 329 144 C ATOM 2668 CD2 PHE D 328 67.088 -3.328 -15.522 1.00 15.45 C ANISOU 2668 CD2 PHE D 328 971 1989 2910 21 362 108 C ATOM 2669 C PHE D 328 68.769 -7.623 -14.575 1.00 18.64 C ANISOU 2669 C PHE D 328 1303 2216 3563 279 290 46 C ATOM 2670 O PHE D 328 68.507 -8.386 -15.522 1.00 20.76 O ANISOU 2670 O PHE D 328 1636 2471 3780 318 422 -9 O ATOM 2671 N THR D 329 69.112 -8.074 -13.376 1.00 18.73 N ANISOU 2671 N THR D 329 1307 2172 3639 313 128 82 N ATOM 2672 CA THR D 329 69.005 -9.486 -13.040 1.00 18.53 C ANISOU 2672 CA THR D 329 1375 2049 3615 390 97 78 C ATOM 2673 CB THR D 329 70.023 -9.885 -11.931 1.00 20.11 C ANISOU 2673 CB THR D 329 1490 2190 3961 478 -77 142 C ATOM 2674 OG1 THR D 329 71.364 -9.562 -12.341 1.00 19.13 O ANISOU 2674 OG1 THR D 329 1128 2092 4050 544 -48 144 O ATOM 2675 CG2 THR D 329 69.932 -11.382 -11.615 1.00 18.59 C ANISOU 2675 CG2 THR D 329 1418 1867 3778 573 -104 159 C ATOM 2676 C THR D 329 67.566 -9.736 -12.566 1.00 17.59 C ANISOU 2676 C THR D 329 1460 1922 3302 307 61 73 C ATOM 2677 O THR D 329 67.134 -9.147 -11.597 1.00 17.15 O ANISOU 2677 O THR D 329 1450 1898 3166 247 -52 110 O ATOM 2678 N PHE D 330 66.827 -10.592 -13.275 1.00 17.78 N ANISOU 2678 N PHE D 330 1597 1907 3254 299 165 17 N ATOM 2679 CA PHE D 330 65.483 -11.015 -12.896 1.00 16.15 C ANISOU 2679 CA PHE D 330 1553 1684 2900 211 149 7 C ATOM 2680 CB PHE D 330 64.639 -11.297 -14.140 1.00 15.29 C ANISOU 2680 CB PHE D 330 1503 1600 2706 164 276 -89 C ATOM 2681 CG PHE D 330 64.137 -10.053 -14.865 1.00 14.68 C ANISOU 2681 CG PHE D 330 1379 1664 2533 108 322 -115 C ATOM 2682 CD1 PHE D 330 62.776 -9.790 -14.933 1.00 13.44 C ANISOU 2682 CD1 PHE D 330 1289 1576 2242 15 315 -144 C ATOM 2683 CE1 PHE D 330 62.297 -8.658 -15.616 1.00 12.28 C ANISOU 2683 CE1 PHE D 330 1106 1548 2011 -11 342 -157 C ATOM 2684 CZ PHE D 330 63.203 -7.777 -16.224 1.00 10.41 C ANISOU 2684 CZ PHE D 330 787 1349 1819 38 392 -129 C ATOM 2685 CE2 PHE D 330 64.553 -8.017 -16.140 1.00 10.15 C ANISOU 2685 CE2 PHE D 330 674 1255 1926 107 417 -102 C ATOM 2686 CD2 PHE D 330 65.026 -9.161 -15.481 1.00 11.56 C ANISOU 2686 CD2 PHE D 330 868 1328 2197 152 376 -101 C ATOM 2687 C PHE D 330 65.588 -12.317 -12.123 1.00 18.49 C ANISOU 2687 C PHE D 330 1952 1835 3239 255 88 51 C ATOM 2688 O PHE D 330 66.310 -13.222 -12.529 1.00 19.07 O ANISOU 2688 O PHE D 330 2014 1802 3429 356 126 32 O ATOM 2689 N LYS D 331 64.871 -12.417 -11.004 1.00 18.87 N ANISOU 2689 N LYS D 331 2112 1869 3190 188 7 114 N ATOM 2690 CA LYS D 331 64.775 -13.663 -10.273 1.00 19.84 C ANISOU 2690 CA LYS D 331 2374 1841 3323 209 -35 177 C ATOM 2691 CB LYS D 331 65.564 -13.571 -8.961 1.00 21.52 C ANISOU 2691 CB LYS D 331 2594 2030 3554 282 -199 293 C ATOM 2692 CG LYS D 331 67.070 -13.465 -9.152 1.00 23.54 C ANISOU 2692 CG LYS D 331 2684 2273 3989 429 -270 302 C ATOM 2693 CD LYS D 331 67.817 -13.640 -7.837 1.00 30.28 C ANISOU 2693 CD LYS D 331 3560 3083 4861 514 -470 419 C ATOM 2694 CE LYS D 331 69.326 -13.743 -8.063 1.00 32.87 C ANISOU 2694 CE LYS D 331 3692 3387 5410 673 -546 426 C ATOM 2695 NZ LYS D 331 70.045 -13.890 -6.766 1.00 36.55 N ANISOU 2695 NZ LYS D 331 4174 3826 5889 762 -782 540 N ATOM 2696 C LYS D 331 63.317 -13.898 -9.984 1.00 19.36 C ANISOU 2696 C LYS D 331 2445 1788 3123 64 15 174 C ATOM 2697 O LYS D 331 62.675 -13.085 -9.342 1.00 18.88 O ANISOU 2697 O LYS D 331 2391 1836 2946 -11 -10 198 O ATOM 2698 N ARG D 332 62.778 -15.009 -10.461 1.00 19.97 N ANISOU 2698 N ARG D 332 2620 1747 3223 20 93 133 N ATOM 2699 CA ARG D 332 61.355 -15.290 -10.281 1.00 19.72 C ANISOU 2699 CA ARG D 332 2679 1723 3091 -141 152 120 C ATOM 2700 CB ARG D 332 60.867 -16.358 -11.279 1.00 20.07 C ANISOU 2700 CB ARG D 332 2784 1649 3191 -199 239 17 C ATOM 2701 CG ARG D 332 59.346 -16.450 -11.354 1.00 20.01 C ANISOU 2701 CG ARG D 332 2804 1695 3106 -388 297 -30 C ATOM 2702 CD ARG D 332 58.875 -17.327 -12.504 1.00 20.70 C ANISOU 2702 CD ARG D 332 2929 1692 3243 -458 356 -169 C ATOM 2703 NE ARG D 332 59.269 -18.715 -12.316 1.00 22.45 N ANISOU 2703 NE ARG D 332 3301 1656 3571 -438 369 -145 N ATOM 2704 CZ ARG D 332 59.397 -19.590 -13.307 1.00 25.52 C ANISOU 2704 CZ ARG D 332 3753 1907 4035 -430 408 -274 C ATOM 2705 NH1 ARG D 332 59.137 -19.233 -14.566 1.00 25.47 N ANISOU 2705 NH1 ARG D 332 3678 2016 3984 -447 433 -436 N ATOM 2706 NH2 ARG D 332 59.748 -20.829 -13.035 1.00 27.36 N ANISOU 2706 NH2 ARG D 332 4137 1879 4378 -401 419 -243 N ATOM 2707 C ARG D 332 61.108 -15.726 -8.841 1.00 20.88 C ANISOU 2707 C ARG D 332 2961 1796 3175 -177 105 260 C ATOM 2708 O ARG D 332 61.801 -16.602 -8.331 1.00 21.02 O ANISOU 2708 O ARG D 332 3078 1652 3257 -95 52 348 O ATOM 2709 N THR D 333 60.149 -15.078 -8.180 1.00 20.24 N ANISOU 2709 N THR D 333 2890 1838 2964 -284 127 286 N ATOM 2710 CA THR D 333 59.820 -15.426 -6.778 1.00 21.32 C ANISOU 2710 CA THR D 333 3176 1927 2997 -328 111 423 C ATOM 2711 CB THR D 333 59.888 -14.174 -5.876 1.00 20.56 C ANISOU 2711 CB THR D 333 3051 1993 2767 -301 47 456 C ATOM 2712 OG1 THR D 333 59.095 -13.132 -6.468 1.00 19.68 O ANISOU 2712 OG1 THR D 333 2807 2049 2621 -363 113 346 O ATOM 2713 CG2 THR D 333 61.342 -13.644 -5.770 1.00 21.41 C ANISOU 2713 CG2 THR D 333 3092 2109 2933 -143 -107 471 C ATOM 2714 C THR D 333 58.450 -16.124 -6.612 1.00 22.28 C ANISOU 2714 C THR D 333 3381 2007 3077 -508 241 434 C ATOM 2715 O THR D 333 58.187 -16.719 -5.565 1.00 24.07 O ANISOU 2715 O THR D 333 3763 2148 3232 -557 263 564 O ATOM 2716 N SER D 334 57.595 -16.054 -7.636 1.00 21.08 N ANISOU 2716 N SER D 334 3124 1916 2968 -609 321 305 N ATOM 2717 CA SER D 334 56.275 -16.727 -7.644 1.00 22.78 C ANISOU 2717 CA SER D 334 3368 2099 3187 -801 437 290 C ATOM 2718 CB SER D 334 55.169 -15.774 -7.203 1.00 22.34 C ANISOU 2718 CB SER D 334 3214 2251 3025 -891 506 277 C ATOM 2719 OG SER D 334 54.919 -15.851 -5.848 1.00 26.42 O ANISOU 2719 OG SER D 334 3849 2761 3430 -928 557 413 O ATOM 2720 C SER D 334 55.889 -17.081 -9.055 1.00 21.71 C ANISOU 2720 C SER D 334 3148 1948 3153 -862 459 131 C ATOM 2721 O SER D 334 56.317 -16.426 -9.985 1.00 20.94 O ANISOU 2721 O SER D 334 2944 1944 3068 -771 412 32 O ATOM 2722 N GLY D 335 55.021 -18.077 -9.193 1.00 23.23 N ANISOU 2722 N GLY D 335 3391 2027 3407 -1030 533 108 N ATOM 2723 CA GLY D 335 54.375 -18.411 -10.458 1.00 21.87 C ANISOU 2723 CA GLY D 335 3139 1860 3310 -1132 543 -62 C ATOM 2724 C GLY D 335 55.276 -19.178 -11.397 1.00 22.97 C ANISOU 2724 C GLY D 335 3362 1826 3539 -1040 501 -149 C ATOM 2725 O GLY D 335 56.339 -19.683 -10.997 1.00 21.77 O ANISOU 2725 O GLY D 335 3331 1510 3430 -910 477 -63 O ATOM 2726 N SER D 336 54.833 -19.252 -12.651 1.00 23.39 N ANISOU 2726 N SER D 336 3346 1924 3615 -1097 487 -326 N ATOM 2727 CA SER D 336 55.445 -20.058 -13.689 1.00 25.47 C ANISOU 2727 CA SER D 336 3699 2029 3950 -1039 472 -454 C ATOM 2728 CB SER D 336 55.193 -21.560 -13.460 1.00 28.08 C ANISOU 2728 CB SER D 336 4201 2067 4403 -1165 513 -454 C ATOM 2729 OG SER D 336 53.803 -21.892 -13.365 1.00 31.54 O ANISOU 2729 OG SER D 336 4597 2519 4869 -1418 545 -493 O ATOM 2730 C SER D 336 54.844 -19.634 -15.019 1.00 25.72 C ANISOU 2730 C SER D 336 3625 2220 3926 -1088 437 -644 C ATOM 2731 O SER D 336 53.847 -18.912 -15.056 1.00 25.59 O ANISOU 2731 O SER D 336 3468 2403 3851 -1187 417 -664 O ATOM 2732 N SER D 337 55.464 -20.046 -16.117 1.00 26.46 N ANISOU 2732 N SER D 337 3787 2238 4029 -1003 427 -783 N ATOM 2733 CA SER D 337 54.928 -19.730 -17.429 1.00 27.34 C ANISOU 2733 CA SER D 337 3839 2495 4056 -1043 381 -965 C ATOM 2734 CB SER D 337 55.383 -18.344 -17.922 1.00 25.38 C ANISOU 2734 CB SER D 337 3476 2488 3680 -890 361 -946 C ATOM 2735 OG SER D 337 56.780 -18.297 -18.126 1.00 26.90 O ANISOU 2735 OG SER D 337 3722 2614 3884 -694 409 -919 O ATOM 2736 C SER D 337 55.239 -20.809 -18.446 1.00 29.10 C ANISOU 2736 C SER D 337 4212 2533 4312 -1040 389 -1148 C ATOM 2737 O SER D 337 56.117 -21.653 -18.247 1.00 29.85 O ANISOU 2737 O SER D 337 4444 2396 4503 -947 441 -1131 O ATOM 2738 N ILE D 338 54.459 -20.799 -19.515 1.00 30.44 N ANISOU 2738 N ILE D 338 4360 2804 4402 -1139 325 -1328 N ATOM 2739 CA ILE D 338 54.760 -21.558 -20.713 1.00 32.19 C ANISOU 2739 CA ILE D 338 4726 2912 4591 -1113 322 -1541 C ATOM 2740 CB ILE D 338 53.644 -22.589 -21.052 1.00 34.45 C ANISOU 2740 CB ILE D 338 5075 3071 4942 -1359 255 -1712 C ATOM 2741 CG1 ILE D 338 52.280 -21.909 -21.249 1.00 34.10 C ANISOU 2741 CG1 ILE D 338 4845 3281 4832 -1530 140 -1749 C ATOM 2742 CD1 ILE D 338 51.154 -22.880 -21.685 1.00 36.18 C ANISOU 2742 CD1 ILE D 338 5133 3442 5171 -1794.

50. 1941 C ATOM 2743 CG2 ILE D 338 53.582 -23.654 -19.966 1.00 35.56 C ANISOU 2743 CG2 ILE D 338 5308 2920 5282 -1470 315 -1615 C ATOM 2744 C ILE D 338 55.002 -20.549 -21.828 1.00 31.93 C ANISOU 2744 C ILE D 338 4641 3126 4363 -988 294 -1615 C ATOM 2745 O ILE D 338 54.712 -19.381 -21.647 1.00 30.28 O ANISOU 2745 O ILE D 338 4282 3147 4075 -964 258 -1510 O ATOM 2746 N LYS D 339 55.566 -20.983 -22.950 1.00 35.00 N ANISOU 2746 N LYS D 339 5170 3459 4671 -897 324 -1788 N ATOM 2747 CA LYS D 339 55.850 -20.096 -24.079 1.00 36.41 C ANISOU 2747 CA LYS D 339 5338 3859 4637 -776 321 -1851 C ATOM 2748 CB LYS D 339 57.326 -20.142 -24.495 1.00 36.95 C ANISOU 2748 CB LYS D 339 5494 3859 4687 -549 472 -1853 C ATOM 2749 CG LYS D 339 58.378 -19.987 -23.447 1.00 37.74 C ANISOU 2749 CG LYS D 339 5523 3868 4948 -415 568 -1657 C ATOM 2750 CD LYS D 339 59.724 -20.262 -24.109 1.00 42.28 C ANISOU 2750 CD LYS D 339 6178 4366 5520 -206 718 -1721 C ATOM 2751 CE LYS D 339 60.861 -20.353 -23.116 1.00 43.49 C ANISOU 2751 CE LYS D 339 6261 4395 5869 -62 795 -1556 C ATOM 2752 NZ LYS D 339 62.013 -21.010 -23.793 1.00 46.57 N ANISOU 2752 NZ LYS D 339 6738 4653 6302 127 942 -1667 N ATOM 2753 C LYS D 339 55.092 -20.560 -25.307 1.00 39.56 C ANISOU 2753 C LYS D 339 5843 4294 4893 -881 222 -2099 C ATOM 2754 O LYS D 339 54.885 -21.757 -25.525 1.00 41.85 O ANISOU 2754 O LYS D 339 6273 4373 5255 -979 208 -2268 O ATOM 2755 N ARG D 340 54.750 -19.599 -26.148 1.00 40.34 N ANISOU 2755 N ARG D 340 5894 4653 4779 -847 148 -2123 N ATOM 2756 CA ARG D 340 54.128 -19.873 -27.426 1.00 43.61 C ANISOU 2756 CA ARG D 340 6421 5149 5002 -912.

32. 2354 C ATOM 2757 CB ARG D 340 52.616 -19.731 -27.273 1.00 44.40 C ANISOU 2757 CB ARG D 340 6374 5372 5123 -1124 -171 -2385 C ATOM 2758 CG ARG D 340 51.801 -20.062 -28.490 1.00 48.83 C ANISOU 2758 CG ARG D 340 7023 6024 5507 -1227 -350 -2632 C ATOM 2759 CD ARG D 340 50.478 -19.350 -28.366 1.00 52.29 C ANISOU 2759 CD ARG D 340 7237 6693 5939 -1353 -548 -2586 C ATOM 2760 NE ARG D 340 49.496 -19.823 -29.329 1.00 58.76 N ANISOU 2760 NE ARG D 340 8095 7584 6649 -1504 -768 -2830 N ATOM 2761 CZ ARG D 340 48.306 -19.252 -29.509 1.00 62.04 C ANISOU 2761 CZ ARG D 340 8317 8227 7030 -1600 -982 -2837 C ATOM 2762 NH1 ARG D 340 47.964 -18.181 -28.792 1.00 60.08 N ANISOU 2762 NH1 ARG D 340 7836 8142 6848 -1546 -980 -2613 N ATOM 2763 NH2 ARG D 340 47.457 -19.748 -30.409 1.00 66.38 N ANISOU 2763 NH2 ARG D 340 8900 8838 7483 -1742 -1208 -3077 N ATOM 2764 C ARG D 340 54.699 -18.825 -28.379 1.00 43.42 C ANISOU 2764 C ARG D 340 6432 5344 4723 -731.

75. 2320 C ATOM 2765 O ARG D 340 54.666 -17.628 -28.079 1.00 41.49 O ANISOU 2765 O ARG D 340 6042 5281 4442 -669.

66. 2130 O ATOM 2766 N GLU D 341 55.293 -19.272 -29.480 1.00 45.77 N ANISOU 2766 N GLU D 341 6935 5607 4850 -638 147 -2495 N ATOM 2767 CA GLU D 341 55.826 -18.341 -30.477 1.00 46.72 C ANISOU 2767 CA GLU D 341 7119 5932 4699 -477 212 -2464 C ATOM 2768 CB GLU D 341 56.762 -19.062 -31.453 1.00 49.50 C ANISOU 2768 CB GLU D 341 7709 6182 4915 -352 375 -2651 C ATOM 2769 CG GLU D 341 57.526 -18.146 -32.413 1.00 51.74 C ANISOU 2769 CG GLU D 341 8071 6657 4932 -174 514 -2591 C ATOM 2770 CD GLU D 341 58.919 -18.672 -32.742 1.00 55.51 C ANISOU 2770 CD GLU D 341 8666 6998 5426 1 793 -2654 C ATOM 2771 OE1 GLU D 341 59.022 -19.726 -33.415 1.00 59.55 O ANISOU 2771 OE1 GLU D 341 9387 7379 5861 12 832 -2909 O ATOM 2772 OE2 GLU D 341 59.911 -18.027 -32.326 1.00 54.92 O ANISOU 2772 OE2 GLU D 341 8468 6945 5454 128 973 -2457 O ATOM 2773 C GLU D 341 54.668 -17.653 -31.202 1.00 47.34 C ANISOU 2773 C GLU D 341 7175 6260 4552 -555 -12 -2501 C ATOM 2774 O GLU D 341 53.755 -18.308 -31.666 1.00 49.11 O ANISOU 2774 O GLU D 341 7462 6479 4718 -696 -188 -2701 O ATOM 2775 N GLU D 342 54.698 -16.327 -31.260 1.00 46.37 N ANISOU 2775 N GLU D 342 6952 6343 4322 -463 -17 -2304 N ATOM 2776 CA GLU D 342 53.581 -15.557 -31.814 1.00 48.18 C ANISOU 2776 CA GLU D 342 7130 6809 4367 -510 -246 -2296 C ATOM 2777 CB GLU D 342 52.718 -14.978 -30.691 1.00 45.85 C ANISOU 2777 CB GLU D 342 6568 6567 4287 -600 -362 -2136 C ATOM 2778 CG GLU D 342 51.598 -15.878 -30.201 1.00 49.03 C ANISOU 2778 CG GLU D 342 6868 6895 4866 -815 -524 -2272 C ATOM 2779 CD GLU D 342 50.813 -15.233 -29.079 1.00 48.12 C ANISOU 2779 CD GLU D 342 6483 6849 4951 -882 -591 -2102 C ATOM 2780 OE1 GLU D 342 50.844 -15.791 -27.956 1.00 52.42 O ANISOU 2780 OE1 GLU D 342 6943 7228 5746 -975 -507 -2058 O ATOM 2781 OE2 GLU D 342 50.194 -14.158 -29.301 1.00 51.11 O ANISOU 2781 OE2 GLU D 342 6748 7440 5233 -829 -716 -2007 O ATOM 2782 C GLU D 342 54.051 -14.407 -32.683 1.00 47.55 C ANISOU 2782 C GLU D 342 7135 6921 4011 -343 -190 -2174 C ATOM 2783 O GLU D 342 55.108 -13.831 -32.436 1.00 45.79 O ANISOU 2783 O GLU D 342 6900 6671 3827 -217.

22. 2008 O ATOM 2784 N GLU D 343 53.237 -14.060 -33.674 1.00 49.19 N ANISOU 2784 N GLU D 343 7421 7319 3949 -350 -391 -2247 N ATOM 2785 CA GLU D 343 53.517 -12.924 -34.539 1.00 49.57 C ANISOU 2785 CA GLU D 343 7571 7555 3708 -200 -366 -2109 C ATOM 2786 CB GLU D 343 53.181 -13.255 -35.991 1.00 53.34 C ANISOU 2786 CB GLU D 343 8304 8158 3805 -185 -494 -2308 C ATOM 2787 CG GLU D 343 53.423 -14.707 -36.327 1.00 57.34 C ANISOU 2787 CG GLU D 343 8979 8503 4305 -258 -446 -2603 C ATOM 2788 CD GLU D 343 54.110 -14.904 -37.652 1.00 62.14 C ANISOU 2788 CD GLU D 343 9908 9165 4538 -141 -320 -2734 C ATOM 2789 OE1 GLU D 343 53.678 -14.282 -38.648 1.00 66.06 O ANISOU 2789 OE1 GLU D 343 10542 9875 4684 -85 -464 -2723 O ATOM 2790 OE2 GLU D 343 55.074 -15.699 -37.694 1.00 62.92 O ANISOU 2790 OE2 GLU D 343 10127 9092 4688 -95 -77 -2850 O ATOM 2791 C GLU D 343 52.733 -11.701 -34.073 1.00 47.50 C ANISOU 2791 C GLU D 343 7105 7439 3503 -187 -523 -1896 C ATOM 2792 O GLU D 343 51.494 -11.696 -34.101 1.00 48.59 O ANISOU 2792 O GLU D 343 7137 7683 3642 -274 -791 -1960 O ATOM 2793 N VAL D 344 53.461 -10.674 -33.637 1.00 44.51 N ANISOU 2793 N VAL D 344 6664 7057 3190 -77 -355 -1653 N ATOM 2794 CA VAL D 344 52.851 -9.406 -33.207 1.00 42.32 C ANISOU 2794 CA VAL D 344 6222 6892 2967 -33 -471 -1441 C ATOM 2795 CB VAL D 344 53.315 -8.974 -31.787 1.00 38.72 C ANISOU 2795 CB VAL D 344 5564 6310 2839 -38 -329 -1273 C ATOM 2796 CG1 VAL D 344 52.789 -9.950 -30.744 1.00 37.84 C ANISOU 2796 CG1 VAL D 344 5295 6085 2998 -187 -384 -1388 C ATOM 2797 CG2 VAL D 344 54.852 -8.867 -31.698 1.00 37.43 C ANISOU 2797 CG2 VAL D 344 5480 6029 271.

42. 33 -1181 C ATOM 2798 C VAL D 344 53.142 -8.313 -34.227 1.00 43.10 C ANISOU 2798 C VAL D 344 6482 7128 2765 114 -449 -1292 C ATOM 2799 O VAL D 344 54.177 -8.360 -34.880 1.00 43.50 O ANISOU 2799 O VAL D 344 6721 7153 2653 187 -238 -1280 O ATOM 2800 N LEU D 345 52.223 -7.349 -34.352 1.00 43.51 N ANISOU 2800 N LEU D 345 6459 7320 2751 163 -657 -1172 N ATOM 2801 CA LEU D 345 52.330 -6.227 -35.300 1.00 45.05 C ANISOU 2801 CA LEU D 345 6817 7642 2659 308 -675 -998 C ATOM 2802 CB LEU D 345 51.020 -6.033 -36.060 1.00 47.61 C ANISOU 2802 CB LEU D 345 7160 8159 2770 333 -1020 -1052 C ATOM 2803 CG LEU D 345 50.743 -6.475 -37.488 1.00 51.69 C ANISOU 2803 CG LEU D 345 7938 8822 2881 358 -1172 -1200 C ATOM 2804 CD1 LEU D 345 49.400 -5.893 -37.870 1.00 52.98 C ANISOU 2804 CD1 LEU D 345 8021 9173 2935 408 -1542 -1167 C ATOM 2805 CD2 LEU D 345 51.809 -6.018 -38.456 1.00 52.76 C ANISOU 2805 CD2 LEU D 345 8377 8975 2694 479 -945 -1081 C ATOM 2806 C LEU D 345 52.638 -4.914 -34.591 1.00 43.02 C ANISOU 2806 C LEU D 345 6443 7334 2567 390 -577 -726 C ATOM 2807 O LEU D 345 51.867 -4.483 -33.736 1.00 41.31 O ANISOU 2807 O LEU D 345 6010 7119 2567 375 -711 -671 O ATOM 2808 N THR D 346 53.739 -4.270 -34.977 1.00 43.51 N ANISOU 2808 N THR D 346 6654 7353 2525 471 -339 -564 N ATOM 2809 CA THR D 346 54.144 -3.000 -34.387 1.00 42.63 C ANISOU 2809 CA THR D 346 6463 7169 2566 535 -233 -311 C ATOM 2810 CB THR D 346 55.658 -2.699 -34.549 1.00 42.01 C ANISOU 2810 CB THR D 346 6490 6988 2482 557 105 -189 C ATOM 2811 OG1 THR D 346 55.892 -2.121 -35.833 1.00 44.89 O ANISOU 2811 OG1 THR D 346 7110 7447 2499 650 159 -72 O ATOM 2812 CG2 THR D 346 56.495 -3.942 -34.379 1.00 40.99 C ANISOU 2812 CG2 THR D 346 6357 6779 2440 484 289 -371 C ATOM 2813 C THR D 346 53.350 -1.816 -34.938 1.00 44.91 C ANISOU 2813 C THR D 346 6813 7567 2686 654 -424 -137 C ATOM 2814 O THR D 346 52.564 -1.953 -35.884 1.00 47.19 O ANISOU 2814 O THR D 346 7219 8008 2701 699 -638 -198 O ATOM 2815 N GLY D 347 53.580 -0.657 -34.312 1.00 44.77 N ANISOU 2815 N GLY D 347 6714 7455 2839 706 -353 76 N ATOM 2816 CA GLY D 347 52.914 0.595 -34.643 1.00 47.06 C ANISOU 2816 CA GLY D 347 7049 7795 3037 837 -509 273 C ATOM 2817 C GLY D 347 53.311 1.122 -35.999 1.00 50.85 C ANISOU 2817 C GLY D 347 7832 8341 3149 933 -452 421 C ATOM 2818 O GLY D 347 52.763 2.128 -36.458 1.00 53.05 O ANISOU 2818 O GLY D 347 8198 8660 3297 1060 -596 601 O ATOM 2819 N ASN D 348 54.272 0.453 -36.638 1.00 51.99 N ANISOU 2819 N ASN D 348 8144 8489 3120 885 -232 354 N ATOM 2820 CA ASN D 348 54.607 0.740 -38.029 1.00 55.74 C ANISOU 2820 CA ASN D 348 8937 9058 3184 967 -164 458 C ATOM 2821 CB ASN D 348 56.043 1.273 -38.165 1.00 56.17 C ANISOU 2821 CB ASN D 348 9099 8991 3252 953 220 639 C ATOM 2822 CG ASN D 348 56.246 2.063 -39.453 1.00 61.46 C ANISOU 2822 CG ASN D 348 10094 9733 3527 1057 289 857 C ATOM 2823 OD1 ASN D 348 55.428 2.921 -39.808 1.00 64.89 O ANISOU 2823 OD1 ASN D 348 10617 10214 3824 1167 67 1018 O ATOM 2824 ND2 ASN D 348 57.326 1.760 -40.175 1.00 64.62 N ANISOU 2824 ND2 ASN D 348 10677 10143 3734 1033 603 867 N ATOM 2825 C ASN D 348 54.350 -0.455 -38.966 1.00 57.47 C ANISOU 2825 C ASN D 348 9315 9429 3090 945 -253 215 C ATOM 2826 O ASN D 348 54.970 -0.582 -40.028 1.00 59.79 O ANISOU 2826 O ASN D 348 9882 9784 3050 980 -93 233 O ATOM 2827 N LEU D 349 53.412 -1.315 -38.557 1.00 56.20 N ANISOU 2827 N LEU D 349 8987 9325 3042 880 -504 -17 N ATOM 2828 CA LEU D 349 52.992 -2.499 -39.333 1.00 57.58 C ANISOU 2828 CA LEU D 349 9285 9625 2966 836 -647 -288 C ATOM 2829 CB LEU D 349 52.211 -2.097 -40.591 1.00 61.54 C ANISOU 2829 CB LEU D 349 10023 10324 3035 950 -912 -241 C ATOM 2830 CG LEU D 349 50.920 -1.293 -40.393 1.00 62.61 C ANISOU 2830 CG LEU D 349 10006 10547 3235 1033 -1273 -131 C ATOM 2831 CD1 LEU D 349 50.097 -1.301 -41.692 1.00 66.68 C ANISOU 2831 CD1 LEU D 349 10749 11283 3304 1126 -1593 -171 C ATOM 2832 CD2 LEU D 349 50.089 -1.802 -39.206 1.00 59.33 C ANISOU 2832 CD2 LEU D 349 9218 10095 3228 926 -1441 -291 C ATOM 2833 C LEU D 349 54.118 -3.484 -39.668 1.00 56.92 C ANISOU 2833 C LEU D 349 9346 9481 2800 775 -347 -445 C ATOM 2834 O LEU D 349 54.078 -4.191 -40.669 1.00 59.54 O ANISOU 2834 O LEU D 349 9905 9914 2802 781 -383 -615 O ATOM 2835 N GLN D 350 55.114 -3.533 -38.799 1.00 53.58 N ANISOU 2835 N GLN D 350 8781 8890 2685 724 -60 -398 N ATOM 2836 CA GLN D 350 56.191 -4.499 -38.940 1.00 52.62 C ANISOU 2836 CA GLN D 350 8734 8692 2566 681 227 -551 C ATOM 2837 CB GLN D 350 57.506 -3.890 -38.472 1.00 51.26 C ANISOU 2837 CB GLN D 350 8493 8390 2594 694 581 -356 C ATOM 2838 CG GLN D 350 58.701 -4.803 -38.614 1.00 50.19 C ANISOU 2838 CG GLN D 350 8402 8179 2489 677 898 -492 C ATOM 2839 CD GLN D 350 59.992 -4.205 -38.068 1.00 48.94 C ANISOU 2839 CD GLN D 350 8115 7899 2580 676 1225 -304 C ATOM 2840 OE1 GLN D 350 60.012 -3.105 -37.519 1.00 43.94 O ANISOU 2840 OE1 GLN D 350 7366 7218 2111 672 1213 -78 O ATOM 2841 NE2 GLN D 350 61.086 -4.936 -38.238 1.00 49.94 N ANISOU 2841 NE2 GLN D 350 8258 7972 2745 684 1516 -409 N ATOM 2842 C GLN D 350 55.865 -5.750 -38.123 1.00 50.95 C ANISOU 2842 C GLN D 350 8341 8395 2625 565 135 -811 C ATOM 2843 O GLN D 350 55.432 -5.662 -36.975 1.00 47.85 O ANISOU 2843 O GLN D 350 7690 7924 2565 50.

31. 786 O ATOM 2844 N THR D 351 56.049 -6.915 -38.728 1.00 52.61 N ANISOU 2844 N THR D 351 8702 8610 2676 537 178 -1062 N ATOM 2845 CA THR D 351 55.779 -8.175 -38.044 1.00 51.53 C ANISOU 2845 CA THR D 351 8435 8362 2782 422 105 -1310 C ATOM 2846 CB THR D 351 55.468 -9.299 -39.050 1.00 54.66 C ANISOU 2846 CB THR D 351 9064 8813 2891 39.

11. 1608 C ATOM 2847 OG1 THR D 351 54.324 -8.936 -39.833 1.00 58.05 O ANISOU 2847 OG1 THR D 351 9596 9433 3026 407 -315 -1629 O ATOM 2848 CG2 THR D 351 55.210 -10.608 -38.356 1.00 53.78 C ANISOU 2848 CG2 THR D 351 8837 8552 3047 266 -52 -1856 C ATOM 2849 C THR D 351 56.988 -8.559 -37.210 1.00 49.24 C ANISOU 2849 C THR D 351 8023 7884 2800 411 412 -1292 C ATOM 2850 O THR D 351 58.117 -8.534 -37.699 1.00 50.66 O ANISOU 2850 O THR D 351 8325 8042 2884 486 705 -1256 O ATOM 2851 N LEU D 352 56.742 -8.897 -35.949 1.00 46.43 N ANISOU 2851 N LEU D 352 7422 7404 2813 322 345 -1309 N ATOM 2852 CA LEU D 352 57.770 -9.440 -35.074 1.00 44.39 C ANISOU 2852 CA LEU D 352 7042 6963 2860 309 574 -1318 C ATOM 2853 CB LEU D 352 58.010 -8.535 -33.873 1.00 41.23 C ANISOU 2853 CB LEU D 352 6404 6502 2761 301 608 -1090 C ATOM 2854 CG LEU D 352 58.524 -7.106 -34.038 1.00 41.08 C ANISOU 2854 CG LEU D 352 6381 6541 2689 379 724 -827 C ATOM 2855 CD1 LEU D 352 58.549 -6.426 -32.663 1.00 36.89 C ANISOU 2855 CD1 LEU D 352 5605 5920 2491 342 695 -670 C ATOM 2856 CD2 LEU D 352 59.892 -7.044 -34.742 1.00 42.81 C ANISOU 2856 CD2 LEU D 352 6718 6745 2804 456 1049 -782 C ATOM 2857 C LEU D 352 57.361 -10.814 -34.566 1.00 44.29 C ANISOU 2857 C LEU D 352 6985 6825 3018 206 476 -1554 C ATOM 2858 O LEU D 352 56.238 -11.002 -34.099 1.00 43.77 O ANISOU 2858 O LEU D 352 6813 6774 3042 103 230 -1608 O ATOM 2859 N LYS D 353 58.278 -11.768 -34.669 1.00 44.79 N ANISOU 2859 N LYS D 353 7127 6756 3136 236 681 -1689 N ATOM 2860 CA LYS D 353 58.073 -13.104 -34.159 1.00 45.15 C ANISOU 2860 CA LYS D 353 7153 6632 3369 151 628 -1896 C ATOM 2861 CB LYS D 353 58.797 -14.122 -35.043 1.00 47.86 C ANISOU 2861 CB LYS D 353 7721 6897 3567 219 805 -2118 C ATOM 2862 CG LYS D 353 58.258 -15.538 -34.984 1.00 49.96 C ANISOU 2862 CG LYS D 353 8068 7007 3906 117 685 -2393 C ATOM 2863 CD LYS D 353 59.022 -16.428 -35.977 1.00 54.00 C ANISOU 2863 CD LYS D 353 8834 7446 4239 215 880 -2623 C ATOM 2864 CE LYS D 353 58.155 -17.546 -36.539 1.00 59.44 C ANISOU 2864 CE LYS D 353 9711 8070 4806 104 687 -2938 C ATOM 2865 NZ LYS D 353 58.831 -18.247 -37.687 1.00 64.80 N ANISOU 2865 NZ LYS D 353 10681 8712 5227 217 872 -3177 N ATOM 2866 C LYS D 353 58.643 -13.117 -32.754 1.00 42.12 C ANISOU 2866 C LYS D 353 6545 6092 3366 139 721 -1761 C ATOM 2867 O LYS D 353 59.852 -13.025 -32.567 1.00 41.20 O ANISOU 2867 O LYS D 353 6392 5905 3356 236 956 -1680 O ATOM 2868 N ILE D 354 57.766 -13.202 -31.758 1.00 40.54 N ANISOU 2868 N ILE D 354 6187 5851 3365 21 534 -1732 N ATOM 2869 CA ILE D 354 58.192 -13.268 -30.366 1.00 38.30 C ANISOU 2869 CA ILE D 354 5716 5424 3411 2 591 -1611 C ATOM 2870 CB ILE D 354 57.745 -12.007 -29.553 1.00 36.18 C ANISOU 2870 CB ILE D 354 5261 5254 3233 -19 498 -1388 C ATOM 2871 CG1 ILE D 354 56.211 -11.875 -29.518 1.00 36.29 C ANISOU 2871 CG1 ILE D 354 5222 5374 3193 -132 243 -1432 C ATOM 2872 CD1 ILE D 354 55.700 -10.892 -28.478 1.00 34.52 C ANISOU 2872 CD1 ILE D 354 4800 5199 3117 -155 163 -1250 C ATOM 2873 CG2 ILE D 354 58.399 -10.725 -30.109 1.00 35.98 C ANISOU 2873 CG2 ILE D 354 5252 5350 3070 93 613 -1218 C ATOM 2874 C ILE D 354 57.669 -14.549 -29.696 1.00 38.61 C ANISOU 2874 C ILE D 354 5744 5289 3636 -119 500 -1757 C ATOM 2875 O ILE D 354 56.645 -15.128 -30.109 1.00 40.64 O ANISOU 2875 O ILE D 354 6070 5566 3808 -231 333 -1922 O ATOM 2876 N ARG D 355 58.383 -15.004 -28.679 1.00 36.91 N ANISOU 2876 N ARG D 355 5447 4900 3678 -99 603 -1695 N ATOM 2877 CA ARG D 355 57.871 -16.064 -27.832 1.00 37.02 C ANISOU 2877 CA ARG D 355 5439 4735 3891 -219 522 -1768 C ATOM 2878 CB ARG D 355 58.994 -16.964 -27.340 1.00 37.88 C ANISOU 2878 CB ARG D 355 5582 4617 4194 -134 680 -1782 C ATOM 2879 CG ARG D 355 59.574 -17.833 -28.449 1.00 45.02 C ANISOU 2879 CG ARG D 355 6685 5434 4986 -48 798 -1993 C ATOM 2880 CD ARG D 355 60.668 -18.706 -27.904 1.00 52.28 C ANISOU 2880 CD ARG D 355 7615 6120 6130 61 947 -1997 C ATOM 2881 NE ARG D 355 61.771 -18.840 -28.849 1.00 59.10 N ANISOU 2881 NE ARG D 355 8572 6983 6901 238 1156 -2087 N ATOM 2882 CZ ARG D 355 62.978 -19.295 -28.524 1.00 61.64 C ANISOU 2882 CZ ARG D 355 8855 7157 7409 394 1324 -2061 C ATOM 2883 NH1 ARG D 355 63.241 -19.653 -27.265 1.00 59.91 N ANISOU 2883 NH1 ARG D 355 8522 6776 7463 396 1281 -1939 N ATOM 2884 NH2 ARG D 355 63.920 -19.396 -29.461 1.00 64.91 N ANISOU 2884 NH2 ARG D 355 9340 7592 7731 555 1536 -2157 N ATOM 2885 C ARG D 355 57.115 -15.449 -26.673 1.00 33.46 C ANISOU 2885 C ARG D 355 4803 4335 3576 -315 404 -1608 C ATOM 2886 O ARG D 355 57.717 -14.849 -25.782 1.00 30.78 O ANISOU 2886 O ARG D 355 4346 3982 3366 -256 470 -1430 O ATOM 2887 N VAL D 356 55.792 -15.577 -26.725 1.00 33.25 N ANISOU 2887 N VAL D 356 4744 4375 3512 -463 229 -1682 N ATOM 2888 CA VAL D 356 54.908 -14.994 -25.724 1.00 31.29 C ANISOU 2888 CA VAL D 356 4314 4199 3375 -555 127 -1554 C ATOM 2889 CB VAL D 356 53.495 -14.774 -26.281 1.00 32.47 C ANISOU 2889 CB VAL D 356 4410 4515 3413 -668 -69 -1643 C ATOM 2890 CG1 VAL D 356 52.532 -14.347 -25.167 1.00 31.15 C ANISOU 2890 CG1 VAL D 356 4036 4403 3395 -768 -146 -1532 C ATOM 2891 CG2 VAL D 356 53.522 -13.735 -27.416 1.00 32.66 C ANISOU 2891 CG2 VAL D 356 4479 4746 3184 -550 -115 -1624 C ATOM 2892 C VAL D 356 54.883 -15.895 -24.485 1.00 30.33 C ANISOU 2892 C VAL D 356 4157 3876 3491 -651 160 -1525 C ATOM 2893 O VAL D 356 54.610 -17.084 -24.580 1.00 31.63 O ANISOU 2893 O VAL D 356 4413 3886 3719 -754 142 -1666 O ATOM 2894 N HIS D 357 55.229 -15.330 -23.330 1.00 27.89 N ANISOU 2894 N HIS D 357 3738 3555 3304 -612 211 -1339 N ATOM 2895 CA HIS D 357 55.108 -16.067 -22.055 1.00 27.09 C ANISOU 2895 CA HIS D 357 3613 3286 3396 -703 233 -1277 C ATOM 2896 CB HIS D 357 56.157 -15.624 -21.051 1.00 24.13 C ANISOU 2896 CB HIS D 357 3198 2855 3116 -585 320 -1100 C ATOM 2897 CG HIS D 357 57.530 -16.091 -21.397 1.00 23.18 C ANISOU 2897 CG HIS D 357 3173 2605 3030 -441 426 -1120 C ATOM 2898 ND1 HIS D 357 58.182 -17.076 -20.684 1.00 23.15 N ANISOU 2898 ND1 HIS D 357 3234 2380 3180 -414 478 -1092 N ATOM 2899 CE1 HIS D 357 59.360 -17.313 -21.233 1.00 21.17 C ANISOU 2899 CE1 HIS D 357 3036 2061 2946 -261 573 -1129 C ATOM 2900 NE2 HIS D 357 59.496 -16.511 -22.275 1.00 25.10 N ANISOU 2900 NE2 HIS D 357 3515 2730 3291 -203 603 -1175 N ATOM 2901 CD2 HIS D 357 58.363 -15.742 -22.405 1.00 21.56 C ANISOU 2901 CD2 HIS D 357 3005 2457 2728 -310 501 -1165 C ATOM 2902 C HIS D 357 53.706 -15.975 -21.470 1.00 27.09 C ANISOU 2902 C HIS D 357 3488 3362 3441 -872 137 -1264 C ATOM 2903 O HIS D 357 53.151 -14.887 -21.336 1.00 26.76 O ANISOU 2903 O HIS D 357 3314 3507 3346 -858.

85. 1189 O ATOM 2904 N GLU D 358 53.130 -17.135 -21.179 1.00 28.20 N ANISOU 2904 N GLU D 358 3673 3353 3691 -1033 123 -1343 N ATOM 2905 CA GLU D 358 51.766 -17.230 -20.704 1.00 28.28 C ANISOU 2905 CA GLU D 358 3553 3425 3768 -1223.

54. 1351 C ATOM 2906 CB GLU D 358 50.984 -18.208 -21.581 1.00 31.17 C ANISOU 2906 CB GLU D 358 3968 3736 4138 -1389 -39 -1564 C ATOM 2907 CG GLU D 358 50.973 -17.773 -23.047 1.00 32.95 C ANISOU 2907 CG GLU D 358 4233 4120 4167 -1309 -143 -1709 C ATOM 2908 CD GLU D 358 50.303 -18.740 -23.964 1.00 39.33 C ANISOU 2908 CD GLU D 358 5118 4872 4954 -1465 -257 -1944 C ATOM 2909 OE1 GLU D 358 50.379 -19.974 -23.732 1.00 41.30 O ANISOU 2909 OE1 GLU D 358 5483 4874 5336 -1583 -213 -2029 O ATOM 2910 OE2 GLU D 358 49.688 -18.254 -24.939 1.00 42.18 O ANISOU 2910 OE2 GLU D 358 5432 5432 5161 -1467 -405 -2049 O ATOM 2911 C GLU D 358 51.790 -17.669 -19.252 1.00 27.36 C ANISOU 2911 C GLU D 358 3429 3163 3804 -1292 145 -1208 C ATOM 2912 O GLU D 358 52.383 -18.677 -18.925 1.00 29.08 O ANISOU 2912 O GLU D 358 3791 3148 4112 -1304 210 -1203 O ATOM 2913 N GLY D 359 51.167 -16.892 -18.380 1.00 25.52 N ANISOU 2913 N GLY D 359 3044 3064 3587 -1322 155 -1086 N ATOM 2914 CA GLY D 359 51.052 -17.255 -16.979 1.00 24.48 C ANISOU 2914 CA GLY D 359 2916 2823 3560 -1399 247 -946 C ATOM 2915 C GLY D 359 51.467 -16.139 -16.057 1.00 22.50 C ANISOU 2915 C GLY D 359 2608 2681 3262 -1265 290 -781 C ATOM 2916 O GLY D 359 52.317 -15.309 -16.401 1.00 21.03 O ANISOU 2916 O GLY D 359 2431 2564 2997 -1090 271 -754 O ATOM 2917 N TYR D 360 50.879 -16.137 -14.865 1.00 22.56 N ANISOU 2917 N TYR D 360 2564 2692 3315 -1355 359 -674 N ATOM 2918 CA TYR D 360 51.277 -15.220 -13.807 1.00 20.82 C ANISOU 2918 CA TYR D 360 2328 2542 3042 -1243 405 -527 C ATOM 2919 CB TYR D 360 50.251 -15.243 -12.659 1.00 21.78 C ANISOU 2919 CB TYR D 360 2374 2709 3191 -1377 496 -447 C ATOM 2920 CG TYR D 360 50.774 -14.552 -11.417 1.00 21.58 C ANISOU 2920 CG TYR D 360 2399 2706 3092 -1269 551 -301 C ATOM 2921 CD1 TYR D 360 50.769 -13.146 -11.321 1.00 18.96 C ANISOU 2921 CD1 TYR D 360 1967 2554 2682 -1140 525 -292 C ATOM 2922 CE1 TYR D 360 51.265 -12.515 -10.199 1.00 20.05 C ANISOU 2922 CE1 TYR D 360 2168 2704 2746 -1049 560 -185 C ATOM 2923 CZ TYR D 360 51.801 -13.280 -9.164 1.00 20.65 C ANISOU 2923 CZ TYR D 360 2411 2630 2805 -1074 608 -71 C ATOM 2924 OH TYR D 360 52.295 -12.687 -8.034 1.00 19.63 O ANISOU 2924 OH TYR D 360 2362 2519 2577 -986 619 26 O ATOM 2925 CE2 TYR D 360 51.829 -14.661 -9.238 1.00 22.70 C ANISOU 2925 CE2 TYR D 360 2775 2709 3141 -1186 635 -54 C ATOM 2926 CD2 TYR D 360 51.320 -15.292 -10.365 1.00 21.83 C ANISOU 2926 CD2 TYR D 360 2601 2570 3125 -1287 613 -175 C ATOM 2927 C TYR D 360 52.662 -15.527 -13.249 1.00 19.75 C ANISOU 2927 C TYR D 360 2358 2241 2906 -1119 426 -426 C ATOM 2928 O TYR D 360 52.983 -16.691 -12.914 1.00 20.71 O ANISOU 2928 O TYR D 360 2617 2153 3097 -1174 460 -393 O ATOM 2929 N GLU D 361 53.461 -14.477 -13.117 1.00 17.95 N ANISOU 2929 N GLU D 361 2109 2098 2614 -955 398 -371 N ATOM 2930 CA GLU D 361 54.818 -14.564 -12.568 1.00 18.25 C ANISOU 2930 CA GLU D 361 2255 2018 2660 -823 391 -276 C ATOM 2931 CB GLU D 361 55.857 -14.727 -13.665 1.00 17.09 C ANISOU 2931 CB GLU D 361 2139 1814 2541 -707 361 -349 C ATOM 2932 CG GLU D 361 55.906 -16.074 -14.343 1.00 20.73 C ANISOU 2932 CG GLU D 361 2703 2101 3074 -760 379 -440 C ATOM 2933 CD GLU D 361 56.874 -16.096 -15.496 1.00 21.89 C ANISOU 2933 CD GLU D 361 2870 2225 3221 -630 377 -530 C ATOM 2934 OE1 GLU D 361 56.789 -15.177 -16.334 1.00 21.96 O ANISOU 2934 OE1 GLU D 361 2796 2400 3148 -588 360 -586 O ATOM 2935 OE2 GLU D 361 57.713 -17.035 -15.572 1.00 26.64 O ANISOU 2935 OE2 GLU D 361 3576 2639 3905 -563 403 -540 O ATOM 2936 C GLU D 361 55.166 -13.305 -11.787 1.00 17.71 C ANISOU 2936 C GLU D 361 2137 2068 2522 -724 371 -189 C ATOM 2937 O GLU D 361 54.783 -12.180 -12.189 1.00 17.20 O ANISOU 2937 O GLU D 361 1959 2166 2408 -690 352 -229 O ATOM 2938 N GLU D 362 55.904 -13.489 -10.694 1.00 18.09 N ANISOU 2938 N GLU D 362 2281 2027 2567 -671 363 -75 N ATOM 2939 CA GLU D 362 56.464 -12.367 -9.950 1.00 19.15 C ANISOU 2939 CA GLU D 362 2393 2245 2638 -572 319 -10 C ATOM 2940 CB GLU D 362 55.949 -12.359 -8.507 1.00 19.27 C ANISOU 2940 CB GLU D 362 2482 2271 2569 -627 354 85 C ATOM 2941 CG GLU D 362 56.310 -11.107 -7.717 1.00 21.42 C ANISOU 2941 CG GLU D 362 2741 2644 2753 -541 306 118 C ATOM 2942 CD GLU D 362 55.912 -11.248 -6.250 1.00 24.81 C ANISOU 2942 CD GLU D 362 3289 3073 3065 -584 348 211 C ATOM 2943 OE1 GLU D 362 54.919 -10.639 -5.837 1.00 34.00 O ANISOU 2943 OE1 GLU D 362 4411 4356 4153 -632 428 187 O ATOM 2944 OE2 GLU D 362 56.557 -12.014 -5.516 1.00 32.91 O ANISOU 2944 OE2 GLU D 362 4457 3979 4069 -565 309 311 O ATOM 2945 C GLU D 362 57.976 -12.433 -9.968 1.00 17.74 C ANISOU 2945 C GLU D 362 2250 1975 2515 -438 247 30 C ATOM 2946 O GLU D 362 58.543 -13.501 -9.839 1.00 19.01 O ANISOU 2946 O GLU D 362 2502 1982 2740 -416 238 69 O ATOM 2947 N PHE D 363 58.617 -11.277 -10.154 1.00 17.84 N ANISOU 2947 N PHE D 363 2179 2078 2521 -348 198 20 N ATOM 2948 CA PHE D 363 60.073 -11.175 -10.225 1.00 17.84 C ANISOU 2948 CA PHE D 363 2159 2019 2600 -229 133 50 C ATOM 2949 CB PHE D 363 60.525 -10.817 -11.655 1.00 17.34 C ANISOU 2949 CB PHE D 363 1999 1994 2594 -179 169 -29 C ATOM 2950 CG PHE D 363 60.204 -11.851 -12.684 1.00 18.26 C ANISOU 2950 CG PHE D 363 2152 2047 2738 -208 236 -108 C ATOM 2951 CD1 PHE D 363 61.094 -12.897 -12.951 1.00 19.62 C ANISOU 2951 CD1 PHE D 363 2369 2076 3010 -138 249 -114 C ATOM 2952 CE1 PHE D 363 60.784 -13.856 -13.898 1.00 20.76 C ANISOU 2952 CE1 PHE D 363 2571 2145 3172 -165 312 -211 C ATOM 2953 CZ PHE D 363 59.597 -13.776 -14.610 1.00 18.79 C ANISOU 2953 CZ PHE D 363 2323 1978 2839 -274 341 -302 C ATOM 2954 CE2 PHE D 363 58.711 -12.738 -14.363 1.00 20.21 C ANISOU 2954 CE2 PHE D 363 2433 2315 2932 -338 317 -284 C ATOM 2955 CD2 PHE D 363 59.020 -11.769 -13.412 1.00 17.87 C ANISOU 2955 CD2 PHE D 363 2089 2080 2620 -298 276 -189 C ATOM 2956 C PHE D 363 60.584 -10.065 -9.329 1.00 17.94 C ANISOU 2956 C PHE D 363 2144 2096 2575 -182 50 99 C ATOM 2957 O PHE D 363 59.915 -9.014 -9.174 1.00 17.61 O ANISOU 2957 O PHE D 363 2069 2165 2459 -214 62 73 O ATOM 2958 N THR D 364 61.774 -10.269 -8.775 1.00 17.84 N ANISOU 2958 N THR D 364 2142 2012 2625 -100 -43 160 N ATOM 2959 CA THR D 364 62.589 -9.144 -8.386 1.00 18.22 C ANISOU 2959 CA THR D 364 2116 2116 2692 -50 -138 169 C ATOM 2960 CB THR D 364 63.421 -9.390 -7.113 1.00 18.94 C ANISOU 2960 CB THR D 364 2269 2152 277.

5. 284 251 C ATOM 2961 OG1 THR D 364 64.333 -10.460 -7.344 1.00 22.11 O ANISOU 2961 OG1 THR D 364 2655 2441 3304.

89. 317 293 O ATOM 2962 CG2 THR D 364 62.554 -9.703 -5.942 1.00 18.12 C ANISOU 2962 CG2 THR D 364 2332 2049 2504 -49 -289 306 C ATOM 2963 C THR D 364 63.528 -8.805 -9.555 1.00 18.43 C ANISOU 2963 C THR D 364 1999 2147 285.

8. 112 128 C ATOM 2964 O THR D 364 63.977 -9.703 -10.275 1.00 19.45 O ANISOU 2964 O THR D 364 2108 2205 307.

54. 61 116 O ATOM 2965 N MSE D 365 63.759 -7.504 -9.770 1.00 17.63 N ANISOU 2965 N MSE D 365 1808 2119 2769 0 -126 104 N ATOM 2966 CA MSE D 365 64.730 -7.023 -10.747 1.00 18.41 C ANISOU 2966 CA MSE D 365 1769 2226 299.

40. 88 87 C ATOM 2967 CB MSE D 365 64.077 -6.068 -11.759 1.00 17.25 C ANISOU 2967 CB MSE D 365 1596 2157 2801 0 10 46 C ATOM 2968 CG MSE D 365 62.868 -6.645 -12.487 1.00 16.17 C ANISOU 2968 CG MSE D 365 1532 2052 2561 -32 102 1 C ATOM 2969 SE MSE D 365 61.845 -5.313 -13.450 0.90 20.72 SE ANISOU 2969 SE MSE D 365 2093 2738 3041 -63 163 -30 SE ATOM 2970 CE MSE D 365 63.243 -4.311 -14.263 1.00 11.76 C ANISOU 2970 CE MSE D 365 852 1592 2023 -26 207 8 C ATOM 2971 C MSE D 365 65.810 -6.262 -9.991 1.00 17.87 C ANISOU 2971 C MSE D 365 1615 2153 302.

59. 218 116 C ATOM 2972 O MSE D 365 65.495 -5.340 -9.241 1.00 17.57 O ANISOU 2972 O MSE D 365 1614 2147 291.

15. 292 109 O ATOM 2973 N VAL D 366 67.068 -6.639 -10.196 1.00 18.01 N

ANISOU 2973 N VAL D 366 1510 2130 3203 125 -245 137 N

ATOM 2974 CA VAL D 366 68.202 -5.950 -9.570 1.00 18.86 C

ANISOU 2974 CA VAL D 366 1492 2239 3436 133 -384 156 C

ATOM 2975 CB VAL D 366 68.942 -6.864 -8.537 1.00 20.54 C

ANISOU 2975 CB VAL D 366 1707 2397 3701 214 -553 207 C

ATOM 2976 CG1 VAL D 366 70.186 -6.172 -7.928 1.00 20.97 C

ANISOU 2976 CG1 VAL D 366 1598 2466 3905 220 -731 215 C

ATOM 2977 CG2 VAL D 366 67.976 -7.296 -7.406 1.00 21.86 C

ANISOU 2977 CG2 VAL D 366 2095 2550 3660 195 -633 237 C

ATOM 2978 C VAL D 366 69.171 -5.358 -10.585 1.00 19.08 C

ANISOU 2978 C VAL D 366 1324 2284 3643 133 -294 147 C

ATOM 2979 O VAL D 366 69.843 -6.084 -11.309 1.00 19.34 O

ANISOU 2979 O VAL D 366 1258 2296 3796 205 -204 151 O

ATOM 2980 N GLY D 367 69.241 -4.027 -10.623 1.00 19.12 N

ANISOU 2980 N GLY D 367 1279 2316 3670 51 -305 134 N

ATOM 2981 CA GLY D 367 70.244 -3.316 -11.436 1.00 20.13 C

ANISOU 2981 CA GLY D 367 1215 2451 3984 23 -221 144 C

ATOM 2982 C GLY D 367 71.337 -2.617 -10.640 1.00 21.77 C

ANISOU 2982 C GLY D 367 1266 2642 4363 -22 -391 146 C

ATOM 2983 O GLY D 367 71.408 -2.757 -9.417 1.00 21.83 O

ANISOU 2983 O GLY D 367 1322 2639 4334 -13 -599 136 O

ATOM 2984 N LYS D 368 72.214 -1.887 -11.335 1.00 22.99 N

ANISOU 2984 N LYS D 368 1233 2797 4706 -78 -304 160 N

ATOM 2985 CA LYS D 368 73.258 -1.124 -10.655 1.00 25.77 C

ANISOU 2985 CA LYS D 368 1410 3130 5252 -153 -467 150 C

ATOM 2986 CB LYS D 368 74.267 -0.536 -11.644 1.00 27.60 C

ANISOU 2986 CB LYS D 368 1403 3363 5721 -218 -307 181 C

ATOM 2987 CG LYS D 368 75.163 -1.558 -12.320 1.00 33.38 C

ANISOU 2987 CG LYS D 368 1937 4132 6613 -110 -181 206 C

ATOM 2988 CD LYS D 368 76.116 -0.834 -13.239 1.00 40.97 C

ANISOU 2988 CD LYS D 368 2663 5104 7802 -196 4 241 C

ATOM 2989 CE LYS D 368 76.457 -1.646 -14.479 1.00 44.55 C

ANISOU 2989 CE LYS D 368 3032 5601 8293 -92 283 264 C

ATOM 2990 NZ LYS D 368 77.644 -1.037 -15.172 1.00 45.91 N

ANISOU 2990 NZ LYS D 368 2915 5795 8735 -172 454 304 N

ATOM 2991 C LYS D 368 72.654 0.026 -9.845 1.00 24.40 C

ANISOU 2991 C LYS D 368 1379 2920 4973 -257 -603 106 C

ATOM 2992 O LYS D 368 73.146 0.344 -8.779 1.00 25.32 O

ANISOU 2992 O LYS D 368 1457 3020 5142 -295 -829 68 O

ATOM 2993 N ARG D 369 71.581 0.624 -10.361 1.00 22.61 N

ANISOU 2993 N ARG D 369 1320 2680 4592 -289 -471 106 N

ATOM 2994 CA ARG D 369 71.084 1.898 -9.820 1.00 22.72 C

ANISOU 2994 CA ARG D 369 1450 2637 4547 -381 -553 61 C

ATOM 2995 CB ARG D 369 71.284 3.026 -10.839 1.00 23.23 C

ANISOU 2995 CB ARG D 369 1454 2643 4728 -474 -393 99 C

ATOM 2996 CG ARG D 369 72.739 3.461 -11.079 1.00 25.22 C

ANISOU 2996 CG ARG D 369 1448 2862 5272 -572 -395 123 C

ATOM 2997 CD ARG D 369 72.724 4.978 -11.254 1.00 27.02 C

ANISOU 2997 CD ARG D 369 1710 2974 5581 -711 -368 125 C

ATOM 2998 NE ARG D 369 73.878 5.516 -10.578 1.00 30.88 N

ANISOU 2998 NE ARG D 369 2013 3410 6311 -834 -535 79 N

ATOM 2999 CZ ARG D 369 73.901 6.588 -9.811 1.00 32.41 C

ANISOU 2999 CZ ARG D 369 2268 3495 6550 -948 -695 3 C

ATOM 3000 NH1 ARG D 369 72.814 7.329 -9.581 1.00 27.48 N

ANISOU 3000 NH1 ARG D 369 1898 2792 5751 -941 -698 -36 N

ATOM 3001 NH2 ARG D 369 75.066 6.923 -9.282 1.00 37.95 N

ANISOU 3001 NH2 ARG D 369 2761 4164 7495 -1068 -857 -43 N

ATOM 3002 C ARG D 369 69.625 1.847 -9.399 1.00 21.13 C

ANISOU 3002 C ARG D 369 1494 2450 4083 -335 -554 28 C

ATOM 3003 O ARG D 369 69.083 2.830 -8.934 1.00 21.50 O

ANISOU 3003 O ARG D 369 1657 2450 4063 -381 -605 -21 O

ATOM 3004 N ALA D 370 68.982 0.695 -9.556 1.00 20.31 N

ANISOU 3004 N ALA D 370 1467 2407 3845 -245 -491 48 N

ATOM 3005 CA ALA D 370 67.568 0.560 -9.210 1.00 19.37 C

ANISOU 3005 CA ALA D 370 1545 2315 3499 -211 -469 22 C ATOM 3006 CB ALA D 370 66.677 1.149 -10.287 1.00 17.08 C ANISOU 3006 CB ALA D 370 1309 2033 3150 -214 -301 37 C ATOM 3007 C ALA D 370 67.248 -0.884 -9.014 1.00 19.29 C ANISOU 3007 C ALA D 370 1584 2348 3395 -138 -463 43 C ATOM 3008 O ALA D 370 67.922 -1.742 -9.573 1.00 19.71 O ANISOU 3008 O ALA D 370 1534 2404 3548 -97 -417 79 O ATOM 3009 N THR D 371 66.236 -1.151 -8.200 1.00 19.16 N ANISOU 3009 N THR D 371 1728 2356 3196 -124 -499 19 N ATOM 3010 CA THR D 371 65.719 -2.493 -8.036 1.00 20.02 C ANISOU 3010 CA THR D 371 1913 2488 3207 -77 -468 48 C ATOM 3011 CB THR D 371 66.139 -3.157 -6.702 1.00 20.97 C ANISOU 3011 CB THR D 371 2102 2591 3274 -49 -635 69 C ATOM 3012 OG1 THR D 371 65.494 -2.487 -5.624 1.00 23.31 O ANISOU 3012 OG1 THR D 371 2538 2908 3410 -79 -706 26 O ATOM 3013 CG2 THR D 371 67.641 -3.122 -6.488 1.00 21.86 C ANISOU 3013 CG2 THR D 371 2068 2673 3565 -782 86 C ATOM 3014 C THR D 371 64.184 -2.423 -8.121 1.00 19.54 C ANISOU 3014 C THR D 371 1975 2472 2979 -89 -363 23 C ATOM 3015 O THR D 371 63.586 -1.359 -8.003 1.00 19.86 O ANISOU 3015 O THR D 371 2053 2526 2966 -111 -349 -18 O ATOM 3016 N ALA D 372 63.528 -3.552 -8.324 1.00 19.12 N ANISOU 3016 N ALA D 372 1973 2435 2858 -76 -288 43 N ATOM 3017 CA ALA D 372 62.076 -3.489 -8.455 1.00 17.32 C ANISOU 3017 CA ALA D 372 1816 2263 2502 -99 -191 15 C ATOM 3018 CB ALA D 372 61.686 -3.097 -9.920 1.00 17.05 C ANISOU 3018 CB ALA D 372 1709 2262 2508 -97 -82 -3 C ATOM 3019 C ALA D 372 61.442 -4.786 -8.072 1.00 16.39 C ANISOU 3019 C ALA D 372 1780 2143 2304 -114 -155 40 C ATOM 3020 O ALA D 372 62.117 -5.809 -7.986 1.00 17.78 O ANISOU 3020 O ALA D 372 1965 2259 2533 -92 -189 83 O ATOM 3021 N ILE D 373 60.138 -4.749 -7.838 1.00 16.26 N ANISOU 3021 N ILE D 373 1816 2184 2177 -149 -81 16 N ATOM 3022 CA ILE D 373 59.332 -5.958 -7.815 1.00 14.85 C ANISOU 3022 CA ILE D 373 1687 2003 1950 -195 -6 35 C ATOM 3023 CB ILE D 373 58.647 -6.199 -6.451 1.00 17.21 C ANISOU 3023 CB ILE D 373 2106 2321 2113 -231 8 63 C ATOM 3024 CG1 ILE D 373 59.646 -6.124 -5.278 1.00 14.71 C ANISOU 3024 CG1 ILE D 373 1885 1957 1748 -191 -121 110 C ATOM 3025 CD1 ILE D 373 58.992 -6.294 -3.900 1.00 16.18 C ANISOU 3025 CD1 ILE D 373 2225 2170 1751 -219 -97 142 C ATOM 3026 CG2 ILE D 373 57.892 -7.565 -6.465 1.00 14.20 C ANISOU 3026 CG2 ILE D 373 1774 1909 1713 -304 99 100 C ATOM 3027 C ILE D 373 58.275 -5.853 -8.918 1.00 15.49 C ANISOU 3027 C ILE D 373 1695 2153 2037 -225.

90. 18 C ATOM 3028 O ILE D 373 57.564 -4.846 -9.013 1.00 14.66 O ANISOU 3028 O ILE D 373 1549 2123 1896 -214 114 -57 O ATOM 3029 N LEU D 374 58.168 -6.910 -9.725 1.00 15.28 N ANISOU 3029 N LEU D 374 1656 2094 2054 -255 132 -25 N ATOM 3030 CA LEU D 374 57.294 -6.952 -10.890 1.00 14.84 C ANISOU 3030 CA LEU D 374 1534 2103 2000 -285 188 -85 C ATOM 3031 CB LEU D 374 58.116 -7.089 -12.188 1.00 13.81 C ANISOU 3031 CB LEU D 374 1370 1943 1933 -240 188 -107 C ATOM 3032 CG LEU D 374 57.391 -7.325 -13.533 1.00 16.12 C ANISOU 3032 CG LEU D 374 1628 2295 2201 -265 224 -176 C ATOM 3033 CD1 LEU D 374 56.508 -6.147 -13.943 1.00 14.16 C ANISOU 3033 CD1 LEU D 374 1315 2168 1897 -246 213 -194 C ATOM 3034 CD2 LEU D 374 58.355 -7.620 -14.697 1.00 15.29 C ANISOU 3034 CD2 LEU D 374 1528 2150 2131 -214 248 -197 C ATOM 3035 C LEU D 374 56.317 -8.127 -10.796 1.00 15.20 C ANISOU 3035 C LEU D 374 1607 2138 2030 -383 243 -101 C ATOM 3036 O LEU D 374 56.725 -9.266 -10.606 1.00 15.35 O ANISOU 3036 O LEU D 374 1699 2048 2084 -411 248 -74 O ATOM 3037 N ARG D 375 55.028 -7.827 -10.911 1.00 15.31 N ANISOU 3037 N ARG D 375 1554 2256 2009 -434 284 -144 N ATOM 3038 CA ARG D 375 54.040 -8.841 -11.218 1.00 16.30 C ANISOU 3038 CA ARG D 375 1656 2386 2152 -547 331 -184 C ATOM 3039 CB ARG D 375 52.876 -8.773 -10.272 1.00 17.01 C ANISOU 3039 CB ARG D 375 1708 2548 2207 -621 404 -172 C ATOM 3040 CG ARG D 375 53.151 -9.446 -8.924 1.00 16.88 C ANISOU 3040 CG ARG D 375 1823 2439 2152 -666 454 -83 C ATOM 3041 CD ARG D 375 52.036 -9.111 -7.966 1.00 17.47 C ANISOU 3041 CD ARG D 375 1859 2613 2166 -719 557 -71 C ATOM 3042 NE ARG D 375 52.301 -9.670 -6.649 1.00 20.64 N ANISOU 3042 NE ARG D 375 2417 2937 2488 -755 610 28 N ATOM 3043 CZ ARG D 375 51.689 -9.306 -5.525 1.00 21.86 C ANISOU 3043 CZ ARG D 375 2602 3163 2540 -771 710 60 C ATOM 3044 NH1 ARG D 375 50.773 -8.327 -5.513 1.00 20.93 N ANISOU 3044 NH1 ARG D 375 2351 3193 2408 -742 774 -10 N ATOM 3045 NH2 ARG D 375 52.012 -9.927 -4.411 1.00 23.29 N ANISOU 3045 NH2 ARG D 375 2960 3266 2625 -803 749 164 N ATOM 3046 C ARG D 375 53.565 -8.716 -12.664 1.00 17.05 C ANISOU 3046 C ARG D 375 1663 2555 2260 -548 300 -271 C ATOM 3047 O ARG D 375 53.246 -7.633 -13.155 1.00 16.83 O ANISOU 3047 O ARG D 375 1557 2634 2204 -481 270 -291 O ATOM 3048 N LYS D 376 53.476 -9.856 -13.325 1.00 18.24 N ANISOU 3048 N LYS D 376 1844 2640 2446 -624 301 -323 N ATOM 3049 CA LYS D 376 53.192 -9.905 -14.723 1.00 18.60 C ANISOU 3049 CA LYS D 376 1849 2743 2477 -625 256 -416 C ATOM 3050 CB LYS D 376 54.542 -10.061 -15.399 1.00 19.02 C ANISOU 3050 CB LYS D 376 1990 2707 2528 -534 251 -415 C ATOM 3051 CG LYS D 376 54.498 -10.388 -16.778 1.00 22.27 C ANISOU 3051 CG LYS D 376 2419 3141 2901 -532 226 -511 C ATOM 3052 CD LYS D 376 55.680 -11.228 -17.131 1.00 21.43 C ANISOU 3052 CD LYS D 376 2420 2893 2831 -488 267 -529 C ATOM 3053 CE LYS D 376 55.706 -11.320 -18.640 1.00 23.94 C ANISOU 3053 CE LYS D 376 2773 3260 3065 -460 255 -635 C ATOM 3054 NZ LYS D 376 54.576 -12.148 -19.074 1.00 23.78 N ANISOU 3054 NZ LYS D 376 2758 3250 3028 -589 205 -754 N ATOM 3055 C LYS D 376 52.271 -11.109 -14.980 1.00 20.06 C ANISOU 3055 C LYS D 376 2022 2897 2704 -780 261 -496 C ATOM 3056 O LYS D 376 52.290 -12.068 -14.216 1.00 21.47 O ANISOU 3056 O LYS D 376 2269 2952 2938 -868 315 -463 O ATOM 3057 N ALA D 377 51.449 -11.038 -16.025 1.00 20.56 N ANISOU 3057 N ALA D 377 2002 3067 2743 -817 196 -596 N ATOM 3058 CA ALA D 377 50.654 -12.164 -16.502 1.00 22.62 C ANISOU 3058 CA ALA D 377 2249 3295 3051 -974 171 -703 C ATOM 3059 CB ALA D 377 49.141 -12.016 -16.103 1.00 22.84 C ANISOU 3059 CB ALA D 377 2091 3455 3132 -1095 166 -725 C ATOM 3060 C ALA D 377 50.830 -12.200 -18.012 1.00 23.29 C ANISOU 3060 C ALA D 377 2371 3421 3056 -931.

81. 817 C ATOM 3061 O ALA D 377 51.732 -11.531 -18.538 1.00 22.97 O ANISOU 3061 O ALA D 377 2392 3399 2935 -785.

78. 786 O ATOM 3062 N THR D 378 49.995 -12.969 -18.713 1.00 24.81 N ANISOU 3062 N THR D 378 2534 3628 3263 -1062.

10. 949 N ATOM 3063 CA THR D 378 50.084 -13.071 -20.188 1.00 25.87 C ANISOU 3063 CA THR D 378 2732 3812 3286 -1028 -90 -1078 C ATOM 3064 CB THR D 378 49.044 -14.046 -20.745 1.00 27.81 C ANISOU 3064 CB THR D 378 2938 4058 3571 -1214 -185 -1242 C ATOM 3065 OG1 THR D 378 49.107 -15.264 -19.991 1.00 28.15 O ANISOU 3065 OG1 THR D 378 3047 3892 3755 -1360 -97 -1250 O ATOM 3066 CG2 THR D 378 49.290 -14.336 -22.254 1.00 28.26 C ANISOU 3066 CG2 THR D 378 3122 4136 3481 -1179 -287 -1397 C ATOM 3067 C THR D 378 49.972 -11.709 -20.898 1.00 25.13 C ANISOU 3067 C THR D 378 2574 3913 3059 -881 -169 -1044 C ATOM 3068 O THR D 378 48.904 -11.120 -20.958 1.00 26.17 O ANISOU 3068 O THR D 378 2548 4203 3193 -898 -259 -1050 O ATOM 3069 N ARG D 379 51.091 -11.219 -21.423 1.00 24.75 N ANISOU 3069 N ARG D 379 2648 3846 2911 -733 -128 -998 N ATOM 3070 CA ARG D 379 51.137 -9.937 -22.140 1.00 24.06 C ANISOU 3070 CA ARG D 379 2543 3907 2692 -591 -183 -941 C ATOM 3071 CB ARG D 379 50.530 -10.069 -23.546 1.00 25.58 C ANISOU 3071 CB ARG D 379 2771 4219 2730 -599 -324 -1065 C ATOM 3072 CG ARG D 379 51.184 -11.136 -24.401 1.00 26.56 C ANISOU 3072 CG ARG D 379 3077 4242 2772 -629 -295 -1197 C ATOM 3073 CD ARG D 379 50.803 -11.005 -25.880 1.00 28.25 C ANISOU 3073 CD ARG D 379 3373 4594 2766 -594 -431 -1303 C ATOM 3074 NE ARG D 379 51.357 -9.774 -26.432 1.00 26.17 N ANISOU 3074 NE ARG D 379 3166 4426 2352 -423 -403 -1173 N ATOM 3075 CZ ARG D 379 51.005 -9.218 -27.587 1.00 26.90 C ANISOU 3075 CZ ARG D 379 3324 4670 2228 -349 -523 -1189 C ATOM 3076 NH1 ARG D 379 50.097 -9.774 -28.377 1.00 26.03 N ANISOU 3076 NH1 ARG D 379 3225 4654 2011 -425 -705 -1348 N ATOM 3077 NH2 ARG D 379 51.574 -8.084 -27.945 1.00 25.85 N ANISOU 3077 NH2 ARG D 379 3250 4588 1983 -203 -467 -1038 N ATOM 3078 C ARG D 379 50.451 -8.817 -21.339 1.00 23.81 C ANISOU 3078 C ARG D 379 2351 3979 2718 -548 -204 -834 C ATOM 3079 O ARG D 379 49.654 -8.062 -21.877 1.00 24.12 O ANISOU 3079 O ARG D 379 2303 4167 2693 -496 -315 -835 O ATOM 3080 N ARG D 380 50.796 -8.719 -20.055 1.00 23.74 N ANISOU 3080 N ARG D 380 2316 3884 2821 -555 -101 -746 N ATOM 3081 CA ARG D 380 50.201 -7.776 -19.126 1.00 24.65 C ANISOU 3081 CA ARG D 380 2301 4071 2994 -517 -90 -664 C ATOM 3082 CB ARG D 380 48.866 -8.319 -18.591 1.00 25.94 C ANISOU 3082 CB ARG D 380 2307 4296 3251 -653 -110 -725 C ATOM 3083 CG ARG D 380 48.090 -7.378 -17.662 1.00 27.73 C ANISOU 3083 CG ARG D 380 2381 4618 3538 -606 -79 -663 C ATOM 3084 CD ARG D 380 46.845 -8.116 -17.110 1.00 32.70 C ANISOU 3084 CD ARG D 380 2844 5302 4279 -768 -57 -724 C ATOM 3085 NE ARG D 380 46.470 -7.643 -15.763 1.00 41.53 N ANISOU 3085 NE ARG D 380 3880 6440 5461 -757.

67. 655 N ATOM 3086 CZ ARG D 380 45.818 -8.377 -14.862 1.00 44.62 C ANISOU 3086 CZ ARG D 380 4194 6818 5941 -906 173 -660 C ATOM 3087 NH1 ARG D 380 45.450 -9.626 -15.147 1.00 47.78 N ANISOU 3087 NH1 ARG D 380 4579 7169 6405 -1093 162 -728 N ATOM 3088 NH2 ARG D 380 45.534 -7.858 -13.668 1.00 46.02 N ANISOU 3088 NH2 ARG D 380 4324 7025 6138 -874 301 -598 N ATOM 3089 C ARG D 380 51.163 -7.516 -17.970 1.00 22.17 C ANISOU 3089 C ARG D 380 2048 3640 2735 -477.

23. 562 C ATOM 3090 O ARG D 380 51.649 -8.448 -17.344 1.00 22.38 O ANISOU 3090 O ARG D 380 2142 3543 2819 -550.

89. 560 O ATOM 3091 N LEU D 381 51.447 -6.242 -17.712 1.00 20.15 N ANISOU 3091 N LEU D 381 1778 3415 2461 -357.

30. 478 N ATOM 3092 CA LEU D 381 52.122 -5.824 -16.482 1.00 18.33 C ANISOU 3092 CA LEU D 381 1581 3101 2282 -326 104 -398 C ATOM 3093 CB LEU D 381 52.866 -4.501 -16.698 1.00 16.65 C ANISOU 3093 CB LEU D 381 1404 2880 2041 -197.

98. 324 C ATOM 3094 CG LEU D 381 53.665 -3.909 -15.562 1.00 16.21 C ANISOU 3094 CG LEU D 381 1388 2738 2032 -163 142 -259 C ATOM 3095 CD1 LEU D 381 54.864 -3.126 -16.123 1.00 15.32 C ANISOU 3095 CD1 LEU D 381 1337 2566 1918 -87 146 -198 C ATOM 3096 CD2 LEU D 381 52.771 -3.029 -14.664 1.00 13.19 C ANISOU 3096 CD2 LEU D 381 938 2411 1663 -126 146 -254 C ATOM 3097 C LEU D 381 51.003 -5.675 -15.465 1.00 18.54 C ANISOU 3097 C LEU D 381 1498 3193 2353 -368 130 -404 C ATOM 3098 O LEU D 381 50.041 -4.942 -15.713 1.00 18.05 O ANISOU 3098 O LEU D 381 1322 3249 2289 -319.

87. 421 O ATOM 3099 N VAL D 382 51.092 -6.417 -14.358 1.00 18.79 N ANISOU 3099 N VAL D 382 1564 3152 2425 -454 205 -387 N ATOM 3100 CA VAL D 382 50.030 -6.373 -13.333 1.00 19.66 C ANISOU 3100 CA VAL D 382 1578 3326 2564 -508 270 -388 C ATOM 3101 CB VAL D 382 49.864 -7.734 -12.561 1.00 20.30 C ANISOU 3101 CB VAL D 382 1704 3327 2682 -664 351 -380 C ATOM 3102 CG1 VAL D 382 48.932 -7.592 -11.345 1.00 21.28 C ANISOU 3102 CG1 VAL D 382 1755 3516 2814 -713 462 -358 C ATOM 3103 CG2 VAL D 382 49.384 -8.852 -13.492 1.00 18.12 C ANISOU 3103 CG2 VAL D 382 1390 3040 2452 -790 311 -458 C ATOM 3104 C VAL D 382 50.355 -5.218 -12.398 1.00 20.00 C ANISOU 3104 C VAL D 382 1654 3367 2580 -399 305 -336 C ATOM 3105 O VAL D 382 49.503 -4.363 -12.132 1.00 20.34 O ANISOU 3105 O VAL D 382 1594 3506 2628 -338 324 -353 O ATOM 3106 N GLN D 383 51.602 -5.188 -11.930 1.00 20.10 N ANISOU 3106 N GLN D 383 1804 3265 2570 -368 305 -282 N ATOM 3107 CA GLN D 383 52.076 -4.128 -11.044 1.00 20.46 C ANISOU 3107 CA GLN D 383 1903 3285 2586 -280 314 -249 C ATOM 3108 CB GLN D 383 51.440 -4.281 -9.645 1.00 22.14 C ANISOU 3108 CB GLN D 383 2130 3523 2758 -323 407 -245 C ATOM 3109 CG GLN D 383 51.782 -3.166 -8.701 1.00 27.86 C ANISOU 3109 CG GLN D 383 2924 4230 3430 -231 413 -242 C ATOM 3110 CD GLN D 383 50.784 -2.962 -7.567 1.00 35.94 C ANISOU 3110 CD GLN D 383 3931 5330 4396 -236 530 -267 C ATOM 3111 OE1 GLN D 383 50.146 -3.921 -7.057 1.00 37.23 O ANISOU 3111 OE1 GLN D 383 4080 5526 4539 -341 628 -250 O ATOM 3112 NE2 GLN D 383 50.628 -1.688 -7.167 1.00 36.75 N ANISOU 3112 NE2 GLN D 383 4039 5450 4475 -122 537 -310 N ATOM 3113 C GLN D 383 53.600 -4.104 -10.977 1.00 18.47 C ANISOU 3113 C GLN D 383 1765 2914 2337 -249 266 -202 C ATOM 3114 O GLN D 383 54.256 -5.122 -11.078 1.00 18.25 O ANISOU 3114 O GLN D 383 1793 2812 2329 -299 259 -182 O ATOM 3115 N LEU D 384 54.153 -2.908 -10.828 1.00 18.23 N ANISOU 3115 N LEU D 384 1759 2860 2309 -163 230 -190 N ATOM 3116 CA LEU D 384 55.575 -2.690 -10.666 1.00 16.87 C ANISOU 3116 CA LEU D 384 1658 2587 2165 -139 179 -151 C ATOM 3117 CB LEU D 384 56.164 -2.192 -11.983 1.00 16.08 C ANISOU 3117 CB LEU D 384 1525 2473 2113 -96 154 -135 C ATOM 3118 CG LEU D 384 57.662 -1.872 -12.075 1.00 16.83 C ANISOU 3118 CG LEU D 384 1646 2475 2275 -79 119 -94 C ATOM 3119 CD1 LEU D 384 58.510 -3.146 -12.068 1.00 11.98 C ANISOU 3119 CD1 LEU D 384 1046 1808 1697 -114 119 -78 C ATOM 3120 CD2 LEU D 384 57.896 -1.065 -13.332 1.00 12.84 C ANISOU 3120 CD2 LEU D 384 1111 1973 1792 -36 133 -69 C ATOM 3121 C LEU D 384 55.832 -1.650 -9.567 1.00 17.39 C ANISOU 3121 C LEU D 384 1779 2622 2207 -96 154 -158 C ATOM 3122 O LEU D 384 55.240 -0.552 -9.591 1.00 18.03 O ANISOU 3122 O LEU D 384 1836 2732 2282 -36 164 -189 O ATOM 3123 N ILE D 385 56.704 -1.988 -8.617 1.00 16.14 N ANISOU 3123 N ILE D 385 1702 2399 2032 -119 109 -136 N ATOM 3124 CA ILE D 385 57.217 -1.037 -7.649 1.00 16.77 C ANISOU 3124 CA ILE D 385 1850 2434 2086 -88.

49. 157 C ATOM 3125 CB ILE D 385 56.942 -1.448 -6.168 1.00 17.93 C ANISOU 3125 CB ILE D 385 2109 2597 2105 -110.

57. 164 C ATOM 3126 CG1 ILE D 385 55.479 -1.806 -6.000 1.00 19.43 C ANISOU 3126 CG1 ILE D 385 2275 2882 2226 -129 188 -183 C ATOM 3127 CD1 ILE D 385 55.134 -2.472 -4.673 1.00 20.09 C ANISOU 3127 CD1 ILE D 385 2475 2988 2170 -170 242 -163 C ATOM 3128 CG2 ILE D 385 57.252 -0.256 -5.217 1.00 17.45 C ANISOU 3128 CG2 ILE D 385 2135 2503 1991 -68 -6 -224 C ATOM 3129 C ILE D 385 58.712 -0.916 -7.838 1.00 16.33 C ANISOU 3129 C ILE D 385 1790 2292 2123 -90 -48 -125 C ATOM 3130 O ILE D 385 59.401 -1.917 -7.778 1.00 15.60 O ANISOU 3130 O ILE D 385 1701 2171 2056 -114 -80 -82 O ATOM 3131 N VAL D 386 59.193 0.302 -8.082 1.00 16.79 N ANISOU 3131 N VAL D 386 1830 2302 2249 -66 -89 -145 N ATOM 3132 CA VAL D 386 60.628 0.573 -8.316 1.00 16.53 C ANISOU 3132 CA VAL D 386 1754 2189 2338 -85 -170 -117 C ATOM 3133 CB VAL D 386 60.864 1.322 -9.646 1.00 16.12 C

ANISOU 3133 CB VAL D 386 1628 2110 2389 -76 -119 -88 C

ATOM 3134 CG1 VAL D 386 62.343 1.365 -9.984 1.00 15.54 C

ANISOU 3134 CG1 VAL D 386 1475 1971 2459 -111 -161 -48 C

ATOM 3135 CG2 VAL D 386 60.077 0.665 -10.776 1.00 15.17 C

ANISOU 3135 CG2 VAL D 386 1471 2064 2228 -55 -21 -62 C

ATOM 3136 C VAL D 386 61.267 1.429 -7.207 1.00 18.00 C

ANISOU 3136 C VAL D 386 2001 2310 2527 -99 -288 -165 C

ATOM 3137 O VAL D 386 60.688 2.436 -6.757 1.00 17.63 O

ANISOU 3137 O VAL D 386 2022 2246 2432 -78 -286 -229 O

ATOM 3138 N SER D 387 62.475 1.024 -6.818 1.00 17.98 N

ANISOU 3138 N SER D 387 1968 2271 2593 -128 -398 -143 N

ATOM 3139 CA SER D 387 63.295 1.740 -5.874 1.00 19.91 C

ANISOU 3139 CA SER D 387 2246 2456 2863 -157 -549 -194 C

ATOM 3140 CB SER D 387 63.525 0.862 -4.642 1.00 20.75 C

ANISOU 3140 CB SER D 387 2441 2593 2848 -148 -662 -190 C

ATOM 3141 OG SER D 387 64.138 1.637 -3.629 1.00 26.41 O

ANISOU 3141 OG SER D 387 3222 3268 3545 -174 -828 -263 O

ATOM 3142 C SER D 387 64.614 2.081 -6.601 1.00 19.75 C

ANISOU 3142 C SER D 387 2073 2372 3058 -200 -595 -160 C

ATOM 3143 O SER D 387 65.205 1.226 -7.243 1.00 19.61 O

ANISOU 3143 O SER D 387 1949 2374 3129 -192 -563 -95 O

ATOM 3144 N GLY D 388 65.045 3.336 -6.558 1.00 20.44 N

ANISOU 3144 N GLY D 388 2147 2377 3242 -249 -648 -207 N

ATOM 3145 CA GLY D 388 66.169 3.760 -7.373 1.00 20.71 C

ANISOU 3145 CA GLY D 388 2024 2350 3495 -310 -644 -164 C

ATOM 3146 C GLY D 388 66.910 4.945 -6.819 1.00 22.28 C

ANISOU 3146 C GLY D 388 2212 2442 3810 -396 -776 -233 C

ATOM 3147 O GLY D 388 66.412 5.643 -5.960 1.00 22.74 O

ANISOU 3147 O GLY D 388 2413 2458 3769 -398 -850 -326 O

ATOM 3148 N LYS D 389 68.118 5.162 -7.318 1.00 23.01 N

ANISOU 3148 N LYS D 389 2130 2489 4124 -474 -798 -195 N

ATOM 3149 CA LYS D 389 68.973 6.226 -6.823 1.00 25.51 C

ANISOU 3149 CA LYS D 389 2401 2696 4597 -588 -939 -262 C

ATOM 3150 CB LYS D 389 70.436 5.931 -7.166 1.00 27.03 C

ANISOU 3150 CB LYS D 389 2339 2893 5036 -662 -988 -213 C

ATOM 3151 CG LYS D 389 71.016 4.768 -6.405 1.00 29.16 C

ANISOU 3151 CG LYS D 389 2536 3261 5282 -606 -1149 -218 C

ATOM 3152 CD LYS D 389 72.475 4.525 -6.778 1.00 33.37 C

ANISOU 3152 CD LYS D 389 2779 3803 6095 -662 -1193 -174 C

ATOM 3153 CE LYS D 389 73.170 3.650 -5.740 1.00 38.88 C

ANISOU 3153 CE LYS D 389 3409 4571 6792 -609 -1439 -199 C

ATOM 3154 NZ LYS D 389 74.315 2.871 -6.313 1.00 42.89 N

ANISOU 3154 NZ LYS D 389 3629 5130 7536 -578 -1414 -125 N

ATOM 3155 C LYS D 389 68.574 7.622 -7.336 1.00 25.27 C

ANISOU 3155 C LYS D 389 2446 2528 4627 -643 -846 -275 C

ATOM 3156 O LYS D 389 68.815 8.616 -6.671 1.00 27.52 O

ANISOU 3156 O LYS D 389 2792 2696 4970 -722 -969 -371 O

ATOM 3157 N ASP D 390 67.957 7.673 -8.502 1.00 23.52 N

ANISOU 3157 N ASP D 390 2238 2314 4385 -594 -643 -180 N

ATOM 3158 CA ASP D 390 67.627 8.899 -9.203 1.00 24.41 C

ANISOU 3158 CA ASP D 390 2418 2292 4565 -626 -538 -147 C

ATOM 3159 CB ASP D 390 68.851 9.494 -9.933 1.00 25.90 C

ANISOU 3159 CB ASP D 390 2446 2380 5014 -767 -487 -72 C

ATOM 3160 CG ASP D 390 69.523 8.504 -10.892 1.00 26.86 C

ANISOU 3160 CG ASP D 390 2382 2621 5204 -760 -358 41 C

ATOM 3161 OD1 ASP D 390 69.057 8.339 -12.046 1.00 26.07 O

ANISOU 3161 OD1 ASP D 390 2311 2561 5035 -701 -169 145 O

ATOM 3162 OD2 ASP D 390 70.541 7.906 -10.494 1.00 27.91 O

ANISOU 3162 OD2 ASP D 390 2341 2805 5458 -807 -451 19 O

ATOM 3163 C ASP D 390 66.538 8.541 -10.190 1.00 23.04 C

ANISOU 3163 C ASP D 390 2310 2197 4248 -508 -363 -61 C

ATOM 3164 O ASP D 390 66.326 7.369 -10.478 1.00 20.52 O

ANISOU 3164 O ASP D 390 1944 2019 3834 -443 -313 -25 O

ATOM 3165 N GLU D 391 65.854 9.559 -10.695 1.00 24.31 N

ANISOU 3165 N GLU D 391 2582 2254 4399 -480 -285 -32 N ATOM 3166 CA GLU D 391 64.698 9.375 -11.545 1.00 25.09 C ANISOU 3166 CA GLU D 391 2753 2426 4353 -357 -161 37 C ATOM 3167 CB GLU D 391 63.893 10.685 -11.645 1.00 25.59 C ANISOU 3167 CB GLU D 391 2964 2345 4414 -303 -142 33 C ATOM 3168 CG GLU D 391 63.654 11.247 -13.044 1.00 29.26 C ANISOU 3168 CG GLU D 391 3463 2757 4898 -269 -8 185 C ATOM 3169 CD GLU D 391 63.469 12.790 -13.016 1.00 31.73 C ANISOU 3169 CD GLU D 391 3910 2836 5312 -270 -16 194 C ATOM 3170 OE1 GLU D 391 63.085 13.318 -11.941 1.00 37.16 O ANISOU 3170 OE1 GLU D 391 4684 3437 5996 -243 -114 56 O ATOM 3171 OE2 GLU D 391 63.683 13.469 -14.057 1.00 34.98 O ANISOU 3171 OE2 GLU D 391 4359 3140 5793 -292 83 339 O ATOM 3172 C GLU D 391 65.058 8.781 -12.903 1.00 24.24 C ANISOU 3172 C GLU D 391 2553 2399 4260 -360 -18 171 C ATOM 3173 O GLU D 391 64.273 8.010 -13.468 1.00 22.69 O ANISOU 3173 O GLU D 391 2374 2332 3915 -266 47 200 O ATOM 3174 N GLN D 392 66.247 9.114 -13.408 1.00 24.93 N ANISOU 3174 N GLN D 392 2538 2412 4524 -473 36 242 N ATOM 3175 CA GLN D 392 66.743 8.484 -14.629 1.00 25.44 C ANISOU 3175 CA GLN D 392 2508 2561 4595 -478 192 356 C ATOM 3176 CB GLN D 392 68.044 9.130 -15.089 1.00 27.83 C ANISOU 3176 CB GLN D 392 2695 2758 5122 -620 273 435 C ATOM 3177 CG GLN D 392 68.528 8.613 -16.433 1.00 30.48 C ANISOU 3177 CG GLN D 392 2956 3178 5449 -617 479 558 C ATOM 3178 CD GLN D 392 69.873 9.190 -16.862 1.00 32.38 C ANISOU 3178 CD GLN D 392 3046 3328 5929 -770 593 641 C ATOM 3179 OE1 GLN D 392 70.866 9.160 -16.120 1.00 34.05 O ANISOU 3179 OE1 GLN D 392 3083 3509 6346 -874 503 579 O ATOM 3180 NE2 GLN D 392 69.915 9.682 -18.098 1.00 36.39 N ANISOU 3180 NE2 GLN D 392 3617 3803 6407 -787 796 790 N ATOM 3181 C GLN D 392 66.861 6.952 -14.515 1.00 23.36 C ANISOU 3181 C GLN D 392 2153 2465 4257 -425 183 315 C ATOM 3182 O GLN D 392 66.428 6.241 -15.420 1.00 22.71 O ANISOU 3182 O GLN D 392 2091 2487 4051 -353 291 361 O ATOM 3183 N SER D 393 67.396 6.449 -13.399 1.00 22.65 N ANISOU 3183 N SER D 393 1984 2391 4230 -455 43 226 N ATOM 3184 CA SER D 393 67.491 5.002 -13.124 1.00 21.47 C ANISOU 3184 CA SER D 393 1772 2367 4020 -396 13 192 C ATOM 3185 CB SER D 393 68.327 4.756 -11.883 1.00 21.62 C ANISOU 3185 CB SER D 393 1702 2368 4143 -443 -165 121 C ATOM 3186 OG SER D 393 69.540 5.423 -12.049 1.00 27.86 O ANISOU 3186 OG SER D 393 2342 3083 5162 -552 -165 148 O ATOM 3187 C SER D 393 66.148 4.332 -12.909 1.00 19.41 C ANISOU 3187 C SER D 393 1642 2192 3542 -296 -2 151 C ATOM 3188 O SER D 393 65.985 3.151 -13.253 1.00 18.62 O ANISOU 3188 O SER D 393 1522 2183 3368 -242 46 156 O ATOM 3189 N ILE D 394 65.218 5.075 -12.314 1.00 18.26 N ANISOU 3189 N ILE D 394 1621 2007 3310 -275 -63 103 N ATOM 3190 CA ILE D 394 63.857 4.613 -12.104 1.00 17.01 C ANISOU 3190 CA ILE D 394 1563 1931 2968 -189 -60 64 C ATOM 3191 CB ILE D 394 63.049 5.528 -11.111 1.00 17.01 C ANISOU 3191 CB ILE D 394 1678 1876 2909 -165 -137 -15 C ATOM 3192 CG1 ILE D 394 63.665 5.443 -9.702 1.00 17.08 C ANISOU 3192 CG1 ILE D 394 1698 1854 2938 -213 -281 -98 C ATOM 3193 CD1 ILE D 394 63.245 6.554 -8.715 1.00 19.53 C ANISOU 3193 CD1 ILE D 394 2130 2075 3217 -209 -359 -197 C ATOM 3194 CG2 ILE D 394 61.591 5.140 -11.069 1.00 15.94 C ANISOU 3194 CG2 ILE D 394 1608 1838 2612 -76 -97 -43 C ATOM 3195 C ILE D 394 63.185 4.408 -13.442 1.00 16.42 C ANISOU 3195 C ILE D 394 1505 1922 2813 -134 66 130 C ATOM 3196 O ILE D 394 62.597 3.330 -13.682 1.00 17.30 O ANISOU 3196 O ILE D 394 1618 2138 2819 -93 94 116 O ATOM 3197 N ALA D 395 63.298 5.400 -14.315 1.00 16.91 N

ANISOU 3197 N ALA D 395 1588 1917 2920 -141 135 204 N

ATOM 3198 CA ALA D 395 62.780 5.347 -15.687 1.00 17.37 C

ANISOU 3198 CA ALA D 395 1681 2033 2883 -86 242 282 C

ATOM 3199 CB ALA D 395 63.094 6.656 -16.431 1.00 18.96 C

ANISOU 3199 CB ALA D 395 1932 2120 3153 -106 307 386 C

ATOM 3200 C ALA D 395 63.322 4.179 -16.485 1.00 17.20 C

ANISOU 3200 C ALA D 395 1596 2104 2837 -93 329 304 C

ATOM 3201 O ALA D 395 62.559 3.518 -17.161 1.00 17.12 O

ANISOU 3201 O ALA D 395 1624 2193 2688 -37 361 297 O

ATOM 3202 N GLU D 396 64.642 3.945 -16.431 1.00 18.24 N

ANISOU 3202 N GLU D 396 1621 2199 3109 -159 365 321 N

ATOM 3203 CA GLU D 396 65.268 2.754 -17.052 1.00 19.05 C

ANISOU 3203 CA GLU D 396 1650 2376 3211 -147 455 320 C

ATOM 3204 CB GLU D 396 66.786 2.709 -16.793 1.00 19.83 C

ANISOU 3204 CB GLU D 396 1592 2423 3518 -212 479 336 C

ATOM 3205 CG GLU D 396 67.552 3.855 -17.468 1.00 25.11 C

ANISOU 3205 CG GLU D 396 2219 3017 4306 -286 591 433 C

ATOM 3206 CD GLU D 396 69.015 4.000 -17.021 1.00 27.94 C

ANISOU 3206 CD GLU D 396 2381 3319 4915 -376 586 439 C

ATOM 3207 OE1 GLU D 396 69.468 3.298 -16.076 1.00 34.31 O

ANISOU 3207 OE1 GLU D 396 3089 4143 5805 -369 459 366 O

ATOM 3208 OE2 GLU D 396 69.726 4.828 -17.643 1.00 32.70 O

ANISOU 3208 OE2 GLU D 396 2925 3862 5638 -458 709 525 O

ATOM 3209 C GLU D 396 64.601 1.433 -16.628 1.00 16.89 C

ANISOU 3209 C GLU D 396 1399 2181 2836 -97 395 236 C

ATOM 3210 O GLU D 396 64.337 0.594 -17.467 1.00 17.29 O

ANISOU 3210 O GLU D 396 1477 2301 2790 -57 470 225 O

ATOM 3211 N ALA D 397 64.318 1.260 -15.340 1.00 16.42 N

ANISOU 3211 N ALA D 397 1346 2104 2788 -105 265 178 N

ATOM 3212 CA ALA D 397 63.635 0.071 -14.829 1.00 15.26 C

ANISOU 3212 CA ALA D 397 1236 2012 2549 -75 218 117 C

ATOM 3213 CB ALA D 397 63.668 0.033 -13.291 1.00 15.13 C

ANISOU 3213 CB ALA D 397 1230 1961 2557 -95 85 78 C

ATOM 3214 C ALA D 397 62.215 -0.057 -15.320 1.00 15.97 C

ANISOU 3214 C ALA D 397 1408 2176 2484 -43 238 95 C

ATOM 3215 O ALA D 397 61.786 -1.172 -15.654 1.00 16.45 O

ANISOU 3215 O ALA D 397 1487 2289 2476 -32 262 58 O

ATOM 3216 N ILE D 398 61.462 1.059 -15.321 1.00 16.01 N

ANISOU 3216 N ILE D 398 1457 2178 2446 -26 217 108 N

ATOM 3217 CA ILE D 398 60.095 1.065 -15.859 1.00 16.25 C

ANISOU 3217 CA ILE D 398 1533 2291 2348 19 219 92 C

ATOM 3218 CB ILE D 398 59.352 2.440 -15.637 1.00 16.90 C

ANISOU 3218 CB ILE D 398 1654 2346 2422 64 182 109 C

ATOM 3219 CG1 ILE D 398 59.198 2.757 -14.154 1.00 16.25 C

ANISOU 3219 CG1 ILE D 398 1581 2218 2376 53 117 51 C

ATOM 3220 CD1 ILE D 398 58.939 4.211 -13.831 1.00 17.39 C

ANISOU 3220 CD1 ILE D 398 1771 2278 2557 94 91 55 C

ATOM 3221 CG2 ILE D 398 57.975 2.398 -16.248 1.00 15.79 C

ANISOU 3221 CG2 ILE D 398 1524 2306 2169 127 170 95 C

ATOM 3222 C ILE D 398 60.089 0.658 -17.357 1.00 16.35 C

ANISOU 3222 C ILE D 398 1563 2365 2282 40 294 120 C

ATOM 3223 O ILE D 398 59.343 -0.227 -17.770 1.00 16.18 O

ANISOU 3223 O ILE D 398 1555 2424 2169 47 288 69 O

ATOM 3224 N ILE D 399 60.961 1.269 -18.152 1.00 16.83 N

ANISOU 3224 N ILE D 399 1632 2386 2379 41 371 196 N

ATOM 3225 CA ILE D 399 61.094 0.870 -19.567 1.00 16.97 C

ANISOU 3225 CA ILE D 399 1691 2465 2293 64 463 222 C

ATOM 3226 CB ILE D 399 62.227 1.668 -20.302 1.00 18.12 C

ANISOU 3226 CB ILE D 399 1838 2552 2495 49 584 328 C

ATOM 3227 CG1 ILE D 399 61.855 3.147 -20.442 1.00 16.73 C

ANISOU 3227 CG1 ILE D 399 1724 2317 2315 67 562 423 C

ATOM 3228 CD1 ILE D 399 63.062 4.110 -20.649 1.00 18.57 C

ANISOU 3228 CD1 ILE D 399 1936 2437 2683 8 667 531 C

ATOM 3229 CG2 ILE D 399 62.537 1.045 -21.698 1.00 17.41 C

ANISOU 3229 CG2 ILE D 399 1800 2535 2278 75 713 340 C ATOM 3230 C ILE D 399 61.312 -0.653 -19.738 1.00 16.98 C ANISOU 3230 C ILE D 399 1675 2507 2269 53 495 138 C ATOM 3231 O ILE D 399 60.592 -1.306 -20.497 1.00 17.78 O ANISOU 3231 O ILE D 399 1832 2687 2237 73 491 87 O ATOM 3232 N VAL D 400 62.307 -1.207 -19.045 1.00 16.61 N ANISOU 3232 N VAL D 400 1556 2398 2359 26 512 120 N ATOM 3233 CA VAL D 400 62.608 -2.659 -19.102 1.00 15.36 C ANISOU 3233 CA VAL D 400 1388 2241 2209 32 541 46 C ATOM 3234 CB VAL D 400 63.878 -2.999 -18.262 1.00 16.29 C ANISOU 3234 CB VAL D 400 1403 2277 2508 26 542 57 C ATOM 3235 CG1 VAL D 400 64.115 -4.500 -18.195 1.00 13.50 C ANISOU 3235 CG1 VAL D 400 1055 1897 2178 53 557 -12 C ATOM 3236 CG2 VAL D 400 65.116 -2.244 -18.837 1.00 13.64 C ANISOU 3236 CG2 VAL D 400 986 1920 2278 24 654 130 C ATOM 3237 C VAL D 400 61.412 -3.538 -18.702 1.00 15.40 C ANISOU 3237 C VAL D 400 1440 2279 2133 16 456 -35 C ATOM 3238 O VAL D 400 61.069 -4.500 -19.408 1.00 16.47 O ANISOU 3238 O VAL D 400 1626 2443 2188 19 485 -105 O ATOM 3239 N ALA D 401 60.759 -3.208 -17.597 1.00 14.49 N ANISOU 3239 N ALA D 401 1311 2156 2037 -10 363 -33 N ATOM 3240 CA ALA D 401 59.557 -3.930 -17.183 1.00 14.67 C ANISOU 3240 CA ALA D 401 1359 2218 1996 -43 305 -97 C ATOM 3241 CB ALA D 401 59.103 -3.452 -15.809 1.00 13.69 C ANISOU 3241 CB ALA D 401 1219 2081 1904 -63 238 -82 C ATOM 3242 C ALA D 401 58.398 -3.848 -18.208 1.00 15.39 C ANISOU 3242 C ALA D 401 1478 2411 1958 -37 291 -135 C ATOM 3243 O ALA D 401 57.713 -4.818 -18.452 1.00 16.06 O ANISOU 3243 O ALA D 401 1579 2526 1997 -76 274 -209 O ATOM 3244 N MSE D 402 58.174 -2.688 -18.801 1.00 16.28 N ANISOU 3244 N MSE D 402 1597 2569 2018 10 285 -82 N ATOM 3245 CA MSE D 402 57.144 -2.553 -19.841 1.00 18.26 C ANISOU 3245 CA MSE D 402 1875 2926 2137 36 243 -106 C ATOM 3246 CB MSE D 402 56.928 -1.071 -20.204 1.00 18.49 C ANISOU 3246 CB MSE D 402 1919 2974 2132 108 222 -14 C ATOM 3247 CG MSE D 402 56.199 -0.248 -19.135 1.00 17.60 C ANISOU 3247 CG MSE D 402 1749 2850 2087 130 160 -1 C ATOM 3248 SE MSE D 402 56.146 1.624 -19.687 0.90 22.98 SE ANISOU 3248 SE MSE D 402 2485 3496 2753 237 146 125 SE ATOM 3249 CE MSE D 402 55.076 2.410 -18.255 1.00 21.33 C ANISOU 3249 CE MSE D 402 2203 3271 2632 282 78 86 C ATOM 3250 C MSE D 402 57.429 -3.401 -21.105 1.00 17.59 C ANISOU 3250 C MSE D 402 1861 2875 1947 35 288 -158 C ATOM 3251 O MSE D 402 56.527 -4.090 -21.622 1.00 17.86 O ANISOU 3251 O MSE D 402 1912 2982 1891 9 226 -245 O ATOM 3252 N VAL D 403 58.675 -3.365 -21.578 1.00 17.04 N ANISOU 3252 N VAL D 403 1828 2753 1894 59 399 -117 N ATOM 3253 CA VAL D 403 59.106 -4.194 -22.698 1.00 17.23 C ANISOU 3253 CA VAL D 403 1930 2797 1818 71 477 -179 C ATOM 3254 CB VAL D 403 60.556 -3.848 -23.174 1.00 18.02 C ANISOU 3254 CB VAL D 403 2039 2850 1958 109 637 -106 C ATOM 3255 CG1 VAL D 403 61.044 -4.814 -24.226 1.00 17.77 C ANISOU 3255 CG1 VAL D 403 2091 2834 1828 135 747 -191 C ATOM 3256 CG2 VAL D 403 60.625 -2.412 -23.711 1.00 17.84 C ANISOU 3256 CG2 VAL D 403 2047 2857 1873 143 665 26 C ATOM 3257 C VAL D 403 58.943 -5.683 -22.346 1.00 17.40 C ANISOU 3257 C VAL D 403 1955 2774 1884 20 460 -304 C ATOM 3258 O VAL D 403 58.320 -6.447 -23.087 1.00 17.38 O ANISOU 3258 O VAL D 403 2019 2816 1768 -1 427 -409 O ATOM 3259 N PHE D 404 59.463 -6.068 -21.187 1.00 16.85 N ANISOU 3259 N PHE D 404 1821 2605 1975 -4 468 -290 N ATOM 3260 CA PHE D 404 59.430 -7.453 -20.709 1.00 16.94 C ANISOU 3260 CA PHE D 404 1850 2535 2053 -47 459 -377 C ATOM 3261 CB PHE D 404 60.112 -7.514 -19.346 1.00 15.89 C ANISOU 3261 CB PHE D 404 1652 2303 2081 -48 451 -311 C ATOM 3262 CG PHE D 404 60.205 -8.886 -18.770 1.00 14.98 C ANISOU 3262 CG PHE D 404 1571 2077 2043 -77 445 -364 C ATOM 3263 CD1 PHE D 404 61.249 -9.757 -19.143 1.00 15.77 C ANISOU 3263 CD1 PHE D 404 1698 2082 2212 -16 525 -400 C ATOM 3264 CE1 PHE D 404 61.321 -11.039 -18.585 1.00 17.63 C ANISOU 3264 CE1 PHE D 404 1984 2185 2531 -30 513 -438 C ATOM 3265 CZ PHE D 404 60.388 -11.449 -17.653 1.00 16.05 C ANISOU 3265 CZ PHE D 404 1812 1951 2336 -121 435 -426 C ATOM 3266 CE2 PHE D 404 59.342 -10.569 -17.262 1.00 17.50 C ANISOU 3266 CE2 PHE D 404 1951 2250 2448 -190 374 -393 C ATOM 3267 CD2 PHE D 404 59.283 -9.297 -17.818 1.00 13.88 C ANISOU 3267 CD2 PHE D 404 1438 1917 1919 -156 374 -367 C ATOM 3268 C PHE D 404 58.010 -8.031 -20.605 1.00 17.76 C ANISOU 3268 C PHE D 404 1967 2679 2102 -130 361 -459 C ATOM 3269 O PHE D 404 57.797 -9.247 -20.769 1.00 17.49 O ANISOU 3269 O PHE D 404 1986 2584 2073 -180 361 -559 O ATOM 3270 N SER D 405 57.052 -7.151 -20.315 1.00 18.09 N ANISOU 3270 N SER D 405 1951 2814 2110 -146 283 -420 N ATOM 3271 CA SER D 405 55.637 -7.523 -20.129 1.00 19.11 C ANISOU 3271 CA SER D 405 2039 3005 2216 -228 193 -487 C ATOM 3272 CB SER D 405 54.863 -6.332 -19.573 1.00 18.78 C ANISOU 3272 CB SER D 405 1906 3051 2179 -203 138 -418 C ATOM 3273 OG SER D 405 54.618 -5.349 -20.582 1.00 21.57 O ANISOU 3273 OG SER D 405 2269 3504 2423 -125.

96. 388 O ATOM 3274 C SER D 405 54.985 -8.034 -21.418 1.00 20.52 C ANISOU 3274 C SER D 405 2267 3260 2268 -254 138 -600 C ATOM 3275 O SER D 405 54.015 -8.769 -21.350 1.00 21.91 O ANISOU 3275 O SER D 405 2413 3456 2458 -351.

72. 689 O ATOM 3276 N GLN D 406 55.571 -7.670 -22.566 1.00 21.23 N ANISOU 3276 N GLN D 406 2441 3390 2236 -175 172 -596 N ATOM 3277 CA GLN D 406 55.127 -8.012 -23.897 1.00 22.62 C ANISOU 3277 CA GLN D 406 2703 3650 2242 -175 117 -699 C ATOM 3278 CB GLN D 406 55.211 -9.513 -24.125 1.00 23.49 C ANISOU 3278 CB GLN D 406 2891 3667 2369 -252 136 -852 C ATOM 3279 CG GLN D 406 56.607 -10.072 -23.936 1.00 22.07 C ANISOU 3279 CG GLN D 406 2774 3339 2271 -202 291 -842 C ATOM 3280 CD GLN D 406 56.648 -11.573 -24.102 1.00 23.20 C ANISOU 3280 CD GLN D 406 3007 3356 2451 -264 309 -996 C ATOM 3281 OE1 GLN D 406 55.795 -12.289 -23.567 1.00 21.91 O ANISOU 3281 OE1 GLN D 406 2815 3144 2366 -382 229 -1058 O ATOM 3282 NE2 GLN D 406 57.631 -12.062 -24.863 1.00 22.17 N ANISOU 3282 NE2 GLN D 406 2989 3163 2270 -186 426 -1061 N ATOM 3283 C GLN D 406 53.732 -7.462 -24.252 1.00 24.34 C ANISOU 3283 C GLN D 406 2853 4022 2375 -190 -45 -716 C ATOM 3284 O GLN D 406 53.072 -8.002 -25.126 1.00 26.35 O ANISOU 3284 O GLN D 406 3151 4349 2512 -230 -144 -835 O ATOM 3285 N GLU D 407 53.301 -6.400 -23.576 1.00 23.86 N ANISOU 3285 N GLU D 407 2683 4006 2376 -150 -80 -607 N ATOM 3286 CA GLU D 407 51.981 -5.796 -23.788 1.00 25.52 C ANISOU 3286 CA GLU D 407 2793 4360 2543 -134 -232 -609 C ATOM 3287 CB GLU D 407 51.717 -4.639 -22.799 1.00 24.44 C ANISOU 3287 CB GLU D 407 2544 4227 2515 -71 -223 -490 C ATOM 3288 CG GLU D 407 51.472 -5.060 -21.360 1.00 25.08 C ANISOU 3288 CG GLU D 407 2519 4243 2767 -157 -170 -504 C ATOM 3289 CD GLU D 407 50.431 -4.211 -20.650 1.00 25.93 C ANISOU 3289 CD GLU D 407 2476 4430 2946 -117 -219 -468 C ATOM 3290 OE1 GLU D 407 49.823 -3.328 -21.282 1.00 30.67 O ANISOU 3290 OE1 GLU D 407 3037 5131 3485 -17 -316 -436 O ATOM 3291 OE2 GLU D 407 50.193 -4.445 -19.455 1.00 24.61 O ANISOU 3291 OE2 GLU D 407 2235 4224 2892 -177 -157 -471 O ATOM 3292 C GLU D 407 51.805 -5.244 -25.195 1.00 26.98 C ANISOU 3292 C GLU D 407 3072 4661 2517 -44 -322 -598 C ATOM 3293 O GLU D 407 52.719 -4.653 -25.768 1.00 26.51 O ANISOU 3293 O GLU D 407 3136 4577 235.

43. 236 -508 O ATOM 3294 N ASP D 408 50.596 -5.404 -25.710 1.00 29.10 N ANISOU 3294 N ASP D 408 3273 5062 2720 -68 -498 -681 N ATOM 3295 CA ASP D 408 50.199 -4.853 -27.013 1.00 31.78 C ANISOU 3295 CA ASP D 408 3697 5539 283.

27. 637 -666 C ATOM 3296 CB ASP D 408 48.762 -5.265 -27.372 1.00 34.18 C ANISOU 3296 CB ASP D 408 3873 5992 3124 -31 -866 -792 C ATOM 3297 CG ASP D 408 48.348 -4.814 -28.781 1.00 39.52 C ANISOU 3297 CG ASP D 408 4655 6821 353.

70. 1048 -789 C ATOM 3298 OD1 ASP D 408 49.101 -5.101 -29.741 1.00 40.65 O ANISOU 3298 OD1 ASP D 408 5022 6953 346.

91. 999 -816 O ATOM 3299 OD2 ASP D 408 47.267 -4.173 -28.920 1.00 42.45 O ANISOU 3299 OD2 ASP D 408 4889 7328 3911 139 -1240 -758 O ATOM 3300 C ASP D 408 50.353 -3.342 -27.114 1.00 30.90 C ANISOU 3300 C ASP D 408 3607 5449 2686 185 -631 -478 C ATOM 3301 O ASP D 408 50.746 -2.852 -28.164 1.00 32.78 O ANISOU 3301 O ASP D 408 4008 5725 2721 275 -638 -408 O ATOM 3302 N ACYS D 409 50.067 -2.594 -26.052 0.50 29.14 N ANISOU 3302 N ACYS D 409 3243 5189 2642 219 -609 -394 N ATOM 3303 N BCYS D 409 50.023 -2.637 -26.028 0.50 29.40 N ANISOU 3303 N BCYS D 409 3268 5224 2679 214 -613 -401 N ATOM 3304 CA ACYS D 409 50.211 -1.138 -26.143 0.50 29.02 C ANISOU 3304 CA ACYS D 409 3266 5159 2603 370 -605 -222 C ATOM 3305 CA BCYS D 409 50.202 -1.188 -25.910 0.50 29.33 C ANISOU 3305 CA BCYS D 409 3279 5184 2680 356 -592 -230 C ATOM 3306 CB ACYS D 409 49.420 -0.405 -25.050 0.50 28.83 C ANISOU 3306 CB ACYS D 409 3056 5130 2766 418 -640 -186 C ATOM 3307 CB BCYS D 409 49.874 -0.714 -24.481 0.50 28.22 C ANISOU 3307 CB BCYS D 409 2976 4982 2765 357 -546 -204 C ATOM 3308 SG ACYS D 409 50.276 -0.105 -23.502 0.50 27.27 S ANISOU 3308 SG ACYS D 409 2828 4756 2776 378 -445 -139 S ATOM 3309 SG BCYS D 409 48.105 -0.436 -24.090 0.50 33.35 S ANISOU 3309 SG BCYS D 409 3379 5779 3515 404 -720 -257 S ATOM 3310 C ACYS D 409 51.667 -0.658 -26.204 0.50 27.74 C ANISOU 3310 C ACYS D 409 3260 4860 2420 395 -416 -104 C ATOM 3311 C BCYS D 409 51.624 -0.756 -26.258 0.50 28.09 C ANISOU 3311 C BCYS D 409 3304 4913 2455 389 -423 -117 C ATOM 3312 O ACYS D 409 51.933 0.433 -26.730 0.50 28.22 O ANISOU 3312 O ACYS D 409 3420 4902 2398 505 -407 42 O ATOM 3313 O BCYS D 409 51.824 0.197 -27.026 0.50 28.90 O ANISOU 3313 O BCYS D 409 3525 5025 2431 499 -434 14 O ATOM 3314 N MSE D 410 52.594 -1.466 -25.672 1.00 25.88 N ANISOU 3314 N MSE D 410 3037 4523 2272 295 -268 -161 N ATOM 3315 CA MSE D 410 54.024 -1.213 -25.835 1.00 24.44 C ANISOU 3315 CA MSE D 410 2971 4231 2082 304 -88 -74 C ATOM 3316 CB MSE D 410 54.833 -2.065 -24.854 1.00 22.88 C ANISOU 3316 CB MSE D 410 2718 3922 2054 20.

32. 139 C ATOM 3317 CG MSE D 410 56.350 -1.955 -24.998 1.00 21.58 C ANISOU 3317 CG MSE D 410 2626 3656 1917 211 213 -70 C ATOM 3318 SE MSE D 410 57.152 -3.307 -26.167 0.90 25.86 SE ANISOU 3318 SE MSE D 410 3301 4215 2311 188 331 -187 SE ATOM 3319 CE MSE D 410 56.323 -4.892 -25.393 1.00 24.10 C ANISOU 3319 CE MSE D 410 2993 3974 2189 79 226 -383 C ATOM 3320 C MSE D 410 54.468 -1.456 -27.290 1.00 26.13 C ANISOU 3320 C MSE D 410 3363 4505 2058 335 -51 -73 C ATOM 3321 O MSE D 410 55.180 -0.626 -27.871 1.00 26.11 O ANISOU 3321 O MSE D 410 3474 4473 1973 398 47 65 O ATOM 3322 N ILE D 411 54.017 -2.573 -27.865 1.00 26.59 N ANISOU 3322 N ILE D 411 3456 4644 2004 284 -125 -229 N ATOM 3323 CA ILE D 411 54.312 -2.938 -29.242 1.00 28.85 C ANISOU 3323 CA ILE D 411 3929 5002 2031 313 -103 -269 C ATOM 3324 CB ILE D 411 53.870 -4.398 -29.528 1.00 29.45 C ANISOU 3324 CB ILE D 411 4020 5117 2054 221 -180 -493 C ATOM 3325 CG1 ILE D 411 54.922 -5.354 -28.950 1.00 30.86 C ANISOU 3325 CG1 ILE D 411 4192 5151 2384 15.

9. 568 C ATOM 3326 CD1 ILE D 411 54.414 -6.711 -28.627 1.00 33.71 C ANISOU 3326 CD1 ILE D 411 4508 5477 282.

40. 62 -761 C ATOM 3327 CG2 ILE D 411 53.748 -4.648 -31.007 1.00 32.12 C ANISOU 3327 CG2 ILE D 411 4558 5571 2076 263 -237 -560 C ATOM 3328 C ILE D 411 53.726 -1.918 -30.235 1.00 30.57 C ANISOU 3328 C ILE D 411 4252 5336 2025 427 -227 -151 C ATOM 3329 O ILE D 411 54.376 -1.536 -31.219 1.00 31.47 O ANISOU 3329 O ILE D 411 4553 5470 1935 489 -128 -62 O ATOM 3330 N LYS D 412 52.501 -1.477 -29.956 1.00 30.42 N ANISOU 3330 N LYS D 412 4112 5395 2052 462 -436 -143 N ATOM 3331 CA LYS D 412 51.861 -0.437 -30.741 1.00 32.14 C ANISOU 3331 CA LYS D 412 4405 5709 2097 595 -584 -13 C ATOM 3332 CB LYS D 412 50.356 -0.417 -30.473 1.00 32.55 C ANISOU 3332 CB LYS D 412 4273 5878 2215 618 -846 -83 C ATOM 3333 CG LYS D 412 49.618 -1.672 -30.980 1.00 35.49 C ANISOU 3333 CG LYS D 412 4615 6379 2489 522 -1011 -302 C ATOM 3334 CD LYS D 412 49.784 -1.869 -32.495 1.00 37.96 C ANISOU 3334 CD LYS D 412 5179 6799 2444 570 -1080 -323 C ATOM 3335 CE LYS D 412 48.933 -3.010 -33.017 1.00 41.23 C ANISOU 3335 CE LYS D 412 5565 7342 2760 474 -1290 -557 C ATOM 3336 NZ LYS D 412 49.410 -4.347 -32.577 1.00 40.94 N ANISOU 3336 NZ LYS D 412 5511 7204 2841 307 -1155 -748 N ATOM 3337 C LYS D 412 52.488 0.954 -30.564 1.00 31.37 C ANISOU 3337 C LYS D 412 4368 5501 2052 689 -464 219 C ATOM 3338 O LYS D 412 52.263 1.832 -31.384 1.00 34.17 O ANISOU 3338 O LYS D 412 4853 5899 2228 808 -535 364 O ATOM 3339 N ALA D 413 53.283 1.145 -29.513 1.00 28.83 N ANISOU 3339 N ALA D 413 3961 5027 1966 633 -291 254 N ATOM 3340 CA ALA D 413 54.009 2.413 -29.275 1.00 28.38 C ANISOU 3340 CA ALA D 413 3958 4834 1993 687 -162 453 C ATOM 3341 CB ALA D 413 54.311 2.582 -27.805 1.00 25.93 C ANISOU 3341 CB ALA D 413 3482 4390 1981 626 -91 433 C ATOM 3342 C ALA D 413 55.295 2.553 -30.097 1.00 29.23 C ANISOU 3342 C ALA D 413 4248 4891 1969 672 54 557 C ATOM 3343 O ALA D 413 55.935 3.610 -30.084 1.00 29.28 O ANISOU 3343 O ALA D 413 4316 4781 2026 698 170 734 O ATOM 3344 N VAL D 414 55.681 1.491 -30.803 1.00 29.64 N ANISOU 3344 N VAL D 414 4382 5018 1860 624 122 442 N ATOM 3345 CA VAL D 414 56.838 1.555 -31.696 1.00 31.53 C ANISOU 3345 CA VAL D 414 4796 5239 1947 622 349 527 C ATOM 3346 CB VAL D 414 57.244 0.153 -32.204 1.00 31.72 C ANISOU 3346 CB VAL D 414 4872 5330 1851 568 433 337 C ATOM 3347 CG1 VAL D 414 58.299 0.242 -33.322 1.00 32.64 C ANISOU 3347 CG1 VAL D 414 5189 5463 1751 592 677 419 C ATOM 3348 CG2 VAL D 414 57.755 -0.679 -31.067 1.00 26.96 C ANISOU 3348 CG2 VAL D 414 4084 4628 1532 474 509 207 C ATOM 3349 C VAL D 414 56.567 2.486 -32.871 1.00 34.97 C ANISOU 3349 C VAL D 414 5447 5737 2103 730 311 706 C ATOM 3350 O VAL D 414 55.529 2.404 -33.514 1.00 37.43 O ANISOU 3350 O VAL D 414 5833 6183 2206 804 94 673 O ATOM 3351 N ARG D 415 57.504 3.384 -33.133 1.00 37.13 N ANISOU 3351 N ARG D 415 5819 5909 2380 735 517 905 N ATOM 3352 CA ARG D 415 57.422 4.265 -34.293 1.00 41.20 C ANISOU 3352 CA ARG D 415 6579 6461 2613 830 529 1110 C ATOM 3353 CB ARG D 415 57.470 5.732 -33.856 1.00 41.42 C ANISOU 3353 CB ARG D 415 6605 6324 2807 867 539 1341 C ATOM 3354 CG ARG D 415 56.268 6.184 -33.006 1.00 40.12 C ANISOU 3354 CG ARG D 415 6292 6136 2814 940 267 1312 C ATOM 3355 CD ARG D 415 54.948 6.139 -33.791 1.00 40.78 C ANISOU 3355 CD ARG D 415 6465 6391 2638 1079 -17 1301 C ATOM 3356 NE ARG D 415 53.810 6.480 -32.938 1.00 40.08 N ANISOU 3356 NE ARG D 415 6189 6295 2746 1151 -253 1252 N ATOM 3357 CZ ARG D 415 53.013 5.596 -32.344 1.00 38.46 C ANISOU 3357 CZ ARG D 415 5779 6195 2639 1117 -410 1034 C ATOM 3358 NH1 ARG D 415 53.202 4.298 -32.529 1.00 38.97 N ANISOU 3358 NH1 ARG D 415 5819 6364 2626 1012 -379 843 N ATOM 3359 NH2 ARG D 415 52.011 6.011 -31.573 1.00 36.41 N ANISOU 3359 NH2 ARG D 415 5342 5928 2563 1190 -586 1008 N ATOM 3360 C ARG D 415 58.551 3.952 -35.281 1.00 43.98 C ANISOU 3360 C ARG D 415 7110 6845 2756 796 815 1153 C ATOM 3361 O ARG D 415 59.724 3.892 -34.899 1.00 43.78 O ANISOU 3361 O ARG D 415 6999 6716 2919 706 1074 1170 O ATOM 3362 N GLY D 416 58.191 3.744 -36.545 1.00 47.07 N ANISOU 3362 N GLY D 416 7743 7387 2756 874 766 1163 N ATOM 3363 CA GLY D 416 59.167 3.367 -37.555 1.00 50.12 C ANISOU 3363 CA GLY D 416 8322 7829 2894 856 1047 1180 C ATOM 3364 C GLY D 416 59.585 1.904 -37.482 1.00 49.71 C ANISOU 3364 C GLY D 416 8192 7833 2861 793 1140 902 C ATOM 3365 O GLY D 416 59.098 1.128 -36.639 1.00 47.48 O ANISOU 3365 O GLY D 416 7713 7542 2783 750 976 701 O ATOM 3366 N ASP D 417 60.483 1.527 -38.386 1.00 52.34 N ANISOU 3366 N ASP D 417 8692 8219 2976 793 1417 896 N ATOM 3367 CA ASP D 417 60.963 0.150 -38.487 1.00 52.48 C ANISOU 3367 CA ASP D 417 8681 8279 2981 761 1539 635 C ATOM 3368 CB ASP D 417 61.397 -0.171 -39.931 1.00 56.31 C ANISOU 3368 CB ASP D 417 9473 8894 3029 820 1741 619 C ATOM 3369 CG ASP D 417 60.213 -0.435 -40.865 1.00 59.32 C ANISOU 3369 CG ASP D 417 10103 9446 2990 899 1447 528 C ATOM 3370 OD1 ASP D 417 59.072 -0.585 -40.386 1.00 59.62 O ANISOU 3370 OD1 ASP D 417 10036 9508 3109 898 1092 434 O ATOM 3371 OD2 ASP D 417 60.426 -0.508 -42.095 1.00 65.27 O ANISOU 3371 OD2 ASP D 417 11157 10319 3324 961 1571 544 O ATOM 3372 C ASP D 417 62.098 -0.116 -37.495 1.00 49.99 C ANISOU 3372 C ASP D 417 8103 7818 3073 676 1773 604 C ATOM 3373 O ASP D 417 62.852 0.793 -37.130 1.00 49.00 O ANISOU 3373 O ASP D 417 7885 7587 3145 634 1948 804 O ATOM 3374 N LEU D 418 62.205 -1.370 -37.064 1.00 48.76 N ANISOU 3374 N LEU D 418 7831 7652 3045 649 1760 353 N ATOM 3375 CA LEU D 418 63.263 -1.792 -36.159 1.00 47.10 C ANISOU 3375 CA LEU D 418 7377 7317 3201 592 1951 302 C ATOM 3376 CB LEU D 418 62.671 -2.523 -34.951 1.00 43.74 C ANISOU 3376 CB LEU D 418 6747 6820 3051 545 1712 135 C ATOM 3377 CG LEU D 418 61.641 -1.770 -34.088 1.00 41.30 C ANISOU 3377 CG LEU D 418 6331 6480 2881 518 1426 222 C ATOM 3378 CD1 LEU D 418 61.103 -2.653 -32.963 1.00 38.43 C ANISOU 3378 CD1 LEU D 418 5787 6060 2756 466 1240 45 C ATOM 3379 CD2 LEU D 418 62.198 -0.471 -33.502 1.00 40.54 C ANISOU 3379 CD2 LEU D 418 6125 6279 2999 488 1516 456 C ATOM 3380 C LEU D 418 64.314 -2.643 -36.873 1.00 49.82 C ANISOU 3380 C LEU D 418 7792 7692 3447 625 2264 186 C ATOM 3381 O LEU D 418 64.020 -3.727 -37.397 1.00 50.62 O ANISOU 3381 O LEU D 418 8020 7854 3358 665 2228 -37 O ATOM 3382 N ASN D 419 65.543 -2.131 -36.890 1.00 51.58 N ANISOU 3382 N ASN D 419 7923 7863 3811 605 2578 331 N ATOM 3383 CA ASN D 419 66.641 -2.741 -37.637 1.00 55.38 C ANISOU 3383 CA ASN D 419 8453 8383 4204 650 2935 258 C ATOM 3384 CB ASN D 419 66.810 -2.036 -38.993 1.00 59.00 C ANISOU 3384 CB ASN D 419 9195 8957 4265 688 3148 420 C ATOM 3385 CG ASN D 419 65.665 -2.308 -39.945 1.00 61.70 C ANISOU 3385 CG ASN D 419 9864 9436 4145 756 2933 329 C ATOM 3386 OD1 ASN D 419 65.411 -3.454 -40.327 1.00 65.31 O ANISOU 3386 OD1 ASN D 419 10428 9949 4440 806 2887 70 O ATOM 3387 ND2 ASN D 419 64.978 -1.249 -40.352 1.00 63.31 N ANISOU 3387 ND2 ASN D 419 10234 9687 4135 763 2791 539 N ATOM 3388 C ASN D 419 67.967 -2.719 -36.875 1.00 55.20 C ANISOU 3388 C ASN D 419 8127 8253 4594 607 3178 304 C ATOM 3389 O ASN D 419 69.023 -2.657 -37.482 1.00 57.94 O ANISOU 3389 O ASN D 419 8467 8629 4917 625 3529 357 O ATOM 3390 N PHE D 420 67.907 -2.779 -35.544 1.00 53.13 N ANISOU 3390 N PHE D 420 7606 7875 4704 552 2988 281 N ATOM 3391 CA PHE D 420 69.109 -2.716 -34.699 1.00 52.97 C ANISOU 3391 CA PHE D 420 7276 7755 5095 508 3151 324 C ATOM 3392 CB PHE D 420 68.768 -2.606 -33.210 1.00 49.23 C ANISOU 3392 CB PHE D 420 6582 7166 4956 444 2866 319 C ATOM 3393 CG PHE D 420 68.193 -1.287 -32.813 1.00 47.59 C ANISOU 3393 CG PHE D 420 6385 6920 4777 366 2702 511 C ATOM 3394 CD1 PHE D 420 66.832 -1.155 -32.549 1.00 44.55 C ANISOU 3394 CD1 PHE D 420 6113 6548 4267 372 2390 485 C ATOM 3395 CE1 PHE D 420 66.292 0.070 -32.189 1.00 42.45 C ANISOU 3395 CE1 PHE D 420 5858 6235 4036 326 2247 653 C ATOM 3396 CZ PHE D 420 67.108 1.173 -32.079 1.00 44.31 C ANISOU 3396 CZ PHE D 420 6013 6391 4434 255 2405 848 C ATOM 3397 CE2 PHE D 420 68.467 1.060 -32.333 1.00 47.66 C ANISOU 3397 CE2 PHE D 420 6314 6802 4991 223 2712 881 C ATOM 3398 CD2 PHE D 420 69.007 -0.170 -32.699 1.00 48.65 C ANISOU 3398 CD2 PHE D 420 6408 6994 5082 287 2863 713 C ATOM 3399 C PHE D 420 70.044 -3.885 -34.897 1.00 55.24 C ANISOU 3399 C PHE D 420 7475 8045 5470 588 3382 148 C ATOM 3400 O PHE D 420 69.616 -5.017 -35.139 1.00 55.65 O ANISOU 3400 O PHE D 420 7645 8113 5387 664 3310 -68 O ATOM 3401 N VAL D 421 71.326 -3.572 -34.740 1.00 57.63 N ANISOU 3401 N VAL D 421 7549 8317 6030 565 3651 242 N ATOM 3402 CA VAL D 421 72.446 -4.448 -35.036 1.00 60.77 C ANISOU 3402 CA VAL D 421 7821 8726 6542 654 3948 120 C ATOM 3403 CB VAL D 421 73.166 -3.930 -36.322 1.00 64.47 C ANISOU 3403 CB VAL D 421 8404 9304 6788 666 4360 236 C ATOM 3404 CG1 VAL D 421 74.630 -4.300 -36.367 1.00 67.05 C ANISOU 3404 CG1 VAL D 421 8458 9632 7386 714 4721 208 C ATOM 3405 CG2 VAL D 421 72.428 -4.388 -37.580 1.00 66.03 C ANISOU 3405 CG2 VAL D 421 8997 9617 6475 754 4400 126 C ATOM 3406 C VAL D 421 73.361 -4.471 -33.799 1.00 60.35 C ANISOU 3406 C VAL D 421 7378 8567 6985 619 3924 144 C ATOM 3407 O VAL D 421 73.403 -3.496 -33.045 1.00 58.87 O ANISOU 3407 O VAL D 421 7042 8323 7003 501 3800 305 O ATOM 3408 N ASN D 422 74.043 -5.593 -33.555 1.00 62.10 N ANISOU 3408 N ASN D 422 7446 8752 7397 728 4012 -23 N ATOM 3409 CA ASN D 422 75.069 -5.636 -32.502 1.00 62.56 C ANISOU 3409 CA ASN D 422 7120 8730 7918 718 4012 6 C ATOM 3410 CB ASN D 422 75.045 -6.970 -31.720 1.00 61.54 C ANISOU 3410 CB ASN D 422 6907 8505 7969 834 3835 -189 C ATOM 3411 CG ASN D 422 75.460 -8.203 -32.559 1.00 64.42 C ANISOU 3411 CG ASN D 422 7361 8885 8231 1012 4080 -391 C ATOM 3412 OD1 ASN D 422 75.195 -9.336 -32.147 1.00 63.87 O ANISOU 3412 OD1 ASN D 422 7329 8720 8219 1110 3933 -561 O ATOM 3413 ND2 ASN D 422 76.118 -7.995 -33.700 1.00 67.10 N ANISOU 3413 ND2 ASN D 422 7740 9330 8425 1055 4460 -372 N ATOM 3414 C ASN D 422 76.469 -5.287 -33.033 1.00 66.36 C ANISOU 3414 C ASN D 422 7376 9270 8567 724 4415 91 C ATOM 3415 O ASN D 422 76.626 -4.987 -34.223 1.00 69.23 O ANISOU 3415 O ASN D 422 7905 9734 8666 733 4718 140 O ATOM 3416 N ARG D 423 77.475 -5.324 -32.158 1.00 67.11 N ANISOU 3416 N ARG D 423 7093 9311 9095 719 4419 113 N ATOM 3417 CA ARG D 423 78.878 -5.054 -32.539 1.00 71.12 C ANISOU 3417 CA ARG D 423 7306 9875 9840 720 4794 183 C ATOM 3418 CB ARG D 423 79.805 -5.272 -31.338 1.00 70.83 C ANISOU 3418 CB ARG D 423 6839 9769 10305 731 4668 172 C ATOM 3419 CG ARG D 423 81.105 -4.524 -31.468 1.00 75.85 C ANISOU 3419 CG ARG D 423 7115 10456 11248 641 4957 306 C ATOM 3420 CD ARG D 423 82.094 -4.875 -30.379 1.00 78.88 C ANISOU 3420 CD ARG D 423 7053 10793 12126 681 4832 269 C ATOM 3421 NE ARG D 423 83.449 -4.480 -30.778 1.00 83.39 N ANISOU 3421 NE ARG D 423 7254 11442 12987 644 5197 346 N ATOM 3422 CZ ARG D 423 84.346 -3.929 -29.962 1.00 85.30 C ANISOU 3422 CZ ARG D 423 7077 11667 13667 531 5116 429 C ATOM 3423 NH1 ARG D 423 84.039 -3.684 -28.689 1.00 83.30 N ANISOU 3423 NH1 ARG D 423 6747 11320 13584 452 4676 442 N ATOM 3424 NH2 ARG D 423 85.547 -3.606 -30.420 1.00 88.44 N ANISOU 3424 NH2 ARG D 423 7128 12146 14328 490 5478 494 N ATOM 3425 C ARG D 423 79.401 -5.843 -33.761 1.00 74.67 C ANISOU 3425 C ARG D 423 7845 10417 10109 882 5200 61 C ATOM 3426 O ARG D 423 80.280 -5.369 -34.493 1.00 78.15 O ANISOU 3426 O ARG D 423 8167 10945 10580 855 5588 155 O ATOM 3427 N ALA D 424 78.849 -7.036 -33.971 1.00 74.34 N ANISOU 3427 N ALA D 424 8018 10348 9879 1042 5120 -153 N ATOM 3428 CA ALA D 424 79.275 -7.945 -35.036 1.00 77.50 C ANISOU 3428 CA ALA D 424 8532 10811 10104 1222 5468 -322 C ATOM 3429 CB ALA D 424 79.327 -9.375 -34.497 1.00 77.08 C ANISOU 3429 CB ALA D 424 8426 10642 10219 1410 5328 -554 C ATOM 3430 C ALA D 424 78.429 -7.881 -36.329 1.00 78.58 C ANISOU 3430 C ALA D 424 9131 11043 9682 1227 5589 -362 C ATOM 3431 O ALA D 424 78.708 -8.612 -37.287 1.00 81.61 O ANISOU 3431 O ALA D 424 9666 11484 9858 1375 5881 -520 O ATOM 3432 N ASN D 425 77.396 -7.032 -36.340 1.00 76.24 N ANISOU 3432 N ASN D 425 9062 10762 9143 1081 5352 -230 N ATOM 3433 CA ASN D 425 76.541 -6.773 -37.531 1.00 77.06 C ANISOU 3433 CA ASN D 425 9601 10971 8708 1070 5413 -224 C ATOM 3434 CB ASN D 425 77.382 -6.619 -38.817 1.00 81.53 C ANISOU 3434 CB ASN D 425 10245 11670 9062 1128 5927 -191 C ATOM 3435 CG ASN D 425 76.892 -5.487 -39.721 1.00 82.66 C ANISOU 3435 CG ASN D 425 10683 11919 8803 1017 6017 23 C ATOM 3436 OD1 ASN D 425 75.842 -4.884 -39.484 1.00 79.73 O ANISOU 3436 OD1 ASN D 425 10484 11524 8284 921 5681 122 O ATOM 3437 ND2 ASN D 425 77.670 -5.189 -40.763 1.00 87.19 N ANISOU 3437 ND2 ASN D 425 11314 12609 9204 1038 6484 104 N ATOM 3438 C ASN D 425 75.343 -7.727 -37.759 1.00 75.53 C ANISOU 3438 C ASN D 425 9745 10754 8199 1149 5142 -450 C ATOM 3439 O ASN D 425 74.857 -7.888 -38.889 1.00 77.60 O ANISOU 3439 O ASN D 425 10357 11113 8012 1196 5244 -527 O ATOM 3440 N GLN D 426 74.866 -8.349 -36.685 1.00 72.05 N ANISOU 3440 N GLN D 426 9203 10184 7987 1153 4795 -555 N ATOM 3441 CA GLN D 426 73.650 -9.164 -36.756 1.00 70.27 C ANISOU 3441 CA GLN D 426 9262 9919 7517 1181 4501 -748 C ATOM 3442 CB GLN D 426 73.803 -10.451 -35.941 1.00 69.42 C ANISOU 3442 CB GLN D 426 9024 9655 7697 1280 4372 -950 C ATOM 3443 CG GLN D 426 74.946 -11.353 -36.387 1.00 73.99 C ANISOU 3443 CG GLN D 426 9510 10209 8392 1461 4723 -1107 C ATOM 3444 CD GLN D 426 75.603 -12.085 -35.226 1.00 74.03 C ANISOU 3444 CD GLN D 426 9200 10055 8872 1543 4632 -1157 C ATOM 3445 OE1 GLN D 426 75.551 -11.640 -34.081 1.00 71.79 O ANISOU 3445 OE1 GLN D 426 8697 9713 8868 1449 4387 -1016 O ATOM 3446 NE2 GLN D 426 76.238 -13.210 -35.525 1.00 76.73 N ANISOU 3446 NE2 GLN D 426 9532 10324 9297 1733 4831 -1361 N ATOM 3447 C GLN D 426 72.469 -8.361 -36.228 1.00 66.34 C ANISOU 3447 C GLN D 426 8844 9421 6942 1033 4126 -613 C ATOM 3448 O GLN D 426 72.648 -7.428 -35.444 1.00 64.20 O ANISOU 3448 O GLN D 426 8361 9122 6912 930 4038 -414 O ATOM 3449 N ARG D 427 71.267 -8.715 -36.673 1.00 65.24 N ANISOU 3449 N ARG D 427 9004 9310 6472 1027 3906 -733 N ATOM 3450 CA ARG D 427 70.051 -8.191 -36.069 1.00 61.55 C ANISOU 3450 CA ARG D 427 8583 8831 5972 913 3523 -653 C ATOM 3451 CB ARG D 427 68.814 -8.575 -36.886 1.00 62.29 C ANISOU 3451 CB ARG D 427 9018 9000 5650 917 3336 -797 C ATOM 3452 CG ARG D 427 68.261 -7.481 -37.795 1.00 64.44 C ANISOU 3452 CG ARG D 427 9512 9421 5551 879 3327 -631 C ATOM 3453 CD ARG D 427 66.962 -7.945 -38.473 1.00 65.91 C ANISOU 3453 CD ARG D 427 10000 9683 5358 883 3067 -794 C ATOM 3454 NE ARG D 427 65.923 -8.303 -37.500 1.00 66.69 N ANISOU 3454 NE ARG D 427 10003 9701 5634 809 2687 -872 N ATOM 3455 CZ ARG D 427 64.760 -7.663 -37.349 1.00 67.25 C ANISOU 3455 CZ ARG D 427 10120 9829 5603 741 2381 -785 C ATOM 3456 NH1 ARG D 427 64.467 -6.631 -38.135 1.00 69.18 N ANISOU 3456 NH1 ARG D 427 10527 10201 5557 750 2385 -613 N ATOM 3457 NH2 ARG D 427 63.886 -8.059 -36.414 1.00 63.74 N ANISOU 3457 NH2 ARG D 427 9559 9311 5349 671 2080 -864 N ATOM 3458 C ARG D 427 69.909 -8.721 -34.642 1.00 57.19 C ANISOU 3458 C ARG D 427 7803 8128 5798 883 3273 -704 C ATOM 3459 O ARG D 427 70.103 -9.914 -34.377 1.00 57.69 O ANISOU 3459 O ARG D 427 7840 8092 5987 959 3269 -894 O ATOM 3460 N LEU D 428 69.595 -7.815 -33.724 1.00 52.80 N ANISOU 3460 N LEU D 428 7098 7547 5418 778 3076 -527 N ATOM 3461 CA LEU D 428 69.144 -8.185 -32.399 1.00 48.04 C ANISOU 3461 CA LEU D 428 6348 6827 5079 732 2792 -559 C ATOM 3462 CB LEU D 428 68.918 -6.930 -31.545 1.00 45.72 C ANISOU 3462 CB LEU D 428 5911 6527 4933 622 2636 -347 C ATOM 3463 CG LEU D 428 70.023 -5.875 -31.426 1.00 45.49 C ANISOU 3463 CG LEU D 428 5686 6505 5093 586 2834 -153 C ATOM 3464 CD1 LEU D 428 69.597 -4.802 -30.425 1.00 41.45 C ANISOU 3464 CD1 LEU D 428 5066 5948 4733 475 2612 4 C ATOM 3465 CD2 LEU D 428 71.353 -6.491 -31.016 1.00 45.37 C ANISOU 3465 CD2 LEU D 428 5422 6426 5391 651 3013 -200 C ATOM 3466 C LEU D 428 67.846 -8.982 -32.525 1.00 46.17 C ANISOU 3466 C LEU D 428 6321 6580 4642 717 2547 -732 C ATOM 3467 O LEU D 428 67.099 -8.802 -33.495 1.00 46.00 O ANISOU 3467 O LEU D 428 6533 6665 4279 710 2512 -766 O ATOM 3468 N ASN D 429 67.587 -9.863 -31.556 1.00 43.68 N ANISOU 3468 N ASN D 429 5922 6137 4538 708 2374 -834 N ATOM 3469 CA ASN D 429 66.288 -10.534 -31.500 1.00 42.36 C ANISOU 3469 CA ASN D 429 5910 5947 4237 654 2121 -976 C ATOM 3470 CB ASN D 429 66.290 -11.755 -30.550 1.00 41.80 C ANISOU 3470 CB ASN D 429 5766 5699 4415 662 2019 -1102 C ATOM 3471 CG ASN D 429 66.394 -11.396 -29.062 1.00 40.02 C ANISOU 3471 CG ASN D 429 5314 5396 4495 608 1878 -956 C ATOM 3472 OD1 ASN D 429 66.177 -10.270 -28.644 1.00 40.08 O ANISOU 3472 OD1 ASN D 429 5232 5473 4524 542 1798 -792 O ATOM 3473 ND2 ASN D 429 66.713 -12.395 -28.251 1.00 41.75 N ANISOU 3473 ND2 ASN D 429 5463 5458 4943 644 1840 -1024 N ATOM 3474 C ASN D 429 65.147 -9.524 -31.230 1.00 39.73 C ANISOU 3474 C ASN D 429 5590 5701 3805 548 1883 -849 C ATOM 3475 O ASN D 429 65.412 -8.410 -30.755 1.00 37.87 O ANISOU 3475 O ASN D 429 5221 5490 3678 516 1887 -655 O ATOM 3476 N PRO D 430 63.894 -9.878 -31.600 1.00 39.17 N ANISOU 3476 N PRO D 430 5679 5677 3529 497 1681 -965 N ATOM 3477 CA PRO D 430 62.734 -8.984 -31.432 1.00 37.02 C ANISOU 3477 CA PRO D 430 5410 5497 3159 420 1451 -863 C ATOM 3478 CB PRO D 430 61.553 -9.913 -31.669 1.00 37.39 C ANISOU 3478 CB PRO D 430 5577 5550 3079 364 1242 -1062 C ATOM 3479 CG PRO D 430 62.081 -10.877 -32.687 1.00 40.79 C ANISOU 3479 CG PRO D 430 6190 5964 3346 432 1404 -1251 C ATOM 3480 CD PRO D 430 63.507 -11.136 -32.276 1.00 40.91 C ANISOU 3480 CD PRO D 430 6084 5865 3594 513 1659 -1213 C ATOM 3481 C PRO D 430 62.622 -8.261 -30.087 1.00 33.75 C ANISOU 3481 C PRO D 430 4783 5029 3011 363 1338 -704 C ATOM 3482 O PRO D 430 62.364 -7.059 -30.075 1.00 33.39 O ANISOU 3482 O PRO D 430 4712 5054 2922 350 1292 -543 O ATOM 3483 N MSE D 431 62.848 -8.958 -28.971 1.00 31.86 N ANISOU 3483 N MSE D 431 4412 4658 3035 338 1298 -746 N ATOM 3484 CA MSE D 431 62.743 -8.348 -27.632 1.00 28.73 C ANISOU 3484 CA MSE D 431 3838 4212 2866 286 1187 -615 C ATOM 3485 CB MSE D 431 62.750 -9.420 -26.522 1.00 27.66 C ANISOU 3485 CB MSE D 431 3625 3936 2949 257 1113 -693 C ATOM 3486 CG MSE D 431 61.493 -10.315 -26.470 1.00 27.35 C ANISOU 3486 CG MSE D 431 3673 3880 2840 179 946 -835 C ATOM 3487 SE MSE D 431 59.849 -9.332 -26.102 0.90 31.03 SE ANISOU 3487 SE MSE D 431 4095 4475 3220 81 709 -763 SE ATOM 3488 CE MSE D 431 60.279 -8.893 -24.268 1.00 22.81 C ANISOU 3488 CE MSE D 431 2865 3332 2469 58 684 -614 C ATOM 3489 C MSE D 431 63.805 -7.287 -27.358 1.00 28.34 C ANISOU 3489 C MSE D 431 3663 4159 2948 313 1319 -441 C ATOM 3490 O MSE D 431 63.527 -6.285 -26.719 1.00 26.80 O ANISOU 3490 O MSE D 431 3388 3975 2822 271 1226 -314 O ATOM 3491 N HIS D 432 65.023 -7.514 -27.840 1.00 30.47 N ANISOU 3491 N HIS D 432 3907 4407 3264 380 1540 -445 N ATOM 3492 CA HIS D 432 66.103 -6.525 -27.751 1.00 31.28 C ANISOU 3492 CA HIS D 432 3877 4513 3497 388 1692 -287 C ATOM 3493 CB HIS D 432 67.466 -7.225 -27.838 1.00 32.69 C ANISOU 3493 CB HIS D 432 3946 4634 3841 464 1905 -335 C ATOM 3494 CG HIS D 432 67.822 -7.950 -26.579 1.00 33.74 C ANISOU 3494 CG HIS D 432 3924 4646 4251 475 1799 -373 C ATOM 3495 ND1 HIS D 432 67.295 -9.184 -26.261 1.00 34.66 N ANISOU 3495 ND1 HIS D 432 4117 4682 4371 496 1690 -514 N ATOM 3496 CE1 HIS D 432 67.748 -9.561 -25.077 1.00 34.47 C ANISOU 3496 CE1 HIS D 432 3947 4553 4597 508 1603 -490 C ATOM 3497 NE2 HIS D 432 68.534 -8.608 -24.606 1.00 33.88 N ANISOU 3497 NE2 HIS D 432 3695 4499 4680 491 1632 -354 N ATOM 3498 CD2 HIS D 432 68.587 -7.583 -25.521 1.00 33.50 C ANISOU 3498 CD2 HIS D 432 3682 4555 4490 461 1760 -279 C ATOM 3499 C HIS D 432 65.961 -5.388 -28.772 1.00 32.02 C ANISOU 3499 C HIS D 432 4081 4712 3373 380 1782 -166 C ATOM 3500 O HIS D 432 66.410 -4.265 -28.541 1.00 31.60 O ANISOU 3500 O HIS D 432 3939 4650 3418 343 1831 -4 O ATOM 3501 N GLN D 433 65.317 -5.703 -29.889 1.00 33.25 N ANISOU 3501 N GLN D 433 4447 4957 3229 412 1790 -247 N ATOM 3502 CA GLN D 433 64.893 -4.737 -30.897 1.00 34.81 C ANISOU 3502 CA GLN D 433 4806 5264 3155 417 1816 -136 C ATOM 3503 CB GLN D 433 64.124 -5.526 -31.969 1.00 37.14 C ANISOU 3503 CB GLN D 433 5332 5652 3127 458 1766 -297 C ATOM 3504 CG GLN D 433 64.229 -5.159 -33.425 1.00 40.17 C ANISOU 3504 CG GLN D 433 5942 6157 3166 513 1917 -256 C ATOM 3505 CD GLN D 433 65.636 -4.990 -33.941 1.00 42.73 C ANISOU 3505 CD GLN D 433 6242 6477 3518 553 2269 -184 C ATOM 3506 OE1 GLN D 433 66.081 -3.868 -34.122 1.00 42.34 O ANISOU 3506 OE1 GLN D 433 6173 6441 3473 532 2393 22 O ATOM 3507 NE2 GLN D 433 66.331 -6.095 -34.227 1.00 44.78 N ANISOU 3507 NE2 GLN D 433 6506 6712 3797 612 2445 -355 N ATOM 3508 C GLN D 433 63.985 -3.705 -30.188 1.00 33.00 C ANISOU 3508 C GLN D 433 4532 5029 2979 363 1591 -12 C ATOM 3509 O GLN D 433 64.238 -2.508 -30.244 1.00 33.66 O ANISOU 3509 O GLN D 433 4602 5106 3081 347 1644 167 O ATOM 3510 N LEU D 434 62.956 -4.188 -29.488 1.00 30.54 N ANISOU 3510 N LEU D 434 4191 4705 2709 334 1355 -111 N ATOM 3511 CA LEU D 434 62.019 -3.349 -28.723 1.00 28.54 C ANISOU 3511 CA LEU D 434 3877 4447 2519 298 1147 -27 C ATOM 3512 CB LEU D 434 60.860 -4.193 -28.170 1.00 26.57 C ANISOU 3512 CB LEU D 434 3605 4209 2281 263 932 -173 C ATOM 3513 CG LEU D 434 59.960 -4.841 -29.225 1.00 28.19 C ANISOU 3513 CG LEU D 434 3969 4522 2219 278 838 -304 C ATOM 3514 CD1 LEU D 434 59.179 -6.004 -28.622 1.00 25.09 C ANISOU 3514 CD1 LEU D 434 3526 4099 1908 213 690 -476 C ATOM 3515 CD2 LEU D 434 59.035 -3.808 -29.879 1.00 26.55 C ANISOU 3515 CD2 LEU D 434 3849 4430 1809 316 706 -203 C ATOM 3516 C LEU D 434 62.664 -2.581 -27.568 1.00 27.04 C ANISOU 3516 C LEU D 434 3514 4152 2609 258 1167 91 C ATOM 3517 O LEU D 434 62.423 -1.387 -27.390 1.00 25.53 O

ANISOU 3517 O LEU D 434 3318 3948 2436 251 1119 227 O

ATOM 3518 N LEU D 435 63.462 -3.285 -26.775 1.00 26.54 N

ANISOU 3518 N LEU D 435 3318 4005 2760 239 1220 31 N

ATOM 3519 CA LEU D 435 64.256 -2.688 -25.702 1.00 26.16 C

ANISOU 3519 CA LEU D 435 3103 3862 2975 200 1234 119 C

ATOM 3520 CB LEU D 435 65.092 -3.789 -25.043 1.00 25.47 C

ANISOU 3520 CB LEU D 435 2895 3705 3077 208 1276 27 C

ATOM 3521 CG LEU D 435 65.725 -3.556 -23.679 1.00 24.89 C

ANISOU 3521 CG LEU D 435 2647 3540 3271 171 1207 70 C

ATOM 3522 CD1 LEU D 435 64.682 -3.442 -22.582 1.00 20.95 C

ANISOU 3522 CD1 LEU D 435 2152 3019 2787 132 993 52 C

ATOM 3523 CD2 LEU D 435 66.673 -4.719 -23.380 1.00 26.46 C

ANISOU 3523 CD2 LEU D 435 2748 3683 3624 217 1274 -9 C

ATOM 3524 C LEU D 435 65.136 -1.488 -26.142 1.00 27.72 C

ANISOU 3524 C LEU D 435 3277 4043 3215 183 1392 280 C

ATOM 3525 O LEU D 435 65.062 -0.432 -25.523 1.00 27.64 O

ANISOU 3525 O LEU D 435 3216 3976 3311 140 1321 381 O

ATOM 3526 N ARG D 436 65.954 -1.635 -27.191 1.00 30.12 N

ANISOU 3526 N ARG D 436 3621 4384 3438 211 1617 302 N

ATOM 3527 CA ARG D 436 66.820 -0.532 -27.661 1.00 32.34 C

ANISOU 3527 CA ARG D 436 3877 4644 3766 175 1803 469 C

ATOM 3528 CB ARG D 436 67.825 -0.970 -28.749 1.00 34.74 C

ANISOU 3528 CB ARG D 436 4200 5003 3997 211 2095 466 C

ATOM 3529 CG ARG D 436 68.788 -2.119 -28.428 1.00 38.82 C

ANISOU 3529 CG ARG D 436 4552 5499 4700 249 2201 339 C

ATOM 3530 CD ARG D 436 69.651 -1.978 -27.166 1.00 45.47 C

ANISOU 3530 CD ARG D 436 5125 6244 5908 197 2148 361 C

ATOM 3531 NE ARG D 436 70.087 -3.302 -26.682 1.00 50.46 N

ANISOU 3531 NE ARG D 436 5647 6850 6677 269 2131 214 N

ATOM 3532 CZ ARG D 436 70.128 -3.695 -25.402 1.00 51.20 C

ANISOU 3532 CZ ARG D 436 5607 6868 6978 261 1938 168 C

ATOM 3533 NH1 ARG D 436 69.776 -2.873 -24.420 1.00 50.06 N

ANISOU 3533 NH1 ARG D 436 5415 6676 6930 180 1748 238 N

ATOM 3534 NH2 ARG D 436 70.533 -4.928 -25.097 1.00 53.27 N

ANISOU 3534 NH2 ARG D 436 5801 7095 7346 344 1938 52 N

ATOM 3535 C ARG D 436 66.028 0.663 -28.204 1.00 32.58 C

ANISOU 3535 C ARG D 436 4070 4692 3616 169 1749 610 C

ATOM 3536 O ARG D 436 66.482 1.801 -28.113 1.00 33.26 O

ANISOU 3536 O ARG D 436 4125 4705 3810 112 1815 763 O

ATOM 3537 N HIS D 437 64.874 0.396 -28.813 1.00 32.38 N

ANISOU 3537 N HIS D 437 4222 4757 3325 230 1627 560 N

ATOM 3538 CA HIS D 437 63.992 1.447 -29.316 1.00 32.23 C

ANISOU 3538 CA HIS D 437 4358 4760 3127 257 1533 689 C

ATOM 3539 CB HIS D 437 62.776 0.835 -29.996 1.00 32.33 C

ANISOU 3539 CB HIS D 437 4528 4902 2856 329 1377 588 C

ATOM 3540 CG HIS D 437 61.792 1.845 -30.505 1.00 32.58 C

ANISOU 3540 CG HIS D 437 4705 4969 2705 384 1241 716 C

ATOM 3541 ND1 HIS D 437 62.005 2.587 -31.652 1.00 33.44 N

ANISOU 3541 ND1 HIS D 437 5004 5109 2594 423 1364 882 N

ATOM 3542 CE1 HIS D 437 60.975 3.389 -31.850 1.00 32.84 C

ANISOU 3542 CE1 HIS D 437 5028 5050 2399 489 1178 978 C

ATOM 3543 NE2 HIS D 437 60.100 3.192 -30.877 1.00 31.03 N

ANISOU 3543 NE2 HIS D 437 4663 4812 2316 493 955 869 N

ATOM 3544 CD2 HIS D 437 60.589 2.233 -30.023 1.00 28.67 C

ANISOU 3544 CD2 HIS D 437 4193 4482 2217 419 996 711 C

ATOM 3545 C HIS D 437 63.529 2.367 -28.191 1.00 31.00 C

ANISOU 3545 C HIS D 437 4111 4501 3166 224 1360 750 C

ATOM 3546 O HIS D 437 63.642 3.606 -28.303 1.00 31.79 O

ANISOU 3546 O HIS D 437 4259 4524 3297 208 1393 917 O

ATOM 3547 N PHE D 438 63.015 1.763 -27.119 1.00 28.21 N

ANISOU 3547 N PHE D 438 3643 4136 2938 213 1191 616 N

ATOM 3548 CA PHE D 438 62.438 2.523 -26.020 1.00 27.04 C

ANISOU 3548 CA PHE D 438 3427 3908 2940 198 1026 640 C

ATOM 3549 CB PHE D 438 61.377 1.704 -25.284 1.00 24.52 C

ANISOU 3549 CB PHE D 438 3057 3643 2616 215 836 490 C ATOM 3550 CG PHE D 438 60.176 1.379 -26.140 1.00 23.90 C ANISOU 3550 CG PHE D 438 3093 3692 2294 282 727 446 C ATOM 3551 CD1 PHE D 438 59.391 2.399 -26.676 1.00 23.65 C ANISOU 3551 CD1 PHE D 438 3161 3687 2138 351 643 555 C ATOM 3552 CE1 PHE D 438 58.280 2.110 -27.459 1.00 24.54 C ANISOU 3552 CE1 PHE D 438 3360 3932 2032 417 509 512 C ATOM 3553 CZ PHE D 438 57.941 0.772 -27.715 1.00 25.28 C ANISOU 3553 CZ PHE D 438 3448 4125 2034 392 465 343 C ATOM 3554 CE2 PHE D 438 58.734 -0.261 -27.196 1.00 23.25 C ANISOU 3554 CE2 PHE D 438 3113 3818 1903 320 569 233 C ATOM 3555 CD2 PHE D 438 59.836 0.052 -26.416 1.00 22.04 C ANISOU 3555 CD2 PHE D 438 2868 3543 1964 276 694 292 C ATOM 3556 C PHE D 438 63.462 3.158 -25.072 1.00 27.33 C ANISOU 3556 C PHE D 438 3326 3806 3251 116 1082 694 C ATOM 3557 O PHE D 438 63.182 4.188 -24.467 1.00 27.54 O ANISOU 3557 O PHE D 438 3351 3740 3375 103 998 758 O ATOM 3558 N GLN D 439 64.639 2.551 -24.975 1.00 27.93 N ANISOU 3558 N GLN D 439 3289 3867 3455 69 1218 661 N ATOM 3559 CA GLN D 439 65.790 3.129 -24.318 1.00 28.89 C ANISOU 3559 CA GLN D 439 3266 3877 3835 -18 1287 717 C ATOM 3560 CB GLN D 439 66.920 2.062 -24.200 1.00 29.69 C ANISOU 3560 CB GLN D 439 3213 4002 4067 -32 1401 637 C ATOM 3561 CG GLN D 439 66.621 0.950 -23.141 1.00 26.15 C ANISOU 3561 CG GLN D 439 2686 3563 3686 -6 1239 487 C ATOM 3562 CD GLN D 439 67.662 -0.160 -23.094 1.00 28.79 C ANISOU 3562 CD GLN D 439 2888 3909 4142 14 1338 414 C ATOM 3563 OE1 GLN D 439 68.317 -0.497 -24.104 1.00 32.54 O ANISOU 3563 OE1 GLN D 439 3363 4430 4572 44 1542 425 O ATOM 3564 NE2 GLN D 439 67.822 -0.748 -21.912 1.00 28.30 N ANISOU 3564 NE2 GLN D 439 2720 3805 4230 12 1198 340 N ATOM 3565 C GLN D 439 66.284 4.385 -25.045 1.00 31.94 C ANISOU 3565 C GLN D 439 3715 4193 4229 -65 1434 895 C ATOM 3566 O GLN D 439 66.781 5.320 -24.410 1.00 32.63 O ANISOU 3566 O GLN D 439 3727 4152 4519 -149 1421 959 O ATOM 3567 N LYS D 440 66.162 4.415 -26.374 1.00 34.31 N ANISOU 3567 N LYS D 440 4167 4567 4301 -18 1575 976 N ATOM 3568 CA LYS D 440 66.529 5.601 -27.135 1.00 37.03 C ANISOU 3568 CA LYS D 440 4613 4841 4618 -60 1725 1173 C ATOM 3569 CB LYS D 440 66.617 5.319 -28.642 1.00 39.69 C ANISOU 3569 CB LYS D 440 5117 5293 4672 -5 1921 1245 C ATOM 3570 CG LYS D 440 67.882 4.548 -29.032 1.00 43.01 C ANISOU 3570 CG LYS D 440 5411 5768 5163 -42 2176 1205 C ATOM 3571 CD LYS D 440 68.388 4.877 -30.420 1.00 49.43 C ANISOU 3571 CD LYS D 440 6372 6631 5777 -42 2461 1354 C ATOM 3572 CE LYS D 440 69.683 4.104 -30.681 1.00 52.40 C ANISOU 3572 CE LYS D 440 6580 7061 6271 -70 2732 1294 C ATOM 3573 NZ LYS D 440 70.294 4.407 -32.006 1.00 56.62 N ANISOU 3573 NZ LYS D 440 7243 7651 6617 -78 3064 1439 N ATOM 3574 C LYS D 440 65.556 6.741 -26.849 1.00 36.89 C ANISOU 3574 C LYS D 440 4715 4726 4575 -33 1555 1259 C ATOM 3575 O LYS D 440 65.993 7.846 -26.543 1.00 37.86 O ANISOU 3575 O LYS D 440 4824 4692 4869 -113 1589 1372 O ATOM 3576 N ASP D 441 64.250 6.442 -26.917 1.00 35.37 N ANISOU 3576 N ASP D 441 4626 4620 4192 79 1370 1193 N ATOM 3577 CA ASP D 441 63.183 7.396 -26.655 1.00 34.86 C ANISOU 3577 CA ASP D 441 4660 4486 4100 145 1196 1252 C ATOM 3578 CB ASP D 441 62.914 8.221 -27.913 1.00 37.92 C ANISOU 3578 CB ASP D 441 5267 4866 4275 207 1267 1450 C ATOM 3579 CG ASP D 441 61.804 9.261 -27.730 1.00 40.30 C ANISOU 3579 CG ASP D 441 5676 5081 4554 307 1084 1529 C ATOM 3580 OD1 ASP D 441 61.425 9.618 -26.576 1.00 39.22 O ANISOU 3580 OD1 ASP D 441 5443 4850 4609 306 947 1449 O ATOM 3581 OD2 ASP D 441 61.301 9.721 -28.784 1.00 45.16 O

ANISOU 3581 OD2 ASP D 441 6486 5729 4944 401 1080 1674 O

ATOM 3582 C ASP D 441 61.900 6.717 -26.136 1.00 32.31 C ANISOU 3582 C ASP D 441 4311 4270 3697 235 971 1096 C ATOM 3583 O ASP D 441 61.199 6.013 -26.871 1.00 32.02 O ANISOU 3583 O ASP D 441 4348 4382 3436 310 920 1048 O ATOM 3584 N ALA D 442 61.576 6.945 -24.867 1.00 29.74 N ANISOU 3584 N ALA D 442 3881 3867 3552 220 839 1014 N ATOM 3585 CA ALA D 442 60.377 6.300 -24.287 1.00 27.57 C ANISOU 3585 CA ALA D 442 3558 3693 3225 289 658 871 C ATOM 3586 CB ALA D 442 60.695 5.663 -22.929 1.00 24.90 C ANISOU 3586 CB ALA D 442 3063 3329 3068 217 615 728 C ATOM 3587 C ALA D 442 59.104 7.154 -24.217 1.00 27.63 C ANISOU 3587 C ALA D 442 3630 3685 3182 404 506 909 C ATOM 3588 O ALA D 442 58.109 6.710 -23.648 1.00 27.53 O ANISOU 3588 O ALA D 442 3547 3753 3160 452 372 793 O ATOM 3589 N LYS D 443 59.122 8.344 -24.818 1.00 29.38 N ANISOU 3589 N LYS D 443 3983 3804 3377 452 535 1077 N ATOM 3590 CA LYS D 443 57.985 9.293 -24.817 1.00 30.50 C ANISOU 3590 CA LYS D 443 4196 3903 3492 591 395 1137 C ATOM 3591 CB LYS D 443 58.290 10.528 -25.671 1.00 33.67 C ANISOU 3591 CB LYS D 443 4779 4162 3853 630 465 1361 C ATOM 3592 CG LYS D 443 59.229 11.526 -25.065 1.00 36.65 C ANISOU 3592 CG LYS D 443 5167 4298 4461 529 567 1432 C ATOM 3593 CD LYS D 443 59.650 12.550 -26.133 1.00 45.40 C ANISOU 3593 CD LYS D 443 6473 5274 5503 538 680 1678 C ATOM 3594 CE LYS D 443 60.962 13.265 -25.747 1.00 47.82 C ANISOU 3594 CE LYS D 443 6766 5359 6046 363 843 1750 C ATOM 3595 NZ LYS D 443 61.530 14.054 -26.889 1.00 50.87 N ANISOU 3595 NZ LYS D 443 7337 5634 6356 332 1010 2003 N ATOM 3596 C LYS D 443 56.646 8.725 -25.307 1.00 30.23 C ANISOU 3596 C LYS D 443 4154 4060 3271 716 235 1077 C ATOM 3597 O LYS D 443 55.631 8.934 -24.669 1.00 29.75 O ANISOU 3597 O LYS D 443 4018 4015 3270 802 100 1008 O ATOM 3598 N VAL D 444 56.638 8.041 -26.453 1.00 30.26 N ANISOU 3598 N VAL D 444 4234 4210 3051 726 252 1098 N ATOM 3599 CA VAL D 444 55.407 7.466 -26.998 1.00 29.10 C ANISOU 3599 CA VAL D 444 4078 4254 2725 825 78 1029 C ATOM 3600 CB VAL D 444 55.585 6.963 -28.484 1.00 31.06 C ANISOU 3600 CB VAL D 444 4485 4636 2681 840 109 1084 C ATOM 3601 CG1 VAL D 444 54.288 6.421 -29.035 1.00 29.96 C ANISOU 3601 CG1 VAL D 444 4330 4691 2363 934 -109 999 C ATOM 3602 CG2 VAL D 444 56.115 8.078 -29.394 1.00 30.95 C ANISOU 3602 CG2 VAL D 444 4684 4520 2557 891 208 1324 C ATOM 3603 C VAL D 444 54.875 6.360 -26.079 1.00 27.62 C ANISOU 3603 C VAL D 444 3699 4166 2629 768 3 815 C ATOM 3604 O VAL D 444 53.680 6.285 -25.819 1.00 27.97 O ANISOU 3604 O VAL D 444 3650 4300 2679 844 -156 743 O ATOM 3605 N LEU D 445 55.788 5.542 -25.567 1.00 25.93 N ANISOU 3605 N LEU D 445 3422 3927 2503 636 126 725 N ATOM 3606 CA LEU D 445 55.501 4.447 -24.647 1.00 23.92 C ANISOU 3606 CA LEU D 445 3016 3731 2341 563 89 546 C ATOM 3607 CB LEU D 445 56.804 3.645 -24.334 1.00 21.91 C ANISOU 3607 CB LEU D 445 2738 3423 2166 439 243 496 C ATOM 3608 CG LEU D 445 56.751 2.511 -23.313 1.00 20.89 C ANISOU 3608 CG LEU D 445 2483 3313 2143 358 226 342 C ATOM 3609 CD1 LEU D 445 55.801 1.381 -23.778 1.00 20.54 C ANISOU 3609 CD1 LEU D 445 2418 3414 1973 353 132 220 C ATOM 3610 CD2 LEU D 445 58.144 1.953 -22.982 1.00 18.80 C ANISOU 3610 CD2 LEU D 445 2194 2968 1982 270 365 327 C ATOM 3611 C LEU D 445 54.862 4.932 -23.354 1.00 23.22 C ANISOU 3611 C LEU D 445 2811 3585 2427 587 19 499 C ATOM 3612 O LEU D 445 53.820 4.424 -22.965 1.00 24.32 O ANISOU 3612 O LEU D 445 2843 3827 2571 605 -83 395 O ATOM 3613 N PHE D 446 55.525 5.867 -22.678 1.00 22.66 N

ANISOU 3613 N PHE D 446 2760 3351 2500 576 85 565 N

ATOM 3614 CA PHE D 446 55.043 6.489 -21.438 1.00 21.33 C

ANISOU 3614 CA PHE D 446 2518 3103 2482 609 39 517 C

ATOM 3615 CB PHE D 446 56.138 7.400 -20.838 1.00 20.56 C

ANISOU 3615 CB PHE D 446 2473 2806 2534 555 124 577 C

ATOM 3616 CG PHE D 446 57.229 6.646 -20.076 1.00 19.42 C

ANISOU 3616 CG PHE D 446 2266 2630 2484 414 198 502 C

ATOM 3617 CD1 PHE D 446 57.332 5.253 -20.143 1.00 17.40 C

ANISOU 3617 CD1 PHE D 446 1945 2496 2168 352 213 418 C

ATOM 3618 CE1 PHE D 446 58.339 4.559 -19.453 1.00 20.22 C

ANISOU 3618 CE1 PHE D 446 2246 2816 2619 249 265 363 C

ATOM 3619 CZ PHE D 446 59.301 5.271 -18.691 1.00 19.91 C

ANISOU 3619 CZ PHE D 446 2198 2633 2733 192 291 386 C

ATOM 3620 CE2 PHE D 446 59.217 6.678 -18.646 1.00 19.69 C

ANISOU 3620 CE2 PHE D 446 2236 2480 2765 229 279 458 C

ATOM 3621 CD2 PHE D 446 58.186 7.346 -19.330 1.00 18.60 C

ANISOU 3621 CD2 PHE D 446 2170 2362 2535 345 240 519 C

ATOM 3622 C PHE D 446 53.719 7.274 -21.629 1.00 22.61 C

ANISOU 3622 C PHE D 446 2672 3302 2617 769 -82 546 C

ATOM 3623 O PHE D 446 52.788 7.129 -20.834 1.00 21.26 O

ANISOU 3623 O PHE D 446 2384 3189 2505 810 -143 444 O

ATOM 3624 N GLN D 447 53.634 8.092 -22.683 1.00 24.31 N

ANISOU 3624 N GLN D 447 3009 3485 2743 868 -111 691 N

ATOM 3625 CA GLN D 447 52.434 8.923 -22.930 1.00 26.58 C

ANISOU 3625 CA GLN D 447 3294 3792 3015 1051 -242 741 C

ATOM 3626 CB GLN D 447 52.727 10.052 -23.948 1.00 28.74 C

ANISOU 3626 CB GLN D 447 3759 3946 3215 1147 -240 948 C

ATOM 3627 CG GLN D 447 53.822 11.037 -23.521 1.00 28.97 C

ANISOU 3627 CG GLN D 447 3898 3721 3387 1085 -109 1039 C

ATOM 3628 CD GLN D 447 53.417 11.958 -22.367 1.00 31.94 C

ANISOU 3628 CD GLN D 447 4237 3939 3959 1160 -136 984 C

ATOM 3629 OE1 GLN D 447 52.467 11.685 -21.632 1.00 31.98 O

ANISOU 3629 OE1 GLN D 447 4103 4036 4012 1229 -210 849 O

ATOM 3630 NE2 GLN D 447 54.147 13.060 -22.209 1.00 32.72 N

ANISOU 3630 NE2 GLN D 447 4465 3791 4174 1139 -64 1083 N

ATOM 3631 C GLN D 447 51.172 8.138 -23.353 1.00 27.31 C

ANISOU 3631 C GLN D 447 3261 4112 3003 1115 -388 657 C

ATOM 3632 O GLN D 447 50.059 8.620 -23.205 1.00 28.77 O

ANISOU 3632 O GLN D 447 3359 4341 3230 1259 -502 646 O

ATOM 3633 N ASN D 448 51.353 6.919 -23.839 1.00 27.07 N

ANISOU 3633 N ASN D 448 3210 4218 2855 1005 -385 585 N

ATOM 3634 CA ASN D 448 50.262 6.088 -24.336 1.00 27.76 C

ANISOU 3634 CA ASN D 448 3189 4515 2844 1027 -531 492 C

ATOM 3635 CB ASN D 448 50.574 5.642 -25.776 1.00 28.82 C

ANISOU 3635 CB ASN D 448 3470 4742 2740 1014 -568 545 C

ATOM 3636 CG ASN D 448 50.346 6.749 -26.784 1.00 28.94 C

ANISOU 3636 CG ASN D 448 3635 4738 2623 1181 -656 726 C

ATOM 3637 OD1 ASN D 448 49.218 7.083 -27.082 1.00 31.76 O

ANISOU 3637 OD1 ASN D 448 3924 5192 2950 1320 -840 738 O

ATOM 3638 ND2 ASN D 448 51.414 7.321 -27.300 1.00 26.91 N

ANISOU 3638 ND2 ASN D 448 3577 4353 2295 1168 -523 876 N

ATOM 3639 C ASN D 448 49.972 4.866 -23.458 1.00 27.61 C

ANISOU 3639 C ASN D 448 3000 4579 2912 892 -508 312 C

ATOM 3640 O ASN D 448 49.042 4.091 -23.740 1.00 28.34 O

ANISOU 3640 O ASN D 448 2973 4834 2960 874 -623 214 O

ATOM 3641 N TRP D 449 50.740 4.720 -22.378 1.00 26.08 N

ANISOU 3641 N TRP D 449 2795 4267 2845 793 -369 274 N

ATOM 3642 CA TRP D 449 50.617 3.569 -21.487 1.00 26.10 C

ANISOU 3642 CA TRP D 449 2678 4318 2922 661 -326 133 C

ATOM 3643 CB TRP D 449 51.844 3.464 -20.552 1.00 22.77 C

ANISOU 3643 CB TRP D 449 2311 3748 2592 562 -183 131 C

ATOM 3644 CG TRP D 449 51.796 2.288 -19.626 1.00 22.86 C

ANISOU 3644 CG TRP D 449 2234 3788 2662 436 -140 15 C

ATOM 3645 CD1 TRP D 449 51.346 2.273 -18.330 1.00 19.13 C

ANISOU 3645 CD1 TRP D 449 1674 3305 2290 418 -109 -46 C ATOM 3646 NE1 TRP D 449 51.479 1.021 -17.799 1.00 18.46 N ANISOU 3646 NE1 TRP D 449 1555 3239 2218 288 -65 -120 N ATOM 3647 CE2 TRP D 449 52.025 0.180 -18.738 1.00 19.96 C ANISOU 3647 CE2 TRP D 449 1806 3444 2335 226 -70 -126 C ATOM 3648 CD2 TRP D 449 52.254 0.945 -19.905 1.00 22.60 C ANISOU 3648 CD2 TRP D 449 2219 3784 2585 316 -109 -47 C ATOM 3649 CE3 TRP D 449 52.810 0.315 -21.036 1.00 22.07 C ANISOU 3649 CE3 TRP D 449 2239 3740 2407 283 -102 -46 C ATOM 3650 CZ3 TRP D 449 53.121 -1.038 -20.960 1.00 20.32 C ANISOU 3650 CZ3 TRP D 449 2018 3518 2186 172 -64 -135 C ATOM 3651 CH2 TRP D 449 52.904 -1.767 -19.775 1.00 19.50 C ANISOU 3651 CH2 TRP D 449 1836 3385 2187.

86. 36 -201 C ATOM 3652 CZ2 TRP D 449 52.368 -1.173 -18.652 1.00 19.23 C ANISOU 3652 CZ2 TRP D 449 1723 3343 2240 108 -34 -191 C ATOM 3653 C TRP D 449 49.301 3.488 -20.696 1.00 26.80 C ANISOU 3653 C TRP D 449 2575 4500 3107 694 -385 42 C ATOM 3654 O TRP D 449 48.820 2.383 -20.387 1.00 28.17 O ANISOU 3654 O TRP D 449 2636 4768 3300 585 -389 -67 O ATOM 3655 N GLY D 450 48.724 4.626 -20.338 1.00 27.01 N ANISOU 3655 N GLY D 450 2562 4494 3209 839 -413 84 N ATOM 3656 CA GLY D 450 47.550 4.564 -19.465 1.00 26.85 C ANISOU 3656 CA GLY D 450 2343 4561 3298 873 -423 -10 C ATOM 3657 C GLY D 450 47.850 5.155 -18.104 1.00 26.36 C ANISOU 3657 C GLY D 450 2299 4371 3347 887 -298 -33 C ATOM 3658 O GLY D 450 48.936 4.913 -17.524 1.00 24.35 O ANISOU 3658 O GLY D 450 2156 4003 3095 777 -201 -34 O ATOM 3659 N ILE D 451 46.877 5.919 -17.597 1.00 26.86 N ANISOU 3659 N ILE D 451 2250 4457 3500 1030 -308 -60 N ATOM 3660 CA ILE D 451 47.001 6.664 -16.348 1.00 26.37 C ANISOU 3660 CA ILE D 451 2221 4274 3526 1082 -198 -98 C ATOM 3661 CB ILE D 451 46.969 8.237 -16.581 1.00 27.89 C ANISOU 3661 CB ILE D 451 2507 4318 3770 1289 -238 -20 C ATOM 3662 CG1 ILE D 451 47.657 9.008 -15.440 1.00 25.93 C ANISOU 3662 CG1 ILE D 451 2392 3875 3584 1293 -129 -57 C ATOM 3663 CD1 ILE D 451 49.176 9.125 -15.584 1.00 21.81 C ANISOU 3663 CD1 ILE D 451 2069 3187 3030 1167 -106 13 C ATOM 3664 CG2 ILE D 451 45.544 8.748 -16.801 1.00 27.64 C ANISOU 3664 CG2 ILE D 451 2298 4397 3809 1490 -315 -36 C ATOM 3665 C ILE D 451 45.874 6.181 -15.432 1.00 27.18 C ANISOU 3665 C ILE D 451 2116 4514 3696 1077 -132 -215 C ATOM 3666 O ILE D 451 44.791 5.803 -15.904 1.00 28.28 O ANISOU 3666 O ILE D 451 2060 4822 3862 1110 -204 -243 O ATOM 3667 N GLU D 452 46.130 6.140 -14.131 1.00 26.29 N ANISOU 3667 N GLU D 452 2042 4341 3606 102.

4. 283 N ATOM 3668 CA GLU D 452 45.061 5.692 -13.194 1.00 27.65 C ANISOU 3668 CA GLU D 452 2028 4647 3830 1011 109 -385 C ATOM 3669 CB GLU D 452 45.256 4.198 -12.798 1.00 26.19 C ANISOU 3669 CB GLU D 452 1818 4538 3597 781 176 -418 C ATOM 3670 CG GLU D 452 46.647 3.878 -12.149 1.00 24.41 C ANISOU 3670 CG GLU D 452 1815 4166 3293 656 231 -398 C ATOM 3671 CD GLU D 452 46.830 2.423 -11.743 1.00 24.76 C ANISOU 3671 CD GLU D 452 1852 4259 3296 455 291 -414 C ATOM 3672 OE1 GLU D 452 45.888 1.618 -11.901 1.00 31.91 O ANISOU 3672 OE1 GLU D 452 2587 5300 4236 384 309 -448 O ATOM 3673 OE2 GLU D 452 47.908 2.057 -11.253 1.00 23.36 O ANISOU 3673 OE2 GLU D 452 1834 3978 3064 366 315 -392 O ATOM 3674 C GLU D 452 45.042 6.574 -11.949 1.00 27.37 C ANISOU 3674 C GLU D 452 2061 4513 3825 1111 234 -449 C ATOM 3675 O GLU D 452 46.052 7.169 -11.604 1.00 26.55 O ANISOU 3675 O GLU D 452 2164 4236 3690 1111 242 -433 O ATOM 3676 N AHIS D 453 43.898 6.648 -11.278 0.50 29.37 N ANISOU 3676 N AHIS D 453 2137 4881 4142 1189 336 -532 N ATOM 3677 N BHIS D 453 43.885 6.656 -11.308 0.50 29.06 N ANISOU 3677 N BHIS D 453 2095 4843 4104 1192 332 -531 N ATOM 3678 CA AHIS D 453 43.836 7.247 -9.942 0.50 30.28 C ANISOU 3678 CA AHIS D 453 2326 4928 4250 1259 493 -622 C ATOM 3679 CA BHIS D 453 43.774 7.182 -9.955 0.50 29.69 C ANISOU 3679 CA BHIS D 453 2237 4868 4178 1254 495 -623 C ATOM 3680 CB AHIS D 453 42.418 7.692 -9.572 0.50 32.76 C ANISOU 3680 CB AHIS D 453 2411 5367 4670 1432 592 -703 C ATOM 3681 CB BHIS D 453 42.302 7.269 -9.541 0.50 31.70 C ANISOU 3681 CB BHIS D 453 2229 5287 4527 1371 609 -705 C ATOM 3682 CG AHIS D 453 42.349 8.492 -8.302 0.50 34.48 C ANISOU 3682 CG AHIS D 453 2734 5498 4869 1546 757 -810 C ATOM 3683 CG BHIS D 453 41.496 8.296 -10.288 0.50 33.06 C ANISOU 3683 CG BHIS D 453 2263 5469 4828 1622 512 -693 C ATOM 3684 ND1AHIS D 453 41.699 8.043 -7.170 0.50 37.07 N ANISOU 3684 ND1AHIS D 453 2974 5946 5164 1508 969 -904 N ATOM 3685 ND1BHIS D 453 40.830 8.013 -11.463 0.50 33.68 N ANISOU 3685 ND1BHIS D 453 2135 5683 4978 1653 357 -636 N ATOM 3686 CE1AHIS D 453 41.803 8.950 -6.214 0.50 37.81 C ANISOU 3686 CE1AHIS D 453 3219 5928 5219 1638 1082 -1002 C ATOM 3687 CE1BHIS D 453 40.176 9.092 -11.868 0.50 34.95 C ANISOU 3687 CE1BHIS D 453 2210 5823 5246 1913 285 -627 C ATOM 3688 NE2AHIS D 453 42.505 9.967 -6.682 0.50 37.40 N ANISOU 3688 NE2AHIS D 453 3344 5671 5195 1747 942 -976 N ATOM 3689 NE2BHIS D 453 40.397 10.065 -11.001 0.50 33.44 N ANISOU 3689 NE2BHIS D 453 2168 5472 5067 2049 403 -686 N ATOM 3690 CD2AHIS D 453 42.863 9.704 -7.982 0.50 34.66 C ANISOU 3690 CD2AHIS D 453 2960 5318 4892 1690 748 -845 C ATOM 3691 CD2BHIS D 453 41.208 9.589 -9.998 0.50 33.77 C ANISOU 3691 CD2BHIS D 453 2392 5449 4990 1865 542 -736 C ATOM 3692 C AHIS D 453 44.368 6.267 -8.900 0.50 29.31 C ANISOU 3692 C AHIS D 453 2300 4818 4018 1058 615 -655 C ATOM 3693 C BHIS D 453 44.521 6.231 -8.998 0.50 28.61 C ANISOU 3693 C BHIS D 453 2231 4715 3923 1044 596 -643 C ATOM 3694 O AHIS D 453 44.077 5.067 -8.933 0.50 29.41 O ANISOU 3694 O AHIS D 453 2203 4957 4013 899 649 -643 O ATOM 3695 O BHIS D 453 44.536 5.005 -9.196 0.50 27.91 O ANISOU 3695 O BHIS D 453 2079 4722 3805 868 596 -612 O ATOM 3696 N ILE D 454 45.164 6.783 -7.978 1.00 28.76 N ANISOU 3696 N ILE D 454 2449 4605 3874 1063 667 -695 N ATOM 3697 CA ILE D 454 45.777 5.937 -6.964 1.00 28.13 C ANISOU 3697 CA ILE D 454 2498 4524 3669 893 751 -712 C ATOM 3698 CB ILE D 454 47.332 5.999 -7.018 1.00 26.26 C ANISOU 3698 CB ILE D 454 2490 4116 3371 803 634 -662 C ATOM 3699 CG1 ILE D 454 47.890 7.250 -6.344 1.00 24.68 C ANISOU 3699 CG1 ILE D 454 2478 3746 3152 906 625 -733 C ATOM 3700 CD1 ILE D 454 49.392 7.303 -6.398 1.00 25.66 C ANISOU 3700 CD1 ILE D 454 2783 3717 3249 801 503 -689 C ATOM 3701 CG2 ILE D 454 47.826 5.855 -8.457 1.00 23.15 C ANISOU 3701 CG2 ILE D 454 2062 3692 3042 772 483 -559 C ATOM 3702 C ILE D 454 45.222 6.230 -5.576 1.00 30.71 C ANISOU 3702 C ILE D 454 2860 4884 3925 953 938 -822 C ATOM 3703 O ILE D 454 44.661 7.306 -5.345 1.00 32.07 O ANISOU 3703 O ILE D 454 3011 5025 4150 1141 991 -901 O ATOM 3704 N ASP D 455 45.333 5.234 -4.691 1.00 32.26 N ANISOU 3704 N ASP D 455 3111 5146 4000 800 1047 -821 N ATOM 3705 CA ASP D 455 45.106 5.380 -3.250 1.00 34.47 C ANISOU 3705 CA ASP D 455 3507 5446 4142 822 1227 -911 C ATOM 3706 CB ASP D 455 44.729 4.030 -2.628 1.00 35.56 C ANISOU 3706 CB ASP D 455 3602 5719 4189 648 1374 -865 C ATOM 3707 CG ASP D 455 43.446 3.430 -3.228 1.00 39.76 C ANISOU 3707 CG ASP D 455 3816 6426 4866 618 1465 -844 C ATOM 3708 OD1 ASP D 455 42.493 4.181 -3.532 1.00 42.46 O ANISOU 3708 OD1 ASP D 455 3961 6837 5333 779 1511 -908 O ATOM 3709 OD2 ASP D 455 43.394 2.189 -3.401 1.00 44.22 O ANISOU 3709 OD2 ASP D 455 4320 7051 5432 431 1479 -765 O ATOM 3710 C ASP D 455 46.372 5.899 -2.568 1.00 34.03 C ANISOU 3710 C ASP D 455 3751 5221 3959 814 1139 -945 C ATOM 3711 O ASP D 455 47.494 5.599 -2.992 1.00 31.59 O ANISOU 3711 O ASP D 455 3543 4815 3646 712 975 -870 O ATOM 3712 N ASN D 456 46.191 6.679 -1.505 1.00 36.31 N ANISOU 3712 N ASN D 456 4174 5475 4146 921 1248 -1069 N ATOM 3713 CA ASN D 456 47.306 7.068 -0.637 1.00 36.72 C ANISOU 3713 CA ASN D 456 4519 5389 4046 891 1168 -1127 C ATOM 3714 CB ASN D 456 46.871 8.172 0.341 1.00 39.40 C ANISOU 3714 CB ASN D 456 4986 5683 4301 1056 1292 -1302 C ATOM 3715 CG ASN D 456 46.475 9.447 -0.357 1.00 40.47 C ANISOU 3715 CG ASN D 456 5043 5708 4625 1250 1255 -1367 C ATOM 3716 OD1 ASN D 456 47.200 9.934 -1.227 1.00 42.70 O ANISOU 3716 OD1 ASN D 456 5348 5842 5034 1246 1067 -1312 O ATOM 3717 ND2 ASN D 456 45.322 9.995 0.010 1.00 40.50 N ANISOU 3717 ND2 ASN D 456 4954 5779 4655 1427 1445 -1475 N ATOM 3718 C ASN D 456 47.813 5.870 0.159 1.00 36.38 C ANISOU 3718 C ASN D 456 4600 5409 3814 717 1191 -1062 C ATOM 3719 O ASN D 456 47.117 5.374 1.047 1.00 39.46 O ANISOU 3719 O ASN D 456 5005 5924 4065 698 1387 -1084 O ATOM 3720 N VAL D 457 49.004 5.398 -0.170 1.00 34.18 N ANISOU 3720 N VAL D 457 4405 5046 3536 597 1001 -974 N ATOM 3721 CA VAL D 457 49.676 4.338 0.582 1.00 33.74 C ANISOU 3721 CA VAL D 457 4497 5014 3310 455 975 -903 C ATOM 3722 CB VAL D 457 49.883 3.059 -0.286 1.00 32.28 C ANISOU 3722 CB VAL D 457 4179 4866 3220 319 921 -748 C ATOM 3723 CG1 VAL D 457 50.617 1.967 0.500 1.00 32.61 C ANISOU 3723 CG1 VAL D 457 4387 4904 3098 195 883 -661 C ATOM 3724 CG2 VAL D 457 48.541 2.522 -0.807 1.00 33.51 C ANISOU 3724 CG2 VAL D 457 4097 5162 3471 308 1091 -717 C ATOM 3725 C VAL D 457 51.031 4.904 1.032 1.00 32.68 C ANISOU 3725 C VAL D 457 4580 4731 3105 444 773 -949 C ATOM 3726 O VAL D 457 51.822 5.334 0.185 1.00 30.77 O ANISOU 3726 O VAL D 457 4297 4375 3018 437 604 -926 O ATOM 3727 N MSE D 458 51.279 4.935 2.348 1.00 33.57 N ANISOU 3727 N MSE D 458 4921 4852 2984 440 792 -1018 N ATOM 3728 CA MSE D 458 52.542 5.460 2.892 1.00 33.03 C ANISOU 3728 CA MSE D 458 5058 4656 2837 420 576 -1082 C ATOM 3729 CB MSE D 458 52.509 5.541 4.421 1.00 35.52 C ANISOU 3729 CB MSE D 458 5638 5013 2845 439 627 -1182 C ATOM 3730 CG MSE D 458 53.711 6.288 5.016 1.00 34.66 C ANISOU 3730 CG MSE D 458 5739 4772 2659 428 383 -1294 C ATOM 3731 SE MSE D 458 53.851 6.197 6.940 0.90 39.03 SE ANISOU 3731 SE MSE D 458 6670 5394 2765 437 388 -1406 SE ATOM 3732 CE MSE D 458 55.169 7.548 7.238 1.00 40.64 C ANISOU 3732 CE MSE D 458 7044 5395 3003 43.

59. 1605 C ATOM 3733 C MSE D 458 53.711 4.597 2.449 1.00 31.60 C ANISOU 3733 C MSE D 458 4852 4434 2721 297 378 -943 C ATOM 3734 O MSE D 458 53.591 3.367 2.390 1.00 31.80 O ANISOU 3734 O MSE D 458 4832 4541 2711 221 428 -811 O ATOM 3735 N GLY D 459 54.833 5.231 2.119 1.00 30.97 N ANISOU 3735 N GLY D 459 4791 4220 2755 277 165 -973 N ATOM 3736 CA GLY D 459 56.032 4.514 1.643 1.00 29.96 C ANISOU 3736 CA GLY D 459 4609 4050 2725 178 -21 -853 C ATOM 3737 C GLY D 459 56.149 4.354 0.118 1.00 28.53 C ANISOU 3737 C GLY D 459 4203 3839 2800 157 -754 C ATOM 3738 O GLY D 459 57.067 3.695 -0.379 1.00 27.21 O ANISOU 3738 O GLY D 459 3968 3645 272.

88. 141 -656 O ATOM 3739 N MSE D 460 55.240 4.983 -0.620 1.00 28.31 N ANISOU 3739 N MSE D 460 4064 3815 2879 23.

96. 784 N ATOM 3740 CA MSE D 460 55.042 4.734 -2.044 1.00 28.35 C ANISOU 3740 CA MSE D 460 3874 3830 3069 225 124 -688 C ATOM 3741 CB MSE D 460 54.078 3.573 -2.174 1.00 27.77 C ANISOU 3741 CB MSE D 460 3709 3898 2944 200 267 -617 C ATOM 3742 CG MSE D 460 54.112 2.810 -3.436 1.00 30.07 C ANISOU 3742 CG MSE D 460 3842 4216 3368 152 259 -511 C ATOM 3743 SE MSE D 460 52.689 1.457 -3.282 0.90 33.52 SE ANISOU 3743 SE MSE D 460 4185 4819 3732 100 451 -464 SE ATOM 3744 CE MSE D 460 53.605 0.285 -1.992 1.00 34.15 C ANISOU 3744 CE MSE D 460 4467 4874 3636 -1 401 -395 C ATOM 3745 C MSE D 460 54.378 5.961 -2.667 1.00 26.69 C ANISOU 3745 C MSE D 460 3605 3566 2972 333 177 -750 C ATOM 3746 O MSE D 460 53.553 6.615 -2.027 1.00 27.88 O ANISOU 3746 O MSE D 460 3813 3730 3051 427 275 -855 O ATOM 3747 N VAL D 461 54.750 6.277 -3.901 1.00 24.21 N ANISOU 3747 N VAL D 461 3187 3185 2826 331 120 -682 N ATOM 3748 CA VAL D 461 54.111 7.350 -4.657 1.00 23.60 C ANISOU 3748 CA VAL D 461 3055 3051 2861 443 159 -701 C ATOM 3749 CB VAL D 461 54.973 8.683 -4.716 1.00 24.29 C ANISOU 3749 CB VAL D 461 3246 2931 3053 45.

54. 748 C ATOM 3750 CG1 VAL D 461 54.919 9.441 -3.418 1.00 26.49 C ANISOU 3750 CG1 VAL D 461 3693 3135 3236 49.

49. 907 C ATOM 3751 CG2 VAL D 461 56.409 8.417 -5.145 1.00 21.55 C ANISOU 3751 CG2 VAL D 461 2887 2510 2790 322 -73 -669 C ATOM 3752 C VAL D 461 53.857 6.895 -6.082 1.00 21.54 C ANISOU 3752 C VAL D 461 2635 2848 2701 440 169 -582 C ATOM 3753 O VAL D 461 54.504 5.950 -6.569 1.00 20.30 O ANISOU 3753 O VAL D 461 2431 2727 2556 340 127 -497 O ATOM 3754 N GLY D 462 52.960 7.610 -6.757 1.00 21.64 N ANISOU 3754 N GLY D 462 2577 2862 2782 561 213 -581 N ATOM 3755 CA GLY D 462 52.766 7.470 -8.213 1.00 20.05 C ANISOU 3755 CA GLY D 462 2259 2696 2664 580 191 -472 C ATOM 3756 C GLY D 462 53.780 8.244 -9.042 1.00 19.20 C ANISOU 3756 C GLY D 462 2210 2429 2656 563 109 -399 C ATOM 3757 O GLY D 462 54.540 9.061 -8.544 1.00 19.52 O ANISOU 3757 O GLY D 462 2363 2313 2739 54.

65. 439 O ATOM 3758 N VAL D 463 53.780 8.004 -10.337 1.00 18.47 N ANISOU 3758 N VAL D 463 2045 2375 2599 56.

93. 292 N ATOM 3759 CA VAL D 463 54.761 8.620 -11.196 1.00 18.33 C ANISOU 3759 CA VAL D 463 2080 2223 2662 53.

49. 199 C ATOM 3760 CB VAL D 463 56.088 7.738 -11.343 1.00 18.13 C ANISOU 3760 CB VAL D 463 2045 2200 2645 37.

27. 152 C ATOM 3761 CG1 VAL D 463 55.844 6.407 -12.051 1.00 15.46 C ANISOU 3761 CG1 VAL D 463 1612 2021 2239 33.

52. 108 C ATOM 3762 CG2 VAL D 463 57.144 8.490 -12.103 1.00 18.20 C ANISOU 3762 CG2 VAL D 463 2096 2063 2755 32.

12. 63 C ATOM 3763 C VAL D 463 54.076 8.889 -12.517 1.00 18.79 C ANISOU 3763 C VAL D 463 2091 2324 2726 63.

47. 103 C ATOM 3764 O VAL D 463 53.343 8.039 -13.061 1.00 18.59 O ANISOU 3764 O VAL D 463 1963 2463 2636 64.

53. 87 O ATOM 3765 N LEU D 464 54.245 10.107 -12.999 1.00 19.85 N ANISOU 3765 N LEU D 464 2307 2300 2934 70.

29. 42 N ATOM 3766 CA LEU D 464 53.639 10.532 -14.258 1.00 20.22 C ANISOU 3766 CA LEU D 464 2344 2365 2972 816 9 71 C ATOM 3767 CB LEU D 464 53.298 12.015 -14.196 1.00 21.24 C ANISOU 3767 CB LEU D 464 2572 2308 3190 958 -6 86 C ATOM 3768 CG LEU D 464 52.392 12.555 -13.082 1.00 21.78 C ANISOU 3768 CG LEU D 464 2634 2349 3293 108.

11. 55 C ATOM 3769 CD1 LEU D 464 52.192 14.033 -13.307 1.00 21.48 C ANISOU 3769 CD1 LEU D 464 2714 2089 3357 1234 -8 -13 C ATOM 3770 CD2 LEU D 464 51.033 11.835 -13.039 1.00 19.48 C ANISOU 3770 CD2 LEU D 464 2173 2290 2938 118.

22. 109 C ATOM 3771 C LEU D 464 54.600 10.221 -15.434 1.00 20.13 C ANISOU 3771 C LEU D 464 2363 2346 2938 720 16 205 C ATOM 3772 O LEU D 464 55.774 9.957 -15.215 1.00 19.34 O ANISOU 3772 O LEU D 464 2286 2186 2877 580 42 209 O ATOM 3773 N PRO D 465 54.096 10.203 -16.684 1.00 21.70 N ANISOU 3773 N PRO D 465 2556 2622 3065 799 -8 311 N ATOM 3774 CA PRO D 465 54.985 9.992 -17.845 1.00 22.57 C ANISOU 3774 CA PRO D 465 2723 2726 3126 722 25 440 C ATOM 3775 CB PRO D 465 54.069 10.254 -19.037 1.00 23.86 C ANISOU 3775 CB PRO D 465 2910 2970 3187 865 -34 540 C ATOM 3776 CG PRO D 465 52.699 9.890 -18.550 1.00 23.05 C ANISOU 3776 CG PRO D 465 2677 3013 3067 968 -105 429 C ATOM 3777 CD PRO D 465 52.675 10.307 -17.092 1.00 22.87 C ANISOU 3777 CD PRO D 465 2637 2889 3164 965 -71 311 C ATOM 3778 C PRO D 465 56.248 10.874 -17.928 1.00 25.04 C ANISOU 3778 C PRO D 465 3145 2825 3544 637 84 529 C ATOM 3779 O PRO D 465 57.278 10.395 -18.414 1.00 25.30 O ANISOU 3779 O PRO D 465 3176 2867 3570 517 149 583 O ATOM 3780 N ASP D 466 56.170 12.133 -17.480 1.00 26.78 N ANISOU 3780 N ASP D 466 3452 2849 3874 696 69 538 N ATOM 3781 CA ASP D 466 57.344 13.009 -17.382 1.00 28.69 C ANISOU 3781 CA ASP D 466 3786 2862 4253 586 117 599 C ATOM 3782 CB ASP D 466 56.953 14.498 -17.491 1.00 31.09 C ANISOU 3782 CB ASP D 466 4230 2938 4643 702 98 670 C ATOM 3783 CG ASP D 466 56.078 14.998 -16.330 1.00 32.24 C ANISOU 3783 CG ASP D 466 4380 3024 4845 822 37 512 C ATOM 3784 OD1 ASP D 466 55.823 14.292 -15.330 1.00 30.53 O ANISOU 3784 OD1 ASP D 466 4070 2932 4599 800 19 349 O ATOM 3785 OD2 ASP D 466 55.642 16.161 -16.413 1.00 38.19 O ANISOU 3785 OD2 ASP D 466 5248 3591 5673 948 19 556 O ATOM 3786 C ASP D 466 58.190 12.757 -16.130 1.00 28.75 C ANISOU 3786 C ASP D 466 3742 2819 4363 442 111 460 C ATOM 3787 O ASP D 466 59.120 13.523 -15.851 1.00 29.86 O ANISOU 3787 O ASP D 466 3937 2764 4644 338 125 475 O ATOM 3788 N MSE D 467 57.871 11.674 -15.404 1.00 27.82 N ANISOU 3788 N MSE D 467 3523 2874 4173 430 82 334 N ATOM 3789 CA MSE D 467 58.653 11.191 -14.238 1.00 27.18 C ANISOU 3789 CA MSE D 467 3395 2788 4144 304 55 213 C ATOM 3790 CB MSE D 467 60.143 11.016 -14.581 1.00 27.16 C ANISOU 3790 CB MSE D 467 3352 2728 4238 142 90 280 C ATOM 3791 CG MSE D 467 60.473 9.801 -15.486 1.00 26.75 C ANISOU 3791 CG MSE D 467 3210 2847 4106 108 154 349 C ATOM 3792 SE MSE D 467 59.696 8.138 -14.902 0.90 30.05 SE ANISOU 3792 SE MSE D 467 3540 3499 4378 144 116 232 SE ATOM 3793 CE MSE D 467 60.578 8.025 -13.137 1.00 28.88 C ANISOU 3793 CE MSE D 467 3369 3279 4325 39 26 100 C ATOM 3794 C MSE D 467 58.470 12.021 -12.971 1.00 27.94 C ANISOU 3794 C MSE D 467 3565 2749 4304 327 -1 81 C ATOM 3795 O MSE D 467 59.154 11.804 -11.978 1.00 28.10 O ANISOU 3795 O MSE D 467 3577 2745 4357 227 -48 -18 O ATOM 3796 N THR D 468 57.548 12.977 -13.020 1.00 28.97 N ANISOU 3796 N THR D 468 3776 2788 4443 470 -3 77 N ATOM 3797 CA THR D 468 57.137 13.732 -11.838 1.00 30.36 C ANISOU 3797 CA THR D 468 4035 2848 4652 533 -37 -73 C ATOM 3798 CB THR D 468 56.270 14.949 -12.237 1.00 32.44 C ANISOU 3798 CB THR D 468 4395 2963 4969 710 -26 -37 C ATOM 3799 OG1 THR D 468 57.079 15.883 -12.965 1.00 35.37 O ANISOU 3799 OG1 THR D 468 4863 3109 5468 645 -20 91 O ATOM 3800 CG2 THR D 468 55.697 15.678 -11.014 1.00 36.00 C ANISOU 3800 CG2 THR D 468 4932 3304 5441 809 -40 -217 C ATOM 3801 C THR D 468 56.377 12.807 -10.868 1.00 28.96 C ANISOU 3801 C THR D 468 3791 2867 4345 575 -208 C ATOM 3802 O THR D 468 55.453 12.082 -11.295 1.00 27.88 O ANISOU 3802 O THR D 468 3558 2917 4118 657 -2 -178 O ATOM 3803 N PRO D 469 56.760 12.819 -9.568 1.00 28.78 N ANISOU 3803 N PRO D 469 3824 2804 4307 512 -72 -354 N ATOM 3804 CA PRO D 469 56.011 12.034 -8.581 1.00 28.00 C ANISOU 3804 CA PRO D 469 3694 2876 4068 554 -47 -469 C ATOM 3805 CB PRO D 469 56.847 12.161 -7.306 1.00 28.47 C ANISOU 3805 CB PRO D 469 3854 2854 4107 451 -118 -600 C ATOM 3806 CG PRO D 469 57.615 13.422 -7.471 1.00 30.60 C ANISOU 3806 CG PRO D 469 4223 2871 4532 407 -176 -605 C ATOM 3807 CD PRO D 469 57.864 13.578 -8.946 1.00 30.30 C ANISOU 3807 CD PRO D 469 4118 2793 4602 395 -144 -421 C ATOM 3808 C PRO D 469 54.628 12.624 -8.344 1.00 28.95 C ANISOU 3808 C PRO D 469 3830 3009 4161 74.

18. 541 C ATOM 3809 O PRO D 469 54.422 13.821 -8.471 1.00 31.03 O ANISOU 3809 O PRO D 469 4181 3092 4515 84.

15. 558 O ATOM 3810 N SER D 470 53.680 11.773 -8.007 1.00 28.12 N ANISOU 3810 N SER D 470 3630 3107 3946 79.

84. 579 N ATOM 3811 CA SER D 470 52.325 12.211 -7.789 1.00 28.32 C ANISOU 3811 CA SER D 470 3619 3181 3962 984 162 -647 C ATOM 3812 CB SER D 470 51.519 12.098 -9.070 1.00 27.33 C ANISOU 3812 CB SER D 470 3351 3150 3883 1084 164 -524 C ATOM 3813 OG SER D 470 50.209 12.579 -8.834 1.00 30.16 O ANISOU 3813 OG SER D 470 3644 3556 4261 1280 230 -595 O ATOM 3814 C SER D 470 51.727 11.317 -6.739 1.00 28.11 C ANISOU 3814 C SER D 470 3546 3336 3798 967 247 -746 C ATOM 3815 O SER D 470 51.955 10.097 -6.738 1.00 26.67 O ANISOU 3815 O SER D 470 3294 3298 3541 842 249 -697 O ATOM 3816 N THR D 471 50.970 11.922 -5.847 1.00 29.88 N ANISOU 3816 N THR D 471 3821 3542 3989 1095 330 -882 N ATOM 3817 CA THR D 471 50.235 11.190 -4.825 1.00 31.76 C ANISOU 3817 CA THR D 471 4022 3958 4090 1099 454 -973 C ATOM 3818 CB THR D 471 50.322 11.895 -3.438 1.00 34.06 C ANISOU 3818 CB THR D 471 4508 4151 4283 1147 504 -1155 C ATOM 3819 OG1 THR D 471 49.928 13.268 -3.563 1.00 36.80 O ANISOU 3819 OG1 THR D 471 4916 4323 4743 1327 515 -1233 O ATOM 3820 CG2 THR D 471 51.762 11.842 -2.895 1.00 34.68 C ANISOU 3820 CG2 THR D 471 4765 4112 4299 980 369 -1177 C ATOM 3821 C THR D 471 48.769 10.996 -5.221 1.00 32.22 C ANISOU 3821 C THR D 471 3872 4182 4189 1237 567 -962 C ATOM 3822 O THR D 471 47.976 10.500 -4.422 1.00 33.96 O ANISOU 3822 O THR D 471 4032 4552 4321 1256 707 -1035 O ATOM 3823 N GLU D 472 48.430 11.356 -6.463 1.00 31.70 N ANISOU 3823 N GLU D 472 3692 4098 4254 1325 502 -862 N ATOM 3824 CA GLU D 472 47.035 11.363 -6.926 1.00 32.30 C ANISOU 3824 CA GLU D 472 3552 4318 4400 1483 566 -856 C ATOM 3825 CB GLU D 472 46.564 12.792 -7.215 1.00 34.20 C ANISOU 3825 CB GLU D 472 3825 4402 4768 1721 548 -885 C ATOM 3826 CG GLU D 472 46.472 13.710 -6.001 1.00 39.23 C ANISOU 3826 CG GLU D 472 4619 4902 5385 1834 650 -1059 C ATOM 3827 CD GLU D 472 47.149 15.074 -6.249 1.00 44.76 C ANISOU 3827 CD GLU D 472 5528 5294 6185 1917 554 -1063 C ATOM 3828 OE1 GLU D 472 46.462 16.121 -6.201 1.00 47.87 O ANISOU 3828 OE1 GLU D 472 5937 5570 6681 2147 593 -1130 O ATOM 3829 OE2 GLU D 472 48.384 15.090 -6.500 1.00 45.99 O ANISOU 3829 OE2 GLU D 472 5826 5316 6333 1749 444 -998 O ATOM 3830 C GLU D 472 46.839 10.501 -8.164 1.00 29.96 C ANISOU 3830 C GLU D 472 3083 4165 4136 1413 484 -717 C ATOM 3831 O GLU D 472 45.842 9.804 -8.275 1.00 29.57 O ANISOU 3831 O GLU D 472 2827 4313 4094 1424 541 -722 O ATOM 3832 N MSE D 473 47.796 10.559 -9.100 1.00 28.19 N ANISOU 3832 N MSE D 473 2943 3839 3930 1336 355 -601 N ATOM 3833 CA MSE D 473 47.703 9.800 -10.341 1.00 26.31 C ANISOU 3833 CA MSE D 473 2581 3719 3695 1276 272 -481 C ATOM 3834 CB MSE D 473 47.452 10.726 -11.552 1.00 27.81 C ANISOU 3834 CB MSE D 473 2766 3834 3967 1434 167 -380 C ATOM 3835 CG MSE D 473 46.264 11.657 -11.443 1.00 26.21 C ANISOU 3835 CG MSE D 473 2472 3630 3858 1680 188 -429 C ATOM 3836 SE MSE D 473 44.516 10.785 -11.482 0.90 29.78 SE ANISOU 3836 SE MSE D 473 2569 4404 4342 1752 231 -487 SE ATOM 3837 CE MSE D 473 44.552 10.081 -13.324 1.00 24.55 C ANISOU 3837 CE MSE D 473 1821 3865 3642 168.

30. 325 C ATOM 3838 C MSE D 473 48.978 9.045 -10.570 1.00 24.24 C ANISOU 3838 C MSE D 473 2418 3421 3371 1074 225 -417 C ATOM 3839 O MSE D 473 50.039 9.420 -10.051 1.00 23.22 O ANISOU 3839 O MSE D 473 2450 3138 3233 1006 216 -432 O ATOM 3840 N SER D 474 48.890 8.004 -11.387 1.00 22.74 N ANISOU 3840 N SER D 474 2125 3368 3148 983 187 -352 N ATOM 3841 CA SER D 474 50.092 7.287 -11.803 1.00 20.80 C ANISOU 3841 CA SER D 474 1959 3086 2859 820 146 -285 C ATOM 3842 CB SER D 474 50.489 6.264 -10.751 1.00 19.28 C ANISOU 3842 CB SER D 474 1787 2935 2604 675 208 -343 C ATOM 3843 OG SER D 474 51.820 5.854 -10.984 1.00 16.43 O ANISOU 3843 OG SER D 474 1518 2493 2230 553 164 -287 O ATOM 3844 C SER D 474 49.928 6.603 -13.137 1.00 20.73 C ANISOU 3844 C SER D 474 1868 3182 2825 78.

81. 205 C ATOM 3845 O SER D 474 48.821 6.295 -13.530 1.00 21.95 O ANISOU 3845 O SER D 474 1877 3482 2983 84.

62. 221 O ATOM 3846 N MSE D 475 51.037 6.376 -13.838 1.00 20.98 N ANISOU 3846 N MSE D 475 1989 3147 2833 70.

46. 127 N ATOM 3847 CA MSE D 475 51.056 5.443 -14.964 1.00 21.48 C ANISOU 3847 CA MSE D 475 2006 3317 2838 63.

5. 80 C ATOM 3848 CB MSE D 475 52.472 5.270 -15.530 1.00 19.83 C ANISOU 3848 CB MSE D 475 1910 3013 2612 54.

10. 6 C ATOM 3849 CG MSE D 475 52.894 6.455 -16.381 1.00 20.37 C ANISOU 3849 CG MSE D 475 2076 2969 2696 631 -15 102 C ATOM 3850 SE MSE D 475 54.525 6.239 -17.395 0.90 22.90 SE ANISOU 3850 SE MSE D 475 2500 3209 2992 523 29 211 SE ATOM 3851 CE MSE D 475 55.763 6.073 -15.923 1.00 15.43 C ANISOU 3851 CE MSE D 475 1566 2140 2155 395 75 144 C ATOM 3852 C MSE D 475 50.505 4.108 -14.458 1.00 21.28 C ANISOU 3852 C MSE D 475 1873 3425 2786 53.

40. 159 C ATOM 3853 O MSE D 475 50.898 3.647 -13.399 1.00 20.98 O ANISOU 3853 O MSE D 475 1867 3355 2749 451 102 -203 O ATOM 3854 N ARG D 476 49.570 3.531 -15.206 1.00 22.47 N ANISOU 3854 N ARG D 476 1904 3721 2914 539 -9 -173 N ATOM 3855 CA ARG D 476 48.834 2.320 -14.818 1.00 22.84 C ANISOU 3855 CA ARG D 476 1826 3891 2961 43.

23. 248 C ATOM 3856 CB ARG D 476 47.933 1.869 -15.985 1.00 23.67 C ANISOU 3856 CB ARG D 476 1807 4140 3046 439 -79 -261 C ATOM 3857 CG ARG D 476 47.287 0.475 -15.783 1.00 27.51 C ANISOU 3857 CG ARG D 476 2172 4732 3549 284 -56 -339 C ATOM 3858 CD ARG D 476 46.787 -0.218 -17.071 1.00 27.82 C ANISOU 3858 CD ARG D 476 2140 4882 3546 238 -183 -369 C ATOM 3859 NE ARG D 476 47.530 0.020 -18.335 1.00 32.26 N ANISOU 3859 NE ARG D 476 2845 5411 4002 288 -273 -313 N ATOM 3860 CZ ARG D 476 48.407 -0.822 -18.879 1.00 31.84 C ANISOU 3860 CZ ARG D 476 2916 5306 3876 190 -263 -319 C ATOM 3861 NH1 ARG D 476 48.759 -1.946 -18.240 1.00 32.87 N ANISOU 3861 NH1 ARG D 476 3064 5384 404.

43. 180 -370 N ATOM 3862 NH2 ARG D 476 48.962 -0.521 -20.040 1.00 28.92 N ANISOU 3862 NH2 ARG D 476 2666 4927 3395 249 -323 -268 N ATOM 3863 C ARG D 476 49.715 1.168 -14.282 1.00 20.44 C ANISOU 3863 C ARG D 476 1601 3533 2632 27.

84. 261 C ATOM 3864 O ARG D 476 50.603 0.659 -14.985 1.00 19.53 O ANISOU 3864 O ARG D 476 1567 3372 2481 21.

57. 227 O ATOM 3865 N GLY D 477 49.476 0.777 -13.028 1.00 20.13 N ANISOU 3865 N GLY D 477 1544 3497 2606 212 174 -303 N ATOM 3866 CA GLY D 477 50.241 -0.307 -12.377 1.00 19.10 C ANISOU 3866 CA GLY D 477 1500 3308 2451 77 223 -300 C ATOM 3867 C GLY D 477 51.654 0.032 -11.943 1.00 18.37 C ANISOU 3867 C GLY D 477 1558 3076 2345 81 215 -259 C ATOM 3868 O GLY D 477 52.351 -0.837 -11.447 1.00 18.98 O ANISOU 3868 O GLY D 477 1702 3100 2407 -7 233 -246 O ATOM 3869 N ILE D 478 52.094 1.285 -12.110 1.00 18.42 N ANISOU 3869 N ILE D 478 1614 3013 2371 179 180 -235 N ATOM 3870 CA ILE D 478 53.467 1.698 -11.747 1.00 17.40 C ANISOU 3870 CA ILE D 478 1602 2752 2259 167 158 -203 C ATOM 3871 CB ILE D 478 54.167 2.509 -12.862 1.00 17.64 C ANISOU 3871 CB ILE D 478 1662 2712 2328 215 115 -140 C ATOM 3872 CG1 ILE D 478 53.884 1.926 -14.282 1.00 18.18 C ANISOU 3872 CG1 ILE D 478 1682 2862 2363 21.

98. 108 C ATOM 3873 CD1 ILE D 478 54.456 0.525 -14.545 1.00 17.82 C ANISOU 3873 CD1 ILE D 478 1642 2831 2299 109 115 -115 C ATOM 3874 CG2 ILE D 478 55.699 2.688 -12.556 1.00 16.84 C ANISOU 3874 CG2 ILE D 478 1638 2484 2276 16.

98. 107 C ATOM 3875 C ILE D 478 53.516 2.522 -10.450 1.00 18.27 C ANISOU 3875 C ILE D 478 1780 2801 2362 205 175 -248 C ATOM 3876 O ILE D 478 52.759 3.501 -10.278 1.00 19.57 O ANISOU 3876 O ILE D 478 1928 2971 2538 304 192 -284 O ATOM 3877 N ARG D 479 54.407 2.131 -9.538 1.00 17.66 N ANISOU 3877 N ARG D 479 1785 2662 2261 138 160 -252 N ATOM 3878 CA ARG D 479 54.620 2.867 -8.297 1.00 18.17 C ANISOU 3878 CA ARG D 479 1947 2665 2291 163 152 -308 C ATOM 3879 CB ARG D 479 53.947 2.147 -7.108 1.00 19.25 C ANISOU 3879 CB ARG D 479 2115 2880 2318 131 225 -348 C ATOM 3880 CG ARG D 479 52.436 1.937 -7.217 1.00 19.34 C ANISOU 3880 CG ARG D 479 2015 3018 2313 163 334 -376 C ATOM 3881 CD ARG D 479 51.652 3.264 -7.152 1.00 22.05 C ANISOU 3881 CD ARG D 479 2332 3364 2683 298 368 -442 C ATOM 3882 NE ARG D 479 50.213 3.019 -7.118 1.00 23.03 N ANISOU 3882 NE ARG D 479 2316 3626 2807 332 477 -475 N ATOM 3883 CZ ARG D 479 49.448 2.766 -8.182 1.00 24.23 C ANISOU 3883 CZ ARG D 479 2306 3868 3033 347 466 -451 C ATOM 3884 NH1 ARG D 479 49.944 2.768 -9.423 1.00 22.96 N ANISOU 3884 NH1 ARG D 479 2127 3672 2923 344 360 -392 N ATOM 3885 NH2 ARG D 479 48.161 2.542 -7.998 1.00 26.72 N ANISOU 3885 NH2 ARG D 479 2471 4316 3365 367 563 -491 N ATOM 3886 C ARG D 479 56.113 3.010 -8.047 1.00 18.00 C ANISOU 3886 C ARG D 479 2000 2531 2310 11.

60. 286 C ATOM 3887 O ARG D 479 56.893 2.152 -8.450 1.00 17.43 O ANISOU 3887 O ARG D 479 1902 2452 2268 4.

31. 230 O ATOM 3888 N VAL D 480 56.506 4.091 -7.376 1.00 18.88 N ANISOU 3888 N VAL D 480 2194 2547 2431 13.

13. 340 N ATOM 3889 CA VAL D 480 57.872 4.288 -6.941 1.00 18.12 C ANISOU 3889 CA VAL D 480 2153 2351 2382.

77. 95 -341 C ATOM 3890 CB VAL D 480 58.424 5.658 -7.477 1.00 19.53 C ANISOU 3890 CB VAL D 480 2339 2392 268.

91. 137 -344 C ATOM 3891 CG1 VAL D 480 59.811 6.004 -6.914 1.00 16.90 C ANISOU 3891 CG1 VAL D 480 2041 1951 243.

9. 261 -368 C ATOM 3892 CG2 VAL D 480 58.462 5.665 -8.979 1.00 16.55 C ANISOU 3892 CG2 VAL D 480 1871 2019 239.

100. 88 -246 C ATOM 3893 C VAL D 480 57.914 4.199 -5.402 1.00 20.38 C ANISOU 3893 C VAL D 480 2561 2642 254.

65. 138 -419 C ATOM 3894 O VAL D 480 57.129 4.864 -4.687 1.00 20.96 O ANISOU 3894 O VAL D 480 2713 2720 2531 126 -92 -507 O ATOM 3895 N SER D 481 58.821 3.365 -4.894 1.00 20.39 N ANISOU 3895 N SER D 481 2584 2645 2517 1 -225 -387 N ATOM 3896 CA SER D 481 59.058 3.257 -3.454 1.00 22.99 C ANISOU 3896 CA SER D 481 3052 2978 2703 -11 -302 -444 C ATOM 3897 CB SER D 481 59.874 1.996 -3.174 1.00 22.03 C ANISOU 3897 CB SER D 481 2928 2881 2562 -61 -385 -362 C ATOM 3898 OG SER D 481 60.138 1.858 -1.810 1.00 21.23 O ANISOU 3898 OG SER D 481 2978 2789 2300 -66 -480 -399 O ATOM 3899 C SER D 481 59.757 4.490 -2.835 1.00 25.71 C ANISOU 3899 C SER D 481 3483 3214 3072 -19 -429 -546 C ATOM 3900 O SER D 481 60.658 5.061 -3.420 1.00 25.93 O ANISOU 3900 O SER D 481 3439 3147 3265 -59 -511 -535 O ATOM 3901 N LYS D 482 59.321 4.900 -1.655 1.00 29.14 N ANISOU 3901 N LYS D 482 4076 3658 333.

13. 436 -651 N ATOM 3902 CA LYS D 482 60.019 5.935 -0.899 1.00 33.36 C ANISOU 3902 CA LYS D 482 4723 4086 3866 -7 -583 -772 C ATOM 3903 CB LYS D 482 59.022 6.840 -0.155 1.00 34.30 C ANISOU 3903 CB LYS D 482 4994 4191 384.

75. 492 -915 C ATOM 3904 CG LYS D 482 58.218 7.746 -1.062 1.00 35.12 C ANISOU 3904 CG LYS D 482 5025 4233 4086 151 -361 -933 C ATOM 3905 CD LYS D 482 57.186 8.541 -0.242 1.00 38.57 C ANISOU 3905 CD LYS D 482 5604 4663 4387 260 -254 -1083 C ATOM 3906 CE LYS D 482 57.252 10.056 -0.537 1.00 45.10 C ANISOU 3906 CE LYS D 482 6478 5298 5359 308 -284 -1185 C ATOM 3907 NZ LYS D 482 56.099 10.810 0.069 1.00 47.81 N ANISOU 3907 NZ LYS D 482 6933 5632 5603 453 -143 -1329 N ATOM 3908 C LYS D 482 61.038 5.332 0.072 1.00 35.24 C ANISOU 3908 C LYS D 482 5039 4343 4008 -65 -774 -772 C ATOM 3909 O LYS D 482 61.727 6.074 0.758 1.00 37.45 O ANISOU 3909 O LYS D 482 5410 4546 4275 -99 -937 -880 O ATOM 3910 N MSE D 483 61.139 3.993 0.102 1.00 35.93 N ANISOU 3910 N MSE D 483 5093 4523 4037 -74 -766 -651 N ATOM 3911 CA MSE D 483 62.049 3.244 0.994 1.00 38.63 C ANISOU 3911 CA MSE D 483 5507 4890 4278 -103 -953 -617 C ATOM 3912 CB MSE D 483 61.526 1.809 1.265 1.00 38.49 C ANISOU 3912 CB MSE D 483 5539 4971 4113 -80 -858 -492 C ATOM 3913 CG MSE D 483 60.174 1.672 1.929 1.00 38.95 C ANISOU 3913 CG MSE D 483 5746 5112 3940 -43 -667 -517 C ATOM 3914 SE MSE D 483 60.058 2.796 3.498 0.90 48.19 SE ANISOU 3914 SE MSE D 483 7190 6282 4839 -11 -748 -705 SE ATOM 3915 CE MSE D 483 61.347 1.963 4.722 1.00 38.88 C ANISOU 3915 CE MSE D 483 6178 5122 3472 -35 -1049 -643 C ATOM 3916 C MSE D 483 63.440 3.077 0.385 1.00 39.71 C ANISOU 3916 C MSE D 483 5470 4969 4647 -156 -1120 -557 C ATOM 3917 O MSE D 483 63.582 2.646 -0.783 1.00 39.13 O ANISOU 3917 O MSE D 483 5221 4891 4756 -163 -1031 -463 O ATOM 3918 OXT MSE D 483 64.451 3.268 1.060 1.00 42.00 O ANISOU 3918 OXT MSE D 483 5786 5231 4942 -190 -1344 -601 O ATOM 3919 N SER E 320 17.288 -30.979 -15.413 1.00 45.14 N ANISOU 3919 N SER E 320 4874 5333 6943 -1348 253 -1314 N ATOM 3920 CA SER E 320 18.777 -31.109 -15.580 1.00 43.13 C ANISOU 3920 CA SER E 320 4877 4914 6598 -1261 271 -1210 C ATOM 3921 CB SER E 320 19.237 -30.250 -16.770 1.00 42.79 C ANISOU 3921 CB SER E 320 4873 4954 6429 -1088 116 -1208 C ATOM 3922 OG SER E 320 20.570 -30.562 -17.153 1.00 42.94 O ANISOU 3922 OG SER E 320 5102 4848 6364 -1042 136 -1161 O ATOM 3923 C SER E 320 19.579 -30.728 -14.308 1.00 40.67 C ANISOU 3923 C SER E 320 4675 4506 6270 -1199 402 -1051 C ATOM 3924 O SER E 320 20.651 -30.104 -14.400 1.00 38.93 O ANISOU 3924 O SER E 320 4584 4241 5966 -1052 384 -962 O ATOM 3925 N SER E 321 19.089 -31.107 -13.126 1.00 39.80 N ANISOU 3925 N SER E 321 4515 4379 6227 -1326 537 -1019 N ATOM 3926 CA SER E 321 19.714 -30.590 -11.897 1.00 37.65 C ANISOU 3926 CA SER E 321 4321 4074 5908 -1264 645 -884 C ATOM 3927 CB SER E 321 18.684 -29.870 -11.033 1.00 38.56 C ANISOU 3927 CB SER E 321 4239 4357 6053 -1282 719 -919 C ATOM 3928 OG SER E 321 17.883 -30.781 -10.335 1.00 42.51 O ANISOU 3928 OG SER E 321 4667 4871 6613 -1506 844 -940 O ATOM 3929 C SER E 321 20.577 -31.528 -11.043 1.00 35.74 C ANISOU 3929 C SER E 321 4273 3651 5656 -1347 751 -758 C ATOM 3930 O SER E 321 20.985 -31.157 -9.954 1.00 35.15 O ANISOU 3930 O SER E 321 4249 3580 5525 -1318 835 -651 O ATOM 3931 N SER E 322 20.888 -32.716 -11.566 1.00 34.84 N ANISOU 3931 N SER E 322 4269 3374 5595 -1437 733 -776 N ATOM 3932 CA SER E 322 21.599 -33.753 -10.828 1.00 33.04 C ANISOU 3932 CA SER E 322 4224 2938 5393 -1514 809 -653 C ATOM 3933 CB SER E 322 20.570 -34.509 -9.996 1.00 35.56 C ANISOU 3933 CB SER E 322 4485 3245 5779 -1754 925 -626 C ATOM 3934 OG SER E 322 21.115 -35.024 -8.821 1.00 37.24 O ANISOU 3934 OG SER E 322 4855 3332 5961 -1811 1016 -441 O ATOM 3935 C SER E 322 22.235 -34.682 -11.863 1.00 31.91 C ANISOU 3935 C SER E 322 4198 2615 5311 -1502 734 -725 C ATOM 3936 O SER E 322 21.534 -35.240 -12.700 1.00 32.42 O ANISOU 3936 O SER E 322 4194 2677 5448 -1608 693 -870 O ATOM 3937 N PHE E 323 23.554 -34.840 -11.834 1.00 29.63 N ANISOU 3937 N PHE E 323 4068 2192 4996 -1371 715 -650 N ATOM 3938 CA PHE E 323 24.244 -35.599 -12.891 1.00 29.75 C ANISOU 3938 CA PHE E 323 4174 2063 5065 -1325 650 -758 C ATOM 3939 CB PHE E 323 24.149 -34.903 -14.263 1.00 28.38 C ANISOU 3939 CB PHE E 323 3911 2061 4813 -1241 558 -915 C ATOM 3940 CG PHE E 323 24.548 -33.447 -14.229 1.00 26.56 C ANISOU 3940 CG PHE E 323 3636 2007 4449 -1083 532 -845 C ATOM 3941 CD1 PHE E 323 25.862 -33.076 -14.466 1.00 22.90 C ANISOU 3941 CD1 PHE E 323 3264 1521 3918 -932 519 -808 C ATOM 3942 CE1 PHE E 323 26.235 -31.770 -14.412 1.00 24.39 C ANISOU 3942 CE1 PHE E 323 3422 1843 4002 -815 501 -741 C ATOM 3943 CZ PHE E 323 25.292 -30.792 -14.111 1.00 23.48 C ANISOU 3943 CZ PHE E 323 3191 1869 3862 -821 488 -715 C ATOM 3944 CE2 PHE E 323 23.978 -31.148 -13.862 1.00 24.40 C ANISOU 3944 CE2 PHE E 323 3199 2025 4048 -947 500 -764 C ATOM 3945 CD2 PHE E 323 23.615 -32.469 -13.928 1.00 24.02 C ANISOU 3945 CD2 PHE E 323 3176 1861 4091 -1090 526 -826 C ATOM 3946 C PHE E 323 25.685 -35.852 -12.537 1.00 29.09 C ANISOU 3946 C PHE E 323 4245 1828 4982 -1184 651 -658 C ATOM 3947 O PHE E 323 26.186 -35.304 -11.578 1.00 27.33 O ANISOU 3947 O PHE E 323 4053 1639 4692 -1113 681 -508 O ATOM 3948 N SER E 324 26.322 -36.718 -13.318 1.00 31.14 N ANISOU 3948 N SER E 324 4586 1925 5321 -1147 614 -765 N ATOM 3949 CA SER E 324 27.734 -37.036 -13.197 1.00 31.70 C ANISOU 3949 CA SER E 324 4771 1855 5418 -989 600 -719 C ATOM 3950 CB SER E 324 27.870 -38.553 -13.286 1.00 34.12 C ANISOU 3950 CB SER E 324 5192 1860 5913 -1047 596 -770 C ATOM 3951 OG SER E 324 29.065 -38.980 -12.669 1.00 38.99 O ANISOU 3951 OG SER E 324 5921 2300 6591 -905 581 -655 O ATOM 3952 C SER E 324 28.506 -36.359 -14.344 1.00 30.11 C ANISOU 3952 C SER E 324 4525 1797 5118 -844 560 -855 C ATOM 3953 O SER E 324 28.106 -36.436 -15.500 1.00 31.59 O ANISOU 3953 O SER E 324 4663 2058 5282 -883 530 -1033 O ATOM 3954 N PHE E 325 29.598 -35.683 -14.036 1.00 28.89 N ANISOU 3954 N PHE E 325 4383 1701 4891 -694 561 -773 N ATOM 3955 CA PHE E 325 30.474 -35.145 -15.073 1.00 27.03 C ANISOU 3955 CA PHE E 325 4117 1587 4568 -576 545 -888 C ATOM 3956 CB PHE E 325 30.028 -33.721 -15.485 1.00 25.71 C ANISOU 3956 CB PHE E 325 3861 1671 4236 -581 531 -870 C ATOM 3957 CG PHE E 325 30.847 -33.123 -16.611 1.00 24.39 C ANISOU 3957 CG PHE E 325 3676 1643 3950 -499 524 -964 C ATOM 3958 CD1 PHE E 325 30.800 -33.667 -17.896 1.00 26.53 C ANISOU 3958 CD1 PHE E 325 3946 1946 4189 -527 510 -1154 C ATOM 3959 CE1 PHE E 325 31.557 -33.143 -18.941 1.00 26.12 C ANISOU 3959 CE1 PHE E 325 3882 2048 3996 -474 523 -1236 C ATOM 3960 CZ PHE E 325 32.370 -32.062 -18.716 1.00 25.88 C ANISOU 3960 CZ PHE E 325 3837 2119 3876 -402 549 -1121 C ATOM 3961 CE2 PHE E 325 32.432 -31.495 -17.417 1.00 23.76 C ANISOU 3961 CE2 PHE E 325 3565 1800 3661 -371 553 -942 C ATOM 3962 CD2 PHE E 325 31.668 -32.040 -16.383 1.00 22.30 C ANISOU 3962 CD2 PHE E 325 3395 1484 3596 -415 540 -870 C ATOM 3963 C PHE E 325 31.902 -35.144 -14.575 1.00 26.40 C ANISOU 3963 C PHE E 325 4074 1446 4509 -425 553 -823 C ATOM 3964 O PHE E 325 32.194 -34.540 -13.538 1.00 26.23 O ANISOU 3964 O PHE E 325 4054 1463 4449 -387 556 -660 O ATOM 3965 N GLY E 326 32.796 -35.792 -15.322 1.00 27.37 N ANISOU 3965 N GLY E 326 4212 1496 4692 -336 554 -970 N ATOM 3966 CA GLY E 326 34.235 -35.778 -15.041 1.00 26.54 C ANISOU 3966 CA GLY E 326 4100 1366 4617 -174 556 -952 C ATOM 3967 C GLY E 326 34.617 -36.415 -13.719 1.00 27.28 C ANISOU 3967 C GLY E 326 4264 1264 4837 -114 519 -785 C ATOM 3968 O GLY E 326 35.626 -36.061 -13.130 1.00 26.73 O ANISOU 3968 O GLY E 326 4170 1232 4755 5 500 -704 O ATOM 3969 N GLY E 327 33.802 -37.361 -13.255 1.00 28.74 N ANISOU 3969 N GLY E 327 4538 1245 5136 -209 504 -726 N ATOM 3970 CA GLY E 327 34.068 -38.077 -12.017 1.00 29.31 C ANISOU 3970 CA GLY E 327 4711 1111 5316 -173 461 -535 C ATOM 3971 C GLY E 327 33.462 -37.392 -10.811 1.00 28.45 C ANISOU 3971 C GLY E 327 4617 1109 5084 -268 472 -313 C ATOM 3972 O GLY E 327 33.702 -37.801 -9.695 1.00 29.85 O ANISOU 3972 O GLY E 327 4879 1173 5289 -249 436 -125 O ATOM 3973 N PHE E 328 32.672 -36.346 -11.040 1.00 27.12 N ANISOU 3973 N PHE E 328 4367 1164 4775 -365 519 -340 N ATOM 3974 CA PHE E 328 32.019 -35.572 -9.968 1.00 26.05 C ANISOU 3974 CA PHE E 328 4218 1162 4519 -453 548 -181 C ATOM 3975 CB PHE E 328 32.455 -34.102 -10.014 1.00 23.69 C ANISOU 3975 CB PHE E 328 3822 1103 4075 -380 554 -197 C ATOM 3976 CG PHE E 328 33.877 -33.872 -9.572 1.00 23.60 C ANISOU 3976 CG PHE E 328 3813 1108 4048 -226 510 -147 C ATOM 3977 CD1 PHE E 328 34.167 -33.591 -8.245 1.00 22.43 C ANISOU 3977 CD1 PHE E 328 3694 1000 3828 -211 488 14 C ATOM 3978 CE1 PHE E 328 35.475 -33.394 -7.831 1.00 23.44 C ANISOU 3978 CE1 PHE E 328 3804 1160 3943 -72 429 48 C ATOM 3979 CZ PHE E 328 36.506 -33.431 -8.745 1.00 21.73 C ANISOU 3979 CZ PHE E 328 3523 942 3793 50 409 -84 C ATOM 3980 CE2 PHE E 328 36.228 -33.706 -10.080 1.00 22.34 C ANISOU 3980 CE2 PHE E 328 3575 984 3929 31 451 -248 C ATOM 3981 CD2 PHE E 328 34.921 -33.932 -10.485 1.00 21.48 C ANISOU 3981 CD2 PHE E 328 3500 839 3823 -105 492 -276 C ATOM 3982 C PHE E 328 30.497 -35.621 -10.086 1.00 26.19 C ANISOU 3982 C PHE E 328 4206 1214 4532 -642 600 -207 C ATOM 3983 O PHE E 328 29.950 -35.431 -11.172 1.00 26.07 O ANISOU 3983 O PHE E 328 4118 1269 4517 -682 603 -365 O ATOM 3984 N THR E 329 29.819 -35.857 -8.968 1.00 26.51 N ANISOU 3984 N THR E 329 4290 1228 4553 -764 638 -54 N ATOM 3985 CA THR E 329 28.360 -35.708 -8.900 1.00 26.59 C ANISOU 3985 CA THR E 329 4228 1329 4544 -949 705 -80 C ATOM 3986 CB THR E 329 27.755 -36.554 -7.740 1.00 28.57 C ANISOU 3986 CB THR E 329 4571 1463 4820 -1117 762 93 C ATOM 3987 OG1 THR E 329 28.147 -37.920 -7.876 1.00 29.01 O ANISOU 3987 OG1 THR E 329 4767 1221 5033 -1129 723 133 O ATOM 3988 CG2 THR E 329 26.239 -36.497 -7.744 1.00 28.98 C ANISOU 3988 CG2 THR E 329 4518 1619 4875 -1326 845 36 C ATOM 3989 C THR E 329 28.025 -34.221 -8.688 1.00 25.15 C ANISOU 3989 C THR E 329 3921 1415 4220 -919 731 -98 C ATOM 3990 O THR E 329 28.444 -33.613 -7.696 1.00 24.93 O ANISOU 3990 O THR E 329 3907 1473 4091 -873 746 12 O ATOM 3991 N PHE E 330 27.315 -33.629 -9.642 1.00 24.51 N ANISOU 3991 N PHE E 330 3721 1458 4135 -936 723 -244 N ATOM 3992 CA PHE E 330 26.858 -32.240 -9.556 1.00 23.01 C ANISOU 3992 CA PHE E 330 3410 1483 3850 -900 734 -274 C ATOM 3993 CB PHE E 330 26.817 -31.604 -10.941 1.00 21.72 C ANISOU 3993 CB PHE E 330 3173 1403 3676 -825 666 -409 C ATOM 3994 CG PHE E 330 28.177 -31.190 -11.498 1.00 21.21 C ANISOU 3994 CG PHE E 330 3166 1329 3566 -677 621 -415 C ATOM 3995 CD1 PHE E 330 28.458 -29.852 -11.723 1.00 15.46 C ANISOU 3995 CD1 PHE E 330 2388 729 2756 -587 599 -415 C ATOM 3996 CE1 PHE E 330 29.657 -29.480 -12.246 1.00 17.14 C ANISOU 3996 CE1 PHE E 330 2641 946 2926 -487 576 -422 C ATOM 3997 CZ PHE E 330 30.629 -30.427 -12.567 1.00 16.73 C ANISOU 3997 CZ PHE E 330 2657 787 2913 -450 574 -450 C ATOM 3998 CE2 PHE E 330 30.376 -31.764 -12.358 1.00 17.20 C ANISOU 3998 CE2 PHE E 330 2768 698 3069 -508 583 -460 C ATOM 3999 CD2 PHE E 330 29.154 -32.149 -11.835 1.00 21.06 C ANISOU 3999 CD2 PHE E 330 3238 1164 3598 -632 606 -432 C ATOM 4000 C PHE E 330 25.453 -32.252 -9.007 1.00 24.29 C ANISOU 4000 C PHE E 330 3474 1732 4023 -1056 804 -281 C ATOM 4001 O PHE E 330 24.630 -33.022 -9.465 1.00 26.43 O ANISOU 4001 O PHE E 330 3710 1954 4378 -1183 811 -348 O ATOM 4002 N LYS E 331 25.180 -31.429 -7.999 1.00 24.67 N ANISOU 4002 N LYS E 331 3469 1917 3990 -1057 863 -230 N ATOM 4003 CA LYS E 331 23.812 -31.224 -7.513 1.00 26.44 C ANISOU 4003 CA LYS E 331 3552 2275 4217 -1188 945 -275 C ATOM 4004 CB LYS E 331 23.617 -31.802 -6.093 1.00 27.86 C ANISOU 4004 CB LYS E 331 3795 2455 4336 -1333 1061 -141 C ATOM 4005 CG LYS E 331 23.960 -33.297 -5.951 1.00 31.24 C ANISOU 4005 CG LYS E 331 4390 2659 4822 -1444 1064 -17 C ATOM 4006 CD LYS E 331 23.547 -33.844 -4.584 1.00 33.05 C ANISOU 4006 CD LYS E 331 4681 2905 4972 -1626 1184 138 C ATOM 4007 CE LYS E 331 23.640 -35.361 -4.566 1.00 38.36 C ANISOU 4007 CE LYS E 331 5513 3318 5742 -1762 1182 262 C ATOM 4008 NZ LYS E 331 22.905 -35.921 -3.365 1.00 42.80 N ANISOU 4008 NZ LYS E 331 6117 3916 6230 -2004 1321 413 N ATOM 4009 C LYS E 331 23.523 -29.732 -7.509 1.00 25.02 C ANISOU 4009 C LYS E 331 3240 2275 3994 -1072 934 -357 C ATOM 4010 O LYS E 331 24.129 -28.997 -6.727 1.00 24.10 O ANISOU 4010 O LYS E 331 3157 2208 3793 -994 956 -308 O ATOM 4011 N ARG E 332 22.604 -29.291 -8.370 1.00 25.04 N ANISOU 4011 N ARG E 332 3089 2363 4061 -1059 886 -484 N ATOM 4012 CA ARG E 332 22.229 -27.881 -8.446 1.00 24.35 C ANISOU 4012 CA ARG E 332 2874 2411 3969 -932 855 -562 C ATOM 4013 CB ARG E 332 21.285 -27.616 -9.610 1.00 25.25 C ANISOU 4013 CB ARG E 332 2839 2593 4163 -905 757 -680 C ATOM 4014 CG ARG E 332 21.014 -26.115 -9.816 1.00 21.87 C ANISOU 4014 CG ARG E 332 2303 2255 3752 -736 689 -736 C ATOM 4015 CD ARG E 332 20.462 -25.836 -11.209 1.00 20.39 C ANISOU 4015 CD ARG E 332 2030 2105 3611 -667 535 -801 C ATOM 4016 NE ARG E 332 19.065 -26.242 -11.251 1.00 24.14 N ANISOU 4016 NE ARG E 332 2301 2699 4172 -764 543 -916 N ATOM 4017 CZ ARG E 332 18.397 -26.578 -12.351 1.00 23.40 C ANISOU 4017 CZ ARG E 332 2117 2660 4116 -788 424 -991 C ATOM 4018 NH1 ARG E 332 18.988 -26.571 -13.538 1.00 21.11 N ANISOU 4018 NH1 ARG E 332 1938 2320 3762 -722 293 -959 N ATOM 4019 NH2 ARG E 332 17.126 -26.891 -12.252 1.00 20.98 N ANISOU 4019 NH2 ARG E 332 1594 2479 3898 -885 440 -1109 N ATOM 4020 C ARG E 332 21.525 -27.438 -7.198 1.00 26.32 C ANISOU 4020 C ARG E 332 3014 2794 4193 -986 977 -590 C ATOM 4021 O ARG E 332 20.536 -28.054 -6.779 1.00 27.98 O ANISOU 4021 O ARG E 332 3124 3075 4432 -1144 1068 -625 O ATOM 4022 N THR E 333 22.010 -26.355 -6.605 1.00 25.21 N ANISOU 4022 N THR E 333 2884 2698 3998 -869 988 -593 N ATOM 4023 CA THR E 333 21.397 -25.862 -5.375 1.00 26.76 C ANISOU 4023 CA THR E 333 2975 3042 4151 -911 1115 -652 C ATOM 4024 CB THR E 333 22.430 -25.785 -4.254 1.00 26.26 C ANISOU 4024 CB THR E 333 3060 2971 3947 -914 1174 -557 C ATOM 4025 OG1 THR E 333 23.540 -25.025 -4.725 1.00 26.60 O ANISOU 4025 OG1 THR E 333 3196 2922 3989 -755 1066 -537 O ATOM 4026 CG2 THR E 333 22.913 -27.195 -3.863 1.00 26.22 C ANISOU 4026 CG2 THR E 333 3215 2876 3869 -1058 1210 -394 C ATOM 4027 C THR E 333 20.663 -24.526 -5.541 1.00 26.87 C ANISOU 4027 C THR E 333 2805 3156 4249 -774 1087 -809 C ATOM 4028 O THR E 333 19.854 -24.162 -4.697 1.00 28.07 O ANISOU 4028 O THR E 333 2810 3455 4401 -809 1199 -916 O ATOM 4029 N SER E 334 20.951 -23.808 -6.627 1.00 26.17 N ANISOU 4029 N SER E 334 2727 2986 4232 -617 940 -820 N ATOM 4030 CA SER E 334 20.279 -22.542 -6.963 1.00 27.33 C ANISOU 4030 CA SER E 334 2719 3177 4488 -459 871 -942 C ATOM 4031 CB SER E 334 21.102 -21.370 -6.495 1.00 26.24 C ANISOU 4031 CB SER E 334 2660 2977 4331 -331 863 -947 C ATOM 4032 OG SER E 334 20.687 -20.972 -5.253 1.00 30.33 O ANISOU 4032 OG SER E 334 3084 3610 4830 -352 996 -1061 O ATOM 4033 C SER E 334 20.227 -22.353 -8.446 1.00 27.14 C ANISOU 4033 C SER E 334 2699 3081 4532 -363 695 -914 C ATOM 4034 O SER E 334 21.097 -22.860 -9.148 1.00 24.82 O ANISOU 4034 O SER E 334 2565 2688 4175 -384 635 -806 O ATOM 4035 N GLY E 335 19.259 -21.545 -8.895 1.00 28.15 N ANISOU 4035 N GLY E 335 2651 3264 4780 -243 609 -1014 N ATOM 4036 CA GLY E 335 19.198 -21.137 -10.292 1.00 27.93 C ANISOU 4036 CA GLY E 335 2635 3180 4796 -127 415 -971 C ATOM 4037 C GLY E 335 18.565 -22.157 -11.198 1.00 28.12 C ANISOU 4037 C GLY E 335 2593 3273 4817 -224 346 -983 C ATOM 4038 O GLY E 335 17.901 -23.072 -10.736 1.00 29.23 O ANISOU 4038 O GLY E 335 2627 3506 4972 -375 446 -1053 O ATOM 4039 N SER E 336 18.775 -21.971 -12.500 1.00 28.38 N ANISOU 4039 N SER E 336 2694 3267 4823 -150 176 -918 N ATOM 4040 CA SER E 336 18.131 -22.753 -13.569 1.00 29.07 C ANISOU 4040 CA SER E 336 2710 3437 4900 -217.

65. 954 C ATOM 4041 CB SER E 336 16.621 -22.473 -13.635 1.00 31.46 C ANISOU 4041 CB SER E 336 2727 3891 5336 -168 -9 -1092 C ATOM 4042 OG SER E 336 16.347 -21.090 -13.798 1.00 31.69 O ANISOU 4042 OG SER E 336 2690 3901 545.

54. 132 -1084 O ATOM 4043 C SER E 336 18.788 -22.347 -14.882 1.00 28.45 C ANISOU 4043 C SER E 336 2781 3302 4725 -127 -102 -846 C ATOM 4044 O SER E 336 19.493 -21.345 -14.949 1.00 28.13 O ANISOU 4044 O SER E 336 2857 3166 4665 -7 -138 -747 O ATOM 4045 N SER E 337 18.584 -23.140 -15.920 1.00 28.83 N ANISOU 4045 N SER E 337 2834 3415 4705 -205 -194 -868 N ATOM 4046 CA SER E 337 19.123 -22.804 -17.221 1.00 28.54 C ANISOU 4046 CA SER E 337 2932 3371 4540 -140 -346 -774 C ATOM 4047 CB SER E 337 20.569 -23.278 -17.364 1.00 26.18 C ANISOU 4047 CB SER E 337 2866 2970 4113 -211 -249 -695 C ATOM 4048 OG SER E 337 20.653 -24.681 -17.263 1.00 28.38 O ANISOU 4048 OG SER E 337 3156 3248 4378 -372 -156 -782 O ATOM 4049 C SER E 337 18.249 -23.305 -18.353 1.00 29.78 C ANISOU 4049 C SER E 337 2982 3676 4656 -176 -510 -851 C ATOM 4050 O SER E 337 17.378 -24.160 -18.157 1.00 30.45 O ANISOU 4050 O SER E 337 2905 3849 4814 -290 -483 -990 O ATOM 4051 N ILE E 338 18.476 -22.729 -19.525 1.00 30.64 N ANISOU 4051 N ILE E 338 3181 3820 4639 -89 -681 -757 N ATOM 4052 CA ILE E 338 17.938 -23.221 -20.783 1.00 31.77 C ANISOU 4052 CA ILE E 338 3281 4120 4670 -132 -851 -814 C ATOM 4053 CB ILE E 338 17.005 -22.176 -21.446 1.00 33.98 C ANISOU 4053 CB ILE E 338 3438 4503 496.

41. 1101 -760 C ATOM 4054 CG1 ILE E 338 17.737 -20.850 -21.743 1.00 32.53 C ANISOU 4054 CG1 ILE E 338 3435 4204 4721 199 -1175 -540 C ATOM 4055 CD1 ILE E 338 16.899 -19.806 -22.508 1.00 34.27 C ANISOU 4055 CD1 ILE E 338 3577 4492 4952 387 -1453 -443 C ATOM 4056 CG2 ILE E 338 15.748 -21.966 -20.580 1.00 34.20 C ANISOU 4056 CG2 ILE E 338 3181 4582 5232 103 -1106 -883 C ATOM 4057 C ILE E 338 19.151 -23.626 -21.656 1.00 31.96 C ANISOU 4057 C ILE E 338 3543 4122 4476 -205 -826 -751 C ATOM 4058 O ILE E 338 20.274 -23.333 -21.307 1.00 29.56 O ANISOU 4058 O ILE E 338 3404 3692 4137 -193 -705 -650 O ATOM 4059 N LYS E 339 18.931 -24.339 -22.747 1.00 35.06 N ANISOU 4059 N LYS E 339 3939 4655 4729 -290 -928 -838 N ATOM 4060 CA LYS E 339 20.029 -24.773 -23.631 1.00 36.58 C ANISOU 4060 CA LYS E 339 4335 4861 4705 -363 -892 -821 C ATOM 4061 CB LYS E 339 20.084 -26.290 -23.805 1.00 36.71 C ANISOU 4061 CB LYS E 339 4342 4894 4712 -536 -805 -1027 C ATOM 4062 CG LYS E 339 20.066 -27.164 -22.598 1.00 37.43 C ANISOU 4062 CG LYS E 339 4380 4835 5006 -627 -622 -1118 C ATOM 4063 CD LYS E 339 19.853 -28.608 -23.095 1.00 40.71 C ANISOU 4063 CD LYS E 339 4778 5276 5414 -797 -606 -1331 C ATOM 4064 CE LYS E 339 19.579 -29.601 -21.976 1.00 42.52 C ANISOU 4064 CE LYS E 339 4945 5354 5856 -921 -452 -1418 C ATOM 4065 NZ LYS E 339 19.132 -30.907 -22.530 1.00 45.89 N ANISOU 4065 NZ LYS E 339 5332 5798 6308 -1093 -469 -1635 N ATOM 4066 C LYS E 339 19.787 -24.253 -25.032 1.00 39.73 C ANISOU 4066 C LYS E 339 4775 5437 4882 -315 -1112 -753 C ATOM 4067 O LYS E 339 18.632 -24.092 -25.473 1.00 41.88 O ANISOU 4067 O LYS E 339 4892 5855 5167 -273 -1310 -795 O ATOM 4068 N ARG E 340 20.885 -24.049 -25.745 1.00 40.42 N ANISOU 4068 N ARG E 340 5065 5535 4757 -334 -1077 -656 N ATOM 4069 CA ARG E 340 20.863 -23.611 -27.123 1.00 43.90 C ANISOU 4069 CA ARG E 340 5594 6160 4925 -320 -1258 -568 C ATOM 4070 CB ARG E 340 20.961 -22.081 -27.170 1.00 44.64 C ANISOU 4070 CB ARG E 340 5770 6188 5002 -170 -1365 -292 C ATOM 4071 CG ARG E 340 20.849 -21.453 -28.545 1.00 49.08 C ANISOU 4071 CG ARG E 340 6441 6929 5279 -142 -1581 -134 C ATOM 4072 CD ARG E 340 21.496 -20.082 -28.498 1.00 51.89 C ANISOU 4072 CD ARG E 340 6964 7138 5614 -49 -1589 158 C ATOM 4073 NE ARG E 340 21.220 -19.278 -29.683 1.00 56.36 N ANISOU 4073 NE ARG E 340 7638 7837 594.

5. 1831 373 N ATOM 4074 CZ ARG E 340 21.825 -18.121 -29.947 1.00 59.39 C ANISOU 4074 CZ ARG E 340 8212 8114 624.

48. 1858 658 C ATOM 4075 NH1 ARG E 340 22.748 -17.647 -29.115 1.00 56.32 N ANISOU 4075 NH1 ARG E 340 7907 7494 599.

38. 1655 729 N ATOM 4076 NH2 ARG E 340 21.514 -17.438 -31.051 1.00 63.84 N ANISOU 4076 NH2 ARG E 340 8887 8799 656.

90. 2097 878 N ATOM 4077 C ARG E 340 22.067 -24.271 -27.797 1.00 44.15 C ANISOU 4077 C ARG E 340 5797 6240 4738 -444 -1118 -630 C ATOM 4078 O ARG E 340 23.203 -24.110 -27.355 1.00 42.69 O ANISOU 4078 O ARG E 340 5728 5923 4568 -452 -937 -561 O ATOM 4079 N GLU E 341 21.819 -25.062 -28.834 1.00 46.84 N ANISOU 4079 N GLU E 341 6132 6780 4884 -542 -1197 -791 N ATOM 4080 CA GLU E 341 22.906 -25.647 -29.629 1.00 47.97 C ANISOU 4080 CA GLU E 341 6424 7010 4792 -651 -1074 -881 C ATOM 4081 CB GLU E 341 22.392 -26.781 -30.528 1.00 50.34 C ANISOU 4081 CB GLU E 341 6666 7504 4956 -770 -1150 -1154 C ATOM 4082 CG GLU E 341 23.492 -27.439 -31.354 1.00 53.33 C ANISOU 4082 CG GLU E 341 7181 7984 5099 -876 -1010 -1297 C ATOM 4083 CD GLU E 341 23.258 -28.925 -31.594 1.00 57.92 C ANISOU 4083 CD GLU E 341 7691 8590 5726 -998 -966 -1652 C ATOM 4084 OE1 GLU E 341 22.554 -29.280 -32.578 1.00 60.51 O ANISOU 4084 OE1 GLU E 341 7977 9149 5864 -1070 -1129 -1802 O ATOM 4085 OE2 GLU E 341 23.805 -29.734 -30.804 1.00 56.96 O ANISOU 4085 OE2 GLU E 341 7564 8249 5831 -1021 -776 -1779 O ATOM 4086 C GLU E 341 23.631 -24.578 -30.459 1.00 48.77 C ANISOU 4086 C GLU E 341 6704 7214 4614 -626 -1112 -642 C ATOM 4087 O GLU E 341 22.992 -23.827 -31.186 1.00 51.13 O ANISOU 4087 O GLU E 341 7019 7655 4752 -576 -1330 -491 O ATOM 4088 N GLU E 342 24.961 -24.539 -30.346 1.00 47.41 N ANISOU 4088 N GLU E 342 6657 6969 4389 -668 -901 -607 N ATOM 4089 CA GLU E 342 25.803 -23.487 -30.926 1.00 48.38 C ANISOU 4089 CA GLU E 342 6949 7146 4286 -674 -880 -363 C ATOM 4090 CB GLU E 342 26.214 -22.470 -29.845 1.00 46.46 C ANISOU 4090 CB GLU E 342 6731 6650 4270 -584 -806 -148 C ATOM 4091 CG GLU E 342 25.137 -21.435 -29.509 1.00 48.29 C ANISOU 4091 CG GLU E 342 6913 6795 4640 -445 -1019 45 C ATOM 4092 CD GLU E 342 25.495 -20.511 -28.349 1.00 45.94 C ANISOU 4092 CD GLU E 342 6626 6233 4596 -356 -937 198 C ATOM 4093 OE1 GLU E 342 24.616 -20.290 -27.494 1.00 46.26 O ANISOU 4093 OE1 GLU E 342 6536 6152 4889 -245 -1012 183 O ATOM 4094 OE2 GLU E 342 26.637 -19.996 -28.287 1.00 46.95 O ANISOU 4094 OE2 GLU E 342 6881 6288 4671 -406 -794 315 O ATOM 4095 C GLU E 342 27.072 -24.059 -31.538 1.00 48.22 C ANISOU 4095 C GLU E 342 7028 7239 4056 -797 -676 -486 C ATOM 4096 O GLU E 342 27.501 -25.153 -31.181 1.00 47.12 O ANISOU 4096 O GLU E 342 6828 7042 4033 -837 -521 -734 O ATOM 4097 N GLU E 343 27.682 -23.303 -32.446 1.00 49.43 N ANISOU 4097 N GLU E 343 7330 7543 3907 -857 -673 -307 N ATOM 4098 CA GLU E 343 28.980 -23.660 -32.998 1.00 49.39 C ANISOU 4098 CA GLU E 343 7407 7663 3698 -977 -452 -405 C ATOM 4099 CB GLU E 343 28.974 -23.575 -34.524 1.00 53.28 C ANISOU 4099 CB GLU E 343 8011 8493 3737 -1090 -528 -387 C ATOM 4100 CG GLU E 343 28.356 -24.787 -35.191 1.00 55.60 C ANISOU 4100 CG GLU E 343 8229 8984 3914 -1138 -598 -712 C ATOM 4101 CD GLU E 343 28.384 -24.690 -36.695 1.00 61.06 C ANISOU 4101 CD GLU E 343 9037 10045 4118 -1260 -671 -706 C ATOM 4102 OE1 GLU E 343 29.354 -24.119 -37.237 1.00 63.45 O ANISOU 4102 OE1 GLU E 343 9471 10471 4165 -1353 -536 -563 O ATOM 4103 OE2 GLU E 343 27.437 -25.188 -37.339 1.00 64.46 O ANISOU 4103 OE2 GLU E 343 9423 10659 4409 -1277 -862 -848 O ATOM 4104 C GLU E 343 30.096 -22.797 -32.435 1.00 47.41 C ANISOU 4104 C GLU E 343 7226 7262 3525 -983 -284 -209 C ATOM 4105 O GLU E 343 30.107 -21.573 -32.600 1.00 47.73 O ANISOU 4105 O GLU E 343 7377 7275 3484 -980 -360 94 O ATOM 4106 N VAL E 344 31.046 -23.454 -31.778 1.00 44.90 N ANISOU 4106 N VAL E 344 6843 6842 3375 -993 -63 -387 N ATOM 4107 CA VAL E 344 32.197 -22.761 -31.209 1.00 43.05 C ANISOU 4107 CA VAL E 344 6643 6486 3226 -1012 109 -252 C ATOM 4108 CB VAL E 344 32.331 -23.057 -29.702 1.00 39.90 C ANISOU 4108 CB VAL E 344 6131 5809 3220 -906 177 -321 C ATOM 4109 CG1 VAL E 344 31.101 -22.518 -28.950 1.00 38.32 C ANISOU 4109 CG1 VAL E 344 5899 5435 3226 -792 -14 -182 C ATOM 4110 CG2 VAL E 344 32.487 -24.553 -29.465 1.00 38.73 C ANISOU 4110 CG2 VAL E 344 5876 5650 3188 -889 269 -644 C ATOM 4111 C VAL E 344 33.490 -23.102 -31.963 1.00 44.32 C ANISOU 4111 C VAL E 344 6833 6849 3159 -1141 328 -377 C ATOM 4112 O VAL E 344 33.591 -24.158 -32.616 1.00 44.99 O ANISOU 4112 O VAL E 344 6878 7105 3111 -1182 386 -649 O ATOM 4113 N LEU E 345 34.471 -22.206 -31.883 1.00 43.87 N ANISOU 4113 N LEU E 345 6834 6773 3060 -1212 457 -199 N ATOM 4114 CA LEU E 345 35.747 -22.449 -32.550 1.00 45.58 C ANISOU 4114 CA LEU E 345 7050 7199 3071 -1345 689 -320 C ATOM 4115 CB LEU E 345 36.032 -21.390 -33.626 1.00 48.71 C ANISOU 4115 CB LEU E 345 7610 7796 3101 -1510 700 -58 C ATOM 4116 CG LEU E 345 35.431 -21.671 -35.017 1.00 53.49 C ANISOU 4116 CG LEU E 345 8310 8712 3302 -1592 600 -90 C ATOM 4117 CD1 LEU E 345 35.111 -20.382 -35.775 1.00 57.03 C ANISOU 4117 CD1 LEU E 345 8960 9243 3466 -1690 468 304 C ATOM 4118 CD2 LEU E 345 36.333 -22.561 -35.889 1.00 56.50 C ANISOU 4118 CD2 LEU E 345 8642 9402 3424 -1714 825 -394 C ATOM 4119 C LEU E 345 36.896 -22.595 -31.559 1.00 43.09 C ANISOU 4119 C LEU E 345 6618 6736 3019 -1317 884 -414 C ATOM 4120 O LEU E 345 37.045 -21.789 -30.628 1.00 41.78 O ANISOU 4120 O LEU E 345 6453 6357 3066 -1279 869 -231 O ATOM 4121 N THR E 346 37.683 -23.651 -31.742 1.00 42.92 N ANISOU 4121 N THR E 346 6486 6827 2994 -1323 1054 -721 N ATOM 4122 CA THR E 346 38.811 -23.942 -30.852 1.00 41.13 C ANISOU 4122 CA THR E 346 6122 6488 3017 -1274 1224 -845 C ATOM 4123 CB THR E 346 39.287 -25.407 -30.977 1.00 40.99 C ANISOU 4123 CB THR E 346 5972 6534 3070 -1207 1337 -1229 C ATOM 4124 OG1 THR E 346 39.774 -25.630 -32.308 1.00 42.56 O ANISOU 4124 OG1 THR E 346 6186 7057 2929 -1338 1471 -1380 O ATOM 4125 CG2 THR E 346 38.155 -26.375 -30.640 1.00 38.07 C

ANISOU 4125 CG2 THR E 346 5595 6009 2863 -1084 1175 -1361

ATOM 4126 C THR E 346 39.986 -23.035 -31.189 1.00 43.36 C

ANISOU 4126 C THR E 346 6415 6908 3153 -1428 1402 -722 C

ATOM 4127 O THR E 346 40.054 -22.483 -32.302 1.00 45.98 O

ANISOU 4127 O THR E 346 6857 7467 3144 -1588 1441 -607 O

ATOM 4128 N GLY E 347 40.919 -22.907 -30.244 1.00 42.34 N

ANISOU 4128 N GLY E 347 6167 6654 3267 -1393 1511 -749 N

ATOM 4129 CA GLY E 347 42.178 -22.198 -30.484 1.00 44.62 C

ANISOU 4129 CA GLY E 347 6414 7080 3459 -1551 1710 -693 C

ATOM 4130 C GLY E 347 42.936 -22.690 -31.716 1.00 48.49 C

ANISOU 4130 C GLY E 347 6856 7916 3651 -1680 1913 -899 C

ATOM 4131 O GLY E 347 43.950 -22.101 -32.104 1.00 50.47 O

ANISOU 4131 O GLY E 347 7071 8338 3766 -1851 2101 -856 O

ATOM 4132 N ASN E 348 42.442 -23.772 -32.316 1.00 49.38 N

ANISOU 4132 N ASN E 348 6961 8138 3665 -1611 1882 -1139 N

ATOM 4133 CA ASN E 348 43.017 -24.343 -33.522 1.00 53.66 C

ANISOU 4133 CA ASN E 348 7459 9021 3906 -1720 2064 -1385 C

ATOM 4134 CB ASN E 348 43.303 -25.835 -33.302 1.00 53.90 C

ANISOU 4134 CB ASN E 348 7316 9024 4141 -1548 2123 -1804 C

ATOM 4135 CG ASN E 348 44.284 -26.389 -34.308 1.00 57.89 C

ANISOU 4135 CG ASN E 348 7705 9868 4422 -1639 2373 -2119 C

ATOM 4136 OD1 ASN E 348 45.044 -25.643 -34.912 1.00 61.94 O

ANISOU 4136 OD1 ASN E 348 8216 10630 4689 -1832 2550 -2031 O

ATOM 4137 ND2 ASN E 348 44.272 -27.699 -34.497 1.00 59.86 N

ANISOU 4137 ND2 ASN E 348 7856 10127 4760 -1508 2399 -2498 N

ATOM 4138 C ASN E 348 42.113 -24.173 -34.739 1.00 55.81 C

ANISOU 4138 C ASN E 348 7918 9505 3784 -1834 1968 -1293 C

ATOM 4139 O ASN E 348 42.448 -24.620 -35.833 1.00 59.14 O

ANISOU 4139 O ASN E 348 8330 10245 3896 -1941 2104 -1495 O

ATOM 4140 N LEU E 349 40.962 -23.532 -34.544 1.00 54.75 N

ANISOU 4140 N LEU E 349 7942 9207 3654 -1805 1726 -1000 N

ATOM 4141 CA LEU E 349 39.927 -23.424 -35.585 1.00 56.68 C

ANISOU 4141 CA LEU E 349 8352 9623 3560 -1871 1566 -904 C

ATOM 4142 CB LEU E 349 40.470 -22.725 -36.850 1.00 60.70 C

ANISOU 4142 CB LEU E 349 8981 10485 3599 -2117 1702 -766 C

ATOM 4143 CG LEU E 349 41.305 -21.440 -36.688 1.00 61.95 C

ANISOU 4143 CG LEU E 349 9196 10613 3728 -2277 1827 -450 C

ATOM 4144 CD1 LEU E 349 42.160 -21.185 -37.940 1.00 65.27 C

ANISOU 4144 CD1 LEU E 349 9667 11441 3693 -2540 2062 -454 C

ATOM 4145 CD2 LEU E 349 40.447 -20.215 -36.321 1.00 60.69 C

ANISOU 4145 CD2 LEU E 349 9223 10201 3636 -2262 1587 -7 C

ATOM 4146 C LEU E 349 39.218 -24.767 -35.944 1.00 56.66 C

ANISOU 4146 C LEU E 349 8297 9686 3545 -1769 1484 -1246 C

ATOM 4147 O LEU E 349 38.866 -24.994 -37.106 1.00 59.07 O

ANISOU 4147 O LEU E 349 8682 10278 3484 -1869 1460 -1327 O

ATOM 4148 N GLN E 350 39.005 -25.636 -34.947 1.00 53.61 N

ANISOU 4148 N GLN E 350 7787 9033 3550 -1586 1436 -1439 N

ATOM 4149 CA GLN E 350 38.133 -26.811 -35.108 1.00 53.10 C

ANISOU 4149 CA GLN E 350 7691 8940 3543 -1494 1316 -1711 C

ATOM 4150 CB GLN E 350 38.663 -28.028 -34.332 1.00 51.62 C

ANISOU 4150 CB GLN E 350 7339 8560 3716 -1348 1419 -2042 C

ATOM 4151 CG GLN E 350 37.873 -29.328 -34.565 1.00 52.67 C

ANISOU 4151 CG GLN E 350 7445 8647 3921 -1280 1324 -2357 C

ATOM 4152 CD GLN E 350 38.338 -30.499 -33.702 1.00 50.84 C

ANISOU 4152 CD GLN E 350 7077 8154 4087 -1123 1397 -2632 C

ATOM 4153 OE1 GLN E 350 39.291 -30.387 -32.937 1.00 49.10 O

ANISOU 4153 OE1 GLN E 350 6767 7811 4078 -1049 1513 -2603 O

ATOM 4154 NE2 GLN E 350 37.658 -31.631 -33.831 1.00 50.04 N

ANISOU 4154 NE2 GLN E 350 6962 7961 4090 -1076 1317 -2896 N

ATOM 4155 C GLN E 350 36.738 -26.435 -34.620 1.00 51.00 C

ANISOU 4155 C GLN E 350 7502 8477 3398 -1419 1039 -1482 C

ATOM 4156 O GLN E 350 36.586 -25.851 -33.553 1.00 48.42 O

ANISOU 4156 O GLN E 350 7168 7889 3341 -1337 973 -1266 O

ATOM 4157 N THR E 351 35.720 -26.751 -35.413 1.00 52.50 N

ANISOU 4157 N THR E 351 7754 8813 3381 -1451 877 -1545 N ATOM 4158 CA THR E 351 34.345 -26.457 -35.043 1.00 51.35 C ANISOU 4158 CA THR E 351 7647 8521 3345 -1378 610 -1367 C ATOM 4159 CB THR E 351 33.426 -26.373 -36.272 1.00 54.37 C ANISOU 4159 CB THR E 351 8122 9185 3350 -1464 430 -1351 C ATOM 4160 OG1 THR E 351 33.904 -25.359 -37.160 1.00 57.38 O ANISOU 4160 OG1 THR E 351 8642 9811 3347 -1597 470 -1106 O ATOM 4161 CG2 THR E 351 31.995 -26.030 -35.851 1.00 54.10 C ANISOU 4161 CG2 THR E 351 8091 9006 3461 -1372 144 -1173 C ATOM 4162 C THR E 351 33.814 -27.529 -34.107 1.00 48.97 C ANISOU 4162 C THR E 351 7225 7955 3425 -1251 560 -1586 C ATOM 4163 O THR E 351 33.904 -28.716 -34.421 1.00 49.72 O ANISOU 4163 O THR E 351 7258 8093 3539 -1254 623 -1930 O ATOM 4164 N LEU E 352 33.273 -27.098 -32.966 1.00 45.92 N ANISOU 4164 N LEU E 352 6814 7296 3339 -1150 455 -1389 N ATOM 4165 CA LEU E 352 32.556 -27.983 -32.059 1.00 44.43 C ANISOU 4165 CA LEU E 352 6531 6865 3485 -1055 383 -1532 C ATOM 4166 CB LEU E 352 33.221 -28.020 -30.676 1.00 41.32 C ANISOU 4166 CB LEU E 352 6073 6188 3439 -957 494 -1483 C ATOM 4167 CG LEU E 352 34.668 -28.498 -30.506 1.00 41.46 C ANISOU 4167 CG LEU E 352 6040 6188 3524 -941 718 -1642 C ATOM 4168 CD1 LEU E 352 35.062 -28.343 -29.037 1.00 38.52 C ANISOU 4168 CD1 LEU E 352 5612 5540 3485 -837 755 -1527 C ATOM 4169 CD2 LEU E 352 34.921 -29.937 -30.990 1.00 42.58 C ANISOU 4169 CD2 LEU E 352 6127 6363 3689 -938 799 -2023 C ATOM 4170 C LEU E 352 31.099 -27.545 -31.923 1.00 44.26 C ANISOU 4170 C LEU E 352 6514 6808 3497 -1026 139 -1372 C ATOM 4171 O LEU E 352 30.819 -26.372 -31.696 1.00 43.64 O ANISOU 4171 O LEU E 352 6483 6697 3400 -997.

47. 1074 O ATOM 4172 N LYS E 353 30.182 -28.496 -32.077 1.00 45.32 N ANISOU 4172 N LYS E 353 6585 6943 3691 -1035.

36. 1586 N ATOM 4173 CA LYS E 353 28.773 -28.271 -31.800 1.00 45.51 C ANISOU 4173 CA LYS E 353 6559 6921 3812 -1002 -182 -1491 C ATOM 4174 CB LYS E 353 27.921 -29.158 -32.701 1.00 47.91 C ANISOU 4174 CB LYS E 353 6823 7400 3979 -1081 -305 -1748 C ATOM 4175 CG LYS E 353 26.524 -28.628 -33.009 1.00 50.14 C ANISOU 4175 CG LYS E 353 7063 7798 4190 -1071 -572 -1626 C ATOM 4176 CD LYS E 353 25.789 -29.583 -33.964 1.00 53.59 C ANISOU 4176 CD LYS E 353 7450 8440 4472 -1172 -688 -1924 C ATOM 4177 CE LYS E 353 24.859 -28.824 -34.921 1.00 59.05 C ANISOU 4177 CE LYS E 353 8155 9414 4866 -1182 -955 -1782 C ATOM 4178 NZ LYS E 353 24.338 -29.667 -36.045 1.00 61.33 N ANISOU 4178 NZ LYS E 353 8416 9973 4912 -1300 -1066 -2081 N ATOM 4179 C LYS E 353 28.524 -28.604 -30.336 1.00 42.55 C ANISOU 4179 C LYS E 353 6095 6234 3837 -922 -146 -1482 C ATOM 4180 O LYS E 353 28.662 -29.747 -29.922 1.00 42.17 O ANISOU 4180 O LYS E 353 5995 6049 3977 -931 -59 -1705 O ATOM 4181 N ILE E 354 28.186 -27.597 -29.545 1.00 41.27 N ANISOU 4181 N ILE E 354 5923 5956 3801 -845 -209 -1222 N ATOM 4182 CA ILE E 354 27.891 -27.795 -28.136 1.00 39.35 C ANISOU 4182 CA ILE E 354 5599 5456 3897 -780 -175 -1195 C ATOM 4183 CB ILE E 354 28.992 -27.170 -27.205 1.00 37.50 C ANISOU 4183 CB ILE E 354 5404 5064 3781 -718 -28 -1037 C ATOM 4184 CG1 ILE E 354 29.069 -25.650 -27.368 1.00 37.51 C ANISOU 4184 CG1 ILE E 354 5473 5114 3665 -685 -92 -761 C ATOM 4185 CD1 ILE E 354 29.800 -24.918 -26.225 1.00 35.25 C ANISOU 4185 CD1 ILE E 354 5197 4643 3554 -625.

11. 607 C ATOM 4186 CG2 ILE E 354 30.370 -27.816 -27.461 1.00 36.99 C ANISOU 4186 CG2 ILE E 354 5377 5012 3665 -747 157 -1184 C ATOM 4187 C ILE E 354 26.513 -27.229 -27.775 1.00 39.58 C ANISOU 4187 C ILE E 354 5544 5471 4023 -734 -358 -1077 C ATOM 4188 O ILE E 354 26.029 -26.280 -28.412 1.00 40.69 O ANISOU 4188 O ILE E 354 5712 5749 4001 -707 -510 -920 O ATOM 4189 N ARG E 355 25.880 -27.817 -26.764 1.00 38.29 N

ANISOU 4189 N ARG E 355 5277 5147 4124 -726 -345 -1150 N

ATOM 4190 CA ARG E 355 24.674 -27.225 -26.217 1.00 38.79 C

ANISOU 4190 CA ARG E 355 5231 5189 4318 -672 -479 -1049 C

ATOM 4191 CB ARG E 355 23.713 -28.293 -25.719 1.00 39.53 C

ANISOU 4191 CB ARG E 355 5192 5223 4605 -741 -490 -1232 C

ATOM 4192 CG ARG E 355 23.039 -29.024 -26.844 1.00 45.52 C

ANISOU 4192 CG ARG E 355 5905 6160 5230 -836 -612 -1430 C

ATOM 4193 CD ARG E 355 22.085 -30.055 -26.303 1.00 53.44 C

ANISOU 4193 CD ARG E 355 6770 7084 6450 -932 -613 -1609 C

ATOM 4194 NE ARG E 355 22.114 -31.290 -27.088 1.00 59.58 N

ANISOU 4194 NE ARG E 355 7564 7903 7169 -1061 -606 -1876 N

ATOM 4195 CZ ARG E 355 21.599 -32.454 -26.686 1.00 62.66 C

ANISOU 4195 CZ ARG E 355 7882 8169 7757 -1181 -561 -2064 C

ATOM 4196 NH1 ARG E 355 21.011 -32.555 -25.495 1.00 61.48 N

ANISOU 4196 NH1 ARG E 355 7637 7868 7853 -1201 -510 -1999 N

ATOM 4197 NH2 ARG E 355 21.672 -33.527 -27.477 1.00 65.58 N

ANISOU 4197 NH2 ARG E 355 8278 8563 8076 -1295 -561 -2326 N

ATOM 4198 C ARG E 355 25.064 -26.273 -25.116 1.00 36.09 C

ANISOU 4198 C ARG E 355 4905 4689 4118 -577 -408 -850 C

ATOM 4199 O ARG E 355 25.478 -26.709 -24.035 1.00 34.96 O

ANISOU 4199 O ARG E 355 4749 4377 4156 -577 -270 -877 O

ATOM 4200 N VAL E 356 24.969 -24.977 -25.411 1.00 35.53 N

ANISOU 4200 N VAL E 356 4875 4668 3958 -499 -510 -651 N

ATOM 4201 CA VAL E 356 25.331 -23.934 -24.460 1.00 32.64 C

ANISOU 4201 CA VAL E 356 4532 4149 3721 -411 -457 -475 C

ATOM 4202 CB VAL E 356 25.631 -22.604 -25.178 1.00 33.72 C

ANISOU 4202 CB VAL E 356 4781 4333 3698 -360 -549 -256 C

ATOM 4203 CG1 VAL E 356 25.785 -21.456 -24.168 1.00 31.57 C

ANISOU 4203 CG1 VAL E 356 4517 3879 3601 -265 -523 -99 C

ATOM 4204 CG2 VAL E 356 26.875 -22.756 -26.040 1.00 33.21 C

ANISOU 4204 CG2 VAL E 356 4859 4358 3403 -450 -446 -246 C

ATOM 4205 C VAL E 356 24.208 -23.765 -23.447 1.00 31.55 C

ANISOU 4205 C VAL E 356 4242 3932 3814 -346 -509 -488 C

ATOM 4206 O VAL E 356 23.059 -23.558 -23.834 1.00 32.82 O

ANISOU 4206 O VAL E 356 4300 4190 3980 -309 -675 -500 O

ATOM 4207 N HIS E 357 24.545 -23.882 -22.160 1.00 28.73 N

ANISOU 4207 N HIS E 357 3860 3421 3635 -336 -366 -497 N

ATOM 4208 CA HIS E 357 23.592 -23.583 -21.092 1.00 27.88 C

ANISOU 4208 CA HIS E 357 3613 3252 3728 -280 -380 -505 C

ATOM 4209 CB HIS E 357 23.842 -24.457 -19.864 1.00 26.86 C

ANISOU 4209 CB HIS E 357 3453 3014 3739 -344 -211 -589 C

ATOM 4210 CG HIS E 357 23.454 -25.890 -20.068 1.00 25.78 C

ANISOU 4210 CG HIS E 357 3270 2906 3619 -465 -186 -748 C

ATOM 4211 ND1 HIS E 357 22.343 -26.453 -19.475 1.00 27.87 N

ANISOU 4211 ND1 HIS E 357 3387 3180 4021 -525 -182 -843 N

ATOM 4212 CE1 HIS E 357 22.243 -27.719 -19.843 1.00 27.26 C

ANISOU 4212 CE1 HIS E 357 3312 3100 3943 -648 -160 -977 C

ATOM 4213 NE2 HIS E 357 23.247 -27.995 -20.658 1.00 28.04 N

ANISOU 4213 NE2 HIS E 357 3549 3196 3910 -650 -149 -990 N

ATOM 4214 CD2 HIS E 357 24.014 -26.867 -20.820 1.00 26.06 C

ANISOU 4214 CD2 HIS E 357 3383 2956 3561 -544 -159 -844 C

ATOM 4215 C HIS E 357 23.597 -22.112 -20.736 1.00 27.57 C

ANISOU 4215 C HIS E 357 3590 3142 3745 -155 -429 -350 C

ATOM 4216 O HIS E 357 24.660 -21.522 -20.518 1.00 26.56 O

ANISOU 4216 O HIS E 357 3583 2922 3587 -140 -349 -249 O

ATOM 4217 N GLU E 358 22.399 -21.527 -20.715 1.00 28.31 N

ANISOU 4217 N GLU E 358 3550 3275 3930 -63 -567 -348 N

ATOM 4218 CA GLU E 358 22.216 -20.116 -20.449 1.00 28.24 C

ANISOU 4218 CA GLU E 358 3543 3178 401.

80. 644 -222 C

ATOM 4219 CB GLU E 358 21.452 -19.463 -21.593 1.00 30.21 C

ANISOU 4219 CB GLU E 358 3775 3519 4186 174 -884 -133 C

ATOM 4220 CG GLU E 358 22.112 -19.703 -22.953 1.00 31.27 C

ANISOU 4220 CG GLU E 358 4073 3757 405.

94. 943 -48 C

ATOM 4221 CD GLU E 358 21.291 -19.234 -24.129 1.00 35.58 C

ANISOU 4221 CD GLU E 358 4604 4435 4480 170 -1200 41 C ATOM 4222 OE1 GLU E 358 20.044 -19.336 -24.097 1.00 36.53 O ANISOU 4222 OE1 GLU E 358 4532 4641 4708 242 -1341 -49 O ATOM 4223 OE2 GLU E 358 21.915 -18.767 -25.108 1.00 40.00 O ANISOU 4223 OE2 GLU E 358 5342 5029 4827 150 -1264 206 O ATOM 4224 C GLU E 358 21.481 -19.944 -19.121 1.00 28.03 C ANISOU 4224 C GLU E 358 3350 3095 4206 136 -577 -318 C ATOM 4225 O GLU E 358 20.399 -20.505 -18.923 1.00 28.19 O ANISOU 4225 O GLU E 358 3188 3214 4310 121 -606 -448 O ATOM 4226 N GLY E 359 22.095 -19.173 -18.223 1.00 26.47 N ANISOU 4226 N GLY E 359 3210 2755 4092 185 -480 -269 N ATOM 4227 CA GLY E 359 21.487 -18.828 -16.971 1.00 25.81 C ANISOU 4227 CA GLY E 359 2985 2630 4193 246 -409 -364 C ATOM 4228 C GLY E 359 22.386 -19.086 -15.810 1.00 23.40 C ANISOU 4228 C GLY E 359 2743 2248 3898 169 -211 -393 C ATOM 4229 O GLY E 359 23.253 -19.970 -15.866 1.00 23.25 O ANISOU 4229 O GLY E 359 2827 2236 377.

53. 119 -381 O ATOM 4230 N TYR E 360 22.143 -18.340 -14.742 1.00 23.60 N ANISOU 4230 N TYR E 360 2697 2212 4057 243 -154 -447 N ATOM 4231 CA TYR E 360 22.840 -18.486 -13.476 1.00 22.59 C ANISOU 4231 CA TYR E 360 2606 2041 3936 18.

21. 491 C ATOM 4232 CB TYR E 360 22.563 -17.303 -12.523 1.00 24.19 C ANISOU 4232 CB TYR E 360 2742 2170 4279 29.

47. 560 C ATOM 4233 CG TYR E 360 23.051 -17.586 -11.112 1.00 23.41 C ANISOU 4233 CG TYR E 360 2647 2087 4160 212 225 -639 C ATOM 4234 CD1 TYR E 360 24.414 -17.521 -10.793 1.00 22.30 C ANISOU 4234 CD1 TYR E 360 2665 1873 3936 153 290 -572 C ATOM 4235 CE1 TYR E 360 24.866 -17.828 -9.505 1.00 23.08 C ANISOU 4235 CE1 TYR E 360 2769 2011 3991 82 427 -634 C ATOM 4236 CZ TYR E 360 23.948 -18.220 -8.543 1.00 23.76 C ANISOU 4236 CZ TYR E 360 2717 2212 4098 51 519 -752 C ATOM 4237 OH TYR E 360 24.387 -18.506 -7.272 1.00 25.07 O ANISOU 4237 OH TYR E 360 2903 2436 4185 -28 647 -795 O ATOM 4238 CE2 TYR E 360 22.593 -18.299 -8.837 1.00 23.70 C ANISOU 4238 CE2 TYR E 360 2542 2282 4181 91 483 -829 C ATOM 4239 CD2 TYR E 360 22.156 -17.984 -10.118 1.00 24.20 C ANISOU 4239 CD2 TYR E 360 2586 2303 4305 179 326 -777 C ATOM 4240 C TYR E 360 22.448 -19.792 -12.804 1.00 22.00 C ANISOU 4240 C TYR E 360 2446 2074 3840 52 139 -585 C ATOM 4241 O TYR E 360 21.253 -20.113 -12.717 1.00 23.47 O ANISOU 4241 O TYR E 360 2461 2361 4097 47 124 -681 O ATOM 4242 N GLU E 361 23.457 -20.544 -12.352 1.00 20.15 N ANISOU 4242 N GLU E 361 2328 1813 3516 -52 249 -550 N ATOM 4243 CA GLU E 361 23.240 -21.781 -11.604 1.00 20.24 C ANISOU 4243 CA GLU E 361 2302 1881 3506 -182 365 -600 C ATOM 4244 CB GLU E 361 23.280 -23.001 -12.533 1.00 20.04 C ANISOU 4244 CB GLU E 361 2319 1870 3425 -274 330 -587 C ATOM 4245 CG GLU E 361 22.084 -23.147 -13.487 1.00 20.79 C ANISOU 4245 CG GLU E 361 2284 2055 3561 -270 215 -651 C ATOM 4246 CD GLU E 361 22.262 -24.295 -14.477 1.00 22.54 C ANISOU 4246 CD GLU E 361 2567 2285 3713 -366 176 -664 C ATOM 4247 OE1 GLU E 361 23.309 -24.332 -15.160 1.00 21.63 O ANISOU 4247 OE1 GLU E 361 2597 2118 3502 -350 153 -602 O ATOM 4248 OE2 GLU E 361 21.336 -25.150 -14.592 1.00 25.55 O ANISOU 4248 OE2 GLU E 361 2839 2731 4140 -464 173 -754 O ATOM 4249 C GLU E 361 24.332 -21.935 -10.561 1.00 19.23 C ANISOU 4249 C GLU E 361 2283 1704 3319 -225 479 -560 C ATOM 4250 O GLU E 361 25.489 -21.586 -10.802 1.00 18.49 O ANISOU 4250 O GLU E 361 2312 1537 3174 -195 463 -490 O ATOM 4251 N GLU E 362 23.965 -22.487 -9.413 1.00 19.76 N ANISOU 4251 N GLU E 362 2298 1827 3381 -307 593 -601 N ATOM 4252 CA GLU E 362 24.937 -22.899 -8.402 1.00 19.50 C ANISOU 4252 CA GLU E 362 2372 1771 3266 -364 684 -547 C ATOM 4253 CB GLU E 362 24.684 -22.172 -7.076 1.00 19.25 C ANISOU 4253 CB GLU E 362 2279 1811 3225 -354 772 -615 C ATOM 4254 CG GLU E 362 25.760 -22.371 -6.025 1.00 21.30 C ANISOU 4254 CG GLU E 362 2650 2069 3375 -395 835 -559 C ATOM 4255 CD GLU E 362 25.377 -21.770 -4.703 1.00 25.48 C ANISOU 4255 CD GLU E 362 3112 2708 3863 -409 932 -651 C ATOM 4256 OE1 GLU E 362 25.884 -20.702 -4.358 1.00 29.65 O ANISOU 4256 OE1 GLU E 362 3651 3221 4393 -334 920 -709 O ATOM 4257 OE2 GLU E 362 24.528 -22.338 -4.008 1.00 33.55 O ANISOU 4257 OE2 GLU E 362 4062 3839 4848 -507 1030 -680 O ATOM 4258 C GLU E 362 24.871 -24.422 -8.213 1.00 19.37 C ANISOU 4258 C GLU E 362 2397 1748 3215 -498 738 -502 C ATOM 4259 O GLU E 362 23.795 -24.978 -8.171 1.00 20.68 O ANISOU 4259 O GLU E 362 2465 1971 3423 -582 771 -549 O ATOM 4260 N PHE E 363 26.034 -25.068 -8.098 1.00 19.27 N ANISOU 4260 N PHE E 363 2522 1656 3143 -514 741 -414 N ATOM 4261 CA PHE E 363 26.136 -26.509 -7.875 1.00 20.25 C ANISOU 4261 CA PHE E 363 2717 1722 3257 -621 778 -353 C ATOM 4262 CB PHE E 363 26.740 -27.207 -9.116 1.00 19.58 C ANISOU 4262 CB PHE E 363 2705 1534 3201 -599 705 -347 C ATOM 4263 CG PHE E 363 25.919 -27.074 -10.368 1.00 19.78 C ANISOU 4263 CG PHE E 363 2651 1593 3274 -596 638 -432 C ATOM 4264 CD1 PHE E 363 24.935 -28.007 -10.676 1.00 22.26 C ANISOU 4264 CD1 PHE E 363 2909 1905 3645 -708 644 -486 C ATOM 4265 CE1 PHE E 363 24.176 -27.899 -11.843 1.00 22.61 C ANISOU 4265 CE1 PHE E 363 2868 2006 3717 -706 560 -575 C ATOM 4266 CZ PHE E 363 24.434 -26.853 -12.731 1.00 21.83 C ANISOU 4266 CZ PHE E 363 2762 1956 3576 -585 467 -582 C ATOM 4267 CE2 PHE E 363 25.409 -25.906 -12.425 1.00 21.29 C ANISOU 4267 CE2 PHE E 363 2764 1866 3461 -485 474 -512 C ATOM 4268 CD2 PHE E 363 26.145 -26.028 -11.248 1.00 21.29 C ANISOU 4268 CD2 PHE E 363 2826 1817 3445 -493 560 -452 C ATOM 4269 C PHE E 363 27.072 -26.809 -6.708 1.00 20.24 C ANISOU 4269 C PHE E 363 2818 1699 3172 -634 823 -258 C ATOM 4270 O PHE E 363 28.019 -26.078 -6.466 1.00 18.19 O ANISOU 4270 O PHE E 363 2595 1448 2868 -549 797 -245 O ATOM 4271 N THR E 364 26.798 -27.908 -6.012 1.00 21.35 N ANISOU 4271 N THR E 364 3007 1811 3294 -749 880 -184 N ATOM 4272 CA THR E 364 27.846 -28.619 -5.311 1.00 21.53 C ANISOU 4272 CA THR E 364 3165 1757 3258 -747 870 -57 C ATOM 4273 CB THR E 364 27.360 -29.262 -3.994 1.00 23.12 C ANISOU 4273 CB THR E 364 3410 2001 3374 -884 958 47 C ATOM 4274 OG1 THR E 364 26.505 -30.365 -4.288 1.00 23.16 O ANISOU 4274 OG1 THR E 364 3422 1920 3459 -1022 996 71 O ATOM 4275 CG2 THR E 364 26.661 -28.251 -3.101 1.00 21.80 C ANISOU 4275 CG2 THR E 364 3139 2030 3113 -919 1046 -24 C ATOM 4276 C THR E 364 28.359 -29.730 -6.241 1.00 21.92 C ANISOU 4276 C THR E 364 3296 1633 3398 -732 808 -30 C ATOM 4277 O THR E 364 27.586 -30.289 -7.010 1.00 21.17 O ANISOU 4277 O THR E 364 3168 1488 3387 -800 812 -88 O ATOM 4278 N MSE E 365 29.664 -30.009 -6.154 1.00 21.90 N ANISOU 4278 N MSE E 365 3384 1553 3386 -638 750 34 N ATOM 4279 CA MSE E 365 30.337 -31.060 -6.894 1.00 23.37 C ANISOU 4279 CA MSE E 365 3644 1570 3666 -594 695 41 C ATOM 4280 CB MSE E 365 31.472 -30.506 -7.757 1.00 21.74 C ANISOU 4280 CB MSE E 365 3414 1378 3470 -454 639 -36 C ATOM 4281 CG MSE E 365 31.045 -29.545 -8.842 1.00 23.13 C ANISOU 4281 CG MSE E 365 3502 1647 3639 -443 640 -154 C ATOM 4282 SE MSE E 365 32.526 -28.585 -9.625 0.90 23.40 SE ANISOU 4282 SE MSE E 365 3512 1739 3638 -313 602 -208 SE ATOM 4283 CE MSE E 365 33.771 -30.022 -9.974 1.00 18.37 C ANISOU 4283 CE MSE E 365 2937 958 3086 -233 569 -221 C ATOM 4284 C MSE E 365 30.960 -31.945 -5.849 1.00 24.00 C ANISOU 4284 C MSE E 365 3840 1550 3729 -592 674 197 C ATOM 4285 O MSE E 365 31.712 -31.448 -5.007 1.00 24.02 O ANISOU 4285 O MSE E 365 3857 1634 3635 -529 647 264 O ATOM 4286 N VAL E 366 30.647 -33.239 -5.897 1.00 24.70 N ANISOU 4286 N VAL E 366 4015 1459 3911 -665 674 257 N ATOM 4287 CA VAL E 366 31.225 -34.211 -4.985 1.00 26.44 C ANISOU 4287 CA VAL E 366 4372 1538 4136 -656 631 436 C ATOM 4288 CB VAL E 366 30.132 -34.805 -4.045 1.00 28.13 C ANISOU 4288 CB VAL E 366 4654 1731 4302 -858 710 576 C ATOM 4289 CG1 VAL E 366 30.702 -35.906 -3.156 1.00 29.65 C ANISOU 4289 CG1 VAL E 366 5023 1742 4502 -858 650 802 C ATOM 4290 CG2 VAL E 366 29.493 -33.697 -3.201 1.00 27.64 C ANISOU 4290 CG2 VAL E 366 4506 1933 4062 -936 796 572 C ATOM 4291 C VAL E 366 31.984 -35.333 -5.738 1.00 27.40 C ANISOU 4291 C VAL E 366 4567 1412 4432 -557 553 413 C ATOM 4292 O VAL E 366 31.382 -36.089 -6.501 1.00 27.59 O ANISOU 4292 O VAL E 366 4608 1292 4584 -633 575 335 O ATOM 4293 N GLY E 367 33.293 -35.428 -5.493 1.00 28.19 N ANISOU 4293 N GLY E 367 4697 1473 4542 -388 461 462 N ATOM 4294 CA GLY E 367 34.123 -36.526 -5.992 1.00 30.20 C ANISOU 4294 CA GLY E 367 5014 1486 4973 -261 380 446 C ATOM 4295 C GLY E 367 34.685 -37.405 -4.894 1.00 33.69 C ANISOU 4295 C GLY E 367 5595 1766 5439 -206 286 673 C ATOM 4296 O GLY E 367 34.376 -37.209 -3.720 1.00 34.80 O ANISOU 4296 O GLY E 367 5797 1996 5427 -292 292 858 O ATOM 4297 N LYS E 368 35.498 -38.390 -5.273 1.00 35.94 N ANISOU 4297 N LYS E 368 5932 1812 5911 -57 196 658 N ATOM 4298 CA LYS E 368 36.162 -39.264 -4.312 1.00 38.97 C ANISOU 4298 CA LYS E 368 6451 2010 6347 42 69 884 C ATOM 4299 CB LYS E 368 36.914 -40.385 -5.031 1.00 41.21 C ANISOU 4299 CB LYS E 368 6767 1990 6901 219 -19 796 C ATOM 4300 CG LYS E 368 36.054 -41.402 -5.755 1.00 44.82 C ANISOU 4300 CG LYS E 368 7315 2166 7548 97 41 717 C ATOM 4301 CD LYS E 368 36.966 -42.427 -6.402 1.00 52.13 C ANISOU 4301 CD LYS E 368 8260 2799 8749 311 -54 600 C ATOM 4302 CE LYS E 368 36.378 -43.018 -7.678 1.00 55.25 C ANISOU 4302 CE LYS E 368 8645 3030 9319 233 28 339 C ATOM 4303 NZ LYS E 368 37.081 -44.304 -8.039 1.00 58.01 N ANISOU 4303 NZ LYS E 368 9071 2998 9973 415 -68 265 N ATOM 4304 C LYS E 368 37.163 -38.513 -3.429 1.00 38.51 C ANISOU 4304 C LYS E 368 6337 2165 6130 175 -25 979 C ATOM 4305 O LYS E 368 37.330 -38.848 -2.254 1.00 40.15 O ANISOU 4305 O LYS E 368 6662 2346 6248 176 -113 1226 O ATOM 4306 N ARG E 369 37.827 -37.509 -4.010 1.00 36.39 N ANISOU 4306 N ARG E 369 5893 2111 5823 272 -10 786 N ATOM 4307 CA ARG E 369 39.003 -36.893 -3.397 1.00 36.20 C ANISOU 4307 CA ARG E 369 5782 2263 5708 423 -115 816 C ATOM 4308 CB ARG E 369 40.271 -37.288 -4.170 1.00 37.98 C ANISOU 4308 CB ARG E 369 5899 2401 6129 655 -198 665 C ATOM 4309 CG ARG E 369 40.565 -38.794 -4.243 1.00 41.98 C ANISOU 4309 CG ARG E 369 6520 2561 6871 788 -303 738 C ATOM 4310 CD ARG E 369 42.027 -39.098 -3.979 1.00 47.29 C ANISOU 4310 CD ARG E 369 7105 3211 7651 1057 -473 743 C ATOM 4311 NE ARG E 369 42.155 -39.943 -2.787 1.00 54.15 N ANISOU 4311 NE ARG E 369 8144 3905 8525 1121 -641 1046 N ATOM 4312 CZ ARG E 369 42.934 -39.702 -1.733 1.00 55.72 C ANISOU 4312 CZ ARG E 369 8323 4243 8606 1231 -801 1209 C ATOM 4313 NH1 ARG E 369 43.718 -38.625 -1.680 1.00 54.95 N ANISOU 4313 NH1 ARG E 369 8026 4461 8393 1288 -814 1079 N ATOM 4314 NH2 ARG E 369 42.930 -40.558 -0.724 1.00 58.26 N ANISOU 4314 NH2 ARG E 369 8832 4383 8920 1274 -956 1510 N ATOM 4315 C ARG E 369 38.934 -35.380 -3.308 1.00 33.75 C ANISOU 4315 C ARG E 369 5345 2273 5207 348 -39 717 C ATOM 4316 O ARG E 369 39.914 -34.725 -2.945 1.00 34.16 O ANISOU 4316 O ARG E 369 5295 2491 5191 450 -111 692 O ATOM 4317 N ALA E 370 37.792 -34.814 -3.675 1.00 31.33 N ANISOU 4317 N ALA E 370 5030 2041 4833 176 99 647 N ATOM 4318 CA ALA E 370 37.559 -33.400 -3.527 1.00 28.93 C ANISOU 4318 CA ALA E 370 4628 1995 4370 100 169 566 C ATOM 4319 CB ALA E 370 38.363 -32.620 -4.535 1.00 27.23 C ANISOU 4319 CB ALA E 370 4264 1875 4207 190 183 368 C ATOM 4320 C ALA E 370 36.067 -33.095 -3.648 1.00 28.11 C ANISOU 4320 C ALA E 370 4547 1924 4208 -87 299 547 C ATOM 4321 O ALA E 370 35.301 -33.902 -4.202 1.00 28.06 O ANISOU 4321 O ALA E 370 4597 1757 4307 -159 342 541 O ATOM 4322 N THR E 371 35.662 -31.950 -3.090 1.00 27.19 N ANISOU 4322 N THR E 371 4377 2016 3936 -165 354 524 N ATOM 4323 CA THR E 371 34.304 -31.425 -3.247 1.00 26.56 C ANISOU 4323 CA THR E 371 4270 2009 3814 -313 474 464 C ATOM 4324 CB THR E 371 33.385 -31.679 -2.005 1.00 28.20 C ANISOU 4324 CB THR E 371 4554 2275 3886 -460 531 605 C ATOM 4325 OG1 THR E 371 33.794 -30.847 -0.909 1.00 29.59 O ANISOU 4325 OG1 THR E 371 4714 2648 3883 -451 514 632 O ATOM 4326 CG2 THR E 371 33.393 -33.154 -1.572 1.00 28.40 C ANISOU 4326 CG2 THR E 371 4730 2103 3955 -493 486 799 C ATOM 4327 C THR E 371 34.395 -29.935 -3.534 1.00 25.42 C ANISOU 4327 C THR E 371 4005 2038 3615 -293 508 318 C ATOM 4328 O THR E 371 35.432 -29.303 -3.270 1.00 26.43 O ANISOU 4328 O THR E 371 4090 2253 3699 -209 452 292 O ATOM 4329 N ALA E 372 33.332 -29.363 -4.091 1.00 23.65 N ANISOU 4329 N ALA E 372 3723 1856 3408 -370 590 222 N ATOM 4330 CA ALA E 372 33.374 -27.962 -4.454 1.00 21.68 C ANISOU 4330 CA ALA E 372 3378 1723 3137 -344 611 98 C ATOM 4331 CB ALA E 372 34.062 -27.763 -5.828 1.00 20.08 C ANISOU 4331 CB ALA E 372 3135 1466 3029 -263 579 10 C ATOM 4332 C ALA E 372 32.005 -27.314 -4.448 1.00 20.75 C ANISOU 4332 C ALA E 372 3202 1678 3005 -430 691 32 C ATOM 4333 O ALA E 372 30.976 -28.000 -4.439 1.00 20.60 O ANISOU 4333 O ALA E 372 3192 1627 3010 -519 740 58 O ATOM 4334 N ILE E 373 32.007 -25.988 -4.420 1.00 19.68 N ANISOU 4334 N ILE E 373 2997 1635 2845 -402 704 -60 N ATOM 4335 CA ILE E 373 30.801 -25.212 -4.699 1.00 20.41 C ANISOU 4335 CA ILE E 373 3008 1776 2971 -434 756 -152 C ATOM 4336 CB ILE E 373 30.356 -24.310 -3.515 1.00 21.75 C ANISOU 4336 CB ILE E 373 3130 2078 3058 -463 816 -213 C ATOM 4337 CG1 ILE E 373 30.315 -25.102 -2.203 1.00 22.01 C ANISOU 4337 CG1 ILE E 373 3221 2184 2956 -546 858 -120 C ATOM 4338 CD1 ILE E 373 29.912 -24.273 -0.985 1.00 23.87 C ANISOU 4338 CD1 ILE E 373 3410 2587 3072 -587 931 -202 C ATOM 4339 CG2 ILE E 373 28.992 -23.701 -3.819 1.00 22.34 C ANISOU 4339 CG2 ILE E 373 3098 2190 3199 -479 868 -317 C ATOM 4340 C ILE E 373 31.126 -24.332 -5.891 1.00 19.23 C ANISOU 4340 C ILE E 373 2823 1587 2896 -361 711 -221 C ATOM 4341 O ILE E 373 32.156 -23.665 -5.899 1.00 18.51 O ANISOU 4341 O ILE E 373 2742 1500 2792 -313 680 -234 O ATOM 4342 N LEU E 374 30.252 -24.362 -6.898 1.00 18.79 N ANISOU 4342 N LEU E 374 2728 1502 2910 -368 705 -257 N ATOM 4343 CA LEU E 374 30.467 -23.673 -8.178 1.00 17.10 C ANISOU 4343 CA LEU E 374 2503 1253 2742 -312 653 -288 C ATOM 4344 CB LEU E 374 30.623 -24.697 -9.314 1.00 17.63 C ANISOU 4344 CB LEU E 374 2605 1264 2828 -322 623 -275 C ATOM 4345 CG LEU E 374 30.560 -24.218 -10.764 1.00 17.47 C ANISOU 4345 CG LEU E 374 2579 1243 2816 -294 572 -302 C ATOM 4346 CD1 LEU E 374 31.820 -23.383 -11.076 1.00 17.18 C ANISOU 4346 CD1 LEU E 374 2575 1203 2747 -255 564 -283 C ATOM 4347 CD2 LEU E 374 30.469 -25.360 -11.696 1.00 17.08 C ANISOU 4347 CD2 LEU E 374 2553 1165 2772 -323 556 -327 C ATOM 4348 C LEU E 374 29.286 -22.786 -8.498 1.00 16.92 C ANISOU 4348 C LEU E 374 2401 1258 2770 -295 642 -348 C ATOM 4349 O LEU E 374 28.126 -23.249 -8.481 1.00 15.98 O ANISOU 4349 O LEU E 374 2218 1172 2681 -335 659 -377 O ATOM 4350 N ARG E 375 29.570 -21.498 -8.726 1.00 16.55 N ANISOU 4350 N ARG E 375 2349 1192 2748 -236 611 -368 N ATOM 4351 CA ARG E 375 28.615 -20.620 -9.352 1.00 17.49 C ANISOU 4351 CA ARG E 375 2408 1298 2938 -184 562 -403 C ATOM 4352 CB ARG E 375 28.483 -19.295 -8.633 1.00 18.68 C ANISOU 4352 CB ARG E 375 2524 1428 3145 -130 572 -466 C ATOM 4353 CG ARG E 375 27.717 -19.389 -7.371 1.00 20.56 C ANISOU 4353 CG ARG E 375 2678 1751 3384 -149 650 -557 C ATOM 4354 CD ARG E 375 27.873 -18.091 -6.582 1.00 21.88 C ANISOU 4354 CD ARG E 375 2826 1893 3596 -98 670 -652 C ATOM 4355 NE ARG E 375 27.046 -18.192 -5.379 1.00 25.86 N ANISOU 4355 NE ARG E 375 3235 2515 4078 -123 763 -765 N ATOM 4356 CZ ARG E 375 27.146 -17.421 -4.310 1.00 26.86 C ANISOU 4356 CZ ARG E 375 3334 2677 4193 -112 819 -885 C ATOM 4357 NH1 ARG E 375 28.046 -16.437 -4.266 1.00 25.55 N ANISOU 4357 NH1 ARG E 375 3231 2415 4060 -78 782 -912 N ATOM 4358 NH2 ARG E 375 26.320 -17.641 -3.296 1.00 29.10 N ANISOU 4358 NH2 ARG E 375 3524 3103 4428 -151 921 -990 N ATOM 4359 C ARG E 375 29.014 -20.386 -10.800 1.00 18.25 C ANISOU 4359 C ARG E 375 2561 1348 3024 -160 485 -343 C ATOM 4360 O ARG E 375 30.185 -20.109 -11.131 1.00 17.38 O ANISOU 4360 O ARG E 375 2525 1203 2875 -168 486 -298 O ATOM 4361 N LYS E 376 28.012 -20.433 -11.660 1.00 18.54 N ANISOU 4361 N LYS E 376 2552 1405 3088 -138 418 -348 N ATOM 4362 CA LYS E 376 28.255 -20.335 -13.071 1.00 19.40 C ANISOU 4362 CA LYS E 376 2719 1506 3147 -130 341 -288 C ATOM 4363 CB LYS E 376 28.315 -21.771 -13.583 1.00 20.73 C ANISOU 4363 CB LYS E 376 2900 1723 3255 -198 357 -310 C ATOM 4364 CG LYS E 376 28.136 -21.939 -15.015 1.00 24.60 C ANISOU 4364 CG LYS E 376 3416 2255 3675 -204 277 -295 C ATOM 4365 CD LYS E 376 27.437 -23.258 -15.295 1.00 25.85 C ANISOU 4365 CD LYS E 376 3527 2461 3833 -265 272 -374 C ATOM 4366 CE LYS E 376 27.641 -23.566 -16.743 1.00 24.77 C ANISOU 4366 CE LYS E 376 3442 2383 3587 -287 210 -382 C ATOM 4367 NZ LYS E 376 26.874 -22.594 -17.523 1.00 26.75 N ANISOU 4367 NZ LYS E 376 3667 2688 3807 -233.

84. 331 N ATOM 4368 C LYS E 376 27.119 -19.526 -13.719 1.00 19.69 C ANISOU 4368 C LYS E 376 2697 1543 3240 -55 230 -279 C ATOM 4369 O LYS E 376 26.022 -19.438 -13.178 1.00 19.19 O ANISOU 4369 O LYS E 376 2517 1510 3263 -17 221 -351 O ATOM 4370 N ALA E 377 27.402 -18.913 -14.861 1.00 19.87 N ANISOU 4370 N ALA E 377 2797 1542 3209 -31 144 -188 N ATOM 4371 CA ALA E 377 26.369 -18.220 -15.644 1.00 21.63 C ANISOU 4371 CA ALA E 377 2981 1768 3469 54 0 -149 C ATOM 4372 CB ALA E 377 26.452 -16.693 -15.458 1.00 21.14 C ANISOU 4372 CB ALA E 377 2959 1567 3505 144 -50 -82 C ATOM 4373 C ALA E 377 26.594 -18.616 -17.102 1.00 21.95 C ANISOU 4373 C ALA E 377 3102 1884 335.

9. 75 -74 C ATOM 4374 O ALA E 377 27.330 -19.549 -17.351 1.00 21.69 O ANISOU 4374 O ALA E 377 3116 1904 3222 -80 1 -102 O ATOM 4375 N THR E 378 25.972 -17.923 -18.050 1.00 23.90 N ANISOU 4375 N THR E 378 3362 2140 3578.

76. 228 13 N ATOM 4376 CA THR E 378 26.139 -18.227 -19.483 1.00 25.60 C ANISOU 4376 CA THR E 378 3662 2460 360.

26. 310 87 C ATOM 4377 CB THR E 378 25.299 -17.275 -20.380 1.00 27.85 C ANISOU 4377 CB THR E 378 3960 2747 3875 127 -515 214 C ATOM 4378 OG1 THR E 378 23.947 -17.261 -19.926 1.00 29.57 O ANISOU 4378 OG1 THR E 378 4001 2984 4250 234 -608 120 O ATOM 4379 CG2 THR E 378 25.304 -17.743 -21.851 1.00 30.08 C ANISOU 4379 CG2 THR E 378 4315 3193 392.

64. 612 270 C ATOM 4380 C THR E 378 27.615 -18.190 -19.933 1.00 25.01 C ANISOU 4380 C THR E 378 3737 2377 3386 -74 -208 164 C ATOM 4381 O THR E 378 28.215 -17.115 -20.060 1.00 25.04 O ANISOU 4381 O THR E 378 3843 2284 3387 -70 -212 297 O ATOM 4382 N ARG E 379 28.184 -19.373 -20.172 1.00 24.99 N ANISOU 4382 N ARG E 379 3740 2472 3282 -166 -114 69 N ATOM 4383 CA ARG E 379 29.589 -19.500 -20.611 1.00 25.62 C ANISOU 4383 CA ARG E 379 3921 2580 3232 -258 -1 97 C ATOM 4384 CB ARG E 379 29.750 -19.126 -22.102 1.00 27.18 C ANISOU 4384 CB ARG E 379 4227 2889 3212 -308 -73 210 C ATOM 4385 CG ARG E 379 28.814 -19.879 -23.053 1.00 28.80 C ANISOU 4385 CG ARG E 379 4399 3250 3295 -310 -189 143 C ATOM 4386 CD ARG E 379 29.241 -19.684 -24.521 1.00 29.35 C ANISOU 4386 CD ARG E 379 4591 3475 3087 -391 -225 235 C ATOM 4387 NE ARG E 379 30.539 -20.308 -24.733 1.00 29.26 N ANISOU 4387 NE ARG E 379 4615 3531 2972 -495 -44 147 N ATOM 4388 CZ ARG E 379 31.290 -20.180 -25.826 1.00 30.78 C ANISOU 4388 CZ ARG E 379 4907 3869 2920 -596 5 198 C ATOM 4389 NH1 ARG E 379 30.879 -19.451 -26.857 1.00 32.74 N ANISOU 4389 NH1 ARG E 379 5258 4210 2972 -620 -124 368 N ATOM 4390 NH2 ARG E 379 32.460 -20.789 -25.883 1.00 28.70 N ANISOU 4390 NH2 ARG E 379 4634 3667 2604 -672 184 78 N ATOM 4391 C ARG E 379 30.531 -18.661 -19.737 1.00 25.30 C ANISOU 4391 C ARG E 379 3915 2410 3286 -262 92 154 C ATOM 4392 O ARG E 379 31.356 -17.912 -20.253 1.00 26.75 O ANISOU 4392 O ARG E 379 4194 2579 3389 -319 119 264 O ATOM 4393 N ARG E 380 30.394 -18.803 -18.417 1.00 25.10 N ANISOU 4393 N ARG E 380 3810 2304 3421 -220 143 73 N ATOM 4394 CA ARG E 380 31.158 -18.022 -17.438 1.00 25.31 C ANISOU 4394 CA ARG E 380 3851 2220 3547 -222 216 92 C ATOM 4395 CB ARG E 380 30.500 -16.655 -17.212 1.00 26.33 C ANISOU 4395 CB ARG E 380 3995 2220 3788 -147 126 171 C ATOM 4396 CG ARG E 380 31.262 -15.682 -16.289 1.00 27.56 C ANISOU 4396 CG ARG E 380 4176 2243 4052 -160 190 176 C ATOM 4397 CD ARG E 380 30.391 -14.433 -16.058 1.00 30.89 C ANISOU 4397 CD ARG E 380 4602 2511 4622 -58 88 218 C ATOM 4398 NE ARG E 380 30.622 -13.828 -14.744 1.00 38.11 N ANISOU 4398 NE ARG E 380 5478 3322 5681 -38 149 120 N ATOM 4399 CZ ARG E 380 29.754 -13.045 -14.114 1.00 42.71 C ANISOU 4399 CZ ARG E 380 6009 3793 6425 71 96 61 C ATOM 4400 NH1 ARG E 380 28.579 -12.763 -14.675 1.00 45.06 N ANISOU 4400 NH1 ARG E 380 6275 4064 6780 186 -32 102 N ATOM 4401 NH2 ARG E 380 30.059 -12.552 -12.914 1.00 44.78 N ANISOU 4401 NH2 ARG E 380 6238 3985 6791 72 166 -57 N ATOM 4402 C ARG E 380 31.203 -18.783 -16.134 1.00 23.46 C ANISOU 4402 C ARG E 380 3532 1980 3404 -208 293 -29 C ATOM 4403 O ARG E 380 30.167 -19.189 -15.617 1.00 24.09 O ANISOU 4403 O ARG E 380 3534 2067 3551 -163 264 -91 O ATOM 4404 N LEU E 381 32.405 -19.005 -15.619 1.00 22.65 N ANISOU 4404 N LEU E 381 3438 1877 3293 -254 389 -57 N ATOM 4405 CA LEU E 381 32.583 -19.406 -14.222 1.00 21.63 C ANISOU 4405 CA LEU E 381 3250 1728 3240 -238 446 -133 C ATOM 4406 CB LEU E 381 33.941 -20.107 -14.030 1.00 21.33 C ANISOU 4406 CB LEU E 381 3212 1732 3162 -278 523 -167 C ATOM 4407 CG LEU E 381 34.244 -20.753 -12.662 1.00 19.23 C ANISOU 4407 CG LEU E 381 2900 1465 2942 -259 560 -221 C ATOM 4408 CD1 LEU E 381 35.081 -21.997 -12.834 1.00 13.40 C ANISOU 4408 CD1 LEU E 381 2152 765 2174 -259 593 -258 C ATOM 4409 CD2 LEU E 381 34.922 -19.699 -11.796 1.00 17.93 C ANISOU 4409 CD2 LEU E 381 2726 1273 2813 -272 577 -225 C ATOM 4410 C LEU E 381 32.513 -18.135 -13.379 1.00 21.99 C ANISOU 4410 C LEU E 381 3292 1685 3378 -213 439 -126 C ATOM 4411 O LEU E 381 33.301 -17.199 -13.572 1.00 23.59 O ANISOU 4411 O LEU E 381 3544 1833 3586 -250 450 -79 O ATOM 4412 N VAL E 382 31.546 -18.064 -12.477 1.00 21.86 N ANISOU 4412 N VAL E 382 3214 1654 3439 -161 427 -184 N ATOM 4413 CA VAL E 382 31.417 -16.882 -11.602 1.00 21.55 C ANISOU 4413 CA VAL E 382 3160 1532 3496 -127 428 -223 C ATOM 4414 CB VAL E 382 29.957 -16.691 -11.098 1.00 21.88 C ANISOU 4414 CB VAL E 382 3114 1573 3625 -48 398 -294 C ATOM 4415 CG1 VAL E 382 29.859 -15.541 -10.076 1.00 22.19 C ANISOU 4415 CG1 VAL E 382 3128 1534 3770 -6 417 -382 C ATOM 4416 CG2 VAL E 382 29.020 -16.449 -12.269 1.00 20.93 C ANISOU 4416 CG2 VAL E 382 2990 1431 3530 11 293 -231 C ATOM 4417 C VAL E 382 32.403 -17.045 -10.441 1.00 20.98 C ANISOU 4417 C VAL E 382 3076 1491 3404 -172 502 -285 C ATOM 4418 O VAL E 382 33.214 -16.165 -10.189 1.00 21.61 O ANISOU 4418 O VAL E 382 3184 1514 3514 -203 515 -294 O ATOM 4419 N GLN E 383 32.352 -18.188 -9.762 1.00 20.35 N ANISOU 4419 N GLN E 383 2959 1500 3272 -184 541 -319 N ATOM 4420 CA GLN E 383 33.239 -18.459 -8.653 1.00 20.51 C ANISOU 4420 CA GLN E 383 2970 1571 3251 -214 585 -358 C ATOM 4421 CB GLN E 383 32.825 -17.601 -7.432 1.00 22.63 C ANISOU 4421 CB GLN E 383 3202 1840 3555 -201 605 -454 C ATOM 4422 CG GLN E 383 33.753 -17.779 -6.252 1.00 28.07 C ANISOU 4422 CG GLN E 383 3885 2608 4173 -239 631 -498 C ATOM 4423 CD GLN E 383 33.698 -16.625 -5.265 1.00 36.66 C ANISOU 4423 CD GLN E 383 4948 3689 5291 -243 647 -622 C ATOM 4424 OE1 GLN E 383 32.636 -15.998 -5.049 1.00 36.66 O ANISOU 4424 OE1 GLN E 383 4916 3654 5358 -202 662 -698 O ATOM 4425 NE2 GLN E 383 34.860 -16.332 -4.649 1.00 38.02 N ANISOU 4425 NE2 GLN E 383 5121 3901 5423 -289 640 -665 N ATOM 4426 C GLN E 383 33.243 -19.938 -8.326 1.00 19.34 C ANISOU 4426 C GLN E 383 2817 1492 3040 -225 604 -337 C ATOM 4427 O GLN E 383 32.239 -20.609 -8.509 1.00 18.92 O ANISOU 4427 O GLN E 383 2748 1449 2993 -222 605 -329 O ATOM 4428 N LEU E 384 34.387 -20.445 -7.868 1.00 18.66 N ANISOU 4428 N LEU E 384 2739 1443 2907 -238 610 -326 N ATOM 4429 CA LEU E 384 34.544 -21.825 -7.460 1.00 18.10 C ANISOU 4429 CA LEU E 384 2681 1403 2795 -235 612 -288 C ATOM 4430 CB LEU E 384 35.331 -22.585 -8.546 1.00 18.49 C ANISOU 4430 CB LEU E 384 2743 1425 2855 -217 599 -264 C ATOM 4431 CG LEU E 384 35.671 -24.077 -8.334 1.00 18.11 C ANISOU 4431 CG LEU E 384 2716 1358 2806 -190 586 -231 C ATOM 4432 CD1 LEU E 384 34.428 -24.981 -8.395 1.00 15.62 C ANISOU 4432 CD1 LEU E 384 2432 995 2509 -217 597 -207 C ATOM 4433 CD2 LEU E 384 36.728 -24.517 -9.342 1.00 17.92 C ANISOU 4433 CD2 LEU E 384 2677 1325 2807 -156 583 -260 C ATOM 4434 C LEU E 384 35.349 -21.856 -6.147 1.00 19.39 C ANISOU 4434 C LEU E 384 2837 1632 2899 -236 602 -293 C ATOM 4435 O LEU E 384 36.373 -21.166 -6.044 1.00 19.75 O ANISOU 4435 O LEU E 384 2857 1702 2944 -238 586 -328 O ATOM 4436 N ILE E 385 34.898 -22.664 -5.175 1.00 19.03 N ANISOU 4436 N ILE E 385 2812 1624 2793 -249 609 -252 N ATOM 4437 CA ILE E 385 35.659 -22.991 -3.966 1.00 19.96 C ANISOU 4437 CA ILE E 385 2941 1820 2821 -245 576 -221 C ATOM 4438 CB ILE E 385 34.993 -22.480 -2.627 1.00 21.28 C ANISOU 4438 CB ILE E 385 3107 2094 2884 -296 612 -260 C ATOM 4439 CG1 ILE E 385 34.558 -21.029 -2.788 1.00 21.71 C ANISOU 4439 CG1 ILE E 385 3111 2146 2993 -305 650 -390 C ATOM 4440 CD1 ILE E 385 33.762 -20.478 -1.643 1.00 22.98 C ANISOU 4440 CD1 ILE E 385 3249 2408 3075 -344 707 -479 C ATOM 4441 CG2 ILE E 385 36.012 -22.510 -1.462 1.00 21.32 C ANISOU 4441 CG2 ILE E 385 3118 2212 2770 -293 553 -247 C ATOM 4442 C ILE E 385 35.839 -24.504 -3.882 1.00 20.24 C ANISOU 4442 C ILE E 385 3032 1811 2849 -222 542 -109 C ATOM 4443 O ILE E 385 34.856 -25.249 -3.881 1.00 19.69 O ANISOU 4443 O ILE E 385 3003 1695 2782 -261 578 -57 O ATOM 4444 N VAL E 386 37.097 -24.943 -3.810 1.00 19.46 N ANISOU 4444 N VAL E 386 2924 1714 2754 -158 472 -79 N ATOM 4445 CA VAL E 386 37.410 -26.350 -3.752 1.00 20.14 C ANISOU 4445 CA VAL E 386 3063 1721 2866 -106 420 23 C ATOM 4446 CB VAL E 386 38.383 -26.761 -4.859 1.00 20.24 C ANISOU 4446 CB VAL E 386 3030 1666 2993 -20 390 -23 C ATOM 4447 CG1 VAL E 386 38.441 -28.280 -4.958 1.00 19.96 C ANISOU 4447 CG1 VAL E 386 3061 1495 3030 41 346 60 C ATOM 4448 CG2 VAL E 386 37.960 -26.147 -6.192 1.00 19.11 C ANISOU 4448 CG2 VAL E 386 2855 1498 2906 -57 463 -116 C ATOM 4449 C VAL E 386 37.999 -26.803 -2.420 1.00 21.41 C ANISOU 4449 C VAL E 386 3261 1950 2925 -78 336 123 C ATOM 4450 O VAL E 386 38.857 -26.159 -1.871 1.00 19.90 O ANISOU 4450 O VAL E 386 3012 1873 2674 -54 282 81 O ATOM 4451 N SER E 387 37.500 -27.932 -1.919 1.00 23.78 N ANISOU 4451 N SER E 387 3661 2176 3199 -93 320 261 N ATOM 4452 CA SER E 387 38.069 -28.605 -0.755 1.00 26.40 C ANISOU 4452 CA SER E 387 4058 2542 3430 -55 216 407 C ATOM 4453 CB SER E 387 36.995 -28.748 0.300 1.00 26.98 C ANISOU 4453 CB SER E 387 4226 2682 3345 -183 274 511 C ATOM 4454 OG SER E 387 37.539 -29.206 1.517 1.00 32.13 O ANISOU 4454 OG SER E 387 4952 3411 3846 -163 169 663 O ATOM 4455 C SER E 387 38.555 -29.968 -1.228 1.00 27.98 C ANISOU 4455 C SER E 387 4311 2549 3769 49 138 502 C ATOM 4456 O SER E 387 37.824 -30.693 -1.905 1.00 28.28 O ANISOU 4456 O SER E 387 4407 2428 3912 14 195 518 O ATOM 4457 N GLY E 388 39.787 -30.324 -0.904 1.00 30.49 N ANISOU 4457 N GLY E 388 4601 2877 4108 182 2 545 N ATOM 4458 CA GLY E 388 40.414 -31.510 -1.506 1.00 31.87 C ANISOU 4458 CA GLY E 388 4792 2855 4464 322 -77 582 C ATOM 4459 C GLY E 388 41.481 -32.119 -0.645 1.00 35.20 C ANISOU 4459 C GLY E 388 5224 3281 4870 465 -259 711 C ATOM 4460 O GLY E 388 42.053 -31.431 0.193 1.00 35.40 O ANISOU 4460 O GLY E 388 5192 3507 4752 473 -333 715 O ATOM 4461 N LYS E 389 41.744 -33.416 -0.854 1.00 37.79 N ANISOU 4461 N LYS E 389 5625 3381 5354 584 -343 808 N ATOM 4462 CA LYS E 389 42.695 -34.177 -0.038 1.00 41.58 C ANISOU 4462 CA LYS E 389 6134 3817 5846 751 -547 967 C ATOM 4463 CB LYS E 389 42.453 -35.683 -0.179 1.00 43.32 C ANISOU 4463 CB LYS E 389 6511 3710 6238 824 -607 1121 C ATOM 4464 CG LYS E 389 41.149 -36.173 0.475 1.00 45.67 C ANISOU 4464 CG LYS E 389 7029 3907 6418 632 -541 1336 C ATOM 4465 CD LYS E 389 40.990 -37.698 0.334 1.00 48.65 C ANISOU 4465 CD LYS E 389 7573 3918 6995 695 -610 1495 C ATOM 4466 CE LYS E 389 39.920 -38.253 1.282 1.00 53.15 C ANISOU 4466 CE LYS E 389 8371 4404 7418 499 -579 1774 C ATOM 4467 NZ LYS E 389 39.307 -39.499 0.737 1.00 55.21 N ANISOU 4467 NZ LYS E 389 8779 4293 7904 458 -545 1839 N ATOM 4468 C LYS E 389 44.154 -33.830 -0.362 1.00 41.93 C ANISOU 4468 C LYS E 389 5968 3976 5988 934 -650 813 C ATOM 4469 O LYS E 389 45.009 -33.920 0.510 1.00 43.82 O ANISOU 4469 O LYS E 389 6171 4312 6166 1049 -828 906 O ATOM 4470 N ASP E 390 44.426 -33.440 -1.615 1.00 40.64 N ANISOU 4470 N ASP E 390 5659 3817 5965 951 -538 578 N ATOM 4471 CA ASP E 390 45.777 -33.057 -2.081 1.00 40.81 C ANISOU 4471 CA ASP E 390 5452 3968 6088 1091 -589 396 C ATOM 4472 CB ASP E 390 46.690 -34.296 -2.287 1.00 43.89 C ANISOU 4472 CB ASP E 390 5794 4180 6703 1343 -735 406 C ATOM 4473 CG ASP E 390 46.218 -35.219 -3.405 1.00 44.30 C ANISOU 4473 CG ASP E 390 5913 3965 6955 1376 -637 329 C ATOM 4474 OD1 ASP E 390 45.353 -34.826 -4.203 1.00 44.98 O ANISOU 4474 OD1 ASP E 390 6038 4044 7009 1213 -458 233 O ATOM 4475 OD2 ASP E 390 46.724 -36.355 -3.504 1.00 48.47 O ANISOU 4475 OD2 ASP E 390 6450 4282 7682 1574 -751 352 O ATOM 4476 C ASP E 390 45.746 -32.154 -3.336 1.00 38.51 C ANISOU 4476 C ASP E 390 5031 3767 5836 995 -404 157 C ATOM 4477 O ASP E 390 44.671 -31.829 -3.839 1.00 36.33 O ANISOU 4477 O ASP E 390 4845 3447 5510 841 -259 138 O ATOM 4478 N GLU E 391 46.925 -31.763 -3.828 1.00 38.93 N ANISOU 4478 N GLU E 391 4869 3952 5972 1081 -414 -16 N ATOM 4479 CA GLU E 391 47.081 -30.789 -4.922 1.00 37.97 C ANISOU 4479 CA GLU E 391 4618 3953 5855 972 -246 -219 C ATOM 4480 CB GLU E 391 48.560 -30.441 -5.133 1.00 38.98 C ANISOU 4480 CB GLU E 391 4490 4258 6064 1066 -286 -380 C ATOM 4481 CG GLU E 391 48.856 -28.960 -4.994 1.00 40.24 C ANISOU 4481 CG GLU E 391 4543 4643 6104 900 -222 -461 C ATOM 4482 CD GLU E 391 50.336 -28.644 -4.975 1.00 43.40 C ANISOU 4482 CD GLU E 391 4675 5236 6579 973 -281 -608 C ATOM 4483 OE1 GLU E 391 50.699 -27.575 -4.425 1.00 48.91 O ANISOU 4483 OE1 GLU E 391 5289 6112 7182 857 -298 -644 O ATOM 4484 OE2 GLU E 391 51.139 -29.445 -5.512 1.00 49.31 O ANISOU 4484 OE2 GLU E 391 5283 5963 7491 1142 -308 -707 O ATOM 4485 C GLU E 391 46.489 -31.257 -6.243 1.00 36.17 C ANISOU 4485 C GLU E 391 4442 3579 5722 947 -104 -312 C ATOM 4486 O GLU E 391 45.845 -30.480 -6.927 1.00 34.25 O ANISOU 4486 O GLU E 391 4226 3383 5403 79.

37. 371 O ATOM 4487 N GLN E 392 46.733 -32.515 -6.596 1.00 36.79 N ANISOU 4487 N GLN E 392 4532 3478 5968 1108 -154 -333 N ATOM 4488 CA GLN E 392 46.180 -33.135 -7.801 1.00 36.36 C ANISOU 4488 CA GLN E 392 4533 3272 6008 1095 -38 -442 C ATOM 4489 CB GLN E 392 46.833 -34.495 -8.032 1.00 39.07 C ANISOU 4489 CB GLN E 392 4841 3428 6575 1320 -124 -506 C ATOM 4490 CG GLN E 392 46.093 -35.431 -8.959 1.00 42.17 C ANISOU 4490 CG GLN E 392 5347 3596 7078 1314 -46 -586 C ATOM 4491 CD GLN E 392 46.480 -36.877 -8.682 1.00 51.76 C ANISOU 4491 CD GLN E 392 6607 4534 8524 1534 -183 -558 C ATOM 4492 OE1 GLN E 392 46.212 -37.410 -7.595 1.00 55.83 O ANISOU 4492 OE1 GLN E 392 7265 4895 9053 1576 -325 -322 O ATOM 4493 NE2 GLN E 392 47.145 -37.513 -9.647 1.00 54.63 N ANISOU 4493 NE2 GLN E 392 6850 4836 9072 1680 -143 -798 N ATOM 4494 C GLN E 392 44.645 -33.273 -7.800 1.00 33.83 C ANISOU 4494 C GLN E 392 4427 2818 5610 94.

22. 326 C ATOM 4495 O GLN E 392 44.020 -33.044 -8.836 1.00 31.93 O ANISOU 4495 O GLN E 392 4205 2580 5345 834 152 -432 O ATOM 4496 N SER E 393 44.058 -33.650 -6.657 1.00 32.93 N ANISOU 4496 N SER E 393 4460 2605 5446 923 -72 -113 N ATOM 4497 CA SER E 393 42.611 -33.725 -6.519 1.00 31.18 C ANISOU 4497 CA SER E 393 4411 2291 5146 759 -8 -5 C ATOM 4498 CB SER E 393 42.242 -34.366 -5.185 1.00 33.05 C ANISOU 4498 CB SER E 393 4797 2419 5340 763 -120 238 C ATOM 4499 OG SER E 393 42.910 -35.606 -5.020 1.00 36.61 O ANISOU 4499 OG SER E 393 5282 2665 5964 946 -249 295 O ATOM 4500 C SER E 393 41.941 -32.337 -6.624 1.00 28.79 C ANISOU 4500 C SER E 393 4086 2181 4671 581 102 -36 C ATOM 4501 O SER E 393 40.854 -32.192 -7.202 1.00 27.10 O ANISOU 4501 O SER E 393 3935 1933 4428 456 198 -62 O ATOM 4502 N ILE E 394 42.586 -31.323 -6.062 1.00 27.47 N ANISOU 4502 N ILE E 394 3824 2208 4405 57.

76. 41 N ATOM 4503 CA ILE E 394 42.091 -29.953 -6.192 1.00 26.15 C ANISOU 4503 CA ILE E 394 3629 2193 4112 427 170 -88 C ATOM 4504 CB ILE E 394 42.826 -28.959 -5.223 1.00 26.34 C ANISOU 4504 CB ILE E 394 3570 2404 4034 417 111 -78 C ATOM 4505 CG1 ILE E 394 42.490 -29.298 -3.766 1.00 28.07 C ANISOU 4505 CG1 ILE E 394 3891 2627 4148 416 14 91 C ATOM 4506 CD1 ILE E 394 43.465 -28.723 -2.752 1.00 28.88 C ANISOU 4506 CD1 ILE E 394 3905 2906 4162 452 -94 95 C ATOM 4507 CG2 ILE E 394 42.405 -27.519 -5.487 1.00 24.76 C ANISOU 4507 CG2 ILE E 394 3340 2317 3749 276 210 -152 C ATOM 4508 C ILE E 394 42.142 -29.511 -7.661 1.00 24.62 C ANISOU 4508 C ILE E 394 3365 2030 3959 387 283 -247 C ATOM 4509 O ILE E 394 41.175 -28.957 -8.182 1.00 22.84 O ANISOU 4509 O ILE E 394 3189 1810 3678 272 366 -261 O ATOM 4510 N ALA E 395 43.257 -29.804 -8.328 1.00 25.55 N ANISOU 4510 N ALA E 395 3364 2176 4169 487 282 -366 N ATOM 4511 CA ALA E 395 43.459 -29.462 -9.732 1.00 25.07 C ANISOU 4511 CA ALA E 395 3232 2174 4119 445 397 -519 C ATOM 4512 CB ALA E 395 44.872 -29.811 -10.162 1.00 27.09 C ANISOU 4512 CB ALA E 395 3321 2497 4473 567 394 -657 C ATOM 4513 C ALA E 395 42.439 -30.156 -10.642 1.00 25.59 C ANISOU 4513 C ALA E 395 3403 2112 4209 408 454 -551 C ATOM 4514 O ALA E 395 41.894 -29.517 -11.549 1.00 23.95 O ANISOU 4514 O ALA E 395 3210 1966 3923 300 540 -600 O ATOM 4515 N GLU E 396 42.193 -31.454 -10.389 1.00 27.00 N ANISOU 4515 N GLU E 396 3657 2108 4496 495 393 -519 N ATOM 4516 CA GLU E 396 41.166 -32.229 -11.086 1.00 27.69 C ANISOU 4516 CA GLU E 396 3848 2051 4623 447 430 -554 C ATOM 4517 CB GLU E 396 41.104 -33.664 -10.542 1.00 29.27 C ANISOU 4517 CB GLU E 396 4134 2013 4973 547 344 -494 C ATOM 4518 CG GLU E 396 42.271 -34.530 -10.972 1.00 32.63 C ANISOU 4518 CG GLU E 396 4474 2363 5563 729 311 -631 C ATOM 4519 CD GLU E 396 42.372 -35.851 -10.218 1.00 36.07 C ANISOU 4519 CD GLU E 396 5002 2534 6168 858 191 -529 C ATOM 4520 OE1 GLU E 396 41.525 -36.109 -9.323 1.00 38.71 O ANISOU 4520 OE1 GLU E 396 5482 2756 6470 779 143 -330 O ATOM 4521 OE2 GLU E 396 43.304 -36.647 -10.530 1.00 42.02 O ANISOU 4521 OE2 GLU E 396 5684 3188 7095 1039 148 -649 O ATOM 4522 C GLU E 396 39.785 -31.557 -11.059 1.00 25.08 C ANISOU 4522 C GLU E 396 3601 1751 4176 284 471 -475 C ATOM 4523 O GLU E 396 39.134 -31.458 -12.082 1.00 25.02 O ANISOU 4523 O GLU E 396 3608 1763 4135 209 531 -560 O ATOM 4524 N ALA E 397 39.382 -31.055 -9.898 1.00 24.77 N ANISOU 4524 N ALA E 397 3603 1741 4069 238 435 -329 N ATOM 4525 CA ALA E 397 38.105 -30.350 -9.702 1.00 22.83 C ANISOU 4525 CA ALA E 397 3407 1538 3729 104 473 -267 C ATOM 4526 CB ALA E 397 37.845 -30.182 -8.227 1.00 22.80 C ANISOU 4526 CB ALA E 397 3447 1548 3667 81 431 -123 C ATOM 4527 C ALA E 397 38.054 -29.011 -10.421 1.00 21.75 C ANISOU 4527 C ALA E 397 3209 1549 3504 43 529 -331 C ATOM 4528 O ALA E 397 37.043 -28.663 -11.030 1.00 22.91 O ANISOU 4528 O ALA E 397 3380 1710 3614 -37 562 -349 O ATOM 4529 N ILE E 398 39.136 -28.247 -10.344 1.00 20.67 N ANISOU 4529 N ILE E 398 2993 1518 3341 75 531 -358 N ATOM 4530 CA ILE E 398 39.245 -27.004 -11.079 1.00 19.58 C ANISOU 4530 CA ILE E 398 2812 1492 3134 8 585 -403 C ATOM 4531 CB ILE E 398 40.575 -26.213 -10.741 1.00 19.57 C ANISOU 4531 CB ILE E 398 2713 1599 3124 24 586 -429 C ATOM 4532 CG1 ILE E 398 40.619 -25.880 -9.246 1.00 18.51 C ANISOU 4532 CG1 ILE E 398 2582 1481 2970 32 523 -352 C ATOM 4533 CD1 ILE E 398 41.963 -25.363 -8.757 1.00 20.95 C ANISOU 4533 CD1 ILE E 398 2779 1896 3284 56 495 -393 C ATOM 4534 CG2 ILE E 398 40.655 -24.936 -11.565 1.00 17.52 C ANISOU 4534 CG2 ILE E 398 2432 1422 2802 -73 651 -453 C ATOM 4535 C ILE E 398 39.063 -27.223 -12.597 1.00 19.20 C ANISOU 4535 C ILE E 398 2768 1457 3070 -19 639 -494 C ATOM 4536 O ILE E 398 38.259 -26.545 -13.226 1.00 17.87 O ANISOU 4536 O ILE E 398 2634 1320 2835 -95 659 -479 O ATOM 4537 N ILE E 399 39.791 -28.190 -13.148 1.00 20.46 N ANISOU 4537 N ILE E 399 2890 1594 3288 52 653 -593 N ATOM 4538 CA ILE E 399 39.703 -28.555 -14.570 1.00 20.68 C ANISOU 4538 CA ILE E 399 2920 1655 3284 28 710 -714 C ATOM 4539 CB ILE E 399 40.619 -29.774 -14.904 1.00 22.08 C ANISOU 4539 CB ILE E 399 3039 1784 3565 141 723 -855 C ATOM 4540 CG1 ILE E 399 42.093 -29.371 -14.774 1.00 21.85 C ANISOU 4540 CG1 ILE E 399 2876 1872 3554 198 754 -907 C ATOM 4541 CD1 ILE E 399 43.088 -30.515 -14.781 1.00 23.92 C ANISOU 4541 CD1 ILE E 399 3050 2078 3961 353 742 -1039 C ATOM 4542 CG2 ILE E 399 40.306 -30.345 -16.312 1.00 21.12 C ANISOU 4542 CG2 ILE E 399 2936 1684 3405 110 780 -1011 C ATOM 4543 C ILE E 399 38.254 -28.856 -14.984 1.00 21.30 C ANISOU 4543 C ILE E 399 3087 1671 3335 -37 690 -699 C ATOM 4544 O ILE E 399 37.753 -28.319 -15.969 1.00 21.55 O ANISOU 4544 O ILE E 399 3137 1788 3263 -112 713 -722 O ATOM 4545 N VAL E 400 37.593 -29.728 -14.229 1.00 21.79 N ANISOU 4545 N VAL E 400 3203 1590 3488 -18 641 -655 N ATOM 4546 CA VAL E 400 36.210 -30.104 -14.507 1.00 21.47 C ANISOU 4546 CA VAL E 400 3221 1492 3445 -94 623 -654 C ATOM 4547 CB VAL E 400 35.728 -31.255 -13.542 1.00 21.73 C ANISOU 4547 CB VAL E 400 3313 1344 3600 -85 586 -598 C ATOM 4548 CG1 VAL E 400 34.263 -31.478 -13.660 1.00 19.99 C ANISOU 4548 CG1 VAL E 400 3126 1090 3380 -194 578 -590 C ATOM 4549 CG2 VAL E 400 36.493 -32.517 -13.815 1.00 21.84 C ANISOU 4549 CG2 VAL E 400 3339 1224 3736 3 579 -696 C ATOM 4550 C VAL E 400 35.249 -28.902 -14.461 1.00 20.50 C ANISOU 4550 C VAL E 400 3099 1460 3229 -173 613 -571 C ATOM 4551 O VAL E 400 34.363 -28.774 -15.302 1.00 20.28 O ANISOU 4551 O VAL E 400 3080 1476 3150 -232 600 -610 O ATOM 4552 N ALA E 401 35.406 -28.048 -13.458 1.00 19.91 N ANISOU 4552 N ALA E 401 3010 1412 3141 -166 607 -470 N ATOM 4553 CA ALA E 401 34.606 -26.819 -13.352 1.00 19.36 C ANISOU 4553 CA ALA E 401 2933 1408 3014 -214 597 -410 C ATOM 4554 CB ALA E 401 34.872 -26.101 -12.008 1.00 17.52 C ANISOU 4554 CB ALA E 401 2687 1183 2788 -199 596 -333 C ATOM 4555 C ALA E 401 34.832 -25.862 -14.533 1.00 19.87 C ANISOU 4555 C ALA E 401 2992 1566 2990 -237 605 -427 C ATOM 4556 O ALA E 401 33.877 -25.259 -15.044 1.00 19.29 O ANISOU 4556 O ALA E 401 2928 1525 2877 -270 570 -403 O ATOM 4557 N MSE E 402 36.089 -25.714 -14.954 1.00 20.42 N ANISOU 4557 N MSE E 402 3042 1687 3029 -222 647 -461 N ATOM 4558 CA MSE E 402 36.416 -24.804 -16.059 1.00 21.29 C ANISOU 4558 CA MSE E 402 3161 1895 3034 -271 672 -454 C ATOM 4559 CB MSE E 402 37.926 -24.599 -16.154 1.00 21.70 C ANISOU 4559 CB MSE E 402 3161 2012 3074 -271 741 -491 C ATOM 4560 CG MSE E 402 38.500 -23.683 -15.106 1.00 22.22 C ANISOU 4560 CG MSE E 402 3194 2063 3185 -274 741 -428 C ATOM 4561 SE MSE E 402 40.412 -23.696 -15.293 0.90 27.13 SE ANISOU 4561 SE MSE E 402 3703 2793 3811 -278 825 -514 SE ATOM 4562 CE MSE E 402 40.877 -22.320 -13.992 1.00 24.57 C ANISOU 4562 CE MSE E 402 3347 2452 3536 -321 801 -441 C ATOM 4563 C MSE E 402 35.859 -25.299 -17.400 1.00 20.61 C ANISOU 4563 C MSE E 402 3105 1865 2859 -305 663 -518 C ATOM 4564 O MSE E 402 35.362 -24.495 -18.187 1.00 19.44 O ANISOU 4564 O MSE E 402 2995 1781 2610 -352 634 -461 O ATOM 4565 N VAL E 403 35.951 -26.621 -17.650 1.00 20.69 N ANISOU 4565 N VAL E 403 3106 1848 2909 -277 678 -639 N ATOM 4566 CA VAL E 403 35.357 -27.238 -18.838 1.00 21.22 C ANISOU 4566 CA VAL E 403 3197 1968 2897 -315 663 -740 C ATOM 4567 CB VAL E 403 35.749 -28.745 -19.039 1.00 22.85 C ANISOU 4567 CB VAL E 403 3389 2108 3184 -275 696 -911 C ATOM 4568 CG1 VAL E 403 34.962 -29.365 -20.219 1.00 22.24 C ANISOU 4568 CG1 VAL E 403 3339 2087 3026 -332 670 -1042 C ATOM 4569 CG2 VAL E 403 37.257 -28.917 -19.283 1.00 22.02 C ANISOU 4569 CG2 VAL E 403 3230 2058 3078 -225 785 -1003 C ATOM 4570 C VAL E 403 33.831 -27.076 -18.810 1.00 21.70 C ANISOU 4570 C VAL E 403 3278 2007 2959 -349 573 -688 C ATOM 4571 O VAL E 403 33.223 -26.611 -19.775 1.00 22.35 O ANISOU 4571 O VAL E 403 3382 2190 2919 -393 524 -677 O ATOM 4572 N PHE E 404 33.229 -27.437 -17.677 1.00 21.32 N ANISOU 4572 N PHE E 404 3216 1843 3042 -331 550 -651 N ATOM 4573 CA PHE E 404 31.791 -27.400 -17.481 1.00 21.21 C ANISOU 4573 CA PHE E 404 3184 1815 3059 -366 483 -626 C ATOM 4574 CB PHE E 404 31.482 -27.898 -16.078 1.00 20.30 C ANISOU 4574 CB PHE E 404 3054 1582 3076 -361 502 -585 C ATOM 4575 CG PHE E 404 30.035 -27.900 -15.746 1.00 19.75 C ANISOU 4575 CG PHE E 404 2939 1514 3051 -412 461 -575 C ATOM 4576 CD1 PHE E 404 29.247 -29.023 -16.055 1.00 19.38 C ANISOU 4576 CD1 PHE E 404 2879 1427 3057 -483 446 -667 C ATOM 4577 CE1 PHE E 404 27.907 -29.040 -15.754 1.00 19.00 C ANISOU 4577 CE1 PHE E 404 2759 1402 3058 -547 417 -672 C ATOM 4578 CZ PHE E 404 27.319 -27.946 -15.109 1.00 19.40 C ANISOU 4578 CZ PHE E 404 2745 1515 3110 -518 407 -596 C ATOM 4579 CE2 PHE E 404 28.097 -26.822 -14.789 1.00 17.30 C ANISOU 4579 CE2 PHE E 404 2507 1267 2799 -435 418 -512 C ATOM 4580 CD2 PHE E 404 29.458 -26.815 -15.107 1.00 15.18 C ANISOU 4580 CD2 PHE E 404 2315 974 2477 -394 445 -496 C ATOM 4581 C PHE E 404 31.176 -26.003 -17.703 1.00 21.45 C ANISOU 4581 C PHE E 404 3204 1924 3023 -364 423 -525 C ATOM 4582 O PHE E 404 30.026 -25.880 -18.163 1.00 22.44 O ANISOU 4582 O PHE E 404 3300 2097 3129 -384 344 -535 O ATOM 4583 N SER E 405 31.953 -24.969 -17.400 1.00 21.06 N ANISOU 4583 N SER E 405 3173 1878 2951 -336 451 -437 N ATOM 4584 CA SER E 405 31.531 -23.571 -17.521 1.00 21.22 C ANISOU 4584 CA SER E 405 3201 1919 2941 -322 396 -331 C ATOM 4585 CB SER E 405 32.564 -22.651 -16.867 1.00 20.19 C ANISOU 4585 CB SER E 405 3090 1748 2835 -309 450 -261 C ATOM 4586 OG SER E 405 33.724 -22.537 -17.685 1.00 22.95 O ANISOU 4586 OG SER E 405 3477 2159 3084 -349 505 -260 O ATOM 4587 C SER E 405 31.306 -23.154 -18.975 1.00 22.42 C ANISOU 4587 C SER E 405 3398 2173 2949 -348 331 -301 C ATOM 4588 O SER E 405 30.560 -22.202 -19.254 1.00 23.42 O ANISOU 4588 O SER E 405 3532 2307 3060 -324 239 -211 O ATOM 4589 N GLN E 406 31.952 -23.865 -19.900 1.00 23.01 N ANISOU 4589 N GLN E 406 3502 2329 2912 -392 374 -379 N ATOM 4590 CA GLN E 406 31.820 -23.613 -21.329 1.00 23.93 C ANISOU 4590 CA GLN E 406 3671 2581 2840 -437 323 -363 C ATOM 4591 CB GLN E 406 30.363 -23.731 -21.769 1.00 23.93 C ANISOU 4591 CB GLN E 406 3642 2627 2824 -428 184 -375 C ATOM 4592 CG GLN E 406 29.800 -25.108 -21.530 1.00 25.61 C ANISOU 4592 CG GLN E 406 3790 2817 3125 -445 190 -542 C ATOM 4593 CD GLN E 406 28.374 -25.265 -22.015 1.00 26.20 C ANISOU 4593 CD GLN E 406 3807 2964 3185 -456.

52. 581 C ATOM 4594 OE1 GLN E 406 27.534 -24.417 -21.751 1.00 27.21 O ANISOU 4594 OE1 GLN E 406 3891 3085 3361 -406 -42 -484 O ATOM 4595 NE2 GLN E 406 28.100 -26.358 -22.741 1.00 26.20 N ANISOU 4595 NE2 GLN E 406 3793 3035 3128 -519.

35. 744 N ATOM 4596 C GLN E 406 32.420 -22.265 -21.765 1.00 24.66 C ANISOU 4596 C GLN E 406 3837 2702 2830 -463 327 -203 C ATOM 4597 O GLN E 406 32.100 -21.780 -22.848 1.00 26.26 O ANISOU 4597 O GLN E 406 4104 3005 2869 -497 254 -125 O ATOM 4598 N GLU E 407 33.294 -21.675 -20.941 1.00 23.80 N ANISOU 4598 N GLU E 407 3726 2506 2810 -459 407 -149 N ATOM 4599 CA GLU E 407 33.961 -20.391 -21.287 1.00 25.17 C ANISOU 4599 CA GLU E 407 3974 2678 2913 -513 429 1 C ATOM 4600 CB GLU E 407 34.926 -19.945 -20.188 1.00 24.30 C ANISOU 4600 CB GLU E 407 3829 2469 2934 -515 519 5 C ATOM 4601 CG GLU E 407 34.281 -19.528 -18.878 1.00 24.55 C ANISOU 4601 CG GLU E 407 3821 2356 3150 -436 467 19 C ATOM 4602 CD GLU E 407 34.947 -18.299 -18.237 1.00 25.54 C ANISOU 4602 CD GLU E 407 3969 2380 3355 -464 499 96 C ATOM 4603 OE1 GLU E 407 35.873 -17.724 -18.827 1.00 30.35 O ANISOU 4603 OE1 GLU E 407 4626 3019 3887 -559 558 160 O ATOM 4604 OE2 GLU E 407 34.530 -17.876 -17.153 1.00 23.13 O ANISOU 4604 OE2 GLU E 407 3631 1969 3188 -407 470 83 O ATOM 4605 C GLU E 407 34.732 -20.428 -22.598 1.00 27.34 C ANISOU 4605 C GLU E 407 4309 3114 2966 -616 494 10 C ATOM 4606 O GLU E 407 35.326 -21.447 -22.949 1.00 27.53 O ANISOU 4606 O GLU E 407 4289 3241 2928 -640 584 -143 O ATOM 4607 N ASP E 408 34.720 -19.296 -23.313 1.00 30.09 N ANISOU 4607 N ASP E 408 4761 3478 3194 -677 453 192 N ATOM 4608 CA ASP E 408 35.466 -19.149 -24.567 1.00 32.41 C ANISOU 4608 CA ASP E 408 5129 3945 3239 -807 529 238 C ATOM 4609 CB ASP E 408 35.129 -17.845 -25.296 1.00 34.46 C ANISOU 4609 CB ASP E 408 5534 4184 3374 -865 434 495 C ATOM 4610 CG ASP E 408 35.833 -17.727 -26.652 1.00 38.94 C ANISOU 4610 CG ASP E 408 6196 4964 3636 -1025 519 562 C ATOM 4611 OD1 ASP E 408 35.458 -18.436 -27.618 1.00 39.82 O ANISOU 4611 OD1 ASP E 408 6324 5271 3536 -1043 486 487 O ATOM 4612 OD2 ASP E 408 36.777 -16.908 -26.746 1.00 42.86 O ANISOU 4612 OD2 ASP E 408 6747 5443 4095 -1150 628 682 O ATOM 4613 C ASP E 408 36.971 -19.282 -24.378 1.00 32.45 C ANISOU 4613 C ASP E 408 5078 4004 3248 -892 721 155 C ATOM 4614 O ASP E 408 37.656 -19.768 -25.273 1.00 34.09 O ANISOU 4614 O ASP E 408 5278 4400 3273 -979 829 69 O ATOM 4615 N ACYS E 409 37.497 -18.881 -23.224 0.50 31.13 N ANISOU 4615 N ACYS E 409 4853 3694 3283 -867 764 157 N ATOM 4616 N BCYS E 409 37.455 -18.823 -23.224 0.50 31.33 N ANISOU 4616 N BCYS E 409 4884 3713 3309 -867 757 167 N ATOM 4617 CA ACYS E 409 38.945 -18.986 -22.993 0.50 31.70 C ANISOU 4617 CA ACYS E 409 4839 3830 3375 -943 929 67 C ATOM 4618 CA BCYS E 409 38.853 -18.961 -22.819 0.50 31.92 C ANISOU 4618 CA BCYS E 409 4865 3831 3435 -926 915 70 C ATOM 4619 CB ACYS E 409 39.418 -17.964 -21.963 0.50 31.37 C ANISOU 4619 CB ACYS E 409 4782 3631 3504 -966 941 149 C ATOM 4620 CB BCYS E 409 39.050 -18.424 -21.402 0.50 30.51 C ANISOU 4620 CB BCYS E 409 4633 3474 3486 -876 897 85 C ATOM 4621 SG ACYS E 409 39.457 -18.589 -20.296 0.50 30.93 S ANISOU 4621 SG ACYS E 409 4597 3457 3698 -823 915 5 S ATOM 4622 SG BCYS E 409 39.461 -16.682 -21.315 0.50 36.34 S ANISOU 4622 SG BCYS E 409 5462 4091 4256 -1005 908 284 S ATOM 4623 C ACYS E 409 39.403 -20.401 -22.601 0.50 30.56 C ANISOU 4623 C ACYS E 409 4560 3745 3307 -857 994 -170 C ATOM 4624 C BCYS E 409 39.290 -20.414 -22.846 0.50 31.07 C ANISOU 4624 C BCYS E 409 4642 3832 3331 -867 989 -162 C ATOM 4625 O ACYS E 409 40.607 -20.690 -22.587 0.50 31.33 O ANISOU 4625 O ACYS E 409 4558 3935 3409 -897 1126 -280 O ATOM 4626 O BCYS E 409 40.354 -20.744 -23.379 0.50 32.50 O ANISOU 4626 O BCYS E 409 4760 4166 3424 -938 1128 -266 O ATOM 4627 N MSE E 410 38.447 -21.267 -22.266 1.00 28.89 N ANISOU 4627 N MSE E 410 4337 3470 3171 -740 899 -246 N ATOM 4628 CA MSE E 410 38.702 -22.687 -22.159 1.00 27.78 C ANISOU 4628 CA MSE E 410 4109 3364 3084 -665 940 -452 C ATOM 4629 CB MSE E 410 37.602 -23.336 -21.317 1.00 25.84 C ANISOU 4629 CB MSE E 410 3858 2970 2988 -556 826 -475 C ATOM 4630 CG MSE E 410 37.745 -24.812 -21.107 1.00 24.62 C ANISOU 4630 CG MSE E 410 3640 2790 2925 -480 849 -661 C ATOM 4631 SE MSE E 410 36.814 -25.805 -22.457 0.90 25.74 SE ANISOU 4631 SE MSE E 410 3827 3028 2924 -506 808 -801 SE ATOM 4632 CE MSE E 410 35.017 -25.128 -22.097 1.00 23.87 C ANISOU 4632 CE MSE E 410 3650 2703 2716 -500 633 -631 C ATOM 4633 C MSE E 410 38.792 -23.291 -23.566 1.00 29.33 C ANISOU 4633 C MSE E 410 4324 3746 3072 -725 995 -564 C ATOM 4634 O MSE E 410 39.716 -24.018 -23.894 1.00 29.96 O ANISOU 4634 O MSE E 410 4323 3928 3131 -726 1112 -737 O ATOM 4635 N ILE E 411 37.828 -22.957 -24.405 1.00 30.56 N ANISOU 4635 N ILE E 411 4583 3960 3069 -769 906 -474 N ATOM 4636 CA ILE E 411 37.776 -23.470 -25.766 1.00 32.47 C ANISOU 4636 CA ILE E 411 4859 4406 3073 -837 938 -578 C ATOM 4637 CB ILE E 411 36.401 -23.150 -26.397 1.00 32.92 C ANISOU 4637 CB ILE E 411 5019 4490 3001 -847 769 -462 C ATOM 4638 CG1 ILE E 411 35.373 -24.172 -25.895 1.00 33.37 C ANISOU 4638 CG1 ILE E 411 5025 4439 3216 -745 664 -594 C ATOM 4639 CD1 ILE E 411 33.977 -23.673 -25.783 1.00 34.15 C ANISOU 4639 CD1 ILE E 411 5163 4473 3339 -708 481 -458 C ATOM 4640 CG2 ILE E 411 36.431 -23.283 -27.907 1.00 35.77 C ANISOU 4640 CG2 ILE E 411 5446 5105 3040 -954 792 -507 C ATOM 4641 C ILE E 411 38.973 -22.985 -26.599 1.00 34.59 C ANISOU 4641 C ILE E 411 5130 4868 3144 -972 1100 -571 C ATOM 4642 O ILE E 411 39.547 -23.735 -27.392 1.00 36.40 O ANISOU 4642 O ILE E 411 5312 5278 3240 -1009 1214 -766 O ATOM 4643 N LYS E 412 39.383 -21.744 -26.380 1.00 34.85 N ANISOU 4643 N LYS E 412 5209 4862 3172 -1052 1123 -363 N ATOM 4644 CA LYS E 412 40.525 -21.193 -27.085 1.00 36.94 C ANISOU 4644 CA LYS E 412 5471 5303 3261 -1213 1291 -333 C ATOM 4645 CB LYS E 412 40.472 -19.660 -27.055 1.00 37.70 C ANISOU 4645 CB LYS E 412 5690 5312 3323 -1323 1253 -33 C ATOM 4646 CG LYS E 412 39.344 -19.044 -27.912 1.00 38.14 C ANISOU 4646 CG LYS E 412 5929 5383 3179 -1358 1097 184 C ATOM 4647 CD LYS E 412 39.476 -19.441 -29.388 1.00 42.37 C ANISOU 4647 CD LYS E 412 6522 6218 3360 -1478 1167 132 C ATOM 4648 CE LYS E 412 38.440 -18.757 -30.263 1.00 43.95 C ANISOU 4648 CE LYS E 412 6909 6454 3335 -1517 992 376 C ATOM 4649 NZ LYS E 412 37.050 -19.198 -29.938 1.00 43.30 N ANISOU 4649 NZ LYS E 412 6823 6258 3371 -1341 770 345 N ATOM 4650 C LYS E 412 41.870 -21.724 -26.575 1.00 37.07 C ANISOU 4650 C LYS E 412 5308 5363 3414 -1197 1460 -534 C ATOM 4651 O LYS E 412 42.886 -21.588 -27.252 1.00 39.36 O ANISOU 4651 O LYS E 412 5545 5853 3557 -1327 1633 -594 O ATOM 4652 N ALA E 413 41.872 -22.336 -25.390 1.00 35.02 N ANISOU 4652 N ALA E 413 4949 4932 3426 -1041 1408 -635 N ATOM 4653 CA ALA E 413 43.087 -22.942 -24.833 1.00 34.68 C ANISOU 4653 CA ALA E 413 4723 4918 3536 -985 1526 -827 C ATOM 4654 CB ALA E 413 43.016 -22.990 -23.309 1.00 31.70 C ANISOU 4654 CB ALA E 413 4291 4318 3437 -852 1426 -795 C ATOM 4655 C ALA E 413 43.387 -24.329 -25.422 1.00 35.53 C ANISOU 4655 C ALA E 413 4738 5144 3617 -907 1600 -1111 C ATOM 4656 O ALA E 413 44.438 -24.908 -25.156 1.00 36.10 O ANISOU 4656 O ALA E 413 4646 5265 3807 -844 1701 -1297 O ATOM 4657 N VAL E 414 42.471 -24.854 -26.229 1.00 36.17 N ANISOU 4657 N VAL E 414 4917 5270 3556 -905 1543 -1161 N ATOM 4658 CA VAL E 414 42.703 -26.137 -26.896 1.00 37.60 C ANISOU 4658 CA VAL E 414 5026 5559 3703 -846 1616 -1457 C ATOM 4659 CB VAL E 414 41.425 -26.689 -27.557 1.00 37.84 C ANISOU 4659 CB VAL E 414 5176 5586 3615 -840 1499 -1498 C ATOM 4660 CG1 VAL E 414 41.758 -27.878 -28.499 1.00 39.24 C ANISOU 4660 CG1 VAL E 414 5290 5919 3703 -822 1602 -1834 C ATOM 4661 CG2 VAL E 414 40.407 -27.088 -26.498 1.00 33.57 C ANISOU 4661 CG2 VAL E 414 4671 4769 3316 -713 1324 -1430 C ATOM 4662 C VAL E 414 43.829 -26.037 -27.933 1.00 41.28 C ANISOU 4662 C VAL E 414 5406 6318 3960 -969 1828 -1600 C ATOM 4663 O VAL E 414 43.854 -25.126 -28.772 1.00 41.91 O ANISOU 4663 O VAL E 414 5575 6580 3769 -1151 1889 -1455 O ATOM 4664 N ARG E 415 44.752 -26.995 -27.862 1.00 43.28 N ANISOU 4664 N ARG E 415 5485 6615 4345 -866 1940 -1885 N ATOM 4665 CA ARG E 415 45.838 -27.092 -28.822 1.00 47.04 C ANISOU 4665 CA ARG E 415 5837 7389 4648 -962 2163 -2091 C ATOM 4666 CB ARG E 415 47.205 -27.002 -28.123 1.00 47.50 C ANISOU 4666 CB ARG E 415 5672 7467 4909 -912 2278 -2175 C ATOM 4667 CG ARG E 415 47.450 -25.686 -27.389 1.00 46.34 C ANISOU 4667 CG ARG E 415 5545 7256 4804 -1020 2250 -1881 C ATOM 4668 CD ARG E 415 47.536 -24.502 -28.344 1.00 49.52 C ANISOU 4668 CD ARG E 415 6053 7875 4887 -1292 2366 -1695 C ATOM 4669 NE ARG E 415 47.747 -23.254 -27.607 1.00 48.95 N

ANISOU 4669 NE ARG E 415 6011 7694 4895 -1396 2332 -1427 N

ATOM 4670 CZ ARG E 415 46.795 -22.365 -27.330 1.00 46.89 C

ANISOU 4670 CZ ARG E 415 5952 7256 4608 -1446 2181 -1130 C

ATOM 4671 NH1 ARG E 415 45.553 -22.573 -27.751 1.00 46.50 N

ANISOU 4671 NH1 ARG E 415 6082 7142 4444 -1404 2044 -1050 N

ATOM 4672 NH2 ARG E 415 47.094 -21.257 -26.644 1.00 44.45 N

ANISOU 4672 NH2 ARG E 415 5654 6838 4397 -1538 2164 -932 N

ATOM 4673 C ARG E 415 45.722 -28.376 -29.633 1.00 49.40 C

ANISOU 4673 C ARG E 415 6100 7778 4892 -885 2213 -2430 C

ATOM 4674 O ARG E 415 45.571 -29.466 -29.075 1.00 49.22 O

ANISOU 4674 O ARG E 415 6023 7550 5130 -691 2135 -2605 O

ATOM 4675 N GLY E 416 45.791 -28.237 -30.952 1.00 52.08 N

ANISOU 4675 N GLY E 416 6480 8422 4887 -1048 2344 -2521 N

ATOM 4676 CA GLY E 416 45.624 -29.371 -31.844 1.00 54.89 C

ANISOU 4676 CA GLY E 416 6816 8897 5143 -1004 2397 -2865 C

ATOM 4677 C GLY E 416 44.169 -29.796 -31.969 1.00 53.94 C

ANISOU 4677 C GLY E 416 6874 8627 4993 -972 2190 -2820 C

ATOM 4678 O GLY E 416 43.287 -29.229 -31.316 1.00 51.70 O

ANISOU 4678 O GLY E 416 6715 8147 4783 -967 2007 -2522 O

ATOM 4679 N ASP E 417 43.932 -30.798 -32.812 1.00 56.14 N

ANISOU 4679 N ASP E 417 7149 9009 5171 -954 2224 -3142 N

ATOM 4680 CA ASP E 417 42.594 -31.308 -33.083 1.00 55.99 C

ANISOU 4680 CA ASP E 417 7273 8893 5107 -947 2041 -3164 C

ATOM 4681 CB ASP E 417 42.535 -31.971 -34.471 1.00 59.31 C

ANISOU 4681 CB ASP E 417 7703 9606 5227 -1034 2138 -3503 C

ATOM 4682 CG ASP E 417 42.443 -30.958 -35.618 1.00 61.53 C

ANISOU 4682 CG ASP E 417 8097 10274 5009 -1270 2196 -3338 C

ATOM 4683 OD1 ASP E 417 42.191 -29.761 -35.352 1.00 58.40 O

ANISOU 4683 OD1 ASP E 417 7803 9867 4522 -1359 2119 -2936 O

ATOM 4684 OD2 ASP E 417 42.607 -31.366 -36.801 1.00 64.87 O

ANISOU 4684 OD2 ASP E 417 8516 11011 5120 -1369 2315 -3613 O

ATOM 4685 C ASP E 417 42.153 -32.295 -32.013 1.00 54.22 C

ANISOU 4685 C ASP E 417 7020 8277 5303 -748 1903 -3244 C

ATOM 4686 O ASP E 417 42.985 -32.986 -31.415 1.00 54.68 O

ANISOU 4686 O ASP E 417 6940 8187 5651 -592 1974 -3422 O

ATOM 4687 N LEU E 418 40.845 -32.359 -31.782 1.00 52.57 N

ANISOU 4687 N LEU E 418 6940 7908 5127 -756 1703 -3107 N

ATOM 4688 CA LEU E 418 40.294 -33.303 -30.826 1.00 51.40 C

ANISOU 4688 CA LEU E 418 6787 7397 5344 -610 1576 -3164 C

ATOM 4689 CB LEU E 418 39.353 -32.585 -29.850 1.00 48.14 C

ANISOU 4689 CB LEU E 418 6464 6792 5037 -613 1398 -2795 C

ATOM 4690 CG LEU E 418 39.926 -31.400 -29.056 1.00 45.99 C

ANISOU 4690 CG LEU E 418 6170 6504 4798 -611 1421 -2486 C

ATOM 4691 CD1 LEU E 418 38.849 -30.744 -28.220 1.00 44.92 C

ANISOU 4691 CD1 LEU E 418 6125 6198 4746 -616 1247 -2179 C

ATOM 4692 CD2 LEU E 418 41.082 -31.819 -28.178 1.00 46.73 C

ANISOU 4692 CD2 LEU E 418 6131 6455 5169 -468 1509 -2568 C

ATOM 4693 C LEU E 418 39.612 -34.486 -31.533 1.00 53.69 C

ANISOU 4693 C LEU E 418 7109 7665 5627 -615 1533 -3488 C

ATOM 4694 O LEU E 418 38.647 -34.299 -32.289 1.00 54.45 O

ANISOU 4694 O LEU E 418 7301 7912 5477 -742 1440 -3471 O

ATOM 4695 N ASN E 419 40.129 -35.693 -31.277 1.00 55.13 N

ANISOU 4695 N ASN E 419 7208 7649 6090 -474 1588 -3786 N

ATOM 4696 CA ASN E 419 39.644 -36.931 -31.904 1.00 57.91 C

ANISOU 4696 CA ASN E 419 7578 7933 6493 -469 1567 -4150 C

ATOM 4697 CB ASN E 419 40.546 -37.300 -33.088 1.00 61.18 C

ANISOU 4697 CB ASN E 419 7904 8639 6703 -488 1763 -4536 C

ATOM 4698 CG ASN E 419 40.444 -36.311 -34.223 1.00 62.11 C

ANISOU 4698 CG ASN E 419 8073 9206 6320 -687 1822 -4458 C

ATOM 4699 OD1 ASN E 419 39.366 -36.093 -34.773 1.00 61.35 O

ANISOU 4699 OD1 ASN E 419 8092 9224 5995 -820 1694 -4388 O

ATOM 4700 ND2 ASN E 419 41.572 -35.692 -34.576 1.00 64.20 N

ANISOU 4700 ND2 ASN E 419 8248 9736 6409 -717 2012 -4458 N

ATOM 4701 C ASN E 419 39.519 -38.140 -30.958 1.00 58.48 C

ANISOU 4701 C ASN E 419 7640 7561 7019 -310 1493 -4262 C ATOM 4702 O ASN E 419 39.706 -39.289 -31.387 1.00 60.83 O ANISOU 4702 O ASN E 419 7906 7757 7451 -247 1539 -4636 O ATOM 4703 N PHE E 420 39.191 -37.883 -29.687 1.00 56.70 N ANISOU 4703 N PHE E 420 7451 7072 7023 -252 1380 -3940 N ATOM 4704 CA PHE E 420 39.084 -38.931 -28.651 1.00 57.43 C ANISOU 4704 CA PHE E 420 7556 6734 7531 -114 1302 -3962 C ATOM 4705 CB PHE E 420 38.919 -38.322 -27.244 1.00 54.05 C ANISOU 4705 CB PHE E 420 7156 6122 7256 -69 1207 -3556 C ATOM 4706 CG PHE E 420 40.157 -37.660 -26.718 1.00 53.02 C ANISOU 4706 CG PHE E 420 6924 6072 7150 40 1288 -3429 C ATOM 4707 CD1 PHE E 420 40.232 -36.271 -26.623 1.00 49.71 C ANISOU 4707 CD1 PHE E 420 6500 5880 6506 -48 1302 -3156 C ATOM 4708 CE1 PHE E 420 41.378 -35.643 -26.140 1.00 48.97 C ANISOU 4708 CE1 PHE E 420 6301 5865 6440 27 1377 -3055 C ATOM 4709 CZ PHE E 420 42.477 -36.409 -25.744 1.00 51.30 C ANISOU 4709 CZ PHE E 420 6475 6032 6983 212 1429 -3226 C ATOM 4710 CE2 PHE E 420 42.419 -37.803 -25.839 1.00 54.45 C ANISOU 4710 CE2 PHE E 420 6879 6193 7615 329 1405 -3490 C ATOM 4711 CD2 PHE E 420 41.259 -38.425 -26.323 1.00 54.30 C ANISOU 4711 CD2 PHE E 420 6985 6074 7573 234 1341 -3591 C ATOM 4712 C PHE E 420 37.958 -39.927 -28.902 1.00 59.71 C ANISOU 4712 C PHE E 420 7933 6829 7924 -188 1203 -4135 C ATOM 4713 O PHE E 420 36.885 -39.562 -29.385 1.00 59.38 O ANISOU 4713 O PHE E 420 7955 6933 7674 -352 1122 -4078 O ATOM 4714 N VAL E 421 38.221 -41.179 -28.526 1.00 62.76 N ANISOU 4714 N VAL E 421 8318 6873 8656 -62 1198 -4339 N ATOM 4715 CA VAL E 421 37.341 -42.318 -28.779 1.00 66.10 C ANISOU 4715 CA VAL E 421 8817 7058 9241 -128 1126 -4568 C ATOM 4716 CB VAL E 421 37.809 -43.068 -30.056 1.00 69.65 C ANISOU 4716 CB VAL E 421 9215 7633 9617 -116 1235 -5067 C ATOM 4717 CG1 VAL E 421 37.690 -44.582 -29.918 1.00 73.52 C ANISOU 4717 CG1 VAL E 421 9747 7695 10491 -41 1203 -5363 C ATOM 4718 CG2 VAL E 421 37.063 -42.546 -31.282 1.00 70.73 C ANISOU 4718 CG2 VAL E 421 9372 8169 9332 -327 1231 -5178 C ATOM 4719 C VAL E 421 37.312 -43.237 -27.547 1.00 66.76 C ANISOU 4719 C VAL E 421 8958 6647 9763 -10 1048 -4463 C ATOM 4720 O VAL E 421 38.339 -43.406 -26.881 1.00 67.09 O ANISOU 4720 O VAL E 421 8949 6536 10006 185 1081 -4409 O ATOM 4721 N ASN E 422 36.145 -43.820 -27.243 1.00 67.53 N ANISOU 4721 N ASN E 422 9155 6503 9999 -136 942 -4424 N ATOM 4722 CA ASN E 422 35.987 -44.671 -26.041 1.00 68.08 C ANISOU 4722 CA ASN E 422 9309 6098 10459 -68 865 -4271 C ATOM 4723 CB ASN E 422 34.522 -44.727 -25.572 1.00 67.27 C ANISOU 4723 CB ASN E 422 9296 5877 10386 -278 760 -4080 C ATOM 4724 CG ASN E 422 33.535 -44.977 -26.713 1.00 69.70 C ANISOU 4724 CG ASN E 422 9604 6341 10538 -481 739 -4363 C ATOM 4725 OD1 ASN E 422 32.448 -44.388 -26.738 1.00 68.72 O ANISOU 4725 OD1 ASN E 422 9477 6388 10245 -657 670 -4214 O ATOM 4726 ND2 ASN E 422 33.905 -45.848 -27.657 1.00 72.67 N ANISOU 4726 ND2 ASN E 422 9970 6669 10973 -451 789 -4791 N ATOM 4727 C ASN E 422 36.580 -46.085 -26.139 1.00 71.50 C ANISOU 4727 C ASN E 422 9766 6157 11244 78 884 -4587 C ATOM 4728 O ASN E 422 36.751 -46.632 -27.227 1.00 74.15 O ANISOU 4728 O ASN E 422 10065 6559 11547 73 946 -5000 O ATOM 4729 N ARG E 427 33.161 -42.328 -30.481 1.00 65.32 N ANISOU 4729 N ARG E 427 8875 7278 8664 -761 800 -4699 N ATOM 4730 CA ARG E 427 33.763 -40.998 -30.490 1.00 62.98 C ANISOU 4730 CA ARG E 427 8546 7283 8101 -712 849 -4431 C ATOM 4731 CB ARG E 427 33.673 -40.369 -31.883 1.00 65.03 C ANISOU 4731 CB ARG E 427 8792 8005 7911 -823 864 -4564 C ATOM 4732 CG ARG E 427 34.458 -39.089 -31.984 1.00 64.47 C ANISOU 4732 CG ARG E 427 8699 8216 7579 -784 943 -4317 C ATOM 4733 CD ARG E 427 33.754 -38.015 -32.796 1.00 67.22 C ANISOU 4733 CD ARG E 427 9082 8944 7515 -926 854 -4158 C ATOM 4734 NE ARG E 427 34.445 -36.739 -32.601 1.00 67.49 N ANISOU 4734 NE ARG E 427 9116 9147 7382 -892 917 -3843 N ATOM 4735 CZ ARG E 427 35.598 -36.405 -33.186 1.00 69.71 C ANISOU 4735 CZ ARG E 427 9366 9652 7467 -875 1082 -3922 C ATOM 4736 NH1 ARG E 427 36.196 -37.243 -34.034 1.00 71.76 N ANISOU 4736 NH1 ARG E 427 9587 10022 7658 -875 1208 -4324 N ATOM 4737 NH2 ARG E 427 36.152 -35.226 -32.920 1.00 67.88 N ANISOU 4737 NH2 ARG E 427 9137 9538 7117 -868 1131 -3614 N ATOM 4738 C ARG E 427 33.075 -40.091 -29.485 1.00 58.80 C ANISOU 4738 C ARG E 427 8035 6711 7596 -740 749 -3994 C ATOM 4739 O ARG E 427 31.865 -39.867 -29.575 1.00 58.91 O ANISOU 4739 O ARG E 427 8061 6791 7533 -873 626 -3912 O ATOM 4740 N LEU E 428 33.848 -39.555 -28.545 1.00 55.36 N ANISOU 4740 N LEU E 428 7586 6185 7263 -612 800 -3735 N ATOM 4741 CA LEU E 428 33.293 -38.797 -27.419 1.00 50.88 C ANISOU 4741 CA LEU E 428 7034 5531 6765 -619 721 -3349 C ATOM 4742 CB LEU E 428 34.399 -38.397 -26.432 1.00 48.72 C ANISOU 4742 CB LEU E 428 6740 5151 6618 -464 792 -3144 C ATOM 4743 CG LEU E 428 35.420 -39.432 -25.919 1.00 49.33 C ANISOU 4743 CG LEU E 428 6806 4945 6991 -304 858 -3284 C ATOM 4744 CD1 LEU E 428 36.268 -38.834 -24.795 1.00 44.63 C ANISOU 4744 CD1 LEU E 428 6182 4285 6491 -173 879 -3013 C ATOM 4745 CD2 LEU E 428 34.776 -40.760 -25.451 1.00 49.60 C ANISOU 4745 CD2 LEU E 428 6906 4603 7335 -323 795 -3387 C ATOM 4746 C LEU E 428 32.532 -37.565 -27.894 1.00 49.08 C ANISOU 4746 C LEU E 428 6802 5617 6229 -725 643 -3163 C ATOM 4747 O LEU E 428 32.874 -36.983 -28.932 1.00 49.55 O ANISOU 4747 O LEU E 428 6855 5985 5989 -757 677 -3230 O ATOM 4748 N ASN E 429 31.494 -37.179 -27.148 1.00 46.94 N ANISOU 4748 N ASN E 429 6534 5270 6032 -780 538 -2933 N ATOM 4749 CA ASN E 429 30.814 -35.909 -27.424 1.00 45.15 C ANISOU 4749 CA ASN E 429 6294 5299 5563 -837 448 -2718 C ATOM 4750 CB ASN E 429 29.427 -35.795 -26.731 1.00 44.53 C ANISOU 4750 CB ASN E 429 6183 5130 5604 -909 324 -2571 C ATOM 4751 CG ASN E 429 29.505 -35.650 -25.216 1.00 43.04 C ANISOU 4751 CG ASN E 429 5995 4702 5656 -844 356 -2335 C ATOM 4752 OD1 ASN E 429 30.552 -35.375 -24.647 1.00 44.36 O ANISOU 4752 OD1 ASN E 429 6185 4799 5871 -736 441 -2227 O ATOM 4753 ND2 ASN E 429 28.369 -35.826 -24.559 1.00 44.32 N ANISOU 4753 ND2 ASN E 429 6122 4763 5956 -921 286 -2262 N ATOM 4754 C ASN E 429 31.770 -34.724 -27.176 1.00 42.35 C ANISOU 4754 C ASN E 429 5946 5058 5088 -750 517 -2486 C ATOM 4755 O ASN E 429 32.811 -34.903 -26.528 1.00 41.08 O ANISOU 4755 O ASN E 429 5779 4756 5072 -648 619 -2464 O ATOM 4756 N PRO E 430 31.476 -33.549 -27.774 1.00 41.73 N ANISOU 4756 N PRO E 430 5879 5236 4742 -793 458 -2330 N ATOM 4757 CA PRO E 430 32.316 -32.355 -27.629 1.00 39.46 C ANISOU 4757 CA PRO E 430 5608 5050 4333 -744 520 -2107 C ATOM 4758 CB PRO E 430 31.423 -31.252 -28.194 1.00 40.25 C ANISOU 4758 CB PRO E 430 5736 5353 4205 -805 385 -1924 C ATOM 4759 CG PRO E 430 30.653 -31.948 -29.274 1.00 42.76 C ANISOU 4759 CG PRO E 430 6052 5820 4376 -896 299 -2151 C ATOM 4760 CD PRO E 430 30.346 -33.303 -28.705 1.00 43.03 C ANISOU 4760 CD PRO E 430 6044 5611 4695 -894 315 -2363 C ATOM 4761 C PRO E 430 32.774 -32.033 -26.201 1.00 36.38 C ANISOU 4761 C PRO E 430 5201 4442 4180 -650 563 -1910 C ATOM 4762 O PRO E 430 33.960 -31.739 -25.993 1.00 35.32 O ANISOU 4762 O PRO E 430 5056 4315 4049 -592 673 -1876 O ATOM 4763 N MSE E 431 31.873 -32.122 -25.223 1.00 34.13 N ANISOU 4763 N MSE E 431 4901 3985 4083 -644 482 -1799 N ATOM 4764 CA MSE E 431 32.236 -31.766 -23.826 1.00 31.35 C ANISOU 4764 CA MSE E 431 4538 3456 3919 -566 515 -1608 C ATOM 4765 CB MSE E 431 30.985 -31.620 -22.945 1.00 30.30 C ANISOU 4765 CB MSE E 431 4383 3219 3912 -594 423 -1477 C ATOM 4766 CG MSE E 431 30.087 -30.421 -23.323 1.00 29.63 C ANISOU 4766 CG MSE E 431 4282 3300 3676 -624 317 -1334 C ATOM 4767 SE MSE E 431 30.966 -28.722 -22.996 0.90 32.22 SE ANISOU 4767 SE MSE E 431 4642 3693 3906 -556 353 -1079 SE ATOM 4768 CE MSE E 431 31.056 -28.819 -21.067 1.00 26.36 C ANISOU 4768 CE MSE E 431 3867 2715 3434 -492 401 -968 C ATOM 4769 C MSE E 431 33.244 -32.741 -23.208 1.00 30.85 C ANISOU 4769 C MSE E 431 4469 3203 4050 -485 609 -1710 C ATOM 4770 O MSE E 431 34.119 -32.348 -22.445 1.00 29.27 O ANISOU 4770 O MSE E 431 4255 2950 3916 -408 662 -1595 O ATOM 4771 N HIS E 432 33.128 -34.014 -23.562 1.00 32.32 N ANISOU 4771 N HIS E 432 4662 3283 4336 -499 617 -1934 N ATOM 4772 CA HIS E 432 34.063 -35.044 -23.091 1.00 34.03 C ANISOU 4772 CA HIS E 432 4877 3292 4760 -399 685 -2050 C ATOM 4773 CB HIS E 432 33.392 -36.424 -23.076 1.00 36.39 C ANISOU 4773 CB HIS E 432 5209 3369 5248 -441 649 -2222 C ATOM 4774 CG HIS E 432 32.433 -36.595 -21.940 1.00 38.68 C ANISOU 4774 CG HIS E 432 5527 3471 5699 -494 584 -2041 C ATOM 4775 ND1 HIS E 432 31.189 -35.998 -21.920 1.00 39.39 N ANISOU 4775 ND1 HIS E 432 5597 3668 5702 -607 513 -1936 N ATOM 4776 CE1 HIS E 432 30.584 -36.288 -20.782 1.00 39.89 C ANISOU 4776 CE1 HIS E 432 5675 3550 5932 -643 494 -1795 C ATOM 4777 NE2 HIS E 432 31.391 -37.043 -20.058 1.00 41.36 N ANISOU 4777 NE2 HIS E 432 5911 3505 6297 -559 536 -1776 N ATOM 4778 CD2 HIS E 432 32.561 -37.241 -20.754 1.00 40.10 C ANISOU 4778 CD2 HIS E 432 5748 3382 6107 -450 584 -1933 C ATOM 4779 C HIS E 432 35.358 -35.061 -23.901 1.00 35.10 C ANISOU 4779 C HIS E 432 4973 3565 4797 -332 791 -2220 C ATOM 4780 O HIS E 432 36.402 -35.469 -23.410 1.00 35.53 O ANISOU 4780 O HIS E 432 4993 3505 5002 -212 850 -2259 O ATOM 4781 N GLN E 433 35.258 -34.625 -25.152 1.00 35.90 N ANISOU 4781 N GLN E 433 5072 3931 4639 -414 811 -2323 N ATOM 4782 CA GLN E 433 36.394 -34.264 -25.999 1.00 36.69 C ANISOU 4782 CA GLN E 433 5128 4254 4558 -397 931 -2434 C ATOM 4783 CB GLN E 433 35.808 -33.686 -27.294 1.00 38.40 C ANISOU 4783 CB GLN E 433 5382 4764 4444 -531 907 -2469 C ATOM 4784 CG GLN E 433 36.487 -33.958 -28.567 1.00 42.26 C ANISOU 4784 CG GLN E 433 5849 5489 4720 -569 1019 -2729 C ATOM 4785 CD GLN E 433 36.743 -35.422 -28.835 1.00 46.49 C ANISOU 4785 CD GLN E 433 6351 5891 5423 -510 1069 -3088 C ATOM 4786 OE1 GLN E 433 37.885 -35.864 -28.762 1.00 46.73 O ANISOU 4786 OE1 GLN E 433 6307 5883 5565 -406 1191 -3246 O ATOM 4787 NE2 GLN E 433 35.701 -36.170 -29.196 1.00 49.59 N ANISOU 4787 NE2 GLN E 433 6786 6216 5839 -577 974 -3240 N ATOM 4788 C GLN E 433 37.266 -33.209 -25.278 1.00 33.83 C ANISOU 4788 C GLN E 433 4728 3932 4195 -345 981 -2204 C ATOM 4789 O GLN E 433 38.456 -33.403 -25.081 1.00 34.24 O ANISOU 4789 O GLN E 433 4705 3974 4330 -254 1077 -2284 O ATOM 4790 N LEU E 434 36.650 -32.110 -24.866 1.00 31.07 N ANISOU 4790 N LEU E 434 4418 3619 3768 -399 908 -1937 N ATOM 4791 CA LEU E 434 37.329 -31.034 -24.128 1.00 28.78 C ANISOU 4791 CA LEU E 434 4102 3346 3486 -372 939 -1719 C ATOM 4792 CB LEU E 434 36.367 -29.855 -23.924 1.00 26.01 C ANISOU 4792 CB LEU E 434 3811 3033 3038 -442 841 -1468 C ATOM 4793 CG LEU E 434 35.966 -29.145 -25.222 1.00 25.54 C ANISOU 4793 CG LEU E 434 3805 3209 2689 -551 822 -1442 C ATOM 4794 CD1 LEU E 434 34.729 -28.299 -25.018 1.00 24.35 C ANISOU 4794 CD1 LEU E 434 3706 3042 2504 -583 681 -1235 C ATOM 4795 CD2 LEU E 434 37.121 -28.319 -25.799 1.00 22.38 C ANISOU 4795 CD2 LEU E 434 3397 2995 2113 -602 943 -1400 C ATOM 4796 C LEU E 434 37.900 -31.483 -22.783 1.00 27.76 C ANISOU 4796 C LEU E 434 3927 2997 3622 -250 939 -1675 C ATOM 4797 O LEU E 434 39.014 -31.136 -22.430 1.00 27.07 O ANISOU 4797 O LEU E 434 3771 2946 3569 -196 1008 -1653 O ATOM 4798 N LEU E 435 37.110 -32.250 -22.042 1.00 27.99 N ANISOU 4798 N LEU E 435 3994 2811 3829 -220 856 -1657 N ATOM 4799 CA LEU E 435 37.487 -32.722 -20.719 1.00 27.82 C ANISOU 4799 CA LEU E 435 3960 2577 4035 -116 832 -1578 C ATOM 4800 CB LEU E 435 36.316 -33.464 -20.074 1.00 27.22 C ANISOU 4800 CB LEU E 435 3951 2294 4097 -145 746 -1530 C ATOM 4801 CG LEU E 435 36.445 -33.810 -18.591 1.00 28.04 C ANISOU 4801 CG LEU E 435 4075 2192 4388 -72 705 -1378 C ATOM 4802 CD1 LEU E 435 36.646 -32.562 -17.667 1.00 24.26 C ANISOU 4802 CD1 LEU E 435 3574 1799 3846 -69 694 -1159 C ATOM 4803 CD2 LEU E 435 35.226 -34.633 -18.191 1.00 25.93 C ANISOU 4803 CD2 LEU E 435 3877 1742 4232 -145 648 -1354 C ATOM 4804 C LEU E 435 38.771 -33.577 -20.768 1.00 29.75 C ANISOU 4804 C LEU E 435 4131 2762 4410 14 896 -1756 C ATOM 4805 O LEU E 435 39.778 -33.201 -20.144 1.00 28.71 O ANISOU 4805 O LEU E 435 3929 2650 4330 95 921 -1690 O ATOM 4806 N ARG E 436 38.741 -34.676 -21.534 1.00 32.34 N ANISOU 4806 N ARG E 436 4465 3030 4795 35 920 -1999 N ATOM 4807 CA ARG E 436 39.909 -35.546 -21.722 1.00 35.45 C ANISOU 4807 CA ARG E 436 4775 3363 5331 178 982 -2217 C ATOM 4808 CB ARG E 436 39.663 -36.647 -22.752 1.00 39.05 C ANISOU 4808 CB ARG E 436 5249 3770 5817 172 1014 -2522 C ATOM 4809 CG ARG E 436 38.505 -37.569 -22.494 1.00 44.53 C ANISOU 4809 CG ARG E 436 6055 4209 6656 124 920 -2530 C ATOM 4810 CD ARG E 436 38.611 -38.440 -21.233 1.00 52.12 C ANISOU 4810 CD ARG E 436 7061 4819 7923 242 842 -2421 C ATOM 4811 NE ARG E 436 37.245 -38.756 -20.802 1.00 57.30 N ANISOU 4811 NE ARG E 436 7831 5312 8631 112 760 -2299 N ATOM 4812 CZ ARG E 436 36.618 -38.200 -19.764 1.00 57.95 C ANISOU 4812 CZ ARG E 436 7958 5361 8701 53 702 -2012 C ATOM 4813 NH1 ARG E 436 37.239 -37.329 -18.967 1.00 55.93 N ANISOU 4813 NH1 ARG E 436 7660 5194 8395 119 701 -1810 N ATOM 4814 NH2 ARG E 436 35.361 -38.551 -19.498 1.00 60.15 N ANISOU 4814 NH2 ARG E 436 8312 5518 9024 -81 651 -1946 N ATOM 4815 C ARG E 436 41.160 -34.801 -22.148 1.00 35.22 C ANISOU 4815 C ARG E 436 4619 3580 5182 206 1094 -2273 C ATOM 4816 O ARG E 436 42.231 -35.071 -21.622 1.00 35.85 O ANISOU 4816 O ARG E 436 4598 3608 5416 348 1111 -2313 O ATOM 4817 N HIS E 437 41.028 -33.904 -23.128 1.00 34.80 N ANISOU 4817 N HIS E 437 4568 3798 4857 67 1165 -2278 N ATOM 4818 CA HIS E 437 42.118 -33.014 -23.525 1.00 34.74 C ANISOU 4818 CA HIS E 437 4454 4042 4705 38 1285 -2284 C ATOM 4819 CB HIS E 437 41.679 -32.053 -24.633 1.00 34.55 C ANISOU 4819 CB HIS E 437 4489 4283 4357 -146 1338 -2235 C ATOM 4820 CG HIS E 437 42.748 -31.068 -25.013 1.00 35.10 C ANISOU 4820 CG HIS E 437 4468 4599 4270 -217 1471 -2204 C ATOM 4821 ND1 HIS E 437 43.851 -31.420 -25.764 1.00 37.41 N ANISOU 4821 ND1 HIS E 437 4626 5075 4513 -200 1631 -2455 N ATOM 4822 CE1 HIS E 437 44.631 -30.366 -25.924 1.00 38.18 C ANISOU 4822 CE1 HIS E 437 4658 5375 4475 -302 1736 -2358 C ATOM 4823 NE2 HIS E 437 44.081 -29.345 -25.292 1.00 35.48 N ANISOU 4823 NE2 HIS E 437 4413 4960 4108 -374 1640 -2054 N ATOM 4824 CD2 HIS E 437 42.906 -29.759 -24.711 1.00 32.73 C ANISOU 4824 CD2 HIS E 437 4181 4382 3872 -313 1477 -1962 C ATOM 4825 C HIS E 437 42.749 -32.194 -22.375 1.00 33.02 C ANISOU 4825 C HIS E 437 4176 3799 4570 79 1259 -2066 C ATOM 4826 O HIS E 437 43.972 -32.101 -22.278 1.00 33.79 O ANISOU 4826 O HIS E 437 4129 3988 4720 145 1337 -2148 O ATOM 4827 N PHE E 438 41.926 -31.574 -21.532 1.00 31.16 N ANISOU 4827 N PHE E 438 4035 3462 4342 33 1153 -1812 N ATOM 4828 CA PHE E 438 42.449 -30.736 -20.445 1.00 29.88 C ANISOU 4828 CA PHE E 438 3826 3289 4236 53 1124 -1624 C ATOM 4829 CB PHE E 438 41.489 -29.603 -20.094 1.00 26.95 C ANISOU 4829 CB PHE E 438 3561 2923 3757 -63 1061 -1384 C ATOM 4830 CG PHE E 438 41.464 -28.502 -21.121 1.00 27.09 C ANISOU 4830 CG PHE E 438 3604 3149 3541 -212 1134 -1338 C ATOM 4831 CD1 PHE E 438 42.603 -27.741 -21.370 1.00 25.13 C ANISOU 4831 CD1 PHE E 438 3262 3064 3221 -267 1241 -1344 C ATOM 4832 CE1 PHE E 438 42.595 -26.732 -22.328 1.00 25.50 C ANISOU 4832 CE1 PHE E 438 3355 3289 3044 -424 1312 -1272 C ATOM 4833 CZ PHE E 438 41.445 -26.464 -23.056 1.00 25.46 C ANISOU 4833 CZ PHE E 438 3487 3307 2880 -504 1254 -1191 C ATOM 4834 CE2 PHE E 438 40.295 -27.218 -22.825 1.00 25.44 C ANISOU 4834 CE2 PHE E 438 3552 3162 2953 -438 1138 -1209 C ATOM 4835 CD2 PHE E 438 40.308 -28.232 -21.858 1.00 26.06 C ANISOU 4835 CD2 PHE E 438 3586 3055 3260 -305 1090 -1283 C ATOM 4836 C PHE E 438 42.892 -31.546 -19.216 1.00 30.99 C ANISOU 4836 C PHE E 438 3923 3228 4624 221 1042 -1610 C ATOM 4837 O PHE E 438 43.758 -31.116 -18.459 1.00 30.57 O ANISOU 4837 O PHE E 438 3776 3208 4631 274 1032 -1547 O ATOM 4838 N GLN E 439 42.333 -32.746 -19.058 1.00 32.94 N ANISOU 4838 N GLN E 439 4237 3267 5012 299 977 -1674 N ATOM 4839 CA GLN E 439 42.793 -33.691 -18.041 1.00 34.33 C ANISOU 4839 CA GLN E 439 4390 3229 5424 468 892 -1664 C ATOM 4840 CB GLN E 439 41.809 -34.835 -17.889 1.00 34.98 C ANISOU 4840 CB GLN E 439 4604 3055 5634 485 819 -1673 C ATOM 4841 CG GLN E 439 40.528 -34.421 -17.151 1.00 33.80 C ANISOU 4841 CG GLN E 439 4583 2832 5428 365 747 -1440 C ATOM 4842 CD GLN E 439 39.593 -35.607 -16.908 1.00 35.82 C ANISOU 4842 CD GLN E 439 4957 2826 5828 357 684 -1441 C ATOM 4843 OE1 GLN E 439 39.605 -36.585 -17.663 1.00 36.28 O ANISOU 4843 OE1 GLN E 439 5025 2780 5979 391 705 -1646 O ATOM 4844 NE2 GLN E 439 38.782 -35.521 -15.849 1.00 34.67 N ANISOU 4844 NE2 GLN E 439 4899 2575 5700 299 617 -1224 N ATOM 4845 C GLN E 439 44.181 -34.224 -18.355 1.00 36.88 C ANISOU 4845 C GLN E 439 4548 3601 5863 621 947 -1875 C ATOM 4846 O GLN E 439 44.947 -34.537 -17.454 1.00 38.31 O ANISOU 4846 O GLN E 439 4655 3695 6205 771 873 -1834 O ATOM 4847 N LYS E 440 44.506 -34.307 -19.639 1.00 38.67 N ANISOU 4847 N LYS E 440 4708 3989 5997 585 1074 -2109 N ATOM 4848 CA LYS E 440 45.830 -34.701 -20.085 1.00 41.00 C ANISOU 4848 CA LYS E 440 4811 4387 6378 713 1162 -2352 C ATOM 4849 CB LYS E 440 45.760 -35.237 -21.517 1.00 43.24 C ANISOU 4849 CB LYS E 440 5080 4772 6575 674 1289 -2647 C ATOM 4850 CG LYS E 440 44.974 -36.564 -21.628 1.00 44.39 C ANISOU 4850 CG LYS E 440 5348 4632 6884 748 1215 -2766 C ATOM 4851 CD LYS E 440 45.302 -37.362 -22.891 1.00 47.55 C ANISOU 4851 CD LYS E 440 5680 5105 7282 784 1335 -3147 C ATOM 4852 CE LYS E 440 44.512 -38.715 -22.929 1.00 50.57 C ANISOU 4852 CE LYS E 440 6192 5155 7866 848 1250 -3276 C ATOM 4853 NZ LYS E 440 45.145 -39.840 -23.728 1.00 54.88 N ANISOU 4853 NZ LYS E 440 6641 5641 8568 993 1329 -3685 N ATOM 4854 C LYS E 440 46.860 -33.566 -19.953 1.00 41.06 C ANISOU 4854 C LYS E 440 4658 4652 6290 666 1236 -2303 C ATOM 4855 O LYS E 440 48.025 -33.808 -19.611 1.00 42.57 O ANISOU 4855 O LYS E 440 4664 4881 6629 813 1240 -2407 O ATOM 4856 N ASP E 441 46.435 -32.336 -20.226 1.00 39.79 N ANISOU 4856 N ASP E 441 4560 4659 5898 463 1287 -2149 N ATOM 4857 CA ASP E 441 47.317 -31.180 -20.142 1.00 40.18 C ANISOU 4857 CA ASP E 441 4482 4932 5855 373 1365 -2091 C ATOM 4858 CB ASP E 441 48.154 -31.013 -21.419 1.00 43.33 C ANISOU 4858 CB ASP E 441 4737 5607 6118 295 1564 -2319 C ATOM 4859 CG ASP E 441 49.325 -30.041 -21.231 1.00 46.39 C ANISOU 4859 CG ASP E 441 4939 6211 6477 220 1653 -2302 C ATOM 4860 OD1 ASP E 441 49.448 -29.440 -20.140 1.00 48.49 O ANISOU 4860 OD1 ASP E 441 5197 6410 6818 225 1551 -2118 O ATOM 4861 OD2 ASP E 441 50.129 -29.879 -22.174 1.00 51.62 O

ANISOU 4861 OD2 ASP E 441 5456 7122 7035 143 1834 -2486 O

ATOM 4862 C ASP E 441 46.537 -29.904 -19.828 1.00 37.74 C ANISOU 4862 C ASP E 441 4310 4644 5386 194 1329 -1822 C ATOM 4863 O ASP E 441 45.864 -29.332 -20.693 1.00 37.25 O ANISOU 4863 O ASP E 441 4355 4675 5122 36 1387 -1775 O ATOM 4864 N ALA E 442 46.636 -29.476 -18.570 1.00 35.71 N ANISOU 4864 N ALA E 442 4047 4299 5223 231 1222 -1652 N ATOM 4865 CA ALA E 442 45.931 -28.299 -18.098 1.00 33.38 C ANISOU 4865 CA ALA E 442 3868 3993 4822 92 1177 -1423 C ATOM 4866 CB ALA E 442 45.419 -28.529 -16.675 1.00 31.22 C ANISOU 4866 CB ALA E 442 3665 3526 4672 185 1020 -1271 C ATOM 4867 C ALA E 442 46.776 -27.016 -18.181 1.00 33.32 C ANISOU 4867 C ALA E 442 3761 4170 4728 -46 1265 -1384 C ATOM 4868 O ALA E 442 46.260 -25.945 -17.903 1.00 32.99 O ANISOU 4868 O ALA E 442 3816 4112 4608 -168 1240 -1212 O ATOM 4869 N LYS E 443 48.043 -27.134 -18.584 1.00 34.87 N ANISOU 4869 N LYS E 443 3760 4535 4953 -31 1371 -1554 N ATOM 4870 CA LYS E 443 49.006 -26.014 -18.612 1.00 35.36 C ANISOU 4870 CA LYS E 443 3692 4779 4964 -175 1466 -1542 C ATOM 4871 CB LYS E 443 50.372 -26.455 -19.164 1.00 38.05 C ANISOU 4871 CB LYS E 443 3778 5324 5355 -134 1599 -1786 C ATOM 4872 CG LYS E 443 51.263 -27.243 -18.219 1.00 40.17 C ANISOU 4872 CG LYS E 443 3849 5559 5857 88 1500 -1903 C ATOM 4873 CD LYS E 443 52.487 -27.764 -18.987 1.00 43.53 C ANISOU 4873 CD LYS E 443 4010 6196 6334 144 1649 -2186 C ATOM 4874 CE LYS E 443 53.103 -28.956 -18.285 1.00 48.78 C ANISOU 4874 CE LYS E 443 4515 6765 7255 440 1522 -2328 C ATOM 4875 NZ LYS E 443 54.154 -29.631 -19.120 1.00 53.55 N ANISOU 4875 NZ LYS E 443 4860 7551 7935 536 1667 -2646 N ATOM 4876 C LYS E 443 48.554 -24.806 -19.413 1.00 33.77 C ANISOU 4876 C LYS E 443 3618 4659 4554 -414 1561 -1408 C ATOM 4877 O LYS E 443 48.684 -23.694 -18.948 1.00 33.32 O ANISOU 4877 O LYS E 443 3574 4600 4484 -537 1551 -1276 O ATOM 4878 N VAL E 444 48.057 -25.015 -20.627 1.00 33.39 N ANISOU 4878 N VAL E 444 3664 4680 4342 -482 1645 -1446 N ATOM 4879 CA VAL E 444 47.578 -23.901 -21.443 1.00 32.51 C ANISOU 4879 CA VAL E 444 3697 4640 4016 -699 1710 -1287 C ATOM 4880 CB VAL E 444 47.325 -24.320 -22.913 1.00 33.98 C ANISOU 4880 CB VAL E 444 3940 4981 3988 -767 1820 -1385 C ATOM 4881 CG1 VAL E 444 46.849 -23.117 -23.727 1.00 33.93 C ANISOU 4881 CG1 VAL E 444 4100 5048 3745 -989 1863 -1177 C ATOM 4882 CG2 VAL E 444 48.595 -24.935 -23.530 1.00 35.29 C ANISOU 4882 CG2 VAL E 444 3886 5374 4147 -757 1997 -1653 C ATOM 4883 C VAL E 444 46.325 -23.248 -20.824 1.00 30.69 C ANISOU 4883 C VAL E 444 3666 4204 3792 -710 1557 -1054 C ATOM 4884 O VAL E 444 46.204 -22.012 -20.791 1.00 30.76 O ANISOU 4884 O VAL E 444 3753 4195 3741 -856 1561 -883 O ATOM 4885 N LEU E 445 45.419 -24.090 -20.332 1.00 28.79 N ANISOU 4885 N LEU E 445 3497 3803 3639 -557 1429 -1058 N ATOM 4886 CA LEU E 445 44.175 -23.667 -19.699 1.00 27.40 C ANISOU 4886 CA LEU E 445 3476 3448 3487 -543 1291 -880 C ATOM 4887 CB LEU E 445 43.334 -24.905 -19.324 1.00 26.06 C ANISOU 4887 CB LEU E 445 3348 3141 3410 -390 1191 -938 C ATOM 4888 CG LEU E 445 42.005 -24.714 -18.603 1.00 24.67 C ANISOU 4888 CG LEU E 445 3297 2800 3277 -363 1061 -794 C ATOM 4889 CD1 LEU E 445 41.045 -23.943 -19.450 1.00 23.86 C ANISOU 4889 CD1 LEU E 445 3319 2724 3024 -467 1044 -683 C ATOM 4890 CD2 LEU E 445 41.388 -26.048 -18.167 1.00 23.79 C ANISOU 4890 CD2 LEU E 445 3204 2560 3276 -238 987 -863 C ATOM 4891 C LEU E 445 44.416 -22.841 -18.438 1.00 26.46 C ANISOU 4891 C LEU E 445 3330 3240 3486 -548 1230 -777 C ATOM 4892 O LEU E 445 43.801 -21.786 -18.261 1.00 26.04 O ANISOU 4892 O LEU E 445 3381 3112 3400 -630 1188 -624 O ATOM 4893 N PHE E 446 45.272 -23.353 -17.551 1.00 26.46 N ANISOU 4893 N PHE E 446 3188 3241 3625 -447 1211 -870 N ATOM 4894 CA PHE E 446 45.576 -22.697 -16.274 1.00 25.67 C ANISOU 4894 CA PHE E 446 3046 3084 3625 -444 1141 -806 C ATOM 4895 CB PHE E 446 46.347 -23.663 -15.363 1.00 26.39 C ANISOU 4895 CB PHE E 446 2995 3178 3856 -282 1079 -912 C ATOM 4896 CG PHE E 446 45.490 -24.679 -14.652 1.00 24.94 C ANISOU 4896 CG PHE E 446 2898 2839 3740 -131 959 -875 C ATOM 4897 CD1 PHE E 446 44.152 -24.830 -14.944 1.00 24.46 C ANISOU 4897 CD1 PHE E 446 2999 2671 3625 -146 932 -796 C ATOM 4898 CE1 PHE E 446 43.370 -25.769 -14.271 1.00 25.96 C ANISOU 4898 CE1 PHE E 446 3262 2721 3881 -40 838 -760 C ATOM 4899 CZ PHE E 446 43.927 -26.577 -13.306 1.00 26.29 C ANISOU 4899 CZ PHE E 446 3242 2714 4034 92 761 -778 C ATOM 4900 CE2 PHE E 446 45.274 -26.429 -12.996 1.00 28.95 C ANISOU 4900 CE2 PHE E 446 3418 3158 4423 134 764 -850 C ATOM 4901 CD2 PHE E 446 46.045 -25.494 -13.676 1.00 27.06 C ANISOU 4901 CD2 PHE E 446 3080 3073 4128 20 868 -912 C ATOM 4902 C PHE E 446 46.389 -21.403 -16.496 1.00 26.52 C ANISOU 4902 C PHE E 446 3097 3289 3693 -623 1230 -777 C ATOM 4903 O PHE E 446 46.081 -20.387 -15.902 1.00 26.04 O ANISOU 4903 O PHE E 446 3101 3142 3650 -697 1185 -672 O ATOM 4904 N GLN E 447 47.407 -21.441 -17.364 1.00 28.42 N ANISOU 4904 N GLN E 447 3213 3703 3882 -703 1367 -882 N ATOM 4905 CA GLN E 447 48.255 -20.272 -17.631 1.00 30.21 C ANISOU 4905 CA GLN E 447 3374 4031 4073 -906 1474 -858 C ATOM 4906 CB GLN E 447 49.558 -20.665 -18.370 1.00 32.70 C ANISOU 4906 CB GLN E 447 3479 4581 4365 -956 1632 -1034 C ATOM 4907 CG GLN E 447 50.469 -21.664 -17.619 1.00 33.25 C ANISOU 4907 CG GLN E 447 3317 4717 4599 -768 1585 -1223 C ATOM 4908 CD GLN E 447 51.134 -21.082 -16.361 1.00 34.07 C ANISOU 4908 CD GLN E 447 3297 4813 4836 -777 1499 -1223 C ATOM 4909 OE1 GLN E 447 50.681 -20.084 -15.801 1.00 33.58 O ANISOU 4909 OE1 GLN E 447 3351 4637 4770 -881 1442 -1088 O ATOM 4910 NE2 GLN E 447 52.215 -21.716 -15.914 1.00 33.89 N ANISOU 4910 NE2 GLN E 447 3028 4913 4937 -660 1480 -1391 N ATOM 4911 C GLN E 447 47.535 -19.110 -18.348 1.00 30.32 C ANISOU 4911 C GLN E 447 3585 3978 3959 -1087 1508 -671 C ATOM 4912 O GLN E 447 47.924 -17.962 -18.215 1.00 31.49 O ANISOU 4912 O GLN E 447 3740 4105 4121 -1252 1546 -595 O ATOM 4913 N ASN E 448 46.468 -19.409 -19.073 1.00 30.31 N ANISOU 4913 N ASN E 448 3744 3928 3845 -1051 1477 -595 N ATOM 4914 CA ASN E 448 45.761 -18.409 -19.873 1.00 30.88 C ANISOU 4914 CA ASN E 448 4004 3947 3783 -1195 1485 -407 C ATOM 4915 CB ASN E 448 45.584 -18.920 -21.309 1.00 32.53 C ANISOU 4915 CB ASN E 448 4268 4311 3782 -1240 1569 -424 C ATOM 4916 CG ASN E 448 46.858 -18.826 -22.104 1.00 35.40 C ANISOU 4916 CG ASN E 448 4506 4905 4040 -1401 1764 -514 C ATOM 4917 OD1 ASN E 448 47.280 -17.741 -22.458 1.00 39.32 O ANISOU 4917 OD1 ASN E 448 5044 5427 4468 -1605 1846 -389 O ATOM 4918 ND2 ASN E 448 47.482 -19.960 -22.378 1.00 37.31 N ANISOU 4918 ND2 ASN E 448 4588 5308 4280 -1312 1845 -737 N ATOM 4919 C ASN E 448 44.419 -17.982 -19.291 1.00 29.13 C ANISOU 4919 C ASN E 448 3941 3507 3618 -1115 1326 -267 C ATOM 4920 O ASN E 448 43.766 -17.081 -19.821 1.00 29.93 O ANISOU 4920 O ASN E 448 4198 3528 3646 -1201 1297 -98 O ATOM 4921 N TRP E 449 44.039 -18.593 -18.176 1.00 27.59 N ANISOU 4921 N TRP E 449 3703 3222 3558 -952 1225 -333 N ATOM 4922 CA TRP E 449 42.729 -18.370 -17.542 1.00 26.76 C ANISOU 4922 CA TRP E 449 3713 2942 3513 -861 1090 -243 C ATOM 4923 CB TRP E 449 42.475 -19.424 -16.454 1.00 24.28 C ANISOU 4923 CB TRP E 449 3331 2590 3304 -695 1016 -340 C ATOM 4924 CG TRP E 449 41.137 -19.316 -15.787 1.00 23.02 C ANISOU 4924 CG TRP E 449 3262 2290 3195 -614 905 -273 C ATOM 4925 CD1 TRP E 449 40.863 -18.715 -14.596 1.00 21.45 C ANISOU 4925 CD1 TRP E 449 3066 1994 3092 -591 847 -256 C ATOM 4926 NE1 TRP E 449 39.515 -18.822 -14.298 1.00 20.39 N ANISOU 4926 NE1 TRP E 449 3000 1770 2976 -516 770 -215 N ATOM 4927 CE2 TRP E 449 38.885 -19.504 -15.306 1.00 21.49 C ANISOU 4927 CE2 TRP E 449 3183 1943 3039 -494 763 -200 C ATOM 4928 CD2 TRP E 449 39.876 -19.846 -16.270 1.00 24.86 C ANISOU 4928 CD2 TRP E 449 3576 2486 3383 -553 846 -240 C ATOM 4929 CE3 TRP E 449 39.491 -20.568 -17.422 1.00 23.76 C ANISOU 4929 CE3 TRP E 449 3472 2418 3138 -550 858 -261 C ATOM 4930 CZ3 TRP E 449 38.128 -20.936 -17.561 1.00 23.43 C ANISOU 4930 CZ3 TRP E 449 3491 2323 3088 -492 771 -235 C ATOM 4931 CH2 TRP E 449 37.172 -20.568 -16.574 1.00 21.37 C ANISOU 4931 CH2 TRP E 449 3244 1947 2927 -437 692 -188 C ATOM 4932 CZ2 TRP E 449 37.535 -19.864 -15.450 1.00 20.61 C ANISOU 4932 CZ2 TRP E 449 3121 1786 2923 -435 694 -175 C ATOM 4933 C TRP E 449 42.490 -16.955 -16.983 1.00 27.51 C ANISOU 4933 C TRP E 449 3882 2888 3683 -936 1047 -131 C ATOM 4934 O TRP E 449 41.353 -16.459 -16.959 1.00 28.76 O ANISOU 4934 O TRP E 449 4157 2914 3855 -897 959 -29 O ATOM 4935 N GLY E 450 43.527 -16.296 -16.504 1.00 28.21 N ANISOU 4935 N GLY E 450 3890 2989 3838 -1037 1102 -166 N ATOM 4936 CA GLY E 450 43.293 -14.993 -15.886 1.00 27.79 C ANISOU 4936 CA GLY E 450 3907 2766 3884 -1103 1057 -93 C ATOM 4937 C GLY E 450 43.612 -15.062 -14.403 1.00 26.81 C ANISOU 4937 C GLY E 450 3678 2623 3885 -1038 1007 -216 C ATOM 4938 O GLY E 450 43.219 -16.005 -13.720 1.00 25.75 O ANISOU 4938 O GLY E 450 3501 2518 3763 -889 946 -282 O ATOM 4939 N ILE E 451 44.331 -14.049 -13.925 1.00 27.46 N ANISOU 4939 N ILE E 451 3725 2659 4049 -1166 1031 -243 N ATOM 4940 CA ILE E 451 44.805 -13.944 -12.563 1.00 26.27 C ANISOU 4940 CA ILE E 451 3467 2521 3994 -1141 984 -372 C ATOM 4941 CB ILE E 451 46.380 -13.916 -12.516 1.00 27.56 C ANISOU 4941 CB ILE E 451 3449 2845 4177 -1267 1061 -479 C ATOM 4942 CG1 ILE E 451 46.919 -14.436 -11.178 1.00 27.57 C ANISOU 4942 CG1 ILE E 451 3300 2949 4228 -1173 981 -627 C ATOM 4943 CD1 ILE E 451 47.068 -15.951 -11.141 1.00 22.34 C ANISOU 4943 CD1 ILE E 451 2547 2426 3515 -998 952 -669 C ATOM 4944 CG2 ILE E 451 46.958 -12.547 -12.840 1.00 28.46 C ANISOU 4944 CG2 ILE E 451 3590 2876 4349 -1500 1134 -445 C ATOM 4945 C ILE E 451 44.170 -12.690 -11.957 1.00 26.81 C ANISOU 4945 C ILE E 451 3641 2382 4162 -1182 931 -349 C ATOM 4946 O ILE E 451 43.942 -11.712 -12.669 1.00 27.27 O ANISOU 4946 O ILE E 451 3818 2296 4248 -1289 957 -238 O ATOM 4947 N GLU E 452 43.846 -12.740 -10.657 1.00 26.34 N ANISOU 4947 N GLU E 452 3548 2306 4155 -1090 853 -453 N ATOM 4948 CA GLU E 452 43.223 -11.616 -9.949 1.00 27.25 C ANISOU 4948 CA GLU E 452 3743 2237 4375 -1105 806 -486 C ATOM 4949 CB GLU E 452 41.711 -11.797 -9.805 1.00 26.07 C ANISOU 4949 CB GLU E 452 3691 1990 4224 -947 745 -441 C ATOM 4950 CG GLU E 452 41.266 -12.939 -8.853 1.00 25.31 C ANISOU 4950 CG GLU E 452 3530 2030 4058 -801 701 -515 C ATOM 4951 CD GLU E 452 39.756 -13.124 -8.803 1.00 24.53 C ANISOU 4951 CD GLU E 452 3504 1856 3961 -674 661 -476 C ATOM 4952 OE1 GLU E 452 39.068 -12.217 -9.314 1.00 25.81 O ANISOU 4952 OE1 GLU E 452 3753 1850 4202 -676 647 -420 O ATOM 4953 OE2 GLU E 452 39.251 -14.177 -8.283 1.00 23.51 O ANISOU 4953 OE2 GLU E 452 3341 1829 3761 -574 642 -494 O ATOM 4954 C GLU E 452 43.848 -11.432 -8.580 1.00 28.43 C ANISOU 4954 C GLU E 452 3783 2458 4563 -1127 771 -662 C ATOM 4955 O GLU E 452 44.286 -12.399 -7.949 1.00 27.98 O ANISOU 4955 O GLU E 452 3614 2584 4434 -1053 740 -731 O ATOM 4956 N HIS E 453 43.923 -10.180 -8.146 1.00 30.69 N ANISOU 4956 N HIS E 453 4104 2592 4964 -1232 766 -734 N ATOM 4957 CA HIS E 453 44.200 -9.865 -6.747 1.00 32.45 C ANISOU 4957 CA HIS E 453 4251 2864 5216 -1241 715 -926 C ATOM 4958 CB HIS E 453 44.444 -8.372 -6.528 1.00 34.20 C ANISOU 4958 CB HIS E 453 4517 2885 5593 -1398 727 -1017 C ATOM 4959 CG HIS E 453 45.250 -8.092 -5.296 1.00 39.68 C ANISOU 4959 CG HIS E 453 5086 3695 6296 -1476 688 -1238 C ATOM 4960 ND1 HIS E 453 44.724 -7.482 -4.169 1.00 43.34 N ANISOU 4960 ND1 HIS E 453 5574 4092 6801 -1445 640 -1415 N ATOM 4961 CE1 HIS E 453 45.664 -7.391 -3.246 1.00 44.55 C ANISOU 4961 CE1 HIS E 453 5596 4407 6924 -1535 601 -1598 C ATOM 4962 NE2 HIS E 453 46.769 -7.945 -3.718 1.00 42.51 N ANISOU 4962 NE2 HIS E 453 5213 4316 6621 -1609 617 -1544 N ATOM 4963 CD2 HIS E 453 46.540 -8.383 -4.997 1.00 40.32 C ANISOU 4963 CD2 HIS E 453 5000 3982 6338 -1576 682 -1329 C ATOM 4964 C HIS E 453 43.055 -10.310 -5.860 1.00 31.39 C ANISOU 4964 C HIS E 453 4153 2749 5027 -1069 658 -973 C ATOM 4965 O HIS E 453 41.890 -10.357 -6.286 1.00 30.46 O ANISOU 4965 O HIS E 453 4134 2517 4921 -967 656 -882 O ATOM 4966 N ILE E 454 43.380 -10.638 -4.618 1.00 31.87 N ANISOU 4966 N ILE E 454 4122 2971 5015 -1043 609 -1116 N ATOM 4967 CA ILE E 454 42.346 -11.093 -3.700 1.00 31.42 C ANISOU 4967 CA ILE E 454 4094 2967 4875 -909 573 -1161 C ATOM 4968 CB ILE E 454 42.380 -12.627 -3.506 1.00 30.33 C ANISOU 4968 CB ILE E 454 3911 3030 4585 -798 542 -1074 C ATOM 4969 CG1 ILE E 454 43.610 -13.057 -2.681 1.00 31.20 C ANISOU 4969 CG1 ILE E 454 3893 3350 4610 -830 478 -1157 C ATOM 4970 CD1 ILE E 454 43.581 -14.534 -2.282 1.00 29.25 C ANISOU 4970 CD1 ILE E 454 3622 3268 4225 -703 423 -1067 C ATOM 4971 CG2 ILE E 454 42.334 -13.309 -4.878 1.00 29.40 C ANISOU 4971 CG2 ILE E 454 3820 2871 4478 -764 580 -902 C ATOM 4972 C ILE E 454 42.322 -10.396 -2.359 1.00 32.96 C ANISOU 4972 C ILE E 454 4262 3196 5064 -942 541 -1372 C ATOM 4973 O ILE E 454 43.289 -9.765 -1.929 1.00 34.56 O ANISOU 4973 O ILE E 454 4398 3432 5303 -1065 521 -1505 O ATOM 4974 N ASP E 455 41.171 -10.489 -1.720 1.00 33.18 N ANISOU 4974 N ASP E 455 4337 3225 5046 -841 545 -1419 N ATOM 4975 CA ASP E 455 41.040 -10.071 -0.349 1.00 34.92 C ANISOU 4975 CA ASP E 455 4527 3541 5200 -856 525 -1632 C ATOM 4976 CB ASP E 455 39.607 -9.614 -0.072 1.00 35.97 C ANISOU 4976 CB ASP E 455 4721 3562 5384 -767 570 -1709 C ATOM 4977 CG ASP E 455 39.150 -8.513 -1.016 1.00 38.40 C ANISOU 4977 CG ASP E 455 5103 3558 5931 -768 596 -1692 C ATOM 4978 OD1 ASP E 455 39.930 -7.575 -1.295 1.00 43.88 O ANISOU 4978 OD1 ASP E 455 5809 4103 6759 -885 588 -1746 O ATOM 4979 OD2 ASP E 455 38.012 -8.581 -1.493 1.00 39.86 O ANISOU 4979 OD2 ASP E 455 5332 3641 6173 -656 616 -1617 O ATOM 4980 C ASP E 455 41.428 -11.210 0.583 1.00 34.38 C ANISOU 4980 C ASP E 455 4395 3761 4905 -821 470 -1620 C ATOM 4981 O ASP E 455 41.239 -12.372 0.267 1.00 33.22 O ANISOU 4981 O ASP E 455 4259 3693 4672 -739 463 -1447 O ATOM 4982 N ASN E 456 42.001 -10.857 1.727 1.00 36.29 N ANISOU 4982 N ASN E 456 4579 4155 5054 -888 421 -1805 N ATOM 4983 CA ASN E 456 42.242 -11.804 2.805 1.00 36.41 C ANISOU 4983 CA ASN E 456 4556 4451 4827 -852 350 -1799 C ATOM 4984 CB ASN E 456 43.157 -11.172 3.870 1.00 38.96 C ANISOU 4984 CB ASN E 456 4797 4935 5071 -959 274 -2023 C ATOM 4985 CG ASN E 456 44.549 -10.827 3.334 1.00 40.45 C ANISOU 4985 CG ASN E 456 4881 5107 5382 -1060 220 -2046 C ATOM 4986 OD1 ASN E 456 45.178 -11.638 2.635 1.00 41.16 O ANISOU 4986 OD1 ASN E 456 4920 5233 5486 -1020 191 -1874 O ATOM 4987 ND2 ASN E 456 45.040 -9.624 3.669 1.00 39.97 N ANISOU 4987 ND2 ASN E 456 4777 4994 5418 -1199 215 -2279 N ATOM 4988 C ASN E 456 40.922 -12.229 3.444 1.00 35.91 C ANISOU 4988 C ASN E 456 4561 4451 4631 -773 404 -1790 C ATOM 4989 O ASN E 456 40.246 -11.425 4.099 1.00 37.52 O ANISOU 4989 O ASN E 456 4782 4643 4833 -794 455 -1984 O ATOM 4990 N VAL E 457 40.543 -13.483 3.230 1.00 33.98 N ANISOU 4990 N VAL E 457 4351 4269 4291 -689 402 -1578 N ATOM 4991 CA VAL E 457 39.365 -14.080 3.867 1.00 33.82 C ANISOU 4991 CA VAL E 457 4385 4343 4122 -641 458 -1541 C ATOM 4992 CB VAL E 457 38.259 -14.476 2.836 1.00 32.61 C ANISOU 4992 CB VAL E 457 4279 4018 4093 -568 540 -1399 C ATOM 4993 CG1 VAL E 457 37.029 -15.057 3.553 1.00 32.25 C ANISOU 4993 CG1 VAL E 457 4264 4088 3900 -547 614 -1383 C ATOM 4994 CG2 VAL E 457 37.839 -13.264 1.956 1.00 34.28 C ANISOU 4994 CG2 VAL E 457 4492 3983 4548 -564 592 -1495 C ATOM 4995 C VAL E 457 39.833 -15.326 4.626 1.00 33.51 C ANISOU 4995 C VAL E 457 4356 4530 3847 -623 373 -1398 C ATOM 4996 O VAL E 457 40.368 -16.254 4.027 1.00 32.47 O ANISOU 4996 O VAL E 457 4224 4372 3741 -570 314 -1210 O ATOM 4997 N MSE E 458 39.663 -15.333 5.946 1.00 34.54 N ANISOU 4997 N MSE E 458 4498 4881 3746 -664 361 -1491 N ATOM 4998 CA MSE E 458 40.077 -16.485 6.758 1.00 34.73 C ANISOU 4998 CA MSE E 458 4554 5121 3522 -649 262 -1328 C ATOM 4999 CB MSE E 458 39.930 -16.198 8.270 1.00 36.83 C ANISOU 4999 CB MSE E 458 4834 5661 3500 -725 252 -1475 C ATOM 5000 CG MSE E 458 40.556 -17.267 9.149 1.00 36.65 C ANISOU 5000 CG MSE E 458 4852 5870 3203 -714 109 -1293 C ATOM 5001 SE MSE E 458 40.273 -16.954 11.015 0.90 41.76 SE ANISOU 5001 SE MSE E 458 5537 6903 3425 -827 106 -1458 SE ATOM 5002 CE MSE E 458 41.315 -18.332 11.797 1.00 45.02 C ANISOU 5002 CE MSE E 458 6009 7547 3550 -781 -137 -1152 C ATOM 5003 C MSE E 458 39.307 -17.753 6.367 1.00 33.55 C ANISOU 5003 C MSE E 458 4487 4909 3352 -591 305 -1072 C ATOM 5004 O MSE E 458 38.099 -17.701 6.110 1.00 32.64 O ANISOU 5004 O MSE E 458 4404 4712 3286 -596 437 -1080 O ATOM 5005 N GLY E 459 40.010 -18.883 6.316 1.00 33.52 N ANISOU 5005 N GLY E 459 4507 4934 3293 -532 189 -859 N ATOM 5006 CA GLY E 459 39.389 -20.156 5.923 1.00 33.09 C ANISOU 5006 CA GLY E 459 4540 4788 3245 -484 216 -617 C ATOM 5007 C GLY E 459 39.465 -20.494 4.445 1.00 31.02 C ANISOU 5007 C GLY E 459 4259 4286 3242 -413 236 -537 C ATOM 5008 O GLY E 459 38.878 -21.472 4.003 1.00 29.76 O ANISOU 5008 O GLY E 459 4166 4024 3119 -382 269 -374 O ATOM 5009 N MSE E 460 40.234 -19.707 3.697 1.00 31.09 N ANISOU 5009 N MSE E 460 4178 4216 3419 -401 216 -654 N ATOM 5010 CA MSE E 460 40.276 -19.773 2.235 1.00 31.27 C ANISOU 5010 CA MSE E 460 4178 4037 3665 -358 258 -615 C ATOM 5011 CB MSE E 460 39.161 -18.884 1.732 1.00 30.55 C ANISOU 5011 CB MSE E 460 4104 3830 3674 -400 385 -715 C ATOM 5012 CG MSE E 460 38.666 -19.120 0.368 1.00 31.73 C ANISOU 5012 CG MSE E 460 4270 3798 3987 -364 442 -641 C ATOM 5013 SE MSE E 460 37.264 -17.775 0.139 0.90 36.29 SE ANISOU 5013 SE MSE E 460 4850 4272 4665 -398 558 -792 SE ATOM 5014 CE MSE E 460 35.900 -18.531 1.319 1.00 33.17 C ANISOU 5014 CE MSE E 460 4495 4021 4089 -418 629 -764 C ATOM 5015 C MSE E 460 41.595 -19.181 1.740 1.00 29.41 C ANISOU 5015 C MSE E 460 3836 3797 3541 -360 197 -704 C ATOM 5016 O MSE E 460 42.123 -18.243 2.345 1.00 30.18 O ANISOU 5016 O MSE E 460 3874 3990 3604 -424 166 -859 O ATOM 5017 N VAL E 461 42.129 -19.739 0.654 1.00 27.19 N ANISOU 5017 N VAL E 461 3522 3418 3392 -302 187 -625 N ATOM 5018 CA VAL E 461 43.328 -19.186 0.002 1.00 26.63 C ANISOU 5018 CA VAL E 461 3332 3346 3439 -324 164 -711 C ATOM 5019 CB VAL E 461 44.678 -19.981 0.317 1.00 27.57 C ANISOU 5019 CB VAL E 461 3343 3596 3535 -245.

26. 678 C ATOM 5020 CG1 VAL E 461 45.146 -19.726 1.712 1.00 30.38 C ANISOU 5020 CG1 VAL E 461 3661 4147 3734 -267 -90 -741 C ATOM 5021 CG2 VAL E 461 44.544 -21.476 0.054 1.00 27.15 C ANISOU 5021 CG2 VAL E 461 3343 3486 3488 -113 -505 C ATOM 5022 C VAL E 461 43.155 -19.117 -1.507 1.00 24.12 C ANISOU 5022 C VAL E 461 3020 2866 3278 -326 258 -681 C ATOM 5023 O VAL E 461 42.324 -19.841 -2.080 1.00 22.67 O ANISOU 5023 O VAL E 461 2916 2584 3112 -275 303 -577 O ATOM 5024 N GLY E 462 43.947 -18.249 -2.140 1.00 23.16 N ANISOU 5024 N GLY E 462 2816 2728 3258 -401 288 -772 N ATOM 5025 CA GLY E 462 44.112 -18.282 -3.598 1.00 21.82 C ANISOU 5025 CA GLY E 462 2635 2456 3200 -412 367 -733 C ATOM 5026 C GLY E 462 44.981 -19.456 -4.067 1.00 21.42 C ANISOU 5026 C GLY E 462 2500 2467 3173 -317 329 -687 C ATOM 5027 O GLY E 462 45.717 -20.046 -3.299 1.00 20.90 O ANISOU 5027 O GLY E 462 2354 2517 3068 -248 226 -695 O ATOM 5028 N VAL E 463 44.888 -19.781 -5.350 1.00 21.09 N ANISOU 5028 N VAL E 463 2471 2348 3194 -308 408 -648 N ATOM 5029 CA VAL E 463 45.725 -20.807 -5.947 1.00 20.88 C ANISOU 5029 CA VAL E 463 2351 2370 3213 -218 396 -648 C ATOM 5030 CB VAL E 463 44.939 -22.151 -6.066 1.00 21.07 C ANISOU 5030 CB VAL E 463 2475 2306 3226 -91 372 -548 C ATOM 5031 CG1 VAL E 463 43.726 -22.012 -7.015 1.00 18.51 C ANISOU 5031 CG1 VAL E 463 2276 1857 2899 -139 466 -501 C ATOM 5032 CG2 VAL E 463 45.863 -23.303 -6.490 1.00 19.87 C ANISOU 5032 CG2 VAL E 463 2221 2184 3145 35 338 -572 C ATOM 5033 C VAL E 463 46.254 -20.270 -7.294 1.00 20.93 C ANISOU 5033 C VAL E 463 2297 2378 3279 -312 513 -699 C ATOM 5034 O VAL E 463 45.503 -19.667 -8.067 1.00 20.04 O ANISOU 5034 O VAL E 463 2287 2170 3159 -394 595 -659 O ATOM 5035 N LEU E 464 47.555 -20.432 -7.522 1.00 21.97 N ANISOU 5035 N LEU E 464 2253 2633 3461 -308 516 -787 N ATOM 5036 CA LEU E 464 48.217 -20.037 -8.768 1.00 22.38 C ANISOU 5036 CA LEU E 464 2222 2733 3549 -412 644 -844 C ATOM 5037 CB LEU E 464 49.692 -19.686 -8.481 1.00 23.67 C ANISOU 5037 CB LEU E 464 2157 3066 3770 -468 634 -973 C ATOM 5038 CG LEU E 464 50.020 -18.579 -7.451 1.00 24.00 C ANISOU 5038 CG LEU E 464 2156 3149 3816 -587 574 -1026 C ATOM 5039 CD1 LEU E 464 51.527 -18.280 -7.395 1.00 23.87 C ANISOU 5039 CD1 LEU E 464 1881 3320 3868 -665 578 -1172 C ATOM 5040 CD2 LEU E 464 49.204 -17.298 -7.711 1.00 19.83 C ANISOU 5040 CD2 LEU E 464 1791 2471 3272 -757 652 -975 C ATOM 5041 C LEU E 464 48.096 -21.191 -9.796 1.00 23.25 C ANISOU 5041 C LEU E 464 2340 2827 3666 -306 696 -838 C ATOM 5042 O LEU E 464 47.759 -22.317 -9.404 1.00 23.03 O ANISOU 5042 O LEU E 464 2348 2749 3651 -145 614 -807 O ATOM 5043 N PRO E 465 48.325 -20.915 -11.110 1.00 24.19 N ANISOU 5043 N PRO E 465 2442 2983 3768 -407 835 -868 N ATOM 5044 CA PRO E 465 48.340 -21.987 -12.127 1.00 25.02 C ANISOU 5044 CA PRO E 465 2532 3105 3868 -317 897 -912 C ATOM 5045 CB PRO E 465 48.816 -21.267 -13.393 1.00 25.21 C ANISOU 5045 CB PRO E 465 2515 3230 3834 -493 1061 -949 C ATOM 5046 CG PRO E 465 48.349 -19.856 -13.215 1.00 25.13 C ANISOU 5046 CG PRO E 465 2621 3143 3785 -666 1072 -842 C ATOM 5047 CD PRO E 465 48.511 -19.577 -11.724 1.00 25.08 C ANISOU 5047 CD PRO E 465 2570 3111 3849 -623 944 -853 C ATOM 5048 C PRO E 465 49.235 -23.225 -11.820 1.00 27.35 C ANISOU 5048 C PRO E 465 2659 3471 4261 -129 835 -1023 C ATOM 5049 O PRO E 465 48.830 -24.361 -12.130 1.00 26.54 O ANISOU 5049 O PRO E 465 2609 3290 4185 9 814 -1032 O ATOM 5050 N ASP E 466 50.418 -23.018 -11.230 1.00 29.43 N ANISOU 5050 N ASP E 466 2720 3869 4592 -119 795 -1113 N ATOM 5051 CA ASP E 466 51.243 -24.148 -10.769 1.00 32.32 C ANISOU 5051 CA ASP E 466 2921 4288 5071 93 692 -1202 C ATOM 5052 CB ASP E 466 52.739 -23.769 -10.621 1.00 34.50 C ANISOU 5052 CB ASP E 466 2906 4779 5422 65 702 -1353 C ATOM 5053 CG ASP E 466 53.011 -22.725 -9.515 1.00 36.86 C ANISOU 5053 CG ASP E 466 3166 5140 5698 -48 612 -1323 C ATOM 5054 OD1 ASP E 466 52.104 -22.374 -8.726 1.00 36.45 O ANISOU 5054 OD1 ASP E 466 3303 4971 5575 -73 529 -1195 O ATOM 5055 OD2 ASP E 466 54.164 -22.236 -9.438 1.00 40.79 O ANISOU 5055 OD2 ASP E 466 3426 5820 6251 -123 630 -1452 O ATOM 5056 C ASP E 466 50.683 -24.859 -9.498 1.00 32.48 C ANISOU 5056 C ASP E 466 3053 4182 5108 257 499 -1082 C ATOM 5057 O ASP E 466 51.316 -25.787 -8.955 1.00 34.03 O ANISOU 5057 O ASP E 466 3140 4392 5398 449 373 -1114 O ATOM 5058 N MSE E 467 49.498 -24.434 -9.038 1.00 30.80 N ANISOU 5058 N MSE E 467 3052 3848 4801 183 475 -942 N ATOM 5059 CA MSE E 467 48.846 -25.020 -7.854 1.00 30.56 C ANISOU 5059 CA MSE E 467 3147 3717 4746 291 324 -814 C ATOM 5060 CB MSE E 467 48.762 -26.561 -7.943 1.00 31.92 C ANISOU 5060 CB MSE E 467 3352 3770 5007 491 255 -788 C ATOM 5061 CG MSE E 467 47.737 -27.121 -8.964 1.00 31.71 C ANISOU 5061 CG MSE E 467 3477 3592 4981 477 356 -771 C ATOM 5062 SE MSE E 467 45.883 -26.433 -8.795 0.90 34.47 SE ANISOU 5062 SE MSE E 467 4082 3825 5191 312 402 -618 SE ATOM 5063 CE MSE E 467 45.524 -26.906 -6.992 1.00 31.60 C ANISOU 5063 CE MSE E 467 3808 3411 4787 390 232 -460 C ATOM 5064 C MSE E 467 49.441 -24.599 -6.507 1.00 31.54 C ANISOU 5064 C MSE E 467 3189 3953 4840 301 184 -803 C ATOM 5065 O MSE E 467 49.044 -25.120 -5.466 1.00 31.93 O ANISOU 5065 O MSE E 467 3332 3957 4844 38.

53. 692 O ATOM 5066 N THR E 468 50.376 -23.644 -6.523 1.00 32.10 N ANISOU 5066 N THR E 468 3090 4182 4925 193 214 -918 N ATOM 5067 CA THR E 468 50.923 -23.058 -5.298 1.00 32.25 C ANISOU 5067 CA THR E 468 3023 4330 4900 16.

86. 940 C ATOM 5068 CB THR E 468 52.209 -22.245 -5.586 1.00 33.45 C ANISOU 5068 CB THR E 468 2925 4665 5118 52 132 -1109 C ATOM 5069 OG1 THR E 468 53.248 -23.146 -5.974 1.00 36.74 O ANISOU 5069 OG1 THR E 468 3131 5176 5652 20.

99. 1199 O ATOM 5070 CG2 THR E 468 52.708 -21.493 -4.365 1.00 35.62 C ANISOU 5070 CG2 THR E 468 3114 5077 5342 -16.

5. 1160 C ATOM 5071 C THR E 468 49.829 -22.192 -4.665 1.00 30.54 C ANISOU 5071 C THR E 468 2997 4041 4564 3.

99. 864 C ATOM 5072 O THR E 468 49.160 -21.413 -5.371 1.00 28.58 O ANISOU 5072 O THR E 468 2848 3706 4305 -106 236 -861 O ATOM 5073 N PRO E 469 49.621 -22.346 -3.345 1.00 30.70 N ANISOU 5073 N PRO E 469 3072 4103 449.

85. 46 -802 N ATOM 5074 CA PRO E 469 48.656 -21.488 -2.669 1.00 30.08 C ANISOU 5074 CA PRO E 469 3144 3989 4298 -36 -24 -774 C ATOM 5075 CB PRO E 469 48.508 -22.138 -1.284 1.00 31.30 C ANISOU 5075 CB PRO E 469 3355 4213 432.

65. 191 -683 C ATOM 5076 CG PRO E 469 49.779 -22.851 -1.077 1.00 33.03 C ANISOU 5076 CG PRO E 469 3396 4554 4601 203 -334 -705 C ATOM 5077 CD PRO E 469 50.246 -23.308 -2.421 1.00 32.56 C ANISOU 5077 CD PRO E 469 3238 4425 4708 260 -238 -754 C ATOM 5078 C PRO E 469 49.205 -20.071 -2.547 1.00 30.36 C ANISOU 5078 C PRO E 469 3079 4112 4345 -212.

15. 921 C ATOM 5079 O PRO E 469 50.414 -19.874 -2.451 1.00 32.17 O ANISOU 5079 O PRO E 469 3111 4488 4626 -230 -38 -1031 O ATOM 5080 N SER E 470 48.312 -19.099 -2.559 1.00 28.84 N ANISOU 5080 N SER E 470 3014 3820 4123 -340 103 -932 N ATOM 5081 CA SER E 470 48.702 -17.729 -2.427 1.00 29.49 C ANISOU 5081 CA SER E 470 3037 3929 4238 -515 142 -1067 C ATOM 5082 CB SER E 470 48.867 -17.093 -3.809 1.00 28.97 C ANISOU 5082 CB SER E 470 2956 3760 4289 -635 295 -1082 C ATOM 5083 OG SER E 470 49.175 -15.713 -3.679 1.00 29.55 O ANISOU 5083 OG SER E 470 3000 3813 4414 -824 336 -1197 O ATOM 5084 C SER E 470 47.631 -16.997 -1.653 1.00 28.74 C ANISOU 5084 C SER E 470 3092 3763 4065 -573 150 -1083 C ATOM 5085 O SER E 470 46.443 -17.255 -1.843 1.00 26.47 O ANISOU 5085 O SER E 470 2958 3353 3748 -526 203 -985 O ATOM 5086 N THR E 471 48.069 -16.067 -0.807 1.00 30.16 N ANISOU 5086 N THR E 471 3210 4030 4222 -681 102 -1231 N ATOM 5087 CA THR E 471 47.155 -15.195 -0.063 1.00 30.86 C ANISOU 5087 CA THR E 471 3415 4056 4254 -749 123 -1307 C ATOM 5088 CB THR E 471 47.566 -15.088 1.420 1.00 32.72 C ANISOU 5088 CB THR E 471 3592 4500 4342 -760 -10 -1427 C ATOM 5089 OG1 THR E 471 48.951 -14.718 1.504 1.00 37.22 O ANISOU 5089 OG1 THR E 471 3970 5205 4968 -843 -80 -1556 O ATOM 5090 CG2 THR E 471 47.380 -16.453 2.138 1.00 32.82 C ANISOU 5090 CG2 THR E 471 3640 4649 4181 -599 -122 -1281 C ATOM 5091 C THR E 471 47.026 -13.797 -0.691 1.00 30.99 C ANISOU 5091 C THR E 471 3462 3895 4418 -908 233 -1402 C ATOM 5092 O THR E 471 46.403 -12.895 -0.095 1.00 32.41 O ANISOU 5092 O THR E 471 3716 4003 4595 -969 251 -1512 O ATOM 5093 N GLU E 472 47.585 -13.628 -1.893 1.00 30.24 N ANISOU 5093 N GLU E 472 3317 3723 4448 -974 310 -1358 N ATOM 5094 CA GLU E 472 47.662 -12.324 -2.573 1.00 30.68 C ANISOU 5094 CA GLU E 472 3405 3604 4648 -1148 408 -1413 C ATOM 5095 CB GLU E 472 49.108 -11.861 -2.654 1.00 32.44 C ANISOU 5095 CB GLU E 472 3444 3937 4945 -1303 403 -1532 C ATOM 5096 CG GLU E 472 49.779 -11.668 -1.290 1.00 37.76 C ANISOU 5096 CG GLU E 472 3990 4801 5555 -1337 276 -1720 C ATOM 5097 CD GLU E 472 51.175 -12.305 -1.215 1.00 43.37 C ANISOU 5097 CD GLU E 472 4460 5762 6256 -1331 199 -1771 C ATOM 5098 OE1 GLU E 472 52.173 -11.548 -1.139 1.00 44.91 O ANISOU 5098 OE1 GLU E 472 4502 6025 6538 -1509 199 -1925 O ATOM 5099 OE2 GLU E 472 51.270 -13.569 -1.236 1.00 42.62 O ANISOU 5099 OE2 GLU E 472 4322 5787 6083 -1147 136 -1663 O ATOM 5100 C GLU E 472 47.062 -12.382 -3.974 1.00 28.59 C ANISOU 5100 C GLU E 472 3251 3164 4447 -1137 517 -1248 C ATOM 5101 O GLU E 472 46.385 -11.449 -4.397 1.00 28.12 O ANISOU 5101 O GLU E 472 3316 2897 4471 -1205 576 -1225 O ATOM 5102 N MSE E 473 47.284 -13.494 -4.682 1.00 27.02 N ANISOU 5102 N MSE E 473 3012 3048 4206 -1042 532 -1137 N ATOM 5103 CA MSE E 473 46.791 -13.651 -6.073 1.00 25.54 C ANISOU 5103 CA MSE E 473 2919 2739 4045 -1038 629 -993 C ATOM 5104 CB MSE E 473 47.927 -13.574 -7.115 1.00 25.96 C ANISOU 5104 CB MSE E 473 2858 2862 4144 -1159 717 -991 C ATOM 5105 CG MSE E 473 48.808 -12.339 -7.049 1.00 27.29 C ANISOU 5105 CG MSE E 473 2952 3011 4406 -1379 758 -1091 C ATOM 5106 SE MSE E 473 47.910 -10.662 -7.515 0.90 31.81 SE ANISOU 5106 SE MSE E 473 3749 3250 5087 -1541 823 -1021 SE ATOM 5107 CE MSE E 473 47.552 -10.998 -9.390 1.00 22.17 C ANISOU 5107 CE MSE E 473 2643 1969 3812 -1555 942 -793 C ATOM 5108 C MSE E 473 46.107 -14.980 -6.236 1.00 23.39 C ANISOU 5108 C MSE E 473 2695 2501 3691 -856 603 -890 C ATOM 5109 O MSE E 473 46.393 -15.922 -5.503 1.00 22.98 O ANISOU 5109 O MSE E 473 2572 2580 3579 -744 522 -910 O ATOM 5110 N SER E 474 45.225 -15.055 -7.218 1.00 21.86 N ANISOU 5110 N SER E 474 2624 2183 3498 -833 662 -776 N ATOM 5111 CA SER E 474 44.566 -16.309 -7.532 1.00 21.14 C ANISOU 5111 CA SER E 474 2578 2108 3346 -687 648 -690 C ATOM 5112 CB SER E 474 43.337 -16.499 -6.641 1.00 19.96 C ANISOU 5112 CB SER E 474 2523 1903 3156 -597 594 -671 C ATOM 5113 OG SER E 474 42.904 -17.839 -6.691 1.00 17.66 O ANISOU 5113 OG SER E 474 2253 1645 2812 -475 569 -603 O ATOM 5114 C SER E 474 44.153 -16.398 -9.009 1.00 21.27 C ANISOU 5114 C SER E 474 2672 2053 3359 -708 727 -592 C ATOM 5115 O SER E 474 43.946 -15.384 -9.652 1.00 20.89 O ANISOU 5115 O SER E 474 2694 1900 3342 -814 775 -549 O ATOM 5116 N MSE E 475 44.041 -17.620 -9.536 1.00 21.43 N ANISOU 5116 N MSE E 475 2683 2123 3336 -608 732 -558 N ATOM 5117 CA MSE E 475 43.337 -17.808 -10.790 1.00 22.35 C ANISOU 5117 CA MSE E 475 2894 2181 3417 -609 783 -475 C ATOM 5118 CB MSE E 475 43.262 -19.297 -11.154 1.00 21.85 C ANISOU 5118 CB MSE E 475 2809 2173 3321 -490 776 -482 C ATOM 5119 CG MSE E 475 44.593 -19.830 -11.643 1.00 24.48 C ANISOU 5119 CG MSE E 475 3003 2637 3663 -493 828 -563 C ATOM 5120 SE MSE E 475 44.487 -21.578 -12.470 0.90 25.13 SE ANISOU 5120 SE MSE E 475 3073 2746 3730 -353 842 -603 SE ATOM 5121 CE MSE E 475 44.118 -22.622 -10.880 1.00 14.68 C ANISOU 5121 CE MSE E 475 1759 1354 2463 -188 701 -580 C ATOM 5122 C MSE E 475 41.951 -17.191 -10.626 1.00 21.56 C ANISOU 5122 C MSE E 475 2925 1942 3326 -596 747 -409 C ATOM 5123 O MSE E 475 41.300 -17.398 -9.596 1.00 20.22 O ANISOU 5123 O MSE E 475 2769 1750 3164 -523 691 -430 O ATOM 5124 N ARG E 476 41.543 -16.382 -11.605 1.00 22.84 N ANISOU 5124 N ARG E 476 3174 2018 3486 -669 779 -331 N ATOM 5125 CA ARG E 476 40.252 -15.645 -11.593 1.00 23.43 C ANISOU 5125 CA ARG E 476 3359 1948 3596 -642 734 -269 C ATOM 5126 CB ARG E 476 40.013 -14.999 -12.975 1.00 24.07 C ANISOU 5126 CB ARG E 476 3538 1961 3647 -714 755 -147 C ATOM 5127 CG ARG E 476 38.593 -14.426 -13.168 1.00 27.79 C ANISOU 5127 CG ARG E 476 4110 2292 4159 -646 680 -70 C ATOM 5128 CD ARG E 476 38.209 -14.075 -14.619 1.00 28.50 C ANISOU 5128 CD ARG E 476 4305 2345 4177 -684 665 79 C ATOM 5129 NE ARG E 476 38.636 -14.995 -15.699 1.00 32.45 N ANISOU 5129 NE ARG E 476 4797 3003 4528 -722 716 104 N ATOM 5130 CZ ARG E 476 37.899 -15.993 -16.202 1.00 31.12 C ANISOU 5130 CZ ARG E 476 4629 2913 4282 -642 682 96 C ATOM 5131 NH1 ARG E 476 36.693 -16.294 -15.685 1.00 30.33 N ANISOU 5131 NH1 ARG E 476 4521 2762 4240 -526 601 71 N ATOM 5132 NH2 ARG E 476 38.385 -16.718 -17.191 1.00 25.61 N ANISOU 5132 NH2 ARG E 476 3925 2354 3452 -687 739 89 N ATOM 5133 C ARG E 476 39.015 -16.489 -11.142 1.00 21.83 C ANISOU 5133 C ARG E 476 3173 1741 3380 -513 681 -273 C ATOM 5134 O ARG E 476 38.679 -17.503 -11.745 1.00 21.04 O ANISOU 5134 O ARG E 476 3079 1693 3224 -465 681 -247 O ATOM 5135 N GLY E 477 38.372 -16.052 -10.058 1.00 21.70 N ANISOU 5135 N GLY E 477 3157 1672 3416 -473 646 -324 N ATOM 5136 CA GLY E 477 37.207 -16.716 -9.484 1.00 20.09 C ANISOU 5136 CA GLY E 477 2953 1479 3200 -382 617 -338 C ATOM 5137 C GLY E 477 37.443 -18.027 -8.755 1.00 19.41 C ANISOU 5137 C GLY E 477 2821 1499 3053 -341 617 -363 C ATOM 5138 O GLY E 477 36.471 -18.609 -8.296 1.00 19.64 O ANISOU 5138 O GLY E 477 2856 1537 3067 -294 607 -361 O ATOM 5139 N ILE E 478 38.696 -18.502 -8.647 1.00 18.91 N ANISOU 5139 N ILE E 478 2708 1514 2965 -357 623 -381 N ATOM 5140 CA ILE E 478 39.017 -19.810 -8.023 1.00 17.77 C ANISOU 5140 CA ILE E 478 2530 1443 2777 -297 599 -380 C ATOM 5141 CB ILE E 478 40.039 -20.648 -8.855 1.00 18.55 C ANISOU 5141 CB ILE E 478 2584 1586 2878 -277 612 -379 C ATOM 5142 CG1 ILE E 478 39.751 -20.616 -10.374 1.00 17.27 C ANISOU 5142 CG1 ILE E 478 2459 1391 2711 -306 659 -354 C ATOM 5143 CD1 ILE E 478 38.418 -21.271 -10.824 1.00 13.13 C ANISOU 5143 CD1 ILE E 478 2003 811 2174 -270 646 -315 C ATOM 5144 CG2 ILE E 478 40.182 -22.098 -8.267 1.00 18.35 C ANISOU 5144 CG2 ILE E 478 2547 1581 2843 -186 567 -361 C ATOM 5145 C ILE E 478 39.616 -19.651 -6.599 1.00 18.69 C ANISOU 5145 C ILE E 478 2602 1637 2863 -298 561 -430 C ATOM 5146 O ILE E 478 40.569 -18.901 -6.395 1.00 18.45 O ANISOU 5146 O ILE E 478 2515 1647 2850 -348 556 -490 O ATOM 5147 N ARG E 479 39.035 -20.351 -5.617 1.00 18.39 N ANISOU 5147 N ARG E 479 2589 1632 2767 -257 533 -405 N ATOM 5148 CA ARG E 479 39.554 -20.346 -4.253 1.00 19.06 C ANISOU 5148 CA ARG E 479 2644 1820 2777 -256 483 -435 C ATOM 5149 CB ARG E 479 38.638 -19.533 -3.312 1.00 19.09 C ANISOU 5149 CB ARG E 479 2674 1845 2733 -297 507 -498 C ATOM 5150 CG ARG E 479 38.471 -18.073 -3.712 1.00 20.34 C ANISOU 5150 CG ARG E 479 2824 1925 2979 -348 545 -592 C ATOM 5151 CD ARG E 479 39.752 -17.232 -3.507 1.00 22.85 C ANISOU 5151 CD ARG E 479 3081 2279 3322 -408 517 -680 C ATOM 5152 NE ARG E 479 39.500 -15.800 -3.765 1.00 25.19 N ANISOU 5152 NE ARG E 479 3393 2459 3718 -468 552 -765 N ATOM 5153 CZ ARG E 479 39.487 -15.222 -4.979 1.00 27.21 C ANISOU 5153 CZ ARG E 479 3679 2582 4078 -498 582 -718 C ATOM 5154 NH1 ARG E 479 39.709 -15.928 -6.090 1.00 26.37 N ANISOU 5154 NH1 ARG E 479 3581 2470 3970 -482 595 -610 N ATOM 5155 NH2 ARG E 479 39.248 -13.924 -5.085 1.00 26.41 N ANISOU 5155 NH2 ARG E 479 3609 2347 4078 -547 597 -780 N ATOM 5156 C ARG E 479 39.697 -21.757 -3.727 1.00 19.49 C ANISOU 5156 C ARG E 479 2720 1912 2775 -189 429 -345 C ATOM 5157 O ARG E 479 38.976 -22.661 -4.158 1.00 18.74 O ANISOU 5157 O ARG E 479 2681 1743 2697 -162 449 -271 O ATOM 5158 N VAL E 480 40.609 -21.940 -2.772 1.00 20.82 N ANISOU 5158 N VAL E 480 2847 2187 2876 -166 349 -348 N ATOM 5159 CA VAL E 480 40.767 -23.248 -2.116 1.00 21.96 C ANISOU 5159 CA VAL E 480 3031 2353 2960 -92 271 -232 C ATOM 5160 CB VAL E 480 42.207 -23.838 -2.322 1.00 22.03 C ANISOU 5160 CB VAL E 480 2948 2393 3028 3 178 -229 C ATOM 5161 CG1 VAL E 480 42.429 -25.077 -1.472 1.00 22.81 C ANISOU 5161 CG1 VAL E 480 3098 2500 3069 9.

63. 94 C ATOM 5162 CG2 VAL E 480 42.460 -24.160 -3.772 1.00 20.19 C ANISOU 5162 CG2 VAL E 480 2677 2061 2932 38 234 -261 C ATOM 5163 C VAL E 480 40.412 -23.122 -0.620 1.00 23.54 C ANISOU 5163 C VAL E 480 3277 2674 2994 -131 235 -206 C ATOM 5164 O VAL E 480 40.953 -22.280 0.097 1.00 24.05 O ANISOU 5164 O VAL E 480 3287 2864 2988 -167 198 -300 O ATOM 5165 N SER E 481 39.492 -23.966 -0.161 1.00 24.81 N ANISOU 5165 N SER E 481 3538 2808 3083 -141 253 -88 N ATOM 5166 CA SER E 481 39.093 -24.015 1.249 1.00 26.08 C ANISOU 5166 CA SER E 481 3757 3104 3048 -193 236 -40 C ATOM 5167 CB SER E 481 37.836 -24.872 1.399 1.00 25.78 C ANISOU 5167 CB SER E 481 3824 3003 2969 -243 310 83 C ATOM 5168 OG SER E 481 37.426 -24.964 2.750 1.00 25.77 O ANISOU 5168 OG SER E 481 3886 3155 2752 -316 315 141 O ATOM 5169 C SER E 481 40.194 -24.566 2.157 1.00 28.89 C ANISOU 5169 C SER E 481 4114 3570 3294 -131 82 47 C ATOM 5170 O SER E 481 40.829 -25.579 1.858 1.00 29.34 O ANISOU 5170 O SER E 481 4181 3543 3423 -9 161 O ATOM 5171 N LYS E 482 40.406 -23.902 3.280 1.00 31.33 N ANISOU 5171 N LYS E 482 4407 4070 3426 -183.

44. 16 N ATOM 5172 CA LYS E 482 41.264 -24.437 4.320 1.00 35.34 C ANISOU 5172 CA LYS E 482 4931 4720 3776 -135 -119 86 C ATOM 5173 CB LYS E 482 42.004 -23.295 5.021 1.00 36.93 C ANISOU 5173 CB LYS E 482 5031 5127 3875 -177 -179 -95 C ATOM 5174 CG LYS E 482 43.111 -22.672 4.207 1.00 38.22 C ANISOU 5174 CG LYS E 482 5038 5259 4224 -134 -219 -240 C ATOM 5175 CD LYS E 482 43.698 -21.521 4.982 1.00 44.98 C ANISOU 5175 CD LYS E 482 5803 6309 4977 -211 -267 -433 C ATOM 5176 CE LYS E 482 45.223 -21.561 4.968 1.00 47.96 C ANISOU 5176 CE LYS E 482 6028 6783 5410 -142 -430 -476 C ATOM 5177 NZ LYS E 482 45.777 -20.298 5.551 1.00 50.79 N ANISOU 5177 NZ LYS E 482 6280 7307 5710 -250 -458 -708 N ATOM 5178 C LYS E 482 40.480 -25.277 5.345 1.00 37.85 C ANISOU 5178 C LYS E 482 5402 5097 3882 -186 -120 278 C ATOM 5179 O LYS E 482 41.059 -25.722 6.324 1.00 40.42 O ANISOU 5179 O LYS E 482 5770 5557 4030 -157 -263 396 O ATOM 5180 N MSE E 483 39.178 -25.477 5.113 1.00 38.08 N ANISOU 5180 N MSE E 483 5507 5039 3923 -271 35 313 N ATOM 5181 CA MSE E 483 38.319 -26.309 5.975 1.00 41.13 C ANISOU 5181 CA MSE E 483 6038 5469 4121 -357 73 501 C ATOM 5182 CB MSE E 483 36.882 -25.754 6.064 1.00 40.37 C ANISOU 5182 CB MSE E 483 5941 5421 3976 -498 279 393 C ATOM 5183 CG MSE E 483 36.761 -24.265 6.345 1.00 40.01 C ANISOU 5183 CG MSE E 483 5787 5531 3882 -542 350 123 C ATOM 5184 SE MSE E 483 37.684 -23.720 7.991 0.90 48.53 SE ANISOU 5184 SE MSE E 483 6871 6944 4625 -576 224 65 SE ATOM 5185 CE MSE E 483 36.796 -24.873 9.310 1.00 39.30 C ANISOU 5185 CE MSE E 483 5885 5939 3108 -711 273 332 C ATOM 5186 C MSE E 483 38.246 -27.706 5.373 1.00 42.30 C ANISOU 5186 C MSE E 483 6281 5381 4412 -297 34 716 C ATOM 5187 O MSE E 483 37.810 -27.893 4.207 1.00 41.41 O ANISOU 5187 O MSE E 483 6140 5074 4520 -280 115 669 O ATOM 5188 OXT MSE E 483 38.610 -28.668 6.048 1.00 45.09 O ANISOU 5188 OXT MSE E 483 6745 5727 4660 -266 -87 937 O ATOM 5189 N SER F 322 34.011 6.452 -60.832 1.00 64.98 N ANISOU 5189 N SER F 322 10039 10556 4093 -1803 691 1251 N ATOM 5190 CA SER F 322 32.816 6.735 -59.979 1.00 62.59 C ANISOU 5190 CA SER F 322 9734 10002 4046 -1536 361 1309 C ATOM 5191 CB SER F 322 32.604 8.243 -59.821 1.00 64.65 C ANISOU 5191 CB SER F 322 10337 9931 4296 -1631 298 1564 C ATOM 5192 OG SER F 322 33.389 8.747 -58.754 1.00 65.13 O ANISOU 5192 OG SER F 322 10229 9915 4604 -1806 456 1515 O ATOM 5193 C SER F 322 31.562 6.093 -60.548 1.00 61.62 C ANISOU 5193 C SER F 322 9683 9900 3831 -1253 68 1295 C ATOM 5194 O SER F 322 31.304 6.186 -61.745 1.00 64.33 O ANISOU 5194 O SER F 322 10330 10282 3832 -1271 13 1407 O ATOM 5195 N PHE F 323 30.793 5.447 -59.672 1.00 57.78 N ANISOU 5195 N PHE F 323 8921 9391 3643 -1013 -115 1152 N ATOM 5196 CA PHE F 323 29.540 4.774 -60.034 1.00 56.60 C ANISOU 5196 CA PHE F 323 8754 9271 3481 -759 -400 1094 C ATOM 5197 CB PHE F 323 29.803 3.472 -60.817 1.00 56.49 C ANISOU 5197 CB PHE F 323 8646 9535 3285 -767 -321 906 C ATOM 5198 CG PHE F 323 30.640 2.458 -60.073 1.00 53.82 C ANISOU 5198 CG PHE F 323 7956 9345 3148 -799 -105 669 C ATOM 5199 CD1 PHE F 323 30.039 1.474 -59.298 1.00 49.66 C ANISOU 5199 CD1 PHE F 323 7167 8820 2880 -621 -219 487 C ATOM 5200 CE1 PHE F 323 30.800 0.533 -58.628 1.00 48.33 C ANISOU 5200 CE1 PHE F 323 6732 8755 2877 -621 -52 290 C ATOM 5201 CZ PHE F 323 32.182 0.565 -58.719 1.00 49.24 C ANISOU 5201 CZ PHE F 323 6772 9006 2930 -778 220 248 C ATOM 5202 CE2 PHE F 323 32.796 1.537 -59.491 1.00 52.46 C ANISOU 5202 CE2 PHE F 323 7386 9446 3100 -985 365 404 C ATOM 5203 CD2 PHE F 323 32.028 2.476 -60.167 1.00 54.43 C ANISOU 5203 CD2 PHE F 323 7968 9559 3154 -1005 210 625 C ATOM 5204 C PHE F 323 28.693 4.508 -58.789 1.00 53.34 C ANISOU 5204 C PHE F 323 8069 8746 3453 -555 -559 984 C ATOM 5205 O PHE F 323 28.952 5.075 -57.735 1.00 52.04 O ANISOU 5205 O PHE F 323 7823 8434 3515 -588 -490 1003 O ATOM 5206 N SER F 324 27.717 3.610 -58.913 1.00 52.31 N ANISOU 5206 N SER F 324 7801 8693 3380 -371 -751 850 N ATOM 5207 CA SER F 324 26.659 3.430 -57.923 1.00 50.15 C ANISOU 5207 CA SER F 324 7311 8311 3432 -183 -917 760 C ATOM 5208 CB SER F 324 25.461 4.292 -58.342 1.00 52.27 C ANISOU 5208 CB SER F 324 7742 8435 3685 -5 -1217 905 C ATOM 5209 OG SER F 324 24.546 4.524 -57.289 1.00 51.91 O ANISOU 5209 OG SER F 324 7504 8244 3975 161 -1325 848 O ATOM 5210 C SER F 324 26.254 1.948 -57.864 1.00 48.44 C ANISOU 5210 C SER F 324 6852 8258 3293 -116 -945 520 C ATOM 5211 O SER F 324 26.075 1.322 -58.895 1.00 50.04 O ANISOU 5211 O SER F 324 7125 8610 3280 -114 -1019 464 O ATOM 5212 N PHE F 325 26.129 1.389 -56.660 1.00 45.78 N ANISOU 5212 N PHE F 325 6271 7878 3245 -79 -878 379 N ATOM 5213 CA PHE F 325 25.670 -0.004 -56.478 1.00 43.79 C ANISOU 5213 CA PHE F 325 5824 7722 3091 -32 -896 158 C ATOM 5214 CB PHE F 325 26.785 -1.009 -56.819 1.00 43.32 C ANISOU 5214 CB PHE F 325 5751 7815 2894 -128 -702 38 C ATOM 5215 CG PHE F 325 26.407 -2.453 -56.596 1.00 42.81 C ANISOU 5215 CG PHE F 325 5543 7795 2927 -86 -705 -186 C ATOM 5216 CD1 PHE F 325 25.471 -3.087 -57.424 1.00 45.16 C ANISOU 5216 CD1 PHE F 325 5857 8167 3136 -52 -875 -288 C ATOM 5217 CE1 PHE F 325 25.112 -4.424 -57.209 1.00 44.54 C ANISOU 5217 CE1 PHE F 325 5674 8097 3153 -49 -865 -503 C ATOM 5218 CZ PHE F 325 25.706 -5.150 -56.167 1.00 42.37 C ANISOU 5218 CZ PHE F 325 5311 7741 3047 -53 -689 -594 C ATOM 5219 CE2 PHE F 325 26.651 -4.536 -55.348 1.00 40.54 C ANISOU 5219 CE2 PHE F 325 5059 7456 2890 -58 -547 -487 C ATOM 5220 CD2 PHE F 325 26.989 -3.188 -55.561 1.00 41.44 C ANISOU 5220 CD2 PHE F 325 5244 7577 2924 -88 -552 -295 C ATOM 5221 C PHE F 325 25.132 -0.224 -55.053 1.00 41.64 C ANISOU 5221 C PHE F 325 5353 7325 314.

26. 873 66 C ATOM 5222 O PHE F 325 25.807 0.091 -54.067 1.00 39.51 O ANISOU 5222 O PHE F 325 5054 6968 2990 -727 92 O ATOM 5223 N GLY F 326 23.906 -0.747 -54.969 1.00 41.53 N ANISOU 5223 N GLY F 326 5205 7311 3264 109 -1015 -51 N ATOM 5224 CA GLY F 326 23.229 -1.041 -53.700 1.00 39.72 C ANISOU 5224 CA GLY F 326 4794 6976 3322 140 -970 -158 C ATOM 5225 C GLY F 326 23.119 0.104 -52.706 1.00 39.23 C ANISOU 5225 C GLY F 326 4733 6746 3427 187 -931 -57 C ATOM 5226 O GLY F 326 23.248 -0.105 -51.503 1.00 37.01 O ANISOU 5226 O GLY F 326 4384 6376 3302 155 -790 -119 O ATOM 5227 N GLY F 327 22.887 1.309 -53.220 1.00 40.74 N ANISOU 5227 N GLY F 327 5040 6875 3563 264 -1061 99 N ATOM 5228 CA GLY F 327 22.741 2.501 -52.404 1.00 41.28 C ANISOU 5228 CA GLY F 327 5152 6754 3780 325 -1040 192 C ATOM 5229 C GLY F 327 24.066 3.126 -51.996 1.00 40.95 C ANISOU 5229 C GLY F 327 5272 6631 3655 195 -873 305 C ATOM 5230 O GLY F 327 24.101 4.024 -51.162 1.00 40.80 O ANISOU 5230 O GLY F 327 5305 6440 3756 207 -821 353 O ATOM 5231 N PHE F 328 25.160 2.646 -52.578 1.00 40.57 N ANISOU 5231 N PHE F 328 5289 6716 341.

64. 781 323 N ATOM 5232 CA PHE F 328 26.480 3.152 -52.254 1.00 40.14 C ANISOU 5232 CA PHE F 328 5327 6634 3289 -87 -619 398 C ATOM 5233 CB PHE F 328 27.337 2.054 -51.593 1.00 38.59 C ANISOU 5233 CB PHE F 328 4985 6548 3129 -161 -471 255 C ATOM 5234 CG PHE F 328 26.937 1.747 -50.172 1.00 36.26 C ANISOU 5234 CG PHE F 328 4584 6146 3047 -114 -436 152 C ATOM 5235 CD1 PHE F 328 27.509 2.439 -49.118 1.00 35.56 C ANISOU 5235 CD1 PHE F 328 4532 5943 3037 -180 -359 178 C ATOM 5236 CE1 PHE F 328 27.135 2.179 -47.794 1.00 35.95 C ANISOU 5236 CE1 PHE F 328 4532 5891 3238 -147 -318 85 C ATOM 5237 CZ PHE F 328 26.175 1.205 -47.525 1.00 35.59 C ANISOU 5237 CZ PHE F 328 4392 5853 3279 -67 -328 -30 C ATOM 5238 CE2 PHE F 328 25.579 0.501 -48.591 1.00 35.31 C ANISOU 5238 CE2 PHE F 328 4292 5930 3195 -16 -406 -67 C ATOM 5239 CD2 PHE F 328 25.972 0.772 -49.896 1.00 36.57 C ANISOU 5239 CD2 PHE F 328 4509 6196 3191 -31 -472 21 C ATOM 5240 C PHE F 328 27.164 3.747 -53.487 1.00 42.14 C ANISOU 5240 C PHE F 328 5784 6945 3284 -188 -612 551 C ATOM 5241 O PHE F 328 27.123 3.162 -54.574 1.00 43.04 O ANISOU 5241 O PHE F 328 5930 7212 3211 -186 -657 538 O ATOM 5242 N THR F 329 27.753 4.931 -53.308 1.00 43.06 N ANISOU 5242 N THR F 329 6063 6922 3376 -296 -547 691 N ATOM 5243 CA THR F 329 28.590 5.562 -54.324 1.00 44.99 C ANISOU 5243 CA THR F 329 6526 7199 3369 -463 -471 842 C ATOM 5244 CB THR F 329 28.582 7.124 -54.212 1.00 47.13 C ANISOU 5244 CB THR F 329 7067 7201 3639 -520 -492 1036 C ATOM 5245 OG1 THR F 329 27.239 7.622 -54.309 1.00 47.99 O ANISOU 5245 OG1 THR F 329 7274 7135 3825 -281 -725 1105 O ATOM 5246 CG2 THR F 329 29.435 7.782 -55.313 1.00 49.33 C ANISOU 5246 CG2 THR F 329 7622 7494 3626 -739 -385 1209 C ATOM 5247 C THR F 329 30.011 5.037 -54.169 1.00 44.33 C ANISOU 5247 C THR F 329 6307 7296 3238 -659 -242 750 C ATOM 5248 O THR F 329 30.661 5.270 -53.164 1.00 43.50 O ANISOU 5248 O THR F 329 6103 7145 3278 -750 -146 702 O ATOM 5249 N PHE F 330 30.485 4.299 -55.160 1.00 45.43 N ANISOU 5249 N PHE F 330 6430 7653 3179 -712 -166 704 N ATOM 5250 CA PHE F 330 31.856 3.815 -55.144 1.00 45.51 C ANISOU 5250 CA PHE F 330 6284 7859 3150 -873 57 599 C ATOM 5251 CB PHE F 330 31.974 2.448 -55.811 1.00 44.24 C ANISOU 5251 CB PHE F 330 5998 7924 2886 -793 95 438 C ATOM 5252 CG PHE F 330 31.265 1.341 -55.083 1.00 41.56 C ANISOU 5252 CG PHE F 330 5484 7570 2737 -593 -24 281 C ATOM 5253 CD1 PHE F 330 31.970 0.227 -54.643 1.00 39.01 C ANISOU 5253 CD1 PHE F 330 4950 7373 2501 -551 72 97 C ATOM 5254 CE1 PHE F 330 31.319 -0.811 -53.999 1.00 36.87 C ANISOU 5254 CE1 PHE F 330 4580 7051 2379 -392 -23 -32 C ATOM 5255 CZ PHE F 330 29.941 -0.742 -53.767 1.00 36.29 C ANISOU 5255 CZ PHE F 330 4566 6835 2390 -298 -191 0 C ATOM 5256 CE2 PHE F 330 29.229 0.364 -54.190 1.00 37.65 C ANISOU 5256 CE2 PHE F 330 4887 6913 2505 -313 -297 159 C ATOM 5257 CD2 PHE F 330 29.886 1.396 -54.852 1.00 39.87 C ANISOU 5257 CD2 PHE F 330 5319 7211 2619 -446 -227 310 C ATOM 5258 C PHE F 330 32.713 4.818 -55.875 1.00 48.65 C ANISOU 5258 C PHE F 330 6873 8264 3348 -1124 219 745 C ATOM 5259 O PHE F 330 32.259 5.448 -56.807 1.00 50.59 O ANISOU 5259 O PHE F 330 7408 8428 3384 -1150 160 912 O ATOM 5260 N LYS F 331 33.946 4.979 -55.416 1.00 50.04 N ANISOU 5260 N LYS F 331 6892 8531 3590 -1318 414 680 N ATOM 5261 CA LYS F 331 34.964 5.753 -56.116 1.00 53.68 C ANISOU 5261 CA LYS F 331 7471 9055 3869 -1620 639 769 C ATOM 5262 CB LYS F 331 35.231 7.083 -55.410 1.00 55.11 C ANISOU 5262 CB LYS F 331 7777 9006 4157 -1811 660 889 C ATOM 5263 CG LYS F 331 34.021 7.996 -55.305 1.00 58.38 C ANISOU 5263 CG LYS F 331 8516 9084 4581 -1684 447 1080 C ATOM 5264 CD LYS F 331 34.421 9.467 -55.258 1.00 65.79 C ANISOU 5264 CD LYS F 331 9739 9778 5479 -1948 534 1252 C ATOM 5265 CE LYS F 331 33.390 10.311 -56.018 1.00 69.37 C ANISOU 5265 CE LYS F 331 10638 9954 5763 -1842 370 1498 C ATOM 5266 NZ LYS F 331 33.674 11.800 -55.808 1.00 74.95 N ANISOU 5266 NZ LYS F 331 11678 10334 6466 -2070 432 1671 N ATOM 5267 C LYS F 331 36.204 4.910 -56.034 1.00 53.61 C ANISOU 5267 C LYS F 331 7117 9344 3907 -1704 845 557 C ATOM 5268 O LYS F 331 36.661 4.624 -54.932 1.00 51.96 O ANISOU 5268 O LYS F 331 6638 9168 3938 -1666 824 424 O ATOM 5269 N ARG F 332 36.740 4.480 -57.175 1.00 55.82 N ANISOU 5269 N ARG F 332 7406 9846 3958 -1795 1035 512 N ATOM 5270 CA ARG F 332 37.975 3.711 -57.141 1.00 56.45 C ANISOU 5270 CA ARG F 332 7126 10222 4102 -1854 1251 286 C ATOM 5271 CB ARG F 332 38.200 2.902 -58.417 1.00 58.54 C ANISOU 5271 CB ARG F 332 7413 10718 4111 -1836 1419 191 C ATOM 5272 CG ARG F 332 39.426 1.993 -58.330 1.00 58.83 C ANISOU 5272 CG ARG F 332 7035 11059 4257 -1823 1632 -82 C ATOM 5273 CD ARG F 332 39.626 1.183 -59.593 1.00 60.93 C ANISOU 5273 CD ARG F 332 7343 11542 4265 -1793 1821 -205 C ATOM 5274 NE ARG F 332 40.094 1.998 -60.711 1.00 63.73 N ANISOU 5274 NE ARG F 332 7925 11986 4305 -2121 2102 -93 N ATOM 5275 CZ ARG F 332 39.945 1.662 -61.989 1.00 67.27 C ANISOU 5275 CZ ARG F 332 8607 12545 4407 -2151 2238 -103 C ATOM 5276 NH1 ARG F 332 39.334 0.528 -62.321 1.00 65.85 N ANISOU 5276 NH1 ARG F 332 8448 12400 4171 -1873 2106 -235 N ATOM 5277 NH2 ARG F 332 40.400 2.464 -62.946 1.00 71.36 N ANISOU 5277 NH2 ARG F 332 9373 13127 4613 -2480 2512 18 N ATOM 5278 C ARG F 332 39.138 4.648 -56.879 1.00 58.97 C ANISOU 5278 C ARG F 332 7335 10596 4475 -2189 1464 297 C ATOM 5279 O ARG F 332 39.386 5.586 -57.629 1.00 61.80 O ANISOU 5279 O ARG F 332 7943 10911 4627 -2474 1635 449 O ATOM 5280 N THR F 333 39.841 4.386 -55.789 1.00 58.21 N ANISOU 5280 N THR F 333 6878 10586 4652 -2165 1442 134 N ATOM 5281 CA THR F 333 40.945 5.229 -55.366 1.00 60.07 C ANISOU 5281 CA THR F 333 6945 10888 4991 -2487 1602 103 C ATOM 5282 CB THR F 333 40.955 5.395 -53.809 1.00 57.87 C ANISOU 5282 CB THR F 333 6499 10485 5005 -2405 1378 45 C ATOM 5283 OG1 THR F 333 40.820 4.116 -53.173 1.00 53.94 O ANISOU 5283 OG1 THR F 333 5755 10082 4659 -2055 1210 -124 O ATOM 5284 CG2 THR F 333 39.781 6.265 -53.360 1.00 55.42 C ANISOU 5284 CG2 THR F 333 6572 9793 4692 -2367 1177 257 C ATOM 5285 C THR F 333 42.260 4.664 -55.913 1.00 63.49 C ANISOU 5285 C THR F 333 7009 11703 5413 -2612 1892 -115 C ATOM 5286 O THR F 333 43.229 5.410 -56.156 1.00 66.66 O ANISOU 5286 O THR F 333 7310 12223 5793 -2977 2143 -133 O ATOM 5287 N SER F 334 42.274 3.351 -56.144 1.00 62.58 N ANISOU 5287 N SER F 334 6695 11769 5312 -2317 1875 -291 N ATOM 5288 CA SER F 334 43.502 2.644 -56.507 1.00 65.70 C ANISOU 5288 CA SER F 334 6674 12530 5758 -2338 2121 -550 C ATOM 5289 CB SER F 334 44.291 2.301 -55.244 1.00 65.54 C ANISOU 5289 CB SER F 334 6199 12626 6076 -2225 1985 -745 C ATOM 5290 OG SER F 334 44.801 3.472 -54.626 1.00 68.04 O ANISOU 5290 OG SER F 334 6457 12896 6498 -2553 2002 -685 O ATOM 5291 C SER F 334 43.246 1.357 -57.283 1.00 65.13 C ANISOU 5291 C SER F 334 6595 12586 5565 -2050 2161 -684 C ATOM 5292 O SER F 334 42.223 0.701 -57.097 1.00 62.02 O ANISOU 5292 O SER F 334 6381 12018 5168 -1758 1918 -644 O ATOM 5293 N GLY F 335 44.195 0.999 -58.142 1.00 68.40 N ANISOU 5293 N GLY F 335 6793 13307 5888 -2150 2488 -866 N ATOM 5294 CA GLY F 335 44.157 -0.277 -58.850 1.00 68.50 C ANISOU 5294 CA GLY F 335 6754 13467 5808 -1876 2563 -1055 C ATOM 5295 C GLY F 335 43.389 -0.225 -60.154 1.00 68.74 C ANISOU 5295 C GLY F 335 7239 13435 5445 -1951 2668 -925 C ATOM 5296 O GLY F 335 43.026 0.858 -60.629 1.00 69.46 O ANISOU 5296 O GLY F 335 7680 13399 5314 -2236 2722 -681 O ATOM 5297 N SER F 336 43.149 -1.405 -60.731 1.00 68.37 N ANISOU 5297 N SER F 336 7212 13464 5303 -1688 2679 -1092 N ATOM 5298 CA SER F 336 42.397 -1.531 -61.986 1.00 69.05 C ANISOU 5298 CA SER F 336 7727 13513 4996 -1723 2739 -1010 C ATOM 5299 CB SER F 336 43.217 -1.023 -63.178 1.00 73.61 C ANISOU 5299 CB SER F 336 8375 14331 5263 -2063 3179 -1036 C ATOM 5300 OG SER F 336 44.204 -1.967 -63.529 1.00 76.75 O ANISOU 5300 OG SER F 336 8413 15033 5715 -1957 3464 -1374 O ATOM 5301 C SER F 336 41.939 -2.968 -62.240 1.00 67.73 C ANISOU 5301 C SER F 336 7568 13350 4817 -1369 2631 -1214 C ATOM 5302 O SER F 336 42.344 -3.898 -61.517 1.00 66.67 O ANISOU 5302 O SER F 336 7102 13257 4972 -1096 2562 -1428 O ATOM 5303 N SER F 337 41.095 -3.128 -63.279 1.00 68.08 N ANISOU 5303 N SER F 337 8018 13336 4512 -1379 2602 -1144 N ATOM 5304 CA SER F 337 40.508 -4.417 -63.644 1.00 67.00 C ANISOU 5304 CA SER F 337 7973 13170 4315 -1097 2486 -1327 C ATOM 5305 CB SER F 337 39.336 -4.739 -62.720 1.00 62.53 C ANISOU 5305 CB SER F 337 7481 12315 3961 -875 2064 -1229 C ATOM 5306 OG SER F 337 38.333 -3.755 -62.848 1.00 60.99 O ANISOU 5306 OG SER F 337 7612 11944 3619 -1016 1861 -934 O ATOM 5307 C SER F 337 40.018 -4.501 -65.096 1.00 69.66 C ANISOU 5307 C SER F 337 8719 13566 4183 -1202 2583 -1314 C ATOM 5308 O SER F 337 39.755 -3.477 -65.752 1.00 70.99 O ANISOU 5308 O SER F 337 9208 13715 4051 -1462 2625 -1078 O ATOM 5309 N ILE F 338 39.898 -5.738 -65.580 1.00 70.19 N ANISOU 5309 N ILE F 338 8806 13686 4178 -994 2605 -1570 N ATOM 5310 CA ILE F 338 39.155 -6.038 -66.796 1.00 71.90 C ANISOU 5310 CA ILE F 338 9439 13908 3972 -1029 2574 -1583 C ATOM 5311 CB ILE F 338 40.002 -6.853 -67.853 1.00 76.35 C ANISOU 5311 CB ILE F 338 9987 14730 4290 -1023 2965 -1906 C ATOM 5312 CG1 ILE F 338 40.263 -8.298 -67.393 1.00 75.23 C ANISOU 5312 CG1 ILE F 338 9575 14570 4439 -678 2951 -2246 C ATOM 5313 CD1 ILE F 338 40.863 -9.201 -68.486 1.00 80.18 C ANISOU 5313 CD1 ILE F 338 10254 15401 4810 -623 3291 -2589 C ATOM 5314 CG2 ILE F 338 41.320 -6.112 -68.205 1.00 78.90 C ANISOU 5314 CG2 ILE F 338 10131 15320 4527 -1288 3428 -1925 C ATOM 5315 C ILE F 338 37.828 -6.734 -66.425 1.00 68.91 C ANISOU 5315 C ILE F 338 9200 13287 3697 -806 2150 -1576 C ATOM 5316 O ILE F 338 37.757 -7.445 -65.419 1.00 66.10 O ANISOU 5316 O ILE F 338 8600 12808 3708 -581 2005 -1683 O ATOM 5317 N LYS F 339 36.784 -6.500 -67.226 1.00 69.74 N ANISOU 5317 N LYS F 339 9700 13325 3473 -882 1949 -1445 N ATOM 5318 CA LYS F 339 35.463 -7.116 -67.021 1.00 67.74 C ANISOU 5318 CA LYS F 339 9570 12878 3290 -720 1556 -1458 C ATOM 5319 CB LYS F 339 34.333 -6.139 -67.371 1.00 67.59 C ANISOU 5319 CB LYS F 339 9864 12753 3064 -831 1250 -1160 C ATOM 5320 CG LYS F 339 34.393 -4.798 -66.699 1.00 66.44 C ANISOU 5320 CG LYS F 339 9674 12510 3061 -940 1203 -852 C ATOM 5321 CD LYS F 339 33.675 -3.720 -67.540 1.00 68.91 C ANISOU 5321 CD LYS F 339 10398 12778 3007 -1082 1029 -569 C ATOM 5322 CE LYS F 339 34.362 -2.348 -67.345 1.00 70.79 C ANISOU 5322 CE LYS F 339 10682 12989 3227 -1292 1208 -308 C ATOM 5323 NZ LYS F 339 34.350 -1.864 -65.889 1.00 67.41 N ANISOU 5323 NZ LYS F 339 9955 12387 3271 -1227 1105 -208 N ATOM 5324 C LYS F 339 35.324 -8.349 -67.910 1.00 70.21 C ANISOU 5324 C LYS F 339 10033 13263 3382 -630 1607 -1759 C ATOM 5325 O LYS F 339 35.364 -8.238 -69.132 1.00 73.21 O ANISOU 5325 O LYS F 339 10707 13787 3321 -763 1726 -1788 O ATOM 5326 N ARG F 340 35.143 -9.514 -67.302 1.00 68.86 N ANISOU 5326 N ARG F 340 9700 12972 3492 -415 1515 -1980 N ATOM 5327 CA ARG F 340 35.046 -10.755 -68.056 1.00 71.85 C ANISOU 5327 CA ARG F 340 10224 13375 3699 -321 1570 -2296 C ATOM 5328 CB ARG F 340 36.226 -11.677 -67.715 1.00 72.59 C ANISOU 5328 CB ARG F 340 10046 13519 4016 -132 1871 -2586 C ATOM 5329 CG ARG F 340 36.403 -12.842 -68.679 1.00 76.97 C ANISOU 5329 CG ARG F 340 10775 14131 4338 -46 2034 -2942 C ATOM 5330 CD ARG F 340 37.468 -13.841 -68.233 1.00 78.54 C ANISOU 5330 CD ARG F 340 10696 14325 4818 215 2278 -3243 C ATOM 5331 NE ARG F 340 37.621 -14.943 -69.196 1.00 86.31 N ANISOU 5331 NE ARG F 340 11880 15342 5571 307 2449 -3605 N ATOM 5332 CZ ARG F 340 36.819 -16.011 -69.279 1.00 87.14 C ANISOU 5332 CZ ARG F 340 12201 15224 5684 409 2247 -3787 C ATOM 5333 NH1 ARG F 340 35.781 -16.154 -68.451 1.00 84.58 N ANISOU 5333 NH1 ARG F 340 11903 14639 5593 422 1877 -3641 N ATOM 5334 NH2 ARG F 340 37.058 -16.949 -70.188 1.00 89.57 N ANISOU 5334 NH2 ARG F 340 12702 15565 5765 482 2435 -4134 N ATOM 5335 C ARG F 340 33.708 -11.429 -67.754 1.00 70.08 C ANISOU 5335 C ARG F 340 10105 12931 3592 -240 1188 -2333 C ATOM 5336 O ARG F 340 33.361 -11.615 -66.587 1.00 67.34 O ANISOU 5336 O ARG F 340 9563 12392 3630 -132 1021 -2278 O ATOM 5337 N GLU F 341 32.949 -11.763 -68.797 1.00 72.62 N ANISOU 5337 N GLU F 341 10737 13286 3568 -315 1050 -2429 N ATOM 5338 CA GLU F 341 31.665 -12.460 -68.643 1.00 72.00 C ANISOU 5338 CA GLU F 341 10745 13030 3582 -280 699 -2511 C ATOM 5339 CB GLU F 341 30.833 -12.346 -69.924 1.00 75.35 C ANISOU 5339 CB GLU F 341 11521 13561 3548 -419 499 -2531 C ATOM 5340 CG GLU F 341 29.378 -12.802 -69.795 1.00 75.43 C ANISOU 5340 CG GLU F 341 11576 13430 3654 -432.

82. 2580 C ATOM 5341 CD GLU F 341 28.386 -11.646 -69.818 1.00 75.78 C ANISOU 5341 CD GLU F 341 11656 13495 3643 -509 -266 -2273 C ATOM 5342 OE1 GLU F 341 27.661 -11.539 -70.835 1.00 78.56 O ANISOU 5342 OE1 GLU F 341 12266 13948 3635 -593 -508 -2290 O ATOM 5343 OE2 GLU F 341 28.329 -10.858 -68.835 1.00 72.03 O ANISOU 5343 OE2 GLU F 341 10963 12933 3474 -469 -311 -2029 O ATOM 5344 C GLU F 341 31.866 -13.933 -68.254 1.00 72.08 C ANISOU 5344 C GLU F 341 10682 12885 3819 -116 781 -2838 C ATOM 5345 O GLU F 341 32.667 -14.650 -68.854 1.00 74.94 O ANISOU 5345 O GLU F 341 11113 13324 4035 -49 1050 -3099 O ATOM 5346 N GLU F 342 31.125 -14.370 -67.245 1.00 69.62 N ANISOU 5346 N GLU F 342 10251 12340 3862 -54 560 -2823 N ATOM 5347 CA GLU F 342 31.293 -15.693 -66.653 1.00 69.64 C ANISOU 5347 CA GLU F 342 10208 12126 4127 103 619 -3074 C ATOM 5348 CB GLU F 342 32.322 -15.633 -65.514 1.00 67.97 C ANISOU 5348 CB GLU F 342 9720 11849 4259 282 797 -3004 C ATOM 5349 CG GLU F 342 33.695 -16.187 -65.890 1.00 72.52 C ANISOU 5349 CG GLU F 342 10240 12529 4785 450 1138 -3236 C ATOM 5350 CD GLU F 342 34.866 -15.386 -65.320 1.00 73.01 C ANISOU 5350 CD GLU F 342 9998 12742 5001 520 1337 -3091 C ATOM 5351 OE1 GLU F 342 35.691 -14.915 -66.127 1.00 76.14 O ANISOU 5351 OE1 GLU F 342 10366 13400 5165 460 1597 -3130 O ATOM 5352 OE2 GLU F 342 34.977 -15.234 -64.084 1.00 71.41 O ANISOU 5352 OE2 GLU F 342 9591 12405 5135 615 1243 -2952 O ATOM 5353 C GLU F 342 29.962 -16.216 -66.134 1.00 67.95 C ANISOU 5353 C GLU F 342 10035 11683 4100 41 312 -3093 C ATOM 5354 O GLU F 342 29.181 -15.466 -65.550 1.00 65.42 O ANISOU 5354 O GLU F 342 9603 11333 3922 -40.

100. 2859 O ATOM 5355 N GLU F 343 29.706 -17.498 -66.380 1.00 69.90 N ANISOU 5355 N GLU F 343 10445 11769 4346 66 308 -3389 N ATOM 5356 CA GLU F 343 28.559 -18.194 -65.805 1.00 69.18 C ANISOU 5356 CA GLU F 343 10385 11429 4472 -16.

79. 3457 C ATOM 5357 CB GLU F 343 28.115 -19.373 -66.685 1.00 72.48 C ANISOU 5357 CB GLU F 343 11077 11759 4703 -93.

38. 3804 C ATOM 5358 CG GLU F 343 26.910 -19.055 -67.631 1.00 74.73 C ANISOU 5358 CG GLU F 343 11479 12200 4715 -329 -260 -3829 C ATOM 5359 CD GLU F 343 26.608 -20.312 -68.539 1.00 78.55 C ANISOU 5359 CD GLU F 343 12260 12593 4990 -414 -279 -4224 C ATOM 5360 OE1 GLU F 343 26.210 -21.396 -67.996 1.00 78.42 O ANISOU 5360 OE1 GLU F 343 12303 12280 5215 -445 -298 -4412 O ATOM 5361 OE2 GLU F 343 26.759 -20.210 -69.802 1.00 81.28 O ANISOU 5361 OE2 GLU F 343 12817 13155 4912 -468 -271 -4349 O ATOM 5362 C GLU F 343 28.962 -18.700 -64.434 1.00 66.86 C ANISOU 5362 C GLU F 343 9963 10869 4573 140 169 -3421 C ATOM 5363 O GLU F 343 30.023 -19.295 -64.287 1.00 68.01 O ANISOU 5363 O GLU F 343 10119 10944 4777 342 387 -3549 O ATOM 5364 N VAL F 344 28.126 -18.450 -63.434 1.00 64.55 N ANISOU 5364 N VAL F 344 9551 10437 4540 58 0 -3253 N ATOM 5365 CA VAL F 344 28.351 -18.977 -62.081 1.00 62.97 C ANISOU 5365 CA VAL F 344 9292 9954 4679 17.

57. 3208 C ATOM 5366 CB VAL F 344 28.623 -17.848 -61.021 1.00 59.59 C ANISOU 5366 CB VAL F 344 8616 9585 4440 22.

51. 2890 C ATOM 5367 CG1 VAL F 344 29.883 -17.084 -61.375 1.00 59.63 C ANISOU 5367 CG1 VAL F 344 8500 9834 4323 357 219 -2806 C ATOM 5368 CG2 VAL F 344 27.435 -16.885 -60.878 1.00 57.61 C ANISOU 5368 CG2 VAL F 344 8250 9422 4217.

29. 159 -2700 C ATOM 5369 C VAL F 344 27.175 -19.874 -61.683 1.00 63.62 C ANISOU 5369 C VAL F 344 9499 9764 491.

11.

81. 3328 C ATOM 5370 O VAL F 344 26.167 -19.933 -62.404 1.00 65.05 O ANISOU 5370 O VAL F 344 9736 10016 4963 -196 -243 -3431 O ATOM 5371 N LEU F 345 27.309 -20.581 -60.561 1.00 62.81 N ANISOU 5371 N LEU F 345 9450 9352 506.

92. 20 -3322 N ATOM 5372 CA LEU F 345 26.254 -21.491 -60.114 1.00 64.00 C ANISOU 5372 CA LEU F 345 9749 9208 5359 -98 -99 -3437 C ATOM 5373 CB LEU F 345 26.623 -22.938 -60.433 1.00 66.98 C

ANISOU 5373 CB LEU F 345 10440 9302 5705 -18.

4. 3726 C

ATOM 5374 CG LEU F 345 25.588 -24.015 -60.112 1.00 69.00 C

ANISOU 5374 CG LEU F 345 10916 9216 6083 -256 -48 -3887 C

ATOM 5375 CD1 LEU F 345 25.216 -24.820 -61.343 1.00 72.57 C

ANISOU 5375 CD1 LEU F 345 11584 9653 6334 -394 -85 -4220 C

ATOM 5376 CD2 LEU F 345 26.113 -24.915 -59.016 1.00 69.88 C

ANISOU 5376 CD2 LEU F 345 11247 8912 6394 -92.

72. 3866 C

ATOM 5377 C LEU F 345 25.911 -21.302 -58.632 1.00 61.95 C

ANISOU 5377 C LEU F 345 9405 8757 5376 -129 -105 -3225 C

ATOM 5378 O LEU F 345 26.775 -21.464 -57.754 1.00 61.11 O

ANISOU 5378 O LEU F 345 9333 8496 538.

83. 3 -3125 O

ATOM 5379 N THR F 346 24.649 -20.944 -58.369 1.00 61.45 N

ANISOU 5379 N THR F 346 9224 8720 5404 -389 -230 -3169 N

ATOM 5380 CA THR F 346 24.186 -20.634 -57.011 1.00 59.61 C

ANISOU 5380 CA THR F 346 8895 8347 5406 -459 -215 -2976 C

ATOM 5381 CB THR F 346 22.830 -19.857 -56.990 1.00 59.00 C

ANISOU 5381 CB THR F 346 8570 8441 5406 -711 -358 -2918 C

ATOM 5382 OG1 THR F 346 21.739 -20.769 -57.159 1.00 61.25 O

ANISOU 5382 OG1 THR F 346 8940 8578 5755 -989 -400 -3137 O

ATOM 5383 CG2 THR F 346 22.775 -18.783 -58.068 1.00 58.59 C

ANISOU 5383 CG2 THR F 346 8329 8761 5170 -678 -507 -2868 C

ATOM 5384 C THR F 346 24.058 -21.898 -56.162 1.00 61.14 C

ANISOU 5384 C THR F 346 9368 8119 5743 -514 -112 -3065 C

ATOM 5385 O THR F 346 24.144 -23.020 -56.681 1.00 64.20 O

ANISOU 5385 O THR F 346 10015 8309 6069 -530 -77 -3293 O

ATOM 5386 N GLY F 347 23.851 -21.703 -54.861 1.00 59.58 N

ANISOU 5386 N GLY F 347 9155 7768 5717 -548 -58 -2884 N

ATOM 5387 CA GLY F 347 23.695 -22.800 -53.910 1.00 61.10 C

ANISOU 5387 CA GLY F 347 9656 7535 6025 -620.

47. 2913 C

ATOM 5388 C GLY F 347 22.384 -23.558 -54.037 1.00 63.56 C

ANISOU 5388 C GLY F 347 10062 7682 6405 -1000.

56. 3100 C

ATOM 5389 O GLY F 347 22.088 -24.419 -53.209 1.00 65.10 O

ANISOU 5389 O GLY F 347 10531 7510 6694 -1136 166 -3112 O

ATOM 5390 N ASN F 348 21.594 -23.215 -55.055 1.00 64.06 N

ANISOU 5390 N ASN F 348 9904 8019 6416 -1185 -68 -3241 N

ATOM 5391 CA ASN F 348 20.382 -23.946 -55.409 1.00 66.83 C

ANISOU 5391 CA ASN F 348 10293 8274 6823 -1558 -97 -3477 C

ATOM 5392 CB ASN F 348 19.142 -23.043 -55.278 1.00 66.16 C

ANISOU 5392 CB ASN F 348 9806 8464 6867 -1802 -190 -3437 C

ATOM 5393 CG ASN F 348 17.840 -23.839 -55.092 1.00 69.65 C

ANISOU 5393 CG ASN F 348 10255 8745 7462 -2237 -149 -3647 C

ATOM 5394 OD1 ASN F 348 17.773 -24.763 -54.278 1.00 72.02 O

ANISOU 5394 OD1 ASN F 348 10853 8662 7850 -2387.

37. 3669 O

ATOM 5395 ND2 ASN F 348 16.799 -23.468 -55.839 1.00 69.91 N

ANISOU 5395 ND2 ASN F 348 9964 9072 7527 -2447 -330 -3802 N

ATOM 5396 C ASN F 348 20.544 -24.474 -56.834 1.00 69.06 C

ANISOU 5396 C ASN F 348 10684 8640 6915 -1547 -200 -3738 C

ATOM 5397 O ASN F 348 19.582 -24.911 -57.473 1.00 71.54 O

ANISOU 5397 O ASN F 348 10974 8984 7225 -1844 -293 -3970 O

ATOM 5398 N LEU F 349 21.791 -24.430 -57.308 1.00 68.36 N

ANISOU 5398 N LEU F 349 10708 8599 6666 -1207 -176 -3713 N

ATOM 5399 CA LEU F 349 22.186 -24.875 -58.655 1.00 70.41 C

ANISOU 5399 CA LEU F 349 11104 8949 6701 -1136 -228 -3954 C

ATOM 5400 CB LEU F 349 22.034 -26.402 -58.833 1.00 74.30 C

ANISOU 5400 CB LEU F 349 11995 9037 7197 -1269 -153 -4240 C

ATOM 5401 CG LEU F 349 23.212 -27.314 -58.448 1.00 75.35 C

ANISOU 5401 CG LEU F 349 12494 8800 7338 -960.

11. 4265 C

ATOM 5402 CD1 LEU F 349 23.480 -27.324 -56.942 1.00 73.43 C

ANISOU 5402 CD1 LEU F 349 12321 8288 7290 -860 111 -4005 C

ATOM 5403 CD2 LEU F 349 22.971 -28.730 -58.948 1.00 79.27 C

ANISOU 5403 CD2 LEU F 349 13395 8930 7794 -1104.

54. 4593 C

ATOM 5404 C LEU F 349 21.494 -24.087 -59.774 1.00 70.46 C

ANISOU 5404 C LEU F 349 10850 9370 6551 -1276 -435 -4021 C

ATOM 5405 O LEU F 349 21.080 -24.656 -60.785 1.00 73.71 O

ANISOU 5405 O LEU F 349 11378 9813 6815 -1431 -529 -4288 O

ATOM 5406 N GLN F 350 21.378 -22.778 -59.579 1.00 67.14 N

ANISOU 5406 N GLN F 350 10108 9250 6152 -1213 -519 -3778 N

ATOM 5407 CA GLN F 350 20.865 -21.888 -60.610 1.00 67.20 C

ANISOU 5407 CA GLN F 350 9898 9645 5989 -1271 -738 -3784 C

ATOM 5408 CB GLN F 350 19.977 -20.807 -59.982 1.00 65.17 C

ANISOU 5408 CB GLN F 350 9286 9560 5916 -1363 -855 -3582 C

ATOM 5409 CG GLN F 350 19.282 -19.897 -60.986 1.00 66.25 C

ANISOU 5409 CG GLN F 350 9203 10065 5904 -1411 -1134 -3582 C

ATOM 5410 CD GLN F 350 18.266 -18.962 -60.350 1.00 65.23 C

ANISOU 5410 CD GLN F 350 8713 10069 6003 -1493 -1259 -3436 C

ATOM 5411 OE1 GLN F 350 18.433 -18.500 -59.215 1.00 63.41 O

ANISOU 5411 OE1 GLN F 350 8380 9742 5972 -1419 -1115 -3235 O

ATOM 5412 NE2 GLN F 350 17.205 -18.670 -61.091 1.00 67.82 N

ANISOU 5412 NE2 GLN F 350 8845 10626 6297 -1630 -1540 -3552 N

ATOM 5413 C GLN F 350 22.031 -21.267 -61.393 1.00 66.19 C

ANISOU 5413 C GLN F 350 9811 9742 5597 -994 -707 -3697 C

ATOM 5414 O GLN F 350 23.053 -20.903 -60.811 1.00 63.73 O

ANISOU 5414 O GLN F 350 9487 9398 5327 -760 -551 -3513 O

ATOM 5415 N THR F 351 21.873 -21.162 -62.711 1.00 68.30 N

ANISOU 5415 N THR F 351 10130 10239 5581 -1042 -850 -3841 N

ATOM 5416 CA THR F 351 22.896 -20.578 -63.589 1.00 68.33 C

ANISOU 5416 CA THR F 351 10199 10477 5286 -837 -796 -3781 C

ATOM 5417 CB THR F 351 22.933 -21.313 -64.957 1.00 72.47 C

ANISOU 5417 CB THR F 351 10986 11065 5483 -903 -838 -4090 C

ATOM 5418 OG1 THR F 351 23.426 -22.645 -64.764 1.00 74.33 O

ANISOU 5418 OG1 THR F 351 11477 10978 5788 -858 -645 -4327 O

ATOM 5419 CG2 THR F 351 23.822 -20.584 -65.965 1.00 72.87 C

ANISOU 5419 CG2 THR F 351 11102 11406 5178 -749 -781 -4024 C

ATOM 5420 C THR F 351 22.726 -19.054 -63.781 1.00 66.46 C

ANISOU 5420 C THR F 351 9733 10556 4964 -796 -942 -3503 C

ATOM 5421 O THR F 351 21.670 -18.577 -64.223 1.00 67.46 O

ANISOU 5421 O THR F 351 9740 10849 5042 -941 -1208 -3500 O

ATOM 5422 N LEU F 352 23.774 -18.303 -63.438 1.00 63.82 N

ANISOU 5422 N LEU F 352 9338 10288 4622 -594 -780 -3279 N

ATOM 5423 CA LEU F 352 23.783 -16.849 -63.611 1.00 62.08 C

ANISOU 5423 CA LEU F 352 8962 10317 4309 -548 -879 -3005 C

ATOM 5424 CB LEU F 352 23.883 -16.122 -62.257 1.00 58.40 C

ANISOU 5424 CB LEU F 352 8278 9763 4150 -474 -815 -2744 C

ATOM 5425 CG LEU F 352 22.734 -16.210 -61.252 1.00 57.71 C

ANISOU 5425 CG LEU F 352 8017 9528 4381 -599 -923 -2723 C

ATOM 5426 CD1 LEU F 352 23.172 -15.633 -59.924 1.00 54.58 C

ANISOU 5426 CD1 LEU F 352 7487 9024 4226 -496 -788 -2494 C

ATOM 5427 CD2 LEU F 352 21.468 -15.522 -61.746 1.00 59.33 C

ANISOU 5427 CD2 LEU F 352 8065 9916 4561 -720 -1217 -2699 C

ATOM 5428 C LEU F 352 24.939 -16.408 -64.496 1.00 62.47 C

ANISOU 5428 C LEU F 352 9140 10557 4038 -426 -732 -2963 C

ATOM 5429 O LEU F 352 26.059 -16.914 -64.364 1.00 62.17 O

ANISOU 5429 O LEU F 352 9174 10448 4001 -291 -475 -3039 O

ATOM 5430 N LYS F 353 24.665 -15.457 -65.384 1.00 63.27 N

ANISOU 5430 N LYS F 353 9272 10900 3869 -470 -892 -2843 N

ATOM 5431 CA LYS F 353 25.722 -14.814 -66.150 1.00 64.14 C

ANISOU 5431 CA LYS F 353 9502 11201 3667 -397 -727 -2748 C

ATOM 5432 CB LYS F 353 25.257 -14.567 -67.589 1.00 67.60 C

ANISOU 5432 CB LYS F 353 10164 11852 3670 -499 -919 -2806 C

ATOM 5433 CG LYS F 353 26.308 -14.823 -68.681 1.00 70.46 C

ANISOU 5433 CG LYS F 353 10783 12357 3632 -480 -672 -2941 C

ATOM 5434 CD LYS F 353 25.734 -14.438 -70.067 1.00 74.26 C

ANISOU 5434 CD LYS F 353 11530 13051 3636 -595 -907 -2954 C

ATOM 5435 CE LYS F 353 26.582 -14.974 -71.227 1.00 78.07 C

ANISOU 5435 CE LYS F 353 12316 13659 3685 -614 -662 -3177 C

ATOM 5436 NZ LYS F 353 25.986 -14.635 -72.572 1.00 81.80 N

ANISOU 5436 NZ LYS F 353 13103 14333 3646 -737 -916 -3190 N

ATOM 5437 C LYS F 353 26.085 -13.500 -65.445 1.00 61.18 C

ANISOU 5437 C LYS F 353 8950 10869 3425 -333 -686 -2411 C ATOM 5438 O LYS F 353 25.259 -12.592 -65.346 1.00 60.54 O ANISOU 5438 O LYS F 353 8789 10834 3380 -374 -920 -2221 O ATOM 5439 N ILE F 354 27.308 -13.410 -64.930 1.00 59.64 N ANISOU 5439 N ILE F 354 8685 10652 3322 -226 -399 -2355 N ATOM 5440 CA ILE F 354 27.766 -12.181 -64.259 1.00 57.21 C ANISOU 5440 CA ILE F 354 8224 10380 3133 -191 -340 -2061 C ATOM 5441 CB ILE F 354 27.922 -12.336 -62.706 1.00 53.63 C ANISOU 5441 CB ILE F 354 7553 9725 3099 -105 -280 -1999 C ATOM 5442 CG1 ILE F 354 29.041 -13.330 -62.353 1.00 54.06 C ANISOU 5442 CG1 ILE F 354 7590 9699 325.

27.

30. 2177 C ATOM 5443 CD1 ILE F 354 29.514 -13.275 -60.917 1.00 51.17 C ANISOU 5443 CD1 ILE F 354 7045 9181 3215 13.

39. 2074 C ATOM 5444 CG2 ILE F 354 26.599 -12.724 -62.050 1.00 51.74 C ANISOU 5444 CG2 ILE F 354 7246 9318 3094 -161 -499 -2033 C ATOM 5445 C ILE F 354 29.064 -11.642 -64.869 1.00 58.84 C ANISOU 5445 C ILE F 354 8491 10766 3100 -178 -75 -2003 C ATOM 5446 O ILE F 354 29.891 -12.409 -65.373 1.00 60.22 O ANISOU 5446 O ILE F 354 8735 10998 3147 -131 148 -2215 O ATOM 5447 N ARG F 355 29.226 -10.318 -64.815 1.00 58.63 N ANISOU 5447 N ARG F 355 8438 10819 3021 -229 -85 -1728 N ATOM 5448 CA ARG F 355 30.437 -9.658 -65.305 1.00 60.49 C ANISOU 5448 CA ARG F 355 8713 11221 3050 -274 189 -1647 C ATOM 5449 CB ARG F 355 30.117 -8.263 -65.852 1.00 61.44 C ANISOU 5449 CB ARG F 355 8992 11418 2933 -394.

74. 1361 C ATOM 5450 CG ARG F 355 31.245 -7.634 -66.651 1.00 64.96 C ANISOU 5450 CG ARG F 355 9569 12047 3066 -511 373 -1292 C ATOM 5451 CD ARG F 355 30.886 -6.237 -67.160 1.00 66.33 C ANISOU 5451 CD ARG F 355 9972 12237 2992 -636 245 -979 C ATOM 5452 NE ARG F 355 30.037 -6.239 -68.360 1.00 71.70 N ANISOU 5452 NE ARG F 355 10987 12983 3272 -678.

11. 971 N ATOM 5453 CZ ARG F 355 29.472 -5.154 -68.895 1.00 73.47 C ANISOU 5453 CZ ARG F 355 11472 13191 3252 -738 -203 -704 C ATOM 5454 NH1 ARG F 355 29.634 -3.953 -68.346 1.00 73.36 N ANISOU 5454 NH1 ARG F 355 11440 13073 3362 -773 -196 -423 N ATOM 5455 NH2 ARG F 355 28.736 -5.268 -69.988 1.00 77.30 N ANISOU 5455 NH2 ARG F 355 12262 13752 3359 -754 -445 -722 N ATOM 5456 C ARG F 355 31.472 -9.601 -64.187 1.00 57.93 C ANISOU 5456 C ARG F 355 8122 10848 3041 -191 403 -1623 C ATOM 5457 O ARG F 355 31.365 -8.802 -63.252 1.00 55.72 O ANISOU 5457 O ARG F 355 7705 10480 2987 -196 329 -1419 O ATOM 5458 N VAL F 356 32.454 -10.488 -64.286 1.00 59.00 N ANISOU 5458 N VAL F 356 8187 11038 3193 -99 649 -1853 N ATOM 5459 CA VAL F 356 33.472 -10.669 -63.254 1.00 57.54 C ANISOU 5459 CA VAL F 356 7731 10818 3314 26 815 -1887 C ATOM 5460 CB VAL F 356 34.034 -12.124 -63.294 1.00 59.07 C ANISOU 5460 CB VAL F 356 7892 10969 3584 215 953 -2208 C ATOM 5461 CG1 VAL F 356 35.263 -12.285 -62.413 1.00 58.90 C ANISOU 5461 CG1 VAL F 356 7583 10962 3833 377 1122 -2261 C ATOM 5462 CG2 VAL F 356 32.959 -13.120 -62.889 1.00 58.12 C ANISOU 5462 CG2 VAL F 356 7884 10597 3601 282 725 -2309 C ATOM 5463 C VAL F 356 34.594 -9.647 -63.446 1.00 58.53 C ANISOU 5463 C VAL F 356 7742 11144 3352 -77 1059 -1769 C ATOM 5464 O VAL F 356 35.136 -9.510 -64.553 1.00 61.27 O ANISOU 5464 O VAL F 356 8201 11690 3390 -175 1273 -1838 O ATOM 5465 N HIS F 357 34.942 -8.926 -62.380 1.00 56.02 N ANISOU 5465 N HIS F 357 7219 10776 3291 -82 1041 -1603 N ATOM 5466 CA HIS F 357 36.060 -7.989 -62.470 1.00 57.30 C ANISOU 5466 CA HIS F 357 7240 11120 3411 -212 1281 -1516 C ATOM 5467 CB HIS F 357 35.754 -6.682 -61.737 1.00 55.20 C ANISOU 5467 CB HIS F 357 6955 10760 3259 -343 1148 -1222 C ATOM 5468 CG HIS F 357 34.762 -5.810 -62.460 1.00 56.04 C ANISOU 5468 CG HIS F 357 7368 10819 3105 -492 995 -1005 C ATOM 5469 ND1 HIS F 357 35.108 -4.564 -62.960 1.00 57.20 N ANISOU 5469 ND1 HIS F 357 7641 11040 3052 -709 1109 -802 N ATOM 5470 CE1 HIS F 357 34.034 -4.029 -63.539 1.00 57.73 C ANISOU 5470 CE1 HIS F 357 8005 11020 2910 -757 890 -629 C ATOM 5471 NE2 HIS F 357 33.002 -4.895 -63.453 1.00 56.73 N ANISOU 5471 NE2 HIS F 357 7904 10798 2853 -597 644 -736 N ATOM 5472 CD2 HIS F 357 33.429 -6.007 -62.764 1.00 55.77 C ANISOU 5472 CD2 HIS F 357 7539 10666 2984 -449 720 -964 C ATOM 5473 C HIS F 357 37.379 -8.623 -62.026 1.00 57.96 C ANISOU 5473 C HIS F 357 7008 11315 3698 -68 1502 -1730 C ATOM 5474 O HIS F 357 37.441 -9.312 -61.010 1.00 56.64 O ANISOU 5474 O HIS F 357 6685 11010 3825 136 1387 -1810 O ATOM 5475 N GLU F 358 38.424 -8.396 -62.813 1.00 60.88 N ANISOU 5475 N GLU F 358 7293 11938 3900 -169 1821 -1829 N ATOM 5476 CA GLU F 358 39.720 -9.030 -62.584 1.00 62.68 C ANISOU 5476 CA GLU F 358 7182 12324 4310 -13 2054 -2080 C ATOM 5477 CB GLU F 358 40.114 -9.904 -63.775 1.00 66.22 C ANISOU 5477 CB GLU F 358 7711 12931 4519 53 2310 -2364 C ATOM 5478 CG GLU F 358 39.357 -11.213 -63.855 1.00 66.22 C ANISOU 5478 CG GLU F 358 7904 12729 4529 286 2137 -2540 C ATOM 5479 CD GLU F 358 39.723 -12.027 -65.081 1.00 70.08 C ANISOU 5479 CD GLU F 358 8515 13362 4752 337 2398 -2837 C ATOM 5480 OE1 GLU F 358 40.884 -11.947 -65.532 1.00 73.92 O ANISOU 5480 OE1 GLU F 358 8787 14108 5193 324 2746 -3000 O ATOM 5481 OE2 GLU F 358 38.844 -12.747 -65.596 1.00 70.92 O ANISOU 5481 OE2 GLU F 358 8924 13330 4693 377 2265 -2927 O ATOM 5482 C GLU F 358 40.822 -8.024 -62.297 1.00 63.33 C ANISOU 5482 C GLU F 358 6971 12606 4485 -186 2258 -2010 C ATOM 5483 O GLU F 358 41.201 -7.245 -63.165 1.00 65.86 O ANISOU 5483 O GLU F 358 7365 13110 4550 -452 2506 -1950 O ATOM 5484 N GLY F 359 41.349 -8.079 -61.081 1.00 61.35 N ANISOU 5484 N GLY F 359 6404 12317 4590 -48 2153 -2027 N ATOM 5485 CA GLY F 359 42.408 -7.178 -60.650 1.00 62.41 C ANISOU 5485 CA GLY F 359 6211 12637 4866 -213 2303 -1990 C ATOM 5486 C GLY F 359 42.221 -6.774 -59.198 1.00 59.15 C ANISOU 5486 C GLY F 359 5681 12045 4748 -161 2011 -1834 C ATOM 5487 O GLY F 359 41.145 -6.954 -58.626 1.00 55.46 O ANISOU 5487 O GLY F 359 5438 11308 4326 -64 1725 -1700 O ATOM 5488 N TYR F 360 43.272 -6.231 -58.597 1.00 60.49 N ANISOU 5488 N TYR F 360 5491 12378 5116 -241 2091 -1868 N ATOM 5489 CA TYR F 360 43.140 -5.679 -57.274 1.00 58.50 C ANISOU 5489 CA TYR F 360 5160 11974 5092 -248 1830 -1716 C ATOM 5490 CB TYR F 360 44.441 -5.768 -56.483 1.00 61.17 C ANISOU 5490 CB TYR F 360 5016 12510 5718 -156 1845 -1890 C ATOM 5491 CG TYR F 360 44.405 -5.033 -55.139 1.00 60.37 C ANISOU 5491 CG TYR F 360 4845 12280 5811 -223 1588 -1737 C ATOM 5492 CD1 TYR F 360 44.129 -5.711 -53.941 1.00 57.83 C ANISOU 5492 CD1 TYR F 360 4525 11766 5682 75 1267 -1742 C ATOM 5493 CE1 TYR F 360 44.117 -5.040 -52.728 1.00 55.89 C ANISOU 5493 CE1 TYR F 360 4244 11416 5577 3 1045 -1619 C ATOM 5494 CZ TYR F 360 44.376 -3.669 -52.698 1.00 57.61 C ANISOU 5494 CZ TYR F 360 4417 11704 5768 -369 1137 -1499 C ATOM 5495 OH TYR F 360 44.375 -2.958 -51.515 1.00 56.33 O ANISOU 5495 OH TYR F 360 4240 11432 5729 -460 926 -1398 O ATOM 5496 CE2 TYR F 360 44.640 -2.979 -53.864 1.00 60.25 C ANISOU 5496 CE2 TYR F 360 4762 12201 5929 -672 1451 -1478 C ATOM 5497 CD2 TYR F 360 44.645 -3.656 -55.072 1.00 61.36 C ANISOU 5497 CD2 TYR F 360 4949 12461 5906 -601 1675 -1589 C ATOM 5498 C TYR F 360 42.675 -4.246 -57.382 1.00 57.20 C ANISOU 5498 C TYR F 360 5212 11733 4789 -608 1840 -1441 C ATOM 5499 O TYR F 360 43.193 -3.472 -58.181 1.00 59.56 O ANISOU 5499 O TYR F 360 5502 12205 4923 -901 2110 -1412 O ATOM 5500 N GLU F 361 41.695 -3.909 -56.553 1.00 53.97 N ANISOU 5500 N GLU F 361 5014 11047 4446 -581 1556 -1245 N ATOM 5501 CA GLU F 361 41.110 -2.579 -56.522 1.00 52.98 C ANISOU 5501 CA GLU F 361 5129 10781 4221 -857 1514 -981 C ATOM 5502 CB GLU F 361 39.809 -2.561 -57.329 1.00 51.91 C ANISOU 5502 CB GLU F 361 5403 10479 3840 -858 1435 -834 C ATOM 5503 CG GLU F 361 40.021 -2.601 -58.835 1.00 54.36 C ANISOU 5503 CG GLU F 361 5852 10968 3836 -989 1691 -875 C ATOM 5504 CD GLU F 361 38.780 -3.055 -59.586 1.00 54.79 C ANISOU 5504 CD GLU F 361 6252 10895 3671 -887 1552 -820 C ATOM 5505 OE1 GLU F 361 38.124 -4.047 -59.150 1.00 52.19 O ANISOU 5505 OE1 GLU F 361 5923 10445 3464 -635 1355 -913 O ATOM 5506 OE2 GLU F 361 38.474 -2.410 -60.614 1.00 54.98 O ANISOU 5506 OE2 GLU F 361 6559 10938 3391 -1074 1633 -684 O ATOM 5507 C GLU F 361 40.862 -2.085 -55.099 1.00 50.53 C ANISOU 5507 C GLU F 361 4782 10279 4137 -837 1267 -874 C ATOM 5508 O GLU F 361 40.743 -2.868 -54.158 1.00 48.99 O ANISOU 5508 O GLU F 361 4492 9997 4125 -585 1074 -955 O ATOM 5509 N GLU F 362 40.781 -0.769 -54.967 1.00 50.77 N ANISOU 5509 N GLU F 362 4930 10227 4132 -1111 1284 -690 N ATOM 5510 CA GLU F 362 40.569 -0.116 -53.696 1.00 49.49 C ANISOU 5510 CA GLU F 362 4773 9883 4149 -1141 1086 -593 C ATOM 5511 CB GLU F 362 41.853 0.602 -53.290 1.00 52.22 C ANISOU 5511 CB GLU F 362 4827 10402 4614 -1376 1204 -662 C ATOM 5512 CG GLU F 362 42.289 0.516 -51.833 1.00 53.76 C ANISOU 5512 CG GLU F 362 4795 10573 5058 -1278 995 -745 C ATOM 5513 CD GLU F 362 43.791 0.759 -51.700 1.00 59.82 C ANISOU 5513 CD GLU F 362 5136 11637 5954 -1447 1128 -920 C ATOM 5514 OE1 GLU F 362 44.203 1.943 -51.674 1.00 63.47 O ANISOU 5514 OE1 GLU F 362 5597 12108 6413 -1798 1232 -851 O ATOM 5515 OE2 GLU F 362 44.566 -0.232 -51.658 1.00 61.55 O ANISOU 5515 OE2 GLU F 362 5018 12080 6288 -1231 1134 -1137 O ATOM 5516 C GLU F 362 39.471 0.903 -53.950 1.00 47.93 C ANISOU 5516 C GLU F 362 4959 9439 3815 -1279 1021 -345 C ATOM 5517 O GLU F 362 39.619 1.764 -54.816 1.00 50.08 O ANISOU 5517 O GLU F 362 5385 9735 3909 -1529 1187 -230 O ATOM 5518 N PHE F 363 38.374 0.793 -53.206 1.00 44.53 N ANISOU 5518 N PHE F 363 4688 8767 3465 -1111 788 -267 N ATOM 5519 CA PHE F 363 37.236 1.684 -53.350 1.00 43.24 C ANISOU 5519 CA PHE F 363 4850 8361 3218 -1169 690 -58 C ATOM 5520 CB PHE F 363 35.981 0.878 -53.683 1.00 40.67 C ANISOU 5520 CB PHE F 363 4673 7941 2838 -939 548 -53 C ATOM 5521 CG PHE F 363 36.051 0.171 -54.979 1.00 40.68 C ANISOU 5521 CG PHE F 363 4709 8111 2635 -910 655 -120 C ATOM 5522 CD1 PHE F 363 35.670 0.807 -56.150 1.00 41.53 C ANISOU 5522 CD1 PHE F 363 5074 8214 2492 -1035 704 21 C ATOM 5523 CE1 PHE F 363 35.734 0.141 -57.373 1.00 42.89 C ANISOU 5523 CE1 PHE F 363 5312 8550 2433 -1019 806 -55 C ATOM 5524 CZ PHE F 363 36.189 -1.158 -57.422 1.00 42.89 C ANISOU 5524 CZ PHE F 363 5110 8707 2481 -871 874 -284 C ATOM 5525 CE2 PHE F 363 36.573 -1.800 -56.244 1.00 41.85 C ANISOU 5525 CE2 PHE F 363 4721 8557 2623 -723 816 -416 C ATOM 5526 CD2 PHE F 363 36.503 -1.134 -55.038 1.00 39.67 C ANISOU 5526 CD2 PHE F 363 4392 8132 2547 -749 702 -327 C ATOM 5527 C PHE F 363 36.925 2.473 -52.094 1.00 42.77 C ANISOU 5527 C PHE F 363 4840 8086 3327 -1199 550 18 C ATOM 5528 O PHE F 363 37.135 2.007 -50.973 1.00 41.83 O ANISOU 5528 O PHE F 363 4561 7954 3377 -1087 450 -85 O ATOM 5529 N THR F 364 36.389 3.667 -52.305 1.00 43.89 N ANISOU 5529 N THR F 364 5240 8037 3400 -1337 537 201 N ATOM 5530 CA THR F 364 35.644 4.393 -51.289 1.00 42.92 C ANISOU 5530 CA THR F 364 5254 7647 3406 -1303 388 282 C ATOM 5531 CB THR F 364 35.989 5.912 -51.391 1.00 45.24 C ANISOU 5531 CB THR F 364 5738 7796 3655 -1580 468 427 C ATOM 5532 OG1 THR F 364 36.808 6.290 -50.279 1.00 45.24 O ANISOU 5532 OG1 THR F 364 5587 7795 3810 -1716 475 338 O ATOM 5533 CG2 THR F 364 34.757 6.819 -51.449 1.00 46.04 C ANISOU 5533 CG2 THR F 364 6170 7588 3736 -1510 345 604 C ATOM 5534 C THR F 364 34.153 4.071 -51.527 1.00 41.58 C ANISOU 5534 C THR F 364 5252 7332 3215 -1076 236 345 C ATOM 5535 O THR F 364 33.686 4.150 -52.663 1.00 43.15 O ANISOU 5535 O THR F 364 5607 7543 3244 -1066 239 436 O ATOM 5536 N MSE F 365 33.435 3.668 -50.475 1.00 39.53 N ANISOU 5536 N MSE F 365 4952 6953 3115 -905 109 284 N ATOM 5537 CA MSE F 365 31.970 3.467 -50.514 1.00 38.74 C ANISOU 5537 CA MSE F 365 4959 6713 3047 -717 -25 317 C ATOM 5538 CB MSE F 365 31.558 2.102 -49.967 1.00 36.04 C ANISOU 5538 CB MSE F 365 4475 6423 2797 -544 -77 168 C ATOM 5539 CG MSE F 365 32.040 0.907 -50.754 1.00 36.93 C ANISOU 5539 CG MSE F 365 4478 6743 2812 -498 -25 64 C ATOM 5540 SE MSE F 365 31.519 -0.802 -49.939 0.90 39.05 SE ANISOU 5540 SE MSE F 365 4645 6991 3203 -298 -87 -113 SE ATOM 5541 CE MSE F 365 29.589 -0.577 -49.841 1.00 35.91 C ANISOU 5541 CE MSE F 365 4355 6406 2882 -215 -210 -68 C ATOM 5542 C MSE F 365 31.317 4.540 -49.661 1.00 37.78 C ANISOU 5542 C MSE F 365 4972 6339 3046 -712 -92 392 C ATOM 5543 O MSE F 365 31.692 4.733 -48.500 1.00 37.16 O ANISOU 5543 O MSE F 365 4845 6192 3080 -755 -78 332 O ATOM 5544 N VAL F 366 30.362 5.267 -50.226 1.00 38.03 N ANISOU 5544 N VAL F 366 5182 6223 3045 -647 -175 514 N ATOM 5545 CA VAL F 366 29.724 6.334 -49.460 1.00 38.03 C ANISOU 5545 CA VAL F 366 5316 5962 3171 -610 -229 570 C ATOM 5546 CB VAL F 366 30.225 7.753 -49.873 1.00 40.41 C ANISOU 5546 CB VAL F 366 5862 6104 3387 -782 -188 733 C ATOM 5547 CG1 VAL F 366 29.484 8.835 -49.096 1.00 40.76 C ANISOU 5547 CG1 VAL F 366 6072 5842 3573 -704 -250 771 C ATOM 5548 CG2 VAL F 366 31.728 7.887 -49.656 1.00 39.69 C ANISOU 5548 CG2 VAL F 366 5703 6126 3250 -1053 -37 699 C ATOM 5549 C VAL F 366 28.216 6.220 -49.565 1.00 37.81 C ANISOU 5549 C VAL F 366 5297 5841 3228 -377 -366 566 C ATOM 5550 O VAL F 366 27.635 6.467 -50.626 1.00 39.06 O ANISOU 5550 O VAL F 366 5559 5991 3289 -297 -470 667 O ATOM 5551 N GLY F 367 27.601 5.809 -48.458 1.00 36.34 N ANISOU 5551 N GLY F 367 4995 5600 3214 -276 -367 439 N ATOM 5552 CA GLY F 367 26.149 5.662 -48.373 1.00 35.97 C ANISOU 5552 CA GLY F 367 4885 5486 3296 -73 -463 389 C ATOM 5553 C GLY F 367 25.571 6.755 -47.502 1.00 37.01 C ANISOU 5553 C GLY F 367 5111 5371 3580 -2 -460 393 C ATOM 5554 O GLY F 367 26.298 7.648 -47.027 1.00 37.55 O ANISOU 5554 O GLY F 367 5332 5300 3634 -122 -397 444 O ATOM 5555 N LYS F 368 24.263 6.678 -47.289 1.00 37.07 N ANISOU 5555 N LYS F 368 5015 5327 3743 187 -521 315 N ATOM 5556 CA LYS F 368 23.522 7.707 -46.596 1.00 39.14 C ANISOU 5556 CA LYS F 368 5344 5357 4169 313 -519 293 C ATOM 5557 CB LYS F 368 22.035 7.565 -46.942 1.00 40.86 C ANISOU 5557 CB LYS F 368 5388 5594 4542 553 -639 224 C ATOM 5558 CG LYS F 368 21.244 8.827 -46.755 1.00 45.35 C ANISOU 5558 CG LYS F 368 6044 5921 5265 758 -706 244 C ATOM 5559 CD LYS F 368 20.322 9.053 -47.934 1.00 52.09 C ANISOU 5559 CD LYS F 368 6847 6803 6142 988 -956 316 C ATOM 5560 CE LYS F 368 21.070 9.688 -49.121 1.00 54.74 C ANISOU 5560 CE LYS F 368 7484 7077 6236 936 -1094 561 C ATOM 5561 NZ LYS F 368 20.132 10.022 -50.240 1.00 57.30 N ANISOU 5561 NZ LYS F 368 7821 7398 6554 1192 -1381 650 N ATOM 5562 C LYS F 368 23.751 7.641 -45.067 1.00 37.84 C ANISOU 5562 C LYS F 368 5174 5115 4090 229 -347 158 C ATOM 5563 O LYS F 368 23.754 8.670 -44.375 1.00 38.54 O ANISOU 5563 O LYS F 368 5412 4988 4245 237 -298 153 O ATOM 5564 N ARG F 369 23.945 6.421 -44.577 1.00 35.65 N ANISOU 5564 N ARG F 369 4759 4999 3789 150 -265 51 N ATOM 5565 CA ARG F 369 24.089 6.136 -43.170 1.00 35.10 C ANISOU 5565 CA ARG F 369 4704 4880 375.

76. 120 -72 C ATOM 5566 CB ARG F 369 22.839 5.418 -42.628 1.00 35.16 C ANISOU 5566 CB ARG F 369 4548 4914 3898 172 -37 -226 C ATOM 5567 CG ARG F 369 21.534 6.240 -42.641 1.00 36.78 C ANISOU 5567 CG ARG F 369 4677 4998 4298 364 -46 -284 C ATOM 5568 CD ARG F 369 20.626 5.893 -41.434 1.00 39.03 C ANISOU 5568 CD ARG F 369 4867 5249 4714 379 152 -479 C ATOM 5569 NE ARG F 369 20.476 7.016 -40.493 1.00 39.37 N ANISOU 5569 NE ARG F 369 5053 5078 4826 428 260 -540 N ATOM 5570 CZ ARG F 369 20.294 6.888 -39.186 1.00 41.20 C ANISOU 5570 CZ ARG F 369 5349 5245 5059 356 470 -682 C ATOM 5571 NH1 ARG F 369 20.260 5.688 -38.625 1.00 40.27 N ANISOU 5571 NH1 ARG F 369 5187 5244 4870 225 594 -756 N ATOM 5572 NH2 ARG F 369 20.172 7.967 -38.423 1.00 45.93 N ANISOU 5572 NH2 ARG F 369 6100 5643 5708 408 562 -750 N ATOM 5573 C ARG F 369 25.349 5.297 -42.903 1.00 33.83 C ANISOU 5573 C ARG F 369 4557 4853 3444 -89 -92 -70 C ATOM 5574 O ARG F 369 25.582 4.876 -41.779 1.00 33.68 O ANISOU 5574 O ARG F 369 4575 4816 3407 -150 -7 -158 O ATOM 5575 N ALA F 370 26.165 5.072 -43.928 1.00 33.74 N ANISOU 5575 N ALA F 370 4525 4977 3319 -148 -165 25 N ATOM 5576 CA ALA F 370 27.433 4.376 -43.756 1.00 33.32 C ANISOU 5576 CA ALA F 370 4448 5061 3152 -271 -149 14 C ATOM 5577 CB ALA F 370 27.219 2.866 -43.786 1.00 32.53 C ANISOU 5577 CB ALA F 370 4229 5094 3036 -219 -139 -68 C ATOM 5578 C ALA F 370 28.480 4.805 -44.796 1.00 34.46 C ANISOU 5578 C ALA F 370 4607 5301 3186 -377 -183 124 C ATOM 5579 O ALA F 370 28.141 5.420 -45.821 1.00 35.44 O ANISOU 5579 O ALA F 370 4786 5396 3282 -351 -228 227 O ATOM 5580 N THR F 371 29.749 4.533 -44.485 1.00 34.41 N ANISOU 5580 N THR F 371 4557 5404 3113 -500 -162 97 N ATOM 5581 CA THR F 371 30.877 4.693 -45.401 1.00 35.72 C ANISOU 5581 CA THR F 371 4675 5719 3179 -628 -147 157 C ATOM 5582 CB THR F 371 31.658 6.063 -45.259 1.00 37.27 C ANISOU 5582 CB THR F 371 4983 5816 3361 -831 -115 222 C ATOM 5583 OG1 THR F 371 32.299 6.139 -43.983 1.00 39.27 O ANISOU 5583 OG1 THR F 371 5217 6048 3656 -912 -125 125 O ATOM 5584 CG2 THR F 371 30.771 7.277 -45.436 1.00 38.77 C ANISOU 5584 CG2 THR F 371 5387 5755 3590 -806 -128 324 C ATOM 5585 C THR F 371 31.864 3.567 -45.105 1.00 35.06 C ANISOU 5585 C THR F 371 4426 5831 3065 -633 -144 55 C ATOM 5586 O THR F 371 31.992 3.125 -43.961 1.00 34.68 O ANISOU 5586 O THR F 371 4370 5753 3055 -598 -175 -28 O ATOM 5587 N ALA F 372 32.582 3.125 -46.131 1.00 35.32 N ANISOU 5587 N ALA F 372 4346 6058 3017 -666 -110 60 N ATOM 5588 CA ALA F 372 33.520 2.019 -45.996 1.00 34.84 C ANISOU 5588 CA ALA F 372 4107 6186 2944 -621 -112 -50 C ATOM 5589 CB ALA F 372 32.796 0.677 -46.224 1.00 33.58 C ANISOU 5589 CB ALA F 372 3933 6046 2781 -434 -136 -111 C ATOM 5590 C ALA F 372 34.709 2.162 -46.952 1.00 36.35 C ANISOU 5590 C ALA F 372 4157 6590 3064 -749 -55 C ATOM 5591 O ALA F 372 34.637 2.846 -47.979 1.00 37.00 O ANISOU 5591 O ALA F 372 4314 6683 3060 -860 51 41 O ATOM 5592 N ILE F 373 35.809 1.530 -46.579 1.00 36.90 N ANISOU 5592 N ILE F 373 4028 6828 3166 -731 -172 N ATOM 5593 CA ILE F 373 36.920 1.327 -47.482 1.00 38.46 C ANISOU 5593 CA ILE F 373 4023 7274 3317 -805.

74. 232 C ATOM 5594 CB ILE F 373 38.271 1.774 -46.878 1.00 40.52 C ANISOU 5594 CB ILE F 373 4067 7677 3652 -954.

71. 316 C ATOM 5595 CG1 ILE F 373 38.285 3.292 -46.705 1.00 41.82 C ANISOU 5595 CG1 ILE F 373 4365 7713 3813 -1228 112 -214 C ATOM 5596 CD1 ILE F 373 38.951 3.744 -45.409 1.00 46.04 C ANISOU 5596 CD1 ILE F 373 4819 8231 4445 -1323 -5 -292 C ATOM 5597 CG2 ILE F 373 39.438 1.353 -47.777 1.00 42.20 C ANISOU 5597 CG2 ILE F 373 3998 8188 3847 -998 208 -427 C ATOM 5598 C ILE F 373 36.917 -0.152 -47.827 1.00 37.80 C ANISOU 5598 C ILE F 373 3843 7296 3223 -576.

62. 341 C ATOM 5599 O ILE F 373 37.018 -1.025 -46.943 1.00 36.27 O ANISOU 5599 O ILE F 373 3606 7073 3101 -402 -52 -425 O ATOM 5600 N LEU F 374 36.771 -0.409 -49.125 1.00 37.99 N ANISOU 5600 N LEU F 374 3882 7418 3136 -580 175 -333 N ATOM 5601 CA LEU F 374 36.835 -1.740 -49.675 1.00 37.72 C ANISOU 5601 CA LEU F 374 3776 7485 3070 -391 197 -455 C ATOM 5602 CB LEU F 374 35.600 -2.008 -50.541 1.00 36.81 C ANISOU 5602 CB LEU F 374 3865 7278 2844 -346 196 -396 C ATOM 5603 CG LEU F 374 35.410 -3.409 -51.127 1.00 35.70 C ANISOU 5603 CG LEU F 374 3719 7187 2659 -167 206 -529 C ATOM 5604 CD1 LEU F 374 35.355 -4.482 -50.037 1.00 32.88 C ANISOU 5604 CD1 LEU F 374 3345 6714 2434 2.

94. 622 C ATOM 5605 CD2 LEU F 374 34.154 -3.412 -51.980 1.00 36.04 C ANISOU 5605 CD2 LEU F 374 3956 7151 2586 -180 174 -465 C ATOM 5606 C LEU F 374 38.114 -1.935 -50.495 1.00 40.40 C ANISOU 5606 C LEU F 374 3881 8101 3369 -441 359 -571 C ATOM 5607 O LEU F 374 38.330 -1.244 -51.491 1.00 41.59 O ANISOU 5607 O LEU F 374 4056 8354 3393 -631 516 -515 O ATOM 5608 N ARG F 375 38.958 -2.863 -50.040 1.00 41.39 N ANISOU 5608 N ARG F 375 3788 8340 3600 -264 322 -734 N ATOM 5609 CA ARG F 375 40.081 -3.367 -50.817 1.00 44.76 C ANISOU 5609 CA ARG F 375 3954 9037 4017 -227 480 -901 C ATOM 5610 CB ARG F 375 41.365 -3.461 -49.975 1.00 46.06 C ANISOU 5610 CB ARG F 375 3782 9363 4356 -167 416 -1037 C ATOM 5611 CG ARG F 375 41.765 -2.160 -49.277 1.00 47.35 C ANISOU 5611 CG ARG F 375 3874 9536 4580 -429 379 -955 C ATOM 5612 CD ARG F 375 43.214 -2.192 -48.753 1.00 51.18 C ANISOU 5612 CD ARG F 375 3943 10275 5227 -420 344 -1131 C ATOM 5613 NE ARG F 375 43.464 -1.175 -47.726 1.00 56.01 N ANISOU 5613 NE ARG F 375 4529 10837 5914 -618 213 -1075 N ATOM 5614 CZ ARG F 375 44.650 -0.608 -47.469 1.00 59.99 C ANISOU 5614 CZ ARG F 375 4690 11572 6531 -795 230 -1192 C ATOM 5615 NH1 ARG F 375 45.730 -0.928 -48.175 1.00 63.23 N ANISOU 5615 NH1 ARG F 375 4713 12304 7009 -801 399 -1375 N ATOM 5616 NH2 ARG F 375 44.757 0.294 -46.496 1.00 61.29 N ANISOU 5616 NH2 ARG F 375 4888 11655 6746 -981.

88. 1145 N ATOM 5617 C ARG F 375 39.650 -4.740 -51.345 1.00 44.39 C ANISOU 5617 C ARG F 375 3991 8951 3922 26 478 -1009 C ATOM 5618 O ARG F 375 39.022 -5.515 -50.620 1.00 42.96 O ANISOU 5618 O ARG F 375 3945 8574 3804 217 312 -1010 O ATOM 5619 N LYS F 376 39.987 -5.036 -52.600 1.00 46.26 N ANISOU 5619 N LYS F 376 4176 9365 4035 5 679 -1106 N ATOM 5620 CA LYS F 376 39.348 -6.134 -53.320 1.00 46.24 C ANISOU 5620 CA LYS F 376 4340 9297 3933 173 694 -1190 C ATOM 5621 CB LYS F 376 38.040 -5.601 -53.905 1.00 45.02 C ANISOU 5621 CB LYS F 376 4494 9002 3608 21 666 -1020 C ATOM 5622 CG LYS F 376 37.218 -6.592 -54.639 1.00 45.84 C ANISOU 5622 CG LYS F 376 4788 9030 3597 138 648 -1099 C ATOM 5623 CD LYS F 376 36.312 -5.902 -55.630 1.00 45.93 C ANISOU 5623 CD LYS F 376 5028 9033 3391 -41 662 -965 C ATOM 5624 CE LYS F 376 35.659 -6.942 -56.497 1.00 47.28 C ANISOU 5624 CE LYS F 376 5357 9181 3425 56 651 -1090 C ATOM 5625 NZ LYS F 376 36.674 -7.533 -57.410 1.00 49.17 N ANISOU 5625 NZ LYS F 376 5499 9636 3547 101 872 -1286 N ATOM 5626 C LYS F 376 40.212 -6.718 -54.445 1.00 49.04 C ANISOU 5626 C LYS F 376 4537 9897 4199 227 926 -1392 C ATOM 5627 O LYS F 376 40.914 -5.980 -55.142 1.00 51.37 O ANISOU 5627 O LYS F 376 4701 10414 4403 20 1140 -1400 O ATOM 5628 N ALA F 377 40.148 -8.041 -54.624 1.00 48.89 N ANISOU 5628 N ALA F 377 4554 9824 4200 490 905 -1564 N ATOM 5629 CA ALA F 377 40.819 -8.718 -55.746 1.00 50.86 C ANISOU 5629 CA ALA F 377 4702 10273 4349 573 1136 -1786 C ATOM 5630 CB ALA F 377 41.903 -9.649 -55.227 1.00 53.08 C ANISOU 5630 CB ALA F 377 4691 10631 4845 884 1125 -2013 C ATOM 5631 C ALA F 377 39.807 -9.480 -56.625 1.00 50.17 C ANISOU 5631 C ALA F 377 4938 10055 4069 617 1139 -1830 C ATOM 5632 O ALA F 377 38.594 -9.335 -56.445 1.00 47.07 O ANISOU 5632 O ALA F 377 4807 9454 3625 543 972 -1675 O ATOM 5633 N THR F 378 40.302 -10.282 -57.575 1.00 52.64 N ANISOU 5633 N THR F 378 5218 10501 4283 731 1331 -2062 N ATOM 5634 CA THR F 378 39.443 -11.109 -58.447 1.00 52.30 C ANISOU 5634 CA THR F 378 5480 10344 4050 774 1333 -2154 C ATOM 5635 CB THR F 378 40.261 -11.862 -59.508 1.00 56.31 C ANISOU 5635 CB THR F 378 5911 11045 4441 890 1603 -2444 C ATOM 5636 OG1 THR F 378 41.023 -10.926 -60.282 1.00 58.56 O ANISOU 5636 OG1 THR F 378 6043 11640 4566 661 1879 -2434 O ATOM 5637 CG2 THR F 378 39.345 -12.685 -60.420 1.00 56.32 C ANISOU 5637 CG2 THR F 378 6258 10920 4219 905 1590 -2552 C ATOM 5638 C THR F 378 38.624 -12.111 -57.623 1.00 50.10 C ANISOU 5638 C THR F 378 5380 9738 3920 974 1085 -2166 C ATOM 5639 O THR F 378 39.174 -13.029 -57.010 1.00 50.63 O ANISOU 5639 O THR F 378 5354 9711 4174 1249 1041 -2309 O ATOM 5640 N ARG F 379 37.307 -11.917 -57.630 1.00 47.53 N ANISOU 5640 N ARG F 379 5314 9237 3507 831 928 -2016 N ATOM 5641 CA ARG F 379 36.375 -12.691 -56.812 1.00 45.98 C ANISOU 5641 CA ARG F 379 5299 8730 3442 929 717 -1996 C ATOM 5642 CB ARG F 379 35.991 -13.986 -57.509 1.00 47.10 C ANISOU 5642 CB ARG F 379 5649 8750 3497 1039 741 -2218 C ATOM 5643 CG ARG F 379 35.553 -13.795 -58.975 1.00 49.36 C ANISOU 5643 CG ARG F 379 6077 9194 3483 864 839 -2280 C ATOM 5644 CD ARG F 379 34.872 -15.036 -59.519 1.00 49.19 C ANISOU 5644 CD ARG F 379 6310 8999 3381 920 800 -2486 C ATOM 5645 NE ARG F 379 33.688 -15.336 -58.716 1.00 48.20 N ANISOU 5645 NE ARG F 379 6327 8598 3390 864 582 -2392 N ATOM 5646 CZ ARG F 379 32.926 -16.417 -58.847 1.00 48.36 C ANISOU 5646 CZ ARG F 379 6569 8396 3409 870 509 -2542 C ATOM 5647 NH1 ARG F 379 33.204 -17.326 -59.776 1.00 50.81 N ANISOU 5647 NH1 ARG F 379 7015 8710 3582 951 618 -2802 N ATOM 5648 NH2 ARG F 379 31.886 -16.587 -58.042 1.00 43.85 N ANISOU 5648 NH2 ARG F 379 6090 7596 2976 779 346 -2448 N ATOM 5649 C ARG F 379 36.840 -12.931 -55.347 1.00 45.52 C ANISOU 5649 C ARG F 379 5126 8523 3646 1110 592 -1952 C ATOM 5650 O ARG F 379 36.679 -14.029 -54.799 1.00 46.28 O ANISOU 5650 O ARG F 379 5352 8383 3849 1302 501 -2041 O ATOM 5651 N ARG F 380 37.400 -11.897 -54.717 1.00 44.64 N ANISOU 5651 N ARG F 380 4807 8534 3618 1036 579 -1811 N ATOM 5652 CA ARG F 380 37.835 -11.998 -53.324 1.00 44.23 C ANISOU 5652 CA ARG F 380 4663 8367 3777 1184 430 -1758 C ATOM 5653 CB ARG F 380 39.209 -12.663 -53.248 1.00 47.80 C ANISOU 5653 CB ARG F 380 4876 8940 4345 1461 483 -1956 C ATOM 5654 CG ARG F 380 39.793 -12.813 -51.838 1.00 49.84 C ANISOU 5654 CG ARG F 380 5033 9103 4802 1655 286 -1915 C ATOM 5655 CD ARG F 380 41.062 -13.651 -51.917 1.00 56.80 C ANISOU 5655 CD ARG F 380 5680 10096 5807 1991 313 -2147 C ATOM 5656 NE ARG F 380 42.171 -13.087 -51.147 1.00 61.43 N ANISOU 5656 NE ARG F 380 5917 10875 6548 2062 223 -2147 N ATOM 5657 CZ ARG F 380 43.388 -12.828 -51.635 1.00 64.11 C ANISOU 5657 CZ ARG F 380 5845 11552 6964 2111 368 -2317 C ATOM 5658 NH1 ARG F 380 43.677 -13.067 -52.908 1.00 65.91 N ANISOU 5658 NH1 ARG F 380 5980 11960 7104 2099 641 -2496 N ATOM 5659 NH2 ARG F 380 44.326 -12.326 -50.842 1.00 65.00 N ANISOU 5659 NH2 ARG F 380 5629 11835 7234 2157 247 -2324 N ATOM 5660 C ARG F 380 37.852 -10.660 -52.621 1.00 41.88 C ANISOU 5660 C ARG F 380 4256 8133 3523 993 370 -1553 C ATOM 5661 O ARG F 380 38.517 -9.734 -53.075 1.00 42.95 O ANISOU 5661 O ARG F 380 4196 8508 3614 848 494 -1530 O ATOM 5662 N LEU F 381 37.099 -10.574 -51.519 1.00 39.44 N ANISOU 5662 N LEU F 381 4100 7595 3292 975 200 -1415 N ATOM 5663 CA LEU F 381 37.138 -9.447 -50.574 1.00 37.48 C ANISOU 5663 CA LEU F 381 3781 7350 3109 840 116 -1247 C ATOM 5664 CB LEU F 381 35.919 -9.479 -49.643 1.00 35.32 C ANISOU 5664 CB LEU F 381 3754 6800 2866 791 -16 -1118 C ATOM 5665 CG LEU F 381 35.557 -8.300 -48.733 1.00 33.09 C ANISOU 5665 CG LEU F 381 3486 6465 2620 628 -85 -947 C ATOM 5666 CD1 LEU F 381 34.028 -8.185 -48.630 1.00 28.32 C ANISOU 5666 CD1 LEU F 381 3096 5671 1992 513 -108 -858 C ATOM 5667 CD2 LEU F 381 36.185 -8.462 -47.322 1.00 32.20 C ANISOU 5667 CD2 LEU F 381 3358 6270 2605 750 -225 -936 C ATOM 5668 C LEU F 381 38.412 -9.549 -49.763 1.00 38.85 C ANISOU 5668 C LEU F 381 3730 7616 3415 100.

44. 1313 C ATOM 5669 O LEU F 381 38.661 -10.569 -49.124 1.00 39.13 O ANISOU 5669 O LEU F 381 3822 7515 3530 1250 -72 -1389 O ATOM 5670 N VAL F 382 39.229 -8.500 -49.829 1.00 39.49 N ANISOU 5670 N VAL F 382 3562 7926 3518 858 106 -1289 N ATOM 5671 CA VAL F 382 40.512 -8.475 -49.144 1.00 41.58 C ANISOU 5671 CA VAL F 382 3538 8340 3920 98.

28. 1378 C ATOM 5672 CB VAL F 382 41.603 -7.708 -49.966 1.00 43.41 C ANISOU 5672 CB VAL F 382 3420 8920 4155 821 228 -1467 C ATOM 5673 CG1 VAL F 382 42.891 -7.551 -49.173 1.00 44.97 C ANISOU 5673 CG1 VAL F 382 3263 9301 4525 909 121 -1569 C ATOM 5674 CG2 VAL F 382 41.887 -8.422 -51.295 1.00 45.12 C ANISOU 5674 CG2 VAL F 382 3569 9282 4293 909 448 -1638 C ATOM 5675 C VAL F 382 40.312 -7.883 -47.743 1.00 40.72 C ANISOU 5675 C VAL F 382 3510 8092 3870 921 -175 -1239 C ATOM 5676 O VAL F 382 40.756 -8.472 -46.752 1.00 41.67 O ANISOU 5676 O VAL F 382 3618 8139 4075 1138 -368 -1279 O ATOM 5677 N GLN F 383 39.620 -6.740 -47.677 1.00 39.32 N ANISOU 5677 N GLN F 383 3446 7862 3630 645 -138 -1080 N ATOM 5678 CA GLN F 383 39.373 -6.002 -46.438 1.00 38.54 C ANISOU 5678 CA GLN F 383 3444 7637 3564 546 -287 -961 C ATOM 5679 CB GLN F 383 40.628 -5.223 -46.012 1.00 40.51 C ANISOU 5679 CB GLN F 383 3390 8104 3898 455 -334 -1014 C ATOM 5680 CG GLN F 383 40.645 -4.744 -44.547 1.00 40.45 C ANISOU 5680 CG GLN F 383 3469 7978 3921 423 -545 -949 C ATOM 5681 CD GLN F 383 41.875 -3.885 -44.209 1.00 43.46 C ANISOU 5681 CD GLN F 383 3531 8595 4388 279 -598 -1023 C ATOM 5682 OE1 GLN F 383 42.401 -3.158 -45.063 1.00 47.32 O ANISOU 5682 OE1 GLN F 383 3803 9284 489.

65. 416 -1057 O ATOM 5683 NE2 GLN F 383 42.331 -3.969 -42.958 1.00 43.22 N ANISOU 5683 NE2 GLN F 383 3486 8538 4398 376 -848 -1052 N ATOM 5684 C GLN F 383 38.227 -5.022 -46.652 1.00 36.57 C ANISOU 5684 C GLN F 383 3400 7259 3236 306 -212 -801 C ATOM 5685 O GLN F 383 38.119 -4.405 -47.720 1.00 37.21 O ANISOU 5685 O GLN F 383 3447 7443 3248 144 -58 -768 O ATOM 5686 N LEU F 384 37.369 -4.907 -45.642 1.00 34.97 N ANISOU 5686 N LEU F 384 3425 6828 3036 299 -318 -709 N ATOM 5687 CA LEU F 384 36.306 -3.912 -45.594 1.00 33.66 C ANISOU 5687 CA LEU F 384 3428 6527 2834 111 -275 -576 C ATOM 5688 CB LEU F 384 34.924 -4.535 -45.873 1.00 31.81 C ANISOU 5688 CB LEU F 384 3403 6118 2566 163 -248 -546 C ATOM 5689 CG LEU F 384 33.659 -3.661 -45.748 1.00 30.14 C ANISOU 5689 CG LEU F 384 3344 5757 235.

32. 224 -435 C ATOM 5690 CD1 LEU F 384 33.439 -2.719 -46.929 1.00 25.61 C ANISOU 5690 CD1 LEU F 384 2737 5271 1724 -100 -144 -364 C ATOM 5691 CD2 LEU F 384 32.413 -4.513 -45.509 1.00 29.87 C ANISOU 5691 CD2 LEU F 384 3472 5546 2330 101 -229 -452 C ATOM 5692 C LEU F 384 36.364 -3.301 -44.207 1.00 33.92 C ANISOU 5692 C LEU F 384 3539 6450 290.

56. 390 -531 C ATOM 5693 O LEU F 384 36.411 -4.017 -43.192 1.00 34.45 O ANISOU 5693 O LEU F 384 3703 6414 2973 195 -514 -559 O ATOM 5694 N ILE F 385 36.419 -1.976 -44.173 1.00 34.62 N ANISOU 5694 N ILE F 385 3612 6550 2992 -150 -352 -464 N ATOM 5695 CA ILE F 385 36.450 -1.228 -42.930 1.00 35.04 C ANISOU 5695 CA ILE F 385 3759 6494 3061 -238 -445 -436 C ATOM 5696 CB ILE F 385 37.718 -0.361 -42.822 1.00 36.95 C ANISOU 5696 CB ILE F 385 3794 6908 3338 -401 -473 -480 C ATOM 5697 CG1 ILE F 385 38.985 -1.211 -43.001 1.00 38.55 C ANISOU 5697 CG1 ILE F 385 3710 7352 3587 -268 -538 -611 C ATOM 5698 CD1 ILE F 385 40.287 -0.384 -43.171 1.00 41.49 C ANISOU 5698 CD1 ILE F 385 3783 7960 4019 -466 -520 -687 C ATOM 5699 CG2 ILE F 385 37.746 0.385 -41.474 1.00 37.52 C ANISOU 5699 CG2 ILE F 385 3994 6855 3407 -499 -592 -475 C ATOM 5700 C ILE F 385 35.213 -0.350 -42.996 1.00 34.38 C ANISOU 5700 C ILE F 385 3874 6223 2965 -350 -364 -332 C ATOM 5701 O ILE F 385 35.148 0.522 -43.864 1.00 35.97 O ANISOU 5701 O ILE F 385 4050 6456 3159 -485 -273 -270 O ATOM 5702 N VAL F 386 34.230 -0.603 -42.119 1.00 32.76 N ANISOU 5702 N VAL F 386 3871 5822 2755 -286 -389 -317 N ATOM 5703 CA VAL F 386 32.929 0.098 -42.139 1.00 31.18 C ANISOU 5703 CA VAL F 386 3822 5448 2576 -341 -310 -251 C ATOM 5704 CB VAL F 386 31.707 -0.895 -42.196 1.00 30.22 C ANISOU 5704 CB VAL F 386 3791 5226 2465 -223 -267 -266 C ATOM 5705 CG1 VAL F 386 30.411 -0.170 -42.554 1.00 28.82 C ANISOU 5705 CG1 VAL F 386 3669 4938 2344 -255 -195 -220 C ATOM 5706 CG2 VAL F 386 31.928 -2.001 -43.194 1.00 31.56 C ANISOU 5706 CG2 VAL F 386 3858 5519 2615 -125 -265 -303 C ATOM 5707 C VAL F 386 32.736 1.020 -40.921 1.00 31.34 C ANISOU 5707 C VAL F 386 3995 5314 2601 -430 -328 -248 C ATOM 5708 O VAL F 386 33.123 0.664 -39.792 1.00 31.29 O ANISOU 5708 O VAL F 386 4065 5275 2548 -406 -407 -298 O ATOM 5709 N SER F 387 32.167 2.205 -41.181 1.00 30.66 N ANISOU 5709 N SER F 387 3973 5122 2554 -523 -264 -192 N ATOM 5710 CA SER F 387 31.593 3.089 -40.168 1.00 30.93 C ANISOU 5710 CA SER F 387 4185 4961 2606 -577 -238 -204 C ATOM 5711 CB SER F 387 32.314 4.437 -40.147 1.00 32.15 C ANISOU 5711 CB SER F 387 4367 5081 2766 -752 -252 -182 C ATOM 5712 OG SER F 387 33.719 4.299 -40.027 1.00 33.45 O ANISOU 5712 OG SER F 387 4399 5419 2892 -849 -338 -224 O ATOM 5713 C SER F 387 30.123 3.319 -40.541 1.00 30.20 C ANISOU 5713 C SER F 387 4150 4737 2589 -496 -148 -176 C ATOM 5714 O SER F 387 29.797 3.411 -41.720 1.00 30.80 O ANISOU 5714 O SER F 387 4146 4862 2693 -463 -140 -113 O ATOM 5715 N GLY F 388 29.239 3.409 -39.556 1.00 29.35 N ANISOU 5715 N GLY F 388 4170 4476 2507 -463 -82 -233 N ATOM 5716 CA GLY F 388 27.829 3.707 -39.816 1.00 28.50 C ANISOU 5716 CA GLY F 388 4063 4258 2506 -376.

4. 240 C ATOM 5717 C GLY F 388 27.081 4.361 -38.647 1.00 28.60 C ANISOU 5717 C GLY F 388 4224 4084 2558 -377 109 -322 C ATOM 5718 O GLY F 388 27.550 4.343 -37.526 1.00 27.72 O ANISOU 5718 O GLY F 388 4253 3926 2354 -450 122 -378 O ATOM 5719 N LYS F 389 25.894 4.911 -38.914 1.00 28.96 N ANISOU 5719 N LYS F 389 4235 4030 2737 -281 179 -343 N ATOM 5720 CA LYS F 389 25.150 5.640 -37.881 1.00 30.12 C ANISOU 5720 CA LYS F 389 4504 3998 2943 -260 308 -446 C ATOM 5721 CB LYS F 389 24.270 6.732 -38.500 1.00 31.54 C ANISOU 5721 CB LYS F 389 4640 4054 3289 -128 310 -434 C ATOM 5722 CG LYS F 389 25.065 7.735 -39.311 1.00 31.37 C ANISOU 5722 CG LYS F 389 4699 3977 3246 -167 180 -301 C ATOM 5723 CD LYS F 389 24.164 8.721 -39.993 1.00 32.90 C ANISOU 5723 CD LYS F 389 4890 4023 3587 1 146 -263 C ATOM 5724 CE LYS F 389 24.971 9.802 -40.644 1.00 33.28 C ANISOU 5724 CE LYS F 389 5107 3953 3584 -75.

49. 123 C ATOM 5725 NZ LYS F 389 24.087 10.800 -41.284 1.00 36.05 N ANISOU 5725 NZ LYS F 389 5517 4114 4065 121 -12 -67 N ATOM 5726 C LYS F 389 24.345 4.720 -36.971 1.00 30.25 C ANISOU 5726 C LYS F 389 4529 4017 2950 -255 466 -565 C ATOM 5727 O LYS F 389 23.902 5.131 -35.891 1.00 31.37 O ANISOU 5727 O LYS F 389 4806 4031 3083 -274 611 -673 O ATOM 5728 N ASP F 390 24.204 3.466 -37.393 1.00 29.12 N ANISOU 5728 N ASP F 390 4269 4006 2789 -251 455 -550 N ATOM 5729 CA ASP F 390 23.576 2.440 -36.575 1.00 29.97 C ANISOU 5729 CA ASP F 390 4424 4105 2858 -296 612 -643 C ATOM 5730 CB ASP F 390 22.041 2.586 -36.553 1.00 30.71 C ANISOU 5730 CB ASP F 390 4366 4164 3137 -237 789 -763 C ATOM 5731 CG ASP F 390 21.410 2.597 -37.954 1.00 30.11 C ANISOU 5731 CG ASP F 390 4012 4192 3236 -122 680 -736 C ATOM 5732 OD1 ASP F 390 21.906 1.900 -38.876 1.00 31.34 O ANISOU 5732 OD1 ASP F 390 4099 4466 3341 -128 537 -651 O ATOM 5733 OD2 ASP F 390 20.396 3.303 -38.134 1.00 27.66 O ANISOU 5733 OD2 ASP F 390 3554 3847 3110 -10 729 -811 O ATOM 5734 C ASP F 390 23.993 1.035 -37.017 1.00 29.58 C ANISOU 5734 C ASP F 390 4340 4171 2729 -323 541 -594 C ATOM 5735 O ASP F 390 24.751 0.863 -37.972 1.00 28.60 O ANISOU 5735 O ASP F 390 4127 4153 2588 -291 379 -507 O ATOM 5736 N GLU F 391 23.482 0.046 -36.293 1.00 30.84 N ANISOU 5736 N GLU F 391 4594 4290 2833 -389 685 -659 N ATOM 5737 CA GLU F 391 23.729 -1.385 -36.518 1.00 30.78 C ANISOU 5737 CA GLU F 391 4622 4325 2747 -417 652 -631 C ATOM 5738 CB GLU F 391 22.983 -2.177 -35.421 1.00 31.99 C ANISOU 5738 CB GLU F 391 4962 4364 2827 -533 875 -709 C ATOM 5739 CG GLU F 391 23.324 -3.638 -35.334 1.00 31.45 C ANISOU 5739 CG GLU F 391 5056 4259 2634 -576 853 -670 C ATOM 5740 CD GLU F 391 22.692 -4.319 -34.139 1.00 33.38 C ANISOU 5740 CD GLU F 391 5573 4355 2756 -724 1088 -721 C ATOM 5741 OE1 GLU F 391 23.273 -5.342 -33.707 1.00 33.05 O ANISOU 5741 OE1 GLU F 391 5804 4219 2535 -744 1036 -654 O ATOM 5742 OE2 GLU F 391 21.639 -3.850 -33.633 1.00 30.81 O ANISOU 5742 OE2 GLU F 391 5202 3997 2506 -814 1329 -829 O ATOM 5743 C GLU F 391 23.286 -1.857 -37.909 1.00 30.79 C ANISOU 5743 C GLU F 391 4372 4443 2884 -367 585 -630 C ATOM 5744 O GLU F 391 24.001 -2.594 -38.588 1.00 30.38 O ANISOU 5744 O GLU F 391 4307 4463 2773 -336 456 -576 O ATOM 5745 N GLN F 392 22.099 -1.421 -38.324 1.00 32.45 N ANISOU 5745 N GLN F 392 4380 4677 3273 -346 666 -706 N ATOM 5746 CA GLN F 392 21.515 -1.817 -39.610 1.00 32.48 C ANISOU 5746 CA GLN F 392 4144 4800 3398 -304 583 -727 C ATOM 5747 CB GLN F 392 20.092 -1.260 -39.718 1.00 34.09 C ANISOU 5747 CB GLN F 392 4120 5020 3814 -271 678 -843 C ATOM 5748 CG GLN F 392 19.442 -1.344 -41.095 1.00 35.80 C ANISOU 5748 CG GLN F 392 4067 5374 4160 -195 528 -866 C ATOM 5749 CD GLN F 392 19.152 -2.771 -41.513 1.00 38.28 C ANISOU 5749 CD GLN F 392 4332 5752 4461 -309 544 -935 C ATOM 5750 OE1 GLN F 392 19.360 -3.713 -40.739 1.00 38.79 O ANISOU 5750 OE1 GLN F 392 4575 5730 4433 -443 686 -960 O ATOM 5751 NE2 GLN F 392 18.687 -2.945 -42.749 1.00 38.16 N ANISOU 5751 NE2 GLN F 392 4110 5869 4519 -260 384 -963 N ATOM 5752 C GLN F 392 22.369 -1.346 -40.784 1.00 31.31 C ANISOU 5752 C GLN F 392 3932 4753 3213 -208 364 -613 C ATOM 5753 O GLN F 392 22.674 -2.123 -41.683 1.00 30.61 O ANISOU 5753 O GLN F 392 3793 4758 3081 -202 268 -594 O ATOM 5754 N SER F 393 22.754 -0.071 -40.752 1.00 31.83 N ANISOU 5754 N SER F 393 4026 4785 3285 -152 308 -546 N ATOM 5755 CA SER F 393 23.555 0.584 -41.804 1.00 31.84 C ANISOU 5755 CA SER F 393 4001 4859 3240 -99 140 -428 C ATOM 5756 CB SER F 393 23.778 2.031 -41.404 1.00 32.41 C ANISOU 5756 CB SER F 393 4160 4818 3334 -79 137 -379 C ATOM 5757 OG SER F 393 22.513 2.621 -41.159 1.00 36.78 O ANISOU 5757 OG SER F 393 4636 5288 4050 2 210 -458 O ATOM 5758 C SER F 393 24.904 -0.068 -42.095 1.00 31.09 C ANISOU 5758 C SER F 393 3969 4851 2992 -139.

63. 365 C ATOM 5759 O SER F 393 25.370 -0.089 -43.238 1.00 31.67 O ANISOU 5759 O SER F 393 3975 5039 3019 -116 -36 -305 O ATOM 5760 N ILE F 394 25.531 -0.560 -41.031 1.00 30.78 N ANISOU 5760 N ILE F 394 4068 4760 2868 -190 110 -387 N ATOM 5761 CA ILE F 394 26.767 -1.307 -41.083 1.00 29.79 C ANISOU 5761 CA ILE F 394 3986 4710 2624 -191.

33. 359 C ATOM 5762 CB ILE F 394 27.351 -1.480 -39.645 1.00 29.65 C ANISOU 5762 CB ILE F 394 4156 4598 2511 -226.

48. 374 C ATOM 5763 CG1 ILE F 394 27.823 -0.134 -39.098 1.00 29.52 C ANISOU 5763 CG1 ILE F 394 4191 4541 2482 -279.

24. 348 C ATOM 5764 CD1 ILE F 394 27.916 -0.060 -37.553 1.00 31.10 C ANISOU 5764 CD1 ILE F 394 4613 4618 2587 -330.

64. 390 C ATOM 5765 CG2 ILE F 394 28.466 -2.533 -39.621 1.00 29.07 C ANISOU 5765 CG2 ILE F 394 4119 4590 2336 -174 -54 -367 C ATOM 5766 C ILE F 394 26.499 -2.669 -41.731 1.00 29.71 C ANISOU 5766 C ILE F 394 3929 4753 2607 -158.

31. 404 C ATOM 5767 O ILE F 394 27.278 -3.120 -42.577 1.00 29.55 O ANISOU 5767 O ILE F 394 3847 4847 2533 -116 -47 -388 O ATOM 5768 N ALA F 395 25.403 -3.316 -41.324 1.00 30.22 N ANISOU 5768 N ALA F 395 4027 4730 2726 -194 137 -478 N ATOM 5769 CA ALA F 395 25.009 -4.588 -41.908 1.00 30.57 C ANISOU 5769 CA ALA F 395 4048 4791 2775 -201 149 -541 C ATOM 5770 CB ALA F 395 23.837 -5.225 -41.145 1.00 31.36 C ANISOU 5770 CB ALA F 395 4215 4766 2934 -302 310 -630 C ATOM 5771 C ALA F 395 24.716 -4.452 -43.403 1.00 30.78 C ANISOU 5771 C ALA F 395 3889 4961 2846 -163.

60. 548 C ATOM 5772 O ALA F 395 25.104 -5.325 -44.164 1.00 31.52 O ANISOU 5772 O ALA F 395 3978 5117 2882 -138.

10. 576 O ATOM 5773 N GLU F 396 24.072 -3.354 -43.821 1.00 31.71 N ANISOU 5773 N GLU F 396 3881 5119 3047 -145.

31. 523 N ATOM 5774 CA GLU F 396 23.861 -3.029 -45.257 1.00 31.94 C ANISOU 5774 CA GLU F 396 3780 5281 3073 -95 -93 -498 C ATOM 5775 CB GLU F 396 23.037 -1.743 -45.443 1.00 33.01 C ANISOU 5775 CB GLU F 396 3825 5402 3315 -41 -139 -461 C ATOM 5776 CG GLU F 396 21.538 -1.987 -45.467 1.00 35.48 C ANISOU 5776 CG GLU F 396 3973 5718 3789 -123 -581 C ATOM 5777 CD GLU F 396 20.680 -0.802 -44.997 1.00 38.57 C ANISOU 5777 CD GLU F 396 4281 6037 433.

44. 103 -589 C ATOM 5778 OE1 GLU F 396 21.223 0.325 -44.807 1.00 39.47 O ANISOU 5778 OE1 GLU F 396 4500 6075 442.

99. 126 -482 O ATOM 5779 OE2 GLU F 396 19.447 -1.008 -44.817 1.00 35.64 O ANISOU 5779 OE2 GLU F 396 3729 5680 413.

47. 55 -721 O ATOM 5780 C GLU F 396 25.163 -2.938 -46.052 1.00 31.50 C ANISOU 5780 C GLU F 396 3762 5332 2874 -69 -168 -417 C ATOM 5781 O GLU F 396 25.290 -3.588 -47.089 1.00 32.61 O ANISOU 5781 O GLU F 396 3871 5579 2942 -56 -221 -449 O ATOM 5782 N ALA F 397 26.128 -2.156 -45.567 1.00 30.36 N ANISOU 5782 N ALA F 397 3680 5169 2688 -79 -159 -334 N ATOM 5783 CA ALA F 397 27.425 -2.017 -46.242 1.00 30.05 C ANISOU 5783 CA ALA F 397 3636 5250 2530 -86 -193 -277 C ATOM 5784 CB ALA F 397 28.335 -0.987 -45.512 1.00 29.70 C ANISOU 5784 CB ALA F 397 3637 5170 2479 -140 -180 -206 C ATOM 5785 C ALA F 397 28.164 -3.342 -46.421 1.00 29.77 C ANISOU 5785 C ALA F 397 3596 5288 2428 -49 -182 -356 C ATOM 5786 O ALA F 397 28.768 -3.583 -47.484 1.00 30.19 O ANISOU 5786 O ALA F 397 3600 5481 2390 -195 -364 O ATOM 5787 N ILE F 398 28.116 -4.184 -45.387 1.00 29.18 N ANISOU 5787 N ILE F 398 3597 5103 2385 -28 -151 -416 N ATOM 5788 CA ILE F 398 28.785 -5.500 -45.391 1.00 29.82 C ANISOU 5788 CA ILE F 398 3721 5193 2418.

45. 156 -491 C ATOM 5789 CB ILE F 398 28.763 -6.184 -43.978 1.00 30.01 C ANISOU 5789 CB ILE F 398 3908 5042 245.

64. 137 -511 C ATOM 5790 CG1 ILE F 398 29.506 -5.325 -42.937 1.00 28.78 C ANISOU 5790 CG1 ILE F 398 3784 4871 227.

53. 173 -446 C ATOM 5791 CD1 ILE F 398 29.361 -5.799 -41.514 1.00 29.65 C ANISOU 5791 CD1 ILE F 398 4105 4806 235.

54. 162 -447 C ATOM 5792 CG2 ILE F 398 29.370 -7.571 -44.042 1.00 30.84 C ANISOU 5792 CG2 ILE F 398 4096 5109 2512 173 -164 -580 C ATOM 5793 C ILE F 398 28.199 -6.428 -46.466 1.00 30.35 C ANISOU 5793 C ILE F 398 3770 5297 246.

59. 152 -577 C ATOM 5794 O ILE F 398 28.943 -7.040 -47.237 1.00 31.40 O ANISOU 5794 O ILE F 398 3877 5526 2528 124 -162 -630 O ATOM 5795 N ILE F 399 26.868 -6.485 -46.522 1.00 30.23 N ANISOU 5795 N ILE F 399 3752 5216 2518 -8 -136 -610 N ATOM 5796 CA ILE F 399 26.139 -7.273 -47.508 1.00 30.68 C ANISOU 5796 CA ILE F 399 3781 5309 2565 -31 -156 -710 C ATOM 5797 CB ILE F 399 24.585 -7.231 -47.249 1.00 31.14 C ANISOU 5797 CB ILE F 399 3785 5298 2749 -126 -136 -763 C ATOM 5798 CG1 ILE F 399 24.226 -7.902 -45.914 1.00 29.45 C ANISOU 5798 CG1 ILE F 399 3695 4892 2602 -193 -16 -803 C ATOM 5799 CD1 ILE F 399 22.950 -7.376 -45.272 1.00 29.44 C ANISOU 5799 CD1 ILE F 399 3606 4839 2739 -287.

62. 831 C ATOM 5800 CG2 ILE F 399 23.800 -7.896 -48.410 1.00 32.52 C ANISOU 5800 CG2 ILE F 399 3891 5551 2914 -170 -202 -881 C ATOM 5801 C ILE F 399 26.479 -6.784 -48.919 1.00 31.25 C ANISOU 5801 C ILE F 399 3772 5569 2531 -6 -226 -685 C ATOM 5802 O ILE F 399 26.773 -7.594 -49.799 1.00 32.29 O ANISOU 5802 O ILE F 399 3926 5770 257.

20. 235 -772 O ATOM 5803 N VAL F 400 26.442 -5.468 -49.127 1.00 31.26 N ANISOU 5803 N VAL F 400 3717 5633 2527 -17 -266 -569 N ATOM 5804 CA VAL F 400 26.703 -4.862 -50.439 1.00 31.99 C ANISOU 5804 CA VAL F 400 3791 5879 2484 -16 -326 -512 C ATOM 5805 CB VAL F 400 26.552 -3.321 -50.424 1.00 32.28 C ANISOU 5805 CB VAL F 400 3826 5904 2535 -32 -369 -359 C ATOM 5806 CG1 VAL F 400 27.154 -2.712 -51.702 1.00 31.55 C ANISOU 5806 CG1 VAL F 400 3785 5949 2253 -57 -395 -270 C ATOM 5807 CG2 VAL F 400 25.081 -2.906 -50.237 1.00 31.82 C ANISOU 5807 CG2 VAL F 400 3714 5767 2609 -9 -454 -364 C ATOM 5808 C VAL F 400 28.110 -5.188 -50.913 1.00 32.53 C ANISOU 5808 C VAL F 400 3873 6063 242.

4. 258 -527 C ATOM 5809 O VAL F 400 28.320 -5.462 -52.094 1.00 33.48 O ANISOU 5809 O VAL F 400 4010 6312 239.

3. 262 -566 O ATOM 5810 N ALA F 401 29.054 -5.149 -49.973 1.00 31.73 N ANISOU 5810 N ALA F 401 3756 5926 237.

25. 198 -510 N ATOM 5811 CA ALA F 401 30.462 -5.417 -50.239 1.00 32.29 C ANISOU 5811 CA ALA F 401 3773 6123 237.

61. 131 -547 C ATOM 5812 CB ALA F 401 31.316 -4.940 -49.082 1.00 31.23 C ANISOU 5812 CB ALA F 401 3591 5955 232.

61. 122 -500 C ATOM 5813 C ALA F 401 30.738 -6.885 -50.529 1.00 32.85 C ANISOU 5813 C ALA F 401 3863 6199 2419 165 -106 -703 C ATOM 5814 O ALA F 401 31.652 -7.205 -51.280 1.00 34.52 O ANISOU 5814 O ALA F 401 4018 6556 2542 209 -41 -775 O ATOM 5815 N MSE F 402 29.963 -7.768 -49.913 1.00 32.87 N ANISOU 5815 N MSE F 402 3957 6031 2501 198 -138 -765 N ATOM 5816 CA MSE F 402 30.121 -9.221 -50.081 1.00 34.29 C ANISOU 5816 CA MSE F 402 4216 6142 2669 295 -120 -914 C ATOM 5817 CB MSE F 402 29.405 -10.001 -48.955 1.00 33.61 C ANISOU 5817 CB MSE F 402 4274 5812 2686 294 -135 -936 C ATOM 5818 CG MSE F 402 30.159 -10.004 -47.602 1.00 34.31 C ANISOU 5818 CG MSE F 402 4411 5796 2829 379 -152 -874 C ATOM 5819 SE MSE F 402 29.225 -10.945 -46.127 0.90 35.69 SE ANISOU 5819 SE MSE F 402 4858 5634 3068 337 -136 -872 SE ATOM 5820 CE MSE F 402 30.613 -10.934 -44.782 1.00 35.68 C ANISOU 5820 CE MSE F 402 4931 5574 3050 510 -223 -797 C ATOM 5821 C MSE F 402 29.589 -9.629 -51.439 1.00 34.50 C ANISOU 5821 C MSE F 402 4268 6255 2587 255 -119 -1011 C ATOM 5822 O MSE F 402 30.190 -10.441 -52.110 1.00 36.42 O ANISOU 5822 O MSE F 402 4535 6549 2753 337 -73 -1137 O ATOM 5823 N VAL F 403 28.465 -9.043 -51.840 1.00 34.25 N ANISOU 5823 N VAL F 403 4226 6243 2545 142 -183 -962 N ATOM 5824 CA VAL F 403 27.919 -9.227 -53.188 1.00 34.82 C ANISOU 5824 CA VAL F 403 4323 6427 248.

94. 232 -1038 C ATOM 5825 CB VAL F 403 26.495 -8.620 -53.318 1.00 34.53 C ANISOU 5825 CB VAL F 403 4248 6380 2494 0 -356 -989 C ATOM 5826 CG1 VAL F 403 25.966 -8.754 -54.767 1.00 35.80 C ANISOU 5826 CG1 VAL F 403 4442 6680 2479 -40 -460 -1064 C ATOM 5827 CG2 VAL F 403 25.531 -9.291 -52.314 1.00 33.68 C ANISOU 5827 CG2 VAL F 403 4139 6086 2573 -50 -354 -1061 C ATOM 5828 C VAL F 403 28.878 -8.653 -54.249 1.00 35.95 C ANISOU 5828 C VAL F 403 4446 6779 2433 106 -179 -1003 C ATOM 5829 O VAL F 403 29.190 -9.332 -55.244 1.00 37.21 O ANISOU 5829 O VAL F 403 4664 7031 2443 127 -138 -1133 O ATOM 5830 N PHE F 404 29.347 -7.420 -54.010 1.00 34.96 N ANISOU 5830 N PHE F 404 4259 6715 230.

72. 159 -839 N ATOM 5831 CA PHE F 404 30.282 -6.688 -54.895 1.00 36.53 C ANISOU 5831 CA PHE F 404 4449 7101 233.

28. 72 -777 C ATOM 5832 CB PHE F 404 30.606 -5.293 -54.309 1.00 35.90 C ANISOU 5832 CB PHE F 404 4324 7008 2310 -45 -63 -589 C ATOM 5833 CG PHE F 404 31.373 -4.375 -55.245 1.00 37.51 C ANISOU 5833 CG PHE F 404 4558 7371 2322 -153.

35. 495 C ATOM 5834 CD1 PHE F 404 30.713 -3.660 -56.254 1.00 38.35 C ANISOU 5834 CD1 PHE F 404 4819 7508 2243 -225 -40 -382 C ATOM 5835 CE1 PHE F 404 31.414 -2.801 -57.112 1.00 37.22 C ANISOU 5835 CE1 PHE F 404 4768 7483 1890 -354.

72. 274 C ATOM 5836 CZ PHE F 404 32.771 -2.645 -56.966 1.00 39.43 C ANISOU 5836 CZ PHE F 404 4931 7877 2174 -433 279 -303 C ATOM 5837 CE2 PHE F 404 33.452 -3.342 -55.961 1.00 39.28 C ANISOU 5837 CE2 PHE F 404 4699 7858 2368 -343 332 -436 C ATOM 5838 CD2 PHE F 404 32.747 -4.197 -55.097 1.00 38.17 C ANISOU 5838 CD2 PHE F 404 4522 7571 2408 -192 198 -517 C ATOM 5839 C PHE F 404 31.571 -7.463 -55.140 1.00 37.46 C ANISOU 5839 C PHE F 404 4505 7327 2403 10.

81. 918 C ATOM 5840 O PHE F 404 32.134 -7.391 -56.225 1.00 39.22 O ANISOU 5840 O PHE F 404 4747 7721 2433 66 186 -960 O ATOM 5841 N SER F 405 32.025 -8.203 -54.131 1.00 37.05 N ANISOU 5841 N SER F 405 4389 7171 2517 22.

94. 995 N ATOM 5842 CA SER F 405 33.281 -8.958 -54.222 1.00 39.28 C ANISOU 5842 CA SER F 405 4576 7544 2804 352 212 -1143 C ATOM 5843 CB SER F 405 33.727 -9.455 -52.845 1.00 38.82 C ANISOU 5843 CB SER F 405 4463 7343 2945 492 158 -1160 C ATOM 5844 OG SER F 405 33.038 -10.651 -52.515 1.00 40.42 O ANISOU 5844 OG SER F 405 4824 7332 3201 58.

93. 1254 O ATOM 5845 C SER F 405 33.166 -10.136 -55.180 1.00 40.69 C ANISOU 5845 C SER F 405 4856 7736 2869 429 260 -1340 C ATOM 5846 O SER F 405 34.178 -10.658 -55.653 1.00 42.13 O ANISOU 5846 O SER F 405 4962 8038 3005 534 391 -1487 O ATOM 5847 N GLN F 406 31.920 -10.534 -55.450 1.00 40.68 N ANISOU 5847 N GLN F 406 5011 7615 2832 371 155 -1361 N ATOM 5848 CA GLN F 406 31.572 -11.630 -56.381 1.00 42.61 C ANISOU 5848 CA GLN F 406 5392 7843 2954 399 169 -1558 C ATOM 5849 CB GLN F 406 31.955 -11.281 -57.824 1.00 44.04 C ANISOU 5849 CB GLN F 406 5602 8265 2868 332 270 -1606 C ATOM 5850 CG GLN F 406 31.191 -10.103 -58.371 1.00 43.15 C ANISOU 5850 CG GLN F 406 5540 8242 2614 163 170 -1425 C ATOM 5851 CD GLN F 406 31.738 -9.591 -59.677 1.00 44.42 C ANISOU 5851 CD GLN F 406 5768 8633 2476 81 291 -1422 C ATOM 5852 OE1 GLN F 406 32.951 -9.500 -59.865 1.00 43.92 O ANISOU 5852 OE1 GLN F 406 5611 8710 2369 105 499 -1468 O ATOM 5853 NE2 GLN F 406 30.838 -9.241 -60.593 1.00 45.45 N ANISOU 5853 NE2 GLN F 406 6064 8814 2393 -23 159 -1372 N ATOM 5854 C GLN F 406 32.173 -12.968 -55.971 1.00 43.95 C ANISOU 5854 C GLN F 406 5600 7871 3227 589 226 -1742 C ATOM 5855 O GLN F 406 32.433 -13.808 -56.819 1.00 46.15 O ANISOU 5855 O GLN F 406 5963 8178 3395 657 304 -1937 O ATOM 5856 N GLU F 407 32.373 -13.145 -54.666 1.00 43.66 N ANISOU 5856 N GLU F 407 5534 7667 3389 684 177 -1678 N ATOM 5857 CA GLU F 407 32.972 -14.356 -54.087 1.00 45.89 C ANISOU 5857 CA GLU F 407 5886 7768 3781 902 190 -1811 C ATOM 5858 CB GLU F 407 33.245 -14.162 -52.597 1.00 44.16 C ANISOU 5858 CB GLU F 407 5633 7413 3733 980 106 -1674 C ATOM 5859 CG GLU F 407 34.489 -13.382 -52.270 1.00 44.97 C ANISOU 5859 CG GLU F 407 5487 7716 3881 1066 133 -1614 C ATOM 5860 CD GLU F 407 35.177 -13.876 -51.008 1.00 45.76 C ANISOU 5860 CD GLU F 407 5591 7667 4127 127.

35. 1602 C ATOM 5861 OE1 GLU F 407 34.788 -14.945 -50.485 1.00 46.21 O ANISOU 5861 OE1 GLU F 407 5887 7443 4229 1387 -30 -1645 O ATOM 5862 OE2 GLU F 407 36.126 -13.199 -50.553 1.00 46.06 O ANISOU 5862 OE2 GLU F 407 5409 7866 4226 133.

14. 1552 O ATOM 5863 C GLU F 407 32.093 -15.581 -54.248 1.00 47.47 C ANISOU 5863 C GLU F 407 6337 7722 3977 890 155 -1951 C ATOM 5864 O GLU F 407 30.874 -15.486 -54.144 1.00 46.49 O ANISOU 5864 O GLU F 407 6303 7502 3860 70.

80. 1898 O ATOM 5865 N ASP F 408 32.713 -16.737 -54.463 1.00 51.07 N ANISOU 5865 N ASP F 408 6898 8065 4441 1090 210 -2142 N ATOM 5866 CA ASP F 408 31.942 -17.949 -54.697 1.00 53.71 C ANISOU 5866 CA ASP F 408 7506 8138 4762 1059 193 -2300 C ATOM 5867 CB ASP F 408 32.753 -19.039 -55.396 1.00 56.74 C ANISOU 5867 CB ASP F 408 7989 8471 5099 1286 290 -2553 C ATOM 5868 CG ASP F 408 31.879 -19.947 -56.264 1.00 60.34 C ANISOU 5868 CG ASP F 408 8697 8784 5445 1155 300 -2755 C ATOM 5869 OD1 ASP F 408 31.500 -19.542 -57.393 1.00 61.41 O ANISOU 5869 OD1 ASP F 408 8794 9144 5396 993 324 -2821 O ATOM 5870 OD2 ASP F 408 31.573 -21.074 -55.817 1.00 63.81 O ANISOU 5870 OD2 ASP F 408 9399 8875 5969 1205 273 -2849 O ATOM 5871 C ASP F 408 31.241 -18.477 -53.441 1.00 53.40 C ANISOU 5871 C ASP F 408 7660 7761 4869 1016 107 -2210 C ATOM 5872 O ASP F 408 30.214 -19.139 -53.548 1.00 54.39 O ANISOU 5872 O ASP F 408 7984 7691 4992 85.

89. 2287 O ATOM 5873 N ACYS F 409 31.777 -18.185 -52.260 0.50 52.75 N ANISOU 5873 N ACYS F 409 7531 7613 4899 113.

60. 2057 N ATOM 5874 N BCYS F 409 31.777 -18.185 -52.260 0.50 52.75 N ANISOU 5874 N BCYS F 409 7531 7613 4899 113.

60. 2057 N ATOM 5875 CA ACYS F 409 31.089 -18.592 -51.034 0.50 52.65 C ANISOU 5875 CA ACYS F 409 7738 7288 4981 106.

2. 1951 C ATOM 5876 CA BCYS F 409 31.089 -18.592 -51.034 0.50 52.65 C ANISOU 5876 CA BCYS F 409 7738 7288 4981 106.

2. 1951 C ATOM 5877 CB ACYS F 409 32.047 -18.636 -49.835 0.50 52.96 C ANISOU 5877 CB ACYS F 409 7800 7221 5099 1305 -69 -1839 C ATOM 5878 CB BCYS F 409 32.047 -18.636 -49.835 0.50 52.96 C ANISOU 5878 CB BCYS F 409 7800 7221 5099 1305 -69 -1839 C ATOM 5879 SG ACYS F 409 32.091 -17.163 -48.811 0.50 52.55 S ANISOU 5879 SG ACYS F 409 7540 7342 5085 1205 -130 -1593 S ATOM 5880 SG BCYS F 409 32.091 -17.163 -48.811 0.50 52.55 S ANISOU 5880 SG BCYS F 409 7540 7342 5085 1205 -130 -1593 S ATOM 5881 C ACYS F 409 29.827 -17.739 -50.774 0.50 50.12 C ANISOU 5881 C ACYS F 409 7348 7022 4672 755 -13 -1821 C ATOM 5882 C BCYS F 409 29.827 -17.739 -50.774 0.50 50.12 C ANISOU 5882 C BCYS F 409 7348 7022 4672 755 -13 -1821 C ATOM 5883 O ACYS F 409 28.886 -18.205 -50.136 0.50 50.44 O ANISOU 5883 O ACYS F 409 7577 6823 4766 597 -7 -1802 O ATOM 5884 O BCYS F 409 28.886 -18.205 -50.136 0.50 50.44 O ANISOU 5884 O BCYS F 409 7577 6823 4766 597 -7 -1802 O ATOM 5885 N MSE F 410 29.811 -16.507 -51.289 1.00 48.14 N ANISOU 5885 N MSE F 410 6837 7079 4377 671 -19 -1743 N ATOM 5886 CA MSE F 410 28.586 -15.667 -51.329 1.00 46.32 C ANISOU 5886 CA MSE F 410 6511 6930 4158 419 -48 -1656 C ATOM 5887 CB MSE F 410 28.941 -14.221 -51.724 1.00 44.79 C ANISOU 5887 CB MSE F 410 6071 7035 3913 406 -68 -1529 C ATOM 5888 CG MSE F 410 27.762 -13.229 -51.931 1.00 42.99 C ANISOU 5888 CG MSE F 410 5730 6910 3694 209 -126 -1442 C ATOM 5889 SE MSE F 410 26.955 -13.098 -53.730 0.90 42.31 SE ANISOU 5889 SE MSE F 410 5600 7035 343.

86. 204 -1557 SE ATOM 5890 CE MSE F 410 28.542 -12.628 -54.751 1.00 41.76 C ANISOU 5890 CE MSE F 410 5476 7222 3170 230 -121 -1549 C ATOM 5891 C MSE F 410 27.565 -16.259 -52.323 1.00 47.69 C ANISOU 5891 C MSE F 410 6753 7090 4276 253 -60 -1820 C ATOM 5892 O MSE F 410 26.393 -16.467 -51.992 1.00 47.49 O ANISOU 5892 O MSE F 410 6775 6944 432.

57.

75. 1837 O ATOM 5893 N ILE F 411 28.020 -16.533 -53.544 1.00 48.99 N ANISOU 5893 N ILE F 411 6915 7393 4304 318 -48 -1959 N ATOM 5894 CA ILE F 411 27.176 -17.189 -54.556 1.00 50.31 C ANISOU 5894 CA ILE F 411 7177 7552 4386 171 -80 -2148 C ATOM 5895 CB ILE F 411 27.852 -17.190 -55.945 1.00 51.34 C ANISOU 5895 CB ILE F 411 7295 7903 4310 257 -53 -2275 C ATOM 5896 CG1 ILE F 411 27.605 -15.837 -56.612 1.00 50.21 C ANISOU 5896 CG1 ILE F 411 6965 8064 4047 166 -123 -2142 C ATOM 5897 CD1 ILE F 411 28.722 -15.359 -57.495 1.00 52.42 C ANISOU 5897 CD1 ILE F 411 7190 8586 4140 279 -32 -2145 C ATOM 5898 CG2 ILE F 411 27.314 -18.312 -56.826 1.00 53.79 C ANISOU 5898 CG2 ILE F 411 7799 8112 4525 167 -66 -2531 C ATOM 5899 C ILE F 411 26.671 -18.575 -54.108 1.00 51.93 C ANISOU 5899 C ILE F 411 7639 7413 4677 105 -50 -2292 C ATOM 5900 O ILE F 411 25.517 -18.904 -54.355 1.00 53.42 O ANISOU 5900 O ILE F 411 7863 7547 4889 -126 -93 -2390 O ATOM 5901 N LYS F 412 27.502 -19.356 -53.416 1.00 52.22 N ANISOU 5901 N LYS F 412 7857 7215 4771 29.

14. 2301 N ATOM 5902 CA LYS F 412 27.074 -20.655 -52.866 1.00 53.75 C ANISOU 5902 CA LYS F 412 8365 7019 5038 23.

51. 2401 C ATOM 5903 CB LYS F 412 28.288 -21.518 -52.480 1.00 55.14 C ANISOU 5903 CB LYS F 412 8752 6970 5227 55.

88. 2438 C ATOM 5904 CG LYS F 412 29.038 -22.152 -53.648 1.00 57.75 C ANISOU 5904 CG LYS F 412 9134 7352 5454 744 126 -2667 C ATOM 5905 CD LYS F 412 28.231 -23.272 -54.325 1.00 61.07 C ANISOU 5905 CD LYS F 412 9825 7547 5831 564 149 -2906 C ATOM 5906 CE LYS F 412 28.940 -23.834 -55.572 1.00 63.36 C ANISOU 5906 CE LYS F 412 10174 7912 5988 740 204 -3162 C ATOM 5907 NZ LYS F 412 28.944 -22.908 -56.735 1.00 61.64 N ANISOU 5907 NZ LYS F 412 9691 8127 5602 663 198 -3197 N ATOM 5908 C LYS F 412 26.100 -20.546 -51.670 1.00 52.80 C ANISOU 5908 C LYS F 412 8297 6719 5046 1.

66. 2268 C ATOM 5909 O LYS F 412 25.481 -21.540 -51.279 1.00 54.85 O ANISOU 5909 O LYS F 412 8819 6665 5356 -135 119 -2349 O ATOM 5910 N ALA F 413 25.965 -19.345 -51.104 1.00 50.11 N ANISOU 5910 N ALA F 413 7723 6567 4749 -13.

43. 2077 N ATOM 5911 CA ALA F 413 25.099 -19.097 -49.933 1.00 48.96 C ANISOU 5911 CA ALA F 413 7598 6290 4712 -206.

90. 1956 C ATOM 5912 CB ALA F 413 25.724 -18.033 -49.014 1.00 46.53 C ANISOU 5912 CB ALA F 413 7166 6089 4424 -67.

75. 1735 C ATOM 5913 C ALA F 413 23.642 -18.733 -50.269 1.00 48.81 C ANISOU 5913 C ALA F 413 7393 6390 4762 -515.

84. 2024 C ATOM 5914 O ALA F 413 22.815 -18.557 -49.364 1.00 48.53 O ANISOU 5914 O ALA F 413 7342 6265 4831 -700 159 -1964 O ATOM 5915 N VAL F 414 23.341 -18.612 -51.562 1.00 49.08 N ANISOU 5915 N VAL F 414 7279 6637 4730 -561 -7 -2158 N ATOM 5916 CA VAL F 414 21.970 -18.436 -52.037 1.00 49.54 C ANISOU 5916 CA VAL F 414 7153 6817 4854 -830 -65 -2269 C ATOM 5917 CB VAL F 414 21.929 -18.102 -53.563 1.00 50.27 C ANISOU 5917 CB VAL F 414 7101 7196 4804 -801 -222 -2378 C ATOM 5918 CG1 VAL F 414 20.491 -17.927 -54.072 1.00 49.09 C ANISOU 5918 CG1 VAL F 414 6737 7190 4726 -1054 -341 -2505 C ATOM 5919 CG2 VAL F 414 22.757 -16.861 -53.860 1.00 47.46 C ANISOU 5919 CG2 VAL F 414 6588 7096 4350 -582 -280 -2198 C ATOM 5920 C VAL F 414 21.156 -19.706 -51.750 1.00 52.59 C ANISOU 5920 C VAL F 414 7748 6913 5322 -1091.

27. 2442 C ATOM 5921 O VAL F 414 21.612 -20.824 -52.012 1.00 54.19 O ANISOU 5921 O VAL F 414 8243 6888 5458 -1056.

66. 2564 O ATOM 5922 N ARG F 415 19.960 -19.513 -51.195 1.00 53.57 N ANISOU 5922 N ARG F 415 7719 7037 5597 -1355.

78. 2459 N ATOM 5923 CA ARG F 415 19.009 -20.599 -50.933 1.00 56.86 C ANISOU 5923 CA ARG F 415 8279 7213 6113 -1686 189 -2636 C ATOM 5924 CB ARG F 415 18.679 -20.667 -49.434 1.00 56.75 C ANISOU 5924 CB ARG F 415 8382 6972 6208 -1824 400 -2512 C ATOM 5925 CG ARG F 415 19.868 -20.954 -48.513 1.00 56.55 C ANISOU 5925 CG ARG F 415 8721 6681 6086 -1584 482 -2321 C ATOM 5926 CD ARG F 415 20.259 -22.434 -48.501 1.00 61.81 C ANISOU 5926 CD ARG F 415 9852 6947 6685 -1607 548 -2415 C ATOM 5927 NE ARG F 415 21.475 -22.674 -47.715 1.00 62.49 N ANISOU 5927 NE ARG F 415 10262 6805 6676 -1304 561 -2235 N ATOM 5928 CZ ARG F 415 22.689 -22.855 -48.237 1.00 62.58 C ANISOU 5928 CZ ARG F 415 10363 6824 6592 -954 445 -2229 C ATOM 5929 NH1 ARG F 415 22.868 -22.842 -49.557 1.00 61.25 N ANISOU 5929 NH1 ARG F 415 10028 6864 6379 -878 340 -2390 N ATOM 5930 NH2 ARG F 415 23.727 -23.063 -47.431 1.00 62.31 N ANISOU 5930 NH2 ARG F 415 10583 6594 6498 -677 434 -2075 N ATOM 5931 C ARG F 415 17.730 -20.345 -51.734 1.00 58.42 C ANISOU 5931 C ARG F 415 8134 7663 6402 -1935.

70. 2824 C ATOM 5932 O ARG F 415 17.145 -19.259 -51.654 1.00 58.20 O ANISOU 5932 O ARG F 415 7749 7898 6468 -1933.

2. 2757 O ATOM 5933 N GLY F 416 17.295 -21.329 -52.509 1.00 61.08 N ANISOU 5933 N GLY F 416 8575 7920 6715 -2136.

26. 3069 N ATOM 5934 CA GLY F 416 16.104 -21.163 -53.341 1.00 62.81 C ANISOU 5934 CA GLY F 416 8459 8396 7010 -2372 -136 -3277 C ATOM 5935 C GLY F 416 16.429 -20.481 -54.658 1.00 61.99 C ANISOU 5935 C GLY F 416 8200 8622 6732 -2155 -406 -3291 C ATOM 5936 O GLY F 416 17.592 -20.198 -54.941 1.00 59.93 O ANISOU 5936 O GLY F 416 8093 8382 6296 -1854 -424 -3155 O ATOM 5937 N ASP F 417 15.403 -20.224 -55.467 1.00 63.90 N ANISOU 5937 N ASP F 417 8138 9127 7013 -2314 -618 -3460 N ATOM 5938 CA ASP F 417 15.591 -19.601 -56.780 1.00 64.06 C ANISOU 5938 CA ASP F 417 8056 9458 6828 -2137 -900 -3476 C ATOM 5939 CB ASP F 417 14.602 -20.172 -57.801 1.00 67.95 C ANISOU 5939 CB ASP F 417 8438 10082 7298 -2398 -1118 -3786 C ATOM 5940 CG ASP F 417 15.090 -21.481 -58.420 1.00 70.01 C ANISOU 5940 CG ASP F 417 9098 10118 7385 -2495 -1067 -4000 C ATOM 5941 OD1 ASP F 417 16.312 -21.756 -58.345 1.00 67.20 O ANISOU 5941 OD1 ASP F 417 9070 9582 6879 -2269 -919 -3895 O ATOM 5942 OD2 ASP F 417 14.257 -22.228 -58.994 1.00 73.52 O ANISOU 5942 OD2 ASP F 417 9518 10568 7849 -2792 -1180 -4292 O ATOM 5943 C ASP F 417 15.497 -18.081 -56.723 1.00 62.18 C ANISOU 5943 C ASP F 417 7507 9500 6617 -1920 -1034 -3253 C ATOM 5944 O ASP F 417 14.874 -17.529 -55.816 1.00 61.19 O ANISOU 5944 O ASP F 417 7135 9393 6721 -1970 -960 -3173 O ATOM 5945 N LEU F 418 16.133 -17.413 -57.685 1.00 61.75 N ANISOU 5945 N LEU F 418 7496 9647 6320 -1686 -1210 -3156 N ATOM 5946 CA LEU F 418 16.118 -15.948 -57.745 1.00 60.49 C ANISOU 5946 CA LEU F 418 7114 9719 6152 -1472 -1351 -2931 C ATOM 5947 CB LEU F 418 17.537 -15.398 -57.923 1.00 57.76 C ANISOU 5947 CB LEU F 418 6989 9374 5583 -1201 -1274 -2707 C ATOM 5948 CG LEU F 418 18.593 -15.816 -56.888 1.00 55.19 C ANISOU 5948 CG LEU F 418 6875 8788 5307 -1122 -976 -2599 C ATOM 5949 CD1 LEU F 418 19.955 -15.240 -57.229 1.00 53.26 C ANISOU 5949 CD1 LEU F 418 6775 8610 4852 -874 -930 -2422 C ATOM 5950 CD2 LEU F 418 18.177 -15.419 -55.497 1.00 52.84 C ANISOU 5950 CD2 LEU F 418 6426 8377 5273 -1162 -838 -2481 C ATOM 5951 C LEU F 418 15.138 -15.398 -58.802 1.00 63.79 C ANISOU 5951 C LEU F 418 7283 10437 6516 -1492 -1711 -3027 C ATOM 5952 O LEU F 418 15.392 -15.465 -60.017 1.00 65.29 O ANISOU 5952 O LEU F 418 7619 10766 6424 -1442 -1904 -3087 O ATOM 5953 N ASN F 419 14.019 -14.860 -58.308 1.00 65.15 N ANISOU 5953 N ASN F 419 7085 10711 6958 -1553 -1798 -3047 N ATOM 5954 CA ASN F 419 12.905 -14.410 -59.137 1.00 69.14 C ANISOU 5954 CA ASN F 419 7285 11496 7490 -1571 -2166 -3170 C ATOM 5955 CB ASN F 419 11.688 -15.328 -58.915 1.00 72.59 C ANISOU 5955 CB ASN F 419 7461 11934 8184 -1910 -2173 -3488 C ATOM 5956 CG ASN F 419 11.896 -16.734 -59.469 1.00 75.06 C ANISOU 5956 CG ASN F 419 8060 12114 8344 -2158 -2126 -3731 C ATOM 5957 OD1 ASN F 419 12.169 -16.915 -60.657 1.00 76.13 O ANISOU 5957 OD1 ASN F 419 8378 12363 8185 -2114 -2350 -3807 O ATOM 5958 ND2 ASN F 419 11.741 -17.738 -58.608 1.00 76.18 N ANISOU 5958 ND2 ASN F 419 8272 11998 8674 -2427 -1828 -3861 N ATOM 5959 C ASN F 419 12.492 -12.941 -58.929 1.00 68.82 C ANISOU 5959 C ASN F 419 6962 11617 7568 -1329 -2328 -2971 C ATOM 5960 O ASN F 419 11.329 -12.583 -59.159 1.00 71.70 O ANISOU 5960 O ASN F 419 6960 12179 8104 -1346 -2585 -3092 O ATOM 5961 N PHE F 420 13.438 -12.093 -58.525 1.00 65.87 N ANISOU 5961 N PHE F 420 6754 11162 7112 -1099 -2193 -2683 N ATOM 5962 CA PHE F 420 13.118 -10.705 -58.172 1.00 65.85 C ANISOU 5962 CA PHE F 420 6538 11242 7241 -872 -2295 -2489 C ATOM 5963 CB PHE F 420 14.226 -10.056 -57.331 1.00 61.88 C ANISOU 5963 CB PHE F 420 6236 10564 6710 -720 -2025 -2217 C ATOM 5964 CG PHE F 420 14.370 -10.644 -55.947 1.00 60.67 C ANISOU 5964 CG PHE F 420 6083 10193 6774 -865 -1658 -2251 C ATOM 5965 CD1 PHE F 420 15.369 -11.592 -55.674 1.00 58.71 C ANISOU 5965 CD1 PHE F 420 6148 9758 6401 -954 -1418 -2253 C ATOM 5966 CE1 PHE F 420 15.511 -12.143 -54.394 1.00 56.02 C ANISOU 5966 CE1 PHE F 420 5866 9196 6224 -1073 -1110 -2262 C ATOM 5967 CZ PHE F 420 14.657 -11.740 -53.367 1.00 56.93 C ANISOU 5967 CZ PHE F 420 5728 9288 6616 -1135 -998 -2278 C ATOM 5968 CE2 PHE F 420 13.656 -10.794 -53.617 1.00 59.27 C ANISOU 5968 CE2 PHE F 420 5671 9783 7065 -1048 -1201 -2302 C ATOM 5969 CD2 PHE F 420 13.516 -10.248 -54.907 1.00 61.33 C ANISOU 5969 CD2 PHE F 420 5874 10254 7176 -897 -1551 -2282 C ATOM 5970 C PHE F 420 12.752 -9.824 -59.370 1.00 68.72 C ANISOU 5970 C PHE F 420 6852 11834 7423 -675 -2718 -2421 C ATOM 5971 O PHE F 420 13.329 -9.934 -60.459 1.00 69.39 O ANISOU 5971 O PHE F 420 7220 11989 7156 -637 -2864 -2384 O ATOM 5972 N VAL F 421 11.776 -8.954 -59.131 1.00 70.81 N ANISOU 5972 N VAL F 421 6770 12208 7928 -541 -2906 -2410 N ATOM 5973 CA VAL F 421 11.229 -8.033 -60.118 1.00 74.14 C ANISOU 5973 CA VAL F 421 7105 12827 8236 -313 -3351 -2341 C ATOM 5974 CB VAL F 421 9.792 -8.485 -60.500 1.00 78.54 C ANISOU 5974 CB VAL F 421 7234 13606 9001 -421 -3660 -2651 C ATOM 5975 CG1 VAL F 421 8.878 -7.313 -60.807 1.00 82.04 C ANISOU 5975 CG1 VAL F 421 7378 14217 9575 -122 -4060 -2593 C ATOM 5976 CG2 VAL F 421 9.832 -9.491 -61.650 1.00 80.93 C ANISOU 5976 CG2 VAL F 421 7719 14022 9009 -611 -3856 -2839 C ATOM 5977 C VAL F 421 11.256 -6.621 -59.499 1.00 73.25 C ANISOU 5977 C VAL F 421 6923 12642 8268 -29 -3339 -2091 C ATOM 5978 O VAL F 421 11.324 -6.490 -58.270 1.00 71.13 O ANISOU 5978 O VAL F 421 6541 12226 8260 -56 -3019 -2067 O ATOM 5979 N ASN F 422 11.235 -5.578 -60.335 1.00 75.33 N ANISOU 5979 N ASN F 422 7301 12982 8339 236 -3678 -1903 N ATOM 5980 CA ASN F 422 11.155 -4.182 -59.848 1.00 75.16 C ANISOU 5980 CA ASN F 422 7234 12867 8457 526 -3716 -1678 C ATOM 5981 CB ASN F 422 11.971 -3.211 -60.732 1.00 75.42 C ANISOU 5981 CB ASN F 422 7709 12848 8099 726 -3890 -1361 C ATOM 5982 CG ASN F 422 11.733 -3.403 -62.234 1.00 78.66 C ANISOU 5982 CG ASN F 422 8283 13451 8152 754 -4312 -1386 C ATOM 5983 OD1 ASN F 422 12.644 -3.194 -63.032 1.00 78.39 O ANISOU 5983 OD1 ASN F 422 8691 13389 7703 758 -4323 -1195 O ATOM 5984 ND2 ASN F 422 10.515 -3.784 -62.621 1.00 82.48 N ANISOU 5984 ND2 ASN F 422 8411 14140 8786 763 -4655 -1629 N ATOM 5985 C ASN F 422 9.730 -3.647 -59.623 1.00 78.75 C ANISOU 5985 C ASN F 422 7196 13446 9279 707 -3985 -1818 C ATOM 5986 O ASN F 422 8.770 -4.093 -60.259 1.00 82.55 O ANISOU 5986 O ASN F 422 7398 14147 9820 676 -4307 -2041 O ATOM 5987 N ASN F 425 7.024 -4.833 -63.856 1.00 98.86 N ANISOU 5987 N ASN F 425 9351 16900 11312 750 -5734 -2397 N ATOM 5988 CA ASN F 425 7.135 -6.277 -63.620 1.00 97.53 C ANISOU 5988 CA ASN F 425 9123 16747 11187 326 -5436 -2676 C ATOM 5989 CB ASN F 425 5.828 -6.981 -64.027 1.00102.75 C ANISOU 5989 CB ASN F 425 9296 17692 12053 177 -5785 -3064 C ATOM 5990 CG ASN F 425 5.624 -8.316 -63.314 1.00102.31 C ANISOU 5990 CG ASN F 425 9017 17603 12253 -265 -5400 -3381 C ATOM 5991 OD1 ASN F 425 5.938 -8.463 -62.125 1.00 99.34 O ANISOU 5991 OD1 ASN F 425 8595 17029 12122 -377 -4908 -3350 O ATOM 5992 ND2 ASN F 425 5.084 -9.292 -64.040 1.00106.55 N ANISOU 5992 ND2 ASN F 425 9446 18321 12716 -527 -5632 -3690 N ATOM 5993 C ASN F 425 8.361 -6.918 -64.312 1.00 94.87 C ANISOU 5993 C ASN F 425 9373 16317 10355 150 -5275 -2581 C ATOM 5994 O ASN F 425 8.342 -8.097 -64.685 1.00 95.60 O ANISOU 5994 O ASN F 425 9505 16474 10347 -145 -5240 -2830 O ATOM 5995 N GLN F 426 9.430 -6.136 -64.450 1.00 91.71 N ANISOU 5995 N GLN F 426 9420 15760 9667 322 -5153 -2238 N ATOM 5996 CA GLN F 426 10.599 -6.536 -65.229 1.00 89.89 C ANISOU 5996 CA GLN F 426 9732 15477 8946 211 -5027 -2133 C ATOM 5997 CB GLN F 426 11.215 -5.312 -65.891 1.00 90.44 C ANISOU 5997 CB GLN F 426 10206 15499 8656 478 -5188 -1769 C ATOM 5998 CG GLN F 426 10.299 -4.689 -66.940 1.00 97.68 C ANISOU 5998 CG GLN F 426 11101 16610 9404 704 -5808 -1744 C ATOM 5999 CD GLN F 426 10.355 -3.172 -66.960 1.00 99.86 C ANISOU 5999 CD GLN F 426 11537 16771 9635 1056 -5984 -1390 C ATOM 6000 OE1 GLN F 426 10.705 -2.530 -65.963 1.00 97.48 O ANISOU 6000 OE1 GLN F 426 11179 16268 9590 1145 -5681 -1230 O ATOM 6001 NE2 GLN F 426 9.997 -2.588 -68.101 1.00105.16 N ANISOU 6001 NE2 GLN F 426 12440 17552 9963 1259 -6492 -1268 N ATOM 6002 C GLN F 426 11.620 -7.231 -64.357 1.00 84.44 C ANISOU 6002 C GLN F 426 9182 14578 832.

4. 4459 -2135 C ATOM 6003 O GLN F 426 11.740 -6.912 -63.176 1.00 81.85 O ANISOU 6003 O GLN F 426 8691 14096 831.

37. 4164 -2056 O ATOM 6004 N ARG F 427 12.359 -8.169 -64.948 1.00 83.25 N ANISOU 6004 N ARG F 427 9349 14421 7862 -189 -4319 -2232 N ATOM 6005 CA ARG F 427 13.309 -9.025 -64.224 1.00 78.32 C ANISOU 6005 CA ARG F 427 8863 13606 7291 -373 -3826 -2279 C ATOM 6006 CB ARG F 427 13.485 -10.355 -64.972 1.00 80.10 C ANISOU 6006 CB ARG F 427 9276 13874 7285 -608 -3811 -2550 C ATOM 6007 CG ARG F 427 14.098 -11.462 -64.139 1.00 76.56 C ANISOU 6007 CG ARG F 427 8883 13214 6993 -803 -3370 -2682 C ATOM 6008 CD ARG F 427 14.519 -12.666 -64.971 1.00 77.87 C ANISOU 6008 CD ARG F 427 9339 13376 6870 -982 -3325 -2916 C ATOM 6009 NE ARG F 427 15.694 -13.289 -64.368 1.00 73.46 N ANISOU 6009 NE ARG F 427 9005 12591 6315 -1013 -2884 -2889 N ATOM 6010 CZ ARG F 427 15.669 -14.203 -63.397 1.00 71.27 C ANISOU 6010 CZ ARG F 427 8652 12105 6323 -1165 -2616 -3026 C ATOM 6011 NH1 ARG F 427 14.518 -14.649 -62.913 1.00 72.31 N ANISOU 6011 NH1 ARG F 427 8487 12227 6763 -1350 -2697 -3217 N ATOM 6012 NH2 ARG F 427 16.809 -14.675 -62.908 1.00 67.90 N ANISOU 6012 NH2 ARG F 427 8452 11478 5871 -1132 -2266 -2974 N ATOM 6013 C ARG F 427 14.672 -8.348 -64.009 1.00 74.70 C

ANISOU 6013 C ARG F 427 8734 13001 6647 -251 -3533 -1973 C

ATOM 6014 O ARG F 427 15.300 -7.904 -64.973 1.00 75.87 O

ANISOU 6014 O ARG F 427 9220 13212 6395 -172 -3625 -1821 O

ATOM 6015 N LEU F 428 15.131 -8.282 -62.758 1.00 70.08 N

ANISOU 6015 N LEU F 428 8058 12231 6337 -257 -3177 -1893 N

ATOM 6016 CA LEU F 428 16.419 -7.647 -62.441 1.00 66.81 C

ANISOU 6016 CA LEU F 428 7899 11689 5796 -165 -2899 -1630 C

ATOM 6017 CB LEU F 428 16.562 -7.399 -60.921 1.00 63.57 C

ANISOU 6017 CB LEU F 428 7303 11097 5755 -149 -2609 -1557 C

ATOM 6018 CG LEU F 428 15.516 -6.574 -60.147 1.00 63.89 C

ANISOU 6018 CG LEU F 428 7011 11121 6144 -34 -2730 -1518 C

ATOM 6019 CD1 LEU F 428 15.697 -6.733 -58.634 1.00 62.28 C

ANISOU 6019 CD1 LEU F 428 6672 10736 6257 -96 -2381 -1524 C

ATOM 6020 CD2 LEU F 428 15.535 -5.103 -60.527 1.00 64.62 C

ANISOU 6020 CD2 LEU F 428 7197 11227 6130 203 -2935 -1253 C

ATOM 6021 C LEU F 428 17.636 -8.433 -62.980 1.00 65.60 C

ANISOU 6021 C LEU F 428 8076 11517 5330 -268 -2664 -1675 C

ATOM 6022 O LEU F 428 17.516 -9.608 -63.330 1.00 66.61 O

ANISOU 6022 O LEU F 428 8239 11668 5402 -417 -2648 -1925 O

ATOM 6023 N ASN F 429 18.796 -7.770 -63.056 1.00 63.59 N

ANISOU 6023 N ASN F 429 8056 11222 4884 -191 -2477 -1450 N

ATOM 6024 CA ASN F 429 20.054 -8.420 -63.463 1.00 62.44 C

ANISOU 6024 CA ASN F 429 8171 11070 4485 -261 -2205 -1496 C

ATOM 6025 CB ASN F 429 21.027 -7.413 -64.103 1.00 63.01 C

ANISOU 6025 CB ASN F 429 8510 11197 4233 -193 -2135 -1245 C

ATOM 6026 CG ASN F 429 21.529 -6.363 -63.128 1.00 60.93 C

ANISOU 6026 CG ASN F 429 8175 10809 4167 -113 -1976 -998 C

ATOM 6027 OD1 ASN F 429 22.477 -6.593 -62.368 1.00 58.51 O

ANISOU 6027 OD1 ASN F 429 7839 10412 3980 -137 -1668 -990 O

ATOM 6028 ND2 ASN F 429 20.914 -5.187 -63.169 1.00 62.71 N

ANISOU 6028 ND2 ASN F 429 8387 11023 4418 -6 -2203 -799 N

ATOM 6029 C ASN F 429 20.718 -9.203 -62.314 1.00 58.73 C

ANISOU 6029 C ASN F 429 7615 10428 4271 -309 -1860 -1579 C

ATOM 6030 O ASN F 429 20.508 -8.869 -61.159 1.00 56.33 O

ANISOU 6030 O ASN F 429 7122 10004 4278 -277 -1781 -1501 O

ATOM 6031 N PRO F 430 21.502 -10.253 -62.639 1.00 58.55 N

ANISOU 6031 N PRO F 430 7752 10388 4107 -370 -1665 -1747 N

ATOM 6032 CA PRO F 430 22.103 -11.214 -61.701 1.00 56.25 C

ANISOU 6032 CA PRO F 430 7432 9919 4022 -392 -1387 -1860 C

ATOM 6033 CB PRO F 430 23.143 -11.919 -62.569 1.00 57.92 C

ANISOU 6033 CB PRO F 430 7882 10184 3943 -387 -1225 -1989 C

ATOM 6034 CG PRO F 430 22.512 -11.934 -63.934 1.00 61.22 C

ANISOU 6034 CG PRO F 430 8436 10778 4048 -454 -1472 -2086 C

ATOM 6035 CD PRO F 430 21.832 -10.598 -64.041 1.00 61.60 C

ANISOU 6035 CD PRO F 430 8395 10925 4087 -406 -1721 -1851 C

ATOM 6036 C PRO F 430 22.770 -10.649 -60.433 1.00 53.25 C

ANISOU 6036 C PRO F 430 6949 9412 3872 -310 -1184 -1672 C

ATOM 6037 O PRO F 430 22.727 -11.279 -59.364 1.00 51.32 O

ANISOU 6037 O PRO F 430 6623 8994 3881 -331 -1058 -1737 O

ATOM 6038 N MSE F 431 23.393 -9.482 -60.550 1.00 52.56 N

ANISOU 6038 N MSE F 431 6896 9398 3678 -235 -1153 -1444 N

ATOM 6039 CA MSE F 431 24.056 -8.867 -59.414 1.00 49.48 C

ANISOU 6039 CA MSE F 431 6418 8904 3479 -176 -983 -1278 C

ATOM 6040 CB MSE F 431 25.096 -7.852 -59.885 1.00 49.34 C

ANISOU 6040 CB MSE F 431 6508 8987 3253 -144 -888 -1088 C

ATOM 6041 CG MSE F 431 26.338 -8.505 -60.487 1.00 49.79 C

ANISOU 6041 CG MSE F 431 6683 9129 3106 -146 -670 -1196 C

ATOM 6042 SE MSE F 431 27.421 -9.500 -59.208 0.90 48.52 SE

ANISOU 6042 SE MSE F 431 6408 8820 3206 -65 -407 -1314 SE

ATOM 6043 CE MSE F 431 28.095 -8.003 -58.164 1.00 42.60 C

ANISOU 6043 CE MSE F 431 5533 8047 2607 -51 -331 -1034 C

ATOM 6044 C MSE F 431 23.033 -8.245 -58.467 1.00 48.53 C

ANISOU 6044 C MSE F 431 6111 8689 3637 -167 -1099 -1191 C

ATOM 6045 O MSE F 431 23.151 -8.389 -57.249 1.00 46.67 O

ANISOU 6045 O MSE F 431 5784 8310 3637 -162 -966 -1179 O

ATOM 6046 N HIS F 432 22.022 -7.577 -59.025 1.00 50.21 N

ANISOU 6046 N HIS F 432 6275 8987 3817 -152 -1351 -1142 N

ATOM 6047 CA HIS F 432 20.939 -6.996 -58.216 1.00 50.13 C

ANISOU 6047 CA HIS F 432 6049 8909 4088 -120 -1466 -1100 C

ATOM 6048 CB HIS F 432 20.214 -5.876 -58.970 1.00 52.12 C

ANISOU 6048 CB HIS F 432 6294 9261 4248 -24 -1753 -971 C

ATOM 6049 CG HIS F 432 21.028 -4.628 -59.064 1.00 53.16 C

ANISOU 6049 CG HIS F 432 6589 9363 424.

57. 1703 -709 C

ATOM 6050 ND1 HIS F 432 21.765 -4.303 -60.183 1.00 56.08 N

ANISOU 6050 ND1 HIS F 432 7218 9830 425.

47. 1719 -603 N

ATOM 6051 CE1 HIS F 432 22.416 -3.175 -59.964 1.00 55.82 C

ANISOU 6051 CE1 HIS F 432 7296 9724 418.

81. 1633 -377 C

ATOM 6052 NE2 HIS F 432 22.146 -2.768 -58.736 1.00 53.78 N

ANISOU 6052 NE2 HIS F 432 6864 9325 4245 128 -1574 -342 N

ATOM 6053 CD2 HIS F 432 21.287 -3.664 -58.149 1.00 52.46 C

ANISOU 6053 CD2 HIS F 432 6466 9146 4318 116 -1604 -545 C

ATOM 6054 C HIS F 432 19.976 -8.044 -57.680 1.00 50.25 C

ANISOU 6054 C HIS F 432 5890 8868 4334 -223 -1472 -1325 C

ATOM 6055 O HIS F 432 19.291 -7.825 -56.678 1.00 49.54 O

ANISOU 6055 O HIS F 432 5610 8692 4520 -230 -1440 -1330 O

ATOM 6056 N GLN F 433 19.961 -9.185 -58.363 1.00 51.26 N

ANISOU 6056 N GLN F 433 6103 9036 4336 -321 -1489 -1523 N

ATOM 6057 CA GLN F 433 19.267 -10.386 -57.940 1.00 51.44 C

ANISOU 6057 CA GLN F 433 6036 8972 4537 -471 -1445 -1757 C

ATOM 6058 CB GLN F 433 19.368 -11.415 -59.072 1.00 53.59 C

ANISOU 6058 CB GLN F 433 6472 9312 4577 -558 -1515 -1959 C

ATOM 6059 CG GLN F 433 18.243 -12.401 -59.174 1.00 56.54 C

ANISOU 6059 CG GLN F 433 6733 9673 5078 -746 -1618 -2223 C

ATOM 6060 CD GLN F 433 16.932 -11.816 -59.689 1.00 59.82 C

ANISOU 6060 CD GLN F 433 6898 10278 5554 -765 -1945 -2270 C

ATOM 6061 OE1 GLN F 433 15.859 -12.218 -59.245 1.00 61.27 O

ANISOU 6061 OE1 GLN F 433 6840 10449 5990 -910 -1990 -2434 O

ATOM 6062 NE2 GLN F 433 17.012 -10.890 -60.639 1.00 62.13 N

ANISOU 6062 NE2 GLN F 433 7249 10744 5612 -622 -2176 -2135 N

ATOM 6063 C GLN F 433 19.878 -10.921 -56.630 1.00 48.94 C

ANISOU 6063 C GLN F 433 5764 8437 4393 -497 -1154 -1743 C

ATOM 6064 O GLN F 433 19.161 -11.164 -55.657 1.00 48.75 O

ANISOU 6064 O GLN F 433 5604 8301 4617 -588 -1080 -1799 O

ATOM 6065 N LEU F 434 21.204 -11.080 -56.605 1.00 47.33 N

ANISOU 6065 N LEU F 434 5750 8183 4051 -415 -991 -1671 N

ATOM 6066 CA LEU F 434 21.915 -11.611 -55.435 1.00 45.33 C

ANISOU 6066 CA LEU F 434 5572 7729 3923 -399 -763 -1651 C

ATOM 6067 CB LEU F 434 23.375 -11.926 -55.764 1.00 44.35 C

ANISOU 6067 CB LEU F 434 5621 7609 3622 -286 -638 -1633 C

ATOM 6068 CG LEU F 434 23.737 -13.106 -56.671 1.00 46.26 C

ANISOU 6068 CG LEU F 434 6031 7847 3701 -298 -613 -1839 C

ATOM 6069 CD1 LEU F 434 25.048 -12.834 -57.429 1.00 45.03 C

ANISOU 6069 CD1 LEU F 434 5961 7831 3320 -170 -529 -1797 C

ATOM 6070 CD2 LEU F 434 23.811 -14.406 -55.887 1.00 45.64 C

ANISOU 6070 CD2 LEU F 434 6075 7510 3756 -328 -486 -1973 C

ATOM 6071 C LEU F 434 21.877 -10.621 -54.289 1.00 43.61 C

ANISOU 6071 C LEU F 434 5240 7453 3875 -350 -703 -1470 C

ATOM 6072 O LEU F 434 21.795 -11.014 -53.136 1.00 42.36 O

ANISOU 6072 O LEU F 434 5094 7124 3877 -394 -569 -1478 O

ATOM 6073 N LEU F 435 21.949 -9.337 -54.633 1.00 43.83 N

ANISOU 6073 N LEU F 435 5202 7609 3845 -265 -801 -1307 N

ATOM 6074 CA LEU F 435 21.877 -8.246 -53.682 1.00 42.80 C

ANISOU 6074 CA LEU F 435 4980 7425 3858 -212 -765 -1145 C

ATOM 6075 CB LEU F 435 22.151 -6.916 -54.393 1.00 43.44 C

ANISOU 6075 CB LEU F 435 5072 7627 3806 -118 -883 -969 C

ATOM 6076 CG LEU F 435 22.046 -5.590 -53.631 1.00 43.35 C

ANISOU 6076 CG LEU F 435 4998 7552 3919 -51 -879 -798 C

ATOM 6077 CD1 LEU F 435 23.280 -5.323 -52.808 1.00 40.78 C

ANISOU 6077 CD1 LEU F 435 4764 7145 3587 -39 -699 -695 C ATOM 6078 CD2 LEU F 435 21.811 -4.465 -54.623 1.00 46.94 C ANISOU 6078 CD2 LEU F 435 5485 8107 4244.

28. 1070 -665 C ATOM 6079 C LEU F 435 20.548 -8.204 -52.917 1.00 43.61 C ANISOU 6079 C LEU F 435 4899 7464 4207 -283 -781 -1217 C ATOM 6080 O LEU F 435 20.564 -8.107 -51.684 1.00 43.27 O ANISOU 6080 O LEU F 435 4845 7285 4311 -301 -630 -1181 O ATOM 6081 N ARG F 436 19.419 -8.281 -53.628 1.00 45.19 N ANISOU 6081 N ARG F 436 4950 7774 4447 -327 -958 -1331 N ATOM 6082 CA ARG F 436 18.092 -8.308 -52.997 1.00 46.39 C ANISOU 6082 CA ARG F 436 4861 7907 4858 -409 -963 -1447 C ATOM 6083 CB ARG F 436 16.958 -8.209 -54.025 1.00 49.83 C ANISOU 6083 CB ARG F 436 5092 8525 5315 -416 -1236 -1567 C ATOM 6084 CG ARG F 436 16.930 -6.953 -54.854 1.00 52.80 C ANISOU 6084 CG ARG F 436 5452 9031 5579 -222 -1482 -1411 C ATOM 6085 CD ARG F 436 16.008 -5.894 -54.293 1.00 58.94 C ANISOU 6085 CD ARG F 436 5980 9814 6599 -104 -1555 -1371 C ATOM 6086 NE ARG F 436 15.996 -4.730 -55.183 1.00 65.22 N ANISOU 6086 NE ARG F 436 6825 10696 7261.

100. 1823 -1207 N ATOM 6087 CZ ARG F 436 16.971 -3.816 -55.263 1.00 66.83 C ANISOU 6087 CZ ARG F 436 7266 10826 7300 211 -1789 -971 C ATOM 6088 NH1 ARG F 436 18.065 -3.900 -54.498 1.00 64.44 N ANISOU 6088 NH1 ARG F 436 7128 10393 6962 150 -1516 -886 N ATOM 6089 NH2 ARG F 436 16.854 -2.803 -56.124 1.00 69.94 N ANISOU 6089 NH2 ARG F 436 7744 11271 7558 377 -2041 -820 N ATOM 6090 C ARG F 436 17.859 -9.557 -52.166 1.00 45.64 C ANISOU 6090 C ARG F 436 4800 7659 4881 -598 -758 -1602 C ATOM 6091 O ARG F 436 17.216 -9.476 -51.121 1.00 45.62 O ANISOU 6091 O ARG F 436 4679 7574 5082 -674 -619 -1635 O ATOM 6092 N HIS F 437 18.342 -10.706 -52.646 1.00 45.31 N ANISOU 6092 N HIS F 437 4943 7568 4705 -678 -729 -1703 N ATOM 6093 CA HIS F 437 18.235 -11.973 -51.907 1.00 45.24 C ANISOU 6093 CA HIS F 437 5056 7358 4776 -856 -535 -1833 C ATOM 6094 CB HIS F 437 18.834 -13.126 -52.703 1.00 45.82 C ANISOU 6094 CB HIS F 437 5355 7378 4675 -890 -550 -1948 C ATOM 6095 CG HIS F 437 18.890 -14.416 -51.941 1.00 46.87 C ANISOU 6095 CG HIS F 437 5698 7245 4866 -1039 -355 -2050 C ATOM 6096 ND1 HIS F 437 17.806 -15.262 -51.828 1.00 50.23 N ANISOU 6096 ND1 HIS F 437 6073 7589 5423 -1302 -309 -2247 N ATOM 6097 CE1 HIS F 437 18.145 -16.317 -51.107 1.00 49.92 C ANISOU 6097 CE1 HIS F 437 6317 7264 5387 -1394 -120 -2277 C ATOM 6098 NE2 HIS F 437 19.407 -16.186 -50.746 1.00 46.92 N ANISOU 6098 NE2 HIS F 437 6143 6795 4890 -1170 -71 -2113 N ATOM 6099 CD2 HIS F 437 19.897 -15.006 -51.253 1.00 45.46 C ANISOU 6099 CD2 HIS F 437 5796 6848 4628 -964 -203 -1979 C ATOM 6100 C HIS F 437 18.888 -11.907 -50.513 1.00 43.18 C ANISOU 6100 C HIS F 437 4945 6899 4562 -822 -311 -1700 C ATOM 6101 O HIS F 437 18.278 -12.279 -49.506 1.00 43.17 O ANISOU 6101 O HIS F 437 4939 6759 4706 -972 -145 -1753 O ATOM 6102 N PHE F 438 20.125 -11.420 -50.468 1.00 41.26 N ANISOU 6102 N PHE F 438 4837 6655 4185 -641 -309 -1536 N ATOM 6103 CA PHE F 438 20.852 -11.273 -49.206 1.00 39.83 C ANISOU 6103 CA PHE F 438 4798 6315 4020 -587 -153 -1408 C ATOM 6104 CB PHE F 438 22.361 -11.316 -49.455 1.00 37.85 C ANISOU 6104 CB PHE F 438 4709 6069 3602 -417 -169 -1313 C ATOM 6105 CG PHE F 438 22.829 -12.660 -49.947 1.00 39.60 C ANISOU 6105 CG PHE F 438 5116 6198 3733 -418 -151 -1439 C ATOM 6106 CD1 PHE F 438 22.572 -13.808 -49.195 1.00 40.19 C ANISOU 6106 CD1 PHE F 438 5380 6026 3864 -522 -35 -1520 C ATOM 6107 CE1 PHE F 438 22.977 -15.070 -49.651 1.00 41.92 C ANISOU 6107 CE1 PHE F 438 5806 6113 4007 -509 -21 -1646 C ATOM 6108 CZ PHE F 438 23.645 -15.183 -50.862 1.00 41.42 C ANISOU 6108 CZ PHE F 438 5733 6193 3811 -388 -107 -1710 C ATOM 6109 CE2 PHE F 438 23.898 -14.046 -51.625 1.00 40.68 C ANISOU 6109 CE2 PHE F 438 5446 6370 3640 -307 -203 -1629 C ATOM 6110 CD2 PHE F 438 23.490 -12.793 -51.171 1.00 37.92 C ANISOU 6110 CD2 PHE F 438 4917 6123 3367 -324 -234 -1485 C ATOM 6111 C PHE F 438 20.402 -10.089 -48.336 1.00 39.24 C ANISOU 6111 C PHE F 438 4583 6259 4070 -568 -108 -1305 C ATOM 6112 O PHE F 438 20.540 -10.130 -47.106 1.00 39.25 O ANISOU 6112 O PHE F 438 4694 6107 4112 -601.

45. 1255 O ATOM 6113 N GLN F 439 19.858 -9.049 -48.967 1.00 39.55 N ANISOU 6113 N GLN F 439 4408 6467 4154 -505 -247 -1277 N ATOM 6114 CA GLN F 439 19.215 -7.958 -48.236 1.00 40.07 C ANISOU 6114 CA GLN F 439 4319 6538 4370 -476 -210 -1224 C ATOM 6115 CB GLN F 439 18.927 -6.776 -49.172 1.00 40.77 C ANISOU 6115 CB GLN F 439 4244 6792 4456 -335 -421 -1156 C ATOM 6116 CG GLN F 439 20.154 -5.878 -49.485 1.00 38.76 C ANISOU 6116 CG GLN F 439 4134 6557 4035 -195 -480 -960 C ATOM 6117 CD GLN F 439 19.884 -4.831 -50.591 1.00 40.21 C ANISOU 6117 CD GLN F 439 4240 6875 4164 -74 -700 -876 C ATOM 6118 OE1 GLN F 439 18.910 -4.924 -51.358 1.00 40.53 O ANISOU 6118 OE1 GLN F 439 4129 7024 4247 -65 -866 -967 O ATOM 6119 NE2 GLN F 439 20.765 -3.840 -50.676 1.00 38.72 N ANISOU 6119 NE2 GLN F 439 4173 6671 386.

12. 714 -700 N ATOM 6120 C GLN F 439 17.937 -8.415 -47.506 1.00 41.99 C ANISOU 6120 C GLN F 439 4418 6725 4813 -648 -69 -1382 C ATOM 6121 O GLN F 439 17.606 -7.892 -46.434 1.00 42.49 O ANISOU 6121 O GLN F 439 4446 6713 4984 -664.

82. 1362 O ATOM 6122 N LYS F 440 17.235 -9.393 -48.079 1.00 43.71 N ANISOU 6122 N LYS F 440 4556 6978 5073 -798 -100 -1554 N ATOM 6123 CA LYS F 440 16.025 -9.948 -47.471 1.00 45.70 C ANISOU 6123 CA LYS F 440 4653 7190 5520 -1019.

59. 1732 C ATOM 6124 CB LYS F 440 15.193 -10.701 -48.516 1.00 47.97 C ANISOU 6124 CB LYS F 440 4765 7600 5862 -1159 -81 -1933 C ATOM 6125 CG LYS F 440 13.730 -10.810 -48.165 1.00 52.65 C ANISOU 6125 CG LYS F 440 5024 8266 6716 -1355.

10. 2138 C ATOM 6126 CD LYS F 440 13.005 -11.813 -49.037 1.00 57.78 C ANISOU 6126 CD LYS F 440 5548 8998 7410 -1567 -98 -2366 C ATOM 6127 CE LYS F 440 11.613 -12.094 -48.466 1.00 63.15 C ANISOU 6127 CE LYS F 440 5897 9727 8371 -1834.

73. 2594 C ATOM 6128 NZ LYS F 440 10.726 -12.860 -49.401 1.00 67.40 N ANISOU 6128 NZ LYS F 440 6202 10408 8999 -2047 -88 -2852 N ATOM 6129 C LYS F 440 16.343 -10.851 -46.265 1.00 45.04 C ANISOU 6129 C LYS F 440 4857 6858 5399 -1184 337 -1726 C ATOM 6130 O LYS F 440 15.665 -10.779 -45.235 1.00 45.28 O ANISOU 6130 O LYS F 440 4834 6818 5553 -1319 556 -1776 O ATOM 6131 N ASP F 441 17.363 -11.702 -46.407 1.00 44.15 N ANISOU 6131 N ASP F 441 5059 6609 5107 -1164 329 -1670 N ATOM 6132 CA ASP F 441 17.851 -12.542 -45.301 1.00 44.37 C ANISOU 6132 CA ASP F 441 5434 6370 5057 -1258 537 -1623 C ATOM 6133 CB ASP F 441 17.083 -13.877 -45.220 1.00 47.39 C ANISOU 6133 CB ASP F 441 5912 6599 5494 -1550 681 -1796 C ATOM 6134 CG ASP F 441 17.580 -14.785 -44.081 1.00 49.62 C ANISOU 6134 CG ASP F 441 6630 6558 5663 -1643 885 -1723 C ATOM 6135 OD1 ASP F 441 17.900 -14.261 -42.985 1.00 47.18 O ANISOU 6135 OD1 ASP F 441 6449 6174 5305 -1586 997 -1590 O ATOM 6136 OD2 ASP F 441 17.647 -16.033 -44.294 1.00 53.67 O ANISOU 6136 OD2 ASP F 441 7391 6878 6124 -1769 920 -1801 O ATOM 6137 C ASP F 441 19.354 -12.779 -45.422 1.00 42.20 C ANISOU 6137 C ASP F 441 5438 6011 4585 -1054 445 -1484 C ATOM 6138 O ASP F 441 19.809 -13.476 -46.344 1.00 42.70 O ANISOU 6138 O ASP F 441 5580 6080 4565 -1008 336 -1539 O ATOM 6139 N ALA F 442 20.119 -12.200 -44.490 1.00 39.94 N ANISOU 6139 N ALA F 442 5287 5659 4228 -932 490 -1327 N ATOM 6140 CA ALA F 442 21.587 -12.254 -44.552 1.00 37.88 C ANISOU 6140 CA ALA F 442 5212 5367 3812 -718 385 -1206 C ATOM 6141 CB ALA F 442 22.194 -10.935 -44.070 1.00 35.76 C ANISOU 6141 CB ALA F 442 4870 5197 3522 -576 341 -1061 C ATOM 6142 C ALA F 442 22.206 -13.431 -43.786 1.00 38.27 C ANISOU 6142 C ALA F 442 5637 5147 3758 -720 460 -1181 C ATOM 6143 O ALA F 442 23.427 -13.627 -43.815 1.00 37.55 O ANISOU 6143 O ALA F 442 5683 5026 3559 -521 361 -1107 O ATOM 6144 N LYS F 443 21.364 -14.209 -43.117 1.00 39.15 N ANISOU 6144 N LYS F 443 5911 5060 3903 -941 634 -1246 N ATOM 6145 CA LYS F 443 21.830 -15.168 -42.119 1.00 40.19 C ANISOU 6145 CA LYS F 443 6467 4887 3916 -956 722 -1181 C ATOM 6146 CB LYS F 443 20.647 -15.777 -41.368 1.00 42.67 C ANISOU 6146 CB LYS F 443 6926 5010 4276 -1279 972 -1253 C ATOM 6147 CG LYS F 443 20.361 -15.115 -40.038 1.00 42.60 C ANISOU 6147 CG LYS F 443 7000 4958 4230 -1361 1138 -1163 C ATOM 6148 CD LYS F 443 19.175 -15.766 -39.380 1.00 45.79 C ANISOU 6148 CD LYS F 443 7535 5190 4676 -1716 1431 -1256 C ATOM 6149 CE LYS F 443 17.886 -15.276 -40.009 1.00 47.38 C ANISOU 6149 CE LYS F 443 7261 5629 5111 -1902 1514 -1439 C ATOM 6150 NZ LYS F 443 17.018 -16.416 -40.328 1.00 51.45 N ANISOU 6150 NZ LYS F 443 7824 6016 5707 -2211 1655 -1602 N ATOM 6151 C LYS F 443 22.727 -16.272 -42.669 1.00 40.29 C ANISOU 6151 C LYS F 443 6714 4754 3841 -804 609 -1201 C ATOM 6152 O LYS F 443 23.776 -16.559 -42.095 1.00 39.70 O ANISOU 6152 O LYS F 443 6892 4543 3650 -607 536 -1092 O ATOM 6153 N VAL F 444 22.306 -16.894 -43.771 1.00 40.93 N ANISOU 6153 N VAL F 444 6708 4865 3980 -884 583 -1356 N ATOM 6154 CA VAL F 444 23.106 -17.948 -44.424 1.00 41.02 C ANISOU 6154 CA VAL F 444 6929 4738 3917 -730 491 -1416 C ATOM 6155 CB VAL F 444 22.315 -18.633 -45.563 1.00 42.70 C ANISOU 6155 CB VAL F 444 7062 4969 4193 -911 498 -1626 C ATOM 6156 CG1 VAL F 444 23.094 -19.832 -46.148 1.00 43.29 C ANISOU 6156 CG1 VAL F 444 7417 4842 4187 -760 438 -1715 C ATOM 6157 CG2 VAL F 444 20.936 -19.073 -45.051 1.00 44.72 C ANISOU 6157 CG2 VAL F 444 7368 5079 4545 -1289 687 -1713 C ATOM 6158 C VAL F 444 24.422 -17.346 -44.942 1.00 38.71 C ANISOU 6158 C VAL F 444 6494 4651 3563 -400 317 -1349 C ATOM 6159 O VAL F 444 25.494 -17.944 -44.813 1.00 39.03 O ANISOU 6159 O VAL F 444 6739 4560 3529 -169 245 -1320 O ATOM 6160 N LEU F 445 24.333 -16.142 -45.489 1.00 36.36 N ANISOU 6160 N LEU F 445 5845 4667 3303 -380 255 -1326 N ATOM 6161 CA LEU F 445 25.508 -15.420 -45.967 1.00 34.90 C ANISOU 6161 CA LEU F 445 5500 4697 3063 -133 131 -1260 C ATOM 6162 CB LEU F 445 25.098 -14.069 -46.554 1.00 32.55 C ANISOU 6162 CB LEU F 445 4867 4693 2805 -184.

89. 1227 C ATOM 6163 CG LEU F 445 26.226 -13.137 -46.999 1.00 31.63 C ANISOU 6163 CG LEU F 445 4587 4801 2630 0 -2 -1143 C ATOM 6164 CD1 LEU F 445 26.905 -13.645 -48.265 1.00 30.39 C ANISOU 6164 CD1 LEU F 445 4401 4755 2391 115 -50 -1248 C ATOM 6165 CD2 LEU F 445 25.692 -11.704 -47.173 1.00 30.43 C ANISOU 6165 CD2 LEU F 445 4199 4843 2521 -73 -28 -1062 C ATOM 6166 C LEU F 445 26.542 -15.233 -44.853 1.00 35.09 C ANISOU 6166 C LEU F 445 5661 4635 3035 4.

94. 1119 C ATOM 6167 O LEU F 445 27.710 -15.627 -44.999 1.00 35.50 O ANISOU 6167 O LEU F 445 5772 4680 3036 27.

8. 1121 O ATOM 6168 N PHE F 446 26.090 -14.642 -43.743 1.00 35.06 N ANISOU 6168 N PHE F 446 5700 4578 3045 -65 157 -1016 N ATOM 6169 CA PHE F 446 26.937 -14.316 -42.610 1.00 35.44 C ANISOU 6169 CA PHE F 446 5879 4565 3023 66 102 -884 C ATOM 6170 CB PHE F 446 26.155 -13.442 -41.604 1.00 33.86 C ANISOU 6170 CB PHE F 446 5673 4356 2836 -109 206 -808 C ATOM 6171 CG PHE F 446 26.103 -11.980 -41.978 1.00 30.18 C ANISOU 6171 CG PHE F 446 4878 4157 2434 -115 174 -779 C ATOM 6172 CD1 PHE F 446 26.572 -11.539 -43.229 1.00 28.69 C ANISOU 6172 CD1 PHE F 446 4433 4194 2273 -20.

77. 809 C ATOM 6173 CE1 PHE F 446 26.527 -10.181 -43.583 1.00 26.71 C ANISOU 6173 CE1 PHE F 446 3939 4146 2063 -34.

47. 761 C ATOM 6174 CZ PHE F 446 25.987 -9.247 -42.674 1.00 27.01 C ANISOU 6174 CZ PHE F 446 3967 4156 2138 -123 111 -702 C ATOM 6175 CE2 PHE F 446 25.498 -9.688 -41.439 1.00 24.47 C ANISOU 6175 CE2 PHE F 446 3871 3634 1792 -215 223 -696 C ATOM 6176 CD2 PHE F 446 25.556 -11.045 -41.101 1.00 28.12 C ANISOU 6176 CD2 PHE F 446 4595 3899 2192 -223 257 -724 C ATOM 6177 C PHE F 446 27.501 -15.562 -41.943 1.00 38.56 C ANISOU 6177 C PHE F 446 6654 4667 3332 19.

66. 864 C ATOM 6178 O PHE F 446 28.671 -15.593 -41.562 1.00 39.82 O ANISOU 6178 O PHE F 446 6870 4828 3433 430 -77 -804 O ATOM 6179 N GLN F 447 26.677 -16.596 -41.820 1.00 41.56 N ANISOU 6179 N GLN F 447 7294 4789 3708 31 185 -921 N ATOM 6180 CA GLN F 447 27.057 -17.775 -41.044 1.00 45.64 C ANISOU 6180 CA GLN F 447 8264 4954 4124 121 165 -873 C ATOM 6181 CB GLN F 447 25.815 -18.492 -40.478 1.00 47.48 C ANISOU 6181 CB GLN F 447 8800 4901 4339 -200 378 -890 C ATOM 6182 CG GLN F 447 25.073 -17.727 -39.352 1.00 48.48 C ANISOU 6182 CG GLN F 447 8957 5035 4427 -424 529 -798 C ATOM 6183 CD GLN F 447 23.680 -18.313 -39.041 1.00 50.68 C ANISOU 6183 CD GLN F 447 9403 5119 4735 -807 800 -867 C ATOM 6184 OE1 GLN F 447 23.423 -19.504 -39.267 1.00 54.85 O ANISOU 6184 OE1 GLN F 447 10205 5382 5253 -905 862 -931 O ATOM 6185 NE2 GLN F 447 22.781 -17.469 -38.526 1.00 51.31 N ANISOU 6185 NE2 GLN F 447 9309 5325 4860 -1031 975 -872 N ATOM 6186 C GLN F 447 27.949 -18.752 -41.824 1.00 47.16 C ANISOU 6186 C GLN F 447 8540 5061 4318 38.

43. 961 C ATOM 6187 O GLN F 447 28.431 -19.731 -41.252 1.00 49.81 O ANISOU 6187 O GLN F 447 9258 5091 4576 537 -19 -919 O ATOM 6188 N ASN F 448 28.178 -18.487 -43.112 1.00 46.16 N ANISOU 6188 N ASN F 448 8083 5190 4265 45.

9. 1083 N ATOM 6189 CA ASN F 448 29.028 -19.362 -43.933 1.00 47.96 C ANISOU 6189 CA ASN F 448 8359 5368 4497 707 -74 -1202 C ATOM 6190 CB ASN F 448 28.210 -20.041 -45.037 1.00 48.76 C ANISOU 6190 CB ASN F 448 8474 5419 4635 53.

28. 1384 C ATOM 6191 CG ASN F 448 27.331 -21.142 -44.506 1.00 51.36 C ANISOU 6191 CG ASN F 448 9217 5346 4949 321 138 -1405 C ATOM 6192 OD1 ASN F 448 27.684 -22.318 -44.583 1.00 56.22 O ANISOU 6192 OD1 ASN F 448 10163 5660 5540 452 119 -1474 O ATOM 6193 ND2 ASN F 448 26.186 -20.775 -43.948 1.00 51.17 N ANISOU 6193 ND2 ASN F 448 9191 5303 4948 -10 270 -1356 N ATOM 6194 C ASN F 448 30.261 -18.680 -44.526 1.00 47.16 C ANISOU 6194 C ASN F 448 7915 5590 4414 975 -193 -1223 C ATOM 6195 O ASN F 448 31.074 -19.318 -45.229 1.00 48.80 O ANISOU 6195 O ASN F 448 8107 5803 4633 1217 -243 -1344 O ATOM 6196 N TRP F 449 30.404 -17.396 -44.214 1.00 44.74 N ANISOU 6196 N TRP F 449 7344 5542 4115 923 -220 -1118 N ATOM 6197 CA TRP F 449 31.462 -16.558 -44.749 1.00 43.75 C ANISOU 6197 CA TRP F 449 6866 5746 4011 1087 -296 -1130 C ATOM 6198 CB TRP F 449 31.109 -15.093 -44.514 1.00 40.74 C ANISOU 6198 CB TRP F 449 6250 5589 3640 899 -272 -1021 C ATOM 6199 CG TRP F 449 32.099 -14.109 -45.064 1.00 39.18 C ANISOU 6199 CG TRP F 449 5708 5720 3459 989 -319 -1021 C ATOM 6200 CD1 TRP F 449 33.122 -13.516 -44.388 1.00 38.41 C ANISOU 6200 CD1 TRP F 449 5492 5733 3368 1111 -427 -956 C ATOM 6201 NE1 TRP F 449 33.798 -12.649 -45.215 1.00 37.76 N ANISOU 6201 NE1 TRP F 449 5082 5959 3306 1105 -405 -988 N ATOM 6202 CE2 TRP F 449 33.212 -12.668 -46.456 1.00 38.35 C ANISOU 6202 CE2 TRP F 449 5092 6121 3360 997 -290 -1060 C ATOM 6203 CD2 TRP F 449 32.132 -13.577 -46.398 1.00 38.04 C ANISOU 6203 CD2 TRP F 449 5310 5833 3311 927 -251 -1092 C ATOM 6204 CE3 TRP F 449 31.347 -13.773 -47.545 1.00 37.88 C ANISOU 6204 CE3 TRP F 449 5272 5859 3262 804 -169 -1181 C ATOM 6205 CZ3 TRP F 449 31.668 -13.069 -48.703 1.00 37.87 C ANISOU 6205 CZ3 TRP F 449 5043 6135 3213 771 -130 -1214 C ATOM 6206 CH2 TRP F 449 32.756 -12.173 -48.731 1.00 37.69 C ANISOU 6206 CH2 TRP F 449 4797 6336 3188 831 -137 -1165 C ATOM 6207 CZ2 TRP F 449 33.536 -11.958 -47.622 1.00 37.45 C ANISOU 6207 CZ2 TRP F 449 4735 6279 3216 935 -216 -1098 C ATOM 6208 C TRP F 449 32.844 -16.878 -44.167 1.00 45.96 C ANISOU 6208 C TRP F 449 7170 6002 4289 1417 -454 -1113 C ATOM 6209 O TRP F 449 33.846 -16.885 -44.895 1.00 46.57 O ANISOU 6209 O TRP F 449 7011 6277 4406 1622 -492 -1216 O ATOM 6210 N GLY F 450 32.904 -17.119 -42.858 1.00 47.36 N ANISOU 6210 N GLY F 450 7622 5957 4416 1470 -550 -991 N ATOM 6211 CA GLY F 450 34.169 -17.491 -42.226 1.00 50.09 C ANISOU 6211 CA GLY F 450 8014 6263 4756 1812 -756 -972 C ATOM 6212 C GLY F 450 34.684 -16.523 -41.180 1.00 49.91 C ANISOU 6212 C GLY F 450 7895 6373 4695 1820 -896 -845 C ATOM 6213 O GLY F 450 34.711 -15.310 -41.382 1.00 47.96 O ANISOU 6213 O GLY F 450 7334 6410 4479 1663 -853 -827 O ATOM 6214 N ILE F 451 35.112 -17.089 -40.061 1.00 52.64 N ANISOU 6214 N ILE F 451 8549 6492 4958 2009 -1079 -759 N ATOM 6215 CA ILE F 451 35.602 -16.346 -38.912 1.00 53.25 C ANISOU 6215 CA ILE F 451 8628 6646 4959 2031 -1254 -644 C ATOM 6216 CB ILE F 451 35.053 -16.971 -37.603 1.00 54.82 C ANISOU 6216 CB ILE F 451 9395 6461 4973 1996 -1306 -493 C ATOM 6217 CG1 ILE F 451 33.541 -17.196 -37.695 1.00 53.93 C ANISOU 6217 CG1 ILE F 451 9533 6138 4820 1646 -1016 -464 C ATOM 6218 CD1 ILE F 451 32.730 -15.935 -37.885 1.00 50.90 C ANISOU 6218 CD1 ILE F 451 8876 5986 4479 1312 -825 -462 C ATOM 6219 CG2 ILE F 451 35.374 -16.122 -36.407 1.00 55.21 C ANISOU 6219 CG2 ILE F 451 9489 6589 4899 1957 -1461 -380 C ATOM 6220 C ILE F 451 37.132 -16.370 -38.907 1.00 55.90 C ANISOU 6220 C ILE F 451 8691 7179 5368 2392 -1514 -716 C ATOM 6221 O ILE F 451 37.752 -17.379 -39.291 1.00 58.65 O ANISOU 6221 O ILE F 451 9074 7433 5779 2709 -1607 -809 O ATOM 6222 N GLU F 452 37.737 -15.263 -38.480 1.00 55.67 N ANISOU 6222 N GLU F 452 8380 7424 5347 2344 -1628 -694 N ATOM 6223 CA GLU F 452 39.200 -15.177 -38.353 1.00 58.58 C ANISOU 6223 CA GLU F 452 8434 8023 5801 2651 -1892 -778 C ATOM 6224 CB GLU F 452 39.802 -14.454 -39.564 1.00 57.37 C ANISOU 6224 CB GLU F 452 7708 8270 5820 2597 -1761 -932 C ATOM 6225 CG GLU F 452 39.359 -12.995 -39.696 1.00 53.46 C ANISOU 6225 CG GLU F 452 7007 7989 5316 2209 -1603 -881 C ATOM 6226 CD GLU F 452 40.063 -12.246 -40.809 1.00 54.15 C ANISOU 6226 CD GLU F 452 6579 8455 5541 2140 -1483 -1012 C ATOM 6227 OE1 GLU F 452 40.983 -12.807 -41.443 1.00 57.04 O ANISOU 6227 OE1 GLU F 452 6687 8967 6017 2391 -1514 -1163 O ATOM 6228 OE2 GLU F 452 39.690 -11.080 -41.056 1.00 52.63 O ANISOU 6228 OE2 GLU F 452 6251 8404 5340 1830 -1342 -966 O ATOM 6229 C GLU F 452 39.607 -14.457 -37.070 1.00 59.73 C ANISOU 6229 C GLU F 452 8632 8226 5839 2623 -2130 -681 C ATOM 6230 O GLU F 452 38.882 -13.574 -36.594 1.00 57.59 O ANISOU 6230 O GLU F 452 8458 7952 5471 2304 -2021 -587 O ATOM 6231 N AHIS F 453 40.760 -14.833 -36.519 0.50 63.60 N ANISOU 6231 N AHIS F 453 9051 8768 6344 2968 -2465 -719 N ATOM 6232 N BHIS F 453 40.754 -14.846 -36.516 0.50 63.68 N ANISOU 6232 N BHIS F 453 9067 8774 6353 2970 -2465 -718 N ATOM 6233 CA AHIS F 453 41.336 -14.158 -35.351 0.50 65.33 C ANISOU 6233 CA AHIS F 453 9270 9092 6462 2971 -2752 -662 C ATOM 6234 CA BHIS F 453 41.340 -14.156 -35.367 0.50 65.46 C ANISOU 6234 CA BHIS F 453 9280 9111 6481 2971 -2750 -664 C ATOM 6235 CB AHIS F 453 42.466 -15.006 -34.739 0.50 70.02 C ANISOU 6235 CB AHIS F 453 9906 9644 7055 3446 -3172 -693 C ATOM 6236 CB BHIS F 453 42.520 -14.952 -34.789 0.50 70.22 C ANISOU 6236 CB BHIS F 453 9888 9698 7095 3444 -3170 -705 C ATOM 6237 CG AHIS F 453 42.950 -14.519 -33.405 0.50 71.64 C

ANISOU 6237 CG AHIS F 453 10237 9889 7094 3472 -3522 -618 C

ATOM 6238 CG BHIS F 453 42.131 -16.251 -34.150 0.50 72.40 C

ANISOU 6238 CG BHIS F 453 10795 9514 7199 3687 -3298 -573 C

ATOM 6239 ND1AHIS F 453 44.132 -13.826 -33.248 0.50 73.20 N

ANISOU 6239 ND1AHIS F 453 9938 10466 7409 3561 -3786 -748 N

ATOM 6240 ND1BHIS F 453 41.800 -16.354 -32.815 0.50 73.75 N

ANISOU 6240 ND1BHIS F 453 11506 9424 7089 3657 -3486 -390 N

ATOM 6241 CE1AHIS F 453 44.303 -13.532 -31.971 0.50 74.77 C

ANISOU 6241 CE1AHIS F 453 10403 10611 7394 3557 -4093 -655 C

ATOM 6242 CE1BHIS F 453 41.511 -17.612 -32.531 0.50 76.18 C

ANISOU 6242 CE1BHIS F 453 12349 9316 7280 3883 -3551 -290 C

ATOM 6243 NE2AHIS F 453 43.277 -14.013 -31.292 0.50 73.86 N

ANISOU 6243 NE2AHIS F 453 10957 10092 7013 3469 -4011 -461 N

ATOM 6244 NE2BHIS F 453 41.648 -18.329 -33.632 0.50 76.34 N

ANISOU 6244 NE2BHIS F 453 12183 9314 7510 4069 -3421 -416 N

ATOM 6245 CD2AHIS F 453 42.418 -14.639 -32.164 0.50 71.98 C

ANISOU 6245 CD2AHIS F 453 10857 9646 6844 3407 -3652 -438 C

ATOM 6246 CD2BHIS F 453 42.038 -17.502 -34.658 0.50 73.83 C

ANISOU 6246 CD2BHIS F 453 11192 9429 7433 3954 -3259 -597 C

ATOM 6247 C AHIS F 453 41.856 -12.786 -35.785 0.50 64.34 C

ANISOU 6247 C AHIS F 453 8588 9388 6470 2743 -2688 -765 C

ATOM 6248 C BHIS F 453 41.815 -12.774 -35.816 0.50 64.27 C

ANISOU 6248 C BHIS F 453 8581 9378 6462 2731 -2673 -764 C

ATOM 6249 O AHIS F 453 42.515 -12.669 -36.821 0.50 64.49 O

ANISOU 6249 O AHIS F 453 8133 9680 6690 2808 -2604 -919 O

ATOM 6250 O BHIS F 453 42.409 -12.638 -36.887 0.50 64.21 O

ANISOU 6250 O BHIS F 453 8108 9637 6652 2778 -2569 -914 O

ATOM 6251 N ILE F 454 41.544 -11.752 -35.009 1.00 63.53 N

ANISOU 6251 N ILE F 454 8571 9322 6247 2459 -2702 -686 N

ATOM 6252 CA ILE F 454 41.980 -10.396 -35.349 1.00 63.62 C

ANISOU 6252 CA ILE F 454 8126 9678 6370 2202 -2634 -772 C

ATOM 6253 CB ILE F 454 40.800 -9.375 -35.410 1.00 59.86 C

ANISOU 6253 CB ILE F 454 7791 9130 5822 1781 -2331 -683 C

ATOM 6254 CG1 ILE F 454 40.225 -9.077 -34.026 1.00 59.78 C

ANISOU 6254 CG1 ILE F 454 8229 8907 5579 1656 -2428 -563 C

ATOM 6255 CD1 ILE F 454 38.978 -8.221 -34.069 1.00 56.89 C

ANISOU 6255 CD1 ILE F 454 8015 8437 5162 1302 -2116 -495 C

ATOM 6256 CG2 ILE F 454 39.713 -9.882 -36.346 1.00 57.55 C

ANISOU 6256 CG2 ILE F 454 7631 8673 5561 1711 -2013 -646 C

ATOM 6257 C ILE F 454 43.171 -9.893 -34.513 1.00 67.95 C

ANISOU 6257 C ILE F 454 8445 10453 6920 2290 -2997 -844 C

ATOM 6258 O ILE F 454 43.466 -10.413 -33.431 1.00 70.35 O

ANISOU 6258 O ILE F 454 9035 10620 7074 2507 -3324 -789 O

ATOM 6259 N ASP F 455 43.850 -8.885 -35.059 1.00 69.56 N

ANISOU 6259 N ASP F 455 8140 11002 7287 2108 -2939 -971 N

ATOM 6260 CA ASP F 455 45.062 -8.311 -34.481 1.00 74.25 C

ANISOU 6260 CA ASP F 455 8389 11882 7940 2136 -3255 -1090 C

ATOM 6261 CB ASP F 455 45.985 -7.824 -35.605 1.00 75.13 C

ANISOU 6261 CB ASP F 455 7842 12386 8318 2063 -3120 -1280 C

ATOM 6262 CG ASP F 455 46.888 -8.925 -36.144 1.00 78.46 C

ANISOU 6262 CG ASP F 455 7952 12945 8915 2492 -3242 -1425 C

ATOM 6263 OD1 ASP F 455 47.431 -9.720 -35.339 1.00 82.36 O

ANISOU 6263 OD1 ASP F 455 8541 13377 9374 2866 -3625 -1440 O

ATOM 6264 OD2 ASP F 455 47.073 -8.983 -37.376 1.00 77.63 O

ANISOU 6264 OD2 ASP F 455 7515 13007 8974 2469 -2960 -1531 O

ATOM 6265 C ASP F 455 44.811 -7.167 -33.493 1.00 74.78 C

ANISOU 6265 C ASP F 455 8634 11930 7848 1812 -3331 -1036 C

ATOM 6266 O ASP F 455 45.644 -6.915 -32.603 1.00 78.03 O

ANISOU 6266 O ASP F 455 8955 12477 8215 1872 -3689 -1103 O

ATOM 6267 N ASN F 456 43.670 -6.484 -33.647 1.00 72.42 N

ANISOU 6267 N ASN F 456 8584 11465 7468 1486 -3010 -931 N

ATOM 6268 CA ASN F 456 43.375 -5.246 -32.898 1.00 72.87 C

ANISOU 6268 CA ASN F 456 8779 11502 7406 1147 -3004 -908 C

ATOM 6269 CB ASN F 456 43.194 -5.502 -31.383 1.00 74.89 C

ANISOU 6269 CB ASN F 456 9517 11553 7382 1230 -3287 -830 C ATOM 6270 CG ASN F 456 41.742 -5.352 -30.921 1.00 73.35 C ANISOU 6270 CG ASN F 456 9857 11028 6986 1044 -3027 -684 C ATOM 6271 OD1 ASN F 456 40.804 -5.294 -31.734 1.00 71.27 O ANISOU 6271 OD1 ASN F 456 9614 10661 6803 923 -2671 -632 O ATOM 6272 ND2 ASN F 456 41.555 -5.287 -29.604 1.00 75.14 N ANISOU 6272 ND2 ASN F 456 10508 11099 6942 1020 -3208 -632 N ATOM 6273 C ASN F 456 44.415 -4.143 -33.156 1.00 74.75 C ANISOU 6273 C ASN F 456 8515 12082 7807 933 -3067 -1065 C ATOM 6274 O ASN F 456 45.187 -3.760 -32.261 1.00 77.82 O ANISOU 6274 O ASN F 456 8830 12596 8142 912 -3384 -1148 O ATOM 6275 N VAL F 457 44.445 -3.683 -34.408 1.00 73.51 N ANISOU 6275 N VAL F 457 8021 12072 7836 767 -2766 -1110 N ATOM 6276 CA VAL F 457 45.134 -2.453 -34.786 1.00 74.40 C ANISOU 6276 CA VAL F 457 7745 12439 8083 443 -2695 -1225 C ATOM 6277 CB VAL F 457 45.522 -2.397 -36.298 1.00 73.96 C ANISOU 6277 CB VAL F 457 7258 12607 8237 380 -2410 -1296 C ATOM 6278 CG1 VAL F 457 46.942 -2.910 -36.505 1.00 77.90 C ANISOU 6278 CG1 VAL F 457 7228 13455 8917 586 -2608 -1493 C ATOM 6279 CG2 VAL F 457 44.528 -3.164 -37.166 1.00 71.21 C ANISOU 6279 CG2 VAL F 457 7123 12070 7862 520 -2146 -1181 C ATOM 6280 C VAL F 457 44.230 -1.295 -34.377 1.00 72.20 C ANISOU 6280 C VAL F 457 7797 11953 768.

96. 2535 -1135 C ATOM 6281 O VAL F 457 43.123 -1.523 -33.872 1.00 69.99 O ANISOU 6281 O VAL F 457 7977 11379 7238 134 -2467 -1004 O ATOM 6282 N MSE F 458 44.696 -0.064 -34.577 1.00 73.06 N ANISOU 6282 N MSE F 458 7679 12203 7878 -244 -2463 -1216 N ATOM 6283 CA MSE F 458 44.062 1.090 -33.940 1.00 72.35 C ANISOU 6283 CA MSE F 458 7904 11914 7672 -546 -2395 -1172 C ATOM 6284 CB MSE F 458 44.941 2.335 -34.025 1.00 74.88 C ANISOU 6284 CB MSE F 458 7928 12422 8101 -907 -2406 -1306 C ATOM 6285 CG MSE F 458 44.687 3.283 -32.866 1.00 77.18 C ANISOU 6285 CG MSE F 458 8543 12541 8241 -1133 -2523 -1331 C ATOM 6286 SE MSE F 458 44.951 5.167 -33.288 0.90 80.31 SE ANISOU 6286 SE MSE F 458 8839 12926 8747 -1693 -2306 -1407 SE ATOM 6287 CE MSE F 458 45.046 5.835 -31.442 1.00 81.22 C ANISOU 6287 CE MSE F 458 9312 12907 8640 -1838 -2642 -1526 C ATOM 6288 C MSE F 458 42.672 1.407 -34.465 1.00 66.67 C ANISOU 6288 C MSE F 458 7502 10919 6910 -636 -2053 -1019 C ATOM 6289 O MSE F 458 42.496 1.655 -35.655 1.00 65.37 O ANISOU 6289 O MSE F 458 7177 10798 6862 -727 -1796 -981 O ATOM 6290 N GLY F 459 41.699 1.395 -33.554 1.00 63.85 N ANISOU 6290 N GLY F 459 7594 10290 6378 -606 -2058 -941 N ATOM 6291 CA GLY F 459 40.324 1.802 -33.851 1.00 58.57 C ANISOU 6291 CA GLY F 459 7217 9360 5679 -691 -1761 -826 C ATOM 6292 C GLY F 459 39.477 0.783 -34.594 1.00 54.89 C ANISOU 6292 C GLY F 459 6812 8810 5236 -479 -1592 -722 C ATOM 6293 O GLY F 459 38.386 1.107 -35.066 1.00 52.95 O ANISOU 6293 O GLY F 459 6711 8400 5008 -543 -1352 -643 O ATOM 6294 N AMSE F 460 39.968 -0.449 -34.693 0.50 54.86 N ANISOU 6294 N AMSE F 460 6699 8908 5236 -220 -1732 -735 N ATOM 6295 N BMSE F 460 39.971 -0.452 -34.680 0.50 54.79 N ANISOU 6295 N BMSE F 460 6693 8900 5227 -219 -1735 -736 N ATOM 6296 CA AMSE F 460 39.261 -1.491 -35.431 0.50 51.87 C ANISOU 6296 CA AMSE F 460 6376 8449 4883 -31 -1585 -662 C ATOM 6297 CA BMSE F 460 39.302 -1.517 -35.430 0.50 51.83 C ANISOU 6297 CA BMSE F 460 6363 8450 4879 -25 -1593 -665 C ATOM 6298 CB AMSE F 460 40.169 -2.121 -36.484 0.50 52.65 C ANISOU 6298 CB AMSE F 460 6093 8789 5123 111 -1605 -728 C ATOM 6299 CB BMSE F 460 40.281 -2.170 -36.413 0.50 52.63 C ANISOU 6299 CB BMSE F 460 6078 8800 5119 127 -1634 -737 C ATOM 6300 CG AMSE F 460 40.769 -1.118 -37.435 0.50 52.90 C ANISOU 6300 CG AMSE F 460 5781 9031 5286 -116 -1474 -781 C ATOM 6301 CG BMSE F 460 40.942 -1.184 -37.354 0.50 52.67 C ANISOU 6301 CG BMSE F 460 5723 9028 5261 -97 -1512 -797 C ATOM 6302 SE AMSE F 460 40.983 -1.865 -39.199 0.45 52.53 SE ANISOU 6302 SE AMSE F 460 5430 9166 536.

3. 1264 -808 SE ATOM 6303 SE BMSE F 460 39.627 -0.349 -38.511 0.45 48.23 SE ANISOU 6303 SE BMSE F 460 5294 8313 4718 -315 -1143 -673 SE ATOM 6304 CE AMSE F 460 42.271 -0.575 -39.921 0.50 54.18 C ANISOU 6304 CE AMSE F 460 5186 9698 5701 -319 -1174 -914 C ATOM 6305 CE BMSE F 460 40.149 1.530 -38.358 0.50 49.90 C ANISOU 6305 CE BMSE F 460 5422 8568 4968 -714 -1105 -700 C ATOM 6306 C AMSE F 460 38.707 -2.567 -34.517 0.50 51.44 C ANISOU 6306 C AMSE F 460 6684 8191 4671 169 -1681 -606 C ATOM 6307 C BMSE F 460 38.711 -2.576 -34.510 0.50 51.37 C ANISOU 6307 C BMSE F 460 6676 8181 4661 171 -1683 -606 C ATOM 6308 O AMSE F 460 39.431 -3.139 -33.701 0.50 54.01 O ANISOU 6308 O AMSE F 460 7068 8548 4908 330 -1952 -636 O ATOM 6309 O BMSE F 460 39.417 -3.146 -33.677 0.50 53.95 O ANISOU 6309 O BMSE F 460 7068 8534 4895 330 -1953 -635 O ATOM 6310 N VAL F 461 37.413 -2.830 -34.656 1.00 48.69 N ANISOU 6310 N VAL F 461 6584 7631 4285 151 -1461 -525 N ATOM 6311 CA VAL F 461 36.770 -3.939 -33.955 1.00 47.45 C ANISOU 6311 CA VAL F 461 6786 7259 3984 298 -1478 -464 C ATOM 6312 CB VAL F 461 35.734 -3.470 -32.897 1.00 47.00 C ANISOU 6312 CB VAL F 461 7111 6980 3768 144 -1360 -424 C ATOM 6313 CG1 VAL F 461 36.434 -2.715 -31.786 1.00 49.19 C ANISOU 6313 CG1 VAL F 461 7483 7296 391.

62. 1566 -471 C ATOM 6314 CG2 VAL F 461 34.645 -2.627 -33.519 1.00 44.93 C ANISOU 6314 CG2 VAL F 461 6793 6661 3616 -36 -1068 -416 C ATOM 6315 C VAL F 461 36.194 -4.970 -34.930 1.00 45.12 C ANISOU 6315 C VAL F 461 6467 6905 3770 421 -1327 -434 C ATOM 6316 O VAL F 461 35.935 -4.679 -36.100 1.00 43.35 O ANISOU 6316 O VAL F 461 6011 6774 3686 357 -1162 -447 O ATOM 6317 N GLY F 462 36.044 -6.197 -34.453 1.00 45.10 N ANISOU 6317 N GLY F 462 6732 6740 3664 596 -1399 -395 N ATOM 6318 CA GLY F 462 35.452 -7.240 -35.259 1.00 42.67 C ANISOU 6318 CA GLY F 462 6463 6335 3417 690 -1260 -382 C ATOM 6319 C GLY F 462 33.953 -7.209 -35.132 1.00 40.00 C ANISOU 6319 C GLY F 462 6361 5797 3042 512 -999 -335 C ATOM 6320 O GLY F 462 33.413 -6.646 -34.174 1.00 40.52 O ANISOU 6320 O GLY F 462 6646 5756 2995 370 -939 -306 O ATOM 6321 N VAL F 463 33.287 -7.800 -36.113 1.00 37.67 N ANISOU 6321 N VAL F 463 6002 5468 2845 514 -838 -350 N ATOM 6322 CA VAL F 463 31.848 -8.005 -36.073 1.00 35.82 C ANISOU 6322 CA VAL F 463 5947 5057 2604 360 -600 -333 C ATOM 6323 CB VAL F 463 31.095 -7.040 -37.020 1.00 33.67 C ANISOU 6323 CB VAL F 463 5405 4907 2481 210 -430 -364 C ATOM 6324 CG1 VAL F 463 31.567 -7.173 -38.489 1.00 32.45 C ANISOU 6324 CG1 VAL F 463 4944 4937 2447 292 -457 -406 C ATOM 6325 CG2 VAL F 463 29.608 -7.232 -36.898 1.00 33.01 C ANISOU 6325 CG2 VAL F 463 5453 4672 241.

63. 204 -375 C ATOM 6326 C VAL F 463 31.552 -9.483 -36.370 1.00 36.17 C ANISOU 6326 C VAL F 463 6172 4936 2636 457 -567 -337 C ATOM 6327 O VAL F 463 32.101 -10.045 -37.313 1.00 36.03 O ANISOU 6327 O VAL F 463 5987 5003 2702 603 -633 -384 O ATOM 6328 N LEU F 464 30.720 -10.110 -35.536 1.00 36.36 N ANISOU 6328 N LEU F 464 6560 4711 2543 365 -452 -297 N ATOM 6329 CA LEU F 464 30.401 -11.533 -35.679 1.00 37.09 C ANISOU 6329 CA LEU F 464 6903 4585 2604 418 -409 -295 C ATOM 6330 CB LEU F 464 30.195 -12.174 -34.286 1.00 39.07 C ANISOU 6330 CB LEU F 464 7666 4549 2628 385 -405 -204 C ATOM 6331 CG LEU F 464 31.419 -12.196 -33.354 1.00 40.94 C ANISOU 6331 CG LEU F 464 8086 4773 2696 599 -705 -130 C ATOM 6332 CD1 LEU F 464 31.091 -12.743 -31.939 1.00 43.14 C ANISOU 6332 CD1 LEU F 464 8942 4755 2695 535 -688 -20 C ATOM 6333 CD2 LEU F 464 32.590 -12.974 -33.978 1.00 41.49 C

ANISOU 6333 CD2 LEU F 464 8040 4887 2837 924 -961 -154

ATOM 6334 C LEU F 464 29.185 -11.752 -36.603 1.00 35.79 C ANISOU 6334 C LEU F 464 6614 4407 2578 242 -171 -368 C ATOM 6335 O LEU F 464 28.472 -10.801 -36.896 1.00 33.02 O ANISOU 6335 O LEU F 464 6037 4188 232.

87. 41 -402 O ATOM 6336 N PRO F 465 28.971 -12.999 -37.096 1.00 37.43 N ANISOU 6336 N PRO F 465 6964 4455 2802 278 -137 -405 N ATOM 6337 CA PRO F 465 27.800 -13.306 -37.943 1.00 37.58 C ANISOU 6337 CA PRO F 465 6875 4460 2944 8.

62. 496 C ATOM 6338 CB PRO F 465 27.950 -14.814 -38.211 1.00 39.80 C ANISOU 6338 CB PRO F 465 7426 4504 3193 17.

38. 526 C ATOM 6339 CG PRO F 465 29.420 -15.040 -38.140 1.00 39.49 C ANISOU 6339 CG PRO F 465 7412 4494 3099 501 -217 -486 C ATOM 6340 CD PRO F 465 29.850 -14.180 -36.969 1.00 39.01 C ANISOU 6340 CD PRO F 465 7417 4482 2924 517 -307 -380 C ATOM 6341 C PRO F 465 26.410 -12.985 -37.360 1.00 38.58 C ANISOU 6341 C PRO F 465 7067 4510 3081 -204 314 -511 C ATOM 6342 O PRO F 465 25.432 -12.960 -38.117 1.00 38.80 O ANISOU 6342 O PRO F 465 6890 4606 3248 -359 449 -608 O ATOM 6343 N ASP F 466 26.316 -12.749 -36.047 1.00 39.71 N ANISOU 6343 N ASP F 466 7482 4529 3078 -278 375 -433 N ATOM 6344 CA ASP F 466 25.076 -12.246 -35.431 1.00 39.99 C ANISOU 6344 CA ASP F 466 7530 4535 3128 -543 642 -469 C ATOM 6345 CB ASP F 466 24.733 -13.040 -34.157 1.00 42.38 C ANISOU 6345 CB ASP F 466 8343 4540 3221 -688 795 -405 C ATOM 6346 CG ASP F 466 25.745 -12.838 -33.026 1.00 43.25 C ANISOU 6346 CG ASP F 466 8774 4573 3086 -539 618 -276 C ATOM 6347 OD1 ASP F 466 26.686 -12.035 -33.161 1.00 40.47 O ANISOU 6347 OD1 ASP F 466 8215 4411 2751 -348 390 -255 O ATOM 6348 OD2 ASP F 466 25.589 -13.493 -31.976 1.00 46.27 O ANISOU 6348 OD2 ASP F 466 9636 4699 3245 -632 706 -198 O ATOM 6349 C ASP F 466 25.070 -10.709 -35.183 1.00 38.76 C ANISOU 6349 C ASP F 466 7126 4585 3017 -543 641 -473 C ATOM 6350 O ASP F 466 24.221 -10.195 -34.450 1.00 39.42 O ANISOU 6350 O ASP F 466 7256 4637 3087 -715 852 -505 O ATOM 6351 N MSE F 467 26.016 -10.007 -35.819 1.00 37.33 N ANISOU 6351 N MSE F 467 6690 4601 2894 -358 423 -453 N ATOM 6352 CA MSE F 467 26.170 -8.534 -35.809 1.00 35.96 C ANISOU 6352 CA MSE F 467 6277 4607 2779 -345 387 -455 C ATOM 6353 CB MSE F 467 24.899 -7.811 -36.252 1.00 35.73 C ANISOU 6353 CB MSE F 467 5992 4658 2926 -482 577 -541 C ATOM 6354 CG MSE F 467 24.737 -7.701 -37.761 1.00 34.64 C ANISOU 6354 CG MSE F 467 5513 4688 2961 -427 503 -584 C ATOM 6355 SE MSE F 467 26.345 -7.142 -38.729 0.90 36.20 SE ANISOU 6355 SE MSE F 467 5518 5088 3149 -218 224 -515 SE ATOM 6356 CE MSE F 467 26.525 -5.301 -38.059 1.00 32.31 C ANISOU 6356 CE MSE F 467 4958 4657 2664 -246 217 -475 C ATOM 6357 C MSE F 467 26.703 -7.992 -34.476 1.00 37.22 C ANISOU 6357 C MSE F 467 6683 4702 2756 -343 341 -397 C ATOM 6358 O MSE F 467 26.687 -6.785 -34.186 1.00 35.87 O ANISOU 6358 O MSE F 467 6406 4617 2608 -377 355 -413 O ATOM 6359 N THR F 468 27.215 -8.919 -33.687 1.00 39.05 N ANISOU 6359 N THR F 468 7274 4768 2795 -291 262 -331 N ATOM 6360 CA THR F 468 27.716 -8.634 -32.358 1.00 40.94 C ANISOU 6360 CA THR F 468 7827 4923 2805 -287 187 -272 C ATOM 6361 CB THR F 468 27.372 -9.857 -31.476 1.00 43.19 C ANISOU 6361 CB THR F 468 8602 4931 2878 -353 280 -210 C ATOM 6362 OG1 THR F 468 26.274 -9.513 -30.624 1.00 44.16 O ANISOU 6362 OG1 THR F 468 8907 4957 2915 -594 586 -247 O ATOM 6363 CG2 THR F 468 28.546 -10.408 -30.685 1.00 46.31 C ANISOU 6363 CG2 THR F 468 9341 5221 3032 -165 -11 -103 C ATOM 6364 C THR F 468 29.201 -8.251 -32.487 1.00 40.62 C ANISOU 6364 C THR F 468 7654 5035 2745 -81 -147 -239 C ATOM 6365 O THR F 468 29.894 -8.776 -33.364 1.00 40.74 O ANISOU 6365 O THR F 468 7490 5133 285.

84. 302 -238 O ATOM 6366 N PRO F 469 29.679 -7.295 -31.671 1.00 41.09 N ANISOU 6366 N PRO F 469 7766 5150 2694 -102 -242 -236 N ATOM 6367 CA PRO F 469 31.083 -6.882 -31.768 1.00 41.16 C ANISOU 6367 CA PRO F 469 7605 5330 270.

54. 555 -230 C ATOM 6368 CB PRO F 469 31.077 -5.503 -31.123 1.00 40.81 C ANISOU 6368 CB PRO F 469 7543 5347 2614 -81 -534 -273 C ATOM 6369 CG PRO F 469 30.006 -5.598 -30.079 1.00 42.91 C ANISOU 6369 CG PRO F 469 8187 5411 2707 -237 -295 -271 C ATOM 6370 CD PRO F 469 28.964 -6.555 -30.615 1.00 42.09 C ANISOU 6370 CD PRO F 469 8108 5193 2693 -283 -58 -262 C ATOM 6371 C PRO F 469 32.038 -7.820 -30.998 1.00 43.78 C ANISOU 6371 C PRO F 469 8232 5571 2832 239 -831 -163 C ATOM 6372 O PRO F 469 31.609 -8.515 -30.066 1.00 45.55 O ANISOU 6372 O PRO F 469 8901 5569 2839 206 -778 -99 O ATOM 6373 N SER F 470 33.313 -7.825 -31.394 1.00 43.90 N ANISOU 6373 N SER F 470 8000 5762 2916 433 -1119 -181 N ATOM 6374 CA SER F 470 34.346 -8.639 -30.751 1.00 46.64 C ANISOU 6374 CA SER F 470 8551 6062 3110 671 -1446 -135 C ATOM 6375 CB SER F 470 34.315 -10.073 -31.297 1.00 47.59 C ANISOU 6375 CB SER F 470 8779 6031 3271 863 -1454 -97 C ATOM 6376 OG SER F 470 35.473 -10.807 -30.918 1.00 49.69 O ANISOU 6376 OG SER F 470 9140 6283 3454 1168 -1812 -71 O ATOM 6377 C SER F 470 35.752 -8.045 -30.913 1.00 47.35 C ANISOU 6377 C SER F 470 8278 6429 3286 805 -1756 -203 C ATOM 6378 O SER F 470 36.105 -7.528 -31.963 1.00 45.73 O ANISOU 6378 O SER F 470 7626 6442 3306 790 -1714 -278 O ATOM 6379 N THR F 471 36.553 -8.143 -29.862 1.00 50.52 N ANISOU 6379 N THR F 471 8881 6821 3494 925 -2070 -182 N ATOM 6380 CA THR F 471 37.935 -7.704 -29.919 1.00 52.23 C ANISOU 6380 CA THR F 471 8738 7311 3795 1058 -2399 -268 C ATOM 6381 CB THR F 471 38.370 -7.063 -28.571 1.00 54.64 C ANISOU 6381 CB THR F 471 9275 7631 3857 989 -2649 -274 C ATOM 6382 OG1 THR F 471 38.127 -7.985 -27.503 1.00 57.14 O ANISOU 6382 OG1 THR F 471 10164 7680 3867 1111 -2776 -156 O ATOM 6383 CG2 THR F 471 37.604 -5.758 -28.297 1.00 51.68 C ANISOU 6383 CG2 THR F 471 8940 7250 3448 642 -2391 -311 C ATOM 6384 C THR F 471 38.872 -8.866 -30.315 1.00 54.76 C ANISOU 6384 C THR F 471 8937 7670 4198 1425 -2659 -278 C ATOM 6385 O THR F 471 40.081 -8.673 -30.459 1.00 56.74 O ANISOU 6385 O THR F 471 8822 8174 4560 1580 -2936 -374 O ATOM 6386 N GLU F 472 38.310 -10.061 -30.502 1.00 55.20 N ANISOU 6386 N GLU F 472 9286 7473 4215 1560 -2559 -198 N ATOM 6387 CA GLU F 472 39.103 -11.273 -30.764 1.00 58.61 C ANISOU 6387 CA GLU F 472 9708 7861 4701 1944 -2804 -203 C ATOM 6388 CB GLU F 472 38.944 -12.273 -29.615 1.00 61.64 C ANISOU 6388 CB GLU F 472 10735 7900 4787 2108 -2991 -57 C ATOM 6389 CG GLU F 472 39.602 -11.834 -28.294 1.00 66.05 C ANISOU 6389 CG GLU F 472 11497 8504 5096 2156 -3355 -23 C ATOM 6390 CD GLU F 472 39.044 -12.577 -27.088 1.00 68.99 C ANISOU 6390 CD GLU F 472 12632 8493 5089 2173 -3414 155 C ATOM 6391 OE1 GLU F 472 39.536 -12.355 -25.958 1.00 74.88 O ANISOU 6391 OE1 GLU F 472 13642 9238 5571 2229 -3734 199 O ATOM 6392 OE2 GLU F 472 38.110 -13.393 -27.270 1.00 70.96 O ANISOU 6392 OE2 GLU F 472 13234 8438 5289 2110 -3138 248 O ATOM 6393 C GLU F 472 38.814 -11.965 -32.106 1.00 56.75 C ANISOU 6393 C GLU F 472 9268 7606 4689 2022 -2575 -253 C ATOM 6394 O GLU F 472 39.740 -12.338 -32.826 0.50 57.96 O ANISOU 6394 O GLU F 472 9067 7930 5026 2279 -2713 -356 O ATOM 6395 N AMSE F 473 37.538 -12.106 -32.442 0.50 54.05 N ANISOU 6395 N AMSE F 473 9129 7077 4333 1792 -2225 -203 N ATOM 6396 N BMSE F 473 37.527 -12.152 -32.413 0.50 54.67 N ANISOU 6396 N BMSE F 473 9227 7140 4403 1798 -2228 -198 N ATOM 6397 CA AMSE F 473 37.154 -12.767 -33.686 0.50 52.38 C

ANISOU 6397 CA AMSE F 473 8771 6831 4299 1830 -2013 -259 C

ATOM 6398 CA BMSE F 473 37.061 -12.837 -33.638 0.50 53.57 C

ANISOU 6398 CA BMSE F 473 8970 6950 4436 1823 -2000 -249 C

ATOM 6399 CB AMSE F 473 36.349 -14.042 -33.398 0.50 53.56 C

ANISOU 6399 CB AMSE F 473 9451 6579 4320 1866 -1917 -167 C

ATOM 6400 CB BMSE F 473 36.126 -14.020 -33.278 0.50 54.56 C

ANISOU 6400 CB BMSE F 473 9648 6665 4417 1812 -1876 -149 C

ATOM 6401 CG AMSE F 473 37.019 -15.032 -32.430 0.50 57.16 C

ANISOU 6401 CG AMSE F 473 10331 6794 4594 2182 -2241 -77 C

ATOM 6402 CG BMSE F 473 36.799 -15.413 -33.076 0.50 59.08 C

ANISOU 6402 CG BMSE F 473 10512 7000 4934 2193 -2125 -118 C

ATOM 6403 SE AMSE F 473 38.682 -15.802 -33.103 0.45 58.91 SE

ANISOU 6403 SE AMSE F 473 10192 7173 5018 2733 -2611 -206 SE

ATOM 6404 SE BMSE F 473 35.701 -16.903 -32.302 0.45 62.74 SE

ANISOU 6404 SE BMSE F 473 11838 6858 5142 2138 -1994 50 SE

ATOM 6405 CE AMSE F 473 37.985 -17.029 -34.440 0.50 58.03 C

ANISOU 6405 CE AMSE F 473 10158 6829 5063 2774 -2311 -279 C

ATOM 6406 CE BMSE F 473 34.039 -16.732 -33.323 0.50 58.44 C

ANISOU 6406 CE BMSE F 473 11168 6293 4743 1680 -1460 -22 C

ATOM 6407 C AMSE F 473 36.353 -11.826 -34.583 0.50 48.62 C

ANISOU 6407 C AMSE F 473 7996 6515 3962 1519 -1691 -310 C

ATOM 6408 C BMSE F 473 36.326 -11.854 -34.571 0.50 49.21 C

ANISOU 6408 C BMSE F 473 8085 6580 4033 1518 -1688 -307 C

ATOM 6409 O AMSE F 473 35.756 -10.854 -34.118 0.50 46.99 O

ANISOU 6409 O AMSE F 473 7827 6334 3694 1260 -1572 -275 O

ATOM 6410 O BMSE F 473 35.750 -10.866 -34.112 0.50 47.60 O

ANISOU 6410 O BMSE F 473 7908 6407 3769 1261 -1572 -274 O

ATOM 6411 N SER F 474 36.355 -12.116 -35.876 1.00 47.59 N

ANISOU 6411 N SER F 474 7586 6486 4008 1564 -1563 -398 N

ATOM 6412 CA SER F 474 35.584 -11.319 -36.852 1.00 44.33 C

ANISOU 6412 CA SER F 474 6917 6214 3712 1304 -1290 -437 C

ATOM 6413 CB SER F 474 36.392 -10.097 -37.301 1.00 43.46 C

ANISOU 6413 CB SER F 474 6360 6443 3709 1243 -1335 -499 C

ATOM 6414 OG SER F 474 35.624 -9.222 -38.089 1.00 39.78 O

ANISOU 6414 OG SER F 474 5726 6072 3317 997 -1104 -503 O

ATOM 6415 C SER F 474 35.225 -12.160 -38.070 1.00 43.77 C

ANISOU 6415 C SER F 474 6781 6105 3745 1359 -1143 -510 C

ATOM 6416 O SER F 474 35.885 -13.164 -38.345 1.00 45.97 O

ANISOU 6416 O SER F 474 7084 6329 4052 1623 -1256 -566 O

ATOM 6417 N MSE F 475 34.196 -11.754 -38.806 1.00 41.25 N

ANISOU 6417 N MSE F 475 6380 5813 3480 1127 -909 -523 N

ATOM 6418 CA MSE F 475 34.003 -12.291 -40.149 1.00 40.97 C

ANISOU 6418 CA MSE F 475 6197 5831 3539 1157 -792 -619 C

ATOM 6419 CB MSE F 475 32.693 -11.806 -40.771 1.00 38.57 C

ANISOU 6419 CB MSE F 475 5849 5536 3270 888 -576 -618 C

ATOM 6420 CG MSE F 475 31.457 -12.502 -40.205 1.00 38.53 C

ANISOU 6420 CG MSE F 475 6187 5241 3212 749 -456 -585 C

ATOM 6421 SE MSE F 475 29.784 -11.880 -40.999 0.90 37.77 SE

ANISOU 6421 SE MSE F 475 5943 5203 3204 437 -222 -623 SE

ATOM 6422 CE MSE F 475 29.784 -10.021 -40.369 1.00 34.50 C

ANISOU 6422 CE MSE F 475 5347 4962 2799 318 -223 -536 C

ATOM 6423 C MSE F 475 35.210 -11.913 -41.018 1.00 41.26 C

ANISOU 6423 C MSE F 475 5836 6174 3668 1296 -861 -711 C

ATOM 6424 O MSE F 475 35.709 -10.786 -40.947 1.00 40.52 O

ANISOU 6424 O MSE F 475 5499 6296 3600 1209 -892 -694 O

ATOM 6425 N ARG F 476 35.662 -12.871 -41.825 1.00 42.54 N

ANISOU 6425 N ARG F 476 5947 6338 3877 1494 -862 -821 N

ATOM 6426 CA ARG F 476 36.908 -12.783 -42.592 1.00 43.25 C

ANISOU 6426 CA ARG F 476 5676 6704 4054 1670 -906 -942 C

ATOM 6427 CB ARG F 476 37.047 -14.035 -43.462 1.00 44.93 C

ANISOU 6427 CB ARG F 476 5941 6831 4299 1877 -855 -1078 C

ATOM 6428 CG ARG F 476 38.089 -13.966 -44.568 1.00 47.16 C

ANISOU 6428 CG ARG F 476 5839 7416 4664 2010 -797 -1241 C

ATOM 6429 CD ARG F 476 38.138 -15.267 -45.379 1.00 48.80 C

ANISOU 6429 CD ARG F 476 6156 7498 4889 2224 -733 -1397 C ATOM 6430 NE ARG F 476 36.829 -15.772 -45.815 1.00 48.30 N ANISOU 6430 NE ARG F 476 6394 7206 4752 2046 -602 -1383 N ATOM 6431 CZ ARG F 476 36.126 -15.297 -46.843 1.00 47.93 C ANISOU 6431 CZ ARG F 476 6261 7289 4660 1803 -431 -1409 C ATOM 6432 NH1 ARG F 476 36.574 -14.273 -47.565 1.00 48.79 N ANISOU 6432 NH1 ARG F 476 6042 7730 4765 1693 -345 -1425 N ATOM 6433 NH2 ARG F 476 34.962 -15.848 -47.154 1.00 46.79 N ANISOU 6433 NH2 ARG F 476 6372 6939 4466 1657 -353 -1419 N ATOM 6434 C ARG F 476 37.030 -11.498 -43.416 1.00 41.10 C ANISOU 6434 C ARG F 476 5060 6740 3817 1453 -777 -953 C ATOM 6435 O ARG F 476 36.182 -11.199 -44.258 1.00 39.12 O ANISOU 6435 O ARG F 476 4810 6511 3545 1266 -612 -945 O ATOM 6436 N GLY F 477 38.082 -10.733 -43.140 1.00 41.43 N ANISOU 6436 N GLY F 477 4825 7009 3906 1471 -870 -969 N ATOM 6437 CA GLY F 477 38.354 -9.486 -43.850 1.00 40.53 C ANISOU 6437 CA GLY F 477 4413 7168 3820 1250 -748 -972 C ATOM 6438 C GLY F 477 37.457 -8.303 -43.526 1.00 37.97 C ANISOU 6438 C GLY F 477 4192 6789 3447 958 -686 -834 C ATOM 6439 O GLY F 477 37.588 -7.235 -44.118 1.00 37.40 O ANISOU 6439 O GLY F 477 3939 6888 3383 765 -584 -814 O ATOM 6440 N ILE F 478 36.549 -8.489 -42.574 1.00 37.64 N ANISOU 6440 N ILE F 478 4456 6494 3350 927 -734 -743 N ATOM 6441 CA ILE F 478 35.552 -7.457 -42.189 1.00 35.63 C ANISOU 6441 CA ILE F 478 4320 6155 3064 685 -661 -635 C ATOM 6442 CB ILE F 478 34.126 -8.080 -42.125 1.00 34.02 C ANISOU 6442 CB ILE F 478 4389 5711 2826 640 -565 -600 C ATOM 6443 CG1 ILE F 478 33.806 -8.827 -43.435 1.00 33.55 C ANISOU 6443 CG1 ILE F 478 4276 5687 2784 683 -466 -676 C ATOM 6444 CD1 ILE F 478 33.521 -7.945 -44.656 1.00 30.29 C ANISOU 6444 CD1 ILE F 478 3677 5452 2378 537 -355 -670 C ATOM 6445 CG2 ILE F 478 33.074 -7.027 -41.766 1.00 33.10 C ANISOU 6445 CG2 ILE F 478 4345 5524 2706 427 -477 -518 C ATOM 6446 C ILE F 478 35.903 -6.782 -40.854 1.00 36.01 C ANISOU 6446 C ILE F 478 4438 6165 3079 636 -794 -583 C ATOM 6447 O ILE F 478 35.986 -7.446 -39.812 1.00 37.11 O ANISOU 6447 O ILE F 478 4791 6153 3155 758 -925 -568 O ATOM 6448 N ARG F 479 36.123 -5.467 -40.889 1.00 35.61 N ANISOU 6448 N ARG F 479 4243 6236 3052 452 -766 -558 N ATOM 6449 CA ARG F 479 36.358 -4.678 -39.648 1.00 35.25 C ANISOU 6449 CA ARG F 479 4285 6146 2962 361 -880 -526 C ATOM 6450 CB ARG F 479 37.771 -4.102 -39.604 1.00 37.00 C ANISOU 6450 CB ARG F 479 4220 6604 3234 340 -1006 -596 C ATOM 6451 CG ARG F 479 38.905 -5.105 -39.660 1.00 39.51 C ANISOU 6451 CG ARG F 479 4354 7064 3594 589 -1165 -694 C ATOM 6452 CD ARG F 479 38.890 -6.113 -38.506 1.00 39.37 C ANISOU 6452 CD ARG F 479 4610 6863 3485 811 -1371 -676 C ATOM 6453 NE ARG F 479 39.992 -7.062 -38.667 1.00 43.02 N ANISOU 6453 NE ARG F 479 4879 7454 4013 1100 -1539 -778 N ATOM 6454 CZ ARG F 479 39.943 -8.180 -39.394 1.00 42.54 C ANISOU 6454 CZ ARG F 479 4821 7349 3992 1310 -1482 -822 C ATOM 6455 NH1 ARG F 479 38.836 -8.535 -40.045 1.00 39.17 N ANISOU 6455 NH1 ARG F 479 4582 6764 3539 1240 -1271 -774 N ATOM 6456 NH2 ARG F 479 41.014 -8.951 -39.460 1.00 44.32 N ANISOU 6456 NH2 ARG F 479 4855 7691 4295 1600 -1648 -933 N ATOM 6457 C ARG F 479 35.379 -3.518 -39.523 1.00 33.52 C ANISOU 6457 C ARG F 479 4176 5824 2735 141 -749 -457 C ATOM 6458 O ARG F 479 34.960 -2.946 -40.533 1.00 33.11 O ANISOU 6458 O ARG F 479 4023 5824 273.

39. 613 -431 O ATOM 6459 N VAL F 480 35.010 -3.170 -38.293 1.00 33.05 N ANISOU 6459 N VAL F 480 4342 5614 260.

83. 794 -431 N ATOM 6460 CA VAL F 480 34.211 -1.973 -38.054 1.00 31.67 C ANISOU 6460 CA VAL F 480 4261 5340 2433 -100 -679 -394 C ATOM 6461 CB VAL F 480 32.975 -2.270 -37.150 1.00 31.19 C ANISOU 6461 CB VAL F 480 4503 5047 2302 -107 -586 -373 C ATOM 6462 CG1 VAL F 480 32.299 -0.976 -36.650 1.00 29.99 C ANISOU 6462 CG1 VAL F 480 4449 4788 2157 -263 -483 -369 C ATOM 6463 CG2 VAL F 480 31.966 -3.168 -37.871 1.00 30.56 C ANISOU 6463 CG2 VAL F 480 4439 4902 2268 -46 -452 -362 C ATOM 6464 C VAL F 480 35.128 -0.915 -37.429 1.00 32.95 C ANISOU 6464 C VAL F 480 4368 5575 2578 -225 -792 -424 C ATOM 6465 O VAL F 480 35.745 -1.151 -36.395 1.00 34.11 O ANISOU 6465 O VAL F 480 4604 5721 2637 -182 -961 -460 O ATOM 6466 N SER F 481 35.233 0.241 -38.068 1.00 33.25 N ANISOU 6466 N SER F 481 4278 5667 2688 -388 -713 -411 N ATOM 6467 CA SER F 481 36.017 1.336 -37.502 1.00 35.24 C ANISOU 6467 CA SER F 481 4499 5958 2933 -559 -797 -452 C ATOM 6468 CB SER F 481 36.437 2.355 -38.572 1.00 35.71 C ANISOU 6468 CB SER F 481 4370 6117 3082 -738 -702 -431 C ATOM 6469 OG SER F 481 37.145 3.457 -37.988 1.00 38.65 O ANISOU 6469 OG SER F 481 4738 6495 3454 -948 -769 -482 O ATOM 6470 C SER F 481 35.306 2.040 -36.341 1.00 35.43 C ANISOU 6470 C SER F 481 4816 5766 2882 -645 -777 -459 C ATOM 6471 O SER F 481 34.117 2.366 -36.409 1.00 34.16 O ANISOU 6471 O SER F 481 4805 5434 2740 -653 -618 -419 O ATOM 6472 N LYS F 482 36.073 2.261 -35.283 1.00 37.40 N ANISOU 6472 N LYS F 482 5126 6040 3045 -702 -948 -528 N ATOM 6473 CA LYS F 482 35.676 3.070 -34.149 1.00 38.68 C ANISOU 6473 CA LYS F 482 5562 6025 3110 -819 -945 -569 C ATOM 6474 CB LYS F 482 36.268 2.482 -32.863 1.00 40.92 C ANISOU 6474 CB LYS F 482 5998 6331 3219 -756 -1171 -627 C ATOM 6475 CG LYS F 482 35.631 1.192 -32.366 1.00 43.46 C ANISOU 6475 CG LYS F 482 6540 6556 3418 -560 -1164 -577 C ATOM 6476 CD LYS F 482 34.408 1.466 -31.467 1.00 47.95 C ANISOU 6476 CD LYS F 482 7475 6881 3862 -619 -984 -579 C ATOM 6477 CE LYS F 482 33.121 1.568 -32.297 1.00 47.40 C ANISOU 6477 CE LYS F 482 7363 6708 3938 -612 -696 -534 C ATOM 6478 NZ LYS F 482 32.024 2.121 -31.458 1.00 48.36 N ANISOU 6478 NZ LYS F 482 7761 6627 3987 -690 -499 -580 N ATOM 6479 C LYS F 482 36.172 4.524 -34.290 1.00 39.57 C ANISOU 6479 C LYS F 482 5613 6135 3288 -1061 -935 -613 C ATOM 6480 O LYS F 482 35.963 5.337 -33.378 1.00 40.79 O ANISOU 6480 O LYS F 482 5995 6137 3367 -1181 -937 -673 O ATOM 6481 N MSE F 483 36.839 4.848 -35.404 1.00 38.62 N ANISOU 6481 N MSE F 483 5216 6167 3290 -1150 -910 -591 N ATOM 6482 CA MSE F 483 37.361 6.208 -35.607 1.00 39.11 C ANISOU 6482 CA MSE F 483 5242 6208 3412 -1419 -881 -623 C ATOM 6483 CB MSE F 483 38.321 6.273 -36.805 1.00 39.75 C ANISOU 6483 CB MSE F 483 4987 6519 3599 -1525 -853 -609 C ATOM 6484 CG MSE F 483 39.626 5.497 -36.598 1.00 41.96 C ANISOU 6484 CG MSE F 483 4958 7098 3887 -1482 -1052 -714 C ATOM 6485 SE MSE F 483 40.539 5.770 -34.876 0.90 50.05 SE ANISOU 6485 SE MSE F 483 6036 8169 4812 -1584 -1372 -884 SE ATOM 6486 CE MSE F 483 41.373 7.511 -35.168 1.00 48.50 C ANISOU 6486 CE MSE F 483 5726 7986 4714 -2058 -1303 -969 C ATOM 6487 C MSE F 483 36.227 7.226 -35.749 1.00 37.49 C ANISOU 6487 C MSE F 483 5289 5719 3238 -1481 -693 -566 C ATOM 6488 O MSE F 483 35.094 6.823 -36.053 1.00 35.28 O ANISOU 6488 O MSE F 483 5099 5332 2975 -1307 -572 -494 O ATOM 6489 OXT MSE F 483 36.389 8.431 -35.532 1.00 37.47 O ANISOU 6489 OXT MSE F 483 5406 5580 3252 -1689 -668 -602 O ATOM 6490 O2G MGT A 1 48.431 21.314 -32.822 1.00 51.34 O ANISOU 6490 O2G MGT A 1 5580 7344 6582 -151 662 268 O ATOM 6491 PG MGT A 1 47.642 21.644 -31.468 1.00 49.83 P ANISOU 6491 PG MGT A 1 5455 6960 6518 -139 518 275 P ATOM 6492 O3G MGT A 1 46.906 20.295 -30.960 1.00 45.91 O ANISOU 6492 O3G MGT A 1 5042 6412 5989 23 408 176 O ATOM 6493 O1G MGT A 1 48.607 22.186 -30.469 1.00 50.23 O

ANISOU 6493 O1G MGT A 1 5363 7007 6715 -196 508 226 O

ATOM 6494 O3B MGT A 1 46.392 22.571 -31.946 1.00 49.90 O

ANISOU 6494 O3B MGT A 1 5618 6851 6491 -212 497 434 O

ATOM 6495 PB MGT A 1 46.500 23.966 -32.785 1.00 50.34 P

ANISOU 6495 PB MGT A 1 5693 6896 6537 -368 593 604 P

ATOM 6496 O2B MGT A 1 46.307 23.569 -34.337 1.00 50.62 O

ANISOU 6496 O2B MGT A 1 5793 7073 6368 -354 675 667 O

ATOM 6497 O1B MGT A 1 47.806 24.652 -32.528 1.00 51.47 O

ANISOU 6497 O1B MGT A 1 5686 7087 6785 -486 681 592 O

ATOM 6498 O3A MGT A 1 45.229 24.838 -32.232 1.00 49.00 O

ANISOU 6498 O3A MGT A 1 5651 6519 6447 -386 490 701 O

ATOM 6499 PA MGT A 1 43.722 24.280 -31.756 1.00 44.78 P

ANISOU 6499 PA MGT A 1 5239 5880 5896 -269 352 675 P

ATOM 6500 O2A MGT A 1 43.564 22.796 -32.345 1.00 45.17 O

ANISOU 6500 O2A MGT A 1 5307 6056 5798 -157 346 583 O

ATOM 6501 O1A MGT A 1 42.713 25.256 -32.229 1.00 46.58 O

ANISOU 6501 O1A MGT A 1 5577 6005 6118 -305 327 828 O

ATOM 6502 O5* MGT A 1 43.626 24.206 -30.136 1.00 42.80 O

ANISOU 6502 O5* MGT A 1 4955 5516 5792 -234 258 568 O

ATOM 6503 C5* MGT A 1 43.771 25.451 -29.389 1.00 38.57 C

ANISOU 6503 C5* MGT A 1 4398 4855 5403 -327 250 603 C

ATOM 6504 C4* MGT A 1 44.860 25.368 -28.297 1.00 34.92 C

ANISOU 6504 C4* MGT A 1 3808 4419 5042 -349 242 478 C

ATOM 6505 O4* MGT A 1 44.641 24.152 -27.533 1.00 33.27 O

ANISOU 6505 O4* MGT A 1 3599 4240 4800 -224 161 362 O

ATOM 6506 C3* MGT A 1 46.295 25.288 -28.821 1.00 34.19 C

ANISOU 6506 C3* MGT A 1 3578 4475 4937 -411 343 453 C

ATOM 6507 O3* MGT A 1 47.120 26.048 -27.945 1.00 35.75 O

ANISOU 6507 O3* MGT A 1 3669 4640 5274 -506 342 399 O

ATOM 6508 C2* MGT A 1 46.671 23.831 -28.682 1.00 33.94 C

ANISOU 6508 C2* MGT A 1 3496 4568 4833 -279 318 333 C

ATOM 6509 O2* MGT A 1 48.079 23.737 -28.438 1.00 37.14 O

ANISOU 6509 O2* MGT A 1 3729 5093 5289 -308 364 248 O

ATOM 6510 C1* MGT A 1 45.936 23.471 -27.403 1.00 30.89 C

ANISOU 6510 C1* MGT A 1 3166 4076 4495 -198 191 266 C

ATOM 6511 N9 MGT A 1 45.522 22.046 -27.080 1.00 29.66 N

ANISOU 6511 N9 MGT A 1 3059 3943 4269 -51 124 187 N

ATOM 6512 C8 MGT A 1 44.505 21.434 -27.715 1.00 27.88 C

ANISOU 6512 C8 MGT A 1 2948 3695 3949 8 112 221 C

ATOM 6513 N7 MGT A 1 44.411 20.228 -27.155 1.00 27.01 N

ANISOU 6513 N7 MGT A 1 2858 3589 3815 120 53 134 N

ATOM 6514 CM7 MGT A 1 43.375 19.249 -27.561 1.00 25.30 C

ANISOU 6514 CM7 MGT A 1 2758 3341 3512 194 23 127 C

ATOM 6515 C5 MGT A 1 45.336 20.071 -26.191 1.00 27.24 C

ANISOU 6515 C5 MGT A 1 2792 3648 3910 147 21 59 C

ATOM 6516 C4 MGT A 1 46.053 21.249 -26.149 1.00 27.82 C

ANISOU 6516 C4 MGT A 1 2769 3743 4059 34 64 84 C

ATOM 6517 N3 MGT A 1 47.061 21.426 -25.271 1.00 27.51 N

ANISOU 6517 N3 MGT A 1 2607 3751 4096 24 36 11 N

ATOM 6518 C2 MGT A 1 47.423 20.471 -24.405 1.00 28.78 C

ANISOU 6518 C2 MGT A 1 2738 3945 4254 139 -41 -75 C

ATOM 6519 N2 MGT A 1 48.443 20.701 -23.575 1.00 29.71 N

ANISOU 6519 N2 MGT A 1 2722 4129 4439 129 -80 -146 N

ATOM 6520 N1 MGT A 1 46.712 19.246 -24.380 1.00 27.51 N

ANISOU 6520 N1 MGT A 1 2690 3743 4019 264 -84 -86 N

ATOM 6521 C6 MGT A 1 45.678 19.057 -25.295 1.00 26.68 C

ANISOU 6521 C6 MGT A 1 2705 3587 3846 258 -48 -26 C

ATOM 6522 O6 MGT A 1 45.070 17.997 -25.311 1.00 27.25 O

ANISOU 6522 O6 MGT A 1 2870 3620 3863 348 -80 -46 O

ATOM 6523 O2G MGT B 1 8.911 7.379 -30.815 1.00 52.96 O

ANISOU 6523 O2G MGT B 1 6523 7405 6194 480 -1101 341 O

ATOM 6524 PG MGT B 1 8.686 7.207 -29.221 1.00 49.79 P

ANISOU 6524 PG MGT B 1 5992 6928 5999 504 -1012 247 P

ATOM 6525 O3G MGT B 1 10.111 6.727 -28.566 1.00 47.34 O

ANISOU 6525 O3G MGT B 1 5764 6484 5738 339 -851 158 O

ATOM 6526 O1G MGT B 1 8.184 8.475 -28.631 1.00 50.87 O

ANISOU 6526 O1G MGT B 1 6159 6948 6223 702 -1015 339 O

ATOM 6527 O3B MGT B 1 7.735 5.911 -29.048 1.00 49.75 O

ANISOU 6527 O3B MGT B 1 5755 7120 6027 437 -1075 126 O

ATOM 6528 PB MGT B 1 6.305 5.749 -29.792 1.00 51.97 P

ANISOU 6528 PB MGT B 1 5864 7633 6251 512 -1261 156 P

ATOM 6529 O2B MGT B 1 6.621 5.123 -31.256 1.00 52.42 O

ANISOU 6529 O2B MGT B 1 6011 7805 6099 381 -1353 144 O

ATOM 6530 O1B MGT B 1 5.596 7.053 -29.893 1.00 53.94 O

ANISOU 6530 O1B MGT B 1 6111 7869 6514 750 -1339 301 O

ATOM 6531 O3A MGT B 1 5.465 4.683 -28.886 1.00 50.43 O

ANISOU 6531 O3A MGT B 1 5422 7553 6185 435 -1246 27 O

ATOM 6532 PA MGT B 1 5.986 3.318 -28.093 1.00 45.51 P

ANISOU 6532 PA MGT B 1 4771 6888 5634 227 -1122 -129 P

ATOM 6533 O2A MGT B 1 7.298 2.764 -28.782 1.00 43.17 O

ANISOU 6533 O2A MGT B 1 4672 6508 522.

84. 1068 -175 O

ATOM 6534 O1A MGT B 1 4.876 2.329 -28.139 1.00 43.87 O

ANISOU 6534 O1A MGT B 1 4348 6870 5450 131 -1206 -207 O

ATOM 6535 O5* MGT B 1 6.408 3.771 -26.568 1.00 42.04 O

ANISOU 6535 O5* MGT B 1 4356 6273 5345 294 -960 -138 O

ATOM 6536 C5* MGT B 1 5.376 4.024 -25.569 1.00 40.75 C

ANISOU 6536 C5* MGT B 1 4018 6158 5306 403 -935 -137 C

ATOM 6537 C4* MGT B 1 5.580 5.362 -24.810 1.00 38.17 C

ANISOU 6537 C4* MGT B 1 3791 5670 5043 591 -859 -67 C

ATOM 6538 O4* MGT B 1 6.866 5.317 -24.120 1.00 33.12 O

ANISOU 6538 O4* MGT B 1 3324 4841 4420 503 -736 -111 O

ATOM 6539 C3* MGT B 1 5.606 6.610 -25.719 1.00 38.56 C

ANISOU 6539 C3* MGT B 1 3962 5672 5018 750 -947 64 C

ATOM 6540 O3* MGT B 1 4.951 7.705 -25.060 1.00 39.09 O

ANISOU 6540 O3* MGT B 1 4007 5678 5169 978 -922 122 O

ATOM 6541 C2* MGT B 1 7.108 6.900 -25.892 1.00 36.08 C

ANISOU 6541 C2* MGT B 1 3897 5166 4648 655 -875 76 C

ATOM 6542 O2* MGT B 1 7.314 8.312 -26.089 1.00 40.76 O

ANISOU 6542 O2* MGT B 1 4655 5608 5223 807 -882 193 O

ATOM 6543 C1* MGT B 1 7.650 6.495 -24.540 1.00 30.98 C

ANISOU 6543 C1* MGT B 1 3257 4415 4100 578 -738 -22 C

ATOM 6544 N9 MGT B 1 9.078 6.082 -24.348 1.00 28.02 N

ANISOU 6544 N9 MGT B 1 3017 3924 3707 418 -654 -71 N

ATOM 6545 C8 MGT B 1 9.633 4.953 -24.839 1.00 26.32 C

ANISOU 6545 C8 MGT B 1 2789 3772 3439 259 -650 -132 C

ATOM 6546 N7 MGT B 1 10.913 4.962 -24.399 1.00 26.18 N

ANISOU 6546 N7 MGT B 1 2885 3627 3435 179 -562 -155 N

ATOM 6547 CM7 MGT B 1 11.908 3.911 -24.712 1.00 23.88 C

ANISOU 6547 CM7 MGT B 1 2618 3350 310.

33. 517 -218 C

ATOM 6548 C5 MGT B 1 11.150 6.053 -23.649 1.00 26.92 C

ANISOU 6548 C5 MGT B 1 3066 3581 3583 257 -521 -117 C

ATOM 6549 C4 MGT B 1 9.951 6.759 -23.616 1.00 26.32 C

ANISOU 6549 C4 MGT B 1 2937 3533 3529 418 -573 -67 C

ATOM 6550 N3 MGT B 1 9.832 7.907 -22.934 1.00 26.49 N

ANISOU 6550 N3 MGT B 1 3046 3417 3601 542 -541 -32 N

ATOM 6551 C2 MGT B 1 10.866 8.432 -22.259 1.00 27.34 C

ANISOU 6551 C2 MGT B 1 3301 3354 3732 486 -471 -49 C

ATOM 6552 N2 MGT B 1 10.701 9.584 -21.612 1.00 27.16 N

ANISOU 6552 N2 MGT B 1 3394 3178 3749 604 -444 -27 N

ATOM 6553 N1 MGT B 1 12.111 7.743 -22.231 1.00 25.77 N

ANISOU 6553 N1 MGT B 1 3131 3144 3516 307 -431 -94 N

ATOM 6554 C6 MGT B 1 12.248 6.556 -22.934 1.00 25.10 C

ANISOU 6554 C6 MGT B 1 2952 3198 3385 209 -450 -125 C

ATOM 6555 O6 MGT B 1 13.319 5.964 -22.921 1.00 23.93 O

ANISOU 6555 O6 MGT B 1 2823 3040 322.

85. 407 -162 O

ATOM 6556 O2G MGT D 1 61.475 -17.770 -25.548 1.00 67.38 O

ANISOU 6556 O2G MGT D 1 9188 7995 8420 107 942 -1582 O

ATOM 6557 PG MGT D 1 62.375 -16.755 -24.687 1.00 63.67 P

ANISOU 6557 PG MGT D 1 8522 7594 8077 197 990 -1352 P

ATOM 6558 O3G MGT D 1 61.503 -15.362 -24.545 1.00 60.97 O

ANISOU 6558 O3G MGT D 1 8082 7476 7609 96 876 -1228 O

ATOM 6559 O1G MGT D 1 62.653 -17.429 -23.397 1.00 61.93 O

ANISOU 6559 O1G MGT D 1 8255 7184 8089 201 946 -1268 O

ATOM 6560 O3B MGT D 1 63.673 -16.536 -25.716 1.00 64.52 O

ANISOU 6560 O3B MGT D 1 8633 7752 8130 376 1208 -1392 O

ATOM 6561 PB MGT D 1 64.918 -15.449 -25.741 1.00 62.58 P

ANISOU 6561 PB MGT D 1 8215 7622 7940 497 1355 -1237 P

ATOM 6562 O2B MGT D 1 65.139 -15.212 -27.321 1.00 64.91 O

ANISOU 6562 O2B MGT D 1 8631 8045 7988 558 1524 -1348 O

ATOM 6563 O1B MGT D 1 66.180 -15.970 -25.139 1.00 63.51 O

ANISOU 6563 O1B MGT D 1 8220 7601 8311 635 1450 -1195 O

ATOM 6564 O3A MGT D 1 64.421 -13.964 -25.210 1.00 59.32 O

ANISOU 6564 O3A MGT D 1 7676 7379 7485 401 1242 -1049 O

ATOM 6565 PA MGT D 1 65.432 -12.750 -24.675 1.00 56.96 P

ANISOU 6565 PA MGT D 1 7170 7154 7317 450 1303 -853 P

ATOM 6566 O2A MGT D 1 64.807 -11.421 -25.326 1.00 57.92 O

ANISOU 6566 O2A MGT D 1 7315 7462 7229 384 1286 -780 O

ATOM 6567 O1A MGT D 1 66.884 -12.915 -25.008 1.00 57.06 O

ANISOU 6567 O1A MGT D 1 7089 7135 7457 589 1504 -851 O

ATOM 6568 O5* MGT D 1 65.125 -12.590 -23.090 1.00 52.24 O

ANISOU 6568 O5* MGT D 1 6467 6494 6888 382 1121 -735 O

ATOM 6569 C5* MGT D 1 66.139 -12.982 -22.146 1.00 47.19 C

ANISOU 6569 C5* MGT D 1 5707 5738 6485 461 1122 -671 C

ATOM 6570 C4* MGT D 1 65.571 -13.910 -21.075 1.00 41.42 C

ANISOU 6570 C4* MGT D 1 5036 4863 5837 416 977 -675 C

ATOM 6571 O4* MGT D 1 64.237 -13.425 -20.723 1.00 38.14 O

ANISOU 6571 O4* MGT D 1 4670 4525 5297 270 847 -650 O

ATOM 6572 C3* MGT D 1 65.400 -15.351 -21.574 1.00 41.82 C

ANISOU 6572 C3* MGT D 1 5242 4761 5887 450 1023 -828 C

ATOM 6573 O3* MGT D 1 66.052 -16.225 -20.646 1.00 42.77 O

ANISOU 6573 O3* MGT D 1 5339 4701 6212 533 987 -785 O

ATOM 6574 C2* MGT D 1 63.880 -15.578 -21.583 1.00 38.52 C

ANISOU 6574 C2* MGT D 1 4952 4355 5329 288 909 -890 C

ATOM 6575 O2* MGT D 1 63.571 -16.924 -21.181 1.00 41.39 O

ANISOU 6575 O2* MGT D 1 5434 4513 5779 262 869 -960 O

ATOM 6576 C1* MGT D 1 63.397 -14.606 -20.531 1.00 32.26 C

ANISOU 6576 C1* MGT D 1 4058 3655 4544 202 787 -739 C

ATOM 6577 N9 MGT D 1 61.985 -14.077 -20.575 1.00 30.62 N

ANISOU 6577 N9 MGT D 1 3877 3566 4190 57 691 -749 N

ATOM 6578 C8 MGT D 1 61.537 -13.152 -21.455 1.00 28.56 C

ANISOU 6578 C8 MGT D 1 3608 3474 3770 36 699 -767 C

ATOM 6579 N7 MGT D 1 60.245 -12.956 -21.135 1.00 28.87 N

ANISOU 6579 N7 MGT D 1 3649 3576 3745 -86 585 -769 N

ATOM 6580 CM7 MGT D 1 59.372 -12.016 -21.848 1.00 27.27 C

ANISOU 6580 CM7 MGT D 1 3432 3551 3377 -125 533 -779 C

ATOM 6581 C5 MGT D 1 59.872 -13.721 -20.082 1.00 29.90 C

ANISOU 6581 C5 MGT D 1 3792 3586 3983 -156 529 -750 C

ATOM 6582 C4 MGT D 1 61.017 -14.436 -19.739 1.00 29.44 C

ANISOU 6582 C4 MGT D 1 3754 3372 4059 -59 592 -730 C

ATOM 6583 N3 MGT D 1 61.004 -15.292 -18.702 1.00 29.19 N

ANISOU 6583 N3 MGT D 1 3760 3183 4146 -86 553 -685 N

ATOM 6584 C2 MGT D 1 59.915 -15.502 -17.954 1.00 28.05 C

ANISOU 6584 C2 MGT D 1 3637 3026 3992 -223 481 -658 C

ATOM 6585 N2 MGT D 1 59.978 -16.375 -16.971 1.00 29.73 N

ANISOU 6585 N2 MGT D 1 3915 3072 4309 -246 463 -596 N

ATOM 6586 N1 MGT D 1 58.740 -14.829 -18.230 1.00 27.16 N

ANISOU 6586 N1 MGT D 1 3479 3073 3767 -332 434 -687 N

ATOM 6587 C6 MGT D 1 58.701 -13.917 -19.293 1.00 28.79 C

ANISOU 6587 C6 MGT D 1 3642 3444 3853 -290 443 -733 C

ATOM 6588 O6 MGT D 1 57.638 -13.327 -19.502 1.00 27.71 O

ANISOU 6588 O6 MGT D 1 3458 3444 3626 -368 381 -750 O

ATOM 6589 O2G MGT E 1 23.200 -31.391 -24.125 1.00 70.75 O

ANISOU 6589 O2G MGT E 1 9036 8796 9051 -973 -263 -1625 O

ATOM 6590 PG MGT E 1 23.830 -31.142 -22.645 1.00 68.95 P

ANISOU 6590 PG MGT E 1 8848 8360 8991 -906 -117 -1455 P

ATOM 6591 O3G MGT E 1 24.816 -29.813 -22.701 1.00 67.49 O

ANISOU 6591 O3G MGT E 1 8750 8226 8668 -768 -101 -1258 O

ATOM 6592 O1G MGT E 1 22.748 -30.981 -21.631 1.00 68.11 O

ANISOU 6592 O1G MGT E 1 8612 8217 9051 -935 -125 -1397 O

ATOM 6593 O3B MGT E 1 24.889 -32.361 -22.338 1.00 67.54 O

ANISOU 6593 O3B MGT E 1 8779 7972 8911 -938.

27. 1554 O

ATOM 6594 PB MGT E 1 24.785 -33.870 -22.938 1.00 68.18 P

ANISOU 6594 PB MGT E 1 8880 7968 9058 -1057.

39. 1813 P

ATOM 6595 O2B MGT E 1 25.148 -33.733 -24.532 1.00 69.37 O

ANISOU 6595 O2B MGT E 1 9066 8338 8953 -1050 -28 -1961 O

ATOM 6596 O1B MGT E 1 23.440 -34.487 -22.726 1.00 68.87 O

ANISOU 6596 O1B MGT E 1 8856 8032 9278 -1201 -15 -1906 O

ATOM 6597 O3A MGT E 1 25.997 -34.776 -22.240 1.00 65.43 O

ANISOU 6597 O3A MGT E 1 8646 7350 8863 -1017 183 -1825 O

ATOM 6598 PA MGT E 1 27.307 -34.306 -21.288 1.00 59.20 P

ANISOU 6598 PA MGT E 1 7934 6449 8110 -875 286 -1635 P

ATOM 6599 O2A MGT E 1 28.136 -33.197 -22.107 1.00 58.65 O

ANISOU 6599 O2A MGT E 1 7884 6588 7811 -779 280 -1588 O

ATOM 6600 O1A MGT E 1 28.129 -35.492 -20.942 1.00 59.66 O

ANISOU 6600 O1A MGT E 1 8071 6268 8331 -854 365 -1720 O

ATOM 6601 O5* MGT E 1 26.816 -33.620 -19.940 1.00 53.22 O

ANISOU 6601 O5* MGT E 1 7134 5651 7435 -863 299 -1411 O

ATOM 6602 C5* MGT E 1 26.613 -34.401 -18.761 1.00 47.71 C

ANISOU 6602 C5* MGT E 1 6458 4745 6925 -918 359 -1351 C

ATOM 6603 C4* MGT E 1 25.456 -33.830 -17.966 1.00 43.86 C

ANISOU 6603 C4* MGT E 1 5872 4324 6467 -983 346 -1240 C

ATOM 6604 O4* MGT E 1 25.786 -32.441 -17.660 1.00 39.94 O

ANISOU 6604 O4* MGT E 1 5354 3955 5866 -865 338 -1094 O

ATOM 6605 C3* MGT E 1 24.198 -33.807 -18.837 1.00 44.21 C

ANISOU 6605 C3* MGT E 1 5798 4523 6477 -1082 252 -1373 C

ATOM 6606 O3* MGT E 1 23.129 -34.318 -18.052 1.00 47.14 O

ANISOU 6606 O3* MGT E 1 6089 4833 6988 -1223 283 -1368 O

ATOM 6607 C2* MGT E 1 23.967 -32.325 -19.118 1.00 42.11 C

ANISOU 6607 C2* MGT E 1 5461 4470 6071 -979 178 -1280 C

ATOM 6608 O2* MGT E 1 22.556 -32.080 -19.141 1.00 44.49 O

ANISOU 6608 O2* MGT E 1 5604 4894 6405 -1051 104 -1318 O

ATOM 6609 C1* MGT E 1 24.614 -31.665 -17.889 1.00 36.11 C

ANISOU 6609 C1* MGT E 1 4744 3637 5341 -890 263 -1094 C

ATOM 6610 N9 MGT E 1 25.074 -30.253 -17.973 1.00 33.69 N

ANISOU 6610 N9 MGT E 1 4442 3438 4921 -758 232 -977 N

ATOM 6611 C8 MGT E 1 26.143 -29.848 -18.690 1.00 32.33 C

ANISOU 6611 C8 MGT E 1 4355 3300 4628 -678 226 -961 C

ATOM 6612 N7 MGT E 1 26.235 -28.515 -18.497 1.00 30.39 N

ANISOU 6612 N7 MGT E 1 4097 3125 4326 -592 200 -834 N

ATOM 6613 CM7 MGT E 1 27.291 -27.689 -19.147 1.00 30.36 C

ANISOU 6613 CM7 MGT E 1 4173 3175 4187 -519 196 -768 C

ATOM 6614 C5 MGT E 1 25.270 -28.075 -17.684 1.00 30.41 C

ANISOU 6614 C5 MGT E 1 4001 3137 4414 -594 187 -790 C

ATOM 6615 C4 MGT E 1 24.528 -29.207 -17.348 1.00 33.54 C

ANISOU 6615 C4 MGT E 1 4345 3484 4915 -708 216 -881 C

ATOM 6616 N3 MGT E 1 23.454 -29.116 -16.532 1.00 32.74 N

ANISOU 6616 N3 MGT E 1 4124 3405 4909 -756 232 -876 N

ATOM 6617 C2 MGT E 1 23.082 -27.949 -16.013 1.00 31.10 C

ANISOU 6617 C2 MGT E 1 3842 3265 4708 -674 218 -805 C

ATOM 6618 N2 MGT E 1 22.036 -27.912 -15.215 1.00 32.01 N

ANISOU 6618 N2 MGT E 1 3821 3423 4917 -724 252 -831 N

ATOM 6619 N1 MGT E 1 23.783 -26.786 -16.310 1.00 30.29 N

ANISOU 6619 N1 MGT E 1 3801 3183 4526 -545 175 -716 N

ATOM 6620 C6 MGT E 1 24.887 -26.830 -17.148 1.00 31.43 C

ANISOU 6620 C6 MGT E 1 4072 3309 4562 -516 162 -696 C

ATOM 6621 O6 MGT E 1 25.482 -25.774 -17.398 1.00 30.00 O

ANISOU 6621 O6 MGT E 1 3944 3144 4312 -429 135 -607 O

ATOM 6622 O2G MGT F 1 30.350 -3.944 -65.480 1.00 99.58 O

ANISOU 6622 O2G MGT F 1 14031 16156 7647 -644.

2. 439 O

ATOM 6623 PG MGT F 1 28.875 -4.380 -64.937 1.00 97.98 P

ANISOU 6623 PG MGT F 1 13719 15816 7693 -487 -380 -489 P

ATOM 6624 O3G MGT F 1 28.278 -5.473 -65.973 1.00100.06 O

ANISOU 6624 O3G MGT F 1 14125 16190 7703 -469 -516 -718 O

ATOM 6625 O1G MGT F 1 28.966 -4.930 -63.549 1.00 93.98 O

ANISOU 6625 O1G MGT F 1 12887 15191 7630 -397 -325 -595 O

ATOM 6626 O3B MGT F 1 27.926 -3.048 -65.157 1.00 97.20 O

ANISOU 6626 O3B MGT F 1 13810 15616 7506 -472 -688 -195 O

ATOM 6627 PB MGT F 1 26.314 -3.046 -64.848 1.00 94.58 P

ANISOU 6627 PB MGT F 1 13385 15180 7372 -321 -1114 -191 P

ATOM 6628 O2B MGT F 1 25.693 -3.980 -66.039 1.00 96.13 O

ANISOU 6628 O2B MGT F 1 13730 15529 7265 -323 -1304 -385 O

ATOM 6629 O1B MGT F 1 25.707 -1.684 -64.850 1.00 95.46 O

ANISOU 6629 O1B MGT F 1 13630 15170 7470 -262 -1343 89 O

ATOM 6630 O3A MGT F 1 26.194 -3.836 -63.403 1.00 86.47 O

ANISOU 6630 O3A MGT F 1 11980 14048 6828 -253 -1036 -362 O

ATOM 6631 PA MGT F 1 25.747 -3.160 -61.969 1.00 79.76 P

ANISOU 6631 PA MGT F 1 10904 13006 6395 -173 -1093 -247 P

ATOM 6632 O2A MGT F 1 25.428 -4.445 -61.045 1.00 77.01 O

ANISOU 6632 O2A MGT F 1 10293 12609 6357 -138 -1050 -494 O

ATOM 6633 O1A MGT F 1 24.575 -2.250 -62.103 1.00 81.05 O

ANISOU 6633 O1A MGT F 1 11113 13096 6587 -75 -1414 -96 O

ATOM 6634 O5* MGT F 1 27.022 -2.434 -61.277 1.00 74.56 O

ANISOU 6634 O5* MGT F 1 10228 12289 5813 -247 -803 -111 O

ATOM 6635 C5* MGT F 1 27.118 -0.995 -61.342 1.00 70.02 C

ANISOU 6635 C5* MGT F 1 9816 11623 5166 -279 -837 152 C

ATOM 6636 C4* MGT F 1 28.554 -0.539 -61.633 1.00 66.55 C

ANISOU 6636 C4* MGT F 1 9491 11251 4545 -450 -529 235 C

ATOM 6637 O4* MGT F 1 29.365 -1.421 -60.821 1.00 62.48 O

ANISOU 6637 O4* MGT F 1 8711 10787 4243 -457 -310 45 O

ATOM 6638 C3* MGT F 1 29.017 -0.716 -63.097 1.00 67.92 C

ANISOU 6638 C3* MGT F 1 9926 11602 4279 -559 -437 229 C

ATOM 6639 O3* MGT F 1 29.464 0.547 -63.638 1.00 71.23 O

ANISOU 6639 O3* MGT F 1 10633 11975 4455 -700 -363 483 O

ATOM 6640 C2* MGT F 1 30.204 -1.684 -63.020 1.00 65.40 C

ANISOU 6640 C2* MGT F 1 9433 11442 3975 -628 -112 11 C

ATOM 6641 O2* MGT F 1 31.280 -1.234 -63.872 1.00 65.11 O

ANISOU 6641 O2* MGT F 1 9573 11538 3626 -817 163 74 O

ATOM 6642 C1* MGT F 1 30.610 -1.563 -61.542 1.00 60.72 C

ANISOU 6642 C1* MGT F 1 8551 10736 3784 -595 -29 0 C

ATOM 6643 N9 MGT F 1 31.361 -2.695 -60.897 1.00 58.13 N

ANISOU 6643 N9 MGT F 1 7951 10481 3654 -540 147 -237 N

ATOM 6644 C8 MGT F 1 30.774 -3.809 -60.424 1.00 56.15 C

ANISOU 6644 C8 MGT F 1 7571 10180 3582 -396.

36. 414 C

ATOM 6645 N7 MGT F 1 31.776 -4.546 -59.912 1.00 55.98 N

ANISOU 6645 N7 MGT F 1 7360 10216 3694 -359 232 -573 N

ATOM 6646 CM7 MGT F 1 31.556 -5.890 -59.278 1.00 54.61 C

ANISOU 6646 CM7 MGT F 1 7057 9970 3722 -208 191 -783 C

ATOM 6647 C5 MGT F 1 32.960 -3.927 -60.039 1.00 57.17 C

ANISOU 6647 C5 MGT F 1 7463 10481 3778 -476 459 -522 C

ATOM 6648 C4 MGT F 1 32.671 -2.722 -60.675 1.00 58.35 C

ANISOU 6648 C4 MGT F 1 7834 10615 3719 -617 418 -299 C

ATOM 6649 N3 MGT F 1 33.637 -1.831 -60.974 1.00 59.84 N

ANISOU 6649 N3 MGT F 1 8063 10888 3784 -804 632 -191 N

ATOM 6650 C2 MGT F 1 34.924 -2.053 -60.665 1.00 60.72 C

ANISOU 6650 C2 MGT F 1 7940 11139 3992 -862 890 -315 C

ATOM 6651 N2 MGT F 1 35.834 -1.129 -60.973 1.00 62.34 N

ANISOU 6651 N2 MGT F 1 8169 11434 4084 -1091 1115 -218 N

ATOM 6652 N1 MGT F 1 35.287 -3.254 -60.011 1.00 59.54 N

ANISOU 6652 N1 MGT F 1 7525 11029 4067 -680 912 -549 N

ATOM 6653 C6 MGT F 1 34.299 -4.207 -59.684 1.00 57.63 C

ANISOU 6653 C6 MGT F 1 7300 10661 3935 -485 696 -642 C

ATOM 6654 O6 MGT F 1 34.635 -5.252 -59.114 1.00 55.72 O

ANISOU 6654 O6 MGT F 1 6882 10416 3874 -329 718 -828 O

ATOM 6655 OH2 WAT Z 1 22.010 -17.664 -4.923 1.00 24.01 O

ATOM 6656 OH2 WAT Z 2 35.587 -15.501 -13.579 1.00 25.92 O

ATOM 6657 OH2 WAT Z 3 24.874 18.972 -29.481 1.00 17.82 O

ATOM 6658 OH2 WAT Z 4 22.669 -1.536 -24.962 1.00 13.35 O

ATOM 6659 OH2 WAT Z 5 52.591 -14.211 -5.902 1.00 21.48 O

ATOM 6660 OH2 WAT Z 7 13.160 0.537 1.189 1.00 23.18 O

ATOM 6661 OH2 WAT Z 8 25.007 17.823 -32.038 1.00 17.76 O

ATOM 6662 OH2 WAT Z 9 57.764 0.177 -1.188 1.00 25.56 O

ATOM 6663 OH2 WAT Z 10 22.557 -2.907 -16.078 1.00 29.94 O

ATOM 6664 OH2 WAT Z 11 0.415 -4.929 -12.849 1.00 25.54 O

ATOM 6665 OH2 WAT Z 12 21.159 3.266 -9.320 1.00 33.91 O

ATOM 6666 OH2 WAT Z 13 29.894 16.381 -39.221 1.00 27.21 O

ATOM 6667 OH2 WAT Z 14 48.790 14.910 -10.474 1.00 28.71 O

ATOM 6668 OH2 WAT Z 15 51.978 -20.700 -11.448 1.00 26.98 O

ATOM 6669 OH2 WAT Z 16 52.522 8.682 -31.531 1.00 27.48 O

ATOM 6670 OH2 WAT Z 17 71.301 -1.768 -14.451 1.00 22.48 O

ATOM 6671 OH2 WAT Z 18 27.320 -22.307 -20.123 1.00 19.55 O

ATOM 6672 OH2 WAT Z 19 34.964 21.944 -4.871 1.00 23.06 O

ATOM 6673 OH2 WAT Z 21 23.902 -22.328 -16.923 1.00 23.97 O

ATOM 6674 OH2 WAT Z 22 48.357 -2.830 -15.780 1.00 34.81 O

ATOM 6675 OH2 WAT Z 23 58.588 5.961 -27.382 1.00 19.01 O

ATOM 6676 OH2 WAT Z 24 18.628 15.589 -17.793 1.00 30.46 O

ATOM 6677 OH2 WAT Z 25 19.270 -18.539 -13.641 1.00 21.85 O

ATOM 6678 OH2 WAT Z 26 43.558 13.915 -26.424 1.00 17.33 O

ATOM 6679 OH2 WAT Z 27 26.542 -12.581 -16.266 1.00 26.41 O

ATOM 6680 OH2 WAT Z 28 34.875 33.272 -20.697 1.00 21.41 O

ATOM 6681 OH2 WAT Z 29 13.457 -11.350 -34.721 1.00 35.91 O

ATOM 6682 OH2 WAT Z 30 25.564 10.236 -30.803 1.00 24.48 O

ATOM 6683 OH2 WAT Z 31 45.958 -26.847 -21.485 1.00 27.96 O

ATOM 6684 OH2 WAT Z 32 35.988 -22.594 2.913 1.00 21.42 O

ATOM 6685 OH2 WAT Z 33 54.562 -14.794 -17.888 1.00 22.27 O

ATOM 6686 OH2 WAT Z 34 22.529 2.193 -30.694 1.00 27.64 O

ATOM 6687 OH2 WAT Z 35 25.635 -4.794 -32.881 1.00 28.73 O

ATOM 6688 OH2 WAT Z 36 27.823 20.133 -0.039 1.00 36.81 O

ATOM 6689 OH2 WAT Z 37 20.246 12.658 -31.810 1.00 24.61 O

ATOM 6690 OH2 WAT Z 38 28.300 -37.005 -18.759 1.00 51.31 O

ATOM 6691 OH2 WAT Z 39 53.886 -12.268 -21.629 1.00 17.36 O

ATOM 6692 OH2 WAT Z 40 48.741 -7.083 -24.282 1.00 24.97 O

ATOM 6693 OH2 WAT Z 41 56.501 -23.941 -22.749 1.00 33.42 O

ATOM 6694 OH2 WAT Z 42 70.436 0.347 -12.882 1.00 19.32 O

ATOM 6695 OH2 WAT Z 43 25.679 6.098 -19.237 1.00 22.39 O

ATOM 6696 OH2 WAT Z 44 32.839 32.448 -18.714 1.00 35.80 O

ATOM 6697 OH2 WAT Z 45 13.259 -14.963 -26.829 1.00 23.85 O

ATOM 6698 OH2 WAT Z 46 45.572 -27.223 -24.539 1.00 26.82 O

ATOM 6699 OH2 WAT Z 47 18.892 12.226 -9.507 1.00 24.12 O

ATOM 6700 OH2 WAT Z 48 15.179 -6.957 4.889 1.00 33.18 O

ATOM 6701 OH2 WAT Z 49 28.351 4.517 -12.106 1.00 29.12 O

ATOM 6702 OH2 WAT Z 50 69.753 -7.784 -22.150 1.00 24.16 O

ATOM 6703 OH2 WAT Z 51 51.484 -18.920 -13.213 1.00 25.28 O

ATOM 6704 OH2 WAT Z 52 30.860 13.483 -5.891 1.00 23.31 O

ATOM 6705 OH2 WAT Z 53 30.542 -37.628 -17.641 1.00 34.32 O

ATOM 6706 OH2 WAT Z 54 17.077 -19.149 -12.084 1.00 24.17 O

ATOM 6707 OH2 WAT Z 55 31.540 -38.915 -14.093 1.00 29.25 O

ATOM 6708 OH2 WAT Z 56 32.031 10.317 -7.068 1.00 23.87 O

ATOM 6709 OH2 WAT Z 57 63.159 -12.048 -28.694 1.00 38.66 O

ATOM 6710 OH2 WAT Z 60 32.626 -17.204 -22.492 1.00 28.77 O

ATOM 6711 OH2 WAT Z 61 13.024 -14.857 -24.008 1.00 21.66 O

ATOM 6712 OH2 WAT Z 62 16.501 7.671 -21.877 1.00 22.39 O

ATOM 6713 OH2 WAT Z 63 26.459 8.287 -33.540 1.00 44.16 O

ATOM 6714 OH2 WAT Z 64 51.383 -16.236 -0.275 1.00 35.25 O

ATOM 6715 OH2 WAT Z 65 55.449 4.737 -37.070 1.00 38.33 O

ATOM 6716 OH2 WAT Z 66 18.627 -7.775 -42.508 1.00 43.11 O

ATOM 6717 OH2 WAT Z 67 25.172 -1.387 -16.895 1.00 32.89 O

ATOM 6718 OH2 WAT Z 68 63.541 6.400 3.498 1.00 39.85 O

ATOM 6719 OH2 WAT Z 69 58.234 5.010 -30.073 1.00 27.73 O

ATOM 6720 OH2 WAT Z 70 40.724 12.891 -10.774 1.00 30.83 O

ATOM 6721 OH2 WAT Z 71 24.900 12.576 -19.843 1.00 20.19 O

ATOM 6722 OH2 WAT Z 72 49.784 -6.304 -7.577 1.00 31.08 O

ATOM 6723 OH2 WAT Z 73 27.087 40.698 -13.760 1.00 41.38 O

ATOM 6724 OH2 WAT Z 74 76.962 7.731 -7.980 1.00 33.08 O

ATOM 6725 OH2 WAT Z 75 23.651 14.328 -38.716 1.00 32.75 O

ATOM 6726 OH2 WAT Z 76 11.075 7.898 -8.738 1.00 37.62 O

ATOM 6727 OH2 WAT Z 77 17.338 4.404 -24.665 1.00 17.00 O

ATOM 6728 OH2 WAT Z 78 16.077 -25.529 -23.013 1.00 30.89 O

ATOM 6729 OH2 WAT Z 79 53.527 14.001 -17.979 1.00 27.27 O

ATOM 6730 OH2 WAT Z 80 34.264 14.194 -45.137 1.00 32.07 O

ATOM 6731 OH2 WAT Z 82 42.478 -8.305 -9.650 1.00 29.55 O

ATOM 6732 OH2 WAT Z 83 15.985 -6.541 -42.463 1.00 28.85 O

ATOM 6733 OH2 WAT Z 84 34.516 8.340 -25.756 1.00 25.94 O

ATOM 6734 OH2 WAT Z 85 58.379 -1.510 -36.376 1.00 38.41 O

ATOM 6735 OH2 WAT Z 86 37.811 8.922 -27.105 1.00 22.11 O

ATOM 6736 OH2 WAT Z 87 -0.391 -3.769 -14.739 1.00 35.30 O

ATOM 6737 OH2 WAT Z 88 43.490 14.702 -6.036 1.00 32.76 O

ATOM 6738 OH2 WAT Z 89 66.881 0.967 -35.813 1.00 29.64 O

ATOM 6739 OH2 WAT Z 90 50.228 23.440 -23.336 1.00 25.56 O

ATOM 6740 OH2 WAT Z 91 18.346 -19.140 -26.919 1.00 38.45 O

ATOM 6741 OH2 WAT Z 93 33.957 31.768 -27.497 1.00 34.70 O

ATOM 6742 OH2 WAT Z 94 15.782 16.563 -13.960 1.00 25.91 O

ATOM 6743 OH2 WAT Z 95 48.925 4.506 4.193 1.00 30.06 O

ATOM 6744 OH2 WAT Z 96 55.094 8.303 2.407 1.00 32.94 O

ATOM 6745 OH2 WAT Z 97 23.845 23.584 -12.034 1.00 27.82 O

ATOM 6746 OH2 WAT Z 98 19.282 13.117 -18.942 1.00 28.06 O

ATOM 6747 OH2 WAT Z 99 21.689 -13.748 -35.649 1.00 30.66 O

ATOM 6748 OH2 WAT Z 100 30.856 27.498 -24.106 1.00 31.84 O

ATOM 6749 OH2 WAT Z 101 46.475 15.139 -23.225 1.00 30.44 O

ATOM 6750 OH2 WAT Z 102 75.808 3.111 -8.446 1.00 33.80 O

ATOM 6751 OH2 WAT Z 103 22.117 -4.088 -48.032 1.00 47.28 O

ATOM 6752 OH2 WAT Z 104 19.417 -9.956 -43.103 1.00 37.00 O

ATOM 6753 OH2 WAT Z 105 50.959 14.958 -6.038 1.00 28.24 O

ATOM 6754 OH2 WAT Z 106 12.824 -14.262 -55.184 1.00 53.76 O

ATOM 6755 OH2 WAT Z 107 24.243 -15.291 -17.663 1.00 39.66 O

ATOM 6756 OH2 WAT Z 108 42.270 21.564 -34.734 1.00 24.55 O

ATOM 6757 OH2 WAT Z 109 16.713 -20.968 -7.090 1.00 27.98 O

ATOM 6758 OH2 WAT Z 110 36.477 -16.419 -21.410 1.00 48.83 O

ATOM 6759 OH2 WAT Z 111 35.351 16.445 -10.062 1.00 50.87 O

ATOM 6760 OH2 WAT Z 112 24.841 -4.261 -4.666 1.00 30.33 O

ATOM 6761 OH2 WAT Z 113 4.786 -8.000 -18.626 1.00 35.35 O

ATOM 6762 OH2 WAT Z 114 10.306 -1.689 -38.133 1.00 26.41 O

ATOM 6763 OH2 WAT Z 115 42.924 -19.244 -23.456 1.00 34.89 O

ATOM 6764 OH2 WAT Z 116 42.206 12.907 -6.861 1.00 25.28 O

ATOM 6765 OH2 WAT Z 117 51.605 13.100 -19.296 1.00 31.95 O

ATOM 6766 OH2 WAT Z 118 16.469 13.514 -8.427 1.00 45.86 O

ATOM 6767 OH2 WAT Z 119 50.036 4.161 -29.744 1.00 25.55 O

ATOM 6768 OH2 WAT Z 120 16.233 10.887 -35.555 1.00 41.62 O

ATOM 6769 OH2 WAT Z 121 22.532 0.490 -33.852 1.00 27.81 O

ATOM 6770 OH2 WAT Z 123 19.367 -19.611 -56.734 1.00 31.09 O

ATOM 6771 OH2 WAT Z 124 46.548 -25.852 -32.207 1.00 41.02 O

ATOM 6772 OH2 WAT Z 125 27.102 -32.879 -5.267 1.00 28.86 O

ATOM 6773 OH2 WAT Z 126 49.465 4.075 -4.211 1.00 29.62 O

ATOM 6774 OH2 WAT Z 127 68.660 -0.401 -18.608 1.00 38.81 O

ATOM 6775 OH2 WAT Z 128 28.488 -14.653 -2.031 1.00 33.34 O

ATOM 6776 OH2 WAT Z 129 38.691 29.556 -29.045 1.00 27.56 O

ATOM 6777 OH2 WAT Z 130 20.046 14.970 -5.630 1.00 35.59 O

ATOM 6778 OH2 WAT Z 131 21.161 -5.035 -2.609 1.00 24.94 O

ATOM 6779 OH2 WAT Z 132 39.421 -26.828 9.622 1.00 57.63 O

ATOM 6780 OH2 WAT Z 133 30.273 -15.692 -5.914 1.00 26.45 O

ATOM 6781 OH2 WAT Z 134 40.038 -33.801 -13.906 1.00 35.26 O

ATOM 6782 OH2 WAT Z 135 50.389 2.298 -27.656 1.00 26.52 O

ATOM 6783 OH2 WAT Z 136 42.086 7.582 -31.511 1.00 36.58 O

ATOM 6784 OH2 WAT Z 137 50.049 -21.915 -25.630 1.00 29.44 O

ATOM 6785 OH2 WAT Z 138 54.096 17.394 -14.365 1.00 26.83 O

ATOM 6786 OH2 WAT Z 139 53.457 22.759 -18.096 1.00 29.22 O

ATOM 6787 OH2 WAT Z 140 47.276 -14.555 -17.579 1.00 28.30 O

ATOM 6788 OH2 WAT Z 141 29.621 27.139 -8.722 1.00 19.74 O

ATOM 6789 OH2 WAT Z 142 21.551 -15.531 -46.177 1.00 37.12 O

ATOM 6790 OH2 WAT Z 143 0.081 -2.053 -6.723 1.00 35.12 O

ATOM 6791 OH2 WAT Z 145 2.708 -6.704 -12.288 1.00 29.20 O

ATOM 6792 OH2 WAT Z 146 48.187 -3.807 -23.913 1.00 39.45 O

ATOM 6793 OH2 WAT Z 147 35.518 -9.414 -58.946 1.00 49.19 O

ATOM 6794 OH2 WAT Z 149 50.661 6.651 -2.459 1.00 31.55 O

ATOM 6795 OH2 WAT Z 150 6.977 -4.292 5.382 1.00 33.62 O

ATOM 6796 OH2 WAT Z 151 70.053 -2.697 -21.777 1.00 35.37 O

ATOM 6797 OH2 WAT Z 152 26.405 -25.745 -56.037 1.00 54.31 O

ATOM 6798 OH2 WAT Z 153 21.807 -11.348 -34.300 1.00 36.00 O

ATOM 6799 OH2 WAT Z 155 61.988 12.944 -9.997 1.00 37.17 O

ATOM 6800 OH2 WAT Z 156 48.957 -7.172 -3.666 1.00 35.39 O

ATOM 6801 OH2 WAT Z 157 9.240 15.496 -16.665 1.00 37.22 O

ATOM 6802 OH2 WAT Z 158 22.966 -4.323 -23.838 1.00 42.19 O

ATOM 6803 OH2 WAT Z 159 4.714 -15.721 -5.172 1.00 39.15 O

ATOM 6804 OH2 WAT Z 160 23.677 12.223 -38.115 1.00 37.72 O

ATOM 6805 OH2 WAT Z 161 40.873 -28.484 -31.719 1.00 49.84 O

ATOM 6806 OH2 WAT Z 162 20.764 -17.215 -48.256 1.00 30.64 O

ATOM 6807 OH2 WAT Z 163 46.257 2.134 -5.934 1.00 28.45 O

ATOM 6808 OH2 WAT Z 164 1.102 -0.339 -23.846 1.00 33.06 O

ATOM 6809 OH2 WAT Z 165 56.153 -23.889 -11.833 1.00 51.89 O

ATOM 6810 OH2 WAT Z 166 46.513 -37.594 -25.306 1.00 42.87 O

ATOM 6811 OH2 WAT Z 167 31.205 -31.346 -33.201 1.00 37.47 O

ATOM 6812 OH2 WAT Z 168 46.736 -32.410 -16.066 1.00 48.36 O

ATOM 6813 OH2 WAT Z 169 16.920 -25.816 -15.401 1.00 43.16 O

ATOM 6814 OH2 WAT Z 170 40.084 28.332 -35.998 1.00 31.80 O

ATOM 6815 OH2 WAT Z 171 43.734 19.350 -33.881 1.00 29.51 O

ATOM 6816 OH2 WAT Z 172 26.493 -8.330 -14.753 1.00 32.62 O

ATOM 6817 OH2 WAT Z 173 33.748 4.983 -37.285 1.00 33.47 O

ATOM 6818 OH2 WAT Z 175 56.484 -13.704 -3.695 1.00 32.87 O

ATOM 6819 OH2 WAT Z 176 27.269 -8.161 -63.691 1.00 43.49 O

ATOM 6820 OH2 WAT Z 177 50.087 -8.525 -2.162 1.00 26.01 O

ATOM 6821 OH2 WAT Z 179 36.074 -14.083 -7.400 1.00 33.95 O

ATOM 6822 OH2 WAT Z 180 21.712 -14.738 -31.372 1.00 41.69 O

ATOM 6823 OH2 WAT Z 181 66.636 -9.970 -8.729 1.00 30.38 O

ATOM 6824 OH2 WAT Z 182 65.403 -12.027 -5.047 1.00 39.48 O

ATOM 6825 OH2 WAT Z 183 25.708 11.169 -43.671 1.00 35.61 O

ATOM 6826 OH2 WAT Z 184 51.471 -10.298 -38.366 1.00 45.24 O

ATOM 6827 OH2 WAT Z 185 13.816 14.588 -29.069 1.00 30.39 O

ATOM 6828 OH2 WAT Z 186 25.401 24.637 0.808 1.00 42.63 O

ATOM 6829 OH2 WAT Z 187 24.141 3.660 -9.953 1.00 41.40 O

ATOM 6830 OH2 WAT Z 188 50.530 -7.054 -30.104 1.00 37.25 O

ATOM 6831 OH2 WAT Z 189 17.307 -28.578 -8.340 1.00 37.35 O

ATOM 6832 OH2 WAT Z 190 23.215 -2.485 -9.503 1.00 34.35 O

ATOM 6833 OH2 WAT Z 191 25.409 -36.972 -21.377 1.00 28.84 O

ATOM 6834 OH2 WAT Z 192 32.293 9.056 -52.850 1.00 53.81 O

ATOM 6835 OH2 WAT Z 194 9.854 -20.178 -8.716 1.00 47.33 O

ATOM 6836 OH2 WAT Z 195 45.448 7.502 -21.691 1.00 37.17 O

ATOM 6837 OH2 WAT Z 196 41.211 -41.959 -28.245 1.00 48.32 O

ATOM 6838 OH2 WAT Z 197 35.027 -38.234 -17.129 1.00 46.15 O

ATOM 6839 OH2 WAT Z 198 30.945 3.849 -33.630 1.00 38.01 O

ATOM 6840 OH2 WAT Z 199 10.582 3.216 -30.915 1.00 30.78 O

ATOM 6841 OH2 WAT Z 200 38.611 -12.140 -47.412 1.00 34.67 O

ATOM 6842 OH2 WAT Z 201 17.623 19.014 -29.499 1.00 56.25 O

ATOM 6843 OH2 WAT Z 202 48.293 17.619 -42.569 1.00 39.31 O

ATOM 6844 OH2 WAT Z 203 28.384 15.063 -3.883 1.00 41.61 O

ATOM 6845 OH2 WAT Z 204 35.579 3.773 -42.257 1.00 44.44 O

ATOM 6846 OH2 WAT Z 205 20.437 -13.266 -15.586 1.00 23.67 O

ATOM 6847 OH2 WAT Z 206 38.154 5.184 -40.233 1.00 49.51 O

ATOM 6848 OH2 WAT Z 207 45.198 22.725 -11.680 1.00 41.39 O

ATOM 6849 OH2 WAT Z 208 36.171 -18.123 -57.255 1.00 45.32 O

ATOM 6850 OH2 WAT Z 209 20.057 7.547 -4.988 1.00 40.68 O

ATOM 6851 OH2 WAT Z 210 40.148 3.860 -50.600 1.00 35.38 O

ATOM 6852 OH2 WAT Z 211 45.636 -6.474 -29.807 1.00 52.09 O

ATOM 6853 OH2 WAT Z 212 45.277 22.770 -9.176 1.00 24.03 O

ATOM 6854 OH2 WAT Z 213 33.172 4.773 -32.693 1.00 35.71 O

ATOM 6855 OH2 WAT Z 214 33.650 -19.496 -30.848 1.00 39.27 O

ATOM 6856 OH2 WAT Z 215 46.592 -5.388 -49.721 1.00 39.74 O

ATOM 6857 OH2 WAT Z 216 35.963 -38.228 -8.201 1.00 32.99 O

ATOM 6858 OH2 WAT Z 217 42.449 -15.437 1.419 1.00 33.54 O

ATOM 6859 OH2 WAT Z 218 17.500 -25.027 -8.417 1.00 31.46 O

ATOM 6860 OH2 WAT Z 219 24.656 -8.332 -63.244 1.00 41.72 O

ATOM 6861 OH2 WAT Z 220 30.837 2.476 -36.522 1.00 34.45 O

ATOM 6862 OH2 WAT Z 221 54.803 -22.398 -30.205 1.00 48.05 O

ATOM 6863 OH2 WAT Z 222 46.624 -6.685 -7.840 1.00 45.14 O

ATOM 6864 OH2 WAT Z 223 69.977 0.204 -6.062 1.00 29.12 O

ATOM 6865 OH2 WAT Z 224 27.484 9.235 -45.269 1.00 41.47 O

ATOM 6866 OH2 WAT Z 225 39.053 12.272 -7.273 1.00 35.61 O

ATOM 6867 OH2 WAT Z 226 33.654 -11.620 -71.645 1.00 32.99 O

ATOM 6868 OH2 WAT Z 227 37.763 -36.609 -6.731 1.00 39.13 O

ATOM 6869 OH2 WAT Z 228 43.789 -6.817 -64.285 1.00 35.87 O

ATOM 6870 OH2 WAT Z 229 15.841 7.668 -39.846 1.00 42.57 O

ATOM 6871 OH2 WAT Z 230 49.470 -7.674 -32.876 1.00 39.94 O

ATOM 6872 OH2 WAT Z 231 73.132 -6.437 -11.485 1.00 43.64 O

ATOM 6873 OH2 WAT Z 232 69.189 -10.890 -8.124 1.00 43.10 O

ATOM 6874 OH2 WAT Z 233 68.220 1.931 -4.425 1.00 35.19 O

ATOM 6875 OH2 WAT Z 234 -0.117 0.428 -21.467 1.00 53.29 O

ATOM 6876 OH2 WAT Z 235 22.121 -3.444 6.017 1.00 34.04 O

ATOM 6877 OH2 WAT Z 236 12.296 14.675 -22.643 1.00 46.28 O

ATOM 6878 OH2 WAT Z 237 14.515 13.822 -6.990 1.00 44.07 O

ATOM 6879 OH2 WAT Z 238 8.264 1.618 -31.428 1.00 31.10 O

ATOM 6880 OH2 WAT Z 239 18.004 15.205 -9.508 1.00 43.87 O

ATOM 6881 OH2 WAT Z 240 26.138 -4.555 -6.867 1.00 38.79 O

ATOM 6882 OH2 WAT Z 241 44.614 6.587 -19.546 1.00 22.31 O

ATOM 6883 OH2 WAT Z 242 42.232 28.400 -29.247 1.00 39.83 O

ATOM 6884 OH2 WAT Z 243 35.090 10.219 -18.144 1.00 42.61 O

ATOM 6885 OH2 WAT Z 244 42.707 7.488 -22.667 1.00 26.48 O

ATOM 6886 OH2 WAT Z 245 5.481 -13.489 -33.682 1.00 42.88 O

ATOM 6887 OH2 WAT Z 246 24.380 4.187 -32.955 1.00 35.24 O

ATOM 6888 OH2 WAT Z 247 57.349 26.834 -15.600 1.00 57.46 O

ATOM 6889 OH2 WAT Z 248 36.055 -30.582 3.645 1.00 49.07 O

ATOM 6890 OH2 WAT Z 249 34.660 -36.210 -0.590 1.00 38.86 O

ATOM 6891 OH2 WAT Z 250 44.202 2.988 -16.631 1.00 34.41 O

ATOM 6892 OH2 WAT Z 251 28.312 -18.014 -27.408 1.00 47.07 O

ATOM 6893 OH2 WAT Z 252 43.871 7.890 -38.332 1.00 39.41 O

ATOM 6894 OH2 WAT Z 254 35.217 -18.557 -4.263 1.00 39.96 O

ATOM 6895 OH2 WAT Z 256 10.973 15.666 -13.469 1.00 51.73 O

ATOM 6896 OH2 WAT Z 257 63.806 8.757 -23.338 1.00 49.41 O

ATOM 6897 OH2 WAT Z 258 30.195 19.858 -45.928 1.00 40.05 O

ATOM 6898 OH2 WAT Z 259 45.473 -17.828 -14.547 1.00 34.13 O

ATOM 6899 OH2 WAT Z 261 32.026 -1.032 -32.780 1.00 55.96 O

ATOM 6900 OH2 WAT Z 263 11.334 -21.951 -13.454 1.00 54.94 O

ATOM 6901 OH2 WAT Z 264 34.852 11.262 -11.695 1.00 56.14 O

ATOM 6902 OH2 WAT Z 265 50.631 -23.856 -26.444 1.00 33.63 O

ATOM 6903 OH2 WAT Z 266 28.803 -8.481 0.380 1.00 46.99 O

ATOM 6904 OH2 WAT Z 268 60.910 -11.529 -36.250 1.00 42.92 O

ATOM 6905 OH2 WAT Z 269 29.242 24.796 -47.351 1.00 47.76 O

ATOM 6906 OH2 WAT Z 270 25.353 -10.071 -20.464 1.00 44.62 O

ATOM 6907 OH2 WAT Z 271 21.773 -15.534 -15.644 1.00 27.98 O

ATOM 6908 OH2 WAT Z 272 43.832 29.110 -16.193 1.00 29.32 O

ATOM 6909 OH2 WAT Z 274 24.253 7.923 -25.411 1.00 52.09 O

ATOM 6910 OH2 WAT Z 275 41.167 -6.372 -42.144 1.00 44.79 O

ATOM 6911 OH2 WAT Z 276 51.558 -15.128 -4.442 1.00 26.03 O

5 ATOM 6912 OH2 WAT Z 277 27.750 -30.861 -21.049 1.00 38.16 O

ATOM 6913 OH2 WAT Z 278 54.407 4.151 7.215 1.00 52.58 O

ATOM 6914 OH2 WAT Z 279 34.111 20.624 -3.191 1.00 50.26 O

ATOM 6915 OH2 WAT Z 280 47.178 7.039 -25.319 1.00 49.30 O

ATOM 6916 OH2 WAT Z 281 47.157 -37.019 -13.327 1.00 40.78 O

10 ATOM 6917 OH2 WAT Z 282 39.719 -34.762 -7.503 1.00 35.67 O

ATOM 6918 OH2 WAT Z 283 22.466 -13.541 -17.364 1.00 61.73 O

ATOM 6919 OH2 WAT Z 284 46.118 -4.589 -17.951 1.00 44.94 O

ATOM 6920 OH2 WAT Z 285 20.024 -16.482 -0.472 1.00 35.25 O

ATOM 6921 OH2 WAT Z 286 20.617 -3.221 -30.981 1.00 26.80 O

15 ATOM 6922 OH2 WAT Z 287 14.396 11.159 -7.209 1.00 48.86 O

ATOM 6923 OH2 WAT Z 288 1.963 6.454 -25.094 1.00 54.37 O

ATOM 6924 OH2 WAT Z 290 27.856 10.495 -28.946 1.00 31.74 O

ATOM 6925 OH2 WAT Z 291 20.937 -11.628 -24.894 1.00 33.25 O

ATOM 6926 OH2 WAT Z 293 29.682 29.704 -7.204 1.00 42.07 O

20 END